Caenorhabditis elegans

45 known processes

mec-8 (CELE_F46A9.6)

Protein MEC-8

mec-8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell projection organizationGO:00300302310.544
Zebrafish
embryo developmentGO:000979030520.422
embryo development ending in birth or egg hatchingGO:000979229920.409
cell part morphogenesisGO:00329901520.388
Zebrafish
multicellular organism reproductionGO:00325048190.383
cell projection morphogenesisGO:00488581480.298
Zebrafish
regulation of multicellular organismal processGO:00512397260.286
Fly
multi organism behaviorGO:00517053890.255
nervous system developmentGO:00073992530.235
cellular component morphogenesisGO:00329893180.233
Zebrafish
post embryonic developmentGO:000979121520.233
gene expressionGO:00104674120.230
neuron differentiationGO:00301822170.228
cell morphogenesis involved in differentiationGO:00009041120.223
Zebrafish
neuron projection developmentGO:00311751870.215
Zebrafish
cell morphogenesis involved in neuron differentiationGO:00486671110.208
Zebrafish
multi organism reproductive processGO:00447038670.207
cell developmentGO:00484686960.205
nucleic acid metabolic processGO:00903042990.205
regulation of multicellular organismal developmentGO:20000263170.193
genitalia developmentGO:00488067410.182
positive regulation of macromolecule metabolic processGO:00106041490.170
Human
cell motilityGO:00488703130.163
locomotionGO:004001116340.162
rna metabolic processGO:00160702280.161
sex differentiationGO:00075489090.155
sexual reproductionGO:00199535460.153
neuron projection guidanceGO:0097485820.141
nucleobase containing compound metabolic processGO:00061394060.139
regulation of gene expressionGO:00104683660.138
single organism reproductive processGO:004470211960.138
neuron developmentGO:00486661990.138
regulation of cellular macromolecule biosynthetic processGO:20001121880.137
regulation of developmental processGO:00507936840.135
Fly
negative regulation of biological processGO:00485195670.129
regulation of nematode larval developmentGO:00610622600.128
negative regulation of post embryonic developmentGO:00485812080.128
reproductive behaviorGO:00190983870.123
multi multicellular organism processGO:00447063900.117
establishment of localizationGO:005123411710.115
Human
transportGO:000681010930.114
Human
organ developmentGO:004851311020.114
cellular biosynthetic processGO:00442493150.111
positive regulation of multicellular organismal processGO:00512404170.111
behaviorGO:00076105270.105
localization of cellGO:00516743130.104
macromolecule localizationGO:00330367710.104
Human
signalingGO:00230524010.102
Human Fly
multicellular organismal reproductive behaviorGO:00330573840.101
regulation of cellular biosynthetic processGO:00313261890.100
Human
macromolecule biosynthetic processGO:00090592500.099
organic substance biosynthetic processGO:19015763230.099
multi organism reproductive behaviorGO:00447053870.097
endocytosisGO:00068978190.092
regulation of biological qualityGO:00650087410.092
cell cycle processGO:00224024820.092
cellular component movementGO:00069283880.089
cellular macromolecule biosynthetic processGO:00346452470.084
hermaphrodite genitalia developmentGO:00400357340.083
cell migrationGO:00164773060.083
developmental process involved in reproductionGO:000300611650.082
positive regulation of gene expressionGO:00106281120.082
axonogenesisGO:00074091020.078
regulation of macromolecule biosynthetic processGO:00105561890.077
Human
single organism signalingGO:00447004010.077
Human Fly
regulation of post embryonic developmentGO:00485802600.077
positive regulation of developmental processGO:00510944080.077
regulation of nitrogen compound metabolic processGO:00511712220.076
Human
regulation of macromolecule metabolic processGO:00602554210.076
Human
negative regulation of vulval developmentGO:00400272060.076
vesicle mediated transportGO:00161928520.075
regulation of signalingGO:00230511720.075
Human
digestive system developmentGO:00551231220.074
reproductive structure developmentGO:00486088500.072
chemotaxisGO:00069351200.071
regulation of cell communicationGO:00106461760.069
Human
neurogenesisGO:00220082360.069
multicellular organismal reproductive processGO:00486098150.068
lipid storageGO:00199155650.068
negative regulation of multicellular organismal processGO:00512412360.068
organelle organizationGO:00069967830.066
cell divisionGO:00513012620.066
response to unfolded proteinGO:0006986710.066
maintenance of locationGO:00512355800.065
negative regulation of cellular processGO:00485232390.063
negative regulation of developmental processGO:00510932270.062
regulation of signal transductionGO:00099661350.062
Human
mating behaviorGO:0007617320.061
body morphogenesisGO:00101716200.061
developmental growthGO:00485894120.060
gamete generationGO:00072764610.059
heterocycle biosynthetic processGO:00181301870.058
regulation of vulval developmentGO:00400282480.058
cell morphogenesisGO:00009021630.057
Zebrafish
determination of adult lifespanGO:00083408120.056
positive regulation of developmental growthGO:00486393540.055
vulval developmentGO:00400253330.055
positive regulation of multicellular organism growthGO:00400183520.054
regulation of multicellular organism growthGO:00400143730.054
lipid localizationGO:00108765730.053
regulation of primary metabolic processGO:00800902920.053
Human
protein localizationGO:00081042050.053
Human
multicellular organismal agingGO:00102598120.053
development of primary sexual characteristicsGO:00451378400.052
cellular nitrogen compound biosynthetic processGO:00442711920.052
regulation of epithelial cell proliferationGO:005067810.052
receptor mediated endocytosisGO:00068987150.051
regulation of cell cycleGO:00517261940.051
positive regulation of biosynthetic processGO:00098911090.050
protein metabolic processGO:00195384220.050
Human
positive regulation of cell cycleGO:0045787550.050
positive regulation of transcription dna templatedGO:00458931020.050
regulation of biosynthetic processGO:00098891890.049
Human
cell cycleGO:00070495260.049
gonad developmentGO:00084068400.049
positive regulation of macromolecule biosynthetic processGO:00105571090.048
single organism localizationGO:19025785180.048
Human
transcription from rna polymerase ii promoterGO:00063661490.048
rna biosynthetic processGO:00327741690.048
sensory organ morphogenesisGO:009059620.048
response to topologically incorrect proteinGO:0035966820.047
cellular process involved in reproduction in multicellular organismGO:00224123510.047
negative regulation of nematode larval developmentGO:00610642080.046
positive regulation of cellular processGO:00485223320.046
Human
response to endoplasmic reticulum stressGO:0034976710.043
positive regulation of cellular biosynthetic processGO:00313281090.043
transcription dna templatedGO:00063511680.043
regulation of developmental growthGO:00486383890.042
nucleobase containing compound biosynthetic processGO:00346541840.042
positive regulation of rna metabolic processGO:00512541030.041
post embryonic organ developmentGO:00485693360.040
biosynthetic processGO:00090583230.040
regulation of cell cycle processGO:00105641450.039
cell deathGO:00082195470.039
regulation of response to stimulusGO:00485832430.039
Human
regulation of cellular component organizationGO:00511282480.039
cellular component biogenesisGO:00440852970.038
embryonic morphogenesisGO:00485981520.038
negative regulation of macromolecule metabolic processGO:00106052290.038
agingGO:00075688120.038
positive regulation of growthGO:00459273690.037
nucleic acid templated transcriptionGO:00976591690.037
cell proliferationGO:00082831160.037
Fly
regulation of rna metabolic processGO:00512521730.036
Human
tube developmentGO:00352951260.036
regulation of transcription from rna polymerase ii promoterGO:00063571450.035
regulation of nucleic acid templated transcriptionGO:19035061650.035
Human
catabolic processGO:00090563180.034
negative regulation of cellular biosynthetic processGO:0031327650.034
regulation of cell differentiationGO:0045595810.033
generation of neuronsGO:00486992350.033
organelle fissionGO:00482853630.033
regulation of nucleobase containing compound metabolic processGO:00192192220.032
Human
cellular component assemblyGO:00226072930.032
single organism organelle organizationGO:19025895010.032
organelle assemblyGO:00709252140.031
oogenesisGO:00484772290.031
head developmentGO:006032210.031
regulation of cell proliferationGO:00421271050.031
Fly
negative regulation of metabolic processGO:00098922400.030
growthGO:00400075620.030
deathGO:00162655470.030
negative regulation of gene expressionGO:00106292170.030
negative regulation of biosynthetic processGO:0009890650.029
regulation of protein metabolic processGO:0051246810.029
Human
molting cycleGO:00423032810.029
digestive tract developmentGO:00485651220.029
programmed cell deathGO:00125015000.029
positive regulation of neuron projection developmentGO:001097640.029
multicellular organism growthGO:00352643850.028
negative regulation of macromolecule biosynthetic processGO:0010558650.028
germ cell developmentGO:00072813510.027
reproductive system developmentGO:00614588500.027
regulation of growthGO:00400084090.027
regulation of rna biosynthetic processGO:20011411650.027
Human
inductive cell migrationGO:00400391450.027
muscle structure developmentGO:00610611910.027
regulation of locomotionGO:00400121610.027
regulation of cellular metabolic processGO:00313233050.027
Human
positive regulation of nitrogen compound metabolic processGO:00511731340.026
negative regulation of response to stimulusGO:0048585730.026
macromolecular complex assemblyGO:00650031930.026
synaptic vesicle recyclingGO:003646530.026
macromolecular complex subunit organizationGO:00439333200.026
positive regulation of metabolic processGO:00098931870.025
Human
regulation of apoptotic signaling pathwayGO:200123310.025
response to organic substanceGO:00100331310.025
axon developmentGO:00615641630.024
positive regulation of nucleobase containing compound metabolic processGO:00459351340.024
single organism cellular localizationGO:1902580720.024
Human
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.023
matingGO:0007618340.023
oocyte axis specificationGO:000730920.023
single organism transportGO:00447654470.023
Human
organic cyclic compound biosynthetic processGO:19013621950.023
regulation of cytoplasmic transportGO:190364930.022
Human
neuron recognitionGO:0008038830.022
aromatic compound biosynthetic processGO:00194381920.022
positive regulation of neuron differentiationGO:004566640.022
canonical wnt signaling pathwayGO:006007030.021
microtubule based processGO:00070171820.021
intracellular transportGO:0046907770.020
Human
cellular response to unfolded proteinGO:0034620710.020
signal transductionGO:00071653170.020
Human
regulation of transcription dna templatedGO:00063551640.020
muscle tissue developmentGO:006053710.020
positive regulation of cell projection organizationGO:003134640.020
epithelial cell proliferationGO:005067310.020
mrna metabolic processGO:0016071310.020
female gamete generationGO:00072922540.020
mesodermal cell migrationGO:000807890.020
regulation of cell deathGO:0010941650.019
ras protein signal transductionGO:0007265310.019
small molecule metabolic processGO:00442811860.019
positive regulation of cellular metabolic processGO:00313251780.019
Human
anatomical structure formation involved in morphogenesisGO:00486462500.018
positive regulation of response to stimulusGO:0048584550.018
Human
neuron projection morphogenesisGO:00488121140.018
Zebrafish
positive regulation of rna biosynthetic processGO:19026801020.018
positive regulation of signalingGO:0023056660.018
Human
single organism intracellular transportGO:1902582700.018
Human
vesicle localizationGO:0051648240.018
negative regulation of nitrogen compound metabolic processGO:0051172630.018
regulation of mitotic cell cycleGO:0007346760.018
regulation of metabolic processGO:00192224780.018
Human
synaptic vesicle endocytosisGO:004848830.018
response to external stimulusGO:00096052890.017
epithelium developmentGO:0060429680.017
myofibril assemblyGO:00302391540.017
cell cycle switching mitotic to meiotic cell cycleGO:0051728350.017
ribonucleoprotein complex assemblyGO:002261840.017
cytoskeleton organizationGO:00070103390.017
oocyte developmentGO:0048599440.016
axon guidanceGO:0007411820.016
cellular macromolecule catabolic processGO:0044265730.016
muscle cell differentiationGO:00426921710.016
regulation of neuron differentiationGO:0045664400.016
oocyte constructionGO:000730820.016
positive regulation of nucleic acid templated transcriptionGO:19035081020.016
taxisGO:00423301280.016
ovipositionGO:00189913640.016
cell recognitionGO:0008037850.016
intracellular receptor signaling pathwayGO:003052220.016
synaptic vesicle localizationGO:0097479220.015
cellular response to topologically incorrect proteinGO:0035967760.015
positive regulation of neurogenesisGO:005076940.015
oocyte differentiationGO:0009994450.015
neurological system processGO:0050877530.015
negative regulation of translationGO:0017148100.015
protein modification processGO:00362112070.015
Human
skeletal muscle organ developmentGO:006053830.015
developmental maturationGO:0021700260.015
negative regulation of cell cycleGO:0045786530.015
regulation of organelle organizationGO:00330431640.014
regulation of cell developmentGO:0060284490.014
negative regulation of neurogenesisGO:005076840.014
regulation of transportGO:0051049910.014
Human
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.014
cellular localizationGO:00516413600.014
Human
mitotic cell cycle processGO:19030471940.014
response to abiotic stimulusGO:00096281520.014
er nucleus signaling pathwayGO:0006984660.014
asymmetric cell divisionGO:0008356360.013
establishment of localization in cellGO:00516493180.013
Human
positive regulation of cell morphogenesis involved in differentiationGO:001077040.013
cellular protein localizationGO:0034613750.013
Human
actomyosin structure organizationGO:00310321540.013
organic cyclic compound catabolic processGO:19013611190.013
positive regulation of jnk cascadeGO:004633030.013
organ morphogenesisGO:0009887670.013
regulation of neurogenesisGO:0050767400.013
regulation of cell projection organizationGO:0031344380.013
tissue developmentGO:00098881120.013
mitotic nuclear divisionGO:0007067890.013
epithelial tube morphogenesisGO:006056210.013
regulation of cellular component movementGO:0051270620.013
regulation of stem cell differentiationGO:200073610.013
negative regulation of signal transductionGO:0009968600.013
organic substance transportGO:00717021130.013
Human
intraspecies interaction between organismsGO:005170330.013
regulation of intracellular signal transductionGO:1902531770.013
dendrite developmentGO:0016358420.013
Zebrafish
endoplasmic reticulum unfolded protein responseGO:0030968660.012
innate immune responseGO:00450871900.012
regulation of cell divisionGO:00513021420.012
organic substance catabolic processGO:19015752940.012
cellular response to abiotic stimulusGO:007121440.012
translationGO:0006412370.012
dauer larval developmentGO:0040024920.012
cellular component assembly involved in morphogenesisGO:00109271830.012
regulation of nucleocytoplasmic transportGO:004682230.012
Human
male sex differentiationGO:0046661860.012
male mating behaviorGO:0060179260.012
neuromuscular junction developmentGO:000752820.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
positive regulation of signal transductionGO:0009967400.012
Human
cellular macromolecular complex assemblyGO:00346221840.012
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051250.012
necrotic cell deathGO:0070265290.012
macromolecule catabolic processGO:00090572020.011
tube morphogenesisGO:0035239790.011
negative regulation of cell communicationGO:0010648610.011
negative regulation of nucleic acid templated transcriptionGO:1903507530.011
negative regulation of wnt signaling pathwayGO:003017860.011
pattern specification processGO:0007389590.011
rna splicing via transesterification reactionsGO:000037580.011
myosin filament organizationGO:00310331380.011
spindle organizationGO:0007051920.011
muscle cell developmentGO:00550011580.011
neuromuscular processGO:005090510.011
negative regulation of cellular metabolic processGO:0031324950.011
cellular protein complex assemblyGO:00436231780.011
regulation of small gtpase mediated signal transductionGO:0051056410.011
collagen and cuticulin based cuticle developmentGO:0040002990.011
defense responseGO:00069522960.010
regulation of cellular protein metabolic processGO:0032268750.010
Human
striated muscle cell developmentGO:00550021570.010
molting cycle collagen and cuticulin based cuticleGO:00189962810.010
cellular response to stressGO:00335541620.010
regulation of nervous system developmentGO:0051960410.010
regulation of meiotic cell cycleGO:00514451360.010

mec-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011