Caenorhabditis elegans

100 known processes

pxn-2 (CELE_K09C8.5)

Protein PXN-2

pxn-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.590
Worm
embryo developmentGO:000979030520.580
locomotionGO:004001116340.442
post embryonic developmentGO:000979121520.370
Worm
transportGO:000681010930.230
Fly
axon developmentGO:00615641630.222
single organism localizationGO:19025785180.178
Fly
genitalia developmentGO:00488067410.178
regulation of developmental processGO:00507936840.176
cell migrationGO:00164773060.171
muscle tissue developmentGO:006053710.157
muscle cell differentiationGO:00426921710.142
development of primary sexual characteristicsGO:00451378400.137
growthGO:00400075620.136
cell developmentGO:00484686960.133
establishment of localizationGO:005123411710.128
Fly
organelle organizationGO:00069967830.123
developmental process involved in reproductionGO:000300611650.120
single organism organelle organizationGO:19025895010.119
single organism reproductive processGO:004470211960.113
cell motilityGO:00488703130.112
cellular component movementGO:00069283880.112
reproductive system developmentGO:00614588500.111
regulation of multicellular organismal processGO:00512397260.110
localization of cellGO:00516743130.109
body morphogenesisGO:00101716200.107
developmental growthGO:00485894120.106
gonad developmentGO:00084068400.105
agingGO:00075688120.104
neuron differentiationGO:00301822170.104
regulation of biological qualityGO:00650087410.103
cell morphogenesis involved in neuron differentiationGO:00486671110.098
organ developmentGO:004851311020.097
macromolecule localizationGO:00330367710.094
multicellular organismal agingGO:00102598120.093
vesicle mediated transportGO:00161928520.089
Fly
determination of adult lifespanGO:00083408120.089
positive regulation of multicellular organism growthGO:00400183520.084
regulation of developmental growthGO:00486383890.083
response to chemicalGO:00422213560.083
regulation of multicellular organismal developmentGO:20000263170.082
regulation of growthGO:00400084090.081
positive regulation of locomotionGO:0040017420.081
organelle assemblyGO:00709252140.080
hermaphrodite genitalia developmentGO:00400357340.079
protein complex biogenesisGO:00702711860.079
anatomical structure formation involved in morphogenesisGO:00486462500.079
reproductive structure developmentGO:00486088500.079
multicellular organism growthGO:00352643850.078
endocytosisGO:00068978190.078
Fly
positive regulation of developmental processGO:00510944080.077
cell deathGO:00082195470.076
cellular component biogenesisGO:00440852970.076
cell projection organizationGO:00300302310.076
organelle fissionGO:00482853630.075
negative regulation of multicellular organismal processGO:00512412360.075
receptor mediated endocytosisGO:00068987150.075
muscle structure developmentGO:00610611910.075
regulation of multicellular organism growthGO:00400143730.073
meiotic nuclear divisionGO:00071263000.072
meiotic cell cycleGO:00513213350.072
cellular macromolecular complex assemblyGO:00346221840.070
neuron projection guidanceGO:0097485820.069
maintenance of locationGO:00512355800.068
macromolecular complex subunit organizationGO:00439333200.068
positive regulation of multicellular organismal processGO:00512404170.068
sex differentiationGO:00075489090.068
axon guidanceGO:0007411820.067
regulation of locomotionGO:00400121610.067
actin cytoskeleton organizationGO:00300361840.066
lipid localizationGO:00108765730.066
neurogenesisGO:00220082360.066
protein complex subunit organizationGO:00718222800.066
actomyosin structure organizationGO:00310321540.065
myofibril assemblyGO:00302391540.064
cellular protein complex assemblyGO:00436231780.062
lipid storageGO:00199155650.061
protein complex assemblyGO:00064611860.061
secretionGO:00469031470.060
cellular component assembly involved in morphogenesisGO:00109271830.059
digestive tract morphogenesisGO:0048546760.058
striated muscle cell differentiationGO:00511461580.058
neuron developmentGO:00486661990.055
cellular component assemblyGO:00226072930.054
cellular biosynthetic processGO:00442493150.053
positive regulation of growthGO:00459273690.052
cytoskeleton organizationGO:00070103390.052
muscle cell developmentGO:00550011580.052
single organism transportGO:00447654470.050
Fly
generation of neuronsGO:00486992350.050
striated muscle myosin thick filament assemblyGO:00716881380.049
skeletal muscle organ developmentGO:006053830.049
behaviorGO:00076105270.048
cell projection morphogenesisGO:00488581480.047
tube morphogenesisGO:0035239790.046
nucleobase containing compound metabolic processGO:00061394060.046
cellular component morphogenesisGO:00329893180.046
myosin filament assemblyGO:00310341380.044
establishment of localization in cellGO:00516493180.043
actin filament based processGO:00300291910.042
striated muscle cell developmentGO:00550021570.042
sexual reproductionGO:00199535460.042
macromolecule biosynthetic processGO:00090592500.042
multi organism reproductive processGO:00447038670.042
positive regulation of developmental growthGO:00486393540.041
basement membrane organizationGO:007171130.041
muscle attachmentGO:001620330.039
organ morphogenesisGO:0009887670.039
protein localizationGO:00081042050.038
signalingGO:00230524010.037
muscle organ morphogenesisGO:004864440.037
inductive cell migrationGO:00400391450.037
system processGO:00030081360.037
cell part morphogenesisGO:00329901520.037
signal transductionGO:00071653170.036
response to external stimulusGO:00096052890.036
multicellular organismal reproductive processGO:00486098150.035
tissue developmentGO:00098881120.035
nervous system developmentGO:00073992530.033
chemotaxisGO:00069351200.033
cell substrate adhesionGO:003158910.033
response to woundingGO:000961140.033
cell recognitionGO:0008037850.032
programmed cell deathGO:00125015000.032
biosynthetic processGO:00090583230.032
regulation of localizationGO:00328791940.032
small molecule metabolic processGO:00442811860.031
phosphorus metabolic processGO:00067932320.031
apoptotic processGO:00069154780.031
cellular macromolecule biosynthetic processGO:00346452470.031
ovipositionGO:00189913640.031
cellular localizationGO:00516413600.031
secretion by cellGO:00329401380.030
regulation of cellular component organizationGO:00511282480.030
macromolecular complex assemblyGO:00650031930.029
transcription dna templatedGO:00063511680.029
microtubule based processGO:00070171820.029
regulation of striated muscle contractionGO:000694240.028
organic substance catabolic processGO:19015752940.028
regulation of macromolecule metabolic processGO:00602554210.028
negative regulation of developmental processGO:00510932270.028
neuron projection morphogenesisGO:00488121140.028
deathGO:00162655470.028
myosin filament organizationGO:00310331380.028
vulval developmentGO:00400253330.027
nucleobase containing small molecule metabolic processGO:00550861150.027
embryonic morphogenesisGO:00485981520.027
cellular protein metabolic processGO:00442672790.027
Worm
single organism signalingGO:00447004010.027
neuron projection developmentGO:00311751870.026
digestive tract developmentGO:00485651220.026
single organism catabolic processGO:00447121290.025
Human
negative regulation of biological processGO:00485195670.025
protein metabolic processGO:00195384220.025
Worm
epithelial tube morphogenesisGO:006056210.025
reproductive behaviorGO:00190983870.025
heterocycle biosynthetic processGO:00181301870.025
aromatic compound biosynthetic processGO:00194381920.025
ion transmembrane transportGO:0034220910.025
taxisGO:00423301280.024
cell divisionGO:00513012620.024
regulation of rna biosynthetic processGO:20011411650.024
organonitrogen compound metabolic processGO:19015641510.024
regulation of cell cycle processGO:00105641450.023
cell cycleGO:00070495260.023
organic substance biosynthetic processGO:19015763230.023
cellular catabolic processGO:00442481990.023
Human
muscle organ developmentGO:0007517260.023
response to acid chemicalGO:000110140.023
heterocycle catabolic processGO:00467001190.023
axonal defasciculationGO:000741410.023
nucleic acid templated transcriptionGO:00976591690.022
gene expressionGO:00104674120.022
neuromuscular junction developmentGO:000752820.022
regulation of nuclear divisionGO:00517831150.022
post embryonic organ developmentGO:00485693360.022
digestive system developmentGO:00551231220.022
cell morphogenesis involved in differentiationGO:00009041120.022
muscle system processGO:0003012430.022
positive regulation of cellular processGO:00485223320.022
protein catabolic processGO:00301631620.021
negative regulation of cellular component organizationGO:0051129330.021
organic substance transportGO:00717021130.021
organic cyclic compound catabolic processGO:19013611190.021
chromosome organizationGO:00512761040.021
regulation of meiosisGO:0040020940.021
ion transportGO:00068111130.021
regulation of nitrogen compound metabolic processGO:00511712220.020
regulation of cell divisionGO:00513021420.020
germ cell developmentGO:00072813510.020
phosphate containing compound metabolic processGO:00067962320.020
multi multicellular organism processGO:00447063900.020
regulation of post embryonic developmentGO:00485802600.020
negative regulation of cellular processGO:00485232390.020
regulation of meiotic cell cycleGO:00514451360.020
axonal fasciculationGO:0007413790.020
regulation of gene expression epigeneticGO:00400291630.020
nucleic acid metabolic processGO:00903042990.020
cell surface receptor signaling pathwayGO:00071661490.019
chromosome segregationGO:00070591800.019
posttranscriptional regulation of gene expressionGO:00106081660.019
regulation of gene expressionGO:00104683660.019
head developmentGO:006032210.019
molting cycleGO:00423032810.019
Worm
transcription from rna polymerase ii promoterGO:00063661490.019
molting cycle collagen and cuticulin based cuticleGO:00189962810.019
Worm
nucleobase containing compound biosynthetic processGO:00346541840.019
negative regulation of nematode larval developmentGO:00610642080.019
cell cycle processGO:00224024820.019
axonogenesisGO:00074091020.019
regulation of nematode larval developmentGO:00610622600.019
regulation of organelle organizationGO:00330431640.019
gene silencingGO:00164581430.018
multicellular organism reproductionGO:00325048190.018
carbohydrate derivative metabolic processGO:19011351410.018
negative regulation of post embryonic developmentGO:00485812080.018
positive regulation of cell migrationGO:003033530.018
organic acid metabolic processGO:0006082470.018
gamete generationGO:00072764610.018
protein phosphorylationGO:0006468850.017
gastrulationGO:0007369580.017
cilium assemblyGO:0042384280.017
response to abiotic stimulusGO:00096281520.017
developmental growth involved in morphogenesisGO:0060560370.017
regulation of vulval developmentGO:00400282480.017
protein oligomerizationGO:005125940.017
nucleoside phosphate metabolic processGO:00067531080.017
cellular nitrogen compound biosynthetic processGO:00442711920.017
catabolic processGO:00090563180.016
Human
excretionGO:0007588490.016
regulation of cellular metabolic processGO:00313233050.016
regulation of cellular macromolecule biosynthetic processGO:20001121880.016
synapse organizationGO:0050808240.016
cellular nitrogen compound catabolic processGO:00442701190.016
regulation of cell communicationGO:00106461760.016
multicellular organismal reproductive behaviorGO:00330573840.016
tissue morphogenesisGO:0048729650.016
negative regulation of metabolic processGO:00098922400.016
cilium organizationGO:0044782320.016
regulation of metabolic processGO:00192224780.016
carboxylic acid metabolic processGO:0019752340.016
cellular protein modification processGO:00064642070.016
Worm
regulation of cell proliferationGO:00421271050.015
neuron projection extensionGO:1990138370.015
regulation of anatomical structure sizeGO:0090066460.015
ribonucleoside metabolic processGO:0009119980.015
neuron recognitionGO:0008038830.015
cell cell signalingGO:00072671180.015
organic cyclic compound biosynthetic processGO:19013621950.015
purine nucleotide metabolic processGO:0006163950.015
embryonic body morphogenesisGO:0010172490.015
organonitrogen compound catabolic processGO:1901565900.015
synaptic transmissionGO:00072681060.015
epithelium developmentGO:0060429680.015
nucleobase containing compound catabolic processGO:00346551140.014
oxoacid metabolic processGO:0043436470.014
sensory organ morphogenesisGO:009059620.014
cell proliferationGO:00082831160.014
regulation of cellular component movementGO:0051270620.014
axon extensionGO:0048675370.014
regulation of cellular ketone metabolic processGO:001056530.014
negative regulation of gene expression epigeneticGO:004581420.014
multi organism reproductive behaviorGO:00447053870.014
macromolecule modificationGO:00434122180.014
Worm
cellular process involved in reproduction in multicellular organismGO:00224123510.014
regulation of biosynthetic processGO:00098891890.014
anion transportGO:0006820300.014
nucleoside metabolic processGO:0009116990.014
purine nucleotide catabolic processGO:0006195750.013
cell morphogenesisGO:00009021630.013
tube developmentGO:00352951260.013
posttranscriptional gene silencing by rnaGO:00351941430.013
regulation of cell differentiationGO:0045595810.013
pharyngeal pumpingGO:0043050580.013
ribonucleotide metabolic processGO:0009259990.013
regulation of transcription dna templatedGO:00063551640.013
purine ribonucleoside metabolic processGO:0046128920.013
regulation of transcription from rna polymerase ii promoterGO:00063571450.013
transmembrane transportGO:00550851100.013
regulation of nucleic acid templated transcriptionGO:19035061650.013
carbohydrate derivative catabolic processGO:1901136820.013
amine catabolic processGO:000931010.013
calcium mediated signalingGO:001972230.013
membrane organizationGO:00610241350.013
regulation of cellular amine metabolic processGO:003323800.013
rna interferenceGO:00162461370.013
nucleotide metabolic processGO:00091171080.013
glycosyl compound metabolic processGO:19016571000.012
rna localizationGO:000640330.012
organic acid biosynthetic processGO:0016053210.012
organophosphate metabolic processGO:00196371250.012
purine ribonucleoside catabolic processGO:0046130750.012
cellular homeostasisGO:0019725220.012
cellular response to stressGO:00335541620.012
negative regulation of vulval developmentGO:00400272060.012
negative regulation of macromolecule metabolic processGO:00106052290.012
regulation of cell migrationGO:0030334550.012
rna biosynthetic processGO:00327741690.012
gene silencing by rnaGO:00310471430.012
regulation of cell motilityGO:2000145570.012
defense responseGO:00069522960.012
cell fate commitmentGO:00451651390.012
single organism biosynthetic processGO:0044711910.012
cellular amine metabolic processGO:0044106150.012
mitotic sister chromatid segregationGO:0000070380.012
regulation of apoptotic signaling pathwayGO:200123310.012
purine nucleoside metabolic processGO:0042278920.012
adult locomotory behaviorGO:000834410.012
anion transmembrane transportGO:0098656210.012
cell matrix adhesionGO:000716010.012
fertilizationGO:0009566630.012
cellular amino acid metabolic processGO:0006520150.012
chemosensory behaviorGO:0007635330.012
positive regulation of striated muscle contractionGO:004598920.012
adult behaviorGO:003053430.012
eating behaviorGO:0042755590.011
mitotic nuclear divisionGO:0007067890.011
muscle fiber developmentGO:004874720.011
negative regulation of signal transductionGO:0009968600.011
organelle localizationGO:00516401270.011
regulation of synapse assemblyGO:005196320.011
regulation of cell cycleGO:00517261940.011
purine containing compound metabolic processGO:0072521950.011
regulation of ion transportGO:0043269390.011
negative regulation of signalingGO:0023057610.011
developmental cell growthGO:0048588390.011
regulation of signal transductionGO:00099661350.011
regulation of cellular biosynthetic processGO:00313261890.011
cilium morphogenesisGO:0060271330.011
cgmp metabolic processGO:004606820.011
protein modification processGO:00362112070.011
Worm
posttranscriptional gene silencingGO:00164411430.011
multi organism behaviorGO:00517053890.011
bmp signaling pathwayGO:003050930.010
ribose phosphate metabolic processGO:0019693990.010
cellular response to chemical stimulusGO:00708871290.010
Human
regulation of muscle system processGO:0090257200.010
feeding behaviorGO:0007631700.010
meiotic chromosome segregationGO:00451321390.010
cell type specific apoptotic processGO:009728540.010
synaptic growth at neuromuscular junctionGO:005112410.010
establishment or maintenance of cell polarityGO:0007163630.010
amine metabolic processGO:0009308150.010
establishment of protein localization to membraneGO:009015030.010
muscle contractionGO:0006936430.010

pxn-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
musculoskeletal system diseaseDOID:1700.044
myopathyDOID:42300.044
muscular diseaseDOID:008000000.044
muscle tissue diseaseDOID:6600.044
congenital muscular dystrophyDOID:005055700.025
muscular dystrophyDOID:988400.025
heart diseaseDOID:11400.017
intrinsic cardiomyopathyDOID:006003600.017
cardiomyopathyDOID:005070000.017
cardiovascular system diseaseDOID:128700.017
dilated cardiomyopathyDOID:1293000.016
nervous system diseaseDOID:86300.014