Caenorhabditis elegans

43 known processes

tbx-2 (CELE_F21H11.3)

Protein TBX-2

tbx-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.795
Zebrafish Mouse Worm
embryo developmentGO:000979030520.724
Zebrafish Mouse Worm
locomotionGO:004001116340.484
organelle organizationGO:00069967830.354
cell part morphogenesisGO:00329901520.352
regulation of multicellular organismal processGO:00512397260.309
Zebrafish Mouse
developmental process involved in reproductionGO:000300611650.278
Worm
regulation of nitrogen compound metabolic processGO:00511712220.275
Mouse Worm Fly
multicellular organismal reproductive processGO:00486098150.274
cellular component movementGO:00069283880.271
Zebrafish
response to chemicalGO:00422213560.271
transportGO:000681010930.262
gamete generationGO:00072764610.259
multicellular organism reproductionGO:00325048190.258
gene expressionGO:00104674120.252
Mouse Worm Fly
establishment of localizationGO:005123411710.250
single organism reproductive processGO:004470211960.249
cell deathGO:00082195470.243
Worm
regulation of cellular macromolecule biosynthetic processGO:20001121880.238
Mouse Worm Fly
regulation of macromolecule metabolic processGO:00602554210.221
Mouse Worm Fly
axonogenesisGO:00074091020.214
ovipositionGO:00189913640.191
neuron projection developmentGO:00311751870.190
Worm
cell projection organizationGO:00300302310.181
Worm
organ developmentGO:004851311020.177
hermaphrodite genitalia developmentGO:00400357340.172
cell morphogenesisGO:00009021630.172
nucleobase containing compound metabolic processGO:00061394060.171
Mouse Worm Fly
generation of neuronsGO:00486992350.171
Zebrafish Worm
development of primary sexual characteristicsGO:00451378400.171
gonad developmentGO:00084068400.171
regulation of nucleobase containing compound metabolic processGO:00192192220.170
Mouse Worm Fly
regulation of metabolic processGO:00192224780.169
Mouse Worm Fly
vesicle mediated transportGO:00161928520.169
sex differentiationGO:00075489090.165
Worm
heterocycle biosynthetic processGO:00181301870.164
Mouse Worm Fly
multi organism behaviorGO:00517053890.162
reproductive structure developmentGO:00486088500.162
cell motilityGO:00488703130.161
Zebrafish
head developmentGO:006032210.161
Zebrafish Mouse
programmed cell deathGO:00125015000.158
Worm
multicellular organismal reproductive behaviorGO:00330573840.158
endocytosisGO:00068978190.157
multi organism reproductive processGO:00447038670.152
post embryonic developmentGO:000979121520.150
determination of adult lifespanGO:00083408120.148
reproductive system developmentGO:00614588500.147
cell developmentGO:00484686960.146
Zebrafish Mouse Worm
rna biosynthetic processGO:00327741690.142
Mouse Worm Fly
nervous system developmentGO:00073992530.141
Zebrafish Mouse Worm
cell projection morphogenesisGO:00488581480.137
cellular localizationGO:00516413600.134
behaviorGO:00076105270.130
macromolecule localizationGO:00330367710.130
regulation of post embryonic developmentGO:00485802600.125
cellular macromolecule biosynthetic processGO:00346452470.122
Mouse Worm Fly
embryonic morphogenesisGO:00485981520.121
Zebrafish Mouse Worm
regulation of multicellular organismal developmentGO:20000263170.121
Mouse
positive regulation of rna metabolic processGO:00512541030.120
Mouse Worm
protein localizationGO:00081042050.120
biosynthetic processGO:00090583230.116
Mouse Worm Fly
single organism organelle organizationGO:19025895010.115
protein complex subunit organizationGO:00718222800.113
positive regulation of rna biosynthetic processGO:19026801020.113
Mouse Worm
cell fate commitmentGO:00451651390.112
regulation of primary metabolic processGO:00800902920.112
Mouse Worm Fly
sexual reproductionGO:00199535460.110
regulation of neuron differentiationGO:0045664400.110
deathGO:00162655470.103
Worm
positive regulation of metabolic processGO:00098931870.101
Mouse Worm
cellular biosynthetic processGO:00442493150.100
Mouse Worm Fly
positive regulation of nitrogen compound metabolic processGO:00511731340.100
Mouse Worm
negative regulation of macromolecule biosynthetic processGO:0010558650.099
Mouse Fly
regulation of developmental processGO:00507936840.097
Mouse
anatomical structure formation involved in morphogenesisGO:00486462500.097
Mouse Worm
apoptotic processGO:00069154780.096
Worm
positive regulation of macromolecule metabolic processGO:00106041490.095
Mouse Worm
regulation of biological qualityGO:00650087410.094
organelle fissionGO:00482853630.094
single organism localizationGO:19025785180.093
multicellular organismal agingGO:00102598120.093
regulation of rna biosynthetic processGO:20011411650.093
Mouse Worm Fly
regulation of rna metabolic processGO:00512521730.091
Mouse Worm Fly
cell cycleGO:00070495260.091
response to external stimulusGO:00096052890.090
negative regulation of cellular processGO:00485232390.090
Mouse Fly
cytoskeleton organizationGO:00070103390.089
regulation of nematode larval developmentGO:00610622600.089
genitalia developmentGO:00488067410.088
multi organism reproductive behaviorGO:00447053870.087
regulation of cellular metabolic processGO:00313233050.086
Mouse Worm Fly
reproductive behaviorGO:00190983870.086
body morphogenesisGO:00101716200.086
Worm
male sex differentiationGO:0046661860.085
Worm
signalingGO:00230524010.085
neurogenesisGO:00220082360.084
Zebrafish Worm
cellular component morphogenesisGO:00329893180.083
germ cell developmentGO:00072813510.083
regulation of gene expressionGO:00104683660.082
Mouse Worm Fly
chemotaxisGO:00069351200.082
positive regulation of nucleobase containing compound metabolic processGO:00459351340.082
Mouse Worm
regulation of macromolecule biosynthetic processGO:00105561890.082
Mouse Worm Fly
digestive tract developmentGO:00485651220.082
single organism transportGO:00447654470.081
chromosome segregationGO:00070591800.080
regulation of signal transductionGO:00099661350.079
negative regulation of gene expressionGO:00106292170.079
Mouse Fly
rna metabolic processGO:00160702280.079
Mouse Worm Fly
regulation of biosynthetic processGO:00098891890.078
Mouse Worm Fly
microtubule based processGO:00070171820.077
aromatic compound biosynthetic processGO:00194381920.074
Mouse Worm Fly
female gamete generationGO:00072922540.073
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.072
Mouse Fly
tube morphogenesisGO:0035239790.071
Zebrafish Mouse Worm
nematode male tail tip morphogenesisGO:0045138770.070
Worm
cell morphogenesis involved in differentiationGO:00009041120.070
negative regulation of biosynthetic processGO:0009890650.070
Mouse Fly
cellular process involved in reproduction in multicellular organismGO:00224123510.070
meiotic nuclear divisionGO:00071263000.066
maintenance of locationGO:00512355800.066
lipid storageGO:00199155650.065
cellular component assemblyGO:00226072930.064
regulation of cell communicationGO:00106461760.064
axon developmentGO:00615641630.064
Worm
neuron developmentGO:00486661990.064
Zebrafish Worm
cellular component biogenesisGO:00440852970.063
axon guidanceGO:0007411820.063
multi multicellular organism processGO:00447063900.063
lipid localizationGO:00108765730.062
regulation of developmental growthGO:00486383890.061
Mouse
regulation of response to stimulusGO:00485832430.061
macromolecule biosynthetic processGO:00090592500.061
Mouse Worm Fly
positive regulation of multicellular organismal processGO:00512404170.061
Mouse
organic substance biosynthetic processGO:19015763230.060
Mouse Worm Fly
agingGO:00075688120.060
Mouse
actin filament based processGO:00300291910.059
regulation of multicellular organism growthGO:00400143730.059
neuron differentiationGO:00301822170.059
Zebrafish Worm
nucleic acid metabolic processGO:00903042990.058
Mouse Worm Fly
regulation of neurogenesisGO:0050767400.058
receptor mediated endocytosisGO:00068987150.056
negative regulation of nucleobase containing compound metabolic processGO:0045934630.056
Mouse Fly
negative regulation of biological processGO:00485195670.055
Mouse Fly
neuron projection guidanceGO:0097485820.054
positive regulation of cellular biosynthetic processGO:00313281090.054
Mouse Worm
regulation of transcription dna templatedGO:00063551640.052
Mouse Worm Fly
actin cytoskeleton organizationGO:00300361840.052
meiotic cell cycleGO:00513213350.052
cell morphogenesis involved in neuron differentiationGO:00486671110.052
cellular response to stressGO:00335541620.051
organelle assemblyGO:00709252140.051
phosphorus metabolic processGO:00067932320.051
regulation of cell cycleGO:00517261940.050
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.050
Worm
negative regulation of metabolic processGO:00098922400.049
Mouse Fly
regulation of cellular component sizeGO:0032535400.049
muscle tissue developmentGO:006053710.049
Mouse
organic cyclic compound biosynthetic processGO:19013621950.049
Mouse Worm Fly
cellular component assembly involved in morphogenesisGO:00109271830.048
regulation of locomotionGO:00400121610.048
taxisGO:00423301280.048
cuticle developmentGO:00423351000.048
localization of cellGO:00516743130.047
Zebrafish
nucleobase containing compound biosynthetic processGO:00346541840.047
Mouse Worm Fly
macromolecular complex assemblyGO:00650031930.047
neuron projection morphogenesisGO:00488121140.047
cellular macromolecular complex assemblyGO:00346221840.045
molting cycle collagen and cuticulin based cuticleGO:00189962810.045
microtubule based movementGO:0007018330.045
regulation of cellular biosynthetic processGO:00313261890.045
Mouse Worm Fly
cell cycle processGO:00224024820.044
growthGO:00400075620.044
Mouse Fly
transcription from rna polymerase ii promoterGO:00063661490.044
Mouse Worm Fly
pattern specification processGO:0007389590.044
Zebrafish Mouse Fly
cell divisionGO:00513012620.043
negative regulation of nucleic acid templated transcriptionGO:1903507530.043
Mouse Fly
positive regulation of nucleic acid templated transcriptionGO:19035081020.043
Mouse Worm
multicellular organism growthGO:00352643850.042
cell recognitionGO:0008037850.042
Worm
organonitrogen compound metabolic processGO:19015641510.042
molting cycleGO:00423032810.042
vulval developmentGO:00400253330.041
positive regulation of biosynthetic processGO:00098911090.041
Mouse Worm
positive regulation of developmental growthGO:00486393540.040
Mouse
regulation of vulval developmentGO:00400282480.040
negative regulation of rna biosynthetic processGO:1902679530.040
Mouse Fly
response to abiotic stimulusGO:00096281520.039
regulation of nucleic acid templated transcriptionGO:19035061650.039
Mouse Worm Fly
collagen and cuticulin based cuticle developmentGO:0040002990.038
negative regulation of nitrogen compound metabolic processGO:0051172630.038
Mouse Fly
negative regulation of multicellular organismal processGO:00512412360.038
Mouse
muscle structure developmentGO:00610611910.038
tube developmentGO:00352951260.037
regulation of synaptic transmissionGO:0050804340.037
spermatogenesisGO:0007283410.036
purine ribonucleoside metabolic processGO:0046128920.036
negative regulation of macromolecule metabolic processGO:00106052290.035
Mouse Fly
positive regulation of cellular metabolic processGO:00313251780.035
Mouse Worm
positive regulation of transcription dna templatedGO:00458931020.035
Mouse Worm
digestive system developmentGO:00551231220.035
regulation of cellular component organizationGO:00511282480.035
positive regulation of multicellular organism growthGO:00400183520.035
actomyosin structure organizationGO:00310321540.034
cell cell signalingGO:00072671180.034
tissue developmentGO:00098881120.033
Zebrafish Mouse Worm
regulation of cytoskeleton organizationGO:0051493410.033
single organism signalingGO:00447004010.033
purine ribonucleoside catabolic processGO:0046130750.033
organophosphate metabolic processGO:00196371250.033
macromolecular complex subunit organizationGO:00439333200.032
gtp metabolic processGO:0046039460.032
regulation of cell differentiationGO:0045595810.032
Mouse
developmental maturationGO:0021700260.032
positive regulation of cellular processGO:00485223320.032
Mouse Worm
developmental growthGO:00485894120.032
Mouse
protein metabolic processGO:00195384220.031
signal transductionGO:00071653170.031
positive regulation of developmental processGO:00510944080.031
Mouse
embryonic body morphogenesisGO:0010172490.031
Worm
cellular protein metabolic processGO:00442672790.031
small molecule metabolic processGO:00442811860.031
nucleic acid templated transcriptionGO:00976591690.030
Mouse Worm Fly
phosphorylationGO:00163101160.030
cellular protein complex assemblyGO:00436231780.030
nucleobase containing compound catabolic processGO:00346551140.030
organic cyclic compound catabolic processGO:19013611190.030
regulation of growthGO:00400084090.030
Mouse
male anatomical structure morphogenesisGO:0090598780.030
Worm
phosphate containing compound metabolic processGO:00067962320.030
protein complex biogenesisGO:00702711860.029
organophosphate catabolic processGO:0046434810.029
positive regulation of nucleoside metabolic processGO:0045979280.029
striated muscle cell developmentGO:00550021570.029
Mouse
regulation of nucleoside metabolic processGO:0009118370.029
striated muscle myosin thick filament assemblyGO:00716881380.029
regulation of organelle organizationGO:00330431640.029
catabolic processGO:00090563180.029
myofibril assemblyGO:00302391540.028
ovulationGO:0030728330.028
synaptic transmissionGO:00072681060.028
ribonucleoside triphosphate metabolic processGO:0009199870.028
oogenesisGO:00484772290.028
protein complex assemblyGO:00064611860.028
dendrite developmentGO:0016358420.028
establishment of localization in cellGO:00516493180.028
negative regulation of rna metabolic processGO:0051253530.028
Mouse Fly
regulation of mitotic cell cycleGO:0007346760.027
carbohydrate derivative metabolic processGO:19011351410.027
striated muscle cell differentiationGO:00511461580.027
Mouse
cytokinesisGO:0000910800.027
purine ribonucleoside triphosphate metabolic processGO:0009205870.027
heterocycle catabolic processGO:00467001190.026
epithelial tube morphogenesisGO:006056210.026
Zebrafish Mouse
cell migrationGO:00164773060.026
Zebrafish
tissue morphogenesisGO:0048729650.026
Zebrafish Mouse Worm
regulation of protein localizationGO:0032880500.026
negative regulation of cellular metabolic processGO:0031324950.026
Mouse Fly
neuron fate specificationGO:004866580.025
Zebrafish
gastrulationGO:0007369580.025
Zebrafish Worm
myosin filament assemblyGO:00310341380.025
negative regulation of cellular biosynthetic processGO:0031327650.025
Mouse Fly
immune responseGO:00069551920.024
positive regulation of macromolecule biosynthetic processGO:00105571090.024
Mouse Worm
amine metabolic processGO:0009308150.024
cellular catabolic processGO:00442481990.024
organonitrogen compound catabolic processGO:1901565900.024
positive regulation of synaptic transmissionGO:0050806240.023
purine ribonucleotide catabolic processGO:0009154750.023
purine nucleoside metabolic processGO:0042278920.023
negative regulation of cell communicationGO:0010648610.023
muscle cell differentiationGO:00426921710.023
single organism behaviorGO:0044708830.023
purine containing compound catabolic processGO:0072523750.022
regulation of cell divisionGO:00513021420.022
organic substance catabolic processGO:19015752940.022
positive regulation of growthGO:00459273690.022
Mouse
intracellular transportGO:0046907770.022
muscle cell developmentGO:00550011580.021
Mouse
negative regulation of signalingGO:0023057610.021
cell maturationGO:0048469260.021
digestive tract morphogenesisGO:0048546760.021
Zebrafish Worm
anterior posterior pattern specificationGO:0009952270.020
Fly
purine nucleoside catabolic processGO:0006152750.020
nucleoside catabolic processGO:0009164780.020
ribonucleotide metabolic processGO:0009259990.020
canonical wnt signaling pathwayGO:006007030.020
cellular nitrogen compound biosynthetic processGO:00442711920.020
Mouse Worm Fly
positive regulation of nucleotide catabolic processGO:0030813280.020
regulation of cell developmentGO:0060284490.020
posttranscriptional regulation of gene expressionGO:00106081660.019
organelle localizationGO:00516401270.019
positive regulation of neuron differentiationGO:004566640.019
negative regulation of developmental processGO:00510932270.019
Mouse
aromatic compound catabolic processGO:00194391160.019
regulation of nucleotide catabolic processGO:0030811350.019
intracellular signal transductionGO:0035556960.019
regenerationGO:003109940.019
glycosyl compound catabolic processGO:1901658790.019
membrane organizationGO:00610241350.019
regulation of anatomical structure morphogenesisGO:0022603510.019
Mouse
purine ribonucleotide metabolic processGO:0009150950.019
regulation of nervous system developmentGO:0051960410.018
cell type specific apoptotic processGO:009728540.018
post embryonic organ developmentGO:00485693360.018
Fly
regulation of cell cycle processGO:00105641450.018
myosin filament organizationGO:00310331380.018
mitotic cell cycle processGO:19030471940.018
meiotic cell cycle processGO:19030461700.017
meiotic chromosome segregationGO:00451321390.017
ribonucleotide catabolic processGO:0009261750.017
defense response to bacteriumGO:0042742860.017
negative regulation of response to stimulusGO:0048585730.017
transcription dna templatedGO:00063511680.017
Mouse Worm Fly
nucleobase containing small molecule metabolic processGO:00550861150.017
response to woundingGO:000961140.017
cellular macromolecule localizationGO:0070727750.016
carboxylic acid metabolic processGO:0019752340.016
regulation of signalingGO:00230511720.016
regulation of cellular amine metabolic processGO:003323800.016
nucleoside triphosphate metabolic processGO:0009141870.016
male gamete generationGO:0048232410.016
asymmetric protein localizationGO:0008105350.016
synaptic growth at neuromuscular junctionGO:005112410.016
regulation of cell deathGO:0010941650.016
purine nucleoside triphosphate catabolic processGO:0009146720.016
nitrogen compound transportGO:0071705490.015
gtp catabolic processGO:0006184460.015
oxoacid metabolic processGO:0043436470.015
purine nucleotide metabolic processGO:0006163950.015
tube formationGO:003514820.015
regulation of sequence specific dna binding transcription factor activityGO:005109030.015
positive regulation of neurogenesisGO:005076940.015
regulation of cell proliferationGO:00421271050.015
Mouse
carbohydrate derivative catabolic processGO:1901136820.015
defense response to other organismGO:00985421000.015
neuromuscular junction developmentGO:000752820.015
mitochondrion organizationGO:0007005200.015
neuron recognitionGO:0008038830.015
Worm
regulation of purine nucleotide catabolic processGO:0033121350.015
bmp signaling pathwayGO:003050930.014
cellular protein localizationGO:0034613750.014
positive regulation of cellular catabolic processGO:0031331350.014
cellular nitrogen compound catabolic processGO:00442701190.014
negative regulation of signal transductionGO:0009968600.014
regulation of stem cell differentiationGO:200073610.014
epithelial cell proliferationGO:005067310.014
ribonucleoside catabolic processGO:0042454770.014
negative regulation of neurogenesisGO:005076840.014
single organism intracellular transportGO:1902582700.014
ribonucleoside metabolic processGO:0009119980.014
glycosyl compound metabolic processGO:19016571000.014
regulation of transcription from rna polymerase ii promoterGO:00063571450.014
Mouse Worm Fly
nucleotide catabolic processGO:0009166770.014
adult behaviorGO:003053430.014
ribonucleoside triphosphate catabolic processGO:0009203720.014
cellular amine metabolic processGO:0044106150.014
chemosensory behaviorGO:0007635330.013
negative regulation of programmed cell deathGO:0043069190.013
nucleoside phosphate catabolic processGO:1901292770.013
defense response to gram negative bacteriumGO:0050829640.013
positive regulation of molecular functionGO:0044093610.013
oocyte differentiationGO:0009994450.013
cellular protein modification processGO:00064642070.013
establishment of organelle localizationGO:00516561230.013
regulation of nucleotide metabolic processGO:0006140370.013
positive regulation of transportGO:0051050320.013
negative regulation of nematode larval developmentGO:00610642080.013
oocyte developmentGO:0048599440.013
autophagyGO:0006914290.013
olfactory behaviorGO:0042048270.013
mesodermal cell differentiationGO:0048333150.013
Worm
establishment or maintenance of cell polarityGO:0007163630.013
nucleoside metabolic processGO:0009116990.013
lipid metabolic processGO:0006629770.013
apoptotic cell clearanceGO:00432771110.012
positive regulation of nematode larval developmentGO:0061063540.012
defense responseGO:00069522960.012
purine ribonucleoside triphosphate catabolic processGO:0009207720.012
positive regulation of cell projection organizationGO:003134640.012
regulation of protein metabolic processGO:0051246810.012
filopodium assemblyGO:004684720.012
regulation of hydrolase activityGO:0051336450.012
regulation of epithelial cell proliferationGO:005067810.012
nucleoside triphosphate catabolic processGO:0009143720.012
positive regulation of post embryonic developmentGO:0048582540.012
ribose phosphate metabolic processGO:0019693990.012
nucleoside phosphate metabolic processGO:00067531080.012
negative regulation of transcription dna templatedGO:0045892530.012
Mouse Fly
vesicle organizationGO:0016050150.012
mechanosensory behaviorGO:0007638250.012
regulation of apoptotic signaling pathwayGO:200123310.012
positive regulation of gtp catabolic processGO:0033126280.011
cell proliferationGO:00082831160.011
Zebrafish Mouse
regulation of localizationGO:00328791940.011
sensory organ morphogenesisGO:009059620.011
Zebrafish Mouse Fly
organonitrogen compound biosynthetic processGO:1901566440.011
nucleotide metabolic processGO:00091171080.011
regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139210.011
single organism catabolic processGO:00447121290.011
engulfment of apoptotic cellGO:0043652940.011
regulation of epithelial cell differentiationGO:003085640.011
Mouse
muscle fiber developmentGO:004874720.011
negative regulation of post embryonic developmentGO:00485812080.011
protein phosphorylationGO:0006468850.011
regulation of cellular ketone metabolic processGO:001056530.011
regulation of transcription from rna polymerase ii promoter in response to salt stressGO:006141610.011
positive regulation of organ growthGO:004662240.011
Mouse
single organism biosynthetic processGO:0044711910.011
regulation of synaptic plasticityGO:004816710.011
proximal distal pattern formationGO:000995460.011
ribonucleoprotein complex assemblyGO:002261840.011
positive regulation of gene expressionGO:00106281120.011
Mouse Worm
cell cycle g1 s phase transitionGO:004484320.011
positive regulation of vulval developmentGO:0040026520.011
regulation of synapse assemblyGO:005196320.011
regulation of programmed cell deathGO:0043067500.011
cellular amino acid metabolic processGO:0006520150.010
oocyte constructionGO:000730820.010
protein modification processGO:00362112070.010
cell surface receptor signaling pathwayGO:00071661490.010
purine nucleoside triphosphate metabolic processGO:0009144870.010
axonal fasciculationGO:0007413790.010
Worm
regulation of protein stabilityGO:003164730.010

tbx-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
musculoskeletal system diseaseDOID:1700.017