Caenorhabditis elegans

25 known processes

ifa-1 (CELE_F38B2.1)

Protein IFA-1

ifa-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transportGO:000681010930.691
Mouse Worm
post embryonic developmentGO:000979121520.673
cell migrationGO:00164773060.619
Mouse
establishment of localizationGO:005123411710.579
Mouse Worm Fly
endocytosisGO:00068978190.537
Worm
regulation of locomotionGO:00400121610.502
Mouse
agingGO:00075688120.472
Human Zebrafish Worm Fly
embryo developmentGO:000979030520.462
locomotionGO:004001116340.449
Mouse Worm
protein catabolic processGO:00301631620.419
Worm
nuclear pore distributionGO:003108120.396
Worm Fly
vesicle mediated transportGO:00161928520.391
Worm
single organism signalingGO:00447004010.360
Mouse Fly
single organism localizationGO:19025785180.342
Mouse Worm Fly
muscle tissue developmentGO:006053710.334
Mouse
organic substance catabolic processGO:19015752940.330
Worm
catabolic processGO:00090563180.310
Worm
localization of cellGO:00516743130.309
Mouse
cell motilityGO:00488703130.309
Mouse
embryo development ending in birth or egg hatchingGO:000979229920.268
receptor mediated endocytosisGO:00068987150.261
Worm
organelle organizationGO:00069967830.251
protein complex subunit organizationGO:00718222800.236
Worm Fly
regulation of multicellular organismal processGO:00512397260.226
Worm
cytoskeleton organizationGO:00070103390.223
Mouse Worm Fly
er nucleus signaling pathwayGO:0006984660.218
Mouse
cellular component assemblyGO:00226072930.216
Worm Fly
negative regulation of multicellular organismal processGO:00512412360.214
signalingGO:00230524010.208
Mouse Fly
cellular component movementGO:00069283880.207
Mouse
meiotic nuclear divisionGO:00071263000.203
regulation of developmental processGO:00507936840.194
Human Zebrafish Worm
macromolecule catabolic processGO:00090572020.178
Worm
developmental process involved in reproductionGO:000300611650.178
Worm Fly
regulation of cell communicationGO:00106461760.169
Mouse
response to chemicalGO:00422213560.167
Human
multicellular organismal agingGO:00102598120.166
Worm
muscle organ morphogenesisGO:004864440.159
Fly
single organism transportGO:00447654470.153
Mouse
regulation of biological qualityGO:00650087410.151
Fly
protein metabolic processGO:00195384220.150
Worm
cell projection organizationGO:00300302310.149
determination of adult lifespanGO:00083408120.145
Worm
phosphorus metabolic processGO:00067932320.145
deathGO:00162655470.144
Mouse
organic substance biosynthetic processGO:19015763230.141
Fly
macromolecule localizationGO:00330367710.139
Mouse Worm Fly
programmed cell deathGO:00125015000.134
Mouse
cell cycleGO:00070495260.132
neuron differentiationGO:00301822170.132
actomyosin structure organizationGO:00310321540.129
Worm
regulation of signalingGO:00230511720.129
Mouse
sex differentiationGO:00075489090.124
Worm Fly
reproductive structure developmentGO:00486088500.121
Worm Fly
growthGO:00400075620.118
anatomical structure homeostasisGO:0060249110.118
cellular response to chemical stimulusGO:00708871290.117
Human
purine nucleoside triphosphate catabolic processGO:0009146720.115
muscle cell developmentGO:00550011580.114
Mouse Worm
striated muscle cell developmentGO:00550021570.108
Mouse Worm
negative regulation of biological processGO:00485195670.108
Mouse Worm Fly
nucleoside catabolic processGO:0009164780.108
organ developmentGO:004851311020.106
Human Mouse Worm Fly
cell developmentGO:00484686960.106
Mouse Worm
microtubule based processGO:00070171820.104
Mouse Fly
actin cytoskeleton organizationGO:00300361840.103
Worm Fly
meiotic cell cycleGO:00513213350.101
striated muscle myosin thick filament assemblyGO:00716881380.095
Worm
regulation of cell migrationGO:0030334550.094
Mouse
response to external stimulusGO:00096052890.093
lipid localizationGO:00108765730.093
cellular component biogenesisGO:00440852970.091
Worm Fly
regulation of cell cycleGO:00517261940.091
Worm
regulation of cellular component organizationGO:00511282480.087
Mouse Fly
regulation of metabolic processGO:00192224780.085
Mouse Fly
cellular nitrogen compound catabolic processGO:00442701190.084
organelle assemblyGO:00709252140.084
Worm
maintenance of locationGO:00512355800.083
cell cycle processGO:00224024820.082
Worm Fly
muscle organ developmentGO:0007517260.082
Human Fly
regulation of response to stimulusGO:00485832430.080
Mouse
anatomical structure formation involved in morphogenesisGO:00486462500.079
Worm
nuclear pore localizationGO:005166420.079
Worm Fly
regulation of localizationGO:00328791940.075
Mouse
cellular component morphogenesisGO:00329893180.075
Worm
organelle fissionGO:00482853630.074
mitotic nuclear divisionGO:0007067890.073
Worm
multicellular organismal reproductive processGO:00486098150.073
Worm Fly
behaviorGO:00076105270.073
Worm Fly
developmental growthGO:00485894120.072
Worm
nucleus localizationGO:0051647550.071
Fly
single organism organelle organizationGO:19025895010.071
Mouse Worm Fly
single organism catabolic processGO:00447121290.071
inductive cell migrationGO:00400391450.071
regulation of signal transductionGO:00099661350.071
Mouse
development of primary sexual characteristicsGO:00451378400.070
Worm Fly
striated muscle cell differentiationGO:00511461580.070
Mouse Worm
lipid storageGO:00199155650.069
apoptotic processGO:00069154780.069
Mouse
cellular localizationGO:00516413600.068
Mouse Worm Fly
regulation of cell differentiationGO:0045595810.068
regulation of nucleobase containing compound metabolic processGO:00192192220.068
Mouse Fly
negative regulation of developmental processGO:00510932270.067
gamete generationGO:00072764610.066
Worm Fly
regulation of system processGO:0044057270.066
positive regulation of developmental processGO:00510944080.065
Human Worm
biosynthetic processGO:00090583230.065
Fly
localization within membraneGO:005166820.064
Worm Fly
negative regulation of cellular component organizationGO:0051129330.064
Mouse
gonad developmentGO:00084068400.064
Worm Fly
molting cycle collagen and cuticulin based cuticleGO:00189962810.064
Worm
regulation of growthGO:00400084090.061
Worm
regulation of cytoskeleton organizationGO:0051493410.061
Fly
cellular response to stressGO:00335541620.059
Human Mouse
macromolecular complex assemblyGO:00650031930.059
Worm Fly
positive regulation of developmental growthGO:00486393540.059
Worm
positive regulation of growthGO:00459273690.059
Worm
actin filament based processGO:00300291910.058
Worm Fly
cellular macromolecule biosynthetic processGO:00346452470.058
Fly
phagocytosisGO:00069091150.057
protein complex assemblyGO:00064611860.057
Worm Fly
cellular component assembly involved in morphogenesisGO:00109271830.057
Worm
ion transportGO:00068111130.057
multi organism reproductive processGO:00447038670.056
Worm Fly
single organism reproductive processGO:004470211960.056
Worm Fly
cell deathGO:00082195470.056
Mouse
cell fate commitmentGO:00451651390.055
Fly
mitotic cell cycle processGO:19030471940.054
Worm Fly
establishment of organelle localizationGO:00516561230.053
Fly
negative regulation of response to stimulusGO:0048585730.053
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001121880.052
Mouse Fly
protein modification processGO:00362112070.052
muscle cell differentiationGO:00426921710.051
Mouse Worm
purine ribonucleoside catabolic processGO:0046130750.050
positive regulation of biosynthetic processGO:00098911090.050
Mouse
regulation of multicellular organism growthGO:00400143730.050
Worm
mitochondrion organizationGO:0007005200.050
Mouse
protein complex biogenesisGO:00702711860.050
Worm Fly
body morphogenesisGO:00101716200.049
Worm
regulation of macromolecule biosynthetic processGO:00105561890.049
Mouse Fly
establishment of localization in cellGO:00516493180.049
Mouse Fly
negative regulation of signal transductionGO:0009968600.048
Mouse
ovipositionGO:00189913640.047
Worm
myosin filament assemblyGO:00310341380.047
Worm
organophosphate catabolic processGO:0046434810.046
regulation of cellular metabolic processGO:00313233050.046
Mouse Fly
defense response to bacteriumGO:0042742860.046
neuron projection developmentGO:00311751870.046
multicellular organism reproductionGO:00325048190.045
Worm Fly
cell surface receptor signaling pathwayGO:00071661490.045
Mouse
myofibril assemblyGO:00302391540.045
Worm
secretionGO:00469031470.045
cell recognitionGO:0008037850.045
organic cyclic compound catabolic processGO:19013611190.045
macromolecule biosynthetic processGO:00090592500.044
Fly
negative regulation of cellular processGO:00485232390.043
Mouse Worm Fly
purine ribonucleoside triphosphate catabolic processGO:0009207720.043
reproductive system developmentGO:00614588500.043
Worm Fly
small molecule metabolic processGO:00442811860.042
endoplasmic reticulum unfolded protein responseGO:0030968660.042
nucleotide catabolic processGO:0009166770.042
positive regulation of multicellular organism growthGO:00400183520.041
Worm
negative regulation of metabolic processGO:00098922400.041
Fly
regulation of developmental growthGO:00486383890.041
Worm
cuticle developmentGO:00423351000.039
Worm Fly
regulation of cellular component movementGO:0051270620.039
Mouse
sexual reproductionGO:00199535460.039
Worm Fly
positive regulation of cellular metabolic processGO:00313251780.039
Mouse
phosphate containing compound metabolic processGO:00067962320.038
macromolecular complex subunit organizationGO:00439333200.038
Worm Fly
nucleoside metabolic processGO:0009116990.037
response to woundingGO:000961140.037
immune responseGO:00069551920.037
multi multicellular organism processGO:00447063900.036
Worm
tube developmentGO:00352951260.036
Fly
negative regulation of cell cycleGO:0045786530.036
Worm
cellular macromolecular complex assemblyGO:00346221840.036
Worm Fly
regulation of rna metabolic processGO:00512521730.036
Mouse Fly
cellular protein localizationGO:0034613750.035
Mouse Worm Fly
signal transductionGO:00071653170.035
Mouse
regulation of cellular biosynthetic processGO:00313261890.035
Mouse Fly
cellular catabolic processGO:00442481990.035
glycosyl compound metabolic processGO:19016571000.035
purine ribonucleotide catabolic processGO:0009154750.034
response to endoplasmic reticulum stressGO:0034976710.034
organonitrogen compound catabolic processGO:1901565900.034
regulation of muscle system processGO:0090257200.033
cellular protein modification processGO:00064642070.033
positive regulation of macromolecule biosynthetic processGO:00105571090.033
Mouse
regulation of gene expressionGO:00104683660.033
Mouse Fly
nucleoside phosphate catabolic processGO:1901292770.033
myosin filament organizationGO:00310331380.032
Worm
neuron developmentGO:00486661990.032
chromosome segregationGO:00070591800.032
Worm
positive regulation of multicellular organismal processGO:00512404170.032
Worm
negative regulation of cell communicationGO:0010648610.032
Mouse
nucleobase containing compound catabolic processGO:00346551140.032
cellular nitrogen compound biosynthetic processGO:00442711920.032
Fly
carbohydrate derivative catabolic processGO:1901136820.032
eating behaviorGO:0042755590.032
defense response to other organismGO:00985421000.032
digestive tract developmentGO:00485651220.032
Fly
protein localizationGO:00081042050.031
Mouse Worm Fly
regulation of cellular localizationGO:0060341420.031
Mouse
negative regulation of cellular metabolic processGO:0031324950.030
Fly
response to organic substanceGO:00100331310.030
molting cycleGO:00423032810.030
Worm
post embryonic organ developmentGO:00485693360.030
negative regulation of signalingGO:0023057610.030
Mouse
collagen and cuticulin based cuticle developmentGO:0040002990.029
Worm
regulation of primary metabolic processGO:00800902920.029
Mouse Fly
head developmentGO:006032210.029
nervous system developmentGO:00073992530.029
Fly
regulation of multicellular organismal developmentGO:20000263170.029
cellular protein complex assemblyGO:00436231780.029
Worm Fly
neuron recognitionGO:0008038830.029
positive regulation of gene expressionGO:00106281120.028
Mouse
axon developmentGO:00615641630.028
genitalia developmentGO:00488067410.028
Worm
regulation of apoptotic signaling pathwayGO:200123310.028
Mouse
system processGO:00030081360.028
Zebrafish
mitotic nuclear envelope reassemblyGO:000708430.027
Fly
intracellular signal transductionGO:0035556960.027
heterocycle catabolic processGO:00467001190.027
regulation of nitrogen compound metabolic processGO:00511712220.027
Mouse Fly
regulation of catalytic activityGO:0050790780.027
regulation of organelle organizationGO:00330431640.027
Mouse Fly
ribonucleoside catabolic processGO:0042454770.026
gene expressionGO:00104674120.026
Fly
ribonucleoside triphosphate catabolic processGO:0009203720.026
establishment of spindle localizationGO:0051293510.026
negative regulation of macromolecule metabolic processGO:00106052290.026
Fly
glycosyl compound catabolic processGO:1901658790.026
homeostatic processGO:0042592510.025
digestive system developmentGO:00551231220.025
Fly
reproductive behaviorGO:00190983870.025
Worm
regulation of cell motilityGO:2000145570.025
Mouse
feeding behaviorGO:0007631700.025
regulation of molecular functionGO:0065009890.024
cell proliferationGO:00082831160.024
Worm
nucleus organizationGO:0006997380.024
Mouse Worm Fly
cellular response to organic substanceGO:00713101190.024
multicellular organismal reproductive behaviorGO:00330573840.024
Worm
positive regulation of macromolecule metabolic processGO:00106041490.024
Mouse
ras protein signal transductionGO:0007265310.024
nucleoside triphosphate catabolic processGO:0009143720.024
cellular response to unfolded proteinGO:0034620710.024
response to oxygen containing compoundGO:1901700440.023
cellular biosynthetic processGO:00442493150.023
Fly
nucleobase containing compound metabolic processGO:00061394060.023
Fly
organic anion transportGO:0015711200.023
positive regulation of metabolic processGO:00098931870.022
Mouse
response to acid chemicalGO:000110140.022
carbohydrate derivative metabolic processGO:19011351410.022
ribonucleotide catabolic processGO:0009261750.022
regulation of biosynthetic processGO:00098891890.021
Mouse Fly
response to abiotic stimulusGO:00096281520.021
Human
regulation of mitotic cell cycleGO:0007346760.021
Worm
tissue developmentGO:00098881120.021
Mouse Fly
regulation of transportGO:0051049910.021
ion homeostasisGO:0050801210.021
ribonucleoside metabolic processGO:0009119980.021
cellular protein metabolic processGO:00442672790.021
positive regulation of transportGO:0051050320.021
meiotic cell cycle processGO:19030461700.021
single organism cellular localizationGO:1902580720.020
Mouse Worm Fly
macromolecule modificationGO:00434122180.020
regulation of protein metabolic processGO:0051246810.020
protein phosphorylationGO:0006468850.020
regulation of transferase activityGO:0051338310.020
positive regulation of cellular processGO:00485223320.020
Human Mouse Worm
regulation of actin filament based processGO:0032970220.020
Fly
response to external biotic stimulusGO:00432071010.019
single organism intracellular transportGO:1902582700.019
Mouse
cellular macromolecule localizationGO:0070727750.019
Mouse Worm Fly
cation homeostasisGO:0055080200.019
taxisGO:00423301280.019
negative regulation of gene expression epigeneticGO:004581420.019
Fly
cation transportGO:0006812780.019
spindle organizationGO:0007051920.019
regulation of cell cycle processGO:00105641450.019
purine containing compound metabolic processGO:0072521950.019
ribonucleotide metabolic processGO:0009259990.018
protein transportGO:0015031450.018
Mouse
organic substance transportGO:00717021130.018
Mouse
male anatomical structure morphogenesisGO:0090598780.018
rna metabolic processGO:00160702280.018
Fly
positive regulation of phosphorus metabolic processGO:0010562560.018
female gamete generationGO:00072922540.018
nucleoside triphosphate metabolic processGO:0009141870.018
purine ribonucleoside metabolic processGO:0046128920.018
purine nucleotide catabolic processGO:0006195750.018
regulation of intracellular signal transductionGO:1902531770.018
chemotaxisGO:00069351200.017
neurogenesisGO:00220082360.017
posttranscriptional regulation of gene expressionGO:00106081660.017
hermaphrodite genitalia developmentGO:00400357340.017
Worm
apoptotic mitochondrial changesGO:000863720.017
Mouse
regulation of apoptotic processGO:0042981360.017
Mouse
aromatic compound catabolic processGO:00194391160.017
multicellular organism growthGO:00352643850.017
Worm
purine nucleoside catabolic processGO:0006152750.016
anion transportGO:0006820300.016
actin filament bundle assemblyGO:005101730.016
cell divisionGO:00513012620.016
axonal fasciculationGO:0007413790.016
skeletal muscle organ developmentGO:006053830.016
adult behaviorGO:003053430.016
Fly
cytokinesisGO:0000910800.016
cellular protein complex localizationGO:003462930.016
Worm Fly
organophosphate metabolic processGO:00196371250.016
protein complex localizationGO:003150330.016
Worm Fly
actin filament organizationGO:0007015210.016
Fly
excretionGO:0007588490.016
membrane invaginationGO:0010324980.015
engulfment of apoptotic cellGO:0043652940.015
regulation of cellular protein metabolic processGO:0032268750.015
muscle contractionGO:0006936430.015
regulation of cellular amino acid metabolic processGO:000652100.015
regulation of cell deathGO:0010941650.015
Mouse
response to topologically incorrect proteinGO:0035966820.015
transcription from rna polymerase ii promoterGO:00063661490.015
cellular response to topologically incorrect proteinGO:0035967760.015
cell cell signalingGO:00072671180.015
Fly
negative regulation of biosynthetic processGO:0009890650.015
Fly
generation of neuronsGO:00486992350.014
purine ribonucleoside triphosphate metabolic processGO:0009205870.014
pharyngeal pumpingGO:0043050580.014
nucleobase containing compound biosynthetic processGO:00346541840.014
Fly
single organism membrane organizationGO:0044802350.014
Mouse Fly
response to bacteriumGO:0009617860.014
aromatic compound biosynthetic processGO:00194381920.014
Fly
chromosome organizationGO:00512761040.014
Fly
single organism behaviorGO:0044708830.014
Fly
adult locomotory behaviorGO:000834410.014
Fly
response to biotic stimulusGO:00096071010.014
defense responseGO:00069522960.013
rna biosynthetic processGO:00327741690.013
Fly
oxoacid metabolic processGO:0043436470.013
positive regulation of locomotionGO:0040017420.013
membrane organizationGO:00610241350.013
Mouse Fly
response to other organismGO:00517071010.013
multi organism reproductive behaviorGO:00447053870.013
Worm
negative regulation of apoptotic processGO:0043066170.013
Mouse
regulation of protein serine threonine kinase activityGO:0071900180.013
multi organism behaviorGO:00517053890.013
Worm
atp catabolic processGO:0006200270.013
muscle system processGO:0003012430.013
nucleobase containing small molecule metabolic processGO:00550861150.013
regulation of muscle contractionGO:0006937200.013
regulation of mitochondrion organizationGO:001082110.013
Mouse
muscle cell cellular homeostasisGO:004671650.013
carboxylic acid metabolic processGO:0019752340.013
regulation of behaviorGO:0050795970.013
regulation of macromolecule metabolic processGO:00602554210.013
Mouse Fly
cell part morphogenesisGO:00329901520.013
positive regulation of nitrogen compound metabolic processGO:00511731340.012
Mouse
organonitrogen compound metabolic processGO:19015641510.012
apoptotic cell clearanceGO:00432771110.012
vulval developmentGO:00400253330.012
nucleotide metabolic processGO:00091171080.012
organic cyclic compound biosynthetic processGO:19013621950.012
Fly
chemical homeostasisGO:0048878290.012
purine ribonucleoside monophosphate metabolic processGO:0009167430.012
ribonucleoside triphosphate metabolic processGO:0009199870.012
positive regulation of molecular functionGO:0044093610.012
lateral inhibitionGO:004633130.012
Fly
nitrogen compound transportGO:0071705490.012
positive regulation of rna metabolic processGO:00512541030.012
Mouse
regulation of nucleic acid templated transcriptionGO:19035061650.012
Mouse Fly
protein importGO:001703890.012
Mouse
negative regulation of macromolecule biosynthetic processGO:0010558650.012
Fly
regulation of protein kinase activityGO:0045859280.012
regulation of transcription dna templatedGO:00063551640.011
Mouse Fly
regulation of phosphorylationGO:0042325450.011
regulation of nematode larval developmentGO:00610622600.011
germ cell developmentGO:00072813510.011
Worm
negative regulation of nematode larval developmentGO:00610642080.011
somatic muscle developmentGO:000752510.011
phagocytosis engulfmentGO:0006911980.011
regulation of programmed cell deathGO:0043067500.011
Mouse
negative regulation of gene expressionGO:00106292170.011
Fly
purine ribonucleotide metabolic processGO:0009150950.011
purine nucleotide metabolic processGO:0006163950.011
regulation of cell proliferationGO:00421271050.011
Worm
positive regulation of cysteine type endopeptidase activityGO:200105630.011
negative regulation of nucleobase containing compound metabolic processGO:0045934630.011
Fly
establishment of protein localizationGO:0045184500.011
Mouse
ovulationGO:0030728330.011
positive regulation of protein transportGO:005122240.010
muscle fiber developmentGO:004874720.010
positive regulation of rna biosynthetic processGO:19026801020.010
Mouse
epithelial tube morphogenesisGO:006056210.010
Fly
ribonucleoside monophosphate metabolic processGO:0009161450.010
regulation of chromosome segregationGO:0051983200.010
Worm
cell morphogenesisGO:00009021630.010

ifa-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
progeriaDOID:391100.701
Human
muscle tissue diseaseDOID:6600.378
Human
disease of anatomical entityDOID:700.378
Human
congenital muscular dystrophyDOID:005055700.378
Human
muscular dystrophyDOID:988400.378
Human
musculoskeletal system diseaseDOID:1700.378
Human
myopathyDOID:42300.378
Human
muscular diseaseDOID:008000000.378
Human
lipodystrophyDOID:81100.376
Human
integumentary system diseaseDOID:1600.376
Human
skin diseaseDOID:3700.376
Human
familial partial lipodystrophyDOID:005044000.376
Human
heart diseaseDOID:11400.324
Human
cardiovascular system diseaseDOID:128700.324
Human
cardiomyopathyDOID:005070000.324
Human
dilated cardiomyopathyDOID:1293000.094
Human
intrinsic cardiomyopathyDOID:006003600.094
Human
emery dreifuss muscular dystrophyDOID:1172600.072
Human
nervous system diseaseDOID:86300.043
Human
neuropathyDOID:87000.043
Human
neuromuscular diseaseDOID:44000.043
Human
charcot marie tooth diseaseDOID:1059500.043
Human
charcot marie tooth disease type 2DOID:005053900.043
Human
limb girdle muscular dystrophyDOID:1172400.027
Human
hypertrophic cardiomyopathyDOID:1198400.012