Caenorhabditis elegans

59 known processes

pmk-2 (CELE_F42G8.3)

Protein PMK-2

pmk-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979121520.273
embryo development ending in birth or egg hatchingGO:000979229920.240
embryo developmentGO:000979030520.215
organ developmentGO:004851311020.211
establishment of localizationGO:005123411710.174
Mouse Worm
genitalia developmentGO:00488067410.153
locomotionGO:004001116340.132
multicellular organismal agingGO:00102598120.128
Worm Fly
single organism organelle organizationGO:19025895010.118
Worm
single organism signalingGO:00447004010.114
transportGO:000681010930.102
Mouse Worm
hermaphrodite genitalia developmentGO:00400357340.099
regulation of multicellular organismal processGO:00512397260.097
Human Mouse Fly
regulation of biological qualityGO:00650087410.093
Mouse Worm Fly
positive regulation of developmental growthGO:00486393540.089
Fly
nucleobase containing compound metabolic processGO:00061394060.087
Mouse Worm
regulation of rna metabolic processGO:00512521730.086
Mouse Worm Fly
regulation of macromolecule metabolic processGO:00602554210.085
Mouse Worm Fly
positive regulation of metabolic processGO:00098931870.081
Human Mouse Worm Fly
organelle organizationGO:00069967830.081
Worm
behaviorGO:00076105270.079
determination of adult lifespanGO:00083408120.077
Worm Fly
p38mapk cascadeGO:003806620.075
Mouse Worm
vesicle mediated transportGO:00161928520.073
regulation of metabolic processGO:00192224780.067
Human Mouse Worm Fly
gene expressionGO:00104674120.067
Mouse Worm
gonad developmentGO:00084068400.064
vulval developmentGO:00400253330.064
positive regulation of jnk cascadeGO:004633030.064
regulation of primary metabolic processGO:00800902920.063
Mouse Worm Fly
macromolecule localizationGO:00330367710.062
Mouse Worm
sex differentiationGO:00075489090.062
regulation of growthGO:00400084090.062
Fly
maintenance of locationGO:00512355800.061
regulation of nucleobase containing compound metabolic processGO:00192192220.060
Mouse Worm Fly
lipid storageGO:00199155650.060
developmental growthGO:00485894120.059
Mouse Fly
regulation of gene expressionGO:00104683660.058
Mouse Worm Fly
programmed cell deathGO:00125015000.058
Worm
rna metabolic processGO:00160702280.058
Mouse Worm
positive regulation of multicellular organismal processGO:00512404170.058
Human Mouse Fly
cell cycle processGO:00224024820.057
Mouse
cell deathGO:00082195470.056
Worm
cell developmentGO:00484686960.056
Mouse Worm
lipid localizationGO:00108765730.055
nucleic acid metabolic processGO:00903042990.055
Mouse Worm
regulation of developmental growthGO:00486383890.054
Fly
regulation of cellular metabolic processGO:00313233050.053
Human Mouse Worm Fly
regulation of vulval developmentGO:00400282480.052
multicellular organism reproductionGO:00325048190.052
Worm
germ cell developmentGO:00072813510.051
Worm
macromolecule biosynthetic processGO:00090592500.050
Mouse Worm
regulation of developmental processGO:00507936840.050
Mouse Fly
positive regulation of developmental processGO:00510944080.049
Mouse Fly
signalingGO:00230524010.049
heterocycle biosynthetic processGO:00181301870.048
Mouse Worm
single organism localizationGO:19025785180.048
Mouse Worm
deathGO:00162655470.047
Worm
positive regulation of multicellular organism growthGO:00400183520.047
Fly
negative regulation of developmental processGO:00510932270.046
protein modification processGO:00362112070.046
endocytosisGO:00068978190.046
gamete generationGO:00072764610.046
Worm
response to external stimulusGO:00096052890.045
Human Mouse Worm Fly
regulation of post embryonic developmentGO:00485802600.045
multi organism reproductive processGO:00447038670.045
Worm
organic substance biosynthetic processGO:19015763230.045
Mouse Worm
positive regulation of stress activated mapk cascadeGO:003287430.045
organelle localizationGO:00516401270.044
Worm
agingGO:00075688120.044
Human Worm Fly
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.043
post embryonic organ developmentGO:00485693360.042
Fly
stress activated protein kinase signaling cascadeGO:0031098100.042
Mouse Rat Worm
sensory organ morphogenesisGO:009059620.041
stress activated mapk cascadeGO:0051403100.041
Mouse Rat Worm
cellular process involved in reproduction in multicellular organismGO:00224123510.041
Worm
meiotic nuclear divisionGO:00071263000.041
Worm
small molecule metabolic processGO:00442811860.041
Mouse
regulation of biosynthetic processGO:00098891890.040
Mouse Worm Fly
establishment of localization in cellGO:00516493180.040
Mouse Worm
apoptotic processGO:00069154780.040
Worm
regulation of nitrogen compound metabolic processGO:00511712220.040
Mouse Worm Fly
developmental process involved in reproductionGO:000300611650.040
growthGO:00400075620.040
Mouse Fly
phosphorus metabolic processGO:00067932320.039
regulation of multicellular organism growthGO:00400143730.039
Fly
reproductive behaviorGO:00190983870.039
macromolecular complex subunit organizationGO:00439333200.039
Worm
muscle organ morphogenesisGO:004864440.038
negative regulation of macromolecule metabolic processGO:00106052290.038
reproductive system developmentGO:00614588500.038
cellular protein complex assemblyGO:00436231780.037
Worm
development of primary sexual characteristicsGO:00451378400.037
organic cyclic compound biosynthetic processGO:19013621950.037
Mouse Worm
nucleobase containing compound biosynthetic processGO:00346541840.037
Mouse Worm
cellular nitrogen compound biosynthetic processGO:00442711920.037
Mouse Worm
generation of neuronsGO:00486992350.037
response to endoplasmic reticulum stressGO:0034976710.035
Worm
establishment of vesicle localizationGO:0051650230.035
Worm
aromatic compound biosynthetic processGO:00194381920.034
Mouse Worm
cell divisionGO:00513012620.034
regulation of nematode larval developmentGO:00610622600.034
establishment of organelle localizationGO:00516561230.034
Worm
innate immune responseGO:00450871900.034
Worm Fly
organonitrogen compound metabolic processGO:19015641510.033
receptor mediated endocytosisGO:00068987150.033
reproductive structure developmentGO:00486088500.032
anatomical structure formation involved in morphogenesisGO:00486462500.032
Mouse Worm
jnk cascadeGO:000725480.032
Worm
regulation of nucleic acid templated transcriptionGO:19035061650.031
Mouse Worm Fly
single organism transportGO:00447654470.031
Mouse Worm
protein metabolic processGO:00195384220.031
oogenesisGO:00484772290.031
Worm
protein complex subunit organizationGO:00718222800.029
Worm
biosynthetic processGO:00090583230.029
Mouse Worm
female gamete generationGO:00072922540.029
Worm
response to heatGO:0009408500.028
Worm Fly
skeletal muscle organ developmentGO:006053830.028
Mouse
response to woundingGO:000961140.028
Mouse
muscle structure developmentGO:00610611910.027
Human Mouse Worm
cellular component morphogenesisGO:00329893180.027
Mouse Worm
multicellular organismal reproductive processGO:00486098150.027
Worm
single organism reproductive processGO:004470211960.027
ribose phosphate metabolic processGO:0019693990.027
negative regulation of post embryonic developmentGO:00485812080.027
cellular response to inorganic substanceGO:007124130.026
Fly
positive regulation of cellular metabolic processGO:00313251780.026
Human Mouse Worm Fly
positive regulation of cellular processGO:00485223320.026
Human Mouse Worm Fly
regulation of cellular macromolecule biosynthetic processGO:20001121880.026
Mouse Worm Fly
sexual reproductionGO:00199535460.026
Worm
actin filament based processGO:00300291910.025
Worm
defense response to gram positive bacteriumGO:0050830310.025
Worm
multi multicellular organism processGO:00447063900.025
catabolic processGO:00090563180.025
immune responseGO:00069551920.025
Worm Fly
cell part morphogenesisGO:00329901520.025
negative regulation of multicellular organismal processGO:00512412360.025
protein complex biogenesisGO:00702711860.025
Worm
regulation of cell cycle processGO:00105641450.025
multicellular organism growthGO:00352643850.025
Fly
positive regulation of rna metabolic processGO:00512541030.025
Mouse Worm
organelle fissionGO:00482853630.024
Worm
nucleic acid templated transcriptionGO:00976591690.024
Mouse Worm
carbohydrate derivative metabolic processGO:19011351410.024
neuron projection developmentGO:00311751870.024
nucleotide metabolic processGO:00091171080.024
negative regulation of vulval developmentGO:00400272060.024
regulation of multicellular organismal developmentGO:20000263170.024
Mouse Fly
phosphate containing compound metabolic processGO:00067962320.023
body morphogenesisGO:00101716200.023
negative regulation of gene expressionGO:00106292170.023
cytoskeleton organizationGO:00070103390.022
Worm
response to temperature stimulusGO:0009266660.022
Worm Fly
striated muscle cell differentiationGO:00511461580.022
Mouse Worm
cellular localizationGO:00516413600.022
Mouse Worm
peptidyl amino acid modificationGO:0018193580.022
Human Mouse Worm
dna metabolic processGO:0006259740.022
regulation of gene expression epigeneticGO:00400291630.021
neuromuscular junction developmentGO:000752820.021
actin cytoskeleton organizationGO:00300361840.021
Worm
nervous system developmentGO:00073992530.021
cell morphogenesisGO:00009021630.021
Mouse
positive regulation of biosynthetic processGO:00098911090.021
Mouse Worm
cell morphogenesis involved in neuron differentiationGO:00486671110.021
signal transductionGO:00071653170.020
synaptic vesicle transportGO:0048489210.020
negative regulation of biological processGO:00485195670.020
Mouse Rat Fly
negative regulation of nematode larval developmentGO:00610642080.020
neuron projection morphogenesisGO:00488121140.020
regulation of bmp signaling pathwayGO:003051030.020
Fly
muscle cell developmentGO:00550011580.020
Mouse Worm
posttranscriptional regulation of gene expressionGO:00106081660.019
response to chemicalGO:00422213560.019
Human Mouse Rat Worm Fly
defense response to other organismGO:00985421000.019
Worm Fly
macromolecule catabolic processGO:00090572020.019
ovipositionGO:00189913640.019
defense response to gram negative bacteriumGO:0050829640.019
Worm
regulation of macromolecule biosynthetic processGO:00105561890.019
Mouse Worm Fly
regulation of transcription dna templatedGO:00063551640.019
Mouse Worm Fly
positive regulation of rna biosynthetic processGO:19026801020.019
Mouse Worm
nucleobase containing compound catabolic processGO:00346551140.019
defense responseGO:00069522960.019
Worm Fly
cell type specific apoptotic processGO:009728540.019
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361820.019
nucleobase containing small molecule metabolic processGO:00550861150.019
nucleoside phosphate metabolic processGO:00067531080.019
positive regulation of growthGO:00459273690.019
Fly
cellular biosynthetic processGO:00442493150.019
Mouse Worm
regulation of phosphorus metabolic processGO:0051174810.019
Fly
microtubule based processGO:00070171820.019
cell morphogenesis involved in differentiationGO:00009041120.018
positive regulation of macromolecule biosynthetic processGO:00105571090.018
Mouse Worm
peptidyl serine modificationGO:0018209200.018
Human Mouse Worm
regulation of cell differentiationGO:0045595810.018
Mouse
cellular component movementGO:00069283880.018
Worm
cellular component assemblyGO:00226072930.018
Worm
posttranscriptional gene silencingGO:00164411430.018
head developmentGO:006032210.018
gene silencing by rnaGO:00310471430.018
cellular component biogenesisGO:00440852970.018
Worm
regulation of cellular amine metabolic processGO:003323800.017
chemotaxisGO:00069351200.017
single organism behaviorGO:0044708830.017
negative regulation of metabolic processGO:00098922400.017
regulation of organelle organizationGO:00330431640.017
actomyosin structure organizationGO:00310321540.017
Worm
positive regulation of epithelial cell proliferationGO:005067910.017
cell fate commitmentGO:00451651390.017
cellular macromolecule biosynthetic processGO:00346452470.017
Mouse Worm
striated muscle cell developmentGO:00550021570.017
Mouse Worm
posttranscriptional gene silencing by rnaGO:00351941430.017
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139310.017
muscle cell differentiationGO:00426921710.017
Human Mouse Worm
striated muscle myosin thick filament assemblyGO:00716881380.017
Worm
cellular protein metabolic processGO:00442672790.017
ribonucleotide metabolic processGO:0009259990.017
regulation of molecular functionGO:0065009890.016
protein catabolic processGO:00301631620.016
epithelial tube morphogenesisGO:006056210.016
purine ribonucleotide metabolic processGO:0009150950.016
positive regulation of cellular biosynthetic processGO:00313281090.016
Mouse Worm
protein complex assemblyGO:00064611860.016
Worm
regulation of cell communicationGO:00106461760.016
Mouse Fly
regulation of response to stimulusGO:00485832430.016
Mouse Fly
multicellular organismal reproductive behaviorGO:00330573840.016
neuron differentiationGO:00301822170.016
intracellular transportGO:0046907770.016
Mouse
cell cycleGO:00070495260.016
Mouse Rat Worm
myosin filament organizationGO:00310331380.016
Worm
cellular protein modification processGO:00064642070.016
regulation of purine nucleotide metabolic processGO:1900542370.016
macromolecular complex assemblyGO:00650031930.015
Worm
protein phosphorylationGO:0006468850.015
regulation of sequence specific dna binding transcription factor activityGO:005109030.015
bmp signaling pathwayGO:003050930.015
Fly
apoptotic cell clearanceGO:00432771110.015
organophosphate metabolic processGO:00196371250.015
positive regulation of neuron projection developmentGO:001097640.015
purine nucleotide metabolic processGO:0006163950.015
macromolecule modificationGO:00434122180.015
cellular response to chemical stimulusGO:00708871290.015
Human Mouse Fly
response to organic substanceGO:00100331310.015
Human Mouse Rat Fly
vesicle localizationGO:0051648240.015
Worm
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacteriumGO:190209740.015
Worm
regulation of signalingGO:00230511720.014
Mouse Fly
neurogenesisGO:00220082360.014
multi organism behaviorGO:00517053890.014
cell projection morphogenesisGO:00488581480.014
multi organism reproductive behaviorGO:00447053870.014
response to mechanical stimulusGO:0009612280.014
phagocytosisGO:00069091150.014
positive regulation of molecular functionGO:0044093610.014
regulation of rna biosynthetic processGO:20011411650.014
Mouse Worm Fly
axon developmentGO:00615641630.014
regulation of signal transductionGO:00099661350.014
Mouse Fly
axonogenesisGO:00074091020.014
negative regulation of response to stimulusGO:0048585730.014
Mouse Fly
single organism intracellular transportGO:1902582700.014
Mouse
establishment of mitotic spindle orientationGO:0000132280.014
cellular response to metal ionGO:007124830.013
Fly
regulation of cellular ketone metabolic processGO:001056530.013
establishment of spindle orientationGO:0051294340.013
regulation of localizationGO:00328791940.013
Mouse Worm
cellular response to stressGO:00335541620.013
Human Mouse Rat Worm Fly
positive regulation of nucleobase containing compound metabolic processGO:00459351340.013
Mouse Worm
secretion by cellGO:00329401380.013
response to external biotic stimulusGO:00432071010.013
Human Mouse Worm Fly
myosin filament assemblyGO:00310341380.013
Worm
cell cell signalingGO:00072671180.013
Worm Fly
purine containing compound metabolic processGO:0072521950.013
synaptic transmissionGO:00072681060.013
Worm Fly
cellular response to abiotic stimulusGO:007121440.013
Human
response to biotic stimulusGO:00096071010.013
Human Mouse Worm Fly
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.013
Mouse Worm
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.013
regulation of canonical wnt signaling pathwayGO:006082810.013
Mouse
purine nucleoside triphosphate metabolic processGO:0009144870.013
molting cycle collagen and cuticulin based cuticleGO:00189962810.013
cell substrate adhesionGO:003158910.013
rna interferenceGO:00162461370.012
mapk cascadeGO:0000165310.012
organic substance catabolic processGO:19015752940.012
oxoacid metabolic processGO:0043436470.012
Mouse
localization of cellGO:00516743130.012
cell surface receptor signaling pathwayGO:00071661490.012
Human Mouse Fly
molting cycleGO:00423032810.012
Fly
negative regulation of neuron differentiationGO:004566540.012
cell proliferationGO:00082831160.012
tube developmentGO:00352951260.012
phagocytosis engulfmentGO:0006911980.012
regulation of neurogenesisGO:0050767400.012
transcription from rna polymerase ii promoterGO:00063661490.012
Mouse Worm
regulation of dna replicationGO:000627550.012
carboxylic acid metabolic processGO:0019752340.011
Mouse
neuron developmentGO:00486661990.011
signal transduction by phosphorylationGO:0023014310.011
regulation of ras protein signal transductionGO:0046578410.011
positive regulation of organ growthGO:004662240.011
negative regulation of cellular processGO:00485232390.011
Mouse Rat
canonical wnt signaling pathwayGO:006007030.011
Mouse
negative regulation of neurogenesisGO:005076840.011
gene silencingGO:00164581430.011
amine metabolic processGO:0009308150.011
membrane invaginationGO:0010324980.011
positive regulation of neurogenesisGO:005076940.011
rna localizationGO:000640330.011
regulation of epithelial cell proliferationGO:005067810.011
cell migrationGO:00164773060.011
regulation of apoptotic signaling pathwayGO:200123310.011
muscle tissue developmentGO:006053710.011
Mouse
negative regulation of organ growthGO:004662110.011
glycosyl compound catabolic processGO:1901658790.011
heterocycle catabolic processGO:00467001190.011
regulation of protein stabilityGO:003164730.011
transcription dna templatedGO:00063511680.011
Mouse Worm
engulfment of apoptotic cellGO:0043652940.010
positive regulation of intracellular transportGO:003238820.010
Mouse
regulation of organ morphogenesisGO:200002740.010
establishment of synaptic vesicle localizationGO:0097480210.010
positive regulation of neuron differentiationGO:004566640.010
regulation of cellular component organizationGO:00511282480.010
Mouse Worm Fly
g1 s transition of mitotic cell cycleGO:000008220.010
neurological system processGO:0050877530.010
regulation of cellular biosynthetic processGO:00313261890.010
Mouse Worm Fly
purine nucleoside metabolic processGO:0042278920.010
ribonucleoside triphosphate catabolic processGO:0009203720.010
regulation of cytoplasmic transportGO:190364930.010
Mouse
cellular macromolecular complex assemblyGO:00346221840.010
Worm
oocyte developmentGO:0048599440.010
Worm
neuron projection guidanceGO:0097485820.010
positive regulation of macromolecule metabolic processGO:00106041490.010
Mouse Worm Fly
nucleoside triphosphate metabolic processGO:0009141870.010
positive regulation of phosphorus metabolic processGO:0010562560.010
Fly
protein localizationGO:00081042050.010
Mouse Worm
regulation of lipid metabolic processGO:001921640.010
inductive cell migrationGO:00400391450.010

pmk-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.020
organ system cancerDOID:005068600.016
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.010