Caenorhabditis elegans

58 known processes

clk-2 (CELE_C07H6.6)

Protein CLK-2

clk-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.891
cell morphogenesisGO:00009021630.585
post embryonic developmentGO:000979121520.490
regulation of metabolic processGO:00192224780.474
generation of neuronsGO:00486992350.405
transportGO:000681010930.362
neuron developmentGO:00486661990.355
organelle organizationGO:00069967830.349
regulation of cellular component organizationGO:00511282480.332
neuron projection morphogenesisGO:00488121140.298
cell projection morphogenesisGO:00488581480.277
regulation of cell proliferationGO:00421271050.246
cell part morphogenesisGO:00329901520.242
agingGO:00075688120.223
cellular biosynthetic processGO:00442493150.217
embryo developmentGO:000979030520.214
regulation of multicellular organismal processGO:00512397260.212
multicellular organism reproductionGO:00325048190.209
negative regulation of biological processGO:00485195670.200
locomotionGO:004001116340.185
gene expressionGO:00104674120.184
vesicle mediated transportGO:00161928520.184
meiotic nuclear divisionGO:00071263000.183
multi organism reproductive processGO:00447038670.180
multicellular organismal agingGO:00102598120.179
regulation of developmental processGO:00507936840.173
regulation of organelle organizationGO:00330431640.171
cell divisionGO:00513012620.168
establishment of localizationGO:005123411710.165
behaviorGO:00076105270.164
cellular component biogenesisGO:00440852970.153
anatomical structure homeostasisGO:0060249110.143
genitalia developmentGO:00488067410.141
negative regulation of cellular processGO:00485232390.140
cell morphogenesis involved in neuron differentiationGO:00486671110.135
cell type specific apoptotic processGO:009728540.134
multicellular organismal reproductive processGO:00486098150.131
cellular component morphogenesisGO:00329893180.130
regulation of macromolecule metabolic processGO:00602554210.127
organonitrogen compound metabolic processGO:19015641510.120
nucleic acid metabolic processGO:00903042990.119
cell developmentGO:00484686960.118
growthGO:00400075620.114
oocyte constructionGO:000730820.110
receptor mediated endocytosisGO:00068987150.110
cellular component assemblyGO:00226072930.109
telomere organizationGO:003220060.108
regulation of gene expressionGO:00104683660.106
purine ribonucleoside catabolic processGO:0046130750.106
regulation of cellular metabolic processGO:00313233050.105
positive regulation of multicellular organismal processGO:00512404170.102
establishment of localization in cellGO:00516493180.101
positive regulation of developmental processGO:00510944080.098
signalingGO:00230524010.097
Human
organ developmentGO:004851311020.096
neurogenesisGO:00220082360.094
multicellular organismal reproductive behaviorGO:00330573840.094
gonad developmentGO:00084068400.092
homeostatic processGO:0042592510.092
regulation of cell morphogenesisGO:0022604400.092
positive regulation of growthGO:00459273690.090
regulation of primary metabolic processGO:00800902920.088
response to chemicalGO:00422213560.087
cellular protein metabolic processGO:00442672790.087
multi multicellular organism processGO:00447063900.085
negative regulation of developmental processGO:00510932270.083
regulation of cell cycle processGO:00105641450.083
regulation of growthGO:00400084090.081
hermaphrodite genitalia developmentGO:00400357340.080
regulation of transcription from rna polymerase ii promoterGO:00063571450.079
neuromuscular junction developmentGO:000752820.079
deathGO:00162655470.078
nucleobase containing compound metabolic processGO:00061394060.077
apoptotic processGO:00069154780.077
organelle fissionGO:00482853630.077
single organism transportGO:00447654470.075
negative regulation of nucleic acid templated transcriptionGO:1903507530.075
sex differentiationGO:00075489090.074
regulation of biological qualityGO:00650087410.072
regulation of nitrogen compound metabolic processGO:00511712220.072
macromolecule localizationGO:00330367710.072
gene silencingGO:00164581430.070
regulation of neurogenesisGO:0050767400.069
negative regulation of vulval developmentGO:00400272060.069
protein metabolic processGO:00195384220.068
endocytosisGO:00068978190.068
cellular macromolecule biosynthetic processGO:00346452470.067
head developmentGO:006032210.067
negative regulation of metabolic processGO:00098922400.066
cell proliferationGO:00082831160.065
chromatin organizationGO:0006325320.065
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.065
negative regulation of cellular metabolic processGO:0031324950.064
ovipositionGO:00189913640.061
negative regulation of macromolecule metabolic processGO:00106052290.060
nervous system developmentGO:00073992530.060
reproductive structure developmentGO:00486088500.059
post embryonic organ developmentGO:00485693360.058
posttranscriptional regulation of gene expressionGO:00106081660.057
sexual reproductionGO:00199535460.055
response to organic substanceGO:00100331310.055
phosphorylationGO:00163101160.055
chromosome organizationGO:00512761040.054
single organism localizationGO:19025785180.054
macromolecular complex subunit organizationGO:00439333200.052
cellular response to organic substanceGO:00713101190.052
regulation of meiosisGO:0040020940.052
positive regulation of gene expressionGO:00106281120.052
multi organism behaviorGO:00517053890.051
regulation of nuclear divisionGO:00517831150.051
regulation of developmental growthGO:00486383890.051
maintenance of locationGO:00512355800.051
regulation of gene expression epigeneticGO:00400291630.051
lipid storageGO:00199155650.050
axon developmentGO:00615641630.050
regulation of multicellular organismal developmentGO:20000263170.049
reproductive behaviorGO:00190983870.049
organophosphate metabolic processGO:00196371250.048
regulation of cell divisionGO:00513021420.048
biosynthetic processGO:00090583230.048
development of primary sexual characteristicsGO:00451378400.047
cell deathGO:00082195470.047
protein localizationGO:00081042050.047
cell projection organizationGO:00300302310.046
neuron projection developmentGO:00311751870.046
cellular protein complex assemblyGO:00436231780.046
regulation of anatomical structure morphogenesisGO:0022603510.046
actin cytoskeleton organizationGO:00300361840.046
single organism catabolic processGO:00447121290.045
single organism organelle organizationGO:19025895010.045
regulation of cellular component biogenesisGO:0044087260.044
regulation of multicellular organism growthGO:00400143730.044
posttranscriptional gene silencingGO:00164411430.044
lipid localizationGO:00108765730.043
signal transductionGO:00071653170.043
Human
developmental process involved in reproductionGO:000300611650.043
multicellular organism growthGO:00352643850.041
single organism signalingGO:00447004010.041
Human
meiotic cell cycleGO:00513213350.040
determination of adult lifespanGO:00083408120.040
neuron differentiationGO:00301822170.040
vulval developmentGO:00400253330.040
reproductive system developmentGO:00614588500.040
cellular protein modification processGO:00064642070.039
regulation of cellular macromolecule biosynthetic processGO:20001121880.039
axon guidanceGO:0007411820.039
positive regulation of macromolecule biosynthetic processGO:00105571090.038
single organism reproductive processGO:004470211960.038
epidermis morphogenesisGO:004873070.038
cell motilityGO:00488703130.038
negative regulation of nematode larval developmentGO:00610642080.037
cell morphogenesis involved in differentiationGO:00009041120.037
posttranscriptional gene silencing by rnaGO:00351941430.037
transcription from rna polymerase ii promoterGO:00063661490.036
positive regulation of cell migrationGO:003033530.036
positive regulation of cellular processGO:00485223320.036
developmental growthGO:00485894120.036
positive regulation of cellular biosynthetic processGO:00313281090.035
negative regulation of nitrogen compound metabolic processGO:0051172630.035
programmed cell deathGO:00125015000.034
macromolecule biosynthetic processGO:00090592500.034
body morphogenesisGO:00101716200.034
multi organism reproductive behaviorGO:00447053870.034
innate immune responseGO:00450871900.033
cellular response to chemical stimulusGO:00708871290.033
positive regulation of metabolic processGO:00098931870.032
positive regulation of rna metabolic processGO:00512541030.032
defense responseGO:00069522960.032
organic substance biosynthetic processGO:19015763230.032
cell migrationGO:00164773060.031
dna recombinationGO:0006310190.031
positive regulation of developmental growthGO:00486393540.031
aromatic compound biosynthetic processGO:00194381920.031
nucleobase containing compound biosynthetic processGO:00346541840.030
cellular component movementGO:00069283880.030
axonogenesisGO:00074091020.030
positive regulation of multicellular organism growthGO:00400183520.030
regulation of cell communicationGO:00106461760.030
Human
ribonucleoside metabolic processGO:0009119980.030
negative regulation of nucleobase containing compound metabolic processGO:0045934630.029
negative regulation of multicellular organismal processGO:00512412360.029
peptidyl amino acid modificationGO:0018193580.029
negative regulation of gene expressionGO:00106292170.029
small molecule metabolic processGO:00442811860.029
heterocycle biosynthetic processGO:00181301870.029
cellular macromolecular complex assemblyGO:00346221840.028
protein modification processGO:00362112070.028
dna metabolic processGO:0006259740.028
nucleobase containing small molecule metabolic processGO:00550861150.028
neuron projection guidanceGO:0097485820.027
oocyte axis specificationGO:000730920.027
regulation of nematode larval developmentGO:00610622600.027
single organism biosynthetic processGO:0044711910.026
regulation of cellular biosynthetic processGO:00313261890.026
regulation of nucleobase containing compound metabolic processGO:00192192220.026
macromolecule modificationGO:00434122180.026
cell projection assemblyGO:0030031350.025
positive regulation of biosynthetic processGO:00098911090.025
protein complex assemblyGO:00064611860.025
gene silencing by rnaGO:00310471430.025
single organism behaviorGO:0044708830.024
negative regulation of rna biosynthetic processGO:1902679530.024
positive regulation of signalingGO:0023056660.024
cellular nitrogen compound biosynthetic processGO:00442711920.024
chromatin modificationGO:0016568320.024
response to abiotic stimulusGO:00096281520.023
immune responseGO:00069551920.023
female gamete generationGO:00072922540.023
regulation of post embryonic developmentGO:00485802600.023
negative regulation of macromolecule biosynthetic processGO:0010558650.023
protein complex biogenesisGO:00702711860.023
nucleobase containing compound catabolic processGO:00346551140.022
negative regulation of cellular biosynthetic processGO:0031327650.022
cellular process involved in reproduction in multicellular organismGO:00224123510.022
cellular component assembly involved in morphogenesisGO:00109271830.022
actin filament based processGO:00300291910.022
positive regulation of macromolecule metabolic processGO:00106041490.022
tissue morphogenesisGO:0048729650.022
rna metabolic processGO:00160702280.022
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.022
rna interferenceGO:00162461370.021
nucleoside triphosphate metabolic processGO:0009141870.021
meiotic chromosome segregationGO:00451321390.021
heterocycle catabolic processGO:00467001190.021
regulation of programmed cell deathGO:0043067500.020
organic cyclic compound catabolic processGO:19013611190.020
response to endogenous stimulusGO:0009719330.020
regulation of cell cycleGO:00517261940.020
cellular catabolic processGO:00442481990.020
regulation of response to stimulusGO:00485832430.020
Human
covalent chromatin modificationGO:0016569300.020
catabolic processGO:00090563180.020
negative regulation of programmed cell deathGO:0043069190.020
positive regulation of stress activated mapk cascadeGO:003287430.019
protein phosphorylationGO:0006468850.019
regulation of mitotic cell cycleGO:0007346760.019
neural precursor cell proliferationGO:006135190.019
rna localizationGO:000640330.019
regulation of biosynthetic processGO:00098891890.019
response to woundingGO:000961140.019
pole plasm assemblyGO:000731520.018
positive regulation of neurogenesisGO:005076940.018
anatomical structure formation involved in morphogenesisGO:00486462500.018
negative regulation of rna metabolic processGO:0051253530.018
proteolysisGO:0006508610.018
organic substance transportGO:00717021130.017
dna repairGO:0006281230.017
neuron apoptotic processGO:005140240.017
epithelium developmentGO:0060429680.017
negative regulation of apoptotic processGO:0043066170.017
cell cell signalingGO:00072671180.017
regulation of transcription dna templatedGO:00063551640.017
regulation of localizationGO:00328791940.017
regulation of apoptotic signaling pathwayGO:200123310.016
regionalizationGO:0003002310.016
cellular macromolecule localizationGO:0070727750.016
asymmetric protein localizationGO:0008105350.016
negative regulation of neurogenesisGO:005076840.016
aromatic compound catabolic processGO:00194391160.016
regulation of anatomical structure sizeGO:0090066460.016
regulation of molecular functionGO:0065009890.016
muscle cell differentiationGO:00426921710.016
cell fate commitmentGO:00451651390.016
negative regulation of transcription dna templatedGO:0045892530.016
gamete generationGO:00072764610.016
organelle assemblyGO:00709252140.016
positive regulation of epithelial cell proliferationGO:005067910.016
synapse organizationGO:0050808240.016
regulation of cellular protein metabolic processGO:0032268750.016
protein polymerizationGO:0051258260.016
regulation of epithelial cell proliferationGO:005067810.015
negative regulation of response to external stimulusGO:003210230.015
positive regulation of protein metabolic processGO:0051247450.015
regulation of cytoplasmic transportGO:190364930.014
regulation of cytoskeleton organizationGO:0051493410.014
defense response to other organismGO:00985421000.014
regenerationGO:003109940.014
carbohydrate derivative metabolic processGO:19011351410.014
regulation of synapse assemblyGO:005196320.014
nucleotide metabolic processGO:00091171080.014
macromolecular complex assemblyGO:00650031930.014
negative regulation of gene expression epigeneticGO:004581420.014
histone modificationGO:0016570300.014
ribonucleoside triphosphate catabolic processGO:0009203720.014
positive regulation of molecular functionGO:0044093610.014
positive regulation of nucleobase containing compound metabolic processGO:00459351340.014
negative regulation of cell cycleGO:0045786530.013
regulation of vulval developmentGO:00400282480.013
cellular response to stressGO:00335541620.013
striated muscle cell differentiationGO:00511461580.013
positive regulation of apoptotic processGO:0043065170.013
regulation of cell differentiationGO:0045595810.013
nucleic acid templated transcriptionGO:00976591690.013
positive regulation of nucleic acid templated transcriptionGO:19035081020.013
developmental inductionGO:003112810.013
cellular response to inorganic substanceGO:007124130.013
cellular amino acid metabolic processGO:0006520150.013
learning or memoryGO:0007611270.012
regulation of cell shapeGO:000836060.012
muscle structure developmentGO:00610611910.012
regulation of cell deathGO:0010941650.012
cytoskeleton organizationGO:00070103390.012
nucleoside phosphate metabolic processGO:00067531080.012
response to external stimulusGO:00096052890.012
purine nucleoside catabolic processGO:0006152750.012
regulation of signal transductionGO:00099661350.012
Human
secretion by cellGO:00329401380.012
carboxylic acid metabolic processGO:0019752340.012
establishment of organelle localizationGO:00516561230.012
regulation of nervous system developmentGO:0051960410.012
germ cell developmentGO:00072813510.012
synaptic growth at neuromuscular junctionGO:005112410.012
regulation of stem cell differentiationGO:200073610.012
cell growthGO:0016049440.012
lipid metabolic processGO:0006629770.012
negative regulation of cell communicationGO:0010648610.012
small gtpase mediated signal transductionGO:0007264320.012
neuroblast proliferationGO:000740590.012
regulation of meiotic cell cycleGO:00514451360.012
organelle localizationGO:00516401270.011
regulation of protein localizationGO:0032880500.011
chemotaxisGO:00069351200.011
regulation of signalingGO:00230511720.011
Human
intracellular signal transductionGO:0035556960.011
Human
regulation of cellular ketone metabolic processGO:001056530.011
neuromuscular processGO:005090510.011
response to fibroblast growth factorGO:007177450.011
developmental growth involved in morphogenesisGO:0060560370.011
muscle tissue developmentGO:006053710.011
epithelial cell proliferationGO:005067310.011
defense response to gram negative bacteriumGO:0050829640.011
oogenesisGO:00484772290.011
regulation of epithelial cell differentiationGO:003085640.011
positive regulation of cell communicationGO:0010647690.011
organic cyclic compound biosynthetic processGO:19013621950.011
regulation of reproductive processGO:2000241660.010
regulation of organ morphogenesisGO:200002740.010
cellular response to abiotic stimulusGO:007121440.010
regulation of cell developmentGO:0060284490.010
glycoprotein metabolic processGO:0009100290.010
regulation of rna metabolic processGO:00512521730.010
purine nucleoside monophosphate catabolic processGO:0009128280.010
cellular nitrogen compound catabolic processGO:00442701190.010
cell cycleGO:00070495260.010

clk-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.293
cancerDOID:16200.055
organ system cancerDOID:005068600.039
disease of anatomical entityDOID:700.025
colorectal cancerDOID:925600.024
intestinal cancerDOID:1015500.024
gastrointestinal system cancerDOID:311900.024
large intestine cancerDOID:567200.024