Caenorhabditis elegans

15 known processes

mec-12 (CELE_C44B11.3)

Protein MEC-12

mec-12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transportGO:000681010930.443
Worm
multi organism reproductive processGO:00447038670.374
Worm
embryo developmentGO:000979030520.364
Worm
sexual reproductionGO:00199535460.360
Worm
regulation of multicellular organismal processGO:00512397260.337
post embryonic developmentGO:000979121520.327
Worm
sex differentiationGO:00075489090.321
multicellular organism reproductionGO:00325048190.283
organ developmentGO:004851311020.239
cellular component movementGO:00069283880.220
Worm
gonad developmentGO:00084068400.207
hermaphrodite genitalia developmentGO:00400357340.204
reproductive system developmentGO:00614588500.197
reproductive structure developmentGO:00486088500.190
developmental process involved in reproductionGO:000300611650.186
positive regulation of developmental processGO:00510944080.181
neuron differentiationGO:00301822170.180
development of primary sexual characteristicsGO:00451378400.171
multi organism reproductive behaviorGO:00447053870.160
response to mechanical stimulusGO:0009612280.160
single organism behaviorGO:0044708830.159
negative regulation of biological processGO:00485195670.159
vesicle mediated transportGO:00161928520.149
Worm
receptor mediated endocytosisGO:00068987150.146
Worm
locomotionGO:004001116340.144
organic substance catabolic processGO:19015752940.144
cell developmentGO:00484686960.137
Zebrafish
macromolecule localizationGO:00330367710.130
Worm
regulation of metabolic processGO:00192224780.128
endocytosisGO:00068978190.128
Worm
macromolecule catabolic processGO:00090572020.126
response to chemicalGO:00422213560.125
protein catabolic processGO:00301631620.124
multicellular organismal reproductive processGO:00486098150.122
multi multicellular organism processGO:00447063900.122
regulation of biological qualityGO:00650087410.118
Zebrafish Worm
microtubule based processGO:00070171820.116
cellular component morphogenesisGO:00329893180.113
genitalia developmentGO:00488067410.111
ovipositionGO:00189913640.105
neurogenesisGO:00220082360.103
Zebrafish
neuron projection developmentGO:00311751870.098
behaviorGO:00076105270.098
body morphogenesisGO:00101716200.097
cell motilityGO:00488703130.096
Worm
cell projection organizationGO:00300302310.096
reproductive behaviorGO:00190983870.093
multicellular organism growthGO:00352643850.092
localization of cellGO:00516743130.092
Worm
positive regulation of developmental growthGO:00486393540.092
establishment of localization in cellGO:00516493180.090
Worm
organelle organizationGO:00069967830.090
Worm
cell cycle processGO:00224024820.086
Worm
multicellular organismal reproductive behaviorGO:00330573840.086
organelle localizationGO:00516401270.086
Worm
regulation of multicellular organism growthGO:00400143730.085
establishment of organelle localizationGO:00516561230.085
Worm
protein metabolic processGO:00195384220.083
regulation of developmental processGO:00507936840.083
positive regulation of multicellular organism growthGO:00400183520.083
regulation of gene expressionGO:00104683660.081
spindle organizationGO:0007051920.081
Worm
regulation of organelle organizationGO:00330431640.080
organelle fissionGO:00482853630.078
Worm
lipid storageGO:00199155650.078
Worm
female gamete generationGO:00072922540.077
establishment of localizationGO:005123411710.077
Worm
cellular component assembly involved in morphogenesisGO:00109271830.076
lipid localizationGO:00108765730.075
Worm
catabolic processGO:00090563180.073
embryo development ending in birth or egg hatchingGO:000979229920.072
Worm
mitotic spindle organizationGO:0007052810.072
Worm
gamete generationGO:00072764610.072
maintenance of locationGO:00512355800.071
Worm
positive regulation of multicellular organismal processGO:00512404170.071
organic cyclic compound biosynthetic processGO:19013621950.070
signalingGO:00230524010.067
Zebrafish
protein modification processGO:00362112070.066
negative regulation of multicellular organismal processGO:00512412360.063
cell migrationGO:00164773060.062
Worm
molting cycleGO:00423032810.062
axon developmentGO:00615641630.061
negative regulation of developmental processGO:00510932270.061
growthGO:00400075620.061
cellular component biogenesisGO:00440852970.059
regulation of growthGO:00400084090.057
gene expressionGO:00104674120.057
regulation of cellular biosynthetic processGO:00313261890.057
cellular localizationGO:00516413600.057
Worm
regulation of cellular macromolecule biosynthetic processGO:20001121880.055
generation of neuronsGO:00486992350.055
positive regulation of cellular processGO:00485223320.055
nucleobase containing compound metabolic processGO:00061394060.055
single organism transportGO:00447654470.055
positive regulation of growthGO:00459273690.054
multi organism behaviorGO:00517053890.054
single organism localizationGO:19025785180.054
Worm
response to external stimulusGO:00096052890.052
determination of adult lifespanGO:00083408120.052
Worm
positive regulation of cellular metabolic processGO:00313251780.052
molting cycle collagen and cuticulin based cuticleGO:00189962810.052
oogenesisGO:00484772290.051
positive regulation of macromolecule biosynthetic processGO:00105571090.051
tube developmentGO:00352951260.051
single organism reproductive processGO:004470211960.051
Worm
cytoskeleton organizationGO:00070103390.051
Worm
positive regulation of metabolic processGO:00098931870.050
aromatic compound biosynthetic processGO:00194381920.050
muscle organ morphogenesisGO:004864440.050
regulation of hydrolase activityGO:0051336450.048
agingGO:00075688120.048
Worm
organic substance biosynthetic processGO:19015763230.048
regulation of cellular component organizationGO:00511282480.048
cell cycleGO:00070495260.047
Worm
cellular component assemblyGO:00226072930.046
mechanosensory behaviorGO:0007638250.046
positive regulation of rna biosynthetic processGO:19026801020.046
developmental growthGO:00485894120.045
cellular nitrogen compound biosynthetic processGO:00442711920.045
single organism organelle organizationGO:19025895010.045
Worm
cellular biosynthetic processGO:00442493150.044
regulation of developmental growthGO:00486383890.043
phosphate containing compound metabolic processGO:00067962320.043
striated muscle cell developmentGO:00550021570.043
establishment of nucleus localizationGO:0040023550.042
Worm
neuron developmentGO:00486661990.042
regulation of cell communicationGO:00106461760.041
cellular macromolecule biosynthetic processGO:00346452470.041
cell deathGO:00082195470.040
Worm
regulation of locomotionGO:00400121610.040
regulation of macromolecule metabolic processGO:00602554210.039
negative regulation of gene expressionGO:00106292170.039
organonitrogen compound metabolic processGO:19015641510.039
response to biotic stimulusGO:00096071010.039
striated muscle cell differentiationGO:00511461580.038
muscle cell developmentGO:00550011580.038
response to bacteriumGO:0009617860.037
nucleobase containing compound biosynthetic processGO:00346541840.037
system processGO:00030081360.037
Zebrafish
cellular catabolic processGO:00442481990.036
nuclear migrationGO:0007097540.036
Worm
single organism signalingGO:00447004010.036
Zebrafish
macromolecular complex assemblyGO:00650031930.036
post embryonic organ developmentGO:00485693360.036
positive regulation of nitrogen compound metabolic processGO:00511731340.035
nervous system developmentGO:00073992530.035
Zebrafish
cellular process involved in reproduction in multicellular organismGO:00224123510.034
organic cyclic compound catabolic processGO:19013611190.034
response to abiotic stimulusGO:00096281520.033
eating behaviorGO:0042755590.033
regulation of nematode larval developmentGO:00610622600.033
biosynthetic processGO:00090583230.032
regulation of response to stimulusGO:00485832430.032
regulation of macromolecule biosynthetic processGO:00105561890.032
inductive cell migrationGO:00400391450.032
Worm
organelle assemblyGO:00709252140.032
striated muscle myosin thick filament assemblyGO:00716881380.031
response to other organismGO:00517071010.031
aromatic compound catabolic processGO:00194391160.030
positive regulation of cellular biosynthetic processGO:00313281090.030
cellular protein metabolic processGO:00442672790.030
muscle cell differentiationGO:00426921710.030
regulation of gene expression epigeneticGO:00400291630.030
head developmentGO:006032210.029
actin filament based processGO:00300291910.029
regulation of cytoskeleton organizationGO:0051493410.029
regulation of rna biosynthetic processGO:20011411650.029
anatomical structure formation involved in morphogenesisGO:00486462500.029
positive regulation of nucleobase containing compound metabolic processGO:00459351340.029
germ cell developmentGO:00072813510.029
cellular macromolecular complex assemblyGO:00346221840.029
protein complex assemblyGO:00064611860.028
regulation of signal transductionGO:00099661350.027
protein complex subunit organizationGO:00718222800.027
Worm
mitotic nuclear divisionGO:0007067890.027
Worm
small molecule metabolic processGO:00442811860.027
cell morphogenesisGO:00009021630.027
secretion by cellGO:00329401380.027
muscle structure developmentGO:00610611910.027
signal transductionGO:00071653170.027
regulation of cell differentiationGO:0045595810.027
multicellular organismal agingGO:00102598120.026
Worm
macromolecule modificationGO:00434122180.026
cellular protein modification processGO:00064642070.026
regulation of nitrogen compound metabolic processGO:00511712220.026
locomotory behaviorGO:0007626400.026
nucleic acid metabolic processGO:00903042990.026
myosin filament assemblyGO:00310341380.025
myosin filament organizationGO:00310331380.025
chromosome segregationGO:00070591800.025
organonitrogen compound catabolic processGO:1901565900.025
negative regulation of metabolic processGO:00098922400.025
positive regulation of nucleic acid templated transcriptionGO:19035081020.025
regulation of post embryonic developmentGO:00485802600.025
cell projection morphogenesisGO:00488581480.024
regulation of localizationGO:00328791940.024
regulation of cell cycleGO:00517261940.024
Worm
myofibril assemblyGO:00302391540.024
regulation of cell motilityGO:2000145570.024
regulation of actin filament based processGO:0032970220.024
spindle localizationGO:0051653510.023
Worm
cell divisionGO:00513012620.023
Worm
defense response to other organismGO:00985421000.023
cellular protein complex assemblyGO:00436231780.022
cellular nitrogen compound catabolic processGO:00442701190.022
deathGO:00162655470.022
Worm
negative regulation of cellular processGO:00485232390.022
pronuclear migrationGO:0035046510.022
Worm
protein localizationGO:00081042050.022
Worm
phosphorus metabolic processGO:00067932320.022
cell morphogenesis involved in differentiationGO:00009041120.022
meiotic cell cycleGO:00513213350.021
regulation of multicellular organismal developmentGO:20000263170.021
transcription dna templatedGO:00063511680.021
positive regulation of rna metabolic processGO:00512541030.021
single organism cellular localizationGO:1902580720.021
Worm
regulation of cellular metabolic processGO:00313233050.021
regulation of transcription from rna polymerase ii promoterGO:00063571450.021
nuclear pore distributionGO:003108120.020
cell part morphogenesisGO:00329901520.020
meiotic cell cycle processGO:19030461700.020
protein complex biogenesisGO:00702711860.020
posttranscriptional regulation of gene expressionGO:00106081660.020
chemotaxisGO:00069351200.020
epithelial tube morphogenesisGO:006056210.020
taxisGO:00423301280.020
chemosensory behaviorGO:0007635330.019
nucleobase containing compound catabolic processGO:00346551140.019
gene silencingGO:00164581430.019
programmed cell deathGO:00125015000.019
Worm
heterocycle catabolic processGO:00467001190.019
rna metabolic processGO:00160702280.018
membrane organizationGO:00610241350.018
regulation of nucleobase containing compound metabolic processGO:00192192220.018
positive regulation of biosynthetic processGO:00098911090.018
regulation of primary metabolic processGO:00800902920.018
meiotic nuclear divisionGO:00071263000.017
neuron recognitionGO:0008038830.017
response to external biotic stimulusGO:00432071010.017
positive regulation of gene expressionGO:00106281120.017
regulation of nucleotide catabolic processGO:0030811350.017
nucleic acid templated transcriptionGO:00976591690.017
secretionGO:00469031470.017
regulation of protein localizationGO:0032880500.017
regulation of reproductive processGO:2000241660.017
actomyosin structure organizationGO:00310321540.017
purine ribonucleotide metabolic processGO:0009150950.017
actin cytoskeleton organizationGO:00300361840.016
negative regulation of nematode larval developmentGO:00610642080.016
regulation of cell divisionGO:00513021420.016
Worm
macromolecular complex subunit organizationGO:00439333200.016
Worm
regulation of apoptotic signaling pathwayGO:200123310.016
synaptic vesicle endocytosisGO:004848830.016
regulation of rna metabolic processGO:00512521730.016
regulation of mitotic cell cycleGO:0007346760.016
regulation of cellular component movementGO:0051270620.016
defense response to bacteriumGO:0042742860.016
fertilizationGO:0009566630.016
Worm
negative regulation of macromolecule metabolic processGO:00106052290.015
regulation of atp catabolic processGO:190328930.015
mitotic cell cycle processGO:19030471940.015
Worm
establishment or maintenance of cell polarityGO:0007163630.015
Worm
feeding behaviorGO:0007631700.015
carboxylic acid metabolic processGO:0019752340.015
skeletal muscle organ developmentGO:006053830.015
negative regulation of gene expression epigeneticGO:004581420.015
tissue developmentGO:00098881120.014
male anatomical structure morphogenesisGO:0090598780.014
neuron projection morphogenesisGO:00488121140.014
regulation of feeding behaviorGO:0060259380.014
mitotic nuclear envelope reassemblyGO:000708430.014
response to organic substanceGO:00100331310.014
cell morphogenesis involved in neuron differentiationGO:00486671110.014
matingGO:0007618340.013
regulation of cell cycle processGO:00105641450.013
Worm
organic substance transportGO:00717021130.013
defense responseGO:00069522960.013
glycosyl compound metabolic processGO:19016571000.013
axonal fasciculationGO:0007413790.013
regulation of signalingGO:00230511720.013
regulation of epithelial cell differentiationGO:003085640.013
apoptotic processGO:00069154780.013
Worm
establishment of mitotic spindle localizationGO:0040001410.013
Worm
regulation of pharyngeal pumpingGO:0043051360.012
regulation of multi organism processGO:0043900690.012
mating behaviorGO:0007617320.012
posttranscriptional gene silencingGO:00164411430.012
regulation of cell migrationGO:0030334550.012
posttranscriptional gene silencing by rnaGO:00351941430.012
response to woundingGO:000961140.012
cell recognitionGO:0008037850.012
regulation of purine nucleotide catabolic processGO:0033121350.012
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.012
cell fate commitmentGO:00451651390.012
positive regulation of transcription dna templatedGO:00458931020.012
adult locomotory behaviorGO:000834410.012
regulation of cellular localizationGO:0060341420.012
lamellipodium assemblyGO:003003220.011
single organism catabolic processGO:00447121290.011
establishment of vesicle localizationGO:0051650230.011
adult behaviorGO:003053430.011
tube morphogenesisGO:0035239790.011
nucleoside metabolic processGO:0009116990.011
axonogenesisGO:00074091020.011
regulation of catalytic activityGO:0050790780.011
purine nucleotide catabolic processGO:0006195750.011
carbohydrate derivative metabolic processGO:19011351410.011
negative regulation of vulval developmentGO:00400272060.011
heterocycle biosynthetic processGO:00181301870.011
nucleobase containing small molecule metabolic processGO:00550861150.011
transcription from rna polymerase ii promoterGO:00063661490.011
inactivation of mapkkk activityGO:005139020.011
negative regulation of cation channel activityGO:200125820.011
detection of external stimulusGO:000958140.011
digestive system developmentGO:00551231220.011
purine nucleoside triphosphate catabolic processGO:0009146720.011
regulation of nucleic acid templated transcriptionGO:19035061650.010
regulation of phosphate metabolic processGO:0019220810.010
single organism intracellular transportGO:1902582700.010
organic acid metabolic processGO:0006082470.010
purine nucleoside metabolic processGO:0042278920.010
positive regulation of protein transportGO:005122240.010

mec-12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
muscular diseaseDOID:008000000.053
myopathyDOID:42300.053
muscle tissue diseaseDOID:6600.053
cardiomyopathyDOID:005070000.053
heart diseaseDOID:11400.053
cardiovascular system diseaseDOID:128700.053
musculoskeletal system diseaseDOID:1700.053
intrinsic cardiomyopathyDOID:006003600.029
dilated cardiomyopathyDOID:1293000.029
muscular dystrophyDOID:988400.022
congenital muscular dystrophyDOID:005055700.022
familial partial lipodystrophyDOID:005044000.021
integumentary system diseaseDOID:1600.021
skin diseaseDOID:3700.021
lipodystrophyDOID:81100.021
neuropathyDOID:87000.020
nervous system diseaseDOID:86300.020
neuromuscular diseaseDOID:44000.020
charcot marie tooth diseaseDOID:1059500.020
charcot marie tooth disease type 2DOID:005053900.020
progeriaDOID:391100.015
hypertrophic cardiomyopathyDOID:1198400.014
limb girdle muscular dystrophyDOID:1172400.011