Caenorhabditis elegans

59 known processes

dkf-2 (CELE_T25E12.4)

Protein DKF-2

dkf-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organ developmentGO:004851311020.375
transportGO:000681010930.338
Mouse
locomotionGO:004001116340.331
Human Worm
post embryonic developmentGO:000979121520.276
regulation of multicellular organismal processGO:00512397260.275
Human Mouse
establishment of localizationGO:005123411710.248
Mouse
cell developmentGO:00484686960.243
Human
multicellular organism reproductionGO:00325048190.243
regulation of developmental growthGO:00486383890.230
deathGO:00162655470.226
Human
synaptic transmissionGO:00072681060.221
multicellular organismal reproductive processGO:00486098150.220
embryo development ending in birth or egg hatchingGO:000979229920.220
single organism transportGO:00447654470.219
Mouse
negative regulation of biological processGO:00485195670.212
Human
regulation of developmental processGO:00507936840.207
Human Mouse
embryo developmentGO:000979030520.206
multi organism reproductive processGO:00447038670.205
growthGO:00400075620.203
developmental process involved in reproductionGO:000300611650.202
cellular localizationGO:00516413600.200
Mouse
single organism localizationGO:19025785180.191
Mouse
single organism signalingGO:00447004010.176
behaviorGO:00076105270.175
Human
sexual reproductionGO:00199535460.174
positive regulation of multicellular organismal processGO:00512404170.174
Human Mouse
developmental growthGO:00485894120.167
multicellular organism growthGO:00352643850.165
vesicle mediated transportGO:00161928520.165
Mouse
establishment of localization in cellGO:00516493180.161
Mouse
protein metabolic processGO:00195384220.160
gonad developmentGO:00084068400.159
organelle organizationGO:00069967830.159
Human
hermaphrodite genitalia developmentGO:00400357340.158
regulation of transcription dna templatedGO:00063551640.157
Human
single organism reproductive processGO:004470211960.156
gamete generationGO:00072764610.155
macromolecule modificationGO:00434122180.151
agingGO:00075688120.149
cell cell signalingGO:00072671180.143
positive regulation of developmental processGO:00510944080.142
Human Mouse
endocytosisGO:00068978190.142
regulation of multicellular organismal developmentGO:20000263170.142
Human
receptor mediated endocytosisGO:00068987150.140
regulation of growthGO:00400084090.137
regulation of biological qualityGO:00650087410.136
regulation of macromolecule metabolic processGO:00602554210.133
Human Mouse
post embryonic organ developmentGO:00485693360.133
positive regulation of developmental growthGO:00486393540.130
germ cell developmentGO:00072813510.129
reproductive system developmentGO:00614588500.127
determination of adult lifespanGO:00083408120.124
negative regulation of multicellular organismal processGO:00512412360.122
regulation of metabolic processGO:00192224780.121
Human Mouse
positive regulation of growthGO:00459273690.120
sex differentiationGO:00075489090.119
secretionGO:00469031470.116
nucleic acid metabolic processGO:00903042990.116
Human Mouse
multicellular organismal reproductive behaviorGO:00330573840.115
oogenesisGO:00484772290.115
multicellular organismal agingGO:00102598120.111
phosphate containing compound metabolic processGO:00067962320.111
regulation of multicellular organism growthGO:00400143730.111
programmed cell deathGO:00125015000.109
macromolecule localizationGO:00330367710.108
development of primary sexual characteristicsGO:00451378400.107
cellular process involved in reproduction in multicellular organismGO:00224123510.107
multi organism reproductive behaviorGO:00447053870.106
cell cycle processGO:00224024820.106
multi organism behaviorGO:00517053890.105
cytoskeleton organizationGO:00070103390.104
cell cycleGO:00070495260.103
regulation of cellular metabolic processGO:00313233050.103
Human Mouse
signalingGO:00230524010.102
positive regulation of multicellular organism growthGO:00400183520.101
nucleobase containing compound metabolic processGO:00061394060.099
Human Mouse
generation of neuronsGO:00486992350.097
Human
negative regulation of cellular processGO:00485232390.096
Human
protein modification processGO:00362112070.095
genitalia developmentGO:00488067410.094
reproductive behaviorGO:00190983870.093
multi multicellular organism processGO:00447063900.093
response to external stimulusGO:00096052890.092
reproductive structure developmentGO:00486088500.090
cell deathGO:00082195470.087
Human
nucleic acid templated transcriptionGO:00976591690.085
Human
female gamete generationGO:00072922540.085
biosynthetic processGO:00090583230.083
Human Mouse
cell motilityGO:00488703130.081
Human
ovipositionGO:00189913640.080
maintenance of locationGO:00512355800.077
ion transportGO:00068111130.077
cellular protein modification processGO:00064642070.076
regulation of primary metabolic processGO:00800902920.076
Human Mouse
apoptotic processGO:00069154780.075
axon developmentGO:00615641630.074
nervous system developmentGO:00073992530.074
Human
lipid localizationGO:00108765730.073
neurogenesisGO:00220082360.073
Human
g protein coupled receptor signaling pathwayGO:0007186460.070
regulation of nitrogen compound metabolic processGO:00511712220.070
Human Mouse
lipid storageGO:00199155650.069
heterocycle biosynthetic processGO:00181301870.069
Human Mouse
negative regulation of developmental processGO:00510932270.068
negative regulation of macromolecule metabolic processGO:00106052290.067
phosphorus metabolic processGO:00067932320.067
regulation of post embryonic developmentGO:00485802600.067
cellular macromolecule biosynthetic processGO:00346452470.067
Human Mouse
regulation of macromolecule biosynthetic processGO:00105561890.066
Human Mouse
negative regulation of metabolic processGO:00098922400.064
intracellular signal transductionGO:0035556960.064
response to abiotic stimulusGO:00096281520.064
transcription dna templatedGO:00063511680.064
Human
vulval developmentGO:00400253330.063
cellular component movementGO:00069283880.062
Human
regulation of nucleobase containing compound metabolic processGO:00192192220.062
Human Mouse
ion transmembrane transportGO:0034220910.061
regulation of cellular component organizationGO:00511282480.061
Human
regulation of transcription from rna polymerase ii promoterGO:00063571450.060
Human
anatomical structure formation involved in morphogenesisGO:00486462500.060
Human
gene expressionGO:00104674120.059
Human
positive regulation of rna biosynthetic processGO:19026801020.058
Human
protein complex subunit organizationGO:00718222800.058
transmembrane transportGO:00550851100.057
calcium mediated signalingGO:001972230.057
regulation of response to stimulusGO:00485832430.055
regulation of locomotionGO:00400121610.055
Human
regulation of rna metabolic processGO:00512521730.055
Human
cellular biosynthetic processGO:00442493150.054
Human Mouse
regulation of neurotransmitter levelsGO:0001505360.054
cell surface receptor signaling pathwayGO:00071661490.054
Human Mouse
signal transductionGO:00071653170.054
regulation of nematode larval developmentGO:00610622600.053
body morphogenesisGO:00101716200.053
neuron differentiationGO:00301822170.052
Human
cellular nitrogen compound biosynthetic processGO:00442711920.052
Human Mouse
transcription from rna polymerase ii promoterGO:00063661490.052
Human
regulation of transportGO:0051049910.051
protein phosphorylationGO:0006468850.051
cellular protein metabolic processGO:00442672790.050
protein localizationGO:00081042050.049
positive regulation of biosynthetic processGO:00098911090.048
Human Mouse
organic substance biosynthetic processGO:19015763230.048
Human Mouse
cellular component biogenesisGO:00440852970.048
cellular protein localizationGO:0034613750.048
organelle fissionGO:00482853630.048
intracellular transportGO:0046907770.048
Mouse
embryonic morphogenesisGO:00485981520.048
response to chemicalGO:00422213560.047
Human
macromolecule biosynthetic processGO:00090592500.047
Human Mouse
regulation of biosynthetic processGO:00098891890.046
Human Mouse
cell migrationGO:00164773060.046
Human
secretion by cellGO:00329401380.046
cation transportGO:0006812780.046
organic cyclic compound biosynthetic processGO:19013621950.045
Human Mouse
nucleobase containing compound biosynthetic processGO:00346541840.045
Human Mouse
regulation of vulval developmentGO:00400282480.043
macromolecule catabolic processGO:00090572020.043
phosphorylationGO:00163101160.043
regulation of gene expressionGO:00104683660.043
Human
negative regulation of cellular metabolic processGO:0031324950.042
regulation of cellular biosynthetic processGO:00313261890.042
Human Mouse
single organism organelle organizationGO:19025895010.042
Human
single organism behaviorGO:0044708830.042
positive regulation of nucleobase containing compound metabolic processGO:00459351340.041
Human Mouse
axon guidanceGO:0007411820.041
regulation of catalytic activityGO:0050790780.041
Human
cell proliferationGO:00082831160.040
Human Mouse
cell projection organizationGO:00300302310.040
Human
regulation of signalingGO:00230511720.040
Human Mouse
regulation of synaptic transmissionGO:0050804340.039
aromatic compound biosynthetic processGO:00194381920.039
Human Mouse
feeding behaviorGO:0007631700.038
actomyosin structure organizationGO:00310321540.038
negative regulation of gene expressionGO:00106292170.037
positive regulation of cellular metabolic processGO:00313251780.037
Human Mouse
regulation of phosphorus metabolic processGO:0051174810.037
Human Mouse
regulation of localizationGO:00328791940.037
Human
regulation of nucleic acid templated transcriptionGO:19035061650.036
Human
cellular component morphogenesisGO:00329893180.036
meiotic cell cycleGO:00513213350.036
cell divisionGO:00513012620.036
protein complex assemblyGO:00064611860.036
protein catabolic processGO:00301631620.036
negative regulation of vulval developmentGO:00400272060.035
actin filament based processGO:00300291910.035
taxisGO:00423301280.035
Human
negative regulation of post embryonic developmentGO:00485812080.035
catabolic processGO:00090563180.035
actin cytoskeleton organizationGO:00300361840.035
neuron projection developmentGO:00311751870.034
Human
positive regulation of signalingGO:0023056660.034
Human Mouse
memoryGO:000761330.034
single organism intracellular transportGO:1902582700.034
Mouse
positive regulation of cellular processGO:00485223320.033
Human Mouse
striated muscle cell differentiationGO:00511461580.033
cellular protein complex assemblyGO:00436231780.033
cellular component assemblyGO:00226072930.033
macromolecular complex subunit organizationGO:00439333200.033
Human
head developmentGO:006032210.033
localization of cellGO:00516743130.033
Human
rna biosynthetic processGO:00327741690.032
Human
macromolecular complex assemblyGO:00650031930.032
muscle cell differentiationGO:00426921710.032
muscle cell developmentGO:00550011580.032
muscle structure developmentGO:00610611910.032
regulation of organelle organizationGO:00330431640.031
Human
positive regulation of response to stimulusGO:0048584550.031
negative regulation of nematode larval developmentGO:00610642080.030
rna metabolic processGO:00160702280.030
Human
positive regulation of nitrogen compound metabolic processGO:00511731340.030
Human Mouse
organelle assemblyGO:00709252140.030
adult behaviorGO:003053430.029
positive regulation of metabolic processGO:00098931870.029
Human Mouse
striated muscle myosin thick filament assemblyGO:00716881380.029
molting cycle collagen and cuticulin based cuticleGO:00189962810.029
dauer larval developmentGO:0040024920.029
signal transduction by phosphorylationGO:0023014310.029
Mouse
locomotory behaviorGO:0007626400.028
small molecule metabolic processGO:00442811860.028
regulation of molecular functionGO:0065009890.028
Human
molting cycleGO:00423032810.028
membrane organizationGO:00610241350.028
synaptic vesicle transportGO:0048489210.028
cell fate commitmentGO:00451651390.028
regulation of cell communicationGO:00106461760.028
Human Mouse
cellular response to stressGO:00335541620.027
Human
positive regulation of epithelial cell proliferationGO:005067910.027
Human
striated muscle cell developmentGO:00550021570.027
organelle localizationGO:00516401270.027
regulation of rna biosynthetic processGO:20011411650.027
Human
protein complex biogenesisGO:00702711860.026
organic substance transportGO:00717021130.026
organonitrogen compound metabolic processGO:19015641510.026
regulation of cytoplasmic transportGO:190364930.026
chemotaxisGO:00069351200.026
Human
negative regulation of cell communicationGO:0010648610.026
meiotic nuclear divisionGO:00071263000.025
sensory organ morphogenesisGO:009059620.025
response to inorganic substanceGO:0010035500.025
myofibril assemblyGO:00302391540.025
cell type specific apoptotic processGO:009728540.025
regulation of feeding behaviorGO:0060259380.025
positive regulation of nucleic acid templated transcriptionGO:19035081020.025
Human
positive regulation of cell communicationGO:0010647690.025
Human Mouse
regulation of meiotic cell cycleGO:00514451360.024
positive regulation of catalytic activityGO:0043085590.024
Human
organic substance catabolic processGO:19015752940.024
regulation of cell deathGO:0010941650.023
Human
positive regulation of gene expressionGO:00106281120.023
Human
regulation of multi organism processGO:0043900690.023
regulation of cell cycleGO:00517261940.023
inductive cell migrationGO:00400391450.023
cellular response to organic substanceGO:00713101190.023
Human
regulation of behaviorGO:0050795970.022
Human
muscle tissue developmentGO:006053710.022
mapk cascadeGO:0000165310.022
Mouse
establishment of organelle localizationGO:00516561230.022
organic acid metabolic processGO:0006082470.022
system processGO:00030081360.022
regulation of reproductive processGO:2000241660.022
axonogenesisGO:00074091020.022
positive regulation of rna metabolic processGO:00512541030.022
Human
eating behaviorGO:0042755590.021
regulation of neurotransmitter secretionGO:0046928160.021
microtubule based processGO:00070171820.021
cellular macromolecular complex assemblyGO:00346221840.021
cell recognitionGO:0008037850.021
cellular component assembly involved in morphogenesisGO:00109271830.021
negative regulation of macromolecule biosynthetic processGO:0010558650.021
neurotransmitter transportGO:0006836320.020
regulation of protein metabolic processGO:0051246810.020
Human
regulation of phosphorylationGO:0042325450.020
Human Mouse
regulation of cell cycle processGO:00105641450.020
immune responseGO:00069551920.020
regulation of cellular macromolecule biosynthetic processGO:20001121880.020
Human Mouse
ribosome biogenesisGO:004225440.020
regulation of epithelial cell proliferationGO:005067810.019
Human Mouse
neuron projection guidanceGO:0097485820.019
cell part morphogenesisGO:00329901520.019
male sex differentiationGO:0046661860.019
mitotic cell cycle processGO:19030471940.019
negative regulation of response to stimulusGO:0048585730.019
response to other organismGO:00517071010.019
oxoacid metabolic processGO:0043436470.019
regulation of pharyngeal pumpingGO:0043051360.019
nitrogen compound transportGO:0071705490.019
cellular response to chemical stimulusGO:00708871290.019
Human
neurological system processGO:0050877530.018
adult locomotory behaviorGO:000834410.018
positive regulation of neuron projection developmentGO:001097640.018
Human
defense responseGO:00069522960.018
epithelial cell proliferationGO:005067310.018
Human Mouse
cell projection morphogenesisGO:00488581480.018
male anatomical structure morphogenesisGO:0090598780.018
cellular catabolic processGO:00442481990.018
carbohydrate derivative metabolic processGO:19011351410.018
muscle system processGO:0003012430.018
neuron recognitionGO:0008038830.018
regulation of cellular protein metabolic processGO:0032268750.018
Human
tissue developmentGO:00098881120.018
regulation of ion transportGO:0043269390.017
myosin filament assemblyGO:00310341380.017
neuron developmentGO:00486661990.017
Human
neurotransmitter secretionGO:0007269260.017
neuromuscular junction developmentGO:000752820.017
negative regulation of neurogenesisGO:005076840.017
regulation of sequence specific dna binding transcription factor activityGO:005109030.017
Human
myosin filament organizationGO:00310331380.017
regulation of secretionGO:0051046290.017
response to woundingGO:000961140.017
acetate ester metabolic processGO:190061940.017
cell morphogenesis involved in differentiationGO:00009041120.017
positive regulation of vulval developmentGO:0040026520.017
regulation of nucleocytoplasmic transportGO:004682230.016
regulation of cell differentiationGO:0045595810.016
Human Mouse
synaptic vesicle endocytosisGO:004848830.016
negative regulation of biosynthetic processGO:0009890650.016
positive regulation of macromolecule metabolic processGO:00106041490.016
Human Mouse
cellular macromolecule localizationGO:0070727750.016
positive regulation of neurogenesisGO:005076940.016
Human
regulation of intracellular signal transductionGO:1902531770.016
Human Mouse
pharyngeal pumpingGO:0043050580.016
purine ribonucleotide metabolic processGO:0009150950.015
regulation of g protein coupled receptor protein signaling pathwayGO:000827740.015
regulation of phosphate metabolic processGO:0019220810.015
Human Mouse
regulation of cell motilityGO:2000145570.015
Human
regulation of nuclear divisionGO:00517831150.015
establishment of vesicle localizationGO:0051650230.015
regulation of cell developmentGO:0060284490.015
Human
cyclic nucleotide biosynthetic processGO:000919020.015
negative regulation of nitrogen compound metabolic processGO:0051172630.015
response to external biotic stimulusGO:00432071010.015
regulation of cell divisionGO:00513021420.015
rrna processingGO:000636430.015
regulation of lipid biosynthetic processGO:004689010.015
positive regulation of cellular biosynthetic processGO:00313281090.015
Human Mouse
negative regulation of transcription dna templatedGO:0045892530.014
organophosphate metabolic processGO:00196371250.014
gene silencing by rnaGO:00310471430.014
negative regulation of signalingGO:0023057610.014
regulation of response to woundingGO:190303410.014
metal ion transportGO:0030001490.014
regulation of protein targetingGO:190353330.014
synaptic vesicle localizationGO:0097479220.014
membrane depolarizationGO:005189910.014
cell morphogenesis involved in neuron differentiationGO:00486671110.014
axonal fasciculationGO:0007413790.014
positive regulation of cell morphogenesis involved in differentiationGO:001077040.014
regulation of signal transductionGO:00099661350.014
Human Mouse
canonical wnt signaling pathwayGO:006007030.014
regulation of cellular ketone metabolic processGO:001056530.014
homeostatic processGO:0042592510.014
signal releaseGO:0023061280.014
regulation of cell migrationGO:0030334550.014
Human
regenerationGO:003109940.013
response to organic substanceGO:00100331310.013
Human
regulation of synapse assemblyGO:005196320.013
protein localization to organelleGO:0033365370.013
rna interferenceGO:00162461370.013
ribonucleotide metabolic processGO:0009259990.013
negative regulation of ion transmembrane transportGO:003476630.013
positive regulation of intracellular transportGO:003238820.013
negative regulation of signal transductionGO:0009968600.013
cell fate commitment involved in formation of primary germ layerGO:0060795330.013
regulation of protein import into nucleusGO:004230630.013
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.013
Human
regulation of cellular component movementGO:0051270620.013
Human
epithelial tube morphogenesisGO:006056210.013
regulation of system processGO:0044057270.013
cellular amino acid metabolic processGO:0006520150.013
regulation of vesicle mediated transportGO:0060627270.013
regulation of protein localizationGO:0032880500.013
negative regulation of cellular biosynthetic processGO:0031327650.013
oocyte developmentGO:0048599440.012
vesicle localizationGO:0051648240.012
regulation of mapk cascadeGO:0043408230.012
Mouse
positive regulation of macromolecule biosynthetic processGO:00105571090.012
Human Mouse
regulation of cell proliferationGO:00421271050.012
Human Mouse
cell growthGO:0016049440.012
regulation of secretion by cellGO:1903530210.012
regulation of synaptic plasticityGO:004816710.012
carboxylic acid metabolic processGO:0019752340.012
excretionGO:0007588490.012
nucleoside phosphate metabolic processGO:00067531080.012
cuticle developmentGO:00423351000.012
detection of external stimulusGO:000958140.012
cellular ketone metabolic processGO:0042180140.012
response to mechanical stimulusGO:0009612280.012
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.012
posttranscriptional gene silencing by rnaGO:00351941430.012
apoptotic cell clearanceGO:00432771110.012
regulation of gene expression epigeneticGO:00400291630.012
protein oligomerizationGO:005125940.012
regulation of apoptotic signaling pathwayGO:200123310.012
regulation of mitotic cell cycleGO:0007346760.012
positive regulation of post embryonic developmentGO:0048582540.012
regulation of epithelial cell differentiationGO:003085640.012
single organism catabolic processGO:00447121290.012
positive regulation of phosphorus metabolic processGO:0010562560.012
Human Mouse
regulation of lipid metabolic processGO:001921640.011
anion transportGO:0006820300.011
peptidyl tyrosine phosphorylationGO:001810820.011
synaptic vesicle recyclingGO:003646530.011
motor neuron axon guidanceGO:0008045130.011
positive regulation of cell projection organizationGO:003134640.011
Human
dendrite developmentGO:0016358420.011
positive regulation of cell migrationGO:003033530.011
Human
negative regulation of transporter activityGO:003241030.011
regulation of organ morphogenesisGO:200002740.011
digestive system developmentGO:00551231220.011
response to endogenous stimulusGO:0009719330.011
Human
response to bacteriumGO:0009617860.011
acetylcholine metabolic processGO:000829140.011
nematode male tail tip morphogenesisGO:0045138770.011
synaptic growth at neuromuscular junctionGO:005112410.011
neuron projection morphogenesisGO:00488121140.011
actin cytoskeleton reorganizationGO:003153240.011
regulation of cellular amine metabolic processGO:003323800.011
negative regulation of cellular protein metabolic processGO:0032269270.011
regulation of cellular amino acid metabolic processGO:000652100.011
regulation of neuron differentiationGO:0045664400.011
Human
positive regulation of phosphate metabolic processGO:0045937560.011
Human Mouse
regulation of cellular localizationGO:0060341420.011
positive regulation of locomotionGO:0040017420.011
Human
nucleobase containing small molecule metabolic processGO:00550861150.011
neuromuscular processGO:005090510.011
amine metabolic processGO:0009308150.011
nucleotide metabolic processGO:00091171080.011
engulfment of apoptotic cellGO:0043652940.011
establishment of protein localization to membraneGO:009015030.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.011
sensory perceptionGO:0007600270.011
single organism biosynthetic processGO:0044711910.011
neuron apoptotic processGO:005140240.010
positive regulation of protein transportGO:005122240.010
defense response to other organismGO:00985421000.010
posttranscriptional regulation of gene expressionGO:00106081660.010
positive regulation of transcription dna templatedGO:00458931020.010
Human
lipid metabolic processGO:0006629770.010
collagen and cuticulin based cuticle developmentGO:0040002990.010
calcium ion transportGO:0006816160.010
single organism cellular localizationGO:1902580720.010
regulation of protein kinase activityGO:0045859280.010
regulation of meiosisGO:0040020940.010
negative regulation of neuron differentiationGO:004566540.010
spindle organizationGO:0007051920.010
oocyte differentiationGO:0009994450.010
rrna metabolic processGO:001607230.010
neuron neuron synaptic transmissionGO:0007270220.010
negative regulation of molecular functionGO:0044092200.010

dkf-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
organ system cancerDOID:005068600.012
nervous system diseaseDOID:86300.012