Caenorhabditis elegans

24 known processes

unc-68 (CELE_K11C4.5)

Protein UNC-68

unc-68 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.862
embryo developmentGO:000979030520.606
Mouse
endocytosisGO:00068978190.557
single organism organelle organizationGO:19025895010.542
skeletal muscle organ developmentGO:006053830.536
Mouse
regulation of developmental processGO:00507936840.472
Fly
protein complex subunit organizationGO:00718222800.465
vesicle mediated transportGO:00161928520.437
post embryonic developmentGO:000979121520.421
cell deathGO:00082195470.380
growthGO:00400075620.361
organelle organizationGO:00069967830.360
organ developmentGO:004851311020.343
Mouse
regulation of growthGO:00400084090.332
cell substrate adhesionGO:003158910.287
single organism reproductive processGO:004470211960.280
axonal defasciculationGO:000741410.279
cellular component biogenesisGO:00440852970.271
organelle assemblyGO:00709252140.262
positive regulation of multicellular organismal processGO:00512404170.258
Mouse
multicellular organismal reproductive processGO:00486098150.256
sarcomere organizationGO:0045214100.251
positive regulation of locomotionGO:0040017420.238
cell cycle processGO:00224024820.237
protein complex biogenesisGO:00702711860.230
membrane organizationGO:00610241350.227
regulation of developmental growthGO:00486383890.225
determination of adult lifespanGO:00083408120.222
macromolecular complex subunit organizationGO:00439333200.215
muscle tissue developmentGO:006053710.213
Mouse
regulation of multicellular organismal processGO:00512397260.212
Mouse Fly
developmental growthGO:00485894120.207
transportGO:000681010930.205
Zebrafish Mouse
organic substance catabolic processGO:19015752940.201
developmental process involved in reproductionGO:000300611650.190
regulation of synapse assemblyGO:005196320.185
integrin mediated signaling pathwayGO:000722910.184
deathGO:00162655470.183
post embryonic organ developmentGO:00485693360.180
synaptic vesicle endocytosisGO:004848830.179
multicellular organism reproductionGO:00325048190.174
cell cycleGO:00070495260.169
signalingGO:00230524010.167
Mouse
cellular component movementGO:00069283880.166
locomotionGO:004001116340.166
cellular component assembly involved in morphogenesisGO:00109271830.165
body morphogenesisGO:00101716200.158
ion transportGO:00068111130.157
Zebrafish Mouse
cell projection assemblyGO:0030031350.157
positive regulation of developmental processGO:00510944080.155
cilium organizationGO:0044782320.154
multicellular organism growthGO:00352643850.154
cellular component assemblyGO:00226072930.149
sex differentiationGO:00075489090.147
regulation of multicellular organismal developmentGO:20000263170.145
muscle organ developmentGO:0007517260.142
Mouse
sexual reproductionGO:00199535460.137
positive regulation of developmental growthGO:00486393540.137
establishment of localizationGO:005123411710.134
Zebrafish Mouse
receptor mediated endocytosisGO:00068987150.129
programmed cell deathGO:00125015000.129
response to external stimulusGO:00096052890.129
cytoskeleton organizationGO:00070103390.128
regulation of vulval developmentGO:00400282480.128
cell projection organizationGO:00300302310.126
gamete generationGO:00072764610.124
defense responseGO:00069522960.120
female gamete generationGO:00072922540.120
cell developmentGO:00484686960.119
Mouse
single organism signalingGO:00447004010.119
Mouse
positive regulation of multicellular organism growthGO:00400183520.117
agingGO:00075688120.116
actomyosin structure organizationGO:00310321540.116
regulation of post embryonic developmentGO:00485802600.114
gonad developmentGO:00084068400.114
macromolecule catabolic processGO:00090572020.114
response to abiotic stimulusGO:00096281520.111
Mouse
macromolecular complex assemblyGO:00650031930.110
myofibril assemblyGO:00302391540.110
muscle cell developmentGO:00550011580.110
Mouse
regulation of locomotionGO:00400121610.108
anatomical structure formation involved in morphogenesisGO:00486462500.103
multicellular organismal agingGO:00102598120.103
regulation of multicellular organism growthGO:00400143730.102
cellular process involved in reproduction in multicellular organismGO:00224123510.099
response to woundingGO:000961140.099
striated muscle cell differentiationGO:00511461580.099
Mouse
head developmentGO:006032210.097
defense response to other organismGO:00985421000.097
cellular macromolecular complex assemblyGO:00346221840.097
apoptotic processGO:00069154780.096
Mouse
regulation of nematode larval developmentGO:00610622600.096
multi organism behaviorGO:00517053890.094
regulation of biological qualityGO:00650087410.094
Mouse
muscle attachmentGO:001620330.092
molting cycle collagen and cuticulin based cuticleGO:00189962810.092
regulation of filopodium assemblyGO:005148920.092
muscle structure developmentGO:00610611910.092
Mouse
protein metabolic processGO:00195384220.091
organonitrogen compound metabolic processGO:19015641510.090
striated muscle cell developmentGO:00550021570.086
Mouse
ovipositionGO:00189913640.084
cell part morphogenesisGO:00329901520.081
catabolic processGO:00090563180.080
organelle fissionGO:00482853630.080
multi organism reproductive processGO:00447038670.078
cellular component morphogenesisGO:00329893180.077
divalent metal ion transportGO:0070838170.077
Zebrafish Mouse
cellular localizationGO:00516413600.076
muscle system processGO:0003012430.076
Zebrafish Mouse Fly
actin cytoskeleton organizationGO:00300361840.076
single organism transportGO:00447654470.075
Zebrafish Mouse
macromolecule localizationGO:00330367710.075
response to external biotic stimulusGO:00432071010.075
positive regulation of growthGO:00459273690.075
meiotic cell cycleGO:00513213350.075
negative regulation of nematode larval developmentGO:00610642080.073
neurological system processGO:0050877530.073
protein localization to basolateral plasma membraneGO:190336170.072
cell projection morphogenesisGO:00488581480.071
localization of cellGO:00516743130.070
reproductive structure developmentGO:00486088500.069
negative regulation of biological processGO:00485195670.069
Mouse
genitalia developmentGO:00488067410.065
negative regulation of post embryonic developmentGO:00485812080.065
reproductive behaviorGO:00190983870.064
regulation of rna biosynthetic processGO:20011411650.062
Mouse
actin filament based processGO:00300291910.062
reproductive system developmentGO:00614588500.062
regulation of actin filament based processGO:0032970220.062
Mouse
regulation of nucleoside metabolic processGO:0009118370.060
behaviorGO:00076105270.059
Zebrafish
cell matrix adhesionGO:000716010.058
inductive cell migrationGO:00400391450.057
organic substance transportGO:00717021130.056
cellular protein complex assemblyGO:00436231780.056
response to biotic stimulusGO:00096071010.055
response to chemicalGO:00422213560.055
Zebrafish Mouse Fly
regulation of cell projection assemblyGO:006049130.055
cellular response to organic substanceGO:00713101190.055
Mouse
organ morphogenesisGO:0009887670.053
Mouse
axon guidanceGO:0007411820.053
defense response to bacteriumGO:0042742860.053
regulation of cellular metabolic processGO:00313233050.052
Mouse
response to other organismGO:00517071010.052
cellular biosynthetic processGO:00442493150.052
Mouse
multicellular organismal reproductive behaviorGO:00330573840.051
regulation of cellular component organizationGO:00511282480.051
hermaphrodite genitalia developmentGO:00400357340.049
meiotic nuclear divisionGO:00071263000.048
lipid localizationGO:00108765730.048
cation transportGO:0006812780.046
Zebrafish Mouse
maintenance of locationGO:00512355800.045
Mouse
negative regulation of vulval developmentGO:00400272060.045
regulation of gene expression epigeneticGO:00400291630.045
rna localizationGO:000640330.044
regulation of nitrogen compound metabolic processGO:00511712220.044
Mouse
cellular catabolic processGO:00442481990.041
response to endogenous stimulusGO:0009719330.041
Mouse
positive regulation of cellular processGO:00485223320.040
protein complex assemblyGO:00064611860.040
embryonic body morphogenesisGO:0010172490.039
lipid storageGO:00199155650.039
immune responseGO:00069551920.039
regulation of cell cell adhesionGO:002240710.038
microtubule based processGO:00070171820.038
apoptotic cell clearanceGO:00432771110.037
muscle cell differentiationGO:00426921710.037
Mouse
development of primary sexual characteristicsGO:00451378400.037
positive regulation of molecular functionGO:0044093610.036
Mouse
molting cycleGO:00423032810.036
carbohydrate derivative metabolic processGO:19011351410.036
establishment of localization in cellGO:00516493180.036
Mouse
negative regulation of cellular processGO:00485232390.035
Mouse
mesodermal cell migrationGO:000807890.035
fertilizationGO:0009566630.035
nucleobase containing compound metabolic processGO:00061394060.035
Mouse
germ cell developmentGO:00072813510.035
regulation of cellular component biogenesisGO:0044087260.035
ribonucleoside metabolic processGO:0009119980.034
neurogenesisGO:00220082360.034
cilium assemblyGO:0042384280.034
single organism localizationGO:19025785180.034
Zebrafish Mouse
regulation of cytoskeleton organizationGO:0051493410.034
actin filament organizationGO:0007015210.034
myosin filament assemblyGO:00310341380.033
small molecule metabolic processGO:00442811860.032
cell morphogenesis involved in differentiationGO:00009041120.032
purine ribonucleotide metabolic processGO:0009150950.032
negative regulation of developmental processGO:00510932270.031
positive regulation of catalytic activityGO:0043085590.031
regulation of lamellipodium organizationGO:190274310.031
aromatic compound catabolic processGO:00194391160.030
cell migrationGO:00164773060.030
synapse organizationGO:0050808240.030
regulation of anatomical structure sizeGO:0090066460.030
lamellipodium assemblyGO:003003220.030
regulation of organelle organizationGO:00330431640.029
cellular protein metabolic processGO:00442672790.029
cellular response to chemical stimulusGO:00708871290.029
Zebrafish Mouse
filopodium assemblyGO:004684720.029
protein catabolic processGO:00301631620.029
dorsal ventral axon guidanceGO:0033563190.029
regulation of response to stimulusGO:00485832430.029
regulation of nervous system developmentGO:0051960410.028
memoryGO:000761330.028
ribonucleoside triphosphate metabolic processGO:0009199870.028
regulation of cell projection organizationGO:0031344380.028
organelle localizationGO:00516401270.028
digestive system developmentGO:00551231220.028
establishment of organelle localizationGO:00516561230.027
synaptic vesicle recyclingGO:003646530.026
macromolecule biosynthetic processGO:00090592500.026
Mouse
striated muscle myosin thick filament assemblyGO:00716881380.026
nucleobase containing small molecule metabolic processGO:00550861150.026
motor neuron axon guidanceGO:0008045130.026
heterocycle catabolic processGO:00467001190.026
protein localizationGO:00081042050.025
neuron developmentGO:00486661990.025
cell type specific apoptotic processGO:009728540.025
Mouse
regulation of signal transductionGO:00099661350.024
neuron projection guidanceGO:0097485820.024
organophosphate metabolic processGO:00196371250.024
establishment of protein localization to membraneGO:009015030.024
nucleotide metabolic processGO:00091171080.024
actin filament based movementGO:003004840.024
positive regulation of cell migrationGO:003033530.023
regulation of multi organism processGO:0043900690.023
positive regulation of nucleotide catabolic processGO:0030813280.023
ribonucleotide catabolic processGO:0009261750.023
actin filament bundle assemblyGO:005101730.023
cell surface receptor signaling pathwayGO:00071661490.023
Mouse
regulation of molecular functionGO:0065009890.023
Mouse
protein polymerizationGO:0051258260.022
biosynthetic processGO:00090583230.022
Mouse
protein modification processGO:00362112070.022
regulation of phagocytosis engulfmentGO:0060099170.022
skeletal muscle thin filament assemblyGO:003024030.022
posttranscriptional gene silencingGO:00164411430.021
cell divisionGO:00513012620.021
neuromuscular junction developmentGO:000752820.021
organic substance biosynthetic processGO:19015763230.021
Mouse
generation of neuronsGO:00486992350.021
mitotic cell cycle processGO:19030471940.021
epithelial tube morphogenesisGO:006056210.021
Mouse
myosin filament organizationGO:00310331380.021
cell motilityGO:00488703130.020
purine ribonucleoside triphosphate metabolic processGO:0009205870.020
regulation of cell proliferationGO:00421271050.020
Fly
meiotic cell cycle processGO:19030461700.020
synaptic growth at neuromuscular junctionGO:005112410.020
regulation of cell morphogenesisGO:0022604400.020
anatomical structure homeostasisGO:0060249110.020
regulation of purine nucleotide metabolic processGO:1900542370.020
endomembrane system organizationGO:0010256220.020
purine ribonucleoside triphosphate catabolic processGO:0009207720.020
cell morphogenesis involved in neuron differentiationGO:00486671110.020
response to organic substanceGO:00100331310.019
Mouse
male sex differentiationGO:0046661860.019
regulation of hydrolase activityGO:0051336450.019
intracellular transportGO:0046907770.019
Mouse
plasma membrane organizationGO:000700990.019
phagocytosis engulfmentGO:0006911980.019
ribonucleotide metabolic processGO:0009259990.019
protein oligomerizationGO:005125940.019
membrane invaginationGO:0010324980.018
regulation of vesicle mediated transportGO:0060627270.018
single organism membrane organizationGO:0044802350.018
digestive tract morphogenesisGO:0048546760.018
nitrogen compound transportGO:0071705490.018
ribose phosphate metabolic processGO:0019693990.018
cell recognitionGO:0008037850.018
response to heatGO:0009408500.017
purine nucleoside catabolic processGO:0006152750.017
single organism catabolic processGO:00447121290.017
system processGO:00030081360.017
Zebrafish Mouse Fly
engulfment of apoptotic cellGO:0043652940.017
tube developmentGO:00352951260.017
Mouse
sensory organ morphogenesisGO:009059620.017
nucleoside phosphate catabolic processGO:1901292770.017
cellular macromolecule biosynthetic processGO:00346452470.017
Mouse
response to bacteriumGO:0009617860.017
cellular amine metabolic processGO:0044106150.017
nucleic acid metabolic processGO:00903042990.017
Mouse
positive regulation of hydrolase activityGO:0051345380.017
amine metabolic processGO:0009308150.017
negative regulation of cellular component organizationGO:0051129330.017
nucleoside phosphate metabolic processGO:00067531080.017
homeostatic processGO:0042592510.016
Mouse
organophosphate catabolic processGO:0046434810.016
regulation of endocytosisGO:0030100250.016
purine nucleotide metabolic processGO:0006163950.016
oogenesisGO:00484772290.016
ovulationGO:0030728330.016
macromolecule modificationGO:00434122180.016
neuron projection morphogenesisGO:00488121140.016
mitotic nuclear divisionGO:0007067890.016
establishment of nucleus localizationGO:0040023550.016
regulation of macromolecule metabolic processGO:00602554210.016
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
regulation of nucleic acid templated transcriptionGO:19035061650.015
Mouse
multi organism reproductive behaviorGO:00447053870.015
secretion by cellGO:00329401380.015
glycosyl compound metabolic processGO:19016571000.015
ion homeostasisGO:0050801210.015
Mouse
neuron projection extensionGO:1990138370.015
cell adhesionGO:0007155210.015
cellular nitrogen compound biosynthetic processGO:00442711920.015
Mouse
transcription initiation from rna polymerase ii promoterGO:000636720.015
nucleoside metabolic processGO:0009116990.015
regulation of nucleotide catabolic processGO:0030811350.015
vulval developmentGO:00400253330.015
nucleus localizationGO:0051647550.014
striated muscle contractionGO:0006941170.014
Zebrafish Mouse
cellular nitrogen compound catabolic processGO:00442701190.014
nucleoside triphosphate metabolic processGO:0009141870.014
carboxylic acid metabolic processGO:0019752340.014
nucleotide catabolic processGO:0009166770.014
gene expressionGO:00104674120.014
Mouse
rna metabolic processGO:00160702280.014
Mouse
neuron differentiationGO:00301822170.014
purine nucleoside triphosphate metabolic processGO:0009144870.014
purine ribonucleoside metabolic processGO:0046128920.014
mesoderm developmentGO:0007498270.014
eating behaviorGO:0042755590.014
taxisGO:00423301280.014
spindle organizationGO:0007051920.014
organic cyclic compound catabolic processGO:19013611190.014
nucleobase containing compound catabolic processGO:00346551140.014
nucleoside catabolic processGO:0009164780.014
g protein coupled receptor signaling pathwayGO:0007186460.014
Mouse
cellular response to nitrogen compoundGO:1901699240.014
Mouse
negative regulation of multicellular organismal processGO:00512412360.014
negative regulation of developmental growthGO:0048640100.013
ribonucleoside triphosphate catabolic processGO:0009203720.013
regulation of cytoplasmic transportGO:190364930.013
Mouse
nervous system developmentGO:00073992530.013
meiotic cytokinesisGO:0033206150.013
regulation of atp catabolic processGO:190328930.013
regulation of response to woundingGO:190303410.013
microtubule based movementGO:0007018330.013
defense response to fungusGO:0050832190.013
regulation of cell cycleGO:00517261940.013
tissue morphogenesisGO:0048729650.013
Mouse
positive regulation of purine nucleotide catabolic processGO:0033123280.013
regulation of gene expressionGO:00104683660.013
Mouse
oxoacid metabolic processGO:0043436470.013
ion transmembrane transportGO:0034220910.013
Zebrafish Mouse
regulation of cellular catabolic processGO:0031329510.013
oocyte constructionGO:000730820.012
pole plasm assemblyGO:000731520.012
ribonucleoside catabolic processGO:0042454770.012
calcium ion transportGO:0006816160.012
Zebrafish Mouse
feeding behaviorGO:0007631700.012
sensory perception of smellGO:000760830.012
purine nucleoside monophosphate metabolic processGO:0009126430.012
phagocytosisGO:00069091150.012
cellular macromolecule localizationGO:0070727750.012
posttranscriptional gene silencing by rnaGO:00351941430.012
positive regulation of cysteine type endopeptidase activityGO:200105630.012
positive regulation of cellular metabolic processGO:00313251780.012
enzyme linked receptor protein signaling pathwayGO:0007167500.012
Mouse
single organism behaviorGO:0044708830.012
Zebrafish
multi multicellular organism processGO:00447063900.012
rna interferenceGO:00162461370.012
regulation of cell deathGO:0010941650.012
apical junction assemblyGO:004329710.012
positive regulation of catabolic processGO:0009896380.012
embryonic morphogenesisGO:00485981520.012
Mouse
regulation of ovipositionGO:0046662430.011
regulation of nucleotide metabolic processGO:0006140370.011
cognitionGO:0050890270.011
tissue developmentGO:00098881120.011
Mouse
regulation of cellular amino acid metabolic processGO:000652100.011
regulation of muscle contractionGO:0006937200.011
Mouse
carbohydrate derivative catabolic processGO:1901136820.011
peptidyl amino acid modificationGO:0018193580.011
phosphate containing compound metabolic processGO:00067962320.011
guanosine containing compound catabolic processGO:1901069480.011
tube morphogenesisGO:0035239790.011
Mouse
cytoskeleton dependent cytokinesisGO:0061640350.011
regulation of cellular amine metabolic processGO:003323800.011
endodermal cell differentiationGO:0035987180.011
regulation of apoptotic signaling pathwayGO:200123310.011
neuron projection developmentGO:00311751870.011
purine ribonucleoside catabolic processGO:0046130750.011
cell cell signalingGO:00072671180.011
Mouse
actin filament bundle organizationGO:006157230.010
organic acid metabolic processGO:0006082470.010
neuromuscular processGO:005090510.010
metal ion transportGO:0030001490.010
Zebrafish Mouse
regulation of nucleobase containing compound metabolic processGO:00192192220.010
Mouse
cuticle developmentGO:00423351000.010
sensory perceptionGO:0007600270.010
biological adhesionGO:0022610210.010
regulation of catalytic activityGO:0050790780.010
muscle contractionGO:0006936430.010
Zebrafish Mouse Fly

unc-68 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.079
cardiovascular system diseaseDOID:128700.079
muscle tissue diseaseDOID:6600.030
myopathyDOID:42300.030
heart diseaseDOID:11400.030
musculoskeletal system diseaseDOID:1700.030
cardiomyopathyDOID:005070000.030
muscular diseaseDOID:008000000.030
nervous system diseaseDOID:86300.010
disease of cellular proliferationDOID:1456600.010