Caenorhabditis elegans

101 known processes

dlk-1 (CELE_F33E2.2)

Protein DLK-1

dlk-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heterocycle biosynthetic processGO:00181301870.750
Human
cellular macromolecule biosynthetic processGO:00346452470.722
Human
negative regulation of biological processGO:00485195670.706
post embryonic developmentGO:000979121520.687
organic substance biosynthetic processGO:19015763230.655
Human
embryo development ending in birth or egg hatchingGO:000979229920.649
embryo developmentGO:000979030520.625
regulation of macromolecule metabolic processGO:00602554210.580
single organism reproductive processGO:004470211960.577
Fly
regulation of developmental processGO:00507936840.538
gene expressionGO:00104674120.522
Human
sex differentiationGO:00075489090.511
nucleic acid templated transcriptionGO:00976591690.502
Human
defense responseGO:00069522960.487
macromolecule biosynthetic processGO:00090592500.484
Human
organ developmentGO:004851311020.478
positive regulation of cellular biosynthetic processGO:00313281090.470
nucleobase containing compound biosynthetic processGO:00346541840.445
Human
negative regulation of cellular processGO:00485232390.435
regulation of gene expressionGO:00104683660.431
Human
establishment of localizationGO:005123411710.417
cellular response to organic substanceGO:00713101190.410
programmed cell deathGO:00125015000.407
positive regulation of transcription dna templatedGO:00458931020.391
cellular biosynthetic processGO:00442493150.390
Human
regulation of biosynthetic processGO:00098891890.390
Human
nucleic acid metabolic processGO:00903042990.381
Human
gonad developmentGO:00084068400.367
regulation of nucleobase containing compound metabolic processGO:00192192220.366
Human
cell cycle processGO:00224024820.365
organelle organizationGO:00069967830.358
Mouse Fly
regulation of multicellular organismal developmentGO:20000263170.356
cell deathGO:00082195470.349
multicellular organismal reproductive processGO:00486098150.349
Fly
positive regulation of macromolecule biosynthetic processGO:00105571090.338
multi organism reproductive processGO:00447038670.334
Fly
growthGO:00400075620.324
Fly
regulation of rna metabolic processGO:00512521730.305
Human
regulation of cellular metabolic processGO:00313233050.284
anatomical structure formation involved in morphogenesisGO:00486462500.281
positive regulation of nucleic acid templated transcriptionGO:19035081020.275
regulation of metabolic processGO:00192224780.273
vesicle mediated transportGO:00161928520.265
positive regulation of nitrogen compound metabolic processGO:00511731340.262
gamete generationGO:00072764610.260
Fly
genitalia developmentGO:00488067410.260
deathGO:00162655470.259
regulation of cellular macromolecule biosynthetic processGO:20001121880.259
Human
rna biosynthetic processGO:00327741690.256
Human
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.247
regulation of response to stimulusGO:00485832430.241
cellular localizationGO:00516413600.232
positive regulation of rna biosynthetic processGO:19026801020.227
regulation of transcription dna templatedGO:00063551640.225
Human
biosynthetic processGO:00090583230.222
Human
developmental growthGO:00485894120.217
Fly
regulation of nucleic acid templated transcriptionGO:19035061650.211
Human
macromolecular complex subunit organizationGO:00439333200.209
Mouse
cellular nitrogen compound biosynthetic processGO:00442711920.209
Human
head developmentGO:006032210.209
development of primary sexual characteristicsGO:00451378400.208
intracellular signal transductionGO:0035556960.206
cell developmentGO:00484686960.206
Fly
organic cyclic compound biosynthetic processGO:19013621950.204
Human
positive regulation of gene expressionGO:00106281120.202
enzyme linked receptor protein signaling pathwayGO:0007167500.198
positive regulation of nucleobase containing compound metabolic processGO:00459351340.194
reproductive system developmentGO:00614588500.192
multicellular organism reproductionGO:00325048190.192
Fly
positive regulation of multicellular organismal processGO:00512404170.186
developmental process involved in reproductionGO:000300611650.186
ovipositionGO:00189913640.185
response to organic substanceGO:00100331310.184
transportGO:000681010930.184
multi organism reproductive behaviorGO:00447053870.184
cell cycleGO:00070495260.183
protein metabolic processGO:00195384220.183
protein complex subunit organizationGO:00718222800.178
positive regulation of developmental growthGO:00486393540.176
locomotionGO:004001116340.174
receptor mediated endocytosisGO:00068987150.172
nucleobase containing compound metabolic processGO:00061394060.169
Human
reproductive structure developmentGO:00486088500.168
regulation of cellular component sizeGO:0032535400.165
aromatic compound biosynthetic processGO:00194381920.164
Human
regulation of multicellular organismal processGO:00512397260.163
cell projection morphogenesisGO:00488581480.159
Fly
positive regulation of multicellular organism growthGO:00400183520.158
cellular component assemblyGO:00226072930.154
regulation of rna biosynthetic processGO:20011411650.153
Human
regulation of transcription from rna polymerase ii promoterGO:00063571450.150
cell proliferationGO:00082831160.149
establishment of localization in cellGO:00516493180.146
multicellular organism growthGO:00352643850.145
apoptotic processGO:00069154780.145
endocytosisGO:00068978190.145
regulation of biological qualityGO:00650087410.145
cell morphogenesisGO:00009021630.143
Fly
multi organism behaviorGO:00517053890.142
regulation of growthGO:00400084090.139
positive regulation of epithelial cell proliferationGO:005067910.138
positive regulation of developmental processGO:00510944080.138
regulation of nitrogen compound metabolic processGO:00511712220.138
Human
positive regulation of rna metabolic processGO:00512541030.134
signal transductionGO:00071653170.134
positive regulation of metabolic processGO:00098931870.133
regulation of response to stressGO:0080134280.133
response to oxygen containing compoundGO:1901700440.132
neurogenesisGO:00220082360.128
Fly
negative regulation of metabolic processGO:00098922400.128
macromolecule modificationGO:00434122180.126
behaviorGO:00076105270.126
neurotransmitter secretionGO:0007269260.125
phosphorus metabolic processGO:00067932320.118
hermaphrodite genitalia developmentGO:00400357340.118
regulation of cellular biosynthetic processGO:00313261890.117
Human
innate immune responseGO:00450871900.117
cellular protein metabolic processGO:00442672790.116
regulation of primary metabolic processGO:00800902920.109
muscle tissue developmentGO:006053710.108
single organism behaviorGO:0044708830.107
tube developmentGO:00352951260.107
cellular response to stressGO:00335541620.107
Human Fly
cellular response to endogenous stimulusGO:0071495320.107
cellular component morphogenesisGO:00329893180.106
Fly
multi multicellular organism processGO:00447063900.105
reproductive behaviorGO:00190983870.105
single organism organelle organizationGO:19025895010.097
Mouse
digestive system developmentGO:00551231220.096
cellular component biogenesisGO:00440852970.096
mapk cascadeGO:0000165310.094
dauer larval developmentGO:0040024920.094
cell divisionGO:00513012620.092
regulation of macromolecule biosynthetic processGO:00105561890.092
Human
macromolecule localizationGO:00330367710.089
regulation of multicellular organism growthGO:00400143730.089
neuron developmentGO:00486661990.087
Fly
rna metabolic processGO:00160702280.087
Human
cell surface receptor signaling pathwayGO:00071661490.084
positive regulation of cellular metabolic processGO:00313251780.083
protein localizationGO:00081042050.083
dna metabolic processGO:0006259740.083
immune responseGO:00069551920.082
negative regulation of biosynthetic processGO:0009890650.080
positive regulation of growthGO:00459273690.077
regulation of organelle organizationGO:00330431640.076
response to endogenous stimulusGO:0009719330.076
cell morphogenesis involved in differentiationGO:00009041120.076
Fly
cell motilityGO:00488703130.075
negative regulation of response to stimulusGO:0048585730.075
organelle fissionGO:00482853630.075
positive regulation of biosynthetic processGO:00098911090.075
regulation of cell differentiationGO:0045595810.075
bmp signaling pathwayGO:003050930.074
negative regulation of macromolecule metabolic processGO:00106052290.074
macromolecular complex assemblyGO:00650031930.073
sexual reproductionGO:00199535460.073
Fly
multicellular organismal reproductive behaviorGO:00330573840.072
maintenance of locationGO:00512355800.071
cellular protein modification processGO:00064642070.071
regulation of cellular component organizationGO:00511282480.071
body morphogenesisGO:00101716200.070
phosphate containing compound metabolic processGO:00067962320.069
regulation of epithelial cell proliferationGO:005067810.069
nervous system developmentGO:00073992530.067
Fly
phosphorylationGO:00163101160.067
multicellular organismal agingGO:00102598120.067
cellular response to chemical stimulusGO:00708871290.066
epithelial cell proliferationGO:005067310.065
regulation of signal transductionGO:00099661350.065
determination of adult lifespanGO:00083408120.064
cellular process involved in reproduction in multicellular organismGO:00224123510.064
cytoskeleton organizationGO:00070103390.064
neuron projection morphogenesisGO:00488121140.064
Fly
protein modification processGO:00362112070.063
generation of neuronsGO:00486992350.063
Fly
post embryonic organ developmentGO:00485693360.062
signalingGO:00230524010.061
lipid localizationGO:00108765730.060
negative regulation of cell communicationGO:0010648610.060
single organism transportGO:00447654470.060
lipid storageGO:00199155650.059
regulation of meiotic cell cycleGO:00514451360.059
regulation of developmental growthGO:00486383890.059
transcription from rna polymerase ii promoterGO:00063661490.059
secretion by cellGO:00329401380.058
single organism signalingGO:00447004010.058
digestive tract developmentGO:00485651220.057
cellular component movementGO:00069283880.056
axon developmentGO:00615641630.055
Fly
negative regulation of gene expressionGO:00106292170.055
cell morphogenesis involved in neuron differentiationGO:00486671110.054
Fly
vulval developmentGO:00400253330.054
negative regulation of cellular metabolic processGO:0031324950.054
protein phosphorylationGO:0006468850.053
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178160.053
regulation of anatomical structure sizeGO:0090066460.053
cellular response to abiotic stimulusGO:007121440.053
tissue developmentGO:00098881120.052
regulation of cell sizeGO:0008361300.052
response to chemicalGO:00422213560.051
regulation of signalingGO:00230511720.050
positive regulation of cell projection organizationGO:003134640.049
negative regulation of cellular biosynthetic processGO:0031327650.048
regulation of cell proliferationGO:00421271050.048
positive regulation of neurogenesisGO:005076940.048
adult locomotory behaviorGO:000834410.048
cellular response to transforming growth factor beta stimulusGO:0071560130.047
positive regulation of macromolecule metabolic processGO:00106041490.046
neuron projection developmentGO:00311751870.046
Fly
regulation of phosphate metabolic processGO:0019220810.045
stem cell proliferationGO:007208990.045
cellular macromolecular complex assemblyGO:00346221840.044
positive regulation of cellular processGO:00485223320.043
single organism localizationGO:19025785180.043
negative regulation of signal transductionGO:0009968600.042
protein complex biogenesisGO:00702711860.042
pattern specification processGO:0007389590.041
regulation of anatomical structure morphogenesisGO:0022603510.041
synaptic growth at neuromuscular junctionGO:005112410.040
neurotransmitter transportGO:0006836320.040
small molecule metabolic processGO:00442811860.039
neuromuscular junction developmentGO:000752820.039
response to external stimulusGO:00096052890.038
spicule insertionGO:003460920.038
regulation of cell deathGO:0010941650.038
meiotic cell cycleGO:00513213350.038
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.037
mitotic cell cycle processGO:19030471940.037
negative regulation of nucleic acid templated transcriptionGO:1903507530.037
posttranscriptional regulation of gene expressionGO:00106081660.036
intraspecies interaction between organismsGO:005170330.036
regulation of cell communicationGO:00106461760.035
chromosome organizationGO:00512761040.035
Mouse
aromatic compound catabolic processGO:00194391160.035
germ cell developmentGO:00072813510.035
protein complex assemblyGO:00064611860.034
localization of cellGO:00516743130.034
epithelium developmentGO:0060429680.034
regulation of nematode larval developmentGO:00610622600.033
regulation of intracellular signal transductionGO:1902531770.033
nucleobase containing small molecule metabolic processGO:00550861150.032
negative regulation of rna metabolic processGO:0051253530.032
nucleoside phosphate metabolic processGO:00067531080.032
negative regulation of cellular protein metabolic processGO:0032269270.032
agingGO:00075688120.032
regulation of vulval developmentGO:00400282480.032
negative regulation of signalingGO:0023057610.031
organ morphogenesisGO:0009887670.031
system processGO:00030081360.031
sterol transportGO:001591840.031
regulation of mapk cascadeGO:0043408230.030
organic acid metabolic processGO:0006082470.030
regulation of nuclear divisionGO:00517831150.030
cell fate commitment involved in formation of primary germ layerGO:0060795330.029
homeostatic processGO:0042592510.028
negative regulation of vulval developmentGO:00400272060.027
axon guidanceGO:0007411820.027
cell fate commitmentGO:00451651390.027
transcription dna templatedGO:00063511680.027
Human
lipid metabolic processGO:0006629770.027
cell type specific apoptotic processGO:009728540.027
skeletal muscle organ developmentGO:006053830.026
synapse organizationGO:0050808240.026
synaptic transmissionGO:00072681060.026
negative regulation of nitrogen compound metabolic processGO:0051172630.026
negative regulation of nematode larval developmentGO:00610642080.026
regulation of cell cycle processGO:00105641450.025
negative regulation of transcription dna templatedGO:0045892530.025
molting cycleGO:00423032810.024
g protein coupled receptor signaling pathwayGO:0007186460.024
adult behaviorGO:003053430.024
cellular response to growth factor stimulusGO:0071363180.024
stress activated mapk cascadeGO:0051403100.024
Human
negative regulation of rna biosynthetic processGO:1902679530.023
regulation of nervous system developmentGO:0051960410.023
carbohydrate derivative metabolic processGO:19011351410.023
organic substance catabolic processGO:19015752940.022
actomyosin structure organizationGO:00310321540.022
regulation of neurotransmitter levelsGO:0001505360.022
stem cell differentiationGO:004886370.021
cell migrationGO:00164773060.021
regulation of post embryonic developmentGO:00485802600.021
positive regulation of proteasomal protein catabolic processGO:190180010.021
regulation of programmed cell deathGO:0043067500.021
single organism carbohydrate metabolic processGO:0044723290.021
tube morphogenesisGO:0035239790.020
stress activated protein kinase signaling cascadeGO:0031098100.020
Human
regulation of nucleocytoplasmic transportGO:004682230.020
organonitrogen compound metabolic processGO:19015641510.020
negative regulation of nucleobase containing compound metabolic processGO:0045934630.020
regulation of cell cycleGO:00517261940.020
nuclear migrationGO:0007097540.019
response to transforming growth factor betaGO:0071559130.019
regulation of phosphorus metabolic processGO:0051174810.019
regulation of bmp signaling pathwayGO:003051030.019
regulation of lipid metabolic processGO:001921640.019
regulation of cell developmentGO:0060284490.019
cellular macromolecule localizationGO:0070727750.019
positive regulation of neuron differentiationGO:004566640.019
regulation of catalytic activityGO:0050790780.019
organ growthGO:003526550.018
muscle structure developmentGO:00610611910.018
purine nucleotide metabolic processGO:0006163950.018
positive regulation of neuron projection developmentGO:001097640.018
taxisGO:00423301280.018
response to other organismGO:00517071010.018
cellular response to dna damage stimulusGO:0006974410.018
regulation of cellular protein metabolic processGO:0032268750.018
negative regulation of bmp signaling pathwayGO:003051410.018
meiotic nuclear divisionGO:00071263000.018
cellular catabolic processGO:00442481990.017
regulation of cell fate commitmentGO:0010453220.017
locomotory behaviorGO:0007626400.017
nucleotide metabolic processGO:00091171080.017
cell substrate adhesionGO:003158910.016
single organism biosynthetic processGO:0044711910.016
oxoacid metabolic processGO:0043436470.016
response to growth factorGO:0070848180.016
regulation of organ morphogenesisGO:200002740.016
sensory organ morphogenesisGO:009059620.016
positive regulation of catalytic activityGO:0043085590.016
carboxylic acid metabolic processGO:0019752340.015
regulation of cellular response to stressGO:0080135190.015
negative regulation of post embryonic developmentGO:00485812080.015
embryonic morphogenesisGO:00485981520.015
organophosphate metabolic processGO:00196371250.015
transforming growth factor beta receptor signaling pathwayGO:0007179130.015
regulation of meiosisGO:0040020940.015
response to fungusGO:0009620200.015
regulation of transportGO:0051049910.014
epithelial tube morphogenesisGO:006056210.014
regulation of neurotransmitter secretionGO:0046928160.014
response to abiotic stimulusGO:00096281520.014
cell cell signalingGO:00072671180.014
regulation of molecular functionGO:0065009890.014
carbohydrate derivative biosynthetic processGO:1901137460.014
oogenesisGO:00484772290.013
regulation of cellular amine metabolic processGO:003323800.013
canonical wnt signaling pathwayGO:006007030.013
positive regulation of cell adhesionGO:004578510.013
actin filament based processGO:00300291910.013
chemical homeostasisGO:0048878290.013
response to external biotic stimulusGO:00432071010.013
organelle localizationGO:00516401270.013
regulation of cellular catabolic processGO:0031329510.013
muscle system processGO:0003012430.013
regulation of cell divisionGO:00513021420.013
rho protein signal transductionGO:000726620.013
chromatin remodelingGO:000633820.012
posttranscriptional gene silencing by rnaGO:00351941430.012
molting cycle collagen and cuticulin based cuticleGO:00189962810.012
signal transduction by phosphorylationGO:0023014310.012
macromolecule catabolic processGO:00090572020.012
regulation of hydrolase activityGO:0051336450.012
regulation of apoptotic processGO:0042981360.012
positive regulation of cell differentiationGO:004559780.012
negative regulation of apoptotic processGO:0043066170.012
regulation of protein ubiquitinationGO:003139630.012
cellular protein complex assemblyGO:00436231780.012
regulation of protein metabolic processGO:0051246810.012
glycosyl compound metabolic processGO:19016571000.012
negative regulation of developmental processGO:00510932270.012
regulation of cellular ketone metabolic processGO:001056530.011
purine ribonucleotide metabolic processGO:0009150950.011
female gamete generationGO:00072922540.011
rna interferenceGO:00162461370.011
negative regulation of macromolecule biosynthetic processGO:0010558650.011
negative regulation of response to external stimulusGO:003210230.011
spermatogenesisGO:0007283410.011
Fly
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
long term memoryGO:000761620.011
regulation of localizationGO:00328791940.011
jnk cascadeGO:000725480.011
Human
cellular nitrogen compound catabolic processGO:00442701190.011
regulation of protein stabilityGO:003164730.011
striated muscle myosin thick filament assemblyGO:00716881380.011
response to woundingGO:000961140.011
Fly
gene silencing by rnaGO:00310471430.011
regulation of synapse assemblyGO:005196320.011
regulation of mitotic cell cycleGO:0007346760.011
regulation of catabolic processGO:0009894570.010
regulation of cell morphogenesisGO:0022604400.010
specification of axis polarityGO:0065001130.010
nematode male tail tip morphogenesisGO:0045138770.010
secretionGO:00469031470.010
mitotic nuclear divisionGO:0007067890.010
response to uv cGO:001022530.010
cellular amino acid metabolic processGO:0006520150.010

dlk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.042
cancerDOID:16200.042
disease of cellular proliferationDOID:1456600.042
gastrointestinal system cancerDOID:311900.042
disease of anatomical entityDOID:700.038
disease of metabolismDOID:001466700.019
large intestine cancerDOID:567200.017
intestinal cancerDOID:1015500.017