Caenorhabditis elegans

83 known processes

spk-1 (CELE_B0464.5)

Protein SPK-1

spk-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic cell cycleGO:00513213350.753
oocyte axis specificationGO:000730920.611
gamete generationGO:00072764610.596
establishment of localizationGO:005123411710.589
Yeast
oogenesisGO:00484772290.541
embryo developmentGO:000979030520.538
chromosome segregationGO:00070591800.499
Human
protein complex subunit organizationGO:00718222800.472
Fly
oocyte constructionGO:000730820.437
cell cycleGO:00070495260.396
embryo development ending in birth or egg hatchingGO:000979229920.389
sexual reproductionGO:00199535460.384
germ cell developmentGO:00072813510.373
cellular process involved in reproduction in multicellular organismGO:00224123510.328
cellular protein metabolic processGO:00442672790.325
regulation of molecular functionGO:0065009890.316
regulation of gene expressionGO:00104683660.310
Human Zebrafish Mouse
regulation of biosynthetic processGO:00098891890.291
multicellular organism reproductionGO:00325048190.286
immune responseGO:00069551920.279
multicellular organismal agingGO:00102598120.268
protein complex assemblyGO:00064611860.253
Fly
oocyte differentiationGO:0009994450.243
regulation of gene expression epigeneticGO:00400291630.235
gene silencingGO:00164581430.234
regulation of macromolecule metabolic processGO:00602554210.229
Human Zebrafish Mouse
vesicle mediated transportGO:00161928520.228
posttranscriptional gene silencingGO:00164411430.216
receptor mediated endocytosisGO:00068987150.215
cellular protein complex assemblyGO:00436231780.214
meiotic nuclear divisionGO:00071263000.209
Fly
regulation of cellular component organizationGO:00511282480.208
protein metabolic processGO:00195384220.201
cellular macromolecular complex assemblyGO:00346221840.196
Human Yeast Mouse
gene expressionGO:00104674120.195
Human Yeast Zebrafish Mouse
regulation of rna metabolic processGO:00512521730.191
Human Mouse
cellular catabolic processGO:00442481990.190
regulation of cellular macromolecule biosynthetic processGO:20001121880.186
macromolecule catabolic processGO:00090572020.173
meiotic cell cycle processGO:19030461700.165
Fly
regulation of cellular metabolic processGO:00313233050.163
Human Mouse
cell divisionGO:00513012620.162
mitotic nuclear divisionGO:0007067890.155
transportGO:000681010930.153
Yeast
single organism organelle organizationGO:19025895010.152
Fly
cellular localizationGO:00516413600.149
Yeast
pattern specification processGO:0007389590.146
Zebrafish
innate immune responseGO:00450871900.142
regulation of developmental growthGO:00486383890.140
organelle fissionGO:00482853630.137
Fly
maintenance of location in cellGO:0051651120.133
catabolic processGO:00090563180.132
female gamete generationGO:00072922540.132
molting cycleGO:00423032810.132
establishment of localization in cellGO:00516493180.130
Yeast
negative regulation of metabolic processGO:00098922400.127
body morphogenesisGO:00101716200.123
macromolecular complex subunit organizationGO:00439333200.121
Human Yeast Mouse Fly
positive regulation of multicellular organism growthGO:00400183520.120
oocyte developmentGO:0048599440.118
cell developmentGO:00484686960.117
protein catabolic processGO:00301631620.117
cellular component assemblyGO:00226072930.112
Human Yeast Mouse Fly
endocytosisGO:00068978190.109
macromolecule localizationGO:00330367710.109
Yeast
post embryonic developmentGO:000979121520.108
regulation of multicellular organismal processGO:00512397260.104
nucleoside triphosphate catabolic processGO:0009143720.098
single organism reproductive processGO:004470211960.096
rna biosynthetic processGO:00327741690.094
determination of adult lifespanGO:00083408120.093
agingGO:00075688120.091
protein complex biogenesisGO:00702711860.091
Fly
regulation of cellular catabolic processGO:0031329510.090
macromolecular complex assemblyGO:00650031930.088
Human Yeast Mouse Fly
centrosomal and pronuclear rotationGO:003504760.087
single organism localizationGO:19025785180.087
Yeast
organelle organizationGO:00069967830.085
Mouse Fly
positive regulation of macromolecule metabolic processGO:00106041490.083
Mouse
regulation of nuclear divisionGO:00517831150.083
regulation of protein catabolic processGO:0042176130.082
negative regulation of gene expressionGO:00106292170.082
cellular component biogenesisGO:00440852970.082
Human Yeast Mouse Fly
microtubule based processGO:00070171820.081
Fly
regulation of metabolic processGO:00192224780.081
Human Zebrafish Mouse
positive regulation of metabolic processGO:00098931870.080
Mouse
cell cycle processGO:00224024820.079
lipid localizationGO:00108765730.079
regulation of cellular component biogenesisGO:0044087260.078
production of sirna involved in rna interferenceGO:003042260.077
protein localizationGO:00081042050.077
Yeast
positive regulation of developmental growthGO:00486393540.075
lipid storageGO:00199155650.074
negative regulation of macromolecule metabolic processGO:00106052290.073
positive regulation of macromolecule biosynthetic processGO:00105571090.073
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243450.073
regulation of multicellular organism growthGO:00400143730.073
multicellular organism growthGO:00352643850.072
regulation of biological qualityGO:00650087410.072
Yeast Zebrafish
negative regulation of biological processGO:00485195670.071
ovipositionGO:00189913640.071
developmental process involved in reproductionGO:000300611650.071
regulation of protein metabolic processGO:0051246810.070
positive regulation of molecular functionGO:0044093610.069
maintenance of locationGO:00512355800.069
posttranscriptional regulation of gene expressionGO:00106081660.069
Zebrafish
purine nucleoside triphosphate catabolic processGO:0009146720.069
growthGO:00400075620.068
reproductive behaviorGO:00190983870.068
pole plasm assemblyGO:000731520.067
biosynthetic processGO:00090583230.067
translationGO:0006412370.065
maintenance of protein locationGO:0045185150.065
multi organism reproductive processGO:00447038670.064
ribonucleoprotein complex assemblyGO:002261840.063
Human Yeast Mouse
negative regulation of vulval developmentGO:00400272060.062
positive regulation of protein metabolic processGO:0051247450.061
genitalia developmentGO:00488067410.061
organic substance catabolic processGO:19015752940.061
gene silencing by rnaGO:00310471430.059
nucleoside catabolic processGO:0009164780.058
positive regulation of growthGO:00459273690.058
organonitrogen compound metabolic processGO:19015641510.057
posttranscriptional gene silencing by rnaGO:00351941430.057
aromatic compound catabolic processGO:00194391160.056
cellular component morphogenesisGO:00329893180.056
purine nucleoside monophosphate metabolic processGO:0009126430.055
neuromuscular junction developmentGO:000752820.054
actomyosin structure organizationGO:00310321540.054
positive regulation of catabolic processGO:0009896380.054
regulation of catabolic processGO:0009894570.053
molting cycle collagen and cuticulin based cuticleGO:00189962810.053
ribonucleotide catabolic processGO:0009261750.053
cellular protein localizationGO:0034613750.052
Yeast
regulation of meiotic cell cycleGO:00514451360.052
cellular macromolecule localizationGO:0070727750.052
Yeast
regulation of nucleic acid templated transcriptionGO:19035061650.051
purine ribonucleoside triphosphate metabolic processGO:0009205870.051
attachment of spindle microtubules to kinetochoreGO:000860880.050
intracellular transportGO:0046907770.050
Yeast
rna interferenceGO:00162461370.049
negative regulation of nucleic acid templated transcriptionGO:1903507530.049
macromolecule biosynthetic processGO:00090592500.048
multicellular organismal reproductive processGO:00486098150.047
actin filament based processGO:00300291910.047
mrna metabolic processGO:0016071310.047
Human Yeast Mouse
single organism intracellular transportGO:1902582700.046
Yeast
purine nucleoside catabolic processGO:0006152750.046
cytoskeleton organizationGO:00070103390.046
Fly
organophosphate metabolic processGO:00196371250.046
actin cytoskeleton organizationGO:00300361840.045
positive regulation of neurogenesisGO:005076940.045
regulation of growthGO:00400084090.044
synaptic growth at neuromuscular junctionGO:005112410.044
ribose phosphate metabolic processGO:0019693990.044
cellular component movementGO:00069283880.044
positive regulation of rna metabolic processGO:00512541030.043
regulation of primary metabolic processGO:00800902920.042
Human Mouse
regulation of cellular biosynthetic processGO:00313261890.041
multicellular organismal reproductive behaviorGO:00330573840.041
myofibril assemblyGO:00302391540.041
cellular protein catabolic processGO:0044257370.041
organ developmentGO:004851311020.041
regulation of cell cycleGO:00517261940.040
regulation of mitotic cell cycleGO:0007346760.040
regulation of multicellular organismal developmentGO:20000263170.040
cellular response to stressGO:00335541620.040
muscle tissue developmentGO:006053710.040
Mouse
transcription dna templatedGO:00063511680.039
modification dependent macromolecule catabolic processGO:0043632320.039
embryonic pattern specificationGO:0009880210.039
regulation of cellular protein metabolic processGO:0032268750.038
ribosome biogenesisGO:004225440.038
nucleobase containing compound metabolic processGO:00061394060.038
Human Yeast Mouse
cellular protein complex disassemblyGO:0043624180.038
regulation of phosphate metabolic processGO:0019220810.037
striated muscle myosin thick filament assemblyGO:00716881380.037
cell type specific apoptotic processGO:009728540.037
Mouse
positive regulation of jnk cascadeGO:004633030.037
defense responseGO:00069522960.036
regulation of organelle organizationGO:00330431640.036
positive regulation of multicellular organismal processGO:00512404170.036
collagen and cuticulin based cuticle developmentGO:0040002990.036
single organism transportGO:00447654470.036
Yeast
cytokinesisGO:0000910800.036
stress activated mapk cascadeGO:0051403100.036
regulation of cytoplasmic transportGO:190364930.035
Yeast
purine ribonucleotide catabolic processGO:0009154750.035
purine ribonucleoside triphosphate catabolic processGO:0009207720.035
myosin filament organizationGO:00310331380.035
cellular nitrogen compound catabolic processGO:00442701190.035
regulation of phosphorus metabolic processGO:0051174810.034
positive regulation of protein catabolic processGO:004573260.034
purine ribonucleoside catabolic processGO:0046130750.034
nucleobase containing compound catabolic processGO:00346551140.033
multi multicellular organism processGO:00447063900.033
purine nucleotide metabolic processGO:0006163950.033
negative regulation of developmental processGO:00510932270.032
intraspecies interaction between organismsGO:005170330.032
maintenance of protein location in cellGO:0032507120.032
ribonucleoside triphosphate metabolic processGO:0009199870.031
mrna processingGO:0006397130.031
Human Yeast Mouse
cellular macromolecule catabolic processGO:0044265730.031
negative regulation of signalingGO:0023057610.031
nucleotide catabolic processGO:0009166770.031
behaviorGO:00076105270.031
negative regulation of cellular processGO:00485232390.031
rna metabolic processGO:00160702280.031
Human Yeast Mouse
deathGO:00162655470.031
positive regulation of developmental processGO:00510944080.030
positive regulation of neuron differentiationGO:004566640.030
cuticle developmentGO:00423351000.030
positive regulation of cellular metabolic processGO:00313251780.030
response to abiotic stimulusGO:00096281520.030
reproductive system developmentGO:00614588500.030
nucleotide metabolic processGO:00091171080.029
vulval developmentGO:00400253330.029
ribonucleoside triphosphate catabolic processGO:0009203720.029
purine ribonucleotide metabolic processGO:0009150950.029
purine nucleotide catabolic processGO:0006195750.029
positive regulation of cellular processGO:00485223320.029
regulation of cell communicationGO:00106461760.029
nucleoside triphosphate metabolic processGO:0009141870.028
positive regulation of cellular catabolic processGO:0031331350.028
regulation of neurogenesisGO:0050767400.028
translational initiationGO:000641320.027
cell part morphogenesisGO:00329901520.027
negative regulation of post embryonic developmentGO:00485812080.027
golgi vesicle transportGO:004819330.027
regulation of macromolecule biosynthetic processGO:00105561890.027
protein targeting to mitochondrionGO:000662620.027
response to heatGO:0009408500.027
cellular macromolecule biosynthetic processGO:00346452470.027
male gamete generationGO:0048232410.027
taxisGO:00423301280.027
ribonucleotide metabolic processGO:0009259990.026
heterocycle biosynthetic processGO:00181301870.026
developmental growthGO:00485894120.026
purine nucleoside metabolic processGO:0042278920.026
regulation of nucleobase containing compound metabolic processGO:00192192220.026
Human Mouse
regulation of nematode larval developmentGO:00610622600.026
ribonucleoprotein complex subunit organizationGO:007182660.026
Human Yeast Mouse
regulation of jun kinase activityGO:004350630.026
cellular response to organic substanceGO:00713101190.026
purine nucleoside monophosphate catabolic processGO:0009128280.025
muscle structure developmentGO:00610611910.025
Mouse
spermatogenesisGO:0007283410.025
positive regulation of stress activated mapk cascadeGO:003287430.025
hermaphrodite genitalia developmentGO:00400357340.025
muscle cell developmentGO:00550011580.025
positive regulation of nucleic acid templated transcriptionGO:19035081020.025
regulation of mitosisGO:0007088180.025
regulation of transcription from rna polymerase ii promoterGO:00063571450.024
anatomical structure formation involved in morphogenesisGO:00486462500.024
Zebrafish Mouse
response to external biotic stimulusGO:00432071010.024
positive regulation of catalytic activityGO:0043085590.024
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.024
myosin filament assemblyGO:00310341380.024
regulation of cell developmentGO:0060284490.024
negative regulation of translationGO:0017148100.023
cellular response to abiotic stimulusGO:007121440.023
regulation of translationGO:0006417190.023
cellular response to dna damage stimulusGO:0006974410.023
heterocycle catabolic processGO:00467001190.023
positive regulation of biosynthetic processGO:00098911090.022
positive regulation of cellular protein catabolic processGO:190336430.022
endosomal transportGO:0016197260.022
organic cyclic compound catabolic processGO:19013611190.022
head developmentGO:006032210.022
chemotaxisGO:00069351200.022
developmental maturationGO:0021700260.022
microtubule anchoringGO:003445380.021
regulation of cytoskeleton organizationGO:0051493410.021
single organism catabolic processGO:00447121290.021
organophosphate catabolic processGO:0046434810.021
purine containing compound catabolic processGO:0072523750.021
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.021
apoptotic processGO:00069154780.020
mitotic sister chromatid segregationGO:0000070380.020
programmed cell deathGO:00125015000.020
negative regulation of cellular protein catabolic processGO:190336340.020
sensory organ morphogenesisGO:009059620.020
phagocytosisGO:00069091150.020
multi organism reproductive behaviorGO:00447053870.020
glycosyl compound metabolic processGO:19016571000.020
axon guidanceGO:0007411820.020
regulation of synapse assemblyGO:005196320.020
cellular amino acid metabolic processGO:0006520150.020
regulation of vulval developmentGO:00400282480.019
positive regulation of rna biosynthetic processGO:19026801020.019
protein transmembrane transportGO:007180640.019
regulation of localizationGO:00328791940.019
Yeast
pronuclear migrationGO:0035046510.019
gonad developmentGO:00084068400.019
striated muscle cell developmentGO:00550021570.019
establishment or maintenance of cell polarityGO:0007163630.019
regulation of rna biosynthetic processGO:20011411650.018
regulation of signalingGO:00230511720.018
nucleus localizationGO:0051647550.018
carbohydrate derivative catabolic processGO:1901136820.018
chromosome organizationGO:00512761040.018
Fly
meiotic chromosome segregationGO:00451321390.018
nucleic acid templated transcriptionGO:00976591690.018
development of primary sexual characteristicsGO:00451378400.018
cellular response to chemical stimulusGO:00708871290.018
regulation of nervous system developmentGO:0051960410.018
negative regulation of macromolecule biosynthetic processGO:0010558650.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305050.018
regulation of cell differentiationGO:0045595810.018
membrane invaginationGO:0010324980.017
organelle localizationGO:00516401270.017
dna templated transcription elongationGO:000635410.017
negative regulation of cellular component organizationGO:0051129330.017
establishment of protein localization to membraneGO:009015030.017
negative regulation of response to stimulusGO:0048585730.017
organic cyclic compound biosynthetic processGO:19013621950.017
negative regulation of gene expression epigeneticGO:004581420.017
response to other organismGO:00517071010.017
cellular component assembly involved in morphogenesisGO:00109271830.017
positive regulation of proteolysis involved in cellular protein catabolic processGO:190305210.017
post embryonic organ developmentGO:00485693360.017
nucleobase containing small molecule metabolic processGO:00550861150.017
negative regulation of proteolysis involved in cellular protein catabolic processGO:190305140.017
axis specificationGO:0009798230.017
macromolecule modificationGO:00434122180.017
regulation of neuron projection developmentGO:0010975310.017
transcription from rna polymerase ii promoterGO:00063661490.017
nuclear migrationGO:0007097540.017
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.016
negative regulation of nematode larval developmentGO:00610642080.016
negative regulation of multicellular organismal processGO:00512412360.016
ovulationGO:0030728330.016
cellular biosynthetic processGO:00442493150.016
positive regulation of cellular biosynthetic processGO:00313281090.016
nucleoside metabolic processGO:0009116990.016
inductive cell migrationGO:00400391450.016
response to osmotic stressGO:0006970290.016
locomotionGO:004001116340.016
organelle assemblyGO:00709252140.015
Fly
regulation of cell cycle processGO:00105641450.015
regulation of nitrogen compound metabolic processGO:00511712220.015
Human Mouse
regulation of cell divisionGO:00513021420.015
regulation of post embryonic developmentGO:00485802600.015
regulation of developmental processGO:00507936840.015
positive regulation of nucleobase containing compound metabolic processGO:00459351340.015
response to temperature stimulusGO:0009266660.015
regulation of catalytic activityGO:0050790780.015
cell maturationGO:0048469260.015
chromatin assembly or disassemblyGO:000633310.015
nucleoside phosphate metabolic processGO:00067531080.015
regulation of organ morphogenesisGO:200002740.015
cytoplasmic transportGO:0016482230.015
Yeast
segmentationGO:003528270.015
Zebrafish
positive regulation of proteasomal protein catabolic processGO:190180010.014
response to external stimulusGO:00096052890.014
nucleobase containing compound biosynthetic processGO:00346541840.014
nucleoside phosphate catabolic processGO:1901292770.014
regulation of transcription dna templatedGO:00063551640.014
regulation of nucleoside metabolic processGO:0009118370.014
positive regulation of purine nucleotide catabolic processGO:0033123280.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
neuron projection morphogenesisGO:00488121140.014
fertilizationGO:0009566630.014
proteolysis involved in cellular protein catabolic processGO:0051603320.014
regulation of meiosisGO:0040020940.014
purine ribonucleoside monophosphate catabolic processGO:0009169280.014
regulation of actin filament polymerizationGO:0030833110.013
cell recognitionGO:0008037850.013
cell morphogenesis involved in neuron differentiationGO:00486671110.013
regulation of cell morphogenesisGO:0022604400.013
transcription initiation from rna polymerase ii promoterGO:000636720.013
regulation of protein complex assemblyGO:0043254120.013
rna processingGO:0006396340.013
Human Yeast Mouse
establishment of cell polarityGO:0030010460.013
mitotic g2 m transition checkpointGO:004481810.013
female meiotic divisionGO:0007143170.013
Fly
striated muscle cell differentiationGO:00511461580.013
regulation of hydrolase activityGO:0051336450.013
negative regulation of cellular protein metabolic processGO:0032269270.013
negative regulation of cellular biosynthetic processGO:0031327650.013
protein phosphorylationGO:0006468850.013
establishment of organelle localizationGO:00516561230.012
atp catabolic processGO:0006200270.012
regulation of protein modification processGO:0031399460.012
muscle cell differentiationGO:00426921710.012
rna localizationGO:000640330.012
microtubule depolymerizationGO:0007019100.012
cell morphogenesis involved in differentiationGO:00009041120.012
mitotic cell cycle processGO:19030471940.012
developmental cell growthGO:0048588390.012
positive regulation of locomotionGO:0040017420.012
positive regulation of nucleoside metabolic processGO:0045979280.012
regulation of anatomical structure morphogenesisGO:0022603510.012
male sex differentiationGO:0046661860.012
membrane organizationGO:00610241350.012
positive regulation of transcription dna templatedGO:00458931020.012
response to biotic stimulusGO:00096071010.012
single organism cellular localizationGO:1902580720.012
Yeast
protein deubiquitinationGO:001657920.012
cellular response to topologically incorrect proteinGO:0035967760.012
multi organism behaviorGO:00517053890.011
organic substance biosynthetic processGO:19015763230.011
regulation of cellular amine metabolic processGO:003323800.011
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.011
establishment of spindle orientationGO:0051294340.011
cell deathGO:00082195470.011
generation of neuronsGO:00486992350.011
guanosine containing compound metabolic processGO:1901068490.011
regionalizationGO:0003002310.011
Zebrafish
positive regulation of gene expressionGO:00106281120.011
Mouse
negative regulation of organelle organizationGO:0010639200.011
single fertilizationGO:0007338610.011
phosphate containing compound metabolic processGO:00067962320.011
protein polymerizationGO:0051258260.011
regulation of transferase activityGO:0051338310.011
maternal determination of anterior posterior axis embryoGO:000835820.011
regenerationGO:003109940.010
cell cycle switching mitotic to meiotic cell cycleGO:0051728350.010
meiosis iGO:0007127190.010
actin filament based movementGO:003004840.010
regulation of fibroblast growth factor receptor signaling pathwayGO:004003620.010
small molecule metabolic processGO:00442811860.010
glycosyl compound catabolic processGO:1901658790.010
positive regulation of cellular component organizationGO:0051130340.010
regulation of chromatin modificationGO:190330820.010
guanosine containing compound catabolic processGO:1901069480.010

spk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.012