Caenorhabditis elegans

108 known processes

unc-52 (CELE_ZC101.2)

Protein UNC-52

unc-52 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
generation of neuronsGO:00486992350.904
cell projection organizationGO:00300302310.871
embryo developmentGO:000979030520.843
organ developmentGO:004851311020.839
cell developmentGO:00484686960.812
body morphogenesisGO:00101716200.763
embryo development ending in birth or egg hatchingGO:000979229920.750
sexual reproductionGO:00199535460.732
protein catabolic processGO:00301631620.719
post embryonic developmentGO:000979121520.717
muscle tissue developmentGO:006053710.673
Mouse
cell surface receptor signaling pathwayGO:00071661490.670
establishment of localizationGO:005123411710.647
organic substance catabolic processGO:19015752940.617
regulation of locomotionGO:00400121610.611
neuron projection developmentGO:00311751870.601
regulation of nucleic acid templated transcriptionGO:19035061650.581
neuron developmentGO:00486661990.576
neuron differentiationGO:00301822170.576
regulation of gene expressionGO:00104683660.568
multicellular organism reproductionGO:00325048190.562
positive regulation of multicellular organismal processGO:00512404170.557
rna biosynthetic processGO:00327741690.555
macromolecule catabolic processGO:00090572020.551
single organism reproductive processGO:004470211960.549
transcription dna templatedGO:00063511680.541
catabolic processGO:00090563180.528
cell motilityGO:00488703130.521
positive regulation of developmental processGO:00510944080.517
cellular nitrogen compound biosynthetic processGO:00442711920.510
axon developmentGO:00615641630.508
cell migrationGO:00164773060.502
neurogenesisGO:00220082360.499
gamete generationGO:00072764610.495
signal transductionGO:00071653170.482
regulation of cellular macromolecule biosynthetic processGO:20001121880.474
multicellular organismal reproductive processGO:00486098150.471
locomotionGO:004001116340.464
regulation of rna metabolic processGO:00512521730.462
gene expressionGO:00104674120.461
cell morphogenesisGO:00009021630.455
organ morphogenesisGO:0009887670.453
regulation of metabolic processGO:00192224780.451
regulation of rna biosynthetic processGO:20011411650.441
embryonic morphogenesisGO:00485981520.433
regulation of developmental processGO:00507936840.430
rna metabolic processGO:00160702280.430
cellular response to chemical stimulusGO:00708871290.404
positive regulation of locomotionGO:0040017420.403
developmental growthGO:00485894120.403
endocytosisGO:00068978190.403
receptor mediated endocytosisGO:00068987150.401
protein metabolic processGO:00195384220.394
female gamete generationGO:00072922540.391
developmental process involved in reproductionGO:000300611650.387
regulation of multicellular organismal processGO:00512397260.387
regulation of nitrogen compound metabolic processGO:00511712220.379
sex differentiationGO:00075489090.378
reproductive structure developmentGO:00486088500.376
tissue developmentGO:00098881120.369
Mouse
nucleic acid metabolic processGO:00903042990.368
tissue morphogenesisGO:0048729650.362
nucleic acid templated transcriptionGO:00976591690.353
heterocycle biosynthetic processGO:00181301870.350
regulation of transcription dna templatedGO:00063551640.340
nervous system developmentGO:00073992530.338
cell projection morphogenesisGO:00488581480.338
regulation of response to stimulusGO:00485832430.335
positive regulation of growthGO:00459273690.334
gonad developmentGO:00084068400.333
cell morphogenesis involved in differentiationGO:00009041120.328
organic cyclic compound biosynthetic processGO:19013621950.327
single organism signalingGO:00447004010.326
regulation of growthGO:00400084090.323
cellular component movementGO:00069283880.323
macromolecule biosynthetic processGO:00090592500.320
cellular component morphogenesisGO:00329893180.312
regulation of cellular component organizationGO:00511282480.311
hermaphrodite genitalia developmentGO:00400357340.310
regulation of macromolecule biosynthetic processGO:00105561890.303
signalingGO:00230524010.295
digestive tract morphogenesisGO:0048546760.293
regulation of nucleobase containing compound metabolic processGO:00192192220.281
agingGO:00075688120.278
regulation of biosynthetic processGO:00098891890.268
cellular macromolecule biosynthetic processGO:00346452470.268
organic substance biosynthetic processGO:19015763230.264
determination of adult lifespanGO:00083408120.261
regulation of signalingGO:00230511720.259
reproductive system developmentGO:00614588500.258
macromolecule localizationGO:00330367710.256
Mouse
multi organism reproductive processGO:00447038670.255
nucleobase containing compound biosynthetic processGO:00346541840.254
axonogenesisGO:00074091020.254
biosynthetic processGO:00090583230.248
organelle organizationGO:00069967830.247
multicellular organismal agingGO:00102598120.247
growthGO:00400075620.245
muscle system processGO:0003012430.244
regulation of primary metabolic processGO:00800902920.243
regulation of transcription from rna polymerase ii promoterGO:00063571450.243
single organism transportGO:00447654470.241
cellular process involved in reproduction in multicellular organismGO:00224123510.241
actin cytoskeleton organizationGO:00300361840.238
anatomical structure formation involved in morphogenesisGO:00486462500.236
localization of cellGO:00516743130.235
taxisGO:00423301280.228
cytoskeleton organizationGO:00070103390.227
nucleobase containing compound metabolic processGO:00061394060.224
phosphorus metabolic processGO:00067932320.224
response to chemicalGO:00422213560.221
protein phosphorylationGO:0006468850.219
apoptotic processGO:00069154780.217
positive regulation of cellular metabolic processGO:00313251780.216
intracellular signal transductionGO:0035556960.216
tube morphogenesisGO:0035239790.215
single organism localizationGO:19025785180.214
development of primary sexual characteristicsGO:00451378400.214
positive regulation of cellular processGO:00485223320.213
regulation of anatomical structure morphogenesisGO:0022603510.213
meiotic cell cycleGO:00513213350.211
cell part morphogenesisGO:00329901520.211
meiotic nuclear divisionGO:00071263000.211
cellular response to organic substanceGO:00713101190.209
vesicle mediated transportGO:00161928520.207
macromolecular complex subunit organizationGO:00439333200.206
neuron projection morphogenesisGO:00488121140.205
multicellular organism growthGO:00352643850.205
cellular biosynthetic processGO:00442493150.201
ovipositionGO:00189913640.200
aromatic compound biosynthetic processGO:00194381920.199
regulation of multicellular organismal developmentGO:20000263170.198
positive regulation of developmental growthGO:00486393540.196
regulation of biological qualityGO:00650087410.195
protein complex subunit organizationGO:00718222800.193
transportGO:000681010930.192
deathGO:00162655470.190
positive regulation of nitrogen compound metabolic processGO:00511731340.188
negative regulation of metabolic processGO:00098922400.185
cell growthGO:0016049440.185
neuron projection guidanceGO:0097485820.182
multi organism reproductive behaviorGO:00447053870.177
single organism organelle organizationGO:19025895010.171
cell morphogenesis involved in neuron differentiationGO:00486671110.171
behaviorGO:00076105270.169
cellular macromolecule localizationGO:0070727750.166
regulation of multicellular organism growthGO:00400143730.165
regulation of phosphorus metabolic processGO:0051174810.165
molting cycle collagen and cuticulin based cuticleGO:00189962810.164
cell cycleGO:00070495260.163
phosphate containing compound metabolic processGO:00067962320.159
positive regulation of metabolic processGO:00098931870.155
regulation of anatomical structure sizeGO:0090066460.155
single organism cellular localizationGO:1902580720.152
protein localizationGO:00081042050.146
Mouse
negative regulation of multicellular organismal processGO:00512412360.144
cellular component biogenesisGO:00440852970.144
secretionGO:00469031470.141
organelle assemblyGO:00709252140.141
response to topologically incorrect proteinGO:0035966820.138
defense responseGO:00069522960.132
cellular component assemblyGO:00226072930.132
multicellular organismal reproductive behaviorGO:00330573840.131
inductive cell migrationGO:00400391450.131
negative regulation of macromolecule metabolic processGO:00106052290.130
regulation of phosphate metabolic processGO:0019220810.129
genitalia developmentGO:00488067410.129
regulation of cellular metabolic processGO:00313233050.129
head developmentGO:006032210.128
Mouse
cellular localizationGO:00516413600.128
positive regulation of macromolecule metabolic processGO:00106041490.127
negative regulation of biological processGO:00485195670.127
muscle cell differentiationGO:00426921710.125
regulation of developmental growthGO:00486383890.124
muscle organ developmentGO:0007517260.123
regulation of cell motilityGO:2000145570.121
regulation of signal transductionGO:00099661350.117
chemotaxisGO:00069351200.117
regulation of cell communicationGO:00106461760.116
er nucleus signaling pathwayGO:0006984660.111
enzyme linked receptor protein signaling pathwayGO:0007167500.110
germ cell developmentGO:00072813510.109
embryonic body morphogenesisGO:0010172490.109
homeostatic processGO:0042592510.108
regulation of nematode larval developmentGO:00610622600.107
actin filament organizationGO:0007015210.107
regulation of localizationGO:00328791940.106
negative regulation of cellular metabolic processGO:0031324950.105
cellular protein localizationGO:0034613750.104
negative regulation of developmental processGO:00510932270.104
regulation of catabolic processGO:0009894570.104
molting cycleGO:00423032810.104
cellular catabolic processGO:00442481990.103
organelle fissionGO:00482853630.103
cell fate commitmentGO:00451651390.102
muscle cell developmentGO:00550011580.101
negative regulation of biosynthetic processGO:0009890650.100
membrane organizationGO:00610241350.099
digestive tract developmentGO:00485651220.099
regulation of cell migrationGO:0030334550.097
positive regulation of biosynthetic processGO:00098911090.096
system processGO:00030081360.096
cellular protein metabolic processGO:00442672790.095
protein complex assemblyGO:00064611860.095
regulation of cell differentiationGO:0045595810.095
regulation of macromolecule metabolic processGO:00602554210.095
lipid localizationGO:00108765730.094
cell deathGO:00082195470.094
positive regulation of multicellular organism growthGO:00400183520.091
regulation of intracellular signal transductionGO:1902531770.091
regulation of cellular biosynthetic processGO:00313261890.090
protein complex biogenesisGO:00702711860.089
oogenesisGO:00484772290.089
tube developmentGO:00352951260.088
response to endoplasmic reticulum stressGO:0034976710.086
maintenance of locationGO:00512355800.084
positive regulation of phosphorus metabolic processGO:0010562560.083
programmed cell deathGO:00125015000.083
cell proliferationGO:00082831160.082
feeding behaviorGO:0007631700.082
response to external stimulusGO:00096052890.080
organonitrogen compound metabolic processGO:19015641510.079
multi multicellular organism processGO:00447063900.077
striated muscle cell developmentGO:00550021570.077
macromolecule modificationGO:00434122180.076
developmental cell growthGO:0048588390.075
establishment of localization in cellGO:00516493180.075
sensory organ morphogenesisGO:009059620.074
regulation of cell deathGO:0010941650.073
lipid storageGO:00199155650.073
reproductive behaviorGO:00190983870.072
response to unfolded proteinGO:0006986710.071
axon guidanceGO:0007411820.071
carbohydrate derivative metabolic processGO:19011351410.070
regulation of post embryonic developmentGO:00485802600.070
cell projection assemblyGO:0030031350.070
regulation of apoptotic processGO:0042981360.069
cellular response to topologically incorrect proteinGO:0035967760.069
positive regulation of cell migrationGO:003033530.069
nematode male tail tip morphogenesisGO:0045138770.069
positive regulation of nucleobase containing compound metabolic processGO:00459351340.068
mesoderm developmentGO:0007498270.068
negative regulation of nitrogen compound metabolic processGO:0051172630.066
cellular protein complex assemblyGO:00436231780.066
regulation of catalytic activityGO:0050790780.065
pattern specification processGO:0007389590.065
muscle structure developmentGO:00610611910.065
muscle organ morphogenesisGO:004864440.064
epithelium developmentGO:0060429680.063
negative regulation of gene expressionGO:00106292170.063
post embryonic organ developmentGO:00485693360.062
positive regulation of cellular biosynthetic processGO:00313281090.062
cell cycle processGO:00224024820.062
secretion by cellGO:00329401380.061
digestive system developmentGO:00551231220.061
positive regulation of gene expressionGO:00106281120.060
pharyngeal pumpingGO:0043050580.060
negative regulation of response to stimulusGO:0048585730.059
transcription from rna polymerase ii promoterGO:00063661490.059
positive regulation of cell communicationGO:0010647690.057
cellular component assembly involved in morphogenesisGO:00109271830.057
cation homeostasisGO:0055080200.056
actin filament based processGO:00300291910.055
skeletal muscle organ developmentGO:006053830.055
small molecule metabolic processGO:00442811860.054
positive regulation of macromolecule biosynthetic processGO:00105571090.054
positive regulation of rna metabolic processGO:00512541030.054
negative regulation of nucleobase containing compound metabolic processGO:0045934630.053
eating behaviorGO:0042755590.053
peptidyl amino acid modificationGO:0018193580.052
epithelial tube morphogenesisGO:006056210.052
vulval developmentGO:00400253330.051
regulation of cell cycleGO:00517261940.051
single organism catabolic processGO:00447121290.051
organophosphate metabolic processGO:00196371250.050
striated muscle cell differentiationGO:00511461580.049
phosphorylationGO:00163101160.048
regulation of protein metabolic processGO:0051246810.048
regulation of programmed cell deathGO:0043067500.047
endoplasmic reticulum unfolded protein responseGO:0030968660.047
striated muscle myosin thick filament assemblyGO:00716881380.047
sarcomere organizationGO:0045214100.046
cell divisionGO:00513012620.046
multi organism behaviorGO:00517053890.046
macromolecular complex assemblyGO:00650031930.045
calcium mediated signalingGO:001972230.045
actomyosin structure organizationGO:00310321540.043
negative regulation of cellular biosynthetic processGO:0031327650.042
organophosphate catabolic processGO:0046434810.042
negative regulation of nematode larval developmentGO:00610642080.042
cellular macromolecular complex assemblyGO:00346221840.042
regulation of cellular component movementGO:0051270620.041
cellular protein modification processGO:00064642070.040
male sex differentiationGO:0046661860.040
cell cell signalingGO:00072671180.039
negative regulation of signal transductionGO:0009968600.039
regulation of vulval developmentGO:00400282480.039
organic substance transportGO:00717021130.038
regulation of cell morphogenesisGO:0022604400.038
regulation of atp catabolic processGO:190328930.038
protein transportGO:0015031450.038
regulation of organelle organizationGO:00330431640.037
regulation of phosphorylationGO:0042325450.037
apoptotic cell clearanceGO:00432771110.036
regulation of cellular component sizeGO:0032535400.036
regulation of protein localizationGO:0032880500.035
epithelial cell proliferationGO:005067310.035
neuron recognitionGO:0008038830.035
response to organic substanceGO:00100331310.035
myofibril assemblyGO:00302391540.034
negative regulation of cellular processGO:00485232390.034
cell recognitionGO:0008037850.034
chromosome segregationGO:00070591800.034
myosin filament organizationGO:00310331380.033
phagocytosis engulfmentGO:0006911980.033
cellular response to stressGO:00335541620.033
membrane invaginationGO:0010324980.032
regulation of apoptotic signaling pathwayGO:200123310.032
regulation of cell proliferationGO:00421271050.031
regulation of cellular ketone metabolic processGO:001056530.031
gastrulationGO:0007369580.031
engulfment of apoptotic cellGO:0043652940.031
protein modification processGO:00362112070.031
cuticle developmentGO:00423351000.031
positive regulation of phosphate metabolic processGO:0045937560.030
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.030
single organism membrane organizationGO:0044802350.030
positive regulation of signal transductionGO:0009967400.030
regulation of system processGO:0044057270.030
positive regulation of nucleic acid templated transcriptionGO:19035081020.030
nucleoside triphosphate catabolic processGO:0009143720.030
cellular response to unfolded proteinGO:0034620710.029
multicellular organismal movementGO:005087920.029
response to woundingGO:000961140.029
regulation of cellular localizationGO:0060341420.028
regulation of cellular catabolic processGO:0031329510.028
cellular response to growth factor stimulusGO:0071363180.028
positive regulation of phosphorylationGO:0042327270.027
establishment of protein localizationGO:0045184500.027
ion homeostasisGO:0050801210.027
positive regulation of signalingGO:0023056660.027
ovulationGO:0030728330.027
negative regulation of signalingGO:0023057610.026
excretionGO:0007588490.026
response to growth factorGO:0070848180.026
muscle contractionGO:0006936430.025
single organism intracellular transportGO:1902582700.025
meiotic cell cycle processGO:19030461700.025
phagocytosisGO:00069091150.025
negative regulation of vulval developmentGO:00400272060.025
microtubule based processGO:00070171820.024
axonal fasciculationGO:0007413790.024
striated muscle contractionGO:0006941170.024
mitotic cell cycle processGO:19030471940.024
negative regulation of cell communicationGO:0010648610.024
negative regulation of post embryonic developmentGO:00485812080.024
regulation of cellular component biogenesisGO:0044087260.023
carboxylic acid metabolic processGO:0019752340.023
response to abiotic stimulusGO:00096281520.023
negative regulation of programmed cell deathGO:0043069190.023
purine containing compound catabolic processGO:0072523750.022
regulation of cell developmentGO:0060284490.022
nucleoside phosphate catabolic processGO:1901292770.022
oxoacid metabolic processGO:0043436470.022
skeletal muscle thin filament assemblyGO:003024030.022
regulation of cellular amine metabolic processGO:003323800.022
cellular ketone metabolic processGO:0042180140.021
positive regulation of nucleotide catabolic processGO:0030813280.021
negative regulation of cellular catabolic processGO:003133090.021
regulation of behaviorGO:0050795970.021
response to other organismGO:00517071010.021
negative regulation of apoptotic processGO:0043066170.021
ribonucleoside metabolic processGO:0009119980.021
intracellular transportGO:0046907770.021
positive regulation of rna biosynthetic processGO:19026801020.020
purine nucleoside catabolic processGO:0006152750.020
cellular amino acid metabolic processGO:0006520150.020
purine containing compound metabolic processGO:0072521950.020
cell substrate adhesionGO:003158910.020
protein localization to organelleGO:0033365370.020
male anatomical structure morphogenesisGO:0090598780.020
nucleobase containing small molecule metabolic processGO:00550861150.020
bmp signaling pathwayGO:003050930.020
single organism biosynthetic processGO:0044711910.020
collagen and cuticulin based cuticle developmentGO:0040002990.020
positive regulation of molecular functionGO:0044093610.020
regulation of nucleotide catabolic processGO:0030811350.020
negative regulation of nucleic acid templated transcriptionGO:1903507530.019
neurological system processGO:0050877530.019
protein targetingGO:0006605100.019
chemical homeostasisGO:0048878290.019
regulation of molecular functionGO:0065009890.019
establishment or maintenance of cell polarityGO:0007163630.019
regulation of cellular protein metabolic processGO:0032268750.018
amine metabolic processGO:0009308150.018
myosin filament assemblyGO:00310341380.018
positive regulation of catalytic activityGO:0043085590.018
nucleoside metabolic processGO:0009116990.018
response to inorganic substanceGO:0010035500.018
response to external biotic stimulusGO:00432071010.017
organic acid metabolic processGO:0006082470.017
posttranscriptional regulation of gene expressionGO:00106081660.017
nucleotide catabolic processGO:0009166770.017
positive regulation of cysteine type endopeptidase activityGO:200105630.017
cellular amine metabolic processGO:0044106150.017
regulation of vesicle mediated transportGO:0060627270.016
cytoplasmic transportGO:0016482230.016
organic cyclic compound catabolic processGO:19013611190.016
purine nucleotide catabolic processGO:0006195750.016
actin filament bundle assemblyGO:005101730.016
developmental growth involved in morphogenesisGO:0060560370.016
purine nucleoside metabolic processGO:0042278920.016
regulation of actin filament based processGO:0032970220.016
negative regulation of rna metabolic processGO:0051253530.016
regulation of gene expression epigeneticGO:00400291630.015
nucleobase containing compound catabolic processGO:00346551140.015
negative regulation of rna biosynthetic processGO:1902679530.015
regulation of cellular amino acid metabolic processGO:000652100.015
cellular nitrogen compound catabolic processGO:00442701190.014
maintenance of location in cellGO:0051651120.014
glycosyl compound catabolic processGO:1901658790.014
regulation of protein modification processGO:0031399460.014
transmembrane transportGO:00550851100.014
ribose phosphate metabolic processGO:0019693990.013
positive regulation of transcription dna templatedGO:00458931020.013
single organism behaviorGO:0044708830.013
positive regulation of cellular component organizationGO:0051130340.013
regulation of purine nucleotide catabolic processGO:0033121350.013
skin developmentGO:0043588240.013
ion transportGO:00068111130.013
negative regulation of cell deathGO:0060548210.013
establishment of protein localization to membraneGO:009015030.013
defecationGO:0030421470.013
carbohydrate derivative catabolic processGO:1901136820.013
negative regulation of catalytic activityGO:0043086150.013
cytokinesisGO:0000910800.012
inorganic cation transmembrane transportGO:0098662460.012
regulation of nucleoside metabolic processGO:0009118370.012
determination of bilateral symmetryGO:000985590.012
purine ribonucleotide metabolic processGO:0009150950.012
anatomical structure homeostasisGO:0060249110.012
regulation of transportGO:0051049910.012
cellular response to endogenous stimulusGO:0071495320.012
regulation of protein kinase activityGO:0045859280.012
negative regulation of transcription dna templatedGO:0045892530.011
cell adhesionGO:0007155210.011
aromatic compound catabolic processGO:00194391160.011
regulation of transferase activityGO:0051338310.011
mitochondrion organizationGO:0007005200.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178160.011
establishment of organelle localizationGO:00516561230.011
purine nucleoside triphosphate metabolic processGO:0009144870.011
response to oxygen containing compoundGO:1901700440.011
cation transportGO:0006812780.011
regulation of cell cycle processGO:00105641450.011
positive regulation of protein transportGO:005122240.011
regulation of hydrolase activityGO:0051336450.011
establishment of protein localization to organelleGO:007259490.011
positive regulation of response to stimulusGO:0048584550.010
response to bacteriumGO:0009617860.010
positive regulation of cellular catabolic processGO:0031331350.010
stem cell differentiationGO:004886370.010
positive regulation of purine nucleotide catabolic processGO:0033123280.010
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.010
protein localization to nucleusGO:0034504110.010
regulation of kinase activityGO:0043549290.010

unc-52 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.109
musculoskeletal system diseaseDOID:1700.075
muscular diseaseDOID:008000000.042
myopathyDOID:42300.042
muscle tissue diseaseDOID:6600.042
nervous system diseaseDOID:86300.020
cardiovascular system diseaseDOID:128700.018
cardiomyopathyDOID:005070000.018
heart diseaseDOID:11400.018
dilated cardiomyopathyDOID:1293000.011
intrinsic cardiomyopathyDOID:006003600.011