Caenorhabditis elegans

45 known processes

age-1 (CELE_B0334.8)

Protein AGE-1

age-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.740
multicellular organism reproductionGO:00325048190.712
Fly
embryo development ending in birth or egg hatchingGO:000979229920.689
post embryonic developmentGO:000979121520.679
locomotionGO:004001116340.572
establishment of localizationGO:005123411710.569
Worm
single organism organelle organizationGO:19025895010.559
regulation of macromolecule metabolic processGO:00602554210.495
Mouse Fly
neurogenesisGO:00220082360.387
Zebrafish Fly
regulation of cellular macromolecule biosynthetic processGO:20001121880.382
Fly
cell projection organizationGO:00300302310.348
Zebrafish Fly
single organism reproductive processGO:004470211960.333
Fly
vesicle mediated transportGO:00161928520.332
Worm
nervous system developmentGO:00073992530.329
Zebrafish Fly
endocytosisGO:00068978190.281
Worm
cell developmentGO:00484686960.277
Zebrafish Fly
positive regulation of biosynthetic processGO:00098911090.267
Fly
negative regulation of biological processGO:00485195670.264
Human Mouse Fly
multi organism reproductive processGO:00447038670.262
Fly
apoptotic processGO:00069154780.260
Human Mouse
nucleic acid metabolic processGO:00903042990.244
Mouse
negative regulation of macromolecule metabolic processGO:00106052290.238
negative regulation of metabolic processGO:00098922400.235
Fly
multicellular organismal reproductive processGO:00486098150.233
Fly
deathGO:00162655470.224
Human Mouse
signalingGO:00230524010.221
Mouse Fly
signal transductionGO:00071653170.212
Mouse Fly
regulation of primary metabolic processGO:00800902920.211
Mouse Fly
regulation of gene expression epigeneticGO:00400291630.197
Mouse
organelle organizationGO:00069967830.195
Worm
gamete generationGO:00072764610.190
Fly
cellular process involved in reproduction in multicellular organismGO:00224123510.190
Fly
female gamete generationGO:00072922540.184
Fly
transportGO:000681010930.181
Worm
protein modification processGO:00362112070.179
Mouse
organic substance biosynthetic processGO:19015763230.163
Human Mouse Worm Fly
multicellular organismal agingGO:00102598120.160
regulation of cellular metabolic processGO:00313233050.157
Mouse Fly
neuron projection developmentGO:00311751870.152
Zebrafish Fly
negative regulation of developmental processGO:00510932270.150
heterocycle biosynthetic processGO:00181301870.143
cellular macromolecule biosynthetic processGO:00346452470.140
Fly
cell deathGO:00082195470.139
Human Mouse
regulation of gene expressionGO:00104683660.136
Mouse Fly
single organism transportGO:00447654470.134
Worm
cellular protein modification processGO:00064642070.133
Mouse
sex differentiationGO:00075489090.133
negative regulation of nematode larval developmentGO:00610642080.132
biosynthetic processGO:00090583230.131
Human Mouse Worm Fly
regulation of cellular biosynthetic processGO:00313261890.130
Fly
negative regulation of gene expressionGO:00106292170.129
negative regulation of vulval developmentGO:00400272060.125
cell cycleGO:00070495260.123
Fly
multicellular organismal reproductive behaviorGO:00330573840.121
developmental process involved in reproductionGO:000300611650.120
Fly
neuron developmentGO:00486661990.118
Zebrafish Fly
chromosome organizationGO:00512761040.110
taxisGO:00423301280.108
regulation of metabolic processGO:00192224780.104
Mouse Fly
cell cycle processGO:00224024820.104
neuron projection morphogenesisGO:00488121140.103
Zebrafish Fly
determination of adult lifespanGO:00083408120.103
establishment of cell polarityGO:0030010460.102
single organism localizationGO:19025785180.102
Worm
germ cell developmentGO:00072813510.102
Fly
cell morphogenesis involved in neuron differentiationGO:00486671110.102
Zebrafish Fly
nucleobase containing compound biosynthetic processGO:00346541840.101
response to organic substanceGO:00100331310.101
posttranscriptional regulation of gene expressionGO:00106081660.101
Fly
regulation of multicellular organismal developmentGO:20000263170.099
Zebrafish Fly
posttranscriptional gene silencing by rnaGO:00351941430.099
organ developmentGO:004851311020.098
Fly
body morphogenesisGO:00101716200.097
cellular component assemblyGO:00226072930.097
Fly
ovipositionGO:00189913640.096
macromolecule biosynthetic processGO:00090592500.096
Fly
multicellular organism growthGO:00352643850.093
Mouse Fly
regulation of macromolecule biosynthetic processGO:00105561890.093
Fly
macromolecule localizationGO:00330367710.090
Worm
gene expressionGO:00104674120.090
Fly
protein localizationGO:00081042050.090
cellular nitrogen compound biosynthetic processGO:00442711920.089
cellular protein metabolic processGO:00442672790.089
Mouse Fly
aromatic compound biosynthetic processGO:00194381920.086
cell part morphogenesisGO:00329901520.085
Zebrafish Fly
regulation of developmental processGO:00507936840.085
Zebrafish Mouse Fly
sexual reproductionGO:00199535460.084
Fly
regulation of nitrogen compound metabolic processGO:00511712220.083
Mouse
regulation of nematode larval developmentGO:00610622600.083
development of primary sexual characteristicsGO:00451378400.081
oogenesisGO:00484772290.081
Fly
posttranscriptional gene silencingGO:00164411430.081
genitalia developmentGO:00488067410.080
positive regulation of rna biosynthetic processGO:19026801020.080
agingGO:00075688120.078
reproductive structure developmentGO:00486088500.077
neuron differentiationGO:00301822170.076
Zebrafish Fly
positive regulation of cellular biosynthetic processGO:00313281090.075
Fly
multi organism behaviorGO:00517053890.071
protein metabolic processGO:00195384220.070
Mouse Fly
phosphorus metabolic processGO:00067932320.069
Human Mouse Worm Fly
immune responseGO:00069551920.069
nucleic acid templated transcriptionGO:00976591690.067
rna metabolic processGO:00160702280.067
cellular localizationGO:00516413600.066
multi organism reproductive behaviorGO:00447053870.065
regulation of multicellular organismal processGO:00512397260.065
Zebrafish Mouse Fly
positive regulation of response to stimulusGO:0048584550.065
developmental maturationGO:0021700260.063
Fly
regulation of biological qualityGO:00650087410.061
Zebrafish Mouse Worm Fly
cellular component morphogenesisGO:00329893180.060
Zebrafish Fly
regulation of biosynthetic processGO:00098891890.060
Fly
regulation of response to stimulusGO:00485832430.060
vulval developmentGO:00400253330.060
regulation of cell deathGO:0010941650.060
Human Mouse
regulation of cell communicationGO:00106461760.060
Fly
reproductive behaviorGO:00190983870.057
lipid storageGO:00199155650.057
Worm
regulation of vulval developmentGO:00400282480.057
cellular biosynthetic processGO:00442493150.054
Human Mouse Worm Fly
maintenance of locationGO:00512355800.054
Worm
receptor mediated endocytosisGO:00068987150.053
rna interferenceGO:00162461370.053
neuron recognitionGO:0008038830.052
rna biosynthetic processGO:00327741690.051
negative regulation of post embryonic developmentGO:00485812080.051
small molecule metabolic processGO:00442811860.051
regulation of transcription dna templatedGO:00063551640.050
nucleobase containing compound metabolic processGO:00061394060.050
Mouse
lipid localizationGO:00108765730.050
Worm
gene silencing by rnaGO:00310471430.048
gene silencingGO:00164581430.048
regulation of rna biosynthetic processGO:20011411650.048
striated muscle cell differentiationGO:00511461580.048
organic cyclic compound biosynthetic processGO:19013621950.047
axonogenesisGO:00074091020.047
Zebrafish
organonitrogen compound metabolic processGO:19015641510.047
response to chemicalGO:00422213560.047
cell divisionGO:00513012620.047
Mouse
cell morphogenesisGO:00009021630.046
Zebrafish Fly
cellular response to organic substanceGO:00713101190.046
regulation of signal transductionGO:00099661350.045
Fly
behaviorGO:00076105270.045
cell surface receptor signaling pathwayGO:00071661490.045
Mouse Fly
positive regulation of macromolecule biosynthetic processGO:00105571090.045
Fly
macromolecule modificationGO:00434122180.045
Mouse
membrane organizationGO:00610241350.044
Worm
positive regulation of multicellular organismal processGO:00512404170.043
Fly
axon developmentGO:00615641630.043
Zebrafish
cytoskeleton organizationGO:00070103390.043
response to external stimulusGO:00096052890.043
growthGO:00400075620.042
Zebrafish Mouse Fly
lipid metabolic processGO:0006629770.042
Human Mouse Worm Fly
developmental growthGO:00485894120.042
Zebrafish Mouse Fly
cellular response to nitrogen compoundGO:1901699240.041
response to abiotic stimulusGO:00096281520.040
Worm
negative regulation of cellular processGO:00485232390.040
Human Mouse Fly
tissue developmentGO:00098881120.040
establishment or maintenance of cell polarityGO:0007163630.040
ribose phosphate metabolic processGO:0019693990.038
dendrite developmentGO:0016358420.038
Fly
cellular component biogenesisGO:00440852970.038
Fly
negative regulation of cellular metabolic processGO:0031324950.037
Fly
programmed cell deathGO:00125015000.037
Human Mouse
catabolic processGO:00090563180.037
Fly
multi multicellular organism processGO:00447063900.037
positive regulation of growthGO:00459273690.037
Fly
generation of neuronsGO:00486992350.036
Zebrafish Fly
hermaphrodite genitalia developmentGO:00400357340.035
regulation of nucleobase containing compound metabolic processGO:00192192220.035
Mouse
regulation of post embryonic developmentGO:00485802600.035
regulation of rna metabolic processGO:00512521730.035
regulation of growthGO:00400084090.034
Zebrafish Mouse Fly
muscle tissue developmentGO:006053710.033
head developmentGO:006032210.033
establishment of organelle localizationGO:00516561230.033
regulation of developmental growthGO:00486383890.033
Zebrafish Mouse Fly
positive regulation of developmental growthGO:00486393540.033
Fly
intracellular signal transductionGO:0035556960.033
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459351340.033
protein complex biogenesisGO:00702711860.032
regulation of behaviorGO:0050795970.032
anatomical structure formation involved in morphogenesisGO:00486462500.032
positive regulation of signalingGO:0023056660.031
muscle structure developmentGO:00610611910.031
nucleobase containing compound catabolic processGO:00346551140.031
macromolecular complex subunit organizationGO:00439333200.031
protein complex subunit organizationGO:00718222800.030
negative regulation of multicellular organismal processGO:00512412360.030
phagocytosisGO:00069091150.029
Worm
cellular response to chemical stimulusGO:00708871290.029
histone modificationGO:0016570300.029
glycosyl compound metabolic processGO:19016571000.028
microtubule based processGO:00070171820.028
transcription dna templatedGO:00063511680.028
regulation of intracellular signal transductionGO:1902531770.028
regulation of signalingGO:00230511720.028
Fly
positive regulation of cellular metabolic processGO:00313251780.027
Mouse Fly
carbohydrate derivative metabolic processGO:19011351410.027
cell motilityGO:00488703130.027
regulation of multi organism processGO:0043900690.027
single organism signalingGO:00447004010.027
Mouse Fly
chemotaxisGO:00069351200.026
cell projection morphogenesisGO:00488581480.026
Zebrafish Fly
positive regulation of multicellular organism growthGO:00400183520.025
positive regulation of macromolecule metabolic processGO:00106041490.025
Mouse Fly
reproductive system developmentGO:00614588500.025
nucleoside triphosphate metabolic processGO:0009141870.025
cellular ketone metabolic processGO:0042180140.024
regulation of protein metabolic processGO:0051246810.024
Mouse Fly
muscle cell differentiationGO:00426921710.024
defense responseGO:00069522960.024
regulation of nucleocytoplasmic transportGO:004682230.024
dna metabolic processGO:0006259740.024
Mouse
engulfment of apoptotic cellGO:0043652940.023
adult behaviorGO:003053430.023
ion transmembrane transportGO:0034220910.023
organelle localizationGO:00516401270.023
regulation of localizationGO:00328791940.023
Worm
gonad developmentGO:00084068400.023
organic acid metabolic processGO:0006082470.023
regulation of transcription from rna polymerase ii promoterGO:00063571450.023
cell morphogenesis involved in differentiationGO:00009041120.022
Zebrafish Fly
regulation of synaptic plasticityGO:004816710.022
Fly
regulation of nucleic acid templated transcriptionGO:19035061650.022
organophosphate catabolic processGO:0046434810.022
membrane invaginationGO:0010324980.022
Worm
protein complex assemblyGO:00064611860.022
internal peptidyl lysine acetylationGO:001839330.022
actin filament based processGO:00300291910.022
negative regulation of macromolecule biosynthetic processGO:0010558650.022
negative regulation of cellular biosynthetic processGO:0031327650.021
phagocytosis engulfmentGO:0006911980.021
Worm
transcription from rna polymerase ii promoterGO:00063661490.021
regulation of kinase activityGO:0043549290.021
Mouse
actin cytoskeleton organizationGO:00300361840.021
apoptotic cell clearanceGO:00432771110.021
Worm
positive regulation of nucleic acid templated transcriptionGO:19035081020.021
dna repairGO:0006281230.020
cellular component movementGO:00069283880.020
axonal fasciculationGO:0007413790.020
regulation of neuron differentiationGO:0045664400.020
Zebrafish Fly
phosphate containing compound metabolic processGO:00067962320.020
Human Mouse Worm Fly
mitotic sister chromatid segregationGO:0000070380.020
negative regulation of nitrogen compound metabolic processGO:0051172630.020
mitotic cell cycle processGO:19030471940.020
single organism biosynthetic processGO:0044711910.020
Human Mouse Worm Fly
sister chromatid segregationGO:0000819460.020
phosphorylationGO:00163101160.019
Human Mouse Fly
single organism behaviorGO:0044708830.019
purine ribonucleotide metabolic processGO:0009150950.019
cellular response to stressGO:00335541620.019
Fly
system processGO:00030081360.019
cellular protein complex assemblyGO:00436231780.019
oxoacid metabolic processGO:0043436470.019
small gtpase mediated signal transductionGO:0007264320.019
nucleotide metabolic processGO:00091171080.018
regulation of small gtpase mediated signal transductionGO:0051056410.018
protein oligomerizationGO:005125940.018
purine ribonucleoside triphosphate metabolic processGO:0009205870.018
positive regulation of signal transductionGO:0009967400.018
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.018
macromolecular complex assemblyGO:00650031930.018
sensory organ morphogenesisGO:009059620.018
single organism catabolic processGO:00447121290.017
negative regulation of rna metabolic processGO:0051253530.017
response to peptide hormoneGO:0043434140.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.017
protein phosphorylationGO:0006468850.017
Mouse
regulation of phosphate metabolic processGO:0019220810.016
Mouse
purine nucleoside metabolic processGO:0042278920.016
positive regulation of nucleoside metabolic processGO:0045979280.016
cellular response to dna damage stimulusGO:0006974410.016
covalent chromatin modificationGO:0016569300.016
axon guidanceGO:0007411820.016
regulation of phosphorus metabolic processGO:0051174810.016
Mouse
regulation of protein serine threonine kinase activityGO:0071900180.016
purine containing compound metabolic processGO:0072521950.016
localization of cellGO:00516743130.016
negative regulation of neurogenesisGO:005076840.016
positive regulation of developmental processGO:00510944080.016
Fly
meiotic nuclear divisionGO:00071263000.016
organelle fissionGO:00482853630.015
response to ionizing radiationGO:0010212160.015
Worm
organonitrogen compound biosynthetic processGO:1901566440.015
regulation of cell differentiationGO:0045595810.015
Zebrafish Fly
cell type specific apoptotic processGO:009728540.015
Mouse
meiotic cell cycleGO:00513213350.015
regulation of cellular ketone metabolic processGO:001056530.015
post embryonic organ developmentGO:00485693360.015
regulation of cellular protein metabolic processGO:0032268750.014
Mouse Fly
intracellular transportGO:0046907770.014
single organism intracellular transportGO:1902582700.014
regulation of apoptotic signaling pathwayGO:200123310.014
regulation of sequence specific dna binding transcription factor activityGO:005109030.014
regulation of apoptotic processGO:0042981360.014
Human Mouse
regulation of cell proliferationGO:00421271050.014
Fly
striated muscle cell developmentGO:00550021570.014
ribonucleoside triphosphate metabolic processGO:0009199870.014
gtp metabolic processGO:0046039460.014
regulation of multicellular organism growthGO:00400143730.014
Mouse Fly
purine nucleotide catabolic processGO:0006195750.014
organic substance catabolic processGO:19015752940.014
lipid modificationGO:003025840.014
Human Mouse Fly
response to insulinGO:0032868140.014
cellular response to organonitrogen compoundGO:0071417140.014
regulation of reproductive processGO:2000241660.014
cell cell signalingGO:00072671180.013
Fly
glycosyl compound catabolic processGO:1901658790.013
heterocycle catabolic processGO:00467001190.013
cellular response to abiotic stimulusGO:007121440.013
positive regulation of cell deathGO:0010942380.013
regulation of transportGO:0051049910.013
Worm
innate immune responseGO:00450871900.013
negative regulation of cell communicationGO:0010648610.013
Fly
establishment of localization in cellGO:00516493180.013
dna recombinationGO:0006310190.013
transmembrane transportGO:00550851100.012
oocyte differentiationGO:0009994450.012
developmental cell growthGO:0048588390.012
Zebrafish
regulation of programmed cell deathGO:0043067500.012
Human Mouse
organophosphate metabolic processGO:00196371250.012
Human Mouse Worm Fly
cell recognitionGO:0008037850.012
carboxylic acid metabolic processGO:0019752340.012
nucleotide catabolic processGO:0009166770.012
regulation of meiotic cell cycleGO:00514451360.012
regulation of pharyngeal pumpingGO:0043051360.012
signal transduction by phosphorylationGO:0023014310.011
regulation of lipid metabolic processGO:001921640.011
nucleobase containing small molecule metabolic processGO:00550861150.011
ras protein signal transductionGO:0007265310.011
mitotic nuclear divisionGO:0007067890.011
positive regulation of neurogenesisGO:005076940.011
single organism membrane organizationGO:0044802350.011
response to nitrogen compoundGO:1901698250.011
male sex differentiationGO:0046661860.011
adult locomotory behaviorGO:000834410.011
positive regulation of rna metabolic processGO:00512541030.011
negative regulation of dna recombinationGO:004591040.011
response to oxygen containing compoundGO:1901700440.010
negative regulation of signalingGO:0023057610.010
Fly
chromatin modificationGO:0016568320.010
regulation of neuron projection developmentGO:0010975310.010
Zebrafish Fly
regulation of organelle organizationGO:00330431640.010
single organism carbohydrate metabolic processGO:0044723290.010
Mouse
behavioral response to ethanolGO:004814910.010
carbohydrate derivative catabolic processGO:1901136820.010
cellular macromolecule localizationGO:0070727750.010
myosin filament assemblyGO:00310341380.010

age-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of mental healthDOID:15000.020
developmental disorder of mental healthDOID:006003700.020
cancerDOID:16200.020
Human
disease of cellular proliferationDOID:1456600.020
Human
organ system cancerDOID:005068600.014
Human
disease of anatomical entityDOID:700.011
Human