Caenorhabditis elegans

141 known processes

wrn-1 (CELE_F18C5.2)

Protein WRN-1

wrn-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.537
embryo development ending in birth or egg hatchingGO:000979229920.473
single organism transportGO:00447654470.389
Human
vesicle mediated transportGO:00161928520.315
locomotionGO:004001116340.277
response to organic substanceGO:00100331310.276
phosphate containing compound metabolic processGO:00067962320.234
transportGO:000681010930.212
Human
developmental growthGO:00485894120.204
regulation of multicellular organismal processGO:00512397260.179
response to abiotic stimulusGO:00096281520.143
organic substance biosynthetic processGO:19015763230.138
Human Mouse
post embryonic developmentGO:000979121520.136
organic substance catabolic processGO:19015752940.133
growthGO:00400075620.133
cellular response to organic substanceGO:00713101190.130
positive regulation of multicellular organismal processGO:00512404170.128
macromolecule localizationGO:00330367710.122
regulation of developmental growthGO:00486383890.118
regulation of growthGO:00400084090.117
cellular localizationGO:00516413600.110
Human
cell cycle processGO:00224024820.108
programmed cell deathGO:00125015000.105
Human
small molecule metabolic processGO:00442811860.104
heterocycle catabolic processGO:00467001190.097
nucleobase containing compound catabolic processGO:00346551140.097
cell deathGO:00082195470.094
Human
deathGO:00162655470.092
Human
response to chemicalGO:00422213560.087
single organism organelle organizationGO:19025895010.086
Human Mouse
mitotic cell cycle processGO:19030471940.086
positive regulation of metabolic processGO:00098931870.082
Human
single organism localizationGO:19025785180.081
Human
regulation of nucleobase containing compound metabolic processGO:00192192220.078
catabolic processGO:00090563180.078
secretion by cellGO:00329401380.075
purine ribonucleoside catabolic processGO:0046130750.075
lipid localizationGO:00108765730.071
signal transductionGO:00071653170.070
regulation of nitrogen compound metabolic processGO:00511712220.069
purine containing compound catabolic processGO:0072523750.068
establishment of localization in cellGO:00516493180.068
Human
regulation of biological qualityGO:00650087410.067
Human Mouse
meiotic nuclear divisionGO:00071263000.066
positive regulation of cellular processGO:00485223320.066
regulation of cell morphogenesisGO:0022604400.065
cellular response to chemical stimulusGO:00708871290.065
positive regulation of growthGO:00459273690.065
protein metabolic processGO:00195384220.064
enzyme linked receptor protein signaling pathwayGO:0007167500.063
positive regulation of developmental processGO:00510944080.063
lipid storageGO:00199155650.062
protein localizationGO:00081042050.062
dna recombinationGO:0006310190.061
regulation of macromolecule metabolic processGO:00602554210.059
maintenance of locationGO:00512355800.057
cytoskeleton organizationGO:00070103390.057
neurogenesisGO:00220082360.054
nucleoside triphosphate metabolic processGO:0009141870.054
endocytosisGO:00068978190.052
organelle organizationGO:00069967830.052
Human Mouse
organophosphate metabolic processGO:00196371250.051
neuron recognitionGO:0008038830.051
regulation of locomotionGO:00400121610.051
biosynthetic processGO:00090583230.051
Human Mouse
regulation of developmental processGO:00507936840.050
regulation of multicellular organism growthGO:00400143730.050
gonad developmentGO:00084068400.050
nucleic acid metabolic processGO:00903042990.049
membrane organizationGO:00610241350.049
cell cycleGO:00070495260.049
multicellular organism growthGO:00352643850.048
purine nucleotide catabolic processGO:0006195750.047
single organism signalingGO:00447004010.047
positive regulation of macromolecule metabolic processGO:00106041490.046
determination of adult lifespanGO:00083408120.046
regulation of gene expressionGO:00104683660.045
negative regulation of macromolecule metabolic processGO:00106052290.044
cell surface receptor signaling pathwayGO:00071661490.044
transcription dna templatedGO:00063511680.044
multicellular organismal agingGO:00102598120.043
purine nucleoside triphosphate catabolic processGO:0009146720.042
positive regulation of cellular metabolic processGO:00313251780.042
generation of neuronsGO:00486992350.041
protein modification processGO:00362112070.041
regulation of cellular component organizationGO:00511282480.041
phosphorus metabolic processGO:00067932320.041
establishment of localizationGO:005123411710.040
Human
negative regulation of metabolic processGO:00098922400.039
cellular protein modification processGO:00064642070.039
macromolecular complex subunit organizationGO:00439333200.039
purine ribonucleotide metabolic processGO:0009150950.039
regulation of gene expression epigeneticGO:00400291630.039
cell projection morphogenesisGO:00488581480.039
signalingGO:00230524010.038
regulation of metabolic processGO:00192224780.038
Human
organ developmentGO:004851311020.038
cellular protein metabolic processGO:00442672790.037
ribonucleoside triphosphate metabolic processGO:0009199870.036
purine nucleotide metabolic processGO:0006163950.036
dna repairGO:0006281230.035
Human
secretionGO:00469031470.035
organonitrogen compound metabolic processGO:19015641510.035
neuron differentiationGO:00301822170.034
reproductive system developmentGO:00614588500.034
positive regulation of multicellular organism growthGO:00400183520.033
cell migrationGO:00164773060.033
regulation of multicellular organismal developmentGO:20000263170.032
organic cyclic compound catabolic processGO:19013611190.032
purine nucleoside metabolic processGO:0042278920.032
regulation of cellular metabolic processGO:00313233050.032
positive regulation of developmental growthGO:00486393540.032
genitalia developmentGO:00488067410.032
nucleoside phosphate metabolic processGO:00067531080.031
cell motilityGO:00488703130.030
chromosome organizationGO:00512761040.030
Human Mouse
hermaphrodite genitalia developmentGO:00400357340.029
gene expressionGO:00104674120.029
positive regulation of molecular functionGO:0044093610.029
Human
purine nucleoside monophosphate catabolic processGO:0009128280.029
negative regulation of biological processGO:00485195670.028
axon developmentGO:00615641630.028
posttranscriptional gene silencingGO:00164411430.028
regulation of cellular biosynthetic processGO:00313261890.028
neuron projection developmentGO:00311751870.028
body morphogenesisGO:00101716200.026
regulation of rna metabolic processGO:00512521730.026
nervous system developmentGO:00073992530.026
glycosyl compound metabolic processGO:19016571000.025
rna interferenceGO:00162461370.025
apoptotic processGO:00069154780.025
Human
macromolecule modificationGO:00434122180.025
meiotic cell cycleGO:00513213350.024
cellular macromolecule localizationGO:0070727750.024
cellular macromolecule biosynthetic processGO:00346452470.024
Human Mouse
cellular response to inorganic substanceGO:007124130.024
cell developmentGO:00484686960.024
glycosyl compound catabolic processGO:1901658790.024
purine ribonucleotide catabolic processGO:0009154750.023
oxoacid metabolic processGO:0043436470.023
regulation of hydrolase activityGO:0051336450.023
Human
regulation of phosphorus metabolic processGO:0051174810.023
carboxylic acid metabolic processGO:0019752340.023
cell cell signalingGO:00072671180.023
neuron developmentGO:00486661990.023
positive regulation of catalytic activityGO:0043085590.022
Human
cell projection organizationGO:00300302310.022
reproductive structure developmentGO:00486088500.022
negative regulation of cellular processGO:00485232390.022
response to inorganic substanceGO:0010035500.021
ribonucleoside metabolic processGO:0009119980.021
nucleotide catabolic processGO:0009166770.021
cellular protein localizationGO:0034613750.021
regulation of synapse assemblyGO:005196320.021
organophosphate catabolic processGO:0046434810.021
ribose phosphate metabolic processGO:0019693990.021
posttranscriptional regulation of gene expressionGO:00106081660.020
organonitrogen compound catabolic processGO:1901565900.020
regulation of transcription dna templatedGO:00063551640.020
purine ribonucleoside triphosphate metabolic processGO:0009205870.020
posttranscriptional gene silencing by rnaGO:00351941430.020
intracellular signal transductionGO:0035556960.019
nucleobase containing compound metabolic processGO:00061394060.019
nucleobase containing small molecule metabolic processGO:00550861150.019
meiotic cell cycle processGO:19030461700.019
axonal fasciculationGO:0007413790.019
cellular component morphogenesisGO:00329893180.019
regulation of post embryonic developmentGO:00485802600.019
purine ribonucleoside triphosphate catabolic processGO:0009207720.019
ribonucleoside catabolic processGO:0042454770.018
head developmentGO:006032210.018
cellular catabolic processGO:00442481990.018
regulation of cell cycle processGO:00105641450.018
microtubule based processGO:00070171820.018
single organism reproductive processGO:004470211960.018
regulation of response to stimulusGO:00485832430.018
cellular nitrogen compound biosynthetic processGO:00442711920.018
Human
negative regulation of cell cycleGO:0045786530.018
regulation of signal transductionGO:00099661350.018
negative regulation of gene expressionGO:00106292170.018
response to oxygen containing compoundGO:1901700440.018
neuromuscular junction developmentGO:000752820.018
developmental process involved in reproductionGO:000300611650.018
macromolecule biosynthetic processGO:00090592500.018
Human Mouse
vulval developmentGO:00400253330.018
multicellular organismal reproductive processGO:00486098150.018
nucleoside triphosphate catabolic processGO:0009143720.018
carbohydrate derivative metabolic processGO:19011351410.017
single organism biosynthetic processGO:0044711910.017
organic acid metabolic processGO:0006082470.017
chromosome segregationGO:00070591800.017
cell type specific apoptotic processGO:009728540.017
regulation of localizationGO:00328791940.017
regulation of cell cycleGO:00517261940.017
regulation of macromolecule biosynthetic processGO:00105561890.017
regulation of primary metabolic processGO:00800902920.016
cellular response to dna damage stimulusGO:0006974410.016
Human
establishment or maintenance of cell polarityGO:0007163630.016
lipid metabolic processGO:0006629770.016
regulation of meiotic cell cycleGO:00514451360.016
regulation of vulval developmentGO:00400282480.016
positive regulation of nitrogen compound metabolic processGO:00511731340.016
purine containing compound metabolic processGO:0072521950.016
ribonucleotide metabolic processGO:0009259990.016
cellular component biogenesisGO:00440852970.016
post embryonic organ developmentGO:00485693360.016
phosphorylationGO:00163101160.016
cell substrate adhesionGO:003158910.016
negative regulation of cellular metabolic processGO:0031324950.015
nucleoside monophosphate metabolic processGO:0009123460.015
axonogenesisGO:00074091020.015
regulation of biosynthetic processGO:00098891890.015
actin cytoskeleton organizationGO:00300361840.015
regulation of cell sizeGO:0008361300.015
regulation of nematode larval developmentGO:00610622600.015
gene silencing by rnaGO:00310471430.015
rna metabolic processGO:00160702280.015
regulation of cell communicationGO:00106461760.015
carbohydrate derivative catabolic processGO:1901136820.015
organelle fissionGO:00482853630.015
inductive cell migrationGO:00400391450.015
regulation of signalingGO:00230511720.015
regulation of transposition dna mediatedGO:000033730.014
aromatic compound catabolic processGO:00194391160.014
protein transportGO:0015031450.014
intracellular transportGO:0046907770.014
Human
negative regulation of nucleobase containing compound metabolic processGO:0045934630.014
chemical homeostasisGO:0048878290.014
receptor mediated endocytosisGO:00068987150.014
cellular nitrogen compound catabolic processGO:00442701190.014
dna duplex unwindingGO:003250830.014
ribonucleotide catabolic processGO:0009261750.014
single organism membrane organizationGO:0044802350.014
purine nucleoside triphosphate metabolic processGO:0009144870.014
regulation of catalytic activityGO:0050790780.014
Human
actin filament based processGO:00300291910.014
cellular response to endogenous stimulusGO:0071495320.014
regulation of mitotic cell cycleGO:0007346760.013
cuticle developmentGO:00423351000.013
regulation of cellular ketone metabolic processGO:001056530.013
response to peptide hormoneGO:0043434140.013
purine nucleoside catabolic processGO:0006152750.013
response to bacteriumGO:0009617860.013
synaptic growth at neuromuscular junctionGO:005112410.013
nucleotide metabolic processGO:00091171080.013
cellular component assemblyGO:00226072930.013
organic substance transportGO:00717021130.013
response to woundingGO:000961140.013
cell divisionGO:00513012620.013
membrane invaginationGO:0010324980.013
regulation of cellular amine metabolic processGO:003323800.013
multi organism reproductive processGO:00447038670.013
g1 s transition of mitotic cell cycleGO:000008220.012
cell cycle g1 s phase transitionGO:004484320.012
muscle tissue developmentGO:006053710.012
embryonic morphogenesisGO:00485981520.012
nucleoside metabolic processGO:0009116990.012
dna metabolic processGO:0006259740.012
negative regulation of gene expression epigeneticGO:004581420.012
amine metabolic processGO:0009308150.012
behaviorGO:00076105270.012
regulation of anatomical structure morphogenesisGO:0022603510.012
atp metabolic processGO:0046034420.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.012
multicellular organism reproductionGO:00325048190.012
cellular biosynthetic processGO:00442493150.012
Human Mouse
oocyte differentiationGO:0009994450.012
regulation of phosphate metabolic processGO:0019220810.012
digestive system developmentGO:00551231220.012
cellular response to stressGO:00335541620.012
Human
cell cycle g2 m phase transitionGO:004483910.012
regulation of transcription from rna polymerase ii promoterGO:00063571450.012
collagen and cuticulin based cuticle developmentGO:0040002990.011
cell morphogenesis involved in differentiationGO:00009041120.011
tissue developmentGO:00098881120.011
protein oligomerizationGO:005125940.011
negative regulation of developmental processGO:00510932270.011
regulation of nucleic acid templated transcriptionGO:19035061650.011
single organism catabolic processGO:00447121290.011
apoptotic cell clearanceGO:00432771110.011
gamete generationGO:00072764610.011
cell recognitionGO:0008037850.011
cellular amino acid metabolic processGO:0006520150.011
positive regulation of cell cycleGO:0045787550.011
response to metal ionGO:0010038330.011
regulation of organelle organizationGO:00330431640.011
development of primary sexual characteristicsGO:00451378400.011
macromolecule catabolic processGO:00090572020.011
nucleoside phosphate catabolic processGO:1901292770.011
rna biosynthetic processGO:00327741690.010
regulation of molecular functionGO:0065009890.010
Human
single organism cellular localizationGO:1902580720.010
localization of cellGO:00516743130.010
ovipositionGO:00189913640.010
negative regulation of dna recombinationGO:004591040.010
aromatic compound biosynthetic processGO:00194381920.010
Human
cellular response to insulin stimulusGO:0032869140.010
positive regulation of meiotic cell cycleGO:0051446470.010

wrn-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
disease of cellular proliferationDOID:1456600.026
organ system cancerDOID:005068600.015
cancerDOID:16200.015