Caenorhabditis elegans

22 known processes

pis-1 (CELE_T13F2.3)

Protein PIS-1

pis-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna biosynthetic processGO:20011411650.683
Human Mouse
regulation of macromolecule metabolic processGO:00602554210.674
Human Mouse
gene expressionGO:00104674120.537
Human Mouse
embryo development ending in birth or egg hatchingGO:000979229920.397
regulation of rna metabolic processGO:00512521730.377
Human Mouse
negative regulation of vulval developmentGO:00400272060.352
single organism organelle organizationGO:19025895010.344
Human Mouse
embryo developmentGO:000979030520.301
locomotionGO:004001116340.293
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459351340.291
Human Mouse
positive regulation of metabolic processGO:00098931870.276
Human Mouse
negative regulation of nematode larval developmentGO:00610642080.265
negative regulation of biological processGO:00485195670.258
regulation of gene expressionGO:00104683660.211
Human Mouse
cell cycleGO:00070495260.201
regulation of vulval developmentGO:00400282480.195
negative regulation of post embryonic developmentGO:00485812080.194
establishment of localizationGO:005123411710.190
transportGO:000681010930.187
macromolecular complex subunit organizationGO:00439333200.182
Human Mouse
muscle tissue developmentGO:006053710.174
regulation of primary metabolic processGO:00800902920.166
Human Mouse
cellular biosynthetic processGO:00442493150.153
Human Mouse
organ developmentGO:004851311020.133
Mouse
receptor mediated endocytosisGO:00068987150.130
regulation of macromolecule biosynthetic processGO:00105561890.130
Human Mouse
organelle fissionGO:00482853630.123
cellular component biogenesisGO:00440852970.120
Human Mouse
vesicle mediated transportGO:00161928520.119
negative regulation of macromolecule metabolic processGO:00106052290.117
cellular component assemblyGO:00226072930.117
Human Mouse
regulation of metabolic processGO:00192224780.116
Human Mouse
regulation of gene expression epigeneticGO:00400291630.108
negative regulation of multicellular organismal processGO:00512412360.105
single organism reproductive processGO:004470211960.104
rna metabolic processGO:00160702280.103
Human Mouse
purine nucleoside triphosphate catabolic processGO:0009146720.102
organonitrogen compound metabolic processGO:19015641510.102
cell migrationGO:00164773060.100
Mouse
regulation of biological qualityGO:00650087410.095
post embryonic developmentGO:000979121520.093
heterocycle biosynthetic processGO:00181301870.091
Human Mouse
multi organism behaviorGO:00517053890.089
regulation of multicellular organismal processGO:00512397260.088
nucleobase containing compound metabolic processGO:00061394060.086
Human Mouse
tissue developmentGO:00098881120.083
Mouse
small molecule metabolic processGO:00442811860.082
sex differentiationGO:00075489090.080
regulation of cell cycleGO:00517261940.078
regulation of nitrogen compound metabolic processGO:00511712220.077
Human Mouse
regulation of developmental processGO:00507936840.076
positive regulation of cellular metabolic processGO:00313251780.076
Human Mouse
protein complex subunit organizationGO:00718222800.076
Human Mouse
innate immune responseGO:00450871900.075
purine nucleoside catabolic processGO:0006152750.075
macromolecule localizationGO:00330367710.073
regulation of organelle organizationGO:00330431640.072
Mouse
posttranscriptional regulation of gene expressionGO:00106081660.072
nucleoside catabolic processGO:0009164780.071
cellular component movementGO:00069283880.071
Mouse
regulation of biosynthetic processGO:00098891890.070
Human Mouse
molting cycle collagen and cuticulin based cuticleGO:00189962810.069
positive regulation of nucleic acid templated transcriptionGO:19035081020.066
Human Mouse
macromolecule biosynthetic processGO:00090592500.066
Human Mouse
cell motilityGO:00488703130.066
Mouse
cell part morphogenesisGO:00329901520.065
regulation of post embryonic developmentGO:00485802600.065
positive regulation of nitrogen compound metabolic processGO:00511731340.064
Human Mouse
regulation of cell proliferationGO:00421271050.063
regulation of nucleic acid templated transcriptionGO:19035061650.063
Human Mouse
biosynthetic processGO:00090583230.063
Human Mouse
endocytosisGO:00068978190.062
glycosyl compound metabolic processGO:19016571000.062
establishment of localization in cellGO:00516493180.061
apoptotic processGO:00069154780.061
regulation of nucleobase containing compound metabolic processGO:00192192220.061
Human Mouse
single organism transportGO:00447654470.061
cell projection organizationGO:00300302310.060
lipid storageGO:00199155650.059
single organism localizationGO:19025785180.058
maintenance of locationGO:00512355800.058
transcription dna templatedGO:00063511680.058
Human Mouse
reproductive behaviorGO:00190983870.057
skeletal muscle organ developmentGO:006053830.056
muscle structure developmentGO:00610611910.056
purine nucleotide catabolic processGO:0006195750.054
multi organism reproductive processGO:00447038670.054
phosphorus metabolic processGO:00067932320.054
regulation of nematode larval developmentGO:00610622600.053
development of primary sexual characteristicsGO:00451378400.053
organic substance biosynthetic processGO:19015763230.053
Human Mouse
rna localizationGO:000640330.052
regulation of locomotionGO:00400121610.052
deathGO:00162655470.052
regulation of multicellular organismal developmentGO:20000263170.051
Mouse
carbohydrate derivative metabolic processGO:19011351410.049
hermaphrodite genitalia developmentGO:00400357340.048
lipid localizationGO:00108765730.048
heterocycle catabolic processGO:00467001190.047
regulation of cellular component organizationGO:00511282480.047
Human Mouse
axon developmentGO:00615641630.047
multi organism reproductive behaviorGO:00447053870.046
ribonucleoside triphosphate metabolic processGO:0009199870.046
organelle organizationGO:00069967830.046
Human Mouse
inductive cell migrationGO:00400391450.046
negative regulation of gene expression epigeneticGO:004581420.046
sexual reproductionGO:00199535460.045
cytokinesisGO:0000910800.045
cellular component morphogenesisGO:00329893180.044
cell morphogenesis involved in neuron differentiationGO:00486671110.044
neuron projection developmentGO:00311751870.044
multicellular organismal agingGO:00102598120.043
protein metabolic processGO:00195384220.043
Human Mouse
cellular response to dna damage stimulusGO:0006974410.042
Human Mouse
ovipositionGO:00189913640.042
multicellular organism reproductionGO:00325048190.042
organic cyclic compound biosynthetic processGO:19013621950.041
Human Mouse
meiotic cell cycleGO:00513213350.041
cellular macromolecule biosynthetic processGO:00346452470.041
Human Mouse
nucleotide metabolic processGO:00091171080.041
cell cycle processGO:00224024820.040
meiotic chromosome segregationGO:00451321390.040
chromosome organizationGO:00512761040.040
Human Mouse
reproductive system developmentGO:00614588500.040
cellular component assembly involved in morphogenesisGO:00109271830.039
cytoskeleton organizationGO:00070103390.038
vulval developmentGO:00400253330.038
organic substance transportGO:00717021130.038
meiotic nuclear divisionGO:00071263000.037
organophosphate metabolic processGO:00196371250.037
nucleoside triphosphate catabolic processGO:0009143720.037
post embryonic organ developmentGO:00485693360.037
multicellular organismal reproductive processGO:00486098150.037
nucleic acid metabolic processGO:00903042990.036
Human Mouse
mitotic cell cycle processGO:19030471940.036
ribonucleotide catabolic processGO:0009261750.036
regulation of cellular macromolecule biosynthetic processGO:20001121880.036
Human Mouse
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.035
Human Mouse
positive regulation of cellular biosynthetic processGO:00313281090.035
Human Mouse
rna biosynthetic processGO:00327741690.034
Human Mouse
regulation of meiosisGO:0040020940.034
negative regulation of cellular metabolic processGO:0031324950.033
ribose phosphate metabolic processGO:0019693990.033
regulation of cell motilityGO:2000145570.033
negative regulation of metabolic processGO:00098922400.033
anatomical structure formation involved in morphogenesisGO:00486462500.033
purine ribonucleotide catabolic processGO:0009154750.033
genitalia developmentGO:00488067410.031
actin filament based processGO:00300291910.031
carbohydrate derivative catabolic processGO:1901136820.031
nucleoside phosphate catabolic processGO:1901292770.031
regulation of nuclear divisionGO:00517831150.031
purine ribonucleotide metabolic processGO:0009150950.030
spindle localizationGO:0051653510.030
positive regulation of protein metabolic processGO:0051247450.030
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063571450.030
Human Mouse
generation of neuronsGO:00486992350.030
organelle localizationGO:00516401270.030
organelle assemblyGO:00709252140.029
cell divisionGO:00513012620.029
gonad developmentGO:00084068400.029
regulation of chromosome organizationGO:0033044200.029
Mouse
regulation of cellular metabolic processGO:00313233050.029
Human Mouse
negative regulation of developmental processGO:00510932270.029
rna interferenceGO:00162461370.028
immune responseGO:00069551920.028
Mouse
positive regulation of gtpase activityGO:0043547280.028
chromosome segregationGO:00070591800.028
regulation of multicellular organism growthGO:00400143730.028
female gamete generationGO:00072922540.028
molting cycleGO:00423032810.028
cell proliferationGO:00082831160.028
organ morphogenesisGO:0009887670.028
aromatic compound catabolic processGO:00194391160.028
ribonucleoside catabolic processGO:0042454770.028
agingGO:00075688120.028
nucleotide catabolic processGO:0009166770.028
actomyosin structure organizationGO:00310321540.028
striated muscle cell differentiationGO:00511461580.028
organophosphate catabolic processGO:0046434810.027
localization of cellGO:00516743130.027
Mouse
programmed cell deathGO:00125015000.027
regulation of ras protein signal transductionGO:0046578410.026
attachment of spindle microtubules to kinetochoreGO:000860880.026
head developmentGO:006032210.026
nucleoside metabolic processGO:0009116990.026
glycosyl compound catabolic processGO:1901658790.026
signalingGO:00230524010.026
Human
regulation of cellular biosynthetic processGO:00313261890.026
Human Mouse
body morphogenesisGO:00101716200.026
reproductive structure developmentGO:00486088500.025
developmental process involved in reproductionGO:000300611650.025
regulation of cell cycle processGO:00105641450.025
cell developmentGO:00484686960.025
positive regulation of macromolecule biosynthetic processGO:00105571090.025
Human Mouse
chromatin remodelingGO:000633820.024
catabolic processGO:00090563180.024
cellular localizationGO:00516413600.024
regulation of molecular functionGO:0065009890.024
cellular ketone metabolic processGO:0042180140.024
nucleobase containing small molecule metabolic processGO:00550861150.024
regulation of cellular ketone metabolic processGO:001056530.024
establishment of cell polarityGO:0030010460.023
dna metabolic processGO:0006259740.023
Mouse
multicellular organismal reproductive behaviorGO:00330573840.023
negative regulation of transcription dna templatedGO:0045892530.023
nucleoside phosphate metabolic processGO:00067531080.023
myofibril assemblyGO:00302391540.022
purine ribonucleoside triphosphate catabolic processGO:0009207720.022
positive regulation of cellular processGO:00485223320.022
Human Mouse
small gtpase mediated signal transductionGO:0007264320.022
maintenance of protein locationGO:0045185150.022
regionalizationGO:0003002310.022
purine ribonucleoside triphosphate metabolic processGO:0009205870.022
behaviorGO:00076105270.022
cellular nitrogen compound catabolic processGO:00442701190.022
actin cytoskeleton organizationGO:00300361840.022
neuron developmentGO:00486661990.021
cellular catabolic processGO:00442481990.021
purine nucleotide metabolic processGO:0006163950.021
cell deathGO:00082195470.021
ribonucleoside metabolic processGO:0009119980.021
establishment of mitotic spindle orientationGO:0000132280.021
macromolecule modificationGO:00434122180.021
Human Mouse
meiotic cell cycle processGO:19030461700.020
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.020
positive regulation of nucleoside metabolic processGO:0045979280.020
purine nucleoside triphosphate metabolic processGO:0009144870.020
cell recognitionGO:0008037850.020
regulation of phosphorus metabolic processGO:0051174810.020
multi multicellular organism processGO:00447063900.020
taxisGO:00423301280.020
purine nucleoside metabolic processGO:0042278920.020
positive regulation of multicellular organism growthGO:00400183520.020
nucleic acid templated transcriptionGO:00976591690.020
Human Mouse
positive regulation of catabolic processGO:0009896380.020
gene silencing by rnaGO:00310471430.019
nitrogen compound transportGO:0071705490.019
determination of adult lifespanGO:00083408120.019
posttranscriptional gene silencing by rnaGO:00351941430.019
digestive tract developmentGO:00485651220.019
muscle cell developmentGO:00550011580.019
cellular protein modification processGO:00064642070.019
Human Mouse
intracellular signal transductionGO:0035556960.019
Human
digestive system developmentGO:00551231220.019
positive regulation of nucleotide metabolic processGO:0045981280.019
regulation of cytoskeleton organizationGO:0051493410.019
gene silencingGO:00164581430.019
membrane organizationGO:00610241350.019
ribonucleoside triphosphate catabolic processGO:0009203720.018
protein complex biogenesisGO:00702711860.018
Human Mouse
positive regulation of macromolecule metabolic processGO:00106041490.018
Human Mouse
regulation of developmental growthGO:00486383890.018
phosphate containing compound metabolic processGO:00067962320.018
regulation of nucleotide catabolic processGO:0030811350.018
attachment of mitotic spindle microtubules to kinetochoreGO:005131560.017
establishment of organelle localizationGO:00516561230.017
negative regulation of rna biosynthetic processGO:1902679530.017
ribonucleotide metabolic processGO:0009259990.017
ras protein signal transductionGO:0007265310.017
positive regulation of transcription dna templatedGO:00458931020.017
Human Mouse
positive regulation of developmental processGO:00510944080.017
purine containing compound metabolic processGO:0072521950.017
muscle cell differentiationGO:00426921710.016
carboxylic acid metabolic processGO:0019752340.016
regulation of response to stimulusGO:00485832430.016
Mouse
cellular protein metabolic processGO:00442672790.016
Human Mouse
rna transportGO:005065830.016
male sex differentiationGO:0046661860.016
regulation of cell migrationGO:0030334550.016
cell fate commitmentGO:00451651390.016
cellular macromolecular complex assemblyGO:00346221840.016
negative regulation of rna metabolic processGO:0051253530.016
oogenesisGO:00484772290.015
regulation of cellular component movementGO:0051270620.015
developmental growthGO:00485894120.015
positive regulation of intracellular transportGO:003238820.015
cell morphogenesisGO:00009021630.015
regulation of meiotic cell cycleGO:00514451360.015
regulation of cellular protein metabolic processGO:0032268750.015
Mouse
positive regulation of nucleotide catabolic processGO:0030813280.015
protein localizationGO:00081042050.015
activation of ras gtpase activityGO:003285630.015
single organism signalingGO:00447004010.015
Human
embryonic morphogenesisGO:00485981520.015
organic acid metabolic processGO:0006082470.014
cellular protein complex assemblyGO:00436231780.014
nucleobase containing compound biosynthetic processGO:00346541840.014
Human Mouse
organonitrogen compound catabolic processGO:1901565900.014
secretion by cellGO:00329401380.014
negative regulation of gene expressionGO:00106292170.014
negative regulation of cellular processGO:00485232390.014
nervous system developmentGO:00073992530.014
multicellular organism growthGO:00352643850.014
microtubule based processGO:00070171820.014
regulation of apoptotic signaling pathwayGO:200123310.014
guanosine containing compound metabolic processGO:1901068490.014
regulation of transcription dna templatedGO:00063551640.014
Human Mouse
pattern specification processGO:0007389590.014
defense responseGO:00069522960.013
cell type specific apoptotic processGO:009728540.013
cellular amine metabolic processGO:0044106150.013
centrosomal and pronuclear rotationGO:003504760.013
establishment of rna localizationGO:005123630.013
regulation of cell divisionGO:00513021420.013
positive regulation of gtp catabolic processGO:0033126280.013
growthGO:00400075620.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.013
tube developmentGO:00352951260.013
nucleobase containing compound catabolic processGO:00346551140.013
positive regulation of purine nucleotide catabolic processGO:0033123280.013
signal transductionGO:00071653170.013
Human
negative regulation of macromolecule biosynthetic processGO:0010558650.013
cytoskeleton dependent cytokinesisGO:0061640350.013
positive regulation of catalytic activityGO:0043085590.013
chemotaxisGO:00069351200.013
internal peptidyl lysine acetylationGO:001839330.013
Mouse
peptidyl amino acid modificationGO:0018193580.013
Mouse
nucleoside triphosphate metabolic processGO:0009141870.013
neurogenesisGO:00220082360.012
guanosine containing compound catabolic processGO:1901069480.012
macromolecular complex assemblyGO:00650031930.012
Human Mouse
gamete generationGO:00072764610.012
germ cell developmentGO:00072813510.012
purine containing compound catabolic processGO:0072523750.012
cellular amino acid metabolic processGO:0006520150.012
regulation of chromatin modificationGO:190330820.012
Mouse
transcription from rna polymerase ii promoterGO:00063661490.012
Human Mouse
cell morphogenesis involved in differentiationGO:00009041120.012
purine ribonucleoside catabolic processGO:0046130750.012
regulation of small gtpase mediated signal transductionGO:0051056410.012
positive regulation of phosphorus metabolic processGO:0010562560.011
regulation of cell communicationGO:00106461760.011
apoptotic cell clearanceGO:00432771110.011
single organism catabolic processGO:00447121290.011
protein complex assemblyGO:00064611860.011
Human Mouse
protein modification processGO:00362112070.011
Human Mouse
regulation of gtp catabolic processGO:0033124320.011
negative regulation of nucleobase containing compound metabolic processGO:0045934630.011
male anatomical structure morphogenesisGO:0090598780.011
nuclear migrationGO:0007097540.011
nucleic acid transportGO:005065730.011
negative regulation of nucleic acid templated transcriptionGO:1903507530.011
establishment of spindle orientationGO:0051294340.011
organic cyclic compound catabolic processGO:19013611190.010
gtp catabolic processGO:0006184460.010
oxoacid metabolic processGO:0043436470.010
regulation of nucleoside metabolic processGO:0009118370.010
dosage compensation by hypoactivation of x chromosomeGO:0042464110.010
posttranscriptional gene silencingGO:00164411430.010

pis-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
Human
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
gastrointestinal system cancerDOID:311900.017
organ system cancerDOID:005068600.017
large intestine cancerDOID:567200.013
intestinal cancerDOID:1015500.013
nervous system diseaseDOID:86300.013
Human
colorectal cancerDOID:925600.010