Caenorhabditis elegans

64 known processes

him-10 (CELE_R12B2.4)

Protein HIM-10

him-10 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic cell cycle processGO:19030471940.882
mitotic sister chromatid segregationGO:0000070380.831
cell cycleGO:00070495260.710
single organism reproductive processGO:004470211960.669
development of primary sexual characteristicsGO:00451378400.633
attachment of spindle microtubules to kinetochoreGO:000860880.606
microtubule based processGO:00070171820.572
mitotic spindle organizationGO:0007052810.571
hermaphrodite genitalia developmentGO:00400357340.570
developmental process involved in reproductionGO:000300611650.556
embryo development ending in birth or egg hatchingGO:000979229920.555
sex differentiationGO:00075489090.551
sexual reproductionGO:00199535460.526
nucleic acid metabolic processGO:00903042990.515
multicellular organism reproductionGO:00325048190.511
reproductive system developmentGO:00614588500.509
multi organism reproductive processGO:00447038670.509
cell cycle processGO:00224024820.487
meiotic chromosome segregationGO:00451321390.473
cellular localizationGO:00516413600.459
gonad developmentGO:00084068400.457
sister chromatid segregationGO:0000819460.457
cell morphogenesisGO:00009021630.436
nucleobase containing compound metabolic processGO:00061394060.413
multicellular organismal reproductive processGO:00486098150.411
dna metabolic processGO:0006259740.379
microtubule cytoskeleton organization involved in mitosisGO:1902850120.378
gene expressionGO:00104674120.376
reproductive structure developmentGO:00486088500.372
embryo developmentGO:000979030520.370
meiotic cell cycleGO:00513213350.362
single organism organelle organizationGO:19025895010.327
organ developmentGO:004851311020.313
establishment of localizationGO:005123411710.306
gamete generationGO:00072764610.293
spindle organizationGO:0007051920.285
chromosome segregationGO:00070591800.283
organelle organizationGO:00069967830.276
cellular macromolecule biosynthetic processGO:00346452470.269
ovipositionGO:00189913640.266
negative regulation of biological processGO:00485195670.261
cell projection morphogenesisGO:00488581480.248
maintenance of location in cellGO:0051651120.242
mitotic nuclear divisionGO:0007067890.239
locomotionGO:004001116340.238
maintenance of protein location in cellGO:0032507120.236
organelle fissionGO:00482853630.231
neuron projection developmentGO:00311751870.228
neurogenesisGO:00220082360.222
regulation of cell cycleGO:00517261940.221
cellular component morphogenesisGO:00329893180.207
cytoskeleton organizationGO:00070103390.206
germ cell developmentGO:00072813510.196
genitalia developmentGO:00488067410.193
cellular process involved in reproduction in multicellular organismGO:00224123510.188
multi organism reproductive behaviorGO:00447053870.180
establishment of localization in cellGO:00516493180.180
establishment of organelle localizationGO:00516561230.176
rna biosynthetic processGO:00327741690.175
microtubule polymerization or depolymerizationGO:0031109220.168
cell morphogenesis involved in neuron differentiationGO:00486671110.166
protein complex subunit organizationGO:00718222800.165
centromere complex assemblyGO:003450850.165
reproductive behaviorGO:00190983870.163
cell part morphogenesisGO:00329901520.160
neuron differentiationGO:00301822170.160
post embryonic developmentGO:000979121520.156
cell projection organizationGO:00300302310.155
generation of neuronsGO:00486992350.154
cellular component movementGO:00069283880.152
aromatic compound biosynthetic processGO:00194381920.149
positive regulation of cellular processGO:00485223320.140
regulation of primary metabolic processGO:00800902920.139
transcription dna templatedGO:00063511680.137
regulation of rna biosynthetic processGO:20011411650.133
cell developmentGO:00484686960.132
regulation of transcription dna templatedGO:00063551640.129
regulation of gene expressionGO:00104683660.129
receptor mediated endocytosisGO:00068987150.128
regulation of macromolecule biosynthetic processGO:00105561890.128
transcription from rna polymerase ii promoterGO:00063661490.123
organelle localizationGO:00516401270.122
regulation of cellular macromolecule biosynthetic processGO:20001121880.119
multicellular organismal reproductive behaviorGO:00330573840.118
phosphate containing compound metabolic processGO:00067962320.117
organic substance biosynthetic processGO:19015763230.116
macromolecular complex subunit organizationGO:00439333200.112
multi multicellular organism processGO:00447063900.111
neuron projection morphogenesisGO:00488121140.111
macromolecule biosynthetic processGO:00090592500.108
regulation of rna metabolic processGO:00512521730.107
regulation of biological qualityGO:00650087410.106
single organism localizationGO:19025785180.103
regulation of nucleobase containing compound metabolic processGO:00192192220.101
regulation of mitotic cell cycleGO:0007346760.101
biosynthetic processGO:00090583230.100
response to chemicalGO:00422213560.100
catabolic processGO:00090563180.099
spindle assemblyGO:005122580.099
cellular nitrogen compound biosynthetic processGO:00442711920.099
cell migrationGO:00164773060.099
cellular biosynthetic processGO:00442493150.095
meiotic nuclear divisionGO:00071263000.093
microtubule anchoringGO:003445380.093
negative regulation of cellular processGO:00485232390.092
regulation of cellular component organizationGO:00511282480.092
agingGO:00075688120.091
determination of adult lifespanGO:00083408120.089
cellular component biogenesisGO:00440852970.089
organic substance catabolic processGO:19015752940.087
nucleic acid templated transcriptionGO:00976591690.082
meiotic cell cycle processGO:19030461700.080
cellular response to dna damage stimulusGO:0006974410.079
regulation of macromolecule metabolic processGO:00602554210.079
negative regulation of gene expressionGO:00106292170.078
negative regulation of developmental processGO:00510932270.075
macromolecule catabolic processGO:00090572020.074
axon developmentGO:00615641630.074
regulation of cell divisionGO:00513021420.073
body morphogenesisGO:00101716200.073
multicellular organismal agingGO:00102598120.073
cell motilityGO:00488703130.073
regulation of nucleic acid templated transcriptionGO:19035061650.070
cellular macromolecular complex assemblyGO:00346221840.070
fertilizationGO:0009566630.070
nervous system developmentGO:00073992530.068
cell cycle phase transitionGO:0044770190.067
regulation of cellular biosynthetic processGO:00313261890.067
protein metabolic processGO:00195384220.067
growthGO:00400075620.066
regulation of microtubule cytoskeleton organizationGO:0070507210.066
behaviorGO:00076105270.065
gene silencing by rnaGO:00310471430.065
rna metabolic processGO:00160702280.064
developmental growthGO:00485894120.064
organic cyclic compound biosynthetic processGO:19013621950.064
negative regulation of cell cycleGO:0045786530.064
positive regulation of developmental processGO:00510944080.063
negative regulation of vulval developmentGO:00400272060.061
regulation of multicellular organismal processGO:00512397260.061
regulation of meiosisGO:0040020940.061
phosphorus metabolic processGO:00067932320.060
regulation of gene expression epigeneticGO:00400291630.060
kinetochore assemblyGO:005138250.060
macromolecule localizationGO:00330367710.059
localization of cellGO:00516743130.058
positive regulation of nitrogen compound metabolic processGO:00511731340.058
cellular nitrogen compound catabolic processGO:00442701190.058
polar body extrusion after meiotic divisionsGO:0040038140.056
single fertilizationGO:0007338610.056
kinetochore organizationGO:005138370.055
regulation of meiotic cell cycleGO:00514451360.054
maintenance of locationGO:00512355800.054
ribose phosphate metabolic processGO:0019693990.053
cellular macromolecule catabolic processGO:0044265730.052
cell proliferationGO:00082831160.052
maintenance of protein locationGO:0045185150.052
multi organism behaviorGO:00517053890.051
oogenesisGO:00484772290.051
cellular component assemblyGO:00226072930.050
cell divisionGO:00513012620.050
positive regulation of nematode larval developmentGO:0061063540.050
female meiotic divisionGO:0007143170.049
positive regulation of transcription dna templatedGO:00458931020.049
organelle assemblyGO:00709252140.049
regulation of cell cycle processGO:00105641450.048
posttranscriptional gene silencing by rnaGO:00351941430.047
organonitrogen compound metabolic processGO:19015641510.046
attachment of mitotic spindle microtubules to kinetochoreGO:005131560.046
protein complex biogenesisGO:00702711860.045
regulation of developmental processGO:00507936840.045
chromosome organization involved in meiosisGO:0070192250.045
neuron projection guidanceGO:0097485820.044
macromolecular complex assemblyGO:00650031930.044
regulation of cellular ketone metabolic processGO:001056530.044
dendrite developmentGO:0016358420.044
aromatic compound catabolic processGO:00194391160.043
nucleobase containing compound biosynthetic processGO:00346541840.043
metaphase anaphase transition of cell cycleGO:0044784150.042
regulation of cellular metabolic processGO:00313233050.041
chromosome organizationGO:00512761040.041
pronuclear migrationGO:0035046510.040
purine nucleotide metabolic processGO:0006163950.040
gene silencingGO:00164581430.040
positive regulation of multicellular organismal processGO:00512404170.040
cell morphogenesis involved in differentiationGO:00009041120.039
regulation of microtubule based processGO:0032886210.039
male sex differentiationGO:0046661860.038
nucleotide metabolic processGO:00091171080.038
dna repairGO:0006281230.038
lipid storageGO:00199155650.038
cellular protein modification processGO:00064642070.038
regulation of nitrogen compound metabolic processGO:00511712220.037
regulation of transcription from rna polymerase ii promoterGO:00063571450.037
neuron developmentGO:00486661990.037
positive regulation of macromolecule biosynthetic processGO:00105571090.037
cellular catabolic processGO:00442481990.036
macromolecule modificationGO:00434122180.035
single organism catabolic processGO:00447121290.035
lipid localizationGO:00108765730.035
regulation of organelle organizationGO:00330431640.034
homeostatic processGO:0042592510.034
negative regulation of gene expression epigeneticGO:004581420.034
regulation of metabolic processGO:00192224780.033
establishment of spindle localizationGO:0051293510.033
nucleoside phosphate metabolic processGO:00067531080.033
cellular protein metabolic processGO:00442672790.033
positive regulation of post embryonic developmentGO:0048582540.032
carbohydrate derivative metabolic processGO:19011351410.032
positive regulation of cellular metabolic processGO:00313251780.031
single organism signalingGO:00447004010.031
posttranscriptional gene silencingGO:00164411430.031
dna duplex unwindingGO:003250830.031
protein localizationGO:00081042050.031
cytokinesisGO:0000910800.031
negative regulation of metabolic processGO:00098922400.031
negative regulation of nucleic acid templated transcriptionGO:1903507530.030
negative regulation of multicellular organismal processGO:00512412360.030
rna interferenceGO:00162461370.030
protein catabolic processGO:00301631620.030
endocytosisGO:00068978190.030
positive regulation of gene expressionGO:00106281120.029
multicellular organism growthGO:00352643850.029
response to oxygen containing compoundGO:1901700440.029
chemotaxisGO:00069351200.029
molting cycleGO:00423032810.028
organic cyclic compound catabolic processGO:19013611190.028
cytokinesis completion of separationGO:000710940.028
cell fate commitmentGO:00451651390.027
mitotic sister chromatid separationGO:0051306130.027
dna templated transcription elongationGO:000635410.027
regulation of growthGO:00400084090.027
purine nucleoside metabolic processGO:0042278920.027
cellular protein complex assemblyGO:00436231780.027
negative regulation of mitotic cell cycleGO:0045930420.026
nucleobase containing compound catabolic processGO:00346551140.026
regulation of vulval developmentGO:00400282480.026
small molecule metabolic processGO:00442811860.026
regulation of chromosome segregationGO:0051983200.026
negative regulation of rna biosynthetic processGO:1902679530.025
negative regulation of macromolecule metabolic processGO:00106052290.025
ubiquitin dependent protein catabolic processGO:0006511320.025
positive regulation of nucleobase containing compound metabolic processGO:00459351340.025
cellular amine metabolic processGO:0044106150.025
mitotic g2 m transition checkpointGO:004481810.024
peptidyl amino acid modificationGO:0018193580.024
heterocycle biosynthetic processGO:00181301870.024
cellular ketone metabolic processGO:0042180140.024
regulation of nuclear divisionGO:00517831150.024
regulation of mitotic metaphase anaphase transitionGO:003007150.024
cellular protein localizationGO:0034613750.024
organonitrogen compound catabolic processGO:1901565900.024
vesicle mediated transportGO:00161928520.023
meiotic cytokinesisGO:0033206150.023
modification dependent protein catabolic processGO:0019941320.023
cellular response to stressGO:00335541620.023
nucleoside monophosphate metabolic processGO:0009123460.023
regulation of response to stimulusGO:00485832430.022
regulation of nematode larval developmentGO:00610622600.022
establishment of cell polarityGO:0030010460.022
axonogenesisGO:00074091020.022
amine metabolic processGO:0009308150.022
actin filament based processGO:00300291910.022
deathGO:00162655470.022
positive regulation of multicellular organism growthGO:00400183520.022
protein complex assemblyGO:00064611860.022
negative regulation of nitrogen compound metabolic processGO:0051172630.022
spindle assembly involved in mitosisGO:009030760.022
internal peptidyl lysine acetylationGO:001839330.022
purine ribonucleoside triphosphate catabolic processGO:0009207720.022
response to organic substanceGO:00100331310.022
meiosis iGO:0007127190.021
head developmentGO:006032210.021
regulation of localizationGO:00328791940.021
negative regulation of cellular biosynthetic processGO:0031327650.021
regulation of cellular amine metabolic processGO:003323800.021
nuclear migrationGO:0007097540.021
regulation of post embryonic developmentGO:00485802600.021
dna recombinationGO:0006310190.021
negative regulation of post embryonic developmentGO:00485812080.021
positive regulation of vulval developmentGO:0040026520.021
muscle structure developmentGO:00610611910.020
regulation of locomotionGO:00400121610.020
glycosyl compound metabolic processGO:19016571000.020
axon guidanceGO:0007411820.020
positive regulation of growthGO:00459273690.020
ribonucleoside triphosphate metabolic processGO:0009199870.020
post embryonic organ developmentGO:00485693360.020
inductive cell migrationGO:00400391450.020
proteasomal protein catabolic processGO:0010498200.020
posttranscriptional regulation of gene expressionGO:00106081660.019
regulation of multicellular organism growthGO:00400143730.019
establishment of nucleus localizationGO:0040023550.019
regulation of cell differentiationGO:0045595810.019
regulation of attachment of spindle microtubules to kinetochoreGO:005198820.019
protein modification processGO:00362112070.019
regulation of cellular amino acid metabolic processGO:000652100.019
vulval developmentGO:00400253330.019
organic acid metabolic processGO:0006082470.018
protein phosphorylationGO:0006468850.018
transportGO:000681010930.018
female gamete generationGO:00072922540.018
regulation of biosynthetic processGO:00098891890.018
regulation of cell motilityGO:2000145570.018
cell deathGO:00082195470.018
carbohydrate derivative catabolic processGO:1901136820.018
organophosphate metabolic processGO:00196371250.018
regulation of mitotic sister chromatid segregationGO:0033047160.018
striated muscle cell differentiationGO:00511461580.018
positive regulation of nucleic acid templated transcriptionGO:19035081020.018
purine containing compound metabolic processGO:0072521950.017
ribonucleoside catabolic processGO:0042454770.017
regulation of cell proliferationGO:00421271050.017
dna replicationGO:0006260150.017
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.017
actomyosin structure organizationGO:00310321540.017
cuticle developmentGO:00423351000.017
negative regulation of organelle organizationGO:0010639200.017
dna conformation changeGO:0071103110.017
ribonucleoside monophosphate metabolic processGO:0009161450.017
ribonucleotide metabolic processGO:0009259990.016
regulation of cellular component movementGO:0051270620.016
purine nucleoside catabolic processGO:0006152750.016
cellular amino acid metabolic processGO:0006520150.016
protein modification by small protein conjugation or removalGO:0070647400.016
oxoacid metabolic processGO:0043436470.016
actin cytoskeleton organizationGO:00300361840.016
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.016
negative regulation of chromosome segregationGO:005198540.016
regulation of cytoskeleton organizationGO:0051493410.015
establishment of mitotic spindle orientationGO:0000132280.015
nucleobase containing small molecule metabolic processGO:00550861150.015
molting cycle collagen and cuticulin based cuticleGO:00189962810.015
neuromuscular junction developmentGO:000752820.015
cellular macromolecule localizationGO:0070727750.015
regulation of cell cycle phase transitionGO:1901987130.015
positive regulation of rna biosynthetic processGO:19026801020.015
collagen and cuticulin based cuticle developmentGO:0040002990.015
positive regulation of developmental growthGO:00486393540.015
mitotic cell cycle phase transitionGO:0044772130.015
negative regulation of cellular protein catabolic processGO:190336340.014
purine ribonucleotide metabolic processGO:0009150950.014
protein polymerizationGO:0051258260.014
nucleoside phosphate catabolic processGO:1901292770.014
dna geometric changeGO:003239230.014
programmed cell deathGO:00125015000.014
positive regulation of macromolecule metabolic processGO:00106041490.014
purine ribonucleoside catabolic processGO:0046130750.014
mitotic cell cycle checkpointGO:000709350.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.014
regulation of multicellular organismal developmentGO:20000263170.014
metaphase anaphase transition of mitotic cell cycleGO:0007091100.014
negative regulation of macromolecule biosynthetic processGO:0010558650.014
epithelial tube morphogenesisGO:006056210.013
positive regulation of cellular biosynthetic processGO:00313281090.013
nucleoside metabolic processGO:0009116990.013
positive regulation of chromosome organizationGO:200125220.013
positive regulation of stem cell differentiationGO:200073810.013
meiosis iiGO:0007135160.013
taxisGO:00423301280.013
microtubule based movementGO:0007018330.013
tube developmentGO:00352951260.013
dna packagingGO:000632370.013
g1 s transition of mitotic cell cycleGO:000008220.013
response to external stimulusGO:00096052890.013
positive regulation of rna metabolic processGO:00512541030.013
cellular component assembly involved in morphogenesisGO:00109271830.013
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243540.013
defense responseGO:00069522960.012
spindle localizationGO:0051653510.012
positive regulation of cell cycleGO:0045787550.012
protein dna complex assemblyGO:006500470.012
cytoskeleton dependent cytokinesisGO:0061640350.012
atp metabolic processGO:0046034420.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.012
regulation of protein localizationGO:0032880500.012
positive regulation of chromosome segregationGO:005198410.012
glycosyl compound catabolic processGO:1901658790.012
signal transductionGO:00071653170.012
chromatin assemblyGO:003149710.012
proteolysisGO:0006508610.012
negative regulation of nematode larval developmentGO:00610642080.012
positive regulation of neurogenesisGO:005076940.012
peptidyl lysine acetylationGO:001839430.012
protein dna complex subunit organizationGO:007182470.011
regulation of mitosisGO:0007088180.011
establishment of mitotic spindle localizationGO:0040001410.011
purine nucleoside triphosphate catabolic processGO:0009146720.011
regulation of developmental growthGO:00486383890.011
regulation of apoptotic signaling pathwayGO:200123310.011
regulation of mitotic spindle organizationGO:006023630.011
centrosome cycleGO:0007098130.011
spindle checkpointGO:003157740.011
cellular response to organic substanceGO:00713101190.011
nucleoside triphosphate metabolic processGO:0009141870.011
positive regulation of intracellular transportGO:003238820.011
phosphorylationGO:00163101160.011
ribonucleoside triphosphate catabolic processGO:0009203720.011
negative regulation of mitotic sister chromatid segregationGO:003304840.011
regulation of epithelial cell differentiationGO:003085640.011
negative regulation of transcription dna templatedGO:0045892530.011
nucleic acid phosphodiester bond hydrolysisGO:0090305280.011
purine ribonucleoside triphosphate metabolic processGO:0009205870.011
microtubule depolymerizationGO:0007019100.011
protein localization to organelleGO:0033365370.011
purine ribonucleoside monophosphate metabolic processGO:0009167430.010
organ morphogenesisGO:0009887670.010
nucleus localizationGO:0051647550.010
chromatin remodelingGO:000633820.010
mitotic spindle stabilizationGO:004314820.010
positive regulation of biosynthetic processGO:00098911090.010
regulation of nucleocytoplasmic transportGO:004682230.010
signalingGO:00230524010.010
regulation of cellular catabolic processGO:0031329510.010
purine nucleoside triphosphate metabolic processGO:0009144870.010
negative regulation of nucleobase containing compound metabolic processGO:0045934630.010

him-10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.033
cancerDOID:16200.022
disease of anatomical entityDOID:700.021
organ system cancerDOID:005068600.019
gastrointestinal system cancerDOID:311900.017
intestinal cancerDOID:1015500.015
large intestine cancerDOID:567200.015