Caenorhabditis elegans

61 known processes

pak-1 (CELE_C09B8.7)

Protein PAK-1

pak-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.619
response to endoplasmic reticulum stressGO:0034976710.537
embryo developmentGO:000979030520.359
locomotionGO:004001116340.313
regulation of phosphorus metabolic processGO:0051174810.300
Human Yeast Worm
receptor mediated endocytosisGO:00068987150.272
endocytosisGO:00068978190.271
establishment of localizationGO:005123411710.263
Yeast
regulation of phosphate metabolic processGO:0019220810.228
Human Yeast Worm
body morphogenesisGO:00101716200.212
transportGO:000681010930.197
Yeast
signal transductionGO:00071653170.184
Human Yeast Worm
cell cycleGO:00070495260.172
Yeast
behaviorGO:00076105270.166
neuron projection developmentGO:00311751870.164
Mouse Rat Worm
regulation of localizationGO:00328791940.161
regulation of multicellular organismal processGO:00512397260.159
Rat
organelle organizationGO:00069967830.153
Human Yeast Rat
positive regulation of signalingGO:0023056660.150
Human Yeast Worm
vesicle mediated transportGO:00161928520.145
positive regulation of developmental processGO:00510944080.143
Rat
regulation of purine nucleotide catabolic processGO:0033121350.141
regulation of metabolic processGO:00192224780.141
Human Yeast Rat Worm
positive regulation of cellular processGO:00485223320.138
Human Yeast Rat Worm
single organism reproductive processGO:004470211960.135
ovipositionGO:00189913640.134
phosphate containing compound metabolic processGO:00067962320.134
single organism localizationGO:19025785180.123
Yeast Mouse
regulation of signal transductionGO:00099661350.122
Human Yeast Worm
cellular response to unfolded proteinGO:0034620710.121
positive regulation of multicellular organismal processGO:00512404170.119
Rat
regulation of developmental processGO:00507936840.117
Rat
signalingGO:00230524010.117
Human Yeast Worm
regulation of nucleoside metabolic processGO:0009118370.116
cell developmentGO:00484686960.116
Mouse Rat Worm
post embryonic developmentGO:000979121520.114
cell cycle processGO:00224024820.114
Yeast
positive regulation of metabolic processGO:00098931870.110
Human Yeast Rat Worm
phosphorus metabolic processGO:00067932320.109
cell migrationGO:00164773060.108
positive regulation of developmental growthGO:00486393540.107
multi organism behaviorGO:00517053890.103
aromatic compound biosynthetic processGO:00194381920.101
Rat
organelle fissionGO:00482853630.101
Yeast
cell morphogenesis involved in differentiationGO:00009041120.099
Mouse Rat Worm
pattern specification processGO:0007389590.097
positive regulation of nucleic acid templated transcriptionGO:19035081020.095
regulation of growthGO:00400084090.091
positive regulation of nitrogen compound metabolic processGO:00511731340.091
Rat
cell motilityGO:00488703130.091
single organism signalingGO:00447004010.090
Human Yeast Worm
cellular localizationGO:00516413600.090
Mouse
macromolecule localizationGO:00330367710.089
Yeast Mouse
regulation of nitrogen compound metabolic processGO:00511712220.087
Rat
cellular process involved in reproduction in multicellular organismGO:00224123510.084
regulation of macromolecule metabolic processGO:00602554210.082
Human Yeast Rat Worm
multi organism reproductive behaviorGO:00447053870.080
localization of cellGO:00516743130.078
agingGO:00075688120.078
Worm
ras protein signal transductionGO:0007265310.077
single organism behaviorGO:0044708830.075
multicellular organism reproductionGO:00325048190.074
determination of adult lifespanGO:00083408120.074
Worm
phosphorylationGO:00163101160.074
multicellular organismal reproductive processGO:00486098150.073
regulation of developmental growthGO:00486383890.070
small gtpase mediated signal transductionGO:0007264320.070
reproductive behaviorGO:00190983870.069
neuron differentiationGO:00301822170.069
Mouse Rat Worm
mitotic cell cycle processGO:19030471940.068
Yeast
lipid storageGO:00199155650.067
cell projection organizationGO:00300302310.066
Mouse Rat Worm
single organism organelle organizationGO:19025895010.066
Human Yeast Rat
maintenance of locationGO:00512355800.065
generation of neuronsGO:00486992350.065
Mouse Rat Worm
developmental growthGO:00485894120.065
development of primary sexual characteristicsGO:00451378400.065
regulation of molecular functionGO:0065009890.063
Human Yeast Worm
germ cell developmentGO:00072813510.062
regulation of multicellular organismal developmentGO:20000263170.062
Rat
multi multicellular organism processGO:00447063900.062
gonad developmentGO:00084068400.061
establishment of localization in cellGO:00516493180.061
intracellular signal transductionGO:0035556960.061
Human Yeast Worm
genitalia developmentGO:00488067410.061
regulation of biological qualityGO:00650087410.061
Human
meiotic cell cycleGO:00513213350.061
positive regulation of multicellular organism growthGO:00400183520.060
cell surface receptor signaling pathwayGO:00071661490.060
Human Yeast
positive regulation of phosphate metabolic processGO:0045937560.059
Human Yeast Worm
protein localizationGO:00081042050.059
Mouse
microtubule based processGO:00070171820.059
regulation of multicellular organism growthGO:00400143730.059
positive regulation of phosphorus metabolic processGO:0010562560.058
Human Yeast Worm
lipid localizationGO:00108765730.058
Yeast
positive regulation of growthGO:00459273690.057
positive regulation of cell communicationGO:0010647690.057
Human Yeast Worm
sex differentiationGO:00075489090.057
oogenesisGO:00484772290.055
multicellular organismal agingGO:00102598120.055
Worm
response to chemicalGO:00422213560.054
Yeast Rat Worm
macromolecule catabolic processGO:00090572020.052
regulation of cell communicationGO:00106461760.052
Human Yeast Worm
regulation of cellular metabolic processGO:00313233050.052
Human Yeast Rat Worm
positive regulation of response to stimulusGO:0048584550.050
Human Yeast Worm
regulation of cellular macromolecule biosynthetic processGO:20001121880.050
Rat
multi organism reproductive processGO:00447038670.049
Yeast
cellular component movementGO:00069283880.049
cellular component biogenesisGO:00440852970.049
regulation of primary metabolic processGO:00800902920.048
Human Yeast Rat Worm
growthGO:00400075620.048
Yeast
nervous system developmentGO:00073992530.047
Mouse Rat Worm
catabolic processGO:00090563180.047
organic substance catabolic processGO:19015752940.047
gamete generationGO:00072764610.047
regulation of behaviorGO:0050795970.047
protein complex subunit organizationGO:00718222800.046
Human
sexual reproductionGO:00199535460.046
Yeast
regulation of catalytic activityGO:0050790780.045
Human Yeast Worm
positive regulation of molecular functionGO:0044093610.044
Human Yeast Worm
rna biosynthetic processGO:00327741690.044
purine nucleotide metabolic processGO:0006163950.044
positive regulation of gtpase activityGO:0043547280.043
biosynthetic processGO:00090583230.043
Rat
positive regulation of nucleoside metabolic processGO:0045979280.043
cell deathGO:00082195470.041
Human Yeast Rat
female gamete generationGO:00072922540.041
neurogenesisGO:00220082360.041
Mouse Rat Worm
cellular response to topologically incorrect proteinGO:0035967760.040
embryonic morphogenesisGO:00485981520.040
nucleobase containing compound biosynthetic processGO:00346541840.040
Rat
transcription dna templatedGO:00063511680.040
macromolecular complex subunit organizationGO:00439333200.039
Human Yeast
single organism catabolic processGO:00447121290.039
regulation of cellular component organizationGO:00511282480.039
Human Yeast Rat
establishment of organelle localizationGO:00516561230.039
regulation of catabolic processGO:0009894570.039
regulation of signalingGO:00230511720.038
Human Yeast Worm
positive regulation of catalytic activityGO:0043085590.038
Human Yeast Worm
reproductive system developmentGO:00614588500.038
actin cytoskeleton organizationGO:00300361840.037
Human Rat
purine ribonucleoside triphosphate metabolic processGO:0009205870.037
neuron developmentGO:00486661990.037
Mouse Rat Worm
regulation of cell morphogenesisGO:0022604400.035
Rat
cellular macromolecule biosynthetic processGO:00346452470.035
Rat
hermaphrodite genitalia developmentGO:00400357340.035
membrane organizationGO:00610241350.035
Mouse
positive regulation of macromolecule metabolic processGO:00106041490.034
Human Yeast Rat Worm
organ developmentGO:004851311020.034
stress activated protein kinase signaling cascadeGO:0031098100.034
Human Worm
cytoskeleton organizationGO:00070103390.034
Human Rat
intraspecies interaction between organismsGO:005170330.033
multicellular organism growthGO:00352643850.033
cell projection morphogenesisGO:00488581480.033
Mouse Rat Worm
meiotic nuclear divisionGO:00071263000.032
molting cycleGO:00423032810.032
regulation of transcription from rna polymerase ii promoterGO:00063571450.032
multicellular organismal reproductive behaviorGO:00330573840.032
regulation of biosynthetic processGO:00098891890.032
Rat
response to unfolded proteinGO:0006986710.032
regulation of cellular protein metabolic processGO:0032268750.031
Human Yeast Worm
regulation of nucleotide metabolic processGO:0006140370.031
tube developmentGO:00352951260.031
Human
regulation of cell morphogenesis involved in differentiationGO:0010769290.031
Rat
cellular component morphogenesisGO:00329893180.030
Mouse Rat Worm
nuclear migrationGO:0007097540.030
response to topologically incorrect proteinGO:0035966820.030
positive regulation of signal transductionGO:0009967400.030
Human Yeast Worm
deathGO:00162655470.029
Human Yeast Rat
post embryonic organ developmentGO:00485693360.029
regulation of neuron differentiationGO:0045664400.029
Rat
positive regulation of cellular catabolic processGO:0031331350.029
positive regulation of cellular metabolic processGO:00313251780.029
Human Yeast Rat Worm
organophosphate catabolic processGO:0046434810.029
cellular catabolic processGO:00442481990.029
inductive cell migrationGO:00400391450.028
embryonic pattern specificationGO:0009880210.028
macromolecular complex assemblyGO:00650031930.027
Human Yeast
cellular response to stressGO:00335541620.027
Human Yeast Worm
vulval developmentGO:00400253330.027
positive regulation of gtp catabolic processGO:0033126280.026
regulation of nucleic acid templated transcriptionGO:19035061650.026
er nucleus signaling pathwayGO:0006984660.026
regulation of response to stimulusGO:00485832430.026
Human Yeast Worm
establishment of mitotic spindle orientationGO:0000132280.026
regulation of gtp catabolic processGO:0033124320.025
negative regulation of metabolic processGO:00098922400.025
Human Yeast
tube morphogenesisGO:0035239790.025
Human
cell morphogenesisGO:00009021630.025
Mouse Rat Worm
regulation of vesicle mediated transportGO:0060627270.025
positive regulation of jnk cascadeGO:004633030.025
Human Worm
single organism transportGO:00447654470.025
Yeast
establishment of nucleus localizationGO:0040023550.024
developmental process involved in reproductionGO:000300611650.024
purine nucleoside metabolic processGO:0042278920.023
embryonic body morphogenesisGO:0010172490.023
positive regulation of catabolic processGO:0009896380.023
positive regulation of phosphorylationGO:0042327270.023
Human Yeast Worm
positive regulation of purine nucleotide catabolic processGO:0033123280.023
meiotic cell cycle processGO:19030461700.023
apoptotic processGO:00069154780.023
Human Yeast Rat
macromolecule biosynthetic processGO:00090592500.023
Rat
positive regulation of transcription dna templatedGO:00458931020.023
response to organic substanceGO:00100331310.022
Yeast Rat
chromosome segregationGO:00070591800.022
cytokinesisGO:0000910800.022
Yeast
programmed cell deathGO:00125015000.022
Human Yeast Rat
neuron recognitionGO:0008038830.022
positive regulation of intracellular signal transductionGO:1902533240.022
Human Yeast Worm
positive regulation of stress activated mapk cascadeGO:003287430.022
Human Worm
purine containing compound metabolic processGO:0072521950.021
phagocytosisGO:00069091150.021
reproductive structure developmentGO:00486088500.021
organic substance transportGO:00717021130.021
Yeast
amine metabolic processGO:0009308150.021
negative regulation of biological processGO:00485195670.021
Human Yeast
positive regulation of gene expressionGO:00106281120.021
neuron projection morphogenesisGO:00488121140.020
Mouse Rat Worm
regulation of rna biosynthetic processGO:20011411650.020
regulation of small gtpase mediated signal transductionGO:0051056410.020
response to woundingGO:000961140.020
Human
protein catabolic processGO:00301631620.020
cellular component assemblyGO:00226072930.020
nucleus localizationGO:0051647550.020
digestive tract morphogenesisGO:0048546760.020
response to external stimulusGO:00096052890.020
Worm
organic cyclic compound catabolic processGO:19013611190.020
dauer larval developmentGO:0040024920.020
cellular biosynthetic processGO:00442493150.020
Rat
positive regulation of cellular biosynthetic processGO:00313281090.019
Rat
positive regulation of purine nucleotide metabolic processGO:1900544280.019
regulation of ras gtpase activityGO:0032318210.019
molting cycle collagen and cuticulin based cuticleGO:00189962810.019
cellular response to chemical stimulusGO:00708871290.019
Yeast Rat
negative regulation of gene expressionGO:00106292170.019
Human Yeast
protein modification processGO:00362112070.019
regionalizationGO:0003002310.019
guanosine containing compound metabolic processGO:1901068490.019
actin filament based processGO:00300291910.018
Human Rat
purine ribonucleotide catabolic processGO:0009154750.018
organophosphate metabolic processGO:00196371250.018
positive regulation of proteasomal protein catabolic processGO:190180010.018
protein metabolic processGO:00195384220.018
regulation of multi organism processGO:0043900690.018
dendrite developmentGO:0016358420.018
Mouse Rat
cellular macromolecular complex assemblyGO:00346221840.018
Human Yeast
positive regulation of cell projection organizationGO:003134640.018
Rat
cellular amine metabolic processGO:0044106150.018
ribonucleoside triphosphate catabolic processGO:0009203720.018
organonitrogen compound metabolic processGO:19015641510.018
cell divisionGO:00513012620.018
Yeast
cell part morphogenesisGO:00329901520.018
Mouse Rat Worm
macromolecule modificationGO:00434122180.018
rna metabolic processGO:00160702280.018
innate immune responseGO:00450871900.018
regulation of endocytosisGO:0030100250.017
meiotic chromosome segregationGO:00451321390.017
regulation of anatomical structure morphogenesisGO:0022603510.017
Rat
regulation of organelle organizationGO:00330431640.017
Human Yeast Rat
regulation of hydrolase activityGO:0051336450.017
Human
nucleic acid metabolic processGO:00903042990.017
Rat
nucleoside metabolic processGO:0009116990.017
gastrulationGO:0007369580.017
head developmentGO:006032210.017
organelle localizationGO:00516401270.017
defense responseGO:00069522960.017
regulation of nematode larval developmentGO:00610622600.017
cell proliferationGO:00082831160.017
Human
endoplasmic reticulum unfolded protein responseGO:0030968660.017
protein phosphorylationGO:0006468850.017
protein complex biogenesisGO:00702711860.017
Human
digestive tract developmentGO:00485651220.016
regulation of purine nucleotide metabolic processGO:1900542370.016
regulation of transportGO:0051049910.016
regulation of cellular catabolic processGO:0031329510.016
negative regulation of multicellular organismal processGO:00512412360.016
digestive system developmentGO:00551231220.016
axonal fasciculationGO:0007413790.016
positive regulation of nucleotide catabolic processGO:0030813280.016
gene expressionGO:00104674120.016
Human Yeast
nematode male tail tip morphogenesisGO:0045138770.016
oxoacid metabolic processGO:0043436470.016
purine nucleoside triphosphate metabolic processGO:0009144870.016
regulation of gene expressionGO:00104683660.016
Human Yeast
nucleoside triphosphate metabolic processGO:0009141870.016
cellular response to organic substanceGO:00713101190.016
Yeast Rat
cell recognitionGO:0008037850.015
posttranscriptional regulation of gene expressionGO:00106081660.015
regulation of protein metabolic processGO:0051246810.015
Human Yeast Worm
purine nucleotide catabolic processGO:0006195750.015
transcription from rna polymerase ii promoterGO:00063661490.015
organic substance biosynthetic processGO:19015763230.015
Rat
response to abiotic stimulusGO:00096281520.015
Yeast Rat
regulation of nucleotide catabolic processGO:0030811350.015
heterocycle biosynthetic processGO:00181301870.015
Rat
regulation of cell cycle processGO:00105641450.015
Yeast
regulation of cellular biosynthetic processGO:00313261890.015
Rat
positive regulation of rna biosynthetic processGO:19026801020.015
ribonucleoside triphosphate metabolic processGO:0009199870.015
oocyte axis specificationGO:000730920.014
purine containing compound catabolic processGO:0072523750.014
posttranscriptional gene silencingGO:00164411430.014
regulation of anatomical structure sizeGO:0090066460.014
Human
cellular macromolecule catabolic processGO:0044265730.014
rna localizationGO:000640330.014
regulation of cell motilityGO:2000145570.014
regulation of intracellular signal transductionGO:1902531770.014
Human Yeast Worm
regulation of cell differentiationGO:0045595810.014
Rat
spindle organizationGO:0007051920.014
positive regulation of cell morphogenesis involved in differentiationGO:001077040.014
Rat
asymmetric protein localizationGO:0008105350.014
small molecule metabolic processGO:00442811860.014
positive regulation of cellular protein catabolic processGO:190336430.014
memoryGO:000761330.014
pole plasm assemblyGO:000731520.014
regulation of meiotic cell cycleGO:00514451360.014
regulation of transcription dna templatedGO:00063551640.013
posttranscriptional gene silencing by rnaGO:00351941430.013
mapk cascadeGO:0000165310.013
Human Yeast Worm
ribonucleoside catabolic processGO:0042454770.013
axonogenesisGO:00074091020.013
Mouse Worm
secretion by cellGO:00329401380.013
organonitrogen compound catabolic processGO:1901565900.013
response to other organismGO:00517071010.013
aromatic compound catabolic processGO:00194391160.013
organic cyclic compound biosynthetic processGO:19013621950.013
Rat
response to biotic stimulusGO:00096071010.013
organ morphogenesisGO:0009887670.013
stress activated mapk cascadeGO:0051403100.013
Human Worm
regulation of cell migrationGO:0030334550.013
regulation of apoptotic signaling pathwayGO:200123310.013
Human
positive regulation of proteolysis involved in cellular protein catabolic processGO:190305210.013
rna interferenceGO:00162461370.013
regulation of locomotionGO:00400121610.012
single fertilizationGO:0007338610.012
positive regulation of cellular component organizationGO:0051130340.012
Human Rat
regulation of nucleobase containing compound metabolic processGO:00192192220.012
Rat
signal transduction by phosphorylationGO:0023014310.012
Human Yeast Worm
regulation of gtpase activityGO:0043087300.012
negative regulation of signal transductionGO:0009968600.012
protein complex assemblyGO:00064611860.012
Human
anatomical structure formation involved in morphogenesisGO:00486462500.012
nucleobase containing small molecule metabolic processGO:00550861150.012
ribonucleotide catabolic processGO:0009261750.012
chemotaxisGO:00069351200.012
Worm
response to bacteriumGO:0009617860.012
peptidyl tyrosine phosphorylationGO:001810820.012
Human
positive regulation of rna metabolic processGO:00512541030.012
jnk cascadeGO:000725480.012
Human Worm
glycosyl compound metabolic processGO:19016571000.012
nucleotide metabolic processGO:00091171080.012
ribonucleoprotein complex assemblyGO:002261840.012
Yeast
positive regulation of protein kinase activityGO:0045860180.012
Human Yeast Worm
cellular protein metabolic processGO:00442672790.012
epithelial tube morphogenesisGO:006056210.012
Human
nucleoside triphosphate catabolic processGO:0009143720.012
regulation of transferase activityGO:0051338310.012
Human Yeast Worm
system processGO:00030081360.012
positive regulation of transportGO:0051050320.012
neuromuscular junction developmentGO:000752820.011
Mouse
cellular amino acid metabolic processGO:0006520150.011
regulation of stem cell differentiationGO:200073610.011
nucleic acid templated transcriptionGO:00976591690.011
response to endogenous stimulusGO:0009719330.011
Rat
regulation of mapk cascadeGO:0043408230.011
Human Yeast Worm
gene silencing by rnaGO:00310471430.011
regulation of cell cycleGO:00517261940.011
Yeast
germline cell cycle switching mitotic to meiotic cell cycleGO:0051729350.011
positive regulation of cell migrationGO:003033530.011
regulation of phagocytosis engulfmentGO:0060099170.011
g1 s transition of mitotic cell cycleGO:000008220.011
dorsal ventral axon guidanceGO:0033563190.011
heterocycle catabolic processGO:00467001190.011
cell fate commitmentGO:00451651390.011
protein oligomerizationGO:005125940.011
enzyme linked receptor protein signaling pathwayGO:0007167500.010
male anatomical structure morphogenesisGO:0090598780.010
negative regulation of vulval developmentGO:00400272060.010
positive regulation of cell cycleGO:0045787550.010
cellular nitrogen compound biosynthetic processGO:00442711920.010
Rat
carbohydrate derivative catabolic processGO:1901136820.010
negative regulation of response to stimulusGO:0048585730.010
taxisGO:00423301280.010
Worm
regulation of phagocytosisGO:0050764180.010
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361820.010
gtp catabolic processGO:0006184460.010
spindle localizationGO:0051653510.010
regulation of lipid metabolic processGO:001921640.010
regulation of cell deathGO:0010941650.010
Human Yeast Rat
positive regulation of kinase activityGO:0033674190.010
Human Yeast Worm
regulation of post embryonic developmentGO:00485802600.010
nucleoside phosphate catabolic processGO:1901292770.010

pak-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014