Caenorhabditis elegans

89 known processes

unc-15 (CELE_F07A5.7)

Protein UNC-15

unc-15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sarcomere organizationGO:0045214101.000
muscle tissue developmentGO:006053710.833
skeletal muscle thin filament assemblyGO:003024030.787
cellular component morphogenesisGO:00329893180.776
striated muscle cell developmentGO:00550021570.718
organelle assemblyGO:00709252140.705
body morphogenesisGO:00101716200.704
cytoskeleton organizationGO:00070103390.679
embryonic body morphogenesisGO:0010172490.672
cellular component assemblyGO:00226072930.615
embryo developmentGO:000979030520.610
skeletal muscle organ developmentGO:006053830.590
actin filament based processGO:00300291910.580
cellular component assembly involved in morphogenesisGO:00109271830.574
locomotionGO:004001116340.554
muscle cell developmentGO:00550011580.537
post embryonic developmentGO:000979121520.519
actomyosin structure organizationGO:00310321540.468
anatomical structure formation involved in morphogenesisGO:00486462500.467
organelle organizationGO:00069967830.442
establishment of localizationGO:005123411710.420
female gamete generationGO:00072922540.416
skeletal myofibril assemblyGO:001486670.414
actin cytoskeleton organizationGO:00300361840.413
single organism organelle organizationGO:19025895010.409
cellular component biogenesisGO:00440852970.400
gamete generationGO:00072764610.389
embryo development ending in birth or egg hatchingGO:000979229920.388
myofibril assemblyGO:00302391540.352
muscle organ developmentGO:0007517260.345
regulation of atp catabolic processGO:190328930.328
embryonic morphogenesisGO:00485981520.324
nucleobase containing compound metabolic processGO:00061394060.319
muscle cell differentiationGO:00426921710.311
transportGO:000681010930.299
sexual reproductionGO:00199535460.294
cellular protein complex assemblyGO:00436231780.274
protein complex subunit organizationGO:00718222800.274
inductive cell migrationGO:00400391450.272
cellular macromolecular complex assemblyGO:00346221840.271
muscle structure developmentGO:00610611910.269
single organism localizationGO:19025785180.253
muscle contractionGO:0006936430.253
nucleoside triphosphate catabolic processGO:0009143720.235
myosin filament assemblyGO:00310341380.225
protein complex biogenesisGO:00702711860.219
ribonucleotide catabolic processGO:0009261750.217
endocytosisGO:00068978190.203
ovipositionGO:00189913640.201
multicellular organism reproductionGO:00325048190.200
nucleoside catabolic processGO:0009164780.198
germ cell developmentGO:00072813510.198
cell developmentGO:00484686960.193
vesicle mediated transportGO:00161928520.190
receptor mediated endocytosisGO:00068987150.190
regulation of cytoskeleton organizationGO:0051493410.187
single organism reproductive processGO:004470211960.184
ovulationGO:0030728330.182
tissue developmentGO:00098881120.178
Fly
striated muscle cell differentiationGO:00511461580.173
cellular component movementGO:00069283880.169
negative regulation of biological processGO:00485195670.167
nucleic acid metabolic processGO:00903042990.165
macromolecular complex subunit organizationGO:00439333200.161
purine ribonucleoside triphosphate catabolic processGO:0009207720.158
regulation of multicellular organismal processGO:00512397260.157
meiotic nuclear divisionGO:00071263000.152
purine ribonucleoside triphosphate metabolic processGO:0009205870.149
cellular process involved in reproduction in multicellular organismGO:00224123510.148
signalingGO:00230524010.144
regulation of metabolic processGO:00192224780.143
ribonucleotide metabolic processGO:0009259990.139
cell cycle processGO:00224024820.138
muscle system processGO:0003012430.137
protein complex assemblyGO:00064611860.135
striated muscle myosin thick filament assemblyGO:00716881380.133
multicellular organismal agingGO:00102598120.133
regulation of primary metabolic processGO:00800902920.132
regulation of growthGO:00400084090.131
cell motilityGO:00488703130.125
cellular homeostasisGO:0019725220.121
actin filament organizationGO:0007015210.121
ribonucleoside triphosphate catabolic processGO:0009203720.120
multi organism reproductive processGO:00447038670.117
regulation of nitrogen compound metabolic processGO:00511712220.115
cellular nitrogen compound biosynthetic processGO:00442711920.113
molting cycleGO:00423032810.112
regulation of actin filament based processGO:0032970220.110
meiotic cell cycleGO:00513213350.110
purine ribonucleoside catabolic processGO:0046130750.108
tube morphogenesisGO:0035239790.107
mitotic cell cycle processGO:19030471940.104
regulation of developmental growthGO:00486383890.104
nucleotide catabolic processGO:0009166770.104
growthGO:00400075620.103
protein metabolic processGO:00195384220.102
nucleoside phosphate catabolic processGO:1901292770.101
organophosphate catabolic processGO:0046434810.100
neuron developmentGO:00486661990.099
determination of adult lifespanGO:00083408120.098
single organism transportGO:00447654470.096
positive regulation of multicellular organism growthGO:00400183520.093
regulation of cellular metabolic processGO:00313233050.093
signal transductionGO:00071653170.092
cell projection organizationGO:00300302310.091
spicule insertionGO:003460920.091
biosynthetic processGO:00090583230.091
negative regulation of metabolic processGO:00098922400.090
regulation of cellular macromolecule biosynthetic processGO:20001121880.089
regulation of rna biosynthetic processGO:20011411650.089
positive regulation of multicellular organismal processGO:00512404170.088
oogenesisGO:00484772290.088
cytokinesisGO:0000910800.087
nucleoside phosphate metabolic processGO:00067531080.083
regulation of catalytic activityGO:0050790780.083
regulation of nucleoside metabolic processGO:0009118370.081
cellular biosynthetic processGO:00442493150.081
macromolecule biosynthetic processGO:00090592500.081
organic cyclic compound catabolic processGO:19013611190.080
regulation of biological qualityGO:00650087410.079
behaviorGO:00076105270.079
aromatic compound catabolic processGO:00194391160.078
single organism signalingGO:00447004010.077
multi multicellular organism processGO:00447063900.076
agingGO:00075688120.075
macromolecule catabolic processGO:00090572020.075
multi organism behaviorGO:00517053890.075
purine containing compound catabolic processGO:0072523750.074
reproductive structure developmentGO:00486088500.074
purine nucleoside triphosphate catabolic processGO:0009146720.073
purine nucleotide metabolic processGO:0006163950.073
developmental growthGO:00485894120.073
purine nucleoside catabolic processGO:0006152750.072
posttranscriptional regulation of gene expressionGO:00106081660.072
ribose phosphate metabolic processGO:0019693990.072
mesoderm developmentGO:0007498270.071
Fly
organic substance catabolic processGO:19015752940.071
striated muscle contractionGO:0006941170.071
macromolecule localizationGO:00330367710.071
homeostatic processGO:0042592510.071
ribonucleoside catabolic processGO:0042454770.070
regulation of gene expressionGO:00104683660.070
multicellular organism growthGO:00352643850.069
bmp signaling pathwayGO:003050930.069
myosin filament organizationGO:00310331380.068
organ developmentGO:004851311020.067
apical junction assemblyGO:004329710.067
regulation of cellular biosynthetic processGO:00313261890.066
positive regulation of growthGO:00459273690.066
purine nucleotide catabolic processGO:0006195750.066
regulation of developmental processGO:00507936840.065
muscle organ morphogenesisGO:004864440.065
carbohydrate derivative catabolic processGO:1901136820.064
negative regulation of macromolecule metabolic processGO:00106052290.064
reproductive behaviorGO:00190983870.063
heterocycle catabolic processGO:00467001190.063
macromolecular complex assemblyGO:00650031930.062
carbohydrate derivative metabolic processGO:19011351410.062
positive regulation of developmental growthGO:00486393540.059
regulation of macromolecule metabolic processGO:00602554210.059
multicellular organismal reproductive processGO:00486098150.059
multicellular organismal reproductive behaviorGO:00330573840.058
maintenance of locationGO:00512355800.058
regulation of atpase activityGO:004346230.057
ribonucleoside triphosphate metabolic processGO:0009199870.057
collagen and cuticulin based cuticle developmentGO:0040002990.057
cytoskeleton dependent cytokinesisGO:0061640350.056
gene silencingGO:00164581430.056
catabolic processGO:00090563180.055
atp metabolic processGO:0046034420.055
genitalia developmentGO:00488067410.055
regulation of biosynthetic processGO:00098891890.053
nucleoside metabolic processGO:0009116990.053
lipid storageGO:00199155650.053
regulation of nucleobase containing compound metabolic processGO:00192192220.053
negative regulation of cellular processGO:00485232390.052
regulation of cellular component sizeGO:0032535400.052
rna metabolic processGO:00160702280.052
pharyngeal pumpingGO:0043050580.051
regulation of system processGO:0044057270.051
cellular nitrogen compound catabolic processGO:00442701190.050
somatic muscle developmentGO:000752510.050
cellular catabolic processGO:00442481990.049
gonad developmentGO:00084068400.049
organonitrogen compound catabolic processGO:1901565900.048
positive regulation of developmental processGO:00510944080.048
system processGO:00030081360.048
regulation of molecular functionGO:0065009890.047
neuron recognitionGO:0008038830.047
regulation of muscle system processGO:0090257200.047
organic substance biosynthetic processGO:19015763230.046
nucleoside triphosphate metabolic processGO:0009141870.046
neuron projection developmentGO:00311751870.046
nucleotide metabolic processGO:00091171080.046
purine ribonucleoside monophosphate catabolic processGO:0009169280.046
regulation of multicellular organism growthGO:00400143730.045
purine ribonucleoside metabolic processGO:0046128920.045
cell migrationGO:00164773060.045
purine nucleoside monophosphate catabolic processGO:0009128280.045
multi organism reproductive behaviorGO:00447053870.045
muscle fiber developmentGO:004874720.044
nucleoside monophosphate metabolic processGO:0009123460.043
atp catabolic processGO:0006200270.043
establishment or maintenance of cell polarityGO:0007163630.043
regulation of purine nucleotide catabolic processGO:0033121350.042
sex differentiationGO:00075489090.041
small gtpase mediated signal transductionGO:0007264320.041
negative regulation of nucleobase containing compound metabolic processGO:0045934630.041
lipid localizationGO:00108765730.041
regulation of cellular catabolic processGO:0031329510.041
phagocytosisGO:00069091150.040
establishment of localization in cellGO:00516493180.039
regulation of purine nucleotide metabolic processGO:1900542370.039
regulation of cell communicationGO:00106461760.039
negative regulation of gene expression epigeneticGO:004581420.038
cell deathGO:00082195470.038
purine nucleoside metabolic processGO:0042278920.037
reproductive system developmentGO:00614588500.037
localization of cellGO:00516743130.037
cuticle developmentGO:00423351000.036
gene expressionGO:00104674120.035
purine nucleoside monophosphate metabolic processGO:0009126430.035
neurogenesisGO:00220082360.035
regulation of nucleic acid templated transcriptionGO:19035061650.035
regulation of locomotionGO:00400121610.035
tube developmentGO:00352951260.034
purine nucleoside triphosphate metabolic processGO:0009144870.034
purine containing compound metabolic processGO:0072521950.034
establishment of cell polarityGO:0030010460.034
multicellular organismal movementGO:005087920.033
intracellular signal transductionGO:0035556960.033
protein catabolic processGO:00301631620.033
regulation of ras protein signal transductionGO:0046578410.033
meiotic cell cycle processGO:19030461700.033
response to chemicalGO:00422213560.032
rna biosynthetic processGO:00327741690.032
organophosphate metabolic processGO:00196371250.032
transcription dna templatedGO:00063511680.032
cell part morphogenesisGO:00329901520.032
nucleobase containing compound catabolic processGO:00346551140.032
regulation of multicellular organismal developmentGO:20000263170.031
epithelial tube morphogenesisGO:006056210.031
generation of neuronsGO:00486992350.031
purine ribonucleotide catabolic processGO:0009154750.031
directional locomotionGO:0033058140.031
eating behaviorGO:0042755590.030
positive regulation of ras gtpase activityGO:0032320190.030
regulation of gtpase activityGO:0043087300.030
developmental process involved in reproductionGO:000300611650.029
nucleobase containing compound biosynthetic processGO:00346541840.029
regulation of transcription dna templatedGO:00063551640.029
glycosyl compound metabolic processGO:19016571000.028
glycosyl compound catabolic processGO:1901658790.028
regulation of hydrolase activityGO:0051336450.028
actin filament based movementGO:003004840.028
purine ribonucleotide metabolic processGO:0009150950.028
protein phosphorylationGO:0006468850.028
microtubule based processGO:00070171820.027
heterocycle biosynthetic processGO:00181301870.027
regulation of nucleotide catabolic processGO:0030811350.027
ras protein signal transductionGO:0007265310.027
nucleobase containing small molecule metabolic processGO:00550861150.027
anatomical structure homeostasisGO:0060249110.026
dna metabolic processGO:0006259740.026
positive regulation of calcium ion transportGO:005192810.026
secretionGO:00469031470.026
regulation of nucleotide metabolic processGO:0006140370.026
molting cycle collagen and cuticulin based cuticleGO:00189962810.026
cellular ion homeostasisGO:0006873110.025
phosphorus metabolic processGO:00067932320.025
cellular macromolecule biosynthetic processGO:00346452470.025
response to biotic stimulusGO:00096071010.025
programmed cell deathGO:00125015000.025
negative regulation of cellular metabolic processGO:0031324950.025
negative regulation of cellular biosynthetic processGO:0031327650.025
regulation of organelle organizationGO:00330431640.025
regulation of phosphate metabolic processGO:0019220810.024
organonitrogen compound metabolic processGO:19015641510.024
synaptic transmissionGO:00072681060.024
cellular localizationGO:00516413600.024
nervous system developmentGO:00073992530.024
regulation of phosphorus metabolic processGO:0051174810.023
ribonucleoside monophosphate metabolic processGO:0009161450.023
regulation of rna metabolic processGO:00512521730.023
macromolecule modificationGO:00434122180.023
positive regulation of nucleobase containing compound metabolic processGO:00459351340.023
protein modification processGO:00362112070.023
neuron differentiationGO:00301822170.023
positive regulation of nitrogen compound metabolic processGO:00511731340.023
protein localizationGO:00081042050.023
organelle fissionGO:00482853630.023
actin filament bundle assemblyGO:005101730.022
negative regulation of multicellular organismal processGO:00512412360.022
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.022
ribonucleoside metabolic processGO:0009119980.021
cellular response to organic substanceGO:00713101190.021
negative regulation of nitrogen compound metabolic processGO:0051172630.021
deathGO:00162655470.021
aromatic compound biosynthetic processGO:00194381920.021
positive regulation of gtp catabolic processGO:0033126280.021
response to woundingGO:000961140.021
regulation of gene expression epigeneticGO:00400291630.020
calcium ion homeostasisGO:005507460.020
positive regulation of cellular metabolic processGO:00313251780.020
regulation of transportGO:0051049910.020
gtp metabolic processGO:0046039460.020
mitotic nuclear divisionGO:0007067890.020
ribonucleoprotein complex assemblyGO:002261840.020
regulation of cell morphogenesisGO:0022604400.019
organic cyclic compound biosynthetic processGO:19013621950.019
hermaphrodite genitalia developmentGO:00400357340.019
membrane invaginationGO:0010324980.019
cellular response to chemical stimulusGO:00708871290.019
gtp catabolic processGO:0006184460.019
regulation of transcription from rna polymerase ii promoterGO:00063571450.019
regulation of cell developmentGO:0060284490.019
cell projection morphogenesisGO:00488581480.018
transcription from rna polymerase ii promoterGO:00063661490.018
positive regulation of purine nucleotide catabolic processGO:0033123280.018
regulation of signalingGO:00230511720.018
digestive system developmentGO:00551231220.018
rho protein signal transductionGO:000726620.018
feeding behaviorGO:0007631700.018
chromosome segregationGO:00070591800.018
backward locomotionGO:0043057110.018
regulation of response to stimulusGO:00485832430.018
negative regulation of cytosolic calcium ion concentrationGO:005148110.018
regulation of small gtpase mediated signal transductionGO:0051056410.018
divalent metal ion transportGO:0070838170.018
male anatomical structure morphogenesisGO:0090598780.017
positive regulation of hydrolase activityGO:0051345380.017
monovalent inorganic cation transportGO:0015672330.017
single organism catabolic processGO:00447121290.017
single organism behaviorGO:0044708830.017
purine ribonucleoside monophosphate metabolic processGO:0009167430.017
adult locomotory behaviorGO:000834410.017
regulation of macromolecule biosynthetic processGO:00105561890.017
apoptotic processGO:00069154780.016
phosphate containing compound metabolic processGO:00067962320.016
metal ion transportGO:0030001490.016
negative regulation of gene expressionGO:00106292170.016
regulation of localizationGO:00328791940.016
regulation of anatomical structure sizeGO:0090066460.016
regulation of actin cytoskeleton organizationGO:0032956170.016
nucleic acid templated transcriptionGO:00976591690.016
pattern specification processGO:0007389590.016
negative regulation of rna biosynthetic processGO:1902679530.016
positive regulation of metabolic processGO:00098931870.015
cellular protein complex disassemblyGO:0043624180.015
cell cell junction assemblyGO:000704320.015
cell divisionGO:00513012620.015
adult behaviorGO:003053430.015
cellular protein modification processGO:00064642070.015
regulation of signal transductionGO:00099661350.015
cell recognitionGO:0008037850.015
negative regulation of developmental processGO:00510932270.015
ribonucleoside monophosphate catabolic processGO:0009158280.015
small molecule metabolic processGO:00442811860.014
regulation of ion transportGO:0043269390.014
chemosensory behaviorGO:0007635330.014
negative regulation of nematode larval developmentGO:00610642080.014
negative regulation of biosynthetic processGO:0009890650.014
regulation of atp metabolic processGO:190357850.014
regulation of catabolic processGO:0009894570.014
regulation of secretionGO:0051046290.014
cell junction organizationGO:0034330180.013
cation homeostasisGO:0055080200.013
engulfment of apoptotic cellGO:0043652940.013
regulation of protein stabilityGO:003164730.013
regulation of actin filament polymerizationGO:0030833110.013
regulation of intracellular signal transductionGO:1902531770.013
response to oxygen containing compoundGO:1901700440.013
organic substance transportGO:00717021130.013
regulation of muscle cell differentiationGO:005114710.013
gene silencing by rnaGO:00310471430.013
apoptotic cell clearanceGO:00432771110.012
negative regulation of macromolecule biosynthetic processGO:0010558650.012
positive regulation of cysteine type endopeptidase activityGO:200105630.012
phagocytosis engulfmentGO:0006911980.012
membrane organizationGO:00610241350.012
posttranscriptional gene silencing by rnaGO:00351941430.012
ion transportGO:00068111130.012
cell morphogenesis involved in differentiationGO:00009041120.012
cellular metal ion homeostasisGO:000687570.012
locomotory behaviorGO:0007626400.012
regulation of calcium ion transportGO:005192430.012
positive regulation of nucleoside metabolic processGO:0045979280.011
regulation of cellular amine metabolic processGO:003323800.011
secretion by cellGO:00329401380.011
posttranscriptional gene silencingGO:00164411430.011
cellular protein metabolic processGO:00442672790.011
negative regulation of transcription dna templatedGO:0045892530.011
response to acid chemicalGO:000110140.011
regulation of nematode larval developmentGO:00610622600.011
sensory perception of bitter tasteGO:005091330.011
axonal fasciculationGO:0007413790.011
regulation of muscle contractionGO:0006937200.011
axon developmentGO:00615641630.011
regulation of anatomical structure morphogenesisGO:0022603510.010
single organism intracellular transportGO:1902582700.010
ribosome biogenesisGO:004225440.010
rna interferenceGO:00162461370.010
single organism membrane organizationGO:0044802350.010
nucleoside monophosphate catabolic processGO:0009125280.010
muscle thin filament assemblyGO:007168950.010
cell cycleGO:00070495260.010

unc-15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular diseaseDOID:008000000.186
disease of anatomical entityDOID:700.186
heart diseaseDOID:11400.186
myopathyDOID:42300.186
cardiomyopathyDOID:005070000.186
muscle tissue diseaseDOID:6600.186
musculoskeletal system diseaseDOID:1700.186
cardiovascular system diseaseDOID:128700.186
dilated cardiomyopathyDOID:1293000.051
intrinsic cardiomyopathyDOID:006003600.051
hypertrophic cardiomyopathyDOID:1198400.026
progeriaDOID:391100.017
skin diseaseDOID:3700.012
lipodystrophyDOID:81100.012
familial partial lipodystrophyDOID:005044000.012
integumentary system diseaseDOID:1600.012
disease of metabolismDOID:001466700.012
congenital muscular dystrophyDOID:005055700.011
muscular dystrophyDOID:988400.011
inherited metabolic disorderDOID:65500.011