Caenorhabditis elegans

57 known processes

rpn-6.1 (CELE_F57B9.10)

Protein RPN-6.1

rpn-6.1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.898
post embryonic developmentGO:000979121520.894
embryo developmentGO:000979030520.746
ubiquitin dependent protein catabolic processGO:0006511320.615
sexual reproductionGO:00199535460.603
gamete generationGO:00072764610.545
organ developmentGO:004851311020.537
multicellular organism reproductionGO:00325048190.532
proteolysis involved in cellular protein catabolic processGO:0051603320.532
germ cell developmentGO:00072813510.495
apoptotic processGO:00069154780.465
cellular catabolic processGO:00442481990.458
sex differentiationGO:00075489090.427
cell deathGO:00082195470.426
catabolic processGO:00090563180.419
developmental process involved in reproductionGO:000300611650.417
vulval developmentGO:00400253330.405
regulation of macromolecule metabolic processGO:00602554210.382
axon developmentGO:00615641630.382
protein metabolic processGO:00195384220.375
single organism reproductive processGO:004470211960.349
establishment of localizationGO:005123411710.348
regulation of developmental processGO:00507936840.342
cellular protein catabolic processGO:0044257370.342
multicellular organismal reproductive processGO:00486098150.328
locomotionGO:004001116340.326
agingGO:00075688120.312
macromolecule catabolic processGO:00090572020.308
vesicle mediated transportGO:00161928520.307
organelle organizationGO:00069967830.302
negative regulation of nematode larval developmentGO:00610642080.294
endocytosisGO:00068978190.280
hermaphrodite genitalia developmentGO:00400357340.269
modification dependent macromolecule catabolic processGO:0043632320.268
protein catabolic processGO:00301631620.259
cellular protein metabolic processGO:00442672790.252
organic substance catabolic processGO:19015752940.251
deathGO:00162655470.251
positive regulation of cellular processGO:00485223320.243
gene expressionGO:00104674120.229
regulation of vulval developmentGO:00400282480.229
regulation of metabolic processGO:00192224780.224
regulation of multicellular organismal processGO:00512397260.220
programmed cell deathGO:00125015000.217
positive regulation of nucleobase containing compound metabolic processGO:00459351340.216
regulation of nematode larval developmentGO:00610622600.213
transportGO:000681010930.212
multicellular organismal agingGO:00102598120.202
reproductive system developmentGO:00614588500.195
growthGO:00400075620.194
regulation of response to stimulusGO:00485832430.191
negative regulation of vulval developmentGO:00400272060.187
organic substance biosynthetic processGO:19015763230.184
cellular process involved in reproduction in multicellular organismGO:00224123510.182
regulation of cellular metabolic processGO:00313233050.174
cell projection organizationGO:00300302310.172
regulation of post embryonic developmentGO:00485802600.165
determination of adult lifespanGO:00083408120.164
signal transductionGO:00071653170.162
signalingGO:00230524010.159
positive regulation of macromolecule metabolic processGO:00106041490.155
body morphogenesisGO:00101716200.153
cytoskeleton organizationGO:00070103390.152
receptor mediated endocytosisGO:00068987150.151
cell cycleGO:00070495260.149
microtubule based processGO:00070171820.144
multicellular organismal reproductive behaviorGO:00330573840.140
regulation of growthGO:00400084090.139
small gtpase mediated signal transductionGO:0007264320.138
proteolysisGO:0006508610.134
proteasomal protein catabolic processGO:0010498200.131
reproductive structure developmentGO:00486088500.131
regulation of catabolic processGO:0009894570.128
ovipositionGO:00189913640.127
gonad developmentGO:00084068400.125
post embryonic organ developmentGO:00485693360.125
ras protein signal transductionGO:0007265310.123
oocyte axis specificationGO:000730920.122
cellular component movementGO:00069283880.122
cellular component biogenesisGO:00440852970.122
regulation of primary metabolic processGO:00800902920.121
reproductive behaviorGO:00190983870.120
regulation of biological qualityGO:00650087410.120
generation of neuronsGO:00486992350.119
regulation of developmental growthGO:00486383890.119
neuron differentiationGO:00301822170.118
ribonucleoside triphosphate metabolic processGO:0009199870.117
mitotic cell cycle processGO:19030471940.113
positive regulation of cellular metabolic processGO:00313251780.112
cell migrationGO:00164773060.110
fertilizationGO:0009566630.107
macromolecule biosynthetic processGO:00090592500.106
regulation of cellular catabolic processGO:0031329510.104
behaviorGO:00076105270.102
nucleobase containing small molecule metabolic processGO:00550861150.101
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.099
organophosphate metabolic processGO:00196371250.099
organophosphate catabolic processGO:0046434810.098
cellular macromolecule catabolic processGO:0044265730.097
single fertilizationGO:0007338610.097
phosphorus metabolic processGO:00067932320.097
regulation of multicellular organismal developmentGO:20000263170.097
single organism signalingGO:00447004010.094
cellular protein complex assemblyGO:00436231780.093
organelle fissionGO:00482853630.093
protein complex subunit organizationGO:00718222800.093
cellular macromolecule biosynthetic processGO:00346452470.093
multi organism reproductive processGO:00447038670.092
female gamete generationGO:00072922540.092
single organism organelle organizationGO:19025895010.089
regulation of cellular biosynthetic processGO:00313261890.089
single organism localizationGO:19025785180.088
cell motilityGO:00488703130.087
cell part morphogenesisGO:00329901520.085
neurogenesisGO:00220082360.085
phosphate containing compound metabolic processGO:00067962320.082
neuron developmentGO:00486661990.082
regulation of small gtpase mediated signal transductionGO:0051056410.080
biosynthetic processGO:00090583230.080
nervous system developmentGO:00073992530.080
regulation of rna biosynthetic processGO:20011411650.079
positive regulation of nitrogen compound metabolic processGO:00511731340.079
macromolecule localizationGO:00330367710.078
developmental growthGO:00485894120.078
single organism catabolic processGO:00447121290.074
nucleobase containing compound metabolic processGO:00061394060.073
positive regulation of metabolic processGO:00098931870.072
development of primary sexual characteristicsGO:00451378400.072
regulation of organelle organizationGO:00330431640.071
nucleic acid metabolic processGO:00903042990.071
maintenance of locationGO:00512355800.070
single organism transportGO:00447654470.070
response to organic substanceGO:00100331310.069
macromolecular complex subunit organizationGO:00439333200.067
regulation of ras protein signal transductionGO:0046578410.066
regulation of cell communicationGO:00106461760.066
regulation of signal transductionGO:00099661350.066
positive regulation of rna biosynthetic processGO:19026801020.066
macromolecule modificationGO:00434122180.065
response to abiotic stimulusGO:00096281520.065
regulation of multicellular organism growthGO:00400143730.065
muscle structure developmentGO:00610611910.065
positive regulation of growthGO:00459273690.064
nucleobase containing compound catabolic processGO:00346551140.063
positive regulation of neurogenesisGO:005076940.063
posttranscriptional regulation of gene expressionGO:00106081660.063
lipid localizationGO:00108765730.062
heterocycle catabolic processGO:00467001190.062
protein modification processGO:00362112070.061
purine ribonucleotide metabolic processGO:0009150950.061
meiotic cell cycleGO:00513213350.061
lipid storageGO:00199155650.060
cell divisionGO:00513012620.060
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243450.059
cell developmentGO:00484686960.059
spindle organizationGO:0007051920.058
small molecule metabolic processGO:00442811860.058
negative regulation of post embryonic developmentGO:00485812080.058
response to external stimulusGO:00096052890.057
negative regulation of biological processGO:00485195670.057
organic cyclic compound catabolic processGO:19013611190.057
receptor metabolic processGO:004311260.057
negative regulation of developmental processGO:00510932270.055
cell surface receptor signaling pathwayGO:00071661490.055
regulation of meiotic cell cycleGO:00514451360.055
regulation of catalytic activityGO:0050790780.055
oocyte constructionGO:000730820.054
regulation of signalingGO:00230511720.054
regulation of cellular component organizationGO:00511282480.054
oogenesisGO:00484772290.054
purine nucleotide metabolic processGO:0006163950.052
cell projection morphogenesisGO:00488581480.051
multi organism behaviorGO:00517053890.051
protein complex biogenesisGO:00702711860.051
nucleoside catabolic processGO:0009164780.051
organonitrogen compound metabolic processGO:19015641510.050
meiotic nuclear divisionGO:00071263000.050
cell cycle processGO:00224024820.049
positive regulation of multicellular organism growthGO:00400183520.049
positive regulation of developmental processGO:00510944080.048
negative regulation of metabolic processGO:00098922400.047
positive regulation of catalytic activityGO:0043085590.047
positive regulation of developmental growthGO:00486393540.047
meiotic chromosome segregationGO:00451321390.046
nucleoside phosphate metabolic processGO:00067531080.046
regulation of neuron differentiationGO:0045664400.045
nucleoside metabolic processGO:0009116990.045
positive regulation of multicellular organismal processGO:00512404170.045
multicellular organism growthGO:00352643850.045
negative regulation of cellular processGO:00485232390.044
axis specificationGO:0009798230.044
male gamete generationGO:0048232410.044
macromolecular complex assemblyGO:00650031930.043
purine containing compound metabolic processGO:0072521950.043
modification dependent protein catabolic processGO:0019941320.043
regulation of nucleobase containing compound metabolic processGO:00192192220.043
actin cytoskeleton organizationGO:00300361840.042
molting cycleGO:00423032810.042
regulation of phosphate metabolic processGO:0019220810.041
anatomical structure formation involved in morphogenesisGO:00486462500.041
regulation of protein metabolic processGO:0051246810.040
cellular response to chemical stimulusGO:00708871290.040
protein complex assemblyGO:00064611860.040
nucleotide metabolic processGO:00091171080.039
organelle localizationGO:00516401270.038
cellular protein modification processGO:00064642070.038
cellular response to stressGO:00335541620.038
establishment of localization in cellGO:00516493180.038
mitotic spindle organizationGO:0007052810.038
purine ribonucleoside metabolic processGO:0046128920.037
negative regulation of multicellular organismal processGO:00512412360.037
cellular component morphogenesisGO:00329893180.037
aromatic compound catabolic processGO:00194391160.037
digestive system developmentGO:00551231220.037
establishment of organelle localizationGO:00516561230.036
phagocytosisGO:00069091150.036
purine ribonucleoside triphosphate metabolic processGO:0009205870.034
neuron projection developmentGO:00311751870.034
localization of cellGO:00516743130.034
rna metabolic processGO:00160702280.034
purine nucleoside triphosphate metabolic processGO:0009144870.033
pronuclear migrationGO:0035046510.032
purine nucleoside triphosphate catabolic processGO:0009146720.032
ribonucleoside metabolic processGO:0009119980.032
organelle assemblyGO:00709252140.032
purine nucleoside catabolic processGO:0006152750.032
neuron projection guidanceGO:0097485820.031
membrane organizationGO:00610241350.031
regulation of nervous system developmentGO:0051960410.031
nucleobase containing compound biosynthetic processGO:00346541840.031
genitalia developmentGO:00488067410.030
regulation of cellular protein metabolic processGO:0032268750.030
ribonucleotide metabolic processGO:0009259990.030
gtp catabolic processGO:0006184460.030
mitotic g2 m transition checkpointGO:004481810.030
intracellular receptor signaling pathwayGO:003052220.030
purine ribonucleotide catabolic processGO:0009154750.029
actin filament based processGO:00300291910.029
protein localizationGO:00081042050.028
regulation of nitrogen compound metabolic processGO:00511712220.028
guanosine containing compound metabolic processGO:1901068490.028
ribonucleotide catabolic processGO:0009261750.028
carbohydrate derivative metabolic processGO:19011351410.028
chromosome segregationGO:00070591800.028
regulation of nuclear divisionGO:00517831150.028
purine ribonucleoside triphosphate catabolic processGO:0009207720.028
multi multicellular organism processGO:00447063900.028
positive regulation of cellular catabolic processGO:0031331350.028
carbohydrate derivative catabolic processGO:1901136820.027
negative regulation of macromolecule metabolic processGO:00106052290.027
regulation of cell proliferationGO:00421271050.027
positive regulation of phosphorylationGO:0042327270.027
negative regulation of cellular protein metabolic processGO:0032269270.026
cellular biosynthetic processGO:00442493150.026
negative regulation of gene expression epigeneticGO:004581420.026
digestive tract developmentGO:00485651220.026
cell morphogenesisGO:00009021630.026
multi organism reproductive behaviorGO:00447053870.026
cell morphogenesis involved in neuron differentiationGO:00486671110.026
cellular localizationGO:00516413600.026
purine nucleotide catabolic processGO:0006195750.026
cellular response to dna damage stimulusGO:0006974410.025
spermatogenesisGO:0007283410.025
regulation of cell differentiationGO:0045595810.025
regulation of multi organism processGO:0043900690.025
intracellular signal transductionGO:0035556960.024
regulation of cell divisionGO:00513021420.024
meiotic cell cycle processGO:19030461700.024
response to chemicalGO:00422213560.024
positive regulation of hydrolase activityGO:0051345380.023
negative regulation of cellular metabolic processGO:0031324950.023
symbiosis encompassing mutualism through parasitismGO:004440350.023
regulation of intracellular signal transductionGO:1902531770.023
negative regulation of protein metabolic processGO:0051248270.023
positive regulation of cellular component organizationGO:0051130340.023
oxidation reduction processGO:0055114590.023
muscle cell differentiationGO:00426921710.022
purine nucleoside metabolic processGO:0042278920.022
protein modification by small protein conjugation or removalGO:0070647400.022
regulation of nucleic acid templated transcriptionGO:19035061650.022
regulation of proteolysis involved in cellular protein catabolic processGO:190305050.022
negative regulation of chromosome segregationGO:005198540.022
aromatic compound biosynthetic processGO:00194381920.022
organonitrogen compound catabolic processGO:1901565900.021
regulation of gene expressionGO:00104683660.021
oxoacid metabolic processGO:0043436470.021
ribonucleoside triphosphate catabolic processGO:0009203720.021
chromosome organizationGO:00512761040.021
regulation of molecular functionGO:0065009890.020
transcription from rna polymerase ii promoterGO:00063661490.020
cellular macromolecular complex assemblyGO:00346221840.020
taxisGO:00423301280.020
positive regulation of purine nucleotide catabolic processGO:0033123280.020
glycosyl compound metabolic processGO:19016571000.020
nucleoside triphosphate metabolic processGO:0009141870.020
regulation of cell developmentGO:0060284490.020
glycosyl compound catabolic processGO:1901658790.020
organic acid metabolic processGO:0006082470.019
pattern specification processGO:0007389590.019
regulation of hydrolase activityGO:0051336450.019
apoptotic cell clearanceGO:00432771110.019
cellular component assemblyGO:00226072930.019
axon guidanceGO:0007411820.019
cell morphogenesis involved in differentiationGO:00009041120.019
rna biosynthetic processGO:00327741690.019
positive regulation of molecular functionGO:0044093610.018
nucleic acid templated transcriptionGO:00976591690.018
nucleotide catabolic processGO:0009166770.018
negative regulation of cell cycleGO:0045786530.018
regulation of mitosisGO:0007088180.018
guanosine containing compound catabolic processGO:1901069480.018
single organism carbohydrate metabolic processGO:0044723290.018
regulation of neurogenesisGO:0050767400.018
nuclear migrationGO:0007097540.018
tissue developmentGO:00098881120.017
protein modification by small protein conjugationGO:0032446310.017
negative regulation of gene expressionGO:00106292170.017
response to endogenous stimulusGO:0009719330.017
nucleoside triphosphate catabolic processGO:0009143720.017
carboxylic acid metabolic processGO:0019752340.017
regulation of biosynthetic processGO:00098891890.017
regulation of transcription dna templatedGO:00063551640.017
positive regulation of catabolic processGO:0009896380.017
positive regulation of nucleotide catabolic processGO:0030813280.017
response to mechanical stimulusGO:0009612280.017
molting cycle collagen and cuticulin based cuticleGO:00189962810.017
regulation of phosphorus metabolic processGO:0051174810.017
regulation of mitotic cell cycleGO:0007346760.017
positive regulation of intracellular signal transductionGO:1902533240.017
embryonic morphogenesisGO:00485981520.016
positive regulation of nucleoside metabolic processGO:0045979280.016
secretionGO:00469031470.016
regenerationGO:003109940.016
ribose phosphate metabolic processGO:0019693990.016
regulation of nucleotide metabolic processGO:0006140370.016
mitotic nuclear envelope reassemblyGO:000708430.016
sensory organ morphogenesisGO:009059620.016
positive regulation of phosphate metabolic processGO:0045937560.016
cell proliferationGO:00082831160.016
membrane invaginationGO:0010324980.016
tube developmentGO:00352951260.015
cellular nitrogen compound catabolic processGO:00442701190.015
regulation of localizationGO:00328791940.015
regulation of cell cycle processGO:00105641450.015
tissue morphogenesisGO:0048729650.015
ribonucleoside catabolic processGO:0042454770.015
regulation of cellular amine metabolic processGO:003323800.014
gene silencingGO:00164581430.014
negative regulation of cell communicationGO:0010648610.014
positive regulation of gene expressionGO:00106281120.014
purine ribonucleoside catabolic processGO:0046130750.014
neuron projection morphogenesisGO:00488121140.014
regulation of meiosisGO:0040020940.014
regionalizationGO:0003002310.014
single organism biosynthetic processGO:0044711910.014
organic cyclic compound biosynthetic processGO:19013621950.013
positive regulation of neuron differentiationGO:004566640.013
phagocytosis engulfmentGO:0006911980.013
centrosomal and pronuclear rotationGO:003504760.013
regulation of protein catabolic processGO:0042176130.013
regulation of rna metabolic processGO:00512521730.013
regulation of gene expression epigeneticGO:00400291630.013
engulfment of apoptotic cellGO:0043652940.013
heterocycle biosynthetic processGO:00181301870.013
golgi vesicle transportGO:004819330.013
cell cell signalingGO:00072671180.013
positive regulation of nucleotide metabolic processGO:0045981280.012
dendrite developmentGO:0016358420.012
response to woundingGO:000961140.012
negative regulation of mitotic sister chromatid segregationGO:003304840.012
regulation of protein stabilityGO:003164730.012
positive regulation of phosphorus metabolic processGO:0010562560.012
regulation of macromolecule biosynthetic processGO:00105561890.012
regulation of purine nucleotide metabolic processGO:1900542370.012
cell growthGO:0016049440.012
positive regulation of biosynthetic processGO:00098911090.012
cellular amine metabolic processGO:0044106150.012
cellular response to organic substanceGO:00713101190.012
positive regulation of cellular biosynthetic processGO:00313281090.012
negative regulation of macromolecule biosynthetic processGO:0010558650.012
muscle organ morphogenesisGO:004864440.011
positive regulation of transcription dna templatedGO:00458931020.011
positive regulation of rna metabolic processGO:00512541030.011
purine containing compound catabolic processGO:0072523750.011
generation of precursor metabolites and energyGO:0006091180.011
negative regulation of proteolysis involved in cellular protein catabolic processGO:190305140.011
regulation of nucleotide catabolic processGO:0030811350.011
nematode male tail tip morphogenesisGO:0045138770.011
cell cycle g1 s phase transitionGO:004484320.011
translationGO:0006412370.011
striated muscle cell differentiationGO:00511461580.011
maintenance of protein locationGO:0045185150.011
g1 s transition of mitotic cell cycleGO:000008220.011
regulation of apoptotic signaling pathwayGO:200123310.011
negative regulation of response to stimulusGO:0048585730.011
axonogenesisGO:00074091020.011
regulation of behaviorGO:0050795970.010
negative regulation of signalingGO:0023057610.010
cell cycle phase transitionGO:0044770190.010
regulation of purine nucleotide catabolic processGO:0033121350.010
protein ubiquitinationGO:0016567250.010
regulation of transcription from rna polymerase ii promoterGO:00063571450.010
posttranscriptional gene silencingGO:00164411430.010
attachment of spindle microtubules to kinetochoreGO:000860880.010
posttranscriptional gene silencing by rnaGO:00351941430.010
digestive tract morphogenesisGO:0048546760.010

rpn-6.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular diseaseDOID:008000000.014
muscular dystrophyDOID:988400.014
musculoskeletal system diseaseDOID:1700.014
muscle tissue diseaseDOID:6600.014
disease of anatomical entityDOID:700.014
myopathyDOID:42300.014
congenital muscular dystrophyDOID:005055700.014
disease of metabolismDOID:001466700.014
nervous system diseaseDOID:86300.012
inherited metabolic disorderDOID:65500.011