IMP: Integrative Multi-species Prediction

Caenorhabditis elegans

2 known processes

ftr-1 (CELE_Y113G7B.4)

Protein FTR-1

Entrez: 180320
UniProtKB: G5EC06

Process Predictions
Disease Predictions

ftr-1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
embryo development	GO:0009790	3052	0.699
embryo development ending in birth or egg hatching	GO:0009792	2992	0.689
locomotion	GO:0040011	1634	0.303
female gamete generation	GO:0007292	254	0.261	Worm
nervous system development	GO:0007399	253	0.191
actin cytoskeleton organization	GO:0030036	184	0.170	Worm
cellular component morphogenesis	GO:0032989	318	0.150	Worm
post embryonic development	GO:0009791	2152	0.140
actin filament based process	GO:0030029	191	0.136	Worm
muscle cell development	GO:0055001	158	0.124	Worm
multicellular organismal reproductive process	GO:0048609	815	0.124	Worm
organelle organization	GO:0006996	783	0.124	Worm
establishment of localization in cell	GO:0051649	318	0.121
multicellular organism reproduction	GO:0032504	819	0.113	Worm
establishment of localization	GO:0051234	1171	0.110
transport	GO:0006810	1093	0.104
single organism localization	GO:1902578	518	0.103
body morphogenesis	GO:0010171	620	0.102	Worm
muscle cell differentiation	GO:0042692	171	0.098	Worm
chromosome segregation	GO:0007059	180	0.095	Worm
growth	GO:0040007	562	0.094
regulation of developmental process	GO:0050793	684	0.093
protein complex assembly	GO:0006461	186	0.091	Worm
striated muscle cell development	GO:0055002	157	0.090	Worm
multicellular organism growth	GO:0035264	385	0.087
cell development	GO:0048468	696	0.085	Worm
endocytosis	GO:0006897	819	0.081
neurogenesis	GO:0022008	236	0.081
positive regulation of multicellular organismal process	GO:0051240	417	0.077
myofibril assembly	GO:0030239	154	0.076	Worm
cell cycle	GO:0007049	526	0.073	Worm
regulation of biological quality	GO:0065008	741	0.069
positive regulation of developmental process	GO:0051094	408	0.065
positive regulation of multicellular organism growth	GO:0040018	352	0.064
meiotic chromosome segregation	GO:0045132	139	0.063	Worm
gamete generation	GO:0007276	461	0.061	Worm
macromolecule localization	GO:0033036	771	0.061
meiotic cell cycle process	GO:1903046	170	0.061	Worm
receptor mediated endocytosis	GO:0006898	715	0.059
regulation of developmental growth	GO:0048638	389	0.058
regulation of multicellular organismal process	GO:0051239	726	0.057
macromolecular complex subunit organization	GO:0043933	320	0.057	Worm
cellular protein complex assembly	GO:0043623	178	0.056	Worm
maintenance of location	GO:0051235	580	0.056
cellular component movement	GO:0006928	388	0.056
developmental growth	GO:0048589	412	0.054
cellular process involved in reproduction in multicellular organism	GO:0022412	351	0.054	Worm
nuclear migration	GO:0007097	54	0.053
lipid storage	GO:0019915	565	0.053
cell migration	GO:0016477	306	0.053
cellular component biogenesis	GO:0044085	297	0.053	Worm
myosin filament assembly	GO:0031034	138	0.051	Worm
oogenesis	GO:0048477	229	0.051	Worm
protein complex subunit organization	GO:0071822	280	0.051	Worm
positive regulation of growth	GO:0045927	369	0.050
germ cell development	GO:0007281	351	0.050	Worm
generation of neurons	GO:0048699	235	0.048
regulation of growth	GO:0040008	409	0.048
developmental process involved in reproduction	GO:0003006	1165	0.047	Worm
lipid localization	GO:0010876	573	0.047
localization of cell	GO:0051674	313	0.047
cellular component assembly involved in morphogenesis	GO:0010927	183	0.047	Worm
actomyosin structure organization	GO:0031032	154	0.046	Worm
organelle assembly	GO:0070925	214	0.046	Worm
multi organism reproductive process	GO:0044703	867	0.044	Worm
striated muscle myosin thick filament assembly	GO:0071688	138	0.044	Worm
striated muscle cell differentiation	GO:0051146	158	0.044	Worm
regulation of multicellular organism growth	GO:0040014	373	0.043
sex differentiation	GO:0007548	909	0.043
cellular macromolecular complex assembly	GO:0034622	184	0.042	Worm
myosin filament organization	GO:0031033	138	0.042	Worm
cytoskeleton organization	GO:0007010	339	0.041	Worm
gonad development	GO:0008406	840	0.039
positive regulation of developmental growth	GO:0048639	354	0.038
meiotic cell cycle	GO:0051321	335	0.037	Worm
cellular biosynthetic process	GO:0044249	315	0.036
cellular component assembly	GO:0022607	293	0.034	Worm
anatomical structure formation involved in morphogenesis	GO:0048646	250	0.034	Worm
macromolecular complex assembly	GO:0065003	193	0.032	Worm
reproductive system development	GO:0061458	850	0.032
behavior	GO:0007610	527	0.032
multi organism behavior	GO:0051705	389	0.031
development of primary sexual characteristics	GO:0045137	840	0.031
innate immune response	GO:0045087	190	0.031
hermaphrodite genitalia development	GO:0040035	734	0.030
reproductive structure development	GO:0048608	850	0.030
genitalia development	GO:0048806	741	0.030
organic substance catabolic process	GO:1901575	294	0.029
neuron differentiation	GO:0030182	217	0.027
oviposition	GO:0018991	364	0.027
muscle structure development	GO:0061061	191	0.027	Worm
meiotic nuclear division	GO:0007126	300	0.027	Worm
multi multicellular organism process	GO:0044706	390	0.027
multicellular organismal aging	GO:0010259	812	0.027
nitrogen compound transport	GO:0071705	49	0.026
fertilization	GO:0009566	63	0.026
cell motility	GO:0048870	313	0.026
aging	GO:0007568	812	0.026
catabolic process	GO:0009056	318	0.025
organ development	GO:0048513	1102	0.025
positive regulation of cell cycle	GO:0045787	55	0.025
neuron development	GO:0048666	199	0.024
vesicle mediated transport	GO:0016192	852	0.024
organic substance transport	GO:0071702	113	0.024
molting cycle	GO:0042303	281	0.023
membrane organization	GO:0061024	135	0.023
molting cycle collagen and cuticulin based cuticle	GO:0018996	281	0.022
immune response	GO:0006955	192	0.022
nucleobase containing compound metabolic process	GO:0006139	406	0.022
single organism reproductive process	GO:0044702	1196	0.021	Worm
protein metabolic process	GO:0019538	422	0.021
regulation of macromolecule metabolic process	GO:0060255	421	0.021
protein complex biogenesis	GO:0070271	186	0.021	Worm
sexual reproduction	GO:0019953	546	0.020	Worm
rna transport	GO:0050658	3	0.020
protein catabolic process	GO:0030163	162	0.020
positive regulation of cellular metabolic process	GO:0031325	178	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	72	0.020
regulation of rna metabolic process	GO:0051252	173	0.019
cellular localization	GO:0051641	360	0.019
regulation of cellular macromolecule biosynthetic process	GO:2000112	188	0.019
multicellular organismal reproductive behavior	GO:0033057	384	0.019
protein localization	GO:0008104	205	0.018
single organism transport	GO:0044765	447	0.018
positive regulation of nitrogen compound metabolic process	GO:0051173	134	0.018
glycosyl compound metabolic process	GO:1901657	100	0.018
regulation of nitrogen compound metabolic process	GO:0051171	222	0.018
positive regulation of nucleobase containing compound metabolic process	GO:0045935	134	0.018
regulation of nucleobase containing compound metabolic process	GO:0019219	222	0.018
nucleus localization	GO:0051647	55	0.017
single fertilization	GO:0007338	61	0.017
determination of adult lifespan	GO:0008340	812	0.017
macromolecule catabolic process	GO:0009057	202	0.017
positive regulation of macromolecule metabolic process	GO:0010604	149	0.017
establishment of nucleus localization	GO:0040023	55	0.016
response to other organism	GO:0051707	101	0.016
death	GO:0016265	547	0.016
defense response to other organism	GO:0098542	100	0.016
protein neddylation	GO:0045116	3	0.016
establishment of rna localization	GO:0051236	3	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.015
nucleic acid transport	GO:0050657	3	0.015
positive regulation of biosynthetic process	GO:0009891	109	0.015
cellular amine metabolic process	GO:0044106	15	0.015
neuron projection development	GO:0031175	187	0.015
regulation of cellular amine metabolic process	GO:0033238	0	0.014
regulation of gene expression	GO:0010468	366	0.014
biosynthetic process	GO:0009058	323	0.014
cuticle development	GO:0042335	100	0.014
single organism organelle organization	GO:1902589	501	0.014	Worm
rna interference	GO:0016246	137	0.014
cell proliferation	GO:0008283	116	0.014
response to bacterium	GO:0009617	86	0.014
multi organism reproductive behavior	GO:0044705	387	0.013
rna localization	GO:0006403	3	0.013
regulation of cellular amino acid metabolic process	GO:0006521	0	0.013
regulation of organelle organization	GO:0033043	164	0.013
regulation of metabolic process	GO:0019222	478	0.013
purine ribonucleoside metabolic process	GO:0046128	92	0.013
reproductive behavior	GO:0019098	387	0.013
amine metabolic process	GO:0009308	15	0.013
regulation of cell proliferation	GO:0042127	105	0.013
cellular protein metabolic process	GO:0044267	279	0.013
regulation of macromolecule biosynthetic process	GO:0010556	189	0.013
cell projection organization	GO:0030030	231	0.012
germ line sex determination	GO:0018992	51	0.012	Worm
regulation of cellular component organization	GO:0051128	248	0.012
collagen and cuticulin based cuticle development	GO:0040002	99	0.012
cellular macromolecule biosynthetic process	GO:0034645	247	0.012
nematode male tail tip morphogenesis	GO:0045138	77	0.011
cellular amino acid metabolic process	GO:0006520	15	0.011
organelle fission	GO:0048285	363	0.011	Worm
signaling	GO:0023052	401	0.011
cellular catabolic process	GO:0044248	199	0.011
gene silencing by rna	GO:0031047	143	0.011
positive regulation of gene expression	GO:0010628	112	0.011
cellular ketone metabolic process	GO:0042180	14	0.011
response to chemical	GO:0042221	356	0.011
male anatomical structure morphogenesis	GO:0090598	78	0.011
ribose phosphate metabolic process	GO:0019693	99	0.011
vulval development	GO:0040025	333	0.011
regulation of cellular ph	GO:0030641	4	0.011
secretion	GO:0046903	147	0.010
defense response	GO:0006952	296	0.010
posttranscriptional regulation of gene expression	GO:0010608	166	0.010
macromolecule biosynthetic process	GO:0009059	250	0.010
regulation of primary metabolic process	GO:0080090	292	0.010
oxoacid metabolic process	GO:0043436	47	0.010

ftr-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.020

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