Caenorhabditis elegans

4 known processes

unc-1 (CELE_K03E6.5)

Protein UNC-1

unc-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell projection morphogenesisGO:00488581480.391
embryo development ending in birth or egg hatchingGO:000979229920.389
Worm
locomotionGO:004001116340.314
cell cycleGO:00070495260.290
single organism signalingGO:00447004010.277
organelle organizationGO:00069967830.249
cell morphogenesis involved in differentiationGO:00009041120.228
embryo developmentGO:000979030520.200
Worm
behaviorGO:00076105270.198
Worm
establishment of localizationGO:005123411710.194
Worm
taxisGO:00423301280.191
post embryonic developmentGO:000979121520.188
Worm
phosphate containing compound metabolic processGO:00067962320.155
regulation of response to stimulusGO:00485832430.132
cell cell signalingGO:00072671180.128
regulation of multicellular organismal processGO:00512397260.125
deathGO:00162655470.124
neurogenesisGO:00220082360.122
regulation of signalingGO:00230511720.108
cytoskeleton organizationGO:00070103390.107
chemotaxisGO:00069351200.103
single organism transportGO:00447654470.102
synaptic transmissionGO:00072681060.100
pronuclear migrationGO:0035046510.100
single organism organelle organizationGO:19025895010.097
regulation of biological qualityGO:00650087410.097
positive regulation of multicellular organismal processGO:00512404170.092
regulation of organelle organizationGO:00330431640.088
regulation of signal transductionGO:00099661350.084
vesicle mediated transportGO:00161928520.083
regulation of atp catabolic processGO:190328930.082
negative regulation of transporter activityGO:003241030.074
endocytosisGO:00068978190.074
regulation of phosphate metabolic processGO:0019220810.074
actin cytoskeleton organizationGO:00300361840.074
multicellular organismal reproductive processGO:00486098150.073
cellular component morphogenesisGO:00329893180.072
protein metabolic processGO:00195384220.070
Worm
growthGO:00400075620.069
Worm
neuron projection morphogenesisGO:00488121140.068
negative regulation of cellular processGO:00485232390.068
cell adhesionGO:0007155210.067
cell part morphogenesisGO:00329901520.065
transportGO:000681010930.065
cell morphogenesis involved in neuron differentiationGO:00486671110.064
positive regulation of metabolic processGO:00098931870.063
cell projection organizationGO:00300302310.062
establishment of vesicle localizationGO:0051650230.062
negative regulation of biological processGO:00485195670.061
regulation of cell communicationGO:00106461760.061
cell developmentGO:00484686960.060
regulation of phosphorus metabolic processGO:0051174810.060
regulation of multi organism processGO:0043900690.059
positive regulation of multicellular organism growthGO:00400183520.059
gonad developmentGO:00084068400.059
developmental process involved in reproductionGO:000300611650.058
sensory organ morphogenesisGO:009059620.057
multicellular organismal agingGO:00102598120.057
synaptic vesicle endocytosisGO:004848830.056
organelle fissionGO:00482853630.055
negative regulation of cation channel activityGO:200125820.054
multicellular organism growthGO:00352643850.053
cell morphogenesisGO:00009021630.052
single organism behaviorGO:0044708830.052
Worm
positive regulation of developmental processGO:00510944080.051
regulation of growthGO:00400084090.051
positive regulation of cellular metabolic processGO:00313251780.051
establishment of organelle localizationGO:00516561230.050
multicellular organism reproductionGO:00325048190.048
positive regulation of growthGO:00459273690.048
regulation of cellular component organizationGO:00511282480.048
regulation of developmental processGO:00507936840.048
cellular component movementGO:00069283880.048
regulation of developmental growthGO:00486383890.048
determination of adult lifespanGO:00083408120.047
meiotic cell cycleGO:00513213350.047
body morphogenesisGO:00101716200.047
lipid localizationGO:00108765730.047
macromolecule localizationGO:00330367710.046
Worm
organelle assemblyGO:00709252140.046
lipid storageGO:00199155650.046
multi organism behaviorGO:00517053890.045
cell deathGO:00082195470.044
agingGO:00075688120.043
developmental growthGO:00485894120.043
neurotransmitter transportGO:0006836320.043
meiotic nuclear divisionGO:00071263000.043
signal transductionGO:00071653170.042
actin filament based processGO:00300291910.042
maintenance of locationGO:00512355800.041
ion transportGO:00068111130.041
regulation of multicellular organism growthGO:00400143730.041
positive regulation of signalingGO:0023056660.040
neuron differentiationGO:00301822170.040
positive regulation of cellular processGO:00485223320.040
programmed cell deathGO:00125015000.039
positive regulation of developmental growthGO:00486393540.038
epithelial tube morphogenesisGO:006056210.038
single organism localizationGO:19025785180.038
reproductive structure developmentGO:00486088500.038
development of primary sexual characteristicsGO:00451378400.037
muscle cell developmentGO:00550011580.037
regulation of synaptic plasticityGO:004816710.036
cell migrationGO:00164773060.035
cell growthGO:0016049440.034
embryonic morphogenesisGO:00485981520.034
synaptic vesicle recyclingGO:003646530.034
reproductive system developmentGO:00614588500.033
myofibril assemblyGO:00302391540.033
synaptic vesicle transportGO:0048489210.032
genitalia developmentGO:00488067410.032
signalingGO:00230524010.032
negative regulation of ion transmembrane transportGO:003476630.031
multi organism reproductive processGO:00447038670.031
macromolecular complex subunit organizationGO:00439333200.031
cell cycle processGO:00224024820.031
single organism reproductive processGO:004470211960.031
axon guidanceGO:0007411820.030
cellular localizationGO:00516413600.030
cellular component assemblyGO:00226072930.030
cellular biosynthetic processGO:00442493150.030
response to external stimulusGO:00096052890.030
Worm
positive regulation of signal transductionGO:0009967400.029
establishment of nucleus localizationGO:0040023550.028
regulation of molecular functionGO:0065009890.028
nervous system developmentGO:00073992530.028
regulation of cellular metabolic processGO:00313233050.027
inactivation of mapkkk activityGO:005139020.027
actomyosin structure organizationGO:00310321540.027
generation of neuronsGO:00486992350.027
muscle cell differentiationGO:00426921710.027
regulation of multicellular organismal developmentGO:20000263170.027
microtubule based processGO:00070171820.027
regulation of localizationGO:00328791940.026
reproductive behaviorGO:00190983870.026
muscle structure developmentGO:00610611910.026
cell divisionGO:00513012620.026
apoptotic processGO:00069154780.026
cell matrix adhesionGO:000716010.025
catabolic processGO:00090563180.025
Worm
regulation of atpase activityGO:004346230.025
positive regulation of cell communicationGO:0010647690.024
nucleus localizationGO:0051647550.024
peptidyl serine phosphorylationGO:0018105200.024
regulation of locomotionGO:00400121610.024
regulation of phosphorylationGO:0042325450.024
protein modification processGO:00362112070.024
multi multicellular organism processGO:00447063900.023
ion transmembrane transportGO:0034220910.023
positive regulation of cell migrationGO:003033530.023
defense responseGO:00069522960.023
regulation of cell cycleGO:00517261940.023
negative regulation of transmembrane transportGO:003476330.023
negative regulation of ion transmembrane transporter activityGO:003241330.023
regulation of metabolic processGO:00192224780.022
macromolecule modificationGO:00434122180.022
membrane organizationGO:00610241350.022
regulation of neurotransmitter levelsGO:0001505360.022
protein complex biogenesisGO:00702711860.022
positive regulation of intracellular signal transductionGO:1902533240.022
fertilizationGO:0009566630.022
regulation of cell deathGO:0010941650.022
mitotic cell cycle processGO:19030471940.022
germ cell developmentGO:00072813510.022
monovalent inorganic cation transportGO:0015672330.021
peptidyl serine modificationGO:0018209200.021
cell motilityGO:00488703130.021
phosphorus metabolic processGO:00067932320.021
intracellular signal transductionGO:0035556960.021
cell substrate adhesionGO:003158910.021
organelle localizationGO:00516401270.021
receptor mediated endocytosisGO:00068987150.021
cell cycle phase transitionGO:0044770190.021
negative regulation of multicellular organismal processGO:00512412360.021
localization of cellGO:00516743130.021
establishment of localization in cellGO:00516493180.021
cell type specific apoptotic processGO:009728540.021
cellular process involved in reproduction in multicellular organismGO:00224123510.020
cellular component assembly involved in morphogenesisGO:00109271830.020
epithelial cell proliferationGO:005067310.020
oocyte axis specificationGO:000730920.020
positive regulation of rna metabolic processGO:00512541030.020
sexual reproductionGO:00199535460.020
striated muscle cell differentiationGO:00511461580.020
signal transduction by phosphorylationGO:0023014310.020
response to chemicalGO:00422213560.020
regulation of apoptotic signaling pathwayGO:200123310.020
cellular protein complex assemblyGO:00436231780.020
lipid metabolic processGO:0006629770.019
cellular macromolecular complex assemblyGO:00346221840.019
sex differentiationGO:00075489090.019
lamellipodium assemblyGO:003003220.019
negative regulation of cell cycleGO:0045786530.018
eating behaviorGO:0042755590.018
muscle system processGO:0003012430.018
response to abiotic stimulusGO:00096281520.018
Worm
feeding behaviorGO:0007631700.018
learning or memoryGO:0007611270.018
protein complex subunit organizationGO:00718222800.018
establishment of protein localization to membraneGO:009015030.018
multi organism reproductive behaviorGO:00447053870.018
single organism membrane fusionGO:0044801130.017
ovipositionGO:00189913640.017
regulation of nitrogen compound metabolic processGO:00511712220.017
regulation of behaviorGO:0050795970.017
organ developmentGO:004851311020.017
regulation of cell proliferationGO:00421271050.017
multicellular organismal reproductive behaviorGO:00330573840.017
cation transmembrane transportGO:0098655590.017
intracellular transportGO:0046907770.017
biological adhesionGO:0022610210.017
cellular protein modification processGO:00064642070.017
positive regulation of phosphorus metabolic processGO:0010562560.017
cellular protein metabolic processGO:00442672790.017
regulation of nucleobase containing compound metabolic processGO:00192192220.017
detection of external stimulusGO:000958140.017
mitotic nuclear divisionGO:0007067890.016
vesicle localizationGO:0051648240.016
regulation of anatomical structure sizeGO:0090066460.016
regulation of exocytosisGO:001715710.016
macromolecular complex assemblyGO:00650031930.016
tissue developmentGO:00098881120.016
muscle organ morphogenesisGO:004864440.016
response to woundingGO:000961140.016
cellular component biogenesisGO:00440852970.016
organic substance catabolic processGO:19015752940.016
Worm
axon developmentGO:00615641630.016
axonogenesisGO:00074091020.016
positive regulation of response to stimulusGO:0048584550.015
neuron developmentGO:00486661990.015
regulation of macromolecule metabolic processGO:00602554210.015
positive regulation of nitrogen compound metabolic processGO:00511731340.015
negative regulation of cell morphogenesis involved in differentiationGO:001077120.015
negative regulation of cell communicationGO:0010648610.015
regulation of cation channel activityGO:200125730.015
hermaphrodite genitalia developmentGO:00400357340.015
integrin mediated signaling pathwayGO:000722910.014
cell fate commitmentGO:00451651390.014
striated muscle cell developmentGO:00550021570.014
macromolecule catabolic processGO:00090572020.014
Worm
positive regulation of intracellular transportGO:003238820.014
gamete generationGO:00072764610.014
anatomical structure homeostasisGO:0060249110.014
regulation of protein targetingGO:190353330.014
positive regulation of molecular functionGO:0044093610.014
regulation of cellular biosynthetic processGO:00313261890.014
muscle cell cellular homeostasisGO:004671650.014
regulation of filopodium assemblyGO:005148920.014
transmembrane transportGO:00550851100.014
positive regulation of gene expressionGO:00106281120.014
single organism intracellular transportGO:1902582700.013
regulation of intracellular signal transductionGO:1902531770.013
head developmentGO:006032210.013
neuron neuron synaptic transmissionGO:0007270220.013
negative regulation of protein metabolic processGO:0051248270.013
organelle fusionGO:004828480.013
inductive cell migrationGO:00400391450.013
single fertilizationGO:0007338610.013
positive regulation of cellular component organizationGO:0051130340.013
positive regulation of phosphate metabolic processGO:0045937560.013
regulation of epithelial cell differentiationGO:003085640.013
response to biotic stimulusGO:00096071010.013
regulation of programmed cell deathGO:0043067500.013
membrane fusionGO:0061025160.013
regulation of neuromuscular synaptic transmissionGO:190007310.013
embryonic body morphogenesisGO:0010172490.012
meiotic cell cycle processGO:19030461700.012
oxoacid metabolic processGO:0043436470.012
regulation of transportGO:0051049910.012
regulation of cell cycle processGO:00105641450.012
positive regulation of cell projection organizationGO:003134640.012
regulation of lamellipodium organizationGO:190274310.012
striated muscle myosin thick filament assemblyGO:00716881380.012
regulation of catalytic activityGO:0050790780.012
negative regulation of neurogenesisGO:005076840.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of protein transportGO:005122240.012
homeostatic processGO:0042592510.012
myosin filament organizationGO:00310331380.012
myosin filament assemblyGO:00310341380.012
posttranscriptional regulation of gene expressionGO:00106081660.012
organic substance transportGO:00717021130.012
oocyte constructionGO:000730820.012
anatomical structure formation involved in morphogenesisGO:00486462500.012
system processGO:00030081360.012
vesicle organizationGO:0016050150.012
regulation of cellular protein metabolic processGO:0032268750.012
regulation of cytoplasmic transportGO:190364930.012
positive regulation of phosphorylationGO:0042327270.011
detection of abiotic stimulusGO:000958240.011
sex determinationGO:0007530600.011
positive regulation of cell morphogenesis involved in differentiationGO:001077040.011
pharyngeal pumpingGO:0043050580.011
negative regulation of signalingGO:0023057610.011
regulation of gene expressionGO:00104683660.011
lamellipodium organizationGO:009758120.011
neuron projection guidanceGO:0097485820.011
molting cycle collagen and cuticulin based cuticleGO:00189962810.011
positive regulation of macromolecule metabolic processGO:00106041490.011
nucleobase containing compound metabolic processGO:00061394060.011
regulation of system processGO:0044057270.011
regulation of epithelial cell proliferationGO:005067810.011
regulation of primary metabolic processGO:00800902920.011
small molecule metabolic processGO:00442811860.011
cell surface receptor signaling pathwayGO:00071661490.011
nuclear migrationGO:0007097540.010
positive regulation of cell deathGO:0010942380.010
negative regulation of gene expressionGO:00106292170.010
response to external biotic stimulusGO:00432071010.010
water homeostasisGO:003010450.010
cellular catabolic processGO:00442481990.010
cation transportGO:0006812780.010
negative regulation of developmental processGO:00510932270.010
muscle tissue developmentGO:006053710.010

unc-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
intrinsic cardiomyopathyDOID:006003600.032
disease of anatomical entityDOID:700.032
cardiomyopathyDOID:005070000.032
musculoskeletal system diseaseDOID:1700.032
muscle tissue diseaseDOID:6600.032
cardiovascular system diseaseDOID:128700.032
myopathyDOID:42300.032
heart diseaseDOID:11400.032
hypertrophic cardiomyopathyDOID:1198400.032
muscular diseaseDOID:008000000.032