IMP: Integrative Multi-species Prediction

Caenorhabditis elegans

54 known processes

sqv-4 (CELE_F29F11.1)

Protein SQV-4

Entrez: 179484
UniProtKB: Q19905

Process Predictions
Disease Predictions

sqv-4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
embryo development	GO:0009790	3052	0.751
post embryonic development	GO:0009791	2152	0.662
establishment of localization	GO:0051234	1171	0.648
organ development	GO:0048513	1102	0.636
embryo development ending in birth or egg hatching	GO:0009792	2992	0.611
genitalia development	GO:0048806	741	0.553
regulation of primary metabolic process	GO:0080090	292	0.531
multicellular organism reproduction	GO:0032504	819	0.482
single organism localization	GO:1902578	518	0.434
epithelium development	GO:0060429	68	0.433
cellular protein modification process	GO:0006464	207	0.429
single organism transport	GO:0044765	447	0.413
transport	GO:0006810	1093	0.412
cellular localization	GO:0051641	360	0.410
multicellular organismal aging	GO:0010259	812	0.404
endocytosis	GO:0006897	819	0.392
nucleobase containing compound metabolic process	GO:0006139	406	0.340
protein metabolic process	GO:0019538	422	0.328
single fertilization	GO:0007338	61	0.324
vesicle mediated transport	GO:0016192	852	0.314
programmed cell death	GO:0012501	500	0.301
signal transduction	GO:0007165	317	0.295
sexual reproduction	GO:0019953	546	0.289
development of primary sexual characteristics	GO:0045137	840	0.270
cellular protein metabolic process	GO:0044267	279	0.258
apoptotic process	GO:0006915	478	0.254
establishment of localization in cell	GO:0051649	318	0.249
protein catabolic process	GO:0030163	162	0.236
developmental process involved in reproduction	GO:0003006	1165	0.233
receptor mediated endocytosis	GO:0006898	715	0.230
regulation of cellular metabolic process	GO:0031323	305	0.225
vulval development	GO:0040025	333	0.219
multicellular organismal reproductive process	GO:0048609	815	0.216
locomotion	GO:0040011	1634	0.195
protein localization	GO:0008104	205	0.194
multicellular organism growth	GO:0035264	385	0.191
response to chemical	GO:0042221	356	0.185
gonad development	GO:0008406	840	0.184
secretion	GO:0046903	147	0.181
macromolecule modification	GO:0043412	218	0.179
reproductive structure development	GO:0048608	850	0.177
tissue development	GO:0009888	112	0.175
pronuclear migration	GO:0035046	51	0.174
sex differentiation	GO:0007548	909	0.173
biosynthetic process	GO:0009058	323	0.171
organic substance catabolic process	GO:1901575	294	0.169
fertilization	GO:0009566	63	0.169
regulation of multicellular organism growth	GO:0040014	373	0.169
multi organism reproductive process	GO:0044703	867	0.168
gamete generation	GO:0007276	461	0.163
regulation of nucleobase containing compound metabolic process	GO:0019219	222	0.162
macromolecule localization	GO:0033036	771	0.155
molting cycle collagen and cuticulin based cuticle	GO:0018996	281	0.151
macromolecular complex subunit organization	GO:0043933	320	0.145
regulation of macromolecule metabolic process	GO:0060255	421	0.144
head development	GO:0060322	1	0.139
single organism reproductive process	GO:0044702	1196	0.135
hermaphrodite genitalia development	GO:0040035	734	0.134
regulation of growth	GO:0040008	409	0.133
cell surface receptor signaling pathway	GO:0007166	149	0.131
regulation of catalytic activity	GO:0050790	78	0.125
positive regulation of multicellular organismal process	GO:0051240	417	0.124
positive regulation of growth	GO:0045927	369	0.124
catabolic process	GO:0009056	318	0.120
protein modification process	GO:0036211	207	0.119
cellular component assembly	GO:0022607	293	0.117
cell development	GO:0048468	696	0.116
cellular protein complex assembly	GO:0043623	178	0.115
cell cycle process	GO:0022402	482	0.114
reproductive system development	GO:0061458	850	0.113
regulation of multicellular organismal development	GO:2000026	317	0.112
protein complex subunit organization	GO:0071822	280	0.109
single organism organelle organization	GO:1902589	501	0.108
cell death	GO:0008219	547	0.108
death	GO:0016265	547	0.105
cellular biosynthetic process	GO:0044249	315	0.104
macromolecule catabolic process	GO:0009057	202	0.104
organic substance biosynthetic process	GO:1901576	323	0.103
determination of adult lifespan	GO:0008340	812	0.100
positive regulation of multicellular organism growth	GO:0040018	352	0.099
organelle organization	GO:0006996	783	0.098
signaling	GO:0023052	401	0.098
regulation of multicellular organismal process	GO:0051239	726	0.095
cellular catabolic process	GO:0044248	199	0.094
positive regulation of developmental process	GO:0051094	408	0.092
germ cell development	GO:0007281	351	0.091
regulation of nitrogen compound metabolic process	GO:0051171	222	0.091
negative regulation of biological process	GO:0048519	567	0.091
positive regulation of developmental growth	GO:0048639	354	0.091
meiotic cell cycle	GO:0051321	335	0.090
organelle localization	GO:0051640	127	0.089
nucleus localization	GO:0051647	55	0.088
regulation of localization	GO:0032879	194	0.083
cellular response to stress	GO:0033554	162	0.081
negative regulation of cellular process	GO:0048523	239	0.081
rna metabolic process	GO:0016070	228	0.080
phosphorus metabolic process	GO:0006793	232	0.078
multicellular organismal reproductive behavior	GO:0033057	384	0.077
body morphogenesis	GO:0010171	620	0.077
regulation of helicase activity	GO:0051095	2	0.077
cellular macromolecule biosynthetic process	GO:0034645	247	0.077
organic substance transport	GO:0071702	113	0.074
regulation of molecular function	GO:0065009	89	0.074
cytoskeleton organization	GO:0007010	339	0.073
protein complex assembly	GO:0006461	186	0.070
protein complex biogenesis	GO:0070271	186	0.069
single organism intracellular transport	GO:1902582	70	0.069
organonitrogen compound metabolic process	GO:1901564	151	0.069
intracellular transport	GO:0046907	77	0.067
cellular component biogenesis	GO:0044085	297	0.067
growth	GO:0040007	562	0.065
cellular macromolecular complex assembly	GO:0034622	184	0.064
regulation of developmental process	GO:0050793	684	0.063
regulation of biological quality	GO:0065008	741	0.063
cell division	GO:0051301	262	0.062
molting cycle	GO:0042303	281	0.062
regulation of rna biosynthetic process	GO:2001141	165	0.061
maintenance of location	GO:0051235	580	0.060
nuclear migration	GO:0007097	54	0.060
negative regulation of macromolecule metabolic process	GO:0010605	229	0.059
establishment of nucleus localization	GO:0040023	55	0.058
lipid localization	GO:0010876	573	0.058
lipid storage	GO:0019915	565	0.057
macromolecular complex assembly	GO:0065003	193	0.057
collagen and cuticulin based cuticle development	GO:0040002	99	0.057
single organism signaling	GO:0044700	401	0.057
female gamete generation	GO:0007292	254	0.053
membrane organization	GO:0061024	135	0.052
regulation of developmental growth	GO:0048638	389	0.051
aging	GO:0007568	812	0.051
post embryonic organ development	GO:0048569	336	0.050
cell cycle	GO:0007049	526	0.050
negative regulation of metabolic process	GO:0009892	240	0.050
positive regulation of cellular process	GO:0048522	332	0.050
small molecule metabolic process	GO:0044281	186	0.049
cuticle development	GO:0042335	100	0.048
microtubule polymerization or depolymerization	GO:0031109	22	0.048
cytokinesis	GO:0000910	80	0.048
regulation of gene expression	GO:0010468	366	0.047
transcription from rna polymerase ii promoter	GO:0006366	149	0.047
cellular nitrogen compound catabolic process	GO:0044270	119	0.047
cell motility	GO:0048870	313	0.046
phosphate containing compound metabolic process	GO:0006796	232	0.045
regulation of phosphorus metabolic process	GO:0051174	81	0.045
nervous system development	GO:0007399	253	0.044
response to organic substance	GO:0010033	131	0.044
oviposition	GO:0018991	364	0.044
aromatic compound biosynthetic process	GO:0019438	192	0.043
microtubule based process	GO:0007017	182	0.042
developmental growth	GO:0048589	412	0.042
regulation of transcription dna templated	GO:0006355	164	0.042
regulation of biosynthetic process	GO:0009889	189	0.042
regulation of response to stimulus	GO:0048583	243	0.041
oxoacid metabolic process	GO:0043436	47	0.041
positive regulation of catalytic activity	GO:0043085	59	0.040
oogenesis	GO:0048477	229	0.039
organic acid metabolic process	GO:0006082	47	0.039
actin filament based process	GO:0030029	191	0.039
macromolecule biosynthetic process	GO:0009059	250	0.039
nucleic acid metabolic process	GO:0090304	299	0.039
transmembrane transport	GO:0055085	110	0.038
ion transmembrane transport	GO:0034220	91	0.038
heterocycle catabolic process	GO:0046700	119	0.037
muscle cell differentiation	GO:0042692	171	0.036
regulation of cellular biosynthetic process	GO:0031326	189	0.036
guanosine containing compound catabolic process	GO:1901069	48	0.036
reproductive behavior	GO:0019098	387	0.035
cellular component movement	GO:0006928	388	0.034
single organism behavior	GO:0044708	83	0.034
regulation of signaling	GO:0023051	172	0.033
ion transport	GO:0006811	113	0.033
regulation of metabolic process	GO:0019222	478	0.033
carbohydrate derivative metabolic process	GO:1901135	141	0.033
protein modification by small protein conjugation or removal	GO:0070647	40	0.033
anatomical structure formation involved in morphogenesis	GO:0048646	250	0.033	Zebrafish
regulation of macromolecule biosynthetic process	GO:0010556	189	0.033
positive regulation of cellular metabolic process	GO:0031325	178	0.033
cellular response to dna damage stimulus	GO:0006974	41	0.031
proteolysis	GO:0006508	61	0.031
regulation of cell cycle	GO:0051726	194	0.031
organelle assembly	GO:0070925	214	0.031
cellular process involved in reproduction in multicellular organism	GO:0022412	351	0.031
multi organism reproductive behavior	GO:0044705	387	0.031
positive regulation of neurogenesis	GO:0050769	4	0.030
protein transport	GO:0015031	45	0.030
meiotic nuclear division	GO:0007126	300	0.029
cell proliferation	GO:0008283	116	0.029
tissue morphogenesis	GO:0048729	65	0.029
localization of cell	GO:0051674	313	0.029
actin cytoskeleton organization	GO:0030036	184	0.029
cell projection organization	GO:0030030	231	0.028
single organism biosynthetic process	GO:0044711	91	0.027
regulation of transport	GO:0051049	91	0.025
response to abiotic stimulus	GO:0009628	152	0.025
negative regulation of nematode larval development	GO:0061064	208	0.025
regulation of cellular component organization	GO:0051128	248	0.025
system process	GO:0003008	136	0.025
positive regulation of intracellular transport	GO:0032388	2	0.024
nucleobase containing small molecule metabolic process	GO:0055086	115	0.024
purine nucleoside catabolic process	GO:0006152	75	0.024
cell migration	GO:0016477	306	0.024
regulation of cell cycle process	GO:0010564	145	0.024
purine ribonucleoside triphosphate metabolic process	GO:0009205	87	0.023
regulation of cell proliferation	GO:0042127	105	0.023
cellular protein localization	GO:0034613	75	0.023
regulation of gene expression epigenetic	GO:0040029	163	0.023
multi multicellular organism process	GO:0044706	390	0.023
cytoskeleton dependent cytokinesis	GO:0061640	35	0.023
cellular response to organic substance	GO:0071310	119	0.023
cellular macromolecule localization	GO:0070727	75	0.022
nucleotide catabolic process	GO:0009166	77	0.022
behavior	GO:0007610	527	0.022
regulation of signal transduction	GO:0009966	135	0.022
organic cyclic compound catabolic process	GO:1901361	119	0.022
regulation of hydrolase activity	GO:0051336	45	0.022
posttranscriptional gene silencing by rna	GO:0035194	143	0.021
secretion by cell	GO:0032940	138	0.021
negative regulation of vulval development	GO:0040027	206	0.021
mitotic cell cycle process	GO:1903047	194	0.021
gene silencing	GO:0016458	143	0.021
gtp catabolic process	GO:0006184	46	0.021
transcription dna templated	GO:0006351	168	0.021
nucleoside metabolic process	GO:0009116	99	0.021
ribose phosphate metabolic process	GO:0019693	99	0.021
muscle structure development	GO:0061061	191	0.020
heterocycle biosynthetic process	GO:0018130	187	0.020
homeostatic process	GO:0042592	51	0.020
negative regulation of mitotic cell cycle phase transition	GO:1901991	5	0.020
negative regulation of nucleobase containing compound metabolic process	GO:0045934	63	0.020
response to external stimulus	GO:0009605	289	0.020
modification dependent protein catabolic process	GO:0019941	32	0.020
oocyte axis specification	GO:0007309	2	0.020
positive regulation of neuron differentiation	GO:0045666	4	0.020
striated muscle myosin thick filament assembly	GO:0071688	138	0.020
ovulation	GO:0030728	33	0.020
actomyosin structure organization	GO:0031032	154	0.019
carboxylic acid metabolic process	GO:0019752	34	0.019
phagocytosis engulfment	GO:0006911	98	0.019
nucleoside phosphate metabolic process	GO:0006753	108	0.018
gene expression	GO:0010467	412	0.018
negative regulation of multicellular organismal process	GO:0051241	236	0.018
mitotic spindle stabilization	GO:0043148	2	0.018
establishment of organelle localization	GO:0051656	123	0.018
mitotic spindle organization	GO:0007052	81	0.018
mitotic g2 m transition checkpoint	GO:0044818	1	0.018
proteolysis involved in cellular protein catabolic process	GO:0051603	32	0.018
positive regulation of metabolic process	GO:0009893	187	0.018
carbohydrate metabolic process	GO:0005975	34	0.018
protein dna complex assembly	GO:0065004	7	0.018
purine nucleoside triphosphate metabolic process	GO:0009144	87	0.018
chromosome organization	GO:0051276	104	0.018
nucleic acid templated transcription	GO:0097659	169	0.017
regulation of cytoplasmic transport	GO:1903649	3	0.017
microtubule based movement	GO:0007018	33	0.017
nucleotide metabolic process	GO:0009117	108	0.017
posttranscriptional gene silencing	GO:0016441	143	0.017
response to inorganic substance	GO:0010035	50	0.017
cilium assembly	GO:0042384	28	0.017
response to wounding	GO:0009611	4	0.017
carbohydrate derivative biosynthetic process	GO:1901137	46	0.017
negative regulation of gene expression	GO:0010629	217	0.017
striated muscle cell differentiation	GO:0051146	158	0.016
regulation of cell differentiation	GO:0045595	81	0.016
purine ribonucleotide catabolic process	GO:0009154	75	0.016
positive regulation of nucleic acid templated transcription	GO:1903508	102	0.016
establishment of protein localization	GO:0045184	50	0.016
ribonucleoside metabolic process	GO:0009119	98	0.016
purine nucleoside metabolic process	GO:0042278	92	0.016
nucleobase containing compound biosynthetic process	GO:0034654	184	0.016
gene silencing by rna	GO:0031047	143	0.016
membrane invagination	GO:0010324	98	0.016
ribonucleoside triphosphate catabolic process	GO:0009203	72	0.016
neurogenesis	GO:0022008	236	0.016
er associated ubiquitin dependent protein catabolic process	GO:0030433	6	0.016
regulation of nucleic acid templated transcription	GO:1903506	165	0.016
aromatic compound catabolic process	GO:0019439	116	0.016
spindle organization	GO:0007051	92	0.015
myofibril assembly	GO:0030239	154	0.015
asymmetric cell division	GO:0008356	36	0.015
purine ribonucleoside metabolic process	GO:0046128	92	0.015
positive regulation of macromolecule metabolic process	GO:0010604	149	0.015
positive regulation of cell migration	GO:0030335	3	0.015
regulation of phosphate metabolic process	GO:0019220	81	0.015
mechanosensory behavior	GO:0007638	25	0.015
regulation of organelle organization	GO:0033043	164	0.015
organic cyclic compound biosynthetic process	GO:1901362	195	0.015
posttranscriptional regulation of gene expression	GO:0010608	166	0.015
negative regulation of neurogenesis	GO:0050768	4	0.014
cell type specific apoptotic process	GO:0097285	4	0.014
cell projection assembly	GO:0030031	35	0.014
positive regulation of protein transport	GO:0051222	4	0.014
immune response	GO:0006955	192	0.014
regulation of vulval development	GO:0040028	248	0.014
cellular component assembly involved in morphogenesis	GO:0010927	183	0.014
apoptotic cell clearance	GO:0043277	111	0.014
rna biosynthetic process	GO:0032774	169	0.014
single organism membrane organization	GO:0044802	35	0.014
purine nucleotide metabolic process	GO:0006163	95	0.013
positive regulation of nitrogen compound metabolic process	GO:0051173	134	0.013
tube development	GO:0035295	126	0.013	Mouse
response to mechanical stimulus	GO:0009612	28	0.013
positive regulation of hydrolase activity	GO:0051345	38	0.013
nucleoside phosphate catabolic process	GO:1901292	77	0.013
myosin filament organization	GO:0031033	138	0.013
negative regulation of post embryonic development	GO:0048581	208	0.013
cellular macromolecule catabolic process	GO:0044265	73	0.013
nucleobase containing compound catabolic process	GO:0034655	114	0.013
regulation of cellular amine metabolic process	GO:0033238	0	0.013
positive regulation of molecular function	GO:0044093	61	0.013
regulation of rna metabolic process	GO:0051252	173	0.013
centrosomal and pronuclear rotation	GO:0035047	6	0.013
nucleoside triphosphate metabolic process	GO:0009141	87	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	28	0.013
regulation of mitotic cell cycle	GO:0007346	76	0.013
phosphorylation	GO:0016310	116	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	72	0.012
regulation of neurogenesis	GO:0050767	40	0.012
mitotic nuclear envelope reassembly	GO:0007084	3	0.012
lamellipodium assembly	GO:0030032	2	0.012
rna processing	GO:0006396	34	0.012
establishment of protein localization to membrane	GO:0090150	3	0.012
muscle cell development	GO:0055001	158	0.012
regulation of mesoderm development	GO:2000380	2	0.012
negative regulation of developmental process	GO:0051093	227	0.012
myosin filament assembly	GO:0031034	138	0.012
organelle fission	GO:0048285	363	0.012
nucleoside monophosphate metabolic process	GO:0009123	46	0.012
regulation of vesicle mediated transport	GO:0060627	27	0.012
ribonucleotide metabolic process	GO:0009259	99	0.012
regulation of cell communication	GO:0010646	176	0.012
defecation rhythm	GO:0035882	3	0.012
protein polymerization	GO:0051258	26	0.011
cellular response to chemical stimulus	GO:0070887	129	0.011
regulation of nuclear division	GO:0051783	115	0.011
organelle fusion	GO:0048284	8	0.011
spermatogenesis	GO:0007283	41	0.011
phagocytosis	GO:0006909	115	0.011
regulation of apoptotic signaling pathway	GO:2001233	1	0.011
regulation of transcription from rna polymerase ii promoter	GO:0006357	145	0.011
protein modification by small protein conjugation	GO:0032446	31	0.011
glycosyl compound catabolic process	GO:1901658	79	0.011
regulation of nematode larval development	GO:0061062	260	0.011
neuron projection development	GO:0031175	187	0.011
meiotic cytokinesis	GO:0033206	15	0.011
regulation of cell development	GO:0060284	49	0.011
anion transport	GO:0006820	30	0.011
microtubule polymerization	GO:0046785	16	0.011
regulation of cellular protein metabolic process	GO:0032268	75	0.011
multi organism behavior	GO:0051705	389	0.010
negative regulation of cellular metabolic process	GO:0031324	95	0.010
rna dependent dna replication	GO:0006278	3	0.010
peptidyl threonine modification	GO:0018210	14	0.010
intracellular protein transport	GO:0006886	20	0.010
enzyme linked receptor protein signaling pathway	GO:0007167	50	0.010
attachment of spindle microtubules to kinetochore	GO:0008608	8	0.010
positive regulation of intracellular protein transport	GO:0090316	2	0.010
cytoplasmic transport	GO:0016482	23	0.010
negative regulation of mitotic cell cycle	GO:0045930	42	0.010
gtp metabolic process	GO:0046039	46	0.010

sqv-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.012

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