Caenorhabditis elegans

23 known processes

rpn-1 (CELE_T22D1.9)

Protein RPN-1

rpn-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pronuclear migrationGO:0035046510.823
reproductive system developmentGO:00614588500.804
cell cycle processGO:00224024820.684
Fly
cellular macromolecule biosynthetic processGO:00346452470.676
nucleobase containing compound biosynthetic processGO:00346541840.629
gonad developmentGO:00084068400.609
establishment of localization in cellGO:00516493180.600
negative regulation of vulval developmentGO:00400272060.597
cellular nitrogen compound biosynthetic processGO:00442711920.577
sex differentiationGO:00075489090.569
reproductive structure developmentGO:00486088500.563
macromolecule biosynthetic processGO:00090592500.549
locomotionGO:004001116340.541
single organism reproductive processGO:004470211960.537
receptor mediated endocytosisGO:00068987150.531
mitotic cell cycle processGO:19030471940.520
Fly
organic substance biosynthetic processGO:19015763230.513
cell cycleGO:00070495260.512
Fly
neuron projection morphogenesisGO:00488121140.494
genitalia developmentGO:00488067410.480
fertilizationGO:0009566630.473
single fertilizationGO:0007338610.471
determination of adult lifespanGO:00083408120.463
establishment of localizationGO:005123411710.462
organic cyclic compound biosynthetic processGO:19013621950.448
cellular biosynthetic processGO:00442493150.443
multicellular organism reproductionGO:00325048190.435
transcription dna templatedGO:00063511680.431
aromatic compound biosynthetic processGO:00194381920.422
post embryonic developmentGO:000979121520.420
development of primary sexual characteristicsGO:00451378400.398
embryo developmentGO:000979030520.395
organelle organizationGO:00069967830.395
Fly
meiotic cell cycle processGO:19030461700.381
neuron projection guidanceGO:0097485820.377
cellular localizationGO:00516413600.363
heterocycle biosynthetic processGO:00181301870.360
chromosome organizationGO:00512761040.355
rna biosynthetic processGO:00327741690.352
regulation of transcription dna templatedGO:00063551640.349
neuron developmentGO:00486661990.342
chemotaxisGO:00069351200.337
cell projection morphogenesisGO:00488581480.337
transportGO:000681010930.331
vesicle mediated transportGO:00161928520.330
embryo development ending in birth or egg hatchingGO:000979229920.330
mitotic spindle organizationGO:0007052810.325
Fly
cellular protein catabolic processGO:0044257370.315
axon guidanceGO:0007411820.302
gene expressionGO:00104674120.291
organelle fissionGO:00482853630.289
endocytosisGO:00068978190.289
cytoskeleton organizationGO:00070103390.284
Fly
negative regulation of nematode larval developmentGO:00610642080.279
translationGO:0006412370.278
regulation of transcription from rna polymerase ii promoterGO:00063571450.261
single organism cellular localizationGO:1902580720.259
single organism transportGO:00447654470.251
regulation of rna biosynthetic processGO:20011411650.248
biosynthetic processGO:00090583230.243
cell morphogenesis involved in neuron differentiationGO:00486671110.243
multicellular organismal reproductive processGO:00486098150.228
sexual reproductionGO:00199535460.227
organ developmentGO:004851311020.227
body morphogenesisGO:00101716200.218
generation of neuronsGO:00486992350.214
neuron projection developmentGO:00311751870.213
mitotic nuclear divisionGO:0007067890.212
cell part morphogenesisGO:00329901520.211
gamete generationGO:00072764610.210
regulation of nucleic acid templated transcriptionGO:19035061650.203
spindle organizationGO:0007051920.200
Fly
regulation of vulval developmentGO:00400282480.199
negative regulation of biological processGO:00485195670.195
multicellular organismal agingGO:00102598120.193
response to external stimulusGO:00096052890.187
agingGO:00075688120.185
regulation of multicellular organismal processGO:00512397260.184
cell morphogenesisGO:00009021630.179
centrosomal and pronuclear rotationGO:003504760.179
organelle disassemblyGO:190300820.171
nucleic acid metabolic processGO:00903042990.170
hermaphrodite genitalia developmentGO:00400357340.168
neuron differentiationGO:00301822170.164
developmental process involved in reproductionGO:000300611650.159
protein complex subunit organizationGO:00718222800.156
Fly
response to chemicalGO:00422213560.153
vulval developmentGO:00400253330.149
meiotic nuclear divisionGO:00071263000.147
taxisGO:00423301280.145
positive regulation of metabolic processGO:00098931870.143
axon developmentGO:00615641630.143
macromolecular complex subunit organizationGO:00439333200.143
Fly
nucleic acid templated transcriptionGO:00976591690.139
regulation of nematode larval developmentGO:00610622600.139
regulation of rna metabolic processGO:00512521730.139
organonitrogen compound metabolic processGO:19015641510.136
cell divisionGO:00513012620.134
glycosyl compound metabolic processGO:19016571000.133
organophosphate catabolic processGO:0046434810.132
purine ribonucleoside metabolic processGO:0046128920.128
nucleotide catabolic processGO:0009166770.125
nucleobase containing compound metabolic processGO:00061394060.124
regulation of gene expressionGO:00104683660.123
neurogenesisGO:00220082360.123
regulation of primary metabolic processGO:00800902920.122
positive regulation of cellular metabolic processGO:00313251780.122
modification dependent macromolecule catabolic processGO:0043632320.121
cell developmentGO:00484686960.120
cellular protein metabolic processGO:00442672790.118
posttranscriptional regulation of gene expressionGO:00106081660.117
protein localizationGO:00081042050.117
male gamete generationGO:0048232410.117
regulation of biosynthetic processGO:00098891890.116
regulation of nucleobase containing compound metabolic processGO:00192192220.116
regulation of nitrogen compound metabolic processGO:00511712220.115
negative regulation of metabolic processGO:00098922400.114
macromolecule catabolic processGO:00090572020.114
cell deathGO:00082195470.113
regulation of multicellular organismal developmentGO:20000263170.101
purine containing compound metabolic processGO:0072521950.100
multicellular organismal reproductive behaviorGO:00330573840.098
organic substance transportGO:00717021130.098
ovulationGO:0030728330.097
macromolecule localizationGO:00330367710.095
nuclear migrationGO:0007097540.095
negative regulation of developmental processGO:00510932270.094
cellular component assemblyGO:00226072930.093
single organism localizationGO:19025785180.089
oocyte axis specificationGO:000730920.089
chromatin organizationGO:0006325320.088
regulation of cell cycle processGO:00105641450.088
growthGO:00400075620.088
maintenance of locationGO:00512355800.086
purine ribonucleoside triphosphate catabolic processGO:0009207720.085
positive regulation of multicellular organismal processGO:00512404170.084
chromosome segregationGO:00070591800.084
regulation of post embryonic developmentGO:00485802600.084
cellular response to inorganic substanceGO:007124130.084
cellular macromolecule localizationGO:0070727750.083
cell projection organizationGO:00300302310.083
axonogenesisGO:00074091020.082
cell migrationGO:00164773060.081
positive regulation of macromolecule biosynthetic processGO:00105571090.081
regulation of cellular metabolic processGO:00313233050.081
establishment of organelle localizationGO:00516561230.079
protein metabolic processGO:00195384220.079
Fly
single organism organelle organizationGO:19025895010.078
Fly
lipid localizationGO:00108765730.078
head developmentGO:006032210.078
regulation of cellular biosynthetic processGO:00313261890.078
chromatin modificationGO:0016568320.075
positive regulation of cellular biosynthetic processGO:00313281090.075
regulation of macromolecule biosynthetic processGO:00105561890.075
regulation of growthGO:00400084090.074
multi organism reproductive processGO:00447038670.074
regulation of metabolic processGO:00192224780.074
positive regulation of developmental growthGO:00486393540.073
regulation of cellular component organizationGO:00511282480.073
reproductive behaviorGO:00190983870.073
regulation of macromolecule metabolic processGO:00602554210.072
regulation of biological qualityGO:00650087410.072
regulation of cytoplasmic transportGO:190364930.072
ovipositionGO:00189913640.072
establishment of nucleus localizationGO:0040023550.072
positive regulation of nitrogen compound metabolic processGO:00511731340.071
lipid storageGO:00199155650.071
protein modification processGO:00362112070.070
intracellular transportGO:0046907770.069
oocyte constructionGO:000730820.069
negative regulation of post embryonic developmentGO:00485812080.069
regulation of developmental processGO:00507936840.068
cellular protein localizationGO:0034613750.068
proteolysis involved in cellular protein catabolic processGO:0051603320.068
positive regulation of catalytic activityGO:0043085590.067
nucleoside phosphate catabolic processGO:1901292770.066
protein catabolic processGO:00301631620.066
proteasome assemblyGO:004324810.065
purine nucleoside metabolic processGO:0042278920.064
protein importGO:001703890.064
meiotic cell cycleGO:00513213350.063
cellular component movementGO:00069283880.062
phosphorus metabolic processGO:00067932320.061
positive regulation of developmental processGO:00510944080.061
positive regulation of multicellular organism growthGO:00400183520.060
negative regulation of macromolecule metabolic processGO:00106052290.060
cellular response to stressGO:00335541620.059
regulation of cell cycleGO:00517261940.058
maintenance of protein locationGO:0045185150.058
cellular response to dna damage stimulusGO:0006974410.057
cellular process involved in reproduction in multicellular organismGO:00224123510.057
negative regulation of multicellular organismal processGO:00512412360.057
female gamete generationGO:00072922540.055
positive regulation of rna metabolic processGO:00512541030.055
mitotic sister chromatid segregationGO:0000070380.054
protein complex assemblyGO:00064611860.054
small molecule metabolic processGO:00442811860.054
organonitrogen compound biosynthetic processGO:1901566440.053
covalent chromatin modificationGO:0016569300.053
multi organism behaviorGO:00517053890.053
proteasomal protein catabolic processGO:0010498200.053
regulation of cellular localizationGO:0060341420.052
positive regulation of growthGO:00459273690.051
regulation of chromosome organizationGO:0033044200.051
behaviorGO:00076105270.051
carbohydrate derivative metabolic processGO:19011351410.051
regulation of gene expression epigeneticGO:00400291630.050
heterocycle catabolic processGO:00467001190.049
developmental growthGO:00485894120.049
positive regulation of intracellular transportGO:003238820.049
oogenesisGO:00484772290.048
cellular component morphogenesisGO:00329893180.048
purine ribonucleoside triphosphate metabolic processGO:0009205870.047
nucleotide metabolic processGO:00091171080.047
er associated misfolded protein catabolic processGO:007171240.047
positive regulation of molecular functionGO:0044093610.047
organelle localizationGO:00516401270.046
regulation of nucleocytoplasmic transportGO:004682230.045
ribose phosphate metabolic processGO:0019693990.045
posttranscriptional gene silencing by rnaGO:00351941430.044
nucleus localizationGO:0051647550.044
single organism carbohydrate metabolic processGO:0044723290.044
regulation of developmental growthGO:00486383890.044
rna metabolic processGO:00160702280.044
nucleoside triphosphate catabolic processGO:0009143720.044
positive regulation of cellular catabolic processGO:0031331350.043
nucleoside catabolic processGO:0009164780.043
transcription from rna polymerase ii promoterGO:00063661490.042
spermatogenesisGO:0007283410.042
regulation of translationGO:0006417190.042
cellular response to metal ionGO:007124830.042
deathGO:00162655470.042
purine nucleoside catabolic processGO:0006152750.041
regulation of cellular macromolecule biosynthetic processGO:20001121880.041
multicellular organism growthGO:00352643850.041
ribonucleoside metabolic processGO:0009119980.040
nucleoside monophosphate metabolic processGO:0009123460.040
response to nutrient levelsGO:0031667350.040
intracellular protein transmembrane transportGO:006500240.040
collagen and cuticulin based cuticle developmentGO:0040002990.040
cell motilityGO:00488703130.040
ribonucleoprotein complex assemblyGO:002261840.039
establishment of protein localization to membraneGO:009015030.039
ribonucleotide catabolic processGO:0009261750.039
ribonucleoside triphosphate metabolic processGO:0009199870.039
macromolecular complex assemblyGO:00650031930.039
response to heatGO:0009408500.038
sister chromatid segregationGO:0000819460.038
cuticle developmentGO:00423351000.038
regulation of catalytic activityGO:0050790780.038
secretion by cellGO:00329401380.038
single organism catabolic processGO:00447121290.038
organic acid metabolic processGO:0006082470.036
cell type specific apoptotic processGO:009728540.036
organic cyclic compound catabolic processGO:19013611190.036
regulation of localizationGO:00328791940.035
ubiquitin dependent protein catabolic processGO:0006511320.035
positive regulation of chromosome organizationGO:200125220.035
aromatic compound catabolic processGO:00194391160.035
single organism biosynthetic processGO:0044711910.035
regulation of multicellular organism growthGO:00400143730.035
rna interferenceGO:00162461370.035
purine nucleoside monophosphate catabolic processGO:0009128280.035
phosphate containing compound metabolic processGO:00067962320.035
negative regulation of gene expressionGO:00106292170.035
organonitrogen compound catabolic processGO:1901565900.034
dna templated transcription elongationGO:000635410.034
pole plasm assemblyGO:000731520.034
protein glycosylationGO:0006486170.034
protein localization to nucleusGO:0034504110.034
positive regulation of macromolecule metabolic processGO:00106041490.033
cellular nitrogen compound catabolic processGO:00442701190.033
protein transmembrane transportGO:007180640.033
oxoacid metabolic processGO:0043436470.032
purine nucleoside triphosphate metabolic processGO:0009144870.032
nucleoside metabolic processGO:0009116990.032
regulation of molecular functionGO:0065009890.032
germ cell developmentGO:00072813510.032
cell surface receptor signaling pathwayGO:00071661490.032
positive regulation of cellular protein catabolic processGO:190336430.032
multi multicellular organism processGO:00447063900.032
protein targeting to mitochondrionGO:000662620.032
purine containing compound catabolic processGO:0072523750.031
cellular amino acid metabolic processGO:0006520150.031
posttranscriptional gene silencingGO:00164411430.031
positive regulation of rna biosynthetic processGO:19026801020.031
gene silencing by rnaGO:00310471430.031
single organism intracellular transportGO:1902582700.031
response to abiotic stimulusGO:00096281520.031
multi organism reproductive behaviorGO:00447053870.030
cofactor metabolic processGO:005118690.030
cell morphogenesis involved in differentiationGO:00009041120.030
purine ribonucleoside catabolic processGO:0046130750.030
cellular protein complex assemblyGO:00436231780.030
modification dependent protein catabolic processGO:0019941320.029
carboxylic acid metabolic processGO:0019752340.029
glycosyl compound catabolic processGO:1901658790.029
purine nucleoside triphosphate catabolic processGO:0009146720.029
atp metabolic processGO:0046034420.029
maintenance of protein location in cellGO:0032507120.028
regenerationGO:003109940.028
programmed cell deathGO:00125015000.028
ribonucleoside monophosphate metabolic processGO:0009161450.028
positive regulation of hydrolase activityGO:0051345380.027
meiotic chromosome segregationGO:00451321390.027
macromolecule modificationGO:00434122180.027
positive regulation of biosynthetic processGO:00098911090.027
apoptotic processGO:00069154780.027
regulation of cell divisionGO:00513021420.027
regulation of nuclear divisionGO:00517831150.027
cellular component biogenesisGO:00440852970.027
catabolic processGO:00090563180.027
regulation of organelle organizationGO:00330431640.027
response to woundingGO:000961140.026
cell cycle phase transitionGO:0044770190.026
cellular catabolic processGO:00442481990.026
positive regulation of transcription dna templatedGO:00458931020.026
ribonucleoside triphosphate catabolic processGO:0009203720.026
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.025
carbohydrate derivative catabolic processGO:1901136820.025
regulation of sequence specific dna binding transcription factor activityGO:005109030.025
maintenance of location in cellGO:0051651120.025
positive regulation of nucleic acid templated transcriptionGO:19035081020.025
purine nucleotide catabolic processGO:0006195750.025
protein modification by small protein conjugation or removalGO:0070647400.024
cellular protein modification processGO:00064642070.024
organic substance catabolic processGO:19015752940.024
protein targetingGO:0006605100.024
protein localization to mitochondrionGO:007058520.024
nucleoside phosphate metabolic processGO:00067531080.024
regulation of protein localizationGO:0032880500.024
proteolysisGO:0006508610.024
Fly
translational initiationGO:000641320.024
regulation of mitosisGO:0007088180.024
positive regulation of gene expressionGO:00106281120.024
glycosylationGO:0070085200.024
secretionGO:00469031470.024
organelle assemblyGO:00709252140.023
purine ribonucleotide metabolic processGO:0009150950.023
cellular macromolecular complex assemblyGO:00346221840.023
rrna metabolic processGO:001607230.023
negative regulation of cellular metabolic processGO:0031324950.022
carbohydrate derivative biosynthetic processGO:1901137460.022
positive regulation of protein transportGO:005122240.022
gene silencingGO:00164581430.022
positive regulation of proteasomal protein catabolic processGO:190180010.022
histone modificationGO:0016570300.022
macromolecule glycosylationGO:0043413180.021
single organism nuclear importGO:190259360.021
protein targeting to membraneGO:000661210.021
protein complex biogenesisGO:00702711860.021
nucleoside triphosphate metabolic processGO:0009141870.021
positive regulation of phosphate metabolic processGO:0045937560.021
muscle cell differentiationGO:00426921710.021
nervous system developmentGO:00073992530.021
regulation of protein import into nucleusGO:004230630.020
regulation of protein targetingGO:190353330.020
immune responseGO:00069551920.020
response to external biotic stimulusGO:00432071010.020
small molecule biosynthetic processGO:0044283380.020
positive regulation of proteolysis involved in cellular protein catabolic processGO:190305210.020
golgi vesicle transportGO:004819330.020
defense responseGO:00069522960.020
defense response to gram negative bacteriumGO:0050829640.019
muscle tissue developmentGO:006053710.019
autophagyGO:0006914290.019
rna catabolic processGO:0006401210.019
positive regulation of intracellular protein transportGO:009031620.019
digestive tract morphogenesisGO:0048546760.019
regulation of phosphorus metabolic processGO:0051174810.019
protein localization to organelleGO:0033365370.019
signal transductionGO:00071653170.019
regulation of ras protein signal transductionGO:0046578410.018
negative regulation of nitrogen compound metabolic processGO:0051172630.018
purine nucleotide metabolic processGO:0006163950.018
protein import into nucleusGO:000660660.018
atp catabolic processGO:0006200270.018
positive regulation of catabolic processGO:0009896380.018
negative regulation of lipid storageGO:001088810.018
purine nucleoside monophosphate metabolic processGO:0009126430.018
system processGO:00030081360.017
metaphase anaphase transition of mitotic cell cycleGO:0007091100.017
establishment of rna localizationGO:005123630.017
microtubule based processGO:00070171820.017
Fly
positive regulation of protein metabolic processGO:0051247450.017
meiosis iGO:0007127190.017
regulation of cell deathGO:0010941650.017
regulation of chromosome segregationGO:0051983200.017
negative regulation of cellular processGO:00485232390.017
neuron recognitionGO:0008038830.017
establishment of mitotic spindle orientationGO:0000132280.017
cellular macromolecule catabolic processGO:0044265730.017
inductive cell migrationGO:00400391450.017
regulation of meiotic cell cycleGO:00514451360.017
gastrulationGO:0007369580.017
localization of cellGO:00516743130.017
protein oligomerizationGO:005125940.016
rna localizationGO:000640330.016
positive regulation of cellular component organizationGO:0051130340.016
positive regulation of protein catabolic processGO:004573260.016
misfolded or incompletely synthesized protein catabolic processGO:000651540.016
carbohydrate biosynthetic processGO:001605140.016
nucleobase containing small molecule metabolic processGO:00550861150.016
establishment of spindle localizationGO:0051293510.016
cytoplasmic transportGO:0016482230.016
regulation of cellular protein metabolic processGO:0032268750.016
organism emergence from protective structureGO:0071684480.016
molting cycleGO:00423032810.016
regulation of phosphate metabolic processGO:0019220810.016
cytokinesisGO:0000910800.015
oocyte differentiationGO:0009994450.015
regulation of protein metabolic processGO:0051246810.015
regulation of mitotic cell cycleGO:0007346760.015
single organism signalingGO:00447004010.015
ribonucleoside monophosphate catabolic processGO:0009158280.015
establishment of protein localization to organelleGO:007259490.015
negative regulation of neurogenesisGO:005076840.015
anatomical structure formation involved in morphogenesisGO:00486462500.014
glycosaminoglycan metabolic processGO:003020360.014
attachment of mitotic spindle microtubules to kinetochoreGO:005131560.014
regulation of chromatin modificationGO:190330820.014
nucleic acid transportGO:005065730.014
actin filament based processGO:00300291910.014
coenzyme metabolic processGO:000673290.014
establishment of protein localizationGO:0045184500.014
response to topologically incorrect proteinGO:0035966820.014
regulation of transferase activityGO:0051338310.014
myosin filament assemblyGO:00310341380.014
regulation of purine nucleotide catabolic processGO:0033121350.014
chromatin remodelingGO:000633820.014
g1 s transition of mitotic cell cycleGO:000008220.014
mitotic sister chromatid separationGO:0051306130.014
carbohydrate metabolic processGO:0005975340.014
purine ribonucleotide catabolic processGO:0009154750.013
muscle structure developmentGO:00610611910.013
positive regulation of nucleobase containing compound metabolic processGO:00459351340.013
regulation of cell differentiationGO:0045595810.013
establishment of mitotic spindle localizationGO:0040001410.013
transcription elongation from rna polymerase ii promoterGO:000636810.013
dna metabolic processGO:0006259740.013
regulation of mitotic sister chromatid segregationGO:0033047160.013
ribonucleotide metabolic processGO:0009259990.013
regulation of cellular component biogenesisGO:0044087260.013
establishment of spindle orientationGO:0051294340.012
defense response to other organismGO:00985421000.012
regulation of response to stimulusGO:00485832430.012
ribonucleoside catabolic processGO:0042454770.012
intracellular protein transmembrane importGO:004474330.012
regulation of protein ubiquitinationGO:003139630.012
neurological system processGO:0050877530.012
regulation of phosphorylationGO:0042325450.012
purine ribonucleoside monophosphate catabolic processGO:0009169280.012
positive regulation of phosphorus metabolic processGO:0010562560.012
signalingGO:00230524010.012
response to inorganic substanceGO:0010035500.012
ras protein signal transductionGO:0007265310.011
nucleobase containing compound catabolic processGO:00346551140.011
dna repairGO:0006281230.011
regulation of cellular amine metabolic processGO:003323800.011
dna templated transcription initiationGO:000635230.011
nuclear importGO:005117080.011
transcription initiation from rna polymerase ii promoterGO:000636720.011
positive regulation of protein modification processGO:0031401290.011
rna transportGO:005065830.011
guanosine containing compound catabolic processGO:1901069480.011
cellular amine metabolic processGO:0044106150.011
cell proliferationGO:00082831160.011
Fly
epidermal cell fate specificationGO:000995750.011
establishment or maintenance of cell polarityGO:0007163630.011
regulation of apoptotic processGO:0042981360.011
organophosphate metabolic processGO:00196371250.011
regulation of response to woundingGO:190303410.011
regulation of catabolic processGO:0009894570.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145100.011
regulation of cell proliferationGO:00421271050.011
regulation of protein localization to nucleusGO:190018050.011
neuron apoptotic processGO:005140240.011
cytoskeleton dependent cytokinesisGO:0061640350.010
positive regulation of neuron projection developmentGO:001097640.010
regulation of small gtpase mediated signal transductionGO:0051056410.010
regulation of intracellular signal transductionGO:1902531770.010
striated muscle cell differentiationGO:00511461580.010
positive regulation of protein localization to nucleusGO:190018220.010
protein transportGO:0015031450.010
regulation of hydrolase activityGO:0051336450.010
nitrogen compound transportGO:0071705490.010

rpn-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
motor neuron diseaseDOID:23100.028
central nervous system diseaseDOID:33100.028
amyotrophic lateral sclerosisDOID:33200.028
nervous system diseaseDOID:86300.028
neurodegenerative diseaseDOID:128900.028
disease of metabolismDOID:001466700.021