Caenorhabditis elegans

73 known processes

pdi-2 (CELE_C07A12.4)

Protein PDI-2

pdi-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979121520.773
response to topologically incorrect proteinGO:0035966820.701
establishment of localizationGO:005123411710.680
embryo development ending in birth or egg hatchingGO:000979229920.635
organ developmentGO:004851311020.606
reproductive structure developmentGO:00486088500.530
locomotionGO:004001116340.524
embryo developmentGO:000979030520.492
vesicle mediated transportGO:00161928520.480
response to unfolded proteinGO:0006986710.472
genitalia developmentGO:00488067410.436
molting cycle collagen and cuticulin based cuticleGO:00189962810.430
signalingGO:00230524010.374
cellular component movementGO:00069283880.336
developmental process involved in reproductionGO:000300611650.324
response to endoplasmic reticulum stressGO:0034976710.320
receptor mediated endocytosisGO:00068987150.308
cellular response to topologically incorrect proteinGO:0035967760.300
endoplasmic reticulum unfolded protein responseGO:0030968660.293
reproductive system developmentGO:00614588500.285
deathGO:00162655470.272
Human
endocytosisGO:00068978190.270
sexual reproductionGO:00199535460.264
er nucleus signaling pathwayGO:0006984660.256
hermaphrodite genitalia developmentGO:00400357340.253
meiotic cell cycleGO:00513213350.251
cellular localizationGO:00516413600.250
multi organism reproductive processGO:00447038670.245
cell migrationGO:00164773060.233
cellular protein metabolic processGO:00442672790.221
sex differentiationGO:00075489090.219
positive regulation of multicellular organismal processGO:00512404170.210
regulation of metabolic processGO:00192224780.200
single organism reproductive processGO:004470211960.188
protein metabolic processGO:00195384220.186
gonad developmentGO:00084068400.185
cellular response to unfolded proteinGO:0034620710.181
localization of cellGO:00516743130.176
cell motilityGO:00488703130.175
development of primary sexual characteristicsGO:00451378400.167
embryonic body morphogenesisGO:0010172490.167
developmental growthGO:00485894120.152
protein localization to endoplasmic reticulumGO:007097220.150
positive regulation of cellular processGO:00485223320.138
organic substance biosynthetic processGO:19015763230.138
agingGO:00075688120.133
organelle organizationGO:00069967830.132
establishment of localization in cellGO:00516493180.129
positive regulation of developmental processGO:00510944080.128
germ cell developmentGO:00072813510.122
multicellular organismal agingGO:00102598120.120
macromolecule localizationGO:00330367710.119
cell cycleGO:00070495260.115
multicellular organism reproductionGO:00325048190.114
signal transductionGO:00071653170.114
regulation of multicellular organismal processGO:00512397260.112
regulation of biological qualityGO:00650087410.108
meiotic nuclear divisionGO:00071263000.106
positive regulation of multicellular organism growthGO:00400183520.105
chemotaxisGO:00069351200.105
protein localizationGO:00081042050.104
determination of adult lifespanGO:00083408120.103
axonogenesisGO:00074091020.102
gamete generationGO:00072764610.102
macromolecular complex subunit organizationGO:00439333200.101
cellular component assemblyGO:00226072930.101
cellular component morphogenesisGO:00329893180.100
negative regulation of cellular processGO:00485232390.099
inductive cell migrationGO:00400391450.099
negative regulation of vulval developmentGO:00400272060.099
molting cycleGO:00423032810.097
multicellular organismal reproductive processGO:00486098150.096
negative regulation of nematode larval developmentGO:00610642080.093
biosynthetic processGO:00090583230.092
regulation of cellular metabolic processGO:00313233050.087
cellular biosynthetic processGO:00442493150.085
embryonic morphogenesisGO:00485981520.085
single organism signalingGO:00447004010.084
cell surface receptor signaling pathwayGO:00071661490.083
cellular response to chemical stimulusGO:00708871290.081
positive regulation of developmental growthGO:00486393540.081
body morphogenesisGO:00101716200.077
protein modification processGO:00362112070.077
multicellular organismal reproductive behaviorGO:00330573840.076
regulation of developmental growthGO:00486383890.076
epithelial tube morphogenesisGO:006056210.076
negative regulation of biological processGO:00485195670.075
regulation of multicellular organism growthGO:00400143730.071
maintenance of locationGO:00512355800.070
negative regulation of developmental processGO:00510932270.070
gene expressionGO:00104674120.070
tube developmentGO:00352951260.070
response to chemicalGO:00422213560.069
transportGO:000681010930.069
single organism transportGO:00447654470.069
tube morphogenesisGO:0035239790.068
cell morphogenesisGO:00009021630.067
multi multicellular organism processGO:00447063900.067
lipid storageGO:00199155650.065
lipid localizationGO:00108765730.065
nervous system developmentGO:00073992530.065
cellular protein modification processGO:00064642070.064
regulation of macromolecule metabolic processGO:00602554210.063
cell developmentGO:00484686960.062
regulation of vulval developmentGO:00400282480.062
macromolecule biosynthetic processGO:00090592500.061
cell deathGO:00082195470.060
Human
regulation of primary metabolic processGO:00800902920.057
regulation of cellular component organizationGO:00511282480.056
regulation of developmental processGO:00507936840.055
positive regulation of growthGO:00459273690.055
cellular process involved in reproduction in multicellular organismGO:00224123510.055
multicellular organism growthGO:00352643850.055
phosphorus metabolic processGO:00067932320.054
regulation of growthGO:00400084090.053
cellular component biogenesisGO:00440852970.053
tissue developmentGO:00098881120.052
regulation of phosphorus metabolic processGO:0051174810.051
multi organism behaviorGO:00517053890.051
growthGO:00400075620.051
head developmentGO:006032210.050
macromolecule modificationGO:00434122180.049
intracellular protein transmembrane transportGO:006500240.048
catabolic processGO:00090563180.048
taxisGO:00423301280.046
meiotic cell cycle processGO:19030461700.046
vulval developmentGO:00400253330.045
regulation of cell communicationGO:00106461760.044
Human
female gamete generationGO:00072922540.043
establishment of protein localization to membraneGO:009015030.043
regulation of nematode larval developmentGO:00610622600.043
cellular component assembly involved in morphogenesisGO:00109271830.043
cellular response to stressGO:00335541620.042
cell cycle processGO:00224024820.042
nucleobase containing compound metabolic processGO:00061394060.042
regulation of molecular functionGO:0065009890.042
positive regulation of cell migrationGO:003033530.042
response to organic substanceGO:00100331310.041
organelle fissionGO:00482853630.041
regulation of post embryonic developmentGO:00485802600.041
regulation of response to stimulusGO:00485832430.040
Human
organonitrogen compound metabolic processGO:19015641510.040
organ morphogenesisGO:0009887670.039
neuron developmentGO:00486661990.039
oogenesisGO:00484772290.039
positive regulation of metabolic processGO:00098931870.039
ovipositionGO:00189913640.038
regulation of phosphate metabolic processGO:0019220810.038
cellular nitrogen compound biosynthetic processGO:00442711920.038
regulation of gene expressionGO:00104683660.037
positive regulation of macromolecule metabolic processGO:00106041490.037
system processGO:00030081360.037
organic cyclic compound catabolic processGO:19013611190.036
nucleobase containing small molecule metabolic processGO:00550861150.036
positive regulation of cellular metabolic processGO:00313251780.036
multi organism reproductive behaviorGO:00447053870.036
cell substrate adhesionGO:003158910.036
neuron projection guidanceGO:0097485820.036
cellular catabolic processGO:00442481990.036
actin cytoskeleton organizationGO:00300361840.035
cellular response to organic substanceGO:00713101190.033
single organism biosynthetic processGO:0044711910.033
reproductive behaviorGO:00190983870.033
single organism organelle organizationGO:19025895010.033
regulation of locomotionGO:00400121610.033
single organism localizationGO:19025785180.032
neurogenesisGO:00220082360.032
macromolecule catabolic processGO:00090572020.031
cell projection organizationGO:00300302310.030
regulation of multicellular organismal developmentGO:20000263170.030
sensory organ morphogenesisGO:009059620.029
positive regulation of nitrogen compound metabolic processGO:00511731340.029
regulation of catalytic activityGO:0050790780.029
organophosphate metabolic processGO:00196371250.028
ovulationGO:0030728330.028
macromolecular complex assemblyGO:00650031930.028
behaviorGO:00076105270.028
cell morphogenesis involved in differentiationGO:00009041120.028
small molecule metabolic processGO:00442811860.028
membrane organizationGO:00610241350.027
generation of neuronsGO:00486992350.027
negative regulation of post embryonic developmentGO:00485812080.027
phosphate containing compound metabolic processGO:00067962320.027
regulation of signalingGO:00230511720.026
Human
positive regulation of biosynthetic processGO:00098911090.026
regulation of cellular protein metabolic processGO:0032268750.026
glycosyl compound metabolic processGO:19016571000.026
posttranscriptional regulation of gene expressionGO:00106081660.026
neuron differentiationGO:00301822170.025
organophosphate catabolic processGO:0046434810.025
cellular macromolecule biosynthetic processGO:00346452470.025
regulation of biosynthetic processGO:00098891890.025
negative regulation of multicellular organismal processGO:00512412360.025
regulation of signal transductionGO:00099661350.024
Human
secretionGO:00469031470.024
organelle assemblyGO:00709252140.024
axon guidanceGO:0007411820.024
negative regulation of gene expressionGO:00106292170.023
positive regulation of locomotionGO:0040017420.023
cell projection morphogenesisGO:00488581480.023
regulation of nucleobase containing compound metabolic processGO:00192192220.023
intracellular transportGO:0046907770.022
digestive tract morphogenesisGO:0048546760.022
actin filament based processGO:00300291910.022
regulation of translationGO:0006417190.022
maintenance of protein locationGO:0045185150.022
positive regulation of macromolecule biosynthetic processGO:00105571090.022
axon developmentGO:00615641630.022
protein transmembrane transportGO:007180640.022
defense responseGO:00069522960.022
single organism intracellular transportGO:1902582700.022
response to external stimulusGO:00096052890.022
oxidation reduction processGO:0055114590.021
protein targeting to membraneGO:000661210.021
enzyme linked receptor protein signaling pathwayGO:0007167500.021
epithelium developmentGO:0060429680.021
protein phosphorylationGO:0006468850.021
apoptotic processGO:00069154780.021
Human
cellular protein localizationGO:0034613750.021
negative regulation of metabolic processGO:00098922400.020
regulation of cell proliferationGO:00421271050.020
cytoskeleton organizationGO:00070103390.020
muscle cell differentiationGO:00426921710.020
positive regulation of cellular biosynthetic processGO:00313281090.020
regulation of anatomical structure morphogenesisGO:0022603510.020
phagocytosisGO:00069091150.020
response to abiotic stimulusGO:00096281520.019
Human
regulation of protein metabolic processGO:0051246810.019
regulation of localizationGO:00328791940.019
aromatic compound catabolic processGO:00194391160.019
protein catabolic processGO:00301631620.019
programmed cell deathGO:00125015000.019
Human
organic substance catabolic processGO:19015752940.019
positive regulation of cysteine type endopeptidase activityGO:200105630.018
cell part morphogenesisGO:00329901520.018
purine nucleoside metabolic processGO:0042278920.018
lipid metabolic processGO:0006629770.018
cellular macromolecule catabolic processGO:0044265730.018
digestive tract developmentGO:00485651220.018
striated muscle myosin thick filament assemblyGO:00716881380.017
purine ribonucleoside triphosphate metabolic processGO:0009205870.017
microvillus assemblyGO:003003310.017
response to growth factorGO:0070848180.017
positive regulation of nucleotide metabolic processGO:0045981280.017
regulation of cell motilityGO:2000145570.017
negative regulation of cellular metabolic processGO:0031324950.017
myofibril assemblyGO:00302391540.017
purine nucleoside triphosphate metabolic processGO:0009144870.016
myosin filament assemblyGO:00310341380.016
skeletal muscle organ developmentGO:006053830.016
positive regulation of catalytic activityGO:0043085590.016
protein complex biogenesisGO:00702711860.016
myosin filament organizationGO:00310331380.016
male sex differentiationGO:0046661860.016
cuticle developmentGO:00423351000.015
translational elongationGO:000641410.015
positive regulation of hydrolase activityGO:0051345380.015
cellular macromolecule localizationGO:0070727750.015
cellular protein catabolic processGO:0044257370.015
phosphorylationGO:00163101160.015
regulation of organ morphogenesisGO:200002740.015
pigmentationGO:004347320.015
regulation of cell cycleGO:00517261940.015
nucleobase containing compound biosynthetic processGO:00346541840.015
nucleic acid metabolic processGO:00903042990.015
anatomical structure formation involved in morphogenesisGO:00486462500.014
protein transportGO:0015031450.014
negative regulation of cell communicationGO:0010648610.014
synaptic transmissionGO:00072681060.014
protein complex subunit organizationGO:00718222800.014
regulation of cell migrationGO:0030334550.014
muscle structure developmentGO:00610611910.014
rna biosynthetic processGO:00327741690.014
proteolysisGO:0006508610.014
regulation of nitrogen compound metabolic processGO:00511712220.014
tissue morphogenesisGO:0048729650.014
regulation of small gtpase mediated signal transductionGO:0051056410.014
positive regulation of gene expressionGO:00106281120.014
calcium mediated signalingGO:001972230.014
cell proliferationGO:00082831160.014
male anatomical structure morphogenesisGO:0090598780.013
post embryonic organ developmentGO:00485693360.013
regulation of cell differentiationGO:0045595810.013
regulation of rna metabolic processGO:00512521730.013
response to external biotic stimulusGO:00432071010.013
cellular protein complex assemblyGO:00436231780.013
modification dependent protein catabolic processGO:0019941320.013
purine containing compound metabolic processGO:0072521950.013
microtubule based processGO:00070171820.013
synaptic growth at neuromuscular junctionGO:005112410.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178160.013
detection of external stimulusGO:000958140.013
regulation of intracellular signal transductionGO:1902531770.013
Human
rna metabolic processGO:00160702280.013
muscle tissue developmentGO:006053710.012
positive regulation of protein transportGO:005122240.012
ubiquitin dependent protein catabolic processGO:0006511320.012
negative regulation of macromolecule metabolic processGO:00106052290.012
epithelial cell proliferationGO:005067310.012
ribonucleoside triphosphate catabolic processGO:0009203720.012
positive regulation of phosphate metabolic processGO:0045937560.012
cell morphogenesis involved in neuron differentiationGO:00486671110.012
cell divisionGO:00513012620.012
cellular amino acid metabolic processGO:0006520150.012
establishment of protein localizationGO:0045184500.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.011
organic substance transportGO:00717021130.011
chromosome segregationGO:00070591800.011
protein complex assemblyGO:00064611860.011
positive regulation of nucleobase containing compound metabolic processGO:00459351340.011
regulation of macromolecule biosynthetic processGO:00105561890.011
neuron projection morphogenesisGO:00488121140.011
nucleoside metabolic processGO:0009116990.011
protein localization to organelleGO:0033365370.011
adult locomotory behaviorGO:000834410.011
collagen and cuticulin based cuticle developmentGO:0040002990.011
establishment of organelle localizationGO:00516561230.011
organonitrogen compound catabolic processGO:1901565900.011
positive regulation of molecular functionGO:0044093610.011
carbohydrate derivative metabolic processGO:19011351410.011
posttranscriptional gene silencing by rnaGO:00351941430.011
maintenance of protein location in cellGO:0032507120.011
digestive system developmentGO:00551231220.010
skeletal muscle thin filament assemblyGO:003024030.010
positive regulation of phosphorus metabolic processGO:0010562560.010
regulation of hydrolase activityGO:0051336450.010
negative regulation of biosynthetic processGO:0009890650.010
cytosolic calcium ion homeostasisGO:005148020.010
rna localizationGO:000640330.010
meiotic chromosome segregationGO:00451321390.010
protein targetingGO:0006605100.010
single organism catabolic processGO:00447121290.010
negative regulation of nucleic acid templated transcriptionGO:1903507530.010
actomyosin structure organizationGO:00310321540.010

pdi-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
myopathyDOID:42300.035
heart diseaseDOID:11400.035
muscle tissue diseaseDOID:6600.035
muscular diseaseDOID:008000000.035
cardiomyopathyDOID:005070000.035
cardiovascular system diseaseDOID:128700.035
musculoskeletal system diseaseDOID:1700.035
disease of anatomical entityDOID:700.035
dilated cardiomyopathyDOID:1293000.016
intrinsic cardiomyopathyDOID:006003600.016