Caenorhabditis elegans

82 known processes

cul-1 (CELE_D2045.6)

Protein CUL-1

cul-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.954
embryo developmentGO:000979030520.912
locomotionGO:004001116340.866
reproductive system developmentGO:00614588500.854
genitalia developmentGO:00488067410.826
meiotic nuclear divisionGO:00071263000.809
cell cycle processGO:00224024820.767
gonad developmentGO:00084068400.750
organ developmentGO:004851311020.717
organelle organizationGO:00069967830.698
sex differentiationGO:00075489090.691
developmental process involved in reproductionGO:000300611650.682
receptor mediated endocytosisGO:00068987150.659
nucleobase containing compound metabolic processGO:00061394060.658
post embryonic developmentGO:000979121520.649
hermaphrodite genitalia developmentGO:00400357340.634
development of primary sexual characteristicsGO:00451378400.606
reproductive structure developmentGO:00486088500.593
gene expressionGO:00104674120.580
vesicle mediated transportGO:00161928520.577
meiotic cell cycleGO:00513213350.568
modification dependent protein catabolic processGO:0019941320.484
Human Yeast Mouse
germ cell developmentGO:00072813510.452
cellular protein catabolic processGO:0044257370.446
Human Yeast Mouse
regulation of meiotic cell cycleGO:00514451360.445
cell cycleGO:00070495260.421
regulation of cell cycle processGO:00105641450.409
Fly
rna biosynthetic processGO:00327741690.391
cell developmentGO:00484686960.382
Fly
cellular nitrogen compound biosynthetic processGO:00442711920.373
spindle organizationGO:0007051920.370
rna metabolic processGO:00160702280.362
mitotic nuclear divisionGO:0007067890.360
negative regulation of biological processGO:00485195670.345
proteolysis involved in cellular protein catabolic processGO:0051603320.336
Human Yeast Mouse
single organism reproductive processGO:004470211960.323
endocytosisGO:00068978190.317
apoptotic processGO:00069154780.315
organelle fissionGO:00482853630.310
modification dependent macromolecule catabolic processGO:0043632320.307
Human Yeast Mouse
single organism organelle organizationGO:19025895010.297
regulation of primary metabolic processGO:00800902920.294
multicellular organismal reproductive processGO:00486098150.293
nucleobase containing compound biosynthetic processGO:00346541840.292
determination of adult lifespanGO:00083408120.284
positive regulation of cellular processGO:00485223320.279
regulation of nucleic acid templated transcriptionGO:19035061650.271
mrna metabolic processGO:0016071310.264
transportGO:000681010930.260
regulation of developmental processGO:00507936840.251
cellular process involved in reproduction in multicellular organismGO:00224123510.249
cellular catabolic processGO:00442481990.245
Human Yeast Mouse
regulation of cellular component organizationGO:00511282480.239
meiotic cell cycle processGO:19030461700.237
mitotic cell cycle processGO:19030471940.236
heterocycle biosynthetic processGO:00181301870.235
nervous system developmentGO:00073992530.231
Fly
cell deathGO:00082195470.230
agingGO:00075688120.229
body morphogenesisGO:00101716200.225
regulation of nucleobase containing compound metabolic processGO:00192192220.223
response to external stimulusGO:00096052890.219
Worm
chromosome organizationGO:00512761040.218
deathGO:00162655470.207
positive regulation of multicellular organismal processGO:00512404170.207
regulation of cellular metabolic processGO:00313233050.205
cellular component assemblyGO:00226072930.204
regulation of organelle organizationGO:00330431640.203
chromosome segregationGO:00070591800.203
growthGO:00400075620.201
Worm
gamete generationGO:00072764610.200
nucleic acid metabolic processGO:00903042990.198
neurogenesisGO:00220082360.190
Fly
catabolic processGO:00090563180.186
Human Yeast Mouse Fly
macromolecular complex subunit organizationGO:00439333200.186
proteasomal protein catabolic processGO:0010498200.185
Human Yeast Mouse
cell divisionGO:00513012620.174
regulation of macromolecule metabolic processGO:00602554210.173
multicellular organism reproductionGO:00325048190.169
regulation of mitosisGO:0007088180.168
regulation of rna biosynthetic processGO:20011411650.167
oogenesisGO:00484772290.167
meiotic chromosome segregationGO:00451321390.167
multi organism reproductive processGO:00447038670.164
regulation of nuclear divisionGO:00517831150.163
cytoskeleton organizationGO:00070103390.160
regulation of gene expressionGO:00104683660.160
macromolecule biosynthetic processGO:00090592500.158
mrna processingGO:0006397130.156
organic substance catabolic processGO:19015752940.155
Human Yeast Mouse Fly
organic cyclic compound biosynthetic processGO:19013621950.155
establishment of localizationGO:005123411710.154
sister chromatid segregationGO:0000819460.152
cell motilityGO:00488703130.152
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.151
Human Yeast Mouse
transcription dna templatedGO:00063511680.151
response to chemicalGO:00422213560.146
Fly
rrna metabolic processGO:001607230.144
regulation of cell cycleGO:00517261940.142
regulation of metabolic processGO:00192224780.138
regulation of cell divisionGO:00513021420.137
aromatic compound biosynthetic processGO:00194381920.135
sexual reproductionGO:00199535460.134
protein complex assemblyGO:00064611860.133
negative regulation of gene expressionGO:00106292170.133
regulation of catabolic processGO:0009894570.128
regulation of macromolecule biosynthetic processGO:00105561890.128
regulation of meiosisGO:0040020940.126
metaphase plate congressionGO:005131050.125
cellular macromolecule biosynthetic processGO:00346452470.124
response to biotic stimulusGO:00096071010.122
Worm
microtubule based processGO:00070171820.122
molting cycle collagen and cuticulin based cuticleGO:00189962810.121
cellular protein metabolic processGO:00442672790.116
Human Yeast Mouse
biosynthetic processGO:00090583230.114
negative regulation of macromolecule metabolic processGO:00106052290.114
establishment of spindle localizationGO:0051293510.111
positive regulation of multicellular organism growthGO:00400183520.108
regulation of signalingGO:00230511720.108
Fly
multicellular organismal agingGO:00102598120.107
cellular component biogenesisGO:00440852970.105
cellular component morphogenesisGO:00329893180.103
macromolecular complex assemblyGO:00650031930.102
regulation of signal transductionGO:00099661350.101
Fly
posttranscriptional gene silencingGO:00164411430.100
regulation of nitrogen compound metabolic processGO:00511712220.099
protein catabolic processGO:00301631620.099
Human Yeast Mouse Fly
macromolecule localizationGO:00330367710.098
regulation of rna metabolic processGO:00512521730.097
regulation of multicellular organism growthGO:00400143730.096
regulation of transcription from rna polymerase ii promoterGO:00063571450.095
regulation of growthGO:00400084090.095
regulation of developmental growthGO:00486383890.094
cellular response to stressGO:00335541620.093
Fly
cell migrationGO:00164773060.087
molting cycleGO:00423032810.087
ovipositionGO:00189913640.085
multicellular organism growthGO:00352643850.084
female gamete generationGO:00072922540.083
regulation of transcription dna templatedGO:00063551640.082
regulation of mitotic cell cycleGO:0007346760.081
spindle localizationGO:0051653510.081
protein localizationGO:00081042050.081
regulation of cellular macromolecule biosynthetic processGO:20001121880.081
cellular component movementGO:00069283880.080
regulation of response to stimulusGO:00485832430.080
Fly
protein complex subunit organizationGO:00718222800.080
negative regulation of cellular metabolic processGO:0031324950.078
single organism localizationGO:19025785180.078
developmental growthGO:00485894120.075
dna conformation changeGO:0071103110.074
proteolysisGO:0006508610.074
Human Yeast Mouse
transcription from rna polymerase ii promoterGO:00063661490.073
regulation of biological qualityGO:00650087410.073
positive regulation of nitrogen compound metabolic processGO:00511731340.072
ubiquitin dependent protein catabolic processGO:0006511320.072
Human Yeast Mouse
establishment of localization in cellGO:00516493180.070
protein metabolic processGO:00195384220.070
Human Yeast Mouse Fly
cellular macromolecule catabolic processGO:0044265730.070
Human Yeast Mouse
protein complex biogenesisGO:00702711860.069
single fertilizationGO:0007338610.069
cellular protein modification processGO:00064642070.068
Human Yeast Mouse
regulation of protein catabolic processGO:0042176130.068
posttranscriptional regulation of gene expressionGO:00106081660.068
cellular localizationGO:00516413600.067
organelle assemblyGO:00709252140.067
positive regulation of developmental processGO:00510944080.067
pronuclear migrationGO:0035046510.067
rna interferenceGO:00162461370.066
regulation of multicellular organismal processGO:00512397260.064
cellular biosynthetic processGO:00442493150.063
mitotic sister chromatid segregationGO:0000070380.063
dna templated transcription elongationGO:000635410.062
positive regulation of metabolic processGO:00098931870.062
rna processingGO:0006396340.061
macromolecule modificationGO:00434122180.060
Human Yeast Mouse
neuron differentiationGO:00301822170.057
Fly
aromatic compound catabolic processGO:00194391160.057
regulation of cellular biosynthetic processGO:00313261890.057
positive regulation of developmental growthGO:00486393540.057
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.055
maintenance of locationGO:00512355800.055
lipid localizationGO:00108765730.052
negative regulation of metabolic processGO:00098922400.052
lipid storageGO:00199155650.052
organic substance biosynthetic processGO:19015763230.052
cell proliferationGO:00082831160.051
signal transductionGO:00071653170.051
Fly
transcription elongation from rna polymerase ii promoterGO:000636810.050
programmed cell deathGO:00125015000.048
positive regulation of growthGO:00459273690.048
gene silencingGO:00164581430.048
cellular macromolecular complex assemblyGO:00346221840.048
negative regulation of transcription dna templatedGO:0045892530.047
regulation of cell communicationGO:00106461760.047
Fly
regulation of vulval developmentGO:00400282480.047
nucleic acid templated transcriptionGO:00976591690.047
cytokinesisGO:0000910800.045
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:000037780.045
reproductive behaviorGO:00190983870.044
positive regulation of nucleobase containing compound metabolic processGO:00459351340.044
cell morphogenesisGO:00009021630.044
multicellular organismal reproductive behaviorGO:00330573840.044
regulation of biosynthetic processGO:00098891890.044
regulation of mitotic sister chromatid segregationGO:0033047160.044
multi organism reproductive behaviorGO:00447053870.043
positive regulation of cellular metabolic processGO:00313251780.043
phosphate containing compound metabolic processGO:00067962320.043
gene silencing by rnaGO:00310471430.042
establishment of organelle localizationGO:00516561230.042
response to abiotic stimulusGO:00096281520.040
centrosomal and pronuclear rotationGO:003504760.040
ribosome biogenesisGO:004225440.039
positive regulation of macromolecule metabolic processGO:00106041490.039
nuclear migrationGO:0007097540.038
establishment of nucleus localizationGO:0040023550.038
phosphorus metabolic processGO:00067932320.037
chromosome organization involved in meiosisGO:0070192250.036
negative regulation of nucleic acid templated transcriptionGO:1903507530.035
negative regulation of nitrogen compound metabolic processGO:0051172630.035
posttranscriptional gene silencing by rnaGO:00351941430.034
regulation of catalytic activityGO:0050790780.034
purine nucleoside monophosphate catabolic processGO:0009128280.033
chromatin assembly or disassemblyGO:000633310.033
nucleoside monophosphate metabolic processGO:0009123460.033
positive regulation of rna metabolic processGO:00512541030.033
multi multicellular organism processGO:00447063900.033
negative regulation of macromolecule biosynthetic processGO:0010558650.033
nucleoside phosphate metabolic processGO:00067531080.032
dna templated transcription terminationGO:000635310.032
lipid metabolic processGO:0006629770.032
purine nucleoside metabolic processGO:0042278920.032
mitotic sister chromatid separationGO:0051306130.031
regulation of gene expression epigeneticGO:00400291630.031
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.031
cell morphogenesis involved in neuron differentiationGO:00486671110.031
regulation of cellular catabolic processGO:0031329510.030
regulation of cell differentiationGO:0045595810.030
protein modification processGO:00362112070.030
Human Yeast Mouse
nucleobase containing compound catabolic processGO:00346551140.030
localization of cellGO:00516743130.030
er nucleus signaling pathwayGO:0006984660.029
negative regulation of nematode larval developmentGO:00610642080.029
establishment of spindle orientationGO:0051294340.028
cell type specific apoptotic processGO:009728540.028
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243450.028
fertilizationGO:0009566630.027
regulation of cell proliferationGO:00421271050.027
nucleotide catabolic processGO:0009166770.027
inductive cell migrationGO:00400391450.026
cellular nitrogen compound catabolic processGO:00442701190.026
response to topologically incorrect proteinGO:0035966820.026
regulation of proteolysis involved in cellular protein catabolic processGO:190305050.026
negative regulation of cellular component organizationGO:0051129330.026
cellular response to chemical stimulusGO:00708871290.026
Fly
behaviorGO:00076105270.026
small molecule metabolic processGO:00442811860.026
actin cytoskeleton organizationGO:00300361840.026
cellular macromolecule localizationGO:0070727750.026
multi organism behaviorGO:00517053890.026
striated muscle cell differentiationGO:00511461580.026
negative regulation of nucleobase containing compound metabolic processGO:0045934630.026
regulation of apoptotic signaling pathwayGO:200123310.025
organic cyclic compound catabolic processGO:19013611190.025
metaphase anaphase transition of cell cycleGO:0044784150.025
rna splicingGO:000838080.025
microtubule anchoringGO:003445380.024
response to external biotic stimulusGO:00432071010.024
Worm
regulation of multicellular organismal developmentGO:20000263170.024
purine nucleotide catabolic processGO:0006195750.024
negative regulation of cellular processGO:00485232390.024
neuron developmentGO:00486661990.024
Fly
carbohydrate derivative catabolic processGO:1901136820.023
heterocycle catabolic processGO:00467001190.023
signalingGO:00230524010.023
Fly
negative regulation of rna metabolic processGO:0051253530.023
negative regulation of cellular biosynthetic processGO:0031327650.023
negative regulation of rna biosynthetic processGO:1902679530.023
chromatin organizationGO:0006325320.022
organophosphate metabolic processGO:00196371250.022
single organism transportGO:00447654470.022
regulation of cell deathGO:0010941650.022
rrna processingGO:000636430.022
chromosome localizationGO:0050000100.022
establishment of mitotic spindle localizationGO:0040001410.022
striated muscle cell developmentGO:00550021570.022
establishment of chromosome localizationGO:0051303100.022
cellular response to organic substanceGO:00713101190.021
Fly
cell part morphogenesisGO:00329901520.021
oocyte constructionGO:000730820.021
purine nucleoside catabolic processGO:0006152750.021
dna metabolic processGO:0006259740.021
purine ribonucleoside monophosphate catabolic processGO:0009169280.021
microtubule polymerization or depolymerizationGO:0031109220.021
mitotic spindle organizationGO:0007052810.021
neuron projection morphogenesisGO:00488121140.020
ribonucleoside triphosphate catabolic processGO:0009203720.020
rna localizationGO:000640330.020
maturation of 5 8s rrnaGO:000046010.020
negative regulation of vulval developmentGO:00400272060.020
vulval developmentGO:00400253330.020
anatomical structure formation involved in morphogenesisGO:00486462500.019
glycosyl compound catabolic processGO:1901658790.019
cellular protein complex assemblyGO:00436231780.019
regulation of cellular component biogenesisGO:0044087260.019
mitotic metaphase plate congressionGO:000708050.019
purine nucleotide metabolic processGO:0006163950.019
dna packagingGO:000632370.019
cell projection organizationGO:00300302310.019
macromolecule catabolic processGO:00090572020.018
Human Yeast Mouse Fly
actin filament based processGO:00300291910.018
response to temperature stimulusGO:0009266660.018
positive regulation of cellular protein catabolic processGO:190336430.018
maintenance of protein location in cellGO:0032507120.018
nucleoside triphosphate catabolic processGO:0009143720.018
positive regulation of cellular biosynthetic processGO:00313281090.018
regulation of apoptotic processGO:0042981360.018
homeostatic processGO:0042592510.018
regulation of sister chromatid segregationGO:0033045160.018
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.018
neurological system processGO:0050877530.017
negative regulation of multicellular organismal processGO:00512412360.017
positive regulation of catalytic activityGO:0043085590.017
regulation of chromosome segregationGO:0051983200.017
response to endoplasmic reticulum stressGO:0034976710.016
organelle localizationGO:00516401270.016
mitotic cell cycle checkpointGO:000709350.016
Fly
atp catabolic processGO:0006200270.016
cellular response to abiotic stimulusGO:007121440.016
carbohydrate derivative metabolic processGO:19011351410.016
regulation of cellular protein metabolic processGO:0032268750.016
cleavage involved in rrna processingGO:000046920.016
generation of neuronsGO:00486992350.016
Fly
positive regulation of nucleic acid templated transcriptionGO:19035081020.015
regulation of mrna processingGO:005068470.015
regulation of mitotic spindle organizationGO:006023630.015
head developmentGO:006032210.015
sex determinationGO:0007530600.015
negative regulation of gene expression epigeneticGO:004581420.015
kinetochore organizationGO:005138370.015
chromatin remodelingGO:000633820.015
purine nucleoside monophosphate metabolic processGO:0009126430.015
regulation of chromosome organizationGO:0033044200.015
regulation of protein metabolic processGO:0051246810.015
negative regulation of cell cycleGO:0045786530.015
organic substance transportGO:00717021130.015
purine containing compound catabolic processGO:0072523750.015
muscle cell developmentGO:00550011580.015
spindle checkpointGO:003157740.014
axon developmentGO:00615641630.014
positive regulation of proteasomal protein catabolic processGO:190180010.014
cellular protein localizationGO:0034613750.014
negative regulation of organelle organizationGO:0010639200.014
regulation of microtubule based processGO:0032886210.014
purine ribonucleoside catabolic processGO:0046130750.014
positive regulation of rna biosynthetic processGO:19026801020.014
regulation of localizationGO:00328791940.014
ribonucleotide metabolic processGO:0009259990.014
nucleobase containing small molecule metabolic processGO:00550861150.013
single organism catabolic processGO:00447121290.013
transcription initiation from rna polymerase ii promoterGO:000636720.013
positive regulation of response to stimulusGO:0048584550.013
er associated ubiquitin dependent protein catabolic processGO:003043360.013
mrna catabolic processGO:0006402160.013
membrane organizationGO:00610241350.013
actomyosin structure organizationGO:00310321540.013
regulation of hydrolase activityGO:0051336450.013
purine ribonucleoside metabolic processGO:0046128920.013
mrna splicing via spliceosomeGO:000039880.013
glycosyl compound metabolic processGO:19016571000.013
organ morphogenesisGO:0009887670.013
Mouse
regulation of mrna metabolic processGO:190331170.013
rna splicing via transesterification reactionsGO:000037580.013
negative regulation of developmental processGO:00510932270.013
regulation of anatomical structure morphogenesisGO:0022603510.013
establishment of cell polarityGO:0030010460.013
microtubule cytoskeleton organization involved in mitosisGO:1902850120.013
response to organic substanceGO:00100331310.012
Fly
oocyte axis specificationGO:000730920.012
ribose phosphate metabolic processGO:0019693990.012
nucleoside catabolic processGO:0009164780.012
regulation of nematode larval developmentGO:00610622600.012
developmental maturationGO:0021700260.012
Fly
nucleoside metabolic processGO:0009116990.012
ribonucleoside metabolic processGO:0009119980.012
nucleoside triphosphate metabolic processGO:0009141870.012
single organism cellular localizationGO:1902580720.012
mitotic g2 m transition checkpointGO:004481810.012
Fly
collagen and cuticulin based cuticle developmentGO:0040002990.012
regulation of synapse assemblyGO:005196320.012
negative regulation of cell cycle processGO:0010948120.012
Fly
regulation of post embryonic developmentGO:00485802600.012
regulation of nucleocytoplasmic transportGO:004682230.012
meiosis iiGO:0007135160.012
chromatin assemblyGO:003149710.012
purine ribonucleoside monophosphate metabolic processGO:0009167430.012
nucleotide metabolic processGO:00091171080.012
myosin filament organizationGO:00310331380.012
ribonucleoprotein complex assemblyGO:002261840.011
protein modification by small protein conjugation or removalGO:0070647400.011
Human Yeast Mouse
intracellular receptor signaling pathwayGO:003052220.011
regulation of intracellular signal transductionGO:1902531770.011
Fly
chromosome condensationGO:003026160.011
regulation of programmed cell deathGO:0043067500.011
protein modification by small protein conjugationGO:0032446310.011
Human Yeast Mouse
intracellular signal transductionGO:0035556960.011
Fly
positive regulation of protein transportGO:005122240.011
negative regulation of proteolysis involved in cellular protein catabolic processGO:190305140.011
ribonucleoside monophosphate catabolic processGO:0009158280.010
spermatogenesisGO:0007283410.010
neuromuscular junction developmentGO:000752820.010
regulation of microtubule cytoskeleton organizationGO:0070507210.010
myosin filament assemblyGO:00310341380.010
axonogenesisGO:00074091020.010
single organism biosynthetic processGO:0044711910.010
cell cycle phase transitionGO:0044770190.010
Yeast Fly
defense response to bacteriumGO:0042742860.010
establishment of mitotic spindle orientationGO:0000132280.010
myofibril assemblyGO:00302391540.010
regulation of cytoskeleton organizationGO:0051493410.010
cellular component assembly involved in morphogenesisGO:00109271830.010
germ line stem cell divisionGO:004207890.010
immune responseGO:00069551920.010

cul-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
nervous system diseaseDOID:86300.018
disease of cellular proliferationDOID:1456600.012