Caenorhabditis elegans

207 known processes

sca-1 (CELE_K11D9.2)

Protein SCA-1

sca-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.835
embryo development ending in birth or egg hatchingGO:000979229920.811
post embryonic developmentGO:000979121520.665
cellular localizationGO:00516413600.567
Mouse
establishment of localizationGO:005123411710.557
sex differentiationGO:00075489090.369
locomotionGO:004001116340.326
establishment of localization in cellGO:00516493180.286
Mouse
transportGO:000681010930.283
regulation of multicellular organismal processGO:00512397260.279
Human Zebrafish Mouse
sexual reproductionGO:00199535460.252
organic cyclic compound biosynthetic processGO:19013621950.247
single organism transportGO:00447654470.243
regulation of developmental processGO:00507936840.233
negative regulation of biological processGO:00485195670.230
Zebrafish Mouse
receptor mediated endocytosisGO:00068987150.228
regulation of cellular macromolecule biosynthetic processGO:20001121880.222
developmental process involved in reproductionGO:000300611650.204
single organism reproductive processGO:004470211960.204
reproductive structure developmentGO:00486088500.197
aromatic compound biosynthetic processGO:00194381920.197
cellular nitrogen compound biosynthetic processGO:00442711920.196
heterocycle biosynthetic processGO:00181301870.195
organelle organizationGO:00069967830.191
gonad developmentGO:00084068400.186
deathGO:00162655470.185
growthGO:00400075620.178
response to chemicalGO:00422213560.177
biosynthetic processGO:00090583230.176
Fly
multicellular organismal agingGO:00102598120.170
determination of adult lifespanGO:00083408120.168
transcription dna templatedGO:00063511680.163
single organism signalingGO:00447004010.161
regulation of nematode larval developmentGO:00610622600.159
microtubule based processGO:00070171820.154
regulation of metabolic processGO:00192224780.153
Fly
development of primary sexual characteristicsGO:00451378400.150
vesicle mediated transportGO:00161928520.149
agingGO:00075688120.149
multicellular organism reproductionGO:00325048190.146
regulation of signalingGO:00230511720.143
Mouse
endocytosisGO:00068978190.133
molting cycleGO:00423032810.133
regulation of macromolecule metabolic processGO:00602554210.127
regulation of transcription from rna polymerase ii promoterGO:00063571450.127
regulation of post embryonic developmentGO:00485802600.123
protein localizationGO:00081042050.122
organic substance biosynthetic processGO:19015763230.121
Fly
reproductive system developmentGO:00614588500.121
regulation of rna biosynthetic processGO:20011411650.120
post embryonic organ developmentGO:00485693360.120
nucleobase containing compound biosynthetic processGO:00346541840.119
cellular biosynthetic processGO:00442493150.114
tissue developmentGO:00098881120.113
Zebrafish
vulval developmentGO:00400253330.109
cell deathGO:00082195470.109
cytoskeleton organizationGO:00070103390.107
regulation of vulval developmentGO:00400282480.105
regulation of transcription dna templatedGO:00063551640.105
cell cycleGO:00070495260.104
regulation of multicellular organismal developmentGO:20000263170.103
body morphogenesisGO:00101716200.101
nucleic acid templated transcriptionGO:00976591690.101
programmed cell deathGO:00125015000.100
regulation of growthGO:00400084090.097
macromolecule localizationGO:00330367710.096
Fly
cellular component morphogenesisGO:00329893180.095
regulation of localizationGO:00328791940.095
Mouse Fly
hermaphrodite genitalia developmentGO:00400357340.094
regulation of nucleic acid templated transcriptionGO:19035061650.093
organ developmentGO:004851311020.092
Zebrafish
negative regulation of cellular processGO:00485232390.090
cellular response to organic substanceGO:00713101190.090
axon guidanceGO:0007411820.089
signal transductionGO:00071653170.088
cellular response to chemical stimulusGO:00708871290.088
response to external stimulusGO:00096052890.088
apoptotic processGO:00069154780.086
multicellular organismal reproductive processGO:00486098150.085
macromolecule biosynthetic processGO:00090592500.084
axon developmentGO:00615641630.083
multi organism behaviorGO:00517053890.082
multi organism reproductive processGO:00447038670.082
negative regulation of nematode larval developmentGO:00610642080.082
protein metabolic processGO:00195384220.081
positive regulation of multicellular organismal processGO:00512404170.081
regulation of gene expressionGO:00104683660.081
negative regulation of vulval developmentGO:00400272060.081
behaviorGO:00076105270.080
Fly
cellular protein metabolic processGO:00442672790.079
positive regulation of cellular processGO:00485223320.077
Fly
response to abiotic stimulusGO:00096281520.077
Zebrafish
single organism localizationGO:19025785180.077
rna biosynthetic processGO:00327741690.076
regulation of biological qualityGO:00650087410.076
positive regulation of growthGO:00459273690.076
nucleobase containing compound metabolic processGO:00061394060.075
genitalia developmentGO:00488067410.074
nucleic acid metabolic processGO:00903042990.073
spindle organizationGO:0007051920.072
gene expressionGO:00104674120.072
regulation of macromolecule biosynthetic processGO:00105561890.071
positive regulation of developmental growthGO:00486393540.071
positive regulation of developmental processGO:00510944080.070
dauer larval developmentGO:0040024920.070
regulation of primary metabolic processGO:00800902920.068
Fly
regulation of response to stimulusGO:00485832430.067
Mouse
anatomical structure formation involved in morphogenesisGO:00486462500.067
rna metabolic processGO:00160702280.066
lipid storageGO:00199155650.065
Fly
mitotic spindle organizationGO:0007052810.065
cellular component biogenesisGO:00440852970.065
signalingGO:00230524010.065
taxisGO:00423301280.064
purine nucleoside triphosphate metabolic processGO:0009144870.062
localization of cellGO:00516743130.061
embryonic morphogenesisGO:00485981520.061
Zebrafish
response to temperature stimulusGO:0009266660.061
lipid localizationGO:00108765730.060
Fly
ovipositionGO:00189913640.060
regulation of rna metabolic processGO:00512521730.060
cellular catabolic processGO:00442481990.060
cellular macromolecule biosynthetic processGO:00346452470.059
germ cell developmentGO:00072813510.059
secretion by cellGO:00329401380.057
Mouse
cell fate commitmentGO:00451651390.057
negative regulation of metabolic processGO:00098922400.056
negative regulation of nucleic acid templated transcriptionGO:1903507530.056
cell cycle processGO:00224024820.056
cellular component movementGO:00069283880.055
cell surface receptor signaling pathwayGO:00071661490.055
regulation of cellular component organizationGO:00511282480.054
organic substance catabolic processGO:19015752940.054
negative regulation of multicellular organismal processGO:00512412360.054
Zebrafish Mouse
mitotic cell cycle processGO:19030471940.054
transcription from rna polymerase ii promoterGO:00063661490.054
developmental growthGO:00485894120.054
negative regulation of gene expressionGO:00106292170.053
transmembrane transportGO:00550851100.053
gamete generationGO:00072764610.052
maintenance of locationGO:00512355800.052
Fly
adult behaviorGO:003053430.052
Fly
head developmentGO:006032210.052
ion transmembrane transportGO:0034220910.051
regulation of multicellular organism growthGO:00400143730.051
oocyte constructionGO:000730820.050
muscle tissue developmentGO:006053710.049
oogenesisGO:00484772290.049
macromolecular complex subunit organizationGO:00439333200.048
chemotaxisGO:00069351200.048
nucleoside triphosphate metabolic processGO:0009141870.048
positive regulation of macromolecule metabolic processGO:00106041490.047
protein complex subunit organizationGO:00718222800.047
positive regulation of cellular biosynthetic processGO:00313281090.047
system processGO:00030081360.046
Human Zebrafish Mouse Fly
purine nucleotide metabolic processGO:0006163950.046
phosphate containing compound metabolic processGO:00067962320.046
nucleotide metabolic processGO:00091171080.046
multi multicellular organism processGO:00447063900.046
negative regulation of macromolecule metabolic processGO:00106052290.046
sensory organ morphogenesisGO:009059620.045
carbohydrate derivative metabolic processGO:19011351410.045
regulation of developmental growthGO:00486383890.045
female gamete generationGO:00072922540.045
mitotic nuclear divisionGO:0007067890.044
epithelium developmentGO:0060429680.044
Zebrafish
regulation of cell proliferationGO:00421271050.044
meiotic nuclear divisionGO:00071263000.044
positive regulation of multicellular organism growthGO:00400183520.043
cellular macromolecule localizationGO:0070727750.043
negative regulation of post embryonic developmentGO:00485812080.043
reproductive behaviorGO:00190983870.043
cellular component assemblyGO:00226072930.042
negative regulation of developmental processGO:00510932270.042
regulation of nucleocytoplasmic transportGO:004682230.042
regulation of biosynthetic processGO:00098891890.041
regulation of nucleobase containing compound metabolic processGO:00192192220.041
Fly
multicellular organism growthGO:00352643850.041
single organism organelle organizationGO:19025895010.040
secretionGO:00469031470.039
Mouse
regulation of cellular biosynthetic processGO:00313261890.039
ribonucleoside monophosphate metabolic processGO:0009161450.039
cell divisionGO:00513012620.039
multi organism reproductive behaviorGO:00447053870.038
regulation of anatomical structure morphogenesisGO:0022603510.038
protein complex assemblyGO:00064611860.038
regulation of anatomical structure sizeGO:0090066460.037
meiotic cell cycleGO:00513213350.036
response to organic substanceGO:00100331310.036
pattern specification processGO:0007389590.036
Zebrafish
positive regulation of nitrogen compound metabolic processGO:00511731340.036
Fly
oocyte axis specificationGO:000730920.035
neurogenesisGO:00220082360.034
macromolecule modificationGO:00434122180.034
organic substance transportGO:00717021130.034
regionalizationGO:0003002310.034
positive regulation of cell morphogenesis involved in differentiationGO:001077040.034
regulation of signal transductionGO:00099661350.034
meiotic cell cycle processGO:19030461700.034
organ morphogenesisGO:0009887670.033
Zebrafish
negative regulation of biosynthetic processGO:0009890650.033
macromolecular complex assemblyGO:00650031930.033
maintenance of location in cellGO:0051651120.033
posttranscriptional regulation of gene expressionGO:00106081660.033
regulation of organelle organizationGO:00330431640.033
cell developmentGO:00484686960.033
catabolic processGO:00090563180.033
ribonucleoside catabolic processGO:0042454770.032
regulation of cytoplasmic transportGO:190364930.032
lipid biosynthetic processGO:0008610280.031
Fly
nervous system developmentGO:00073992530.031
membrane organizationGO:00610241350.031
macromolecule catabolic processGO:00090572020.030
skeletal muscle organ developmentGO:006053830.030
nucleoside monophosphate metabolic processGO:0009123460.030
regulation of meiotic cell cycleGO:00514451360.030
oxoacid metabolic processGO:0043436470.029
Fly
single organism biosynthetic processGO:0044711910.029
Fly
multicellular organismal reproductive behaviorGO:00330573840.029
negative regulation of cellular metabolic processGO:0031324950.029
cell morphogenesis involved in differentiationGO:00009041120.029
cellular nitrogen compound catabolic processGO:00442701190.029
regulation of cell communicationGO:00106461760.029
Mouse
regulation of cellular metabolic processGO:00313233050.029
Fly
molting cycle collagen and cuticulin based cuticleGO:00189962810.029
cellular protein localizationGO:0034613750.028
cell cell signalingGO:00072671180.028
Mouse Fly
response to heatGO:0009408500.028
cellular protein modification processGO:00064642070.028
protein complex biogenesisGO:00702711860.028
positive regulation of transportGO:0051050320.028
Fly
inorganic ion transmembrane transportGO:0098660540.027
cell growthGO:0016049440.027
cell morphogenesisGO:00009021630.027
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.027
organelle fissionGO:00482853630.027
cell motilityGO:00488703130.026
purine nucleoside monophosphate metabolic processGO:0009126430.026
cellular process involved in reproduction in multicellular organismGO:00224123510.026
positive regulation of intracellular transportGO:003238820.025
organelle assemblyGO:00709252140.025
negative regulation of nucleobase containing compound metabolic processGO:0045934630.025
negative regulation of nitrogen compound metabolic processGO:0051172630.025
neuron differentiationGO:00301822170.025
nucleoside metabolic processGO:0009116990.024
response to woundingGO:000961140.024
epithelial tube morphogenesisGO:006056210.024
Zebrafish
small molecule metabolic processGO:00442811860.024
digestive system developmentGO:00551231220.024
regulation of cell cycleGO:00517261940.024
small gtpase mediated signal transductionGO:0007264320.023
calcium mediated signalingGO:001972230.023
Human
regulation of catabolic processGO:0009894570.023
Fly
fertilizationGO:0009566630.023
cell migrationGO:00164773060.023
neuron recognitionGO:0008038830.023
generation of neuronsGO:00486992350.023
divalent metal ion transportGO:0070838170.022
chromosome organizationGO:00512761040.022
cellular macromolecular complex assemblyGO:00346221840.022
intracellular transportGO:0046907770.022
positive regulation of macromolecule biosynthetic processGO:00105571090.021
phagocytosisGO:00069091150.021
positive regulation of cellular metabolic processGO:00313251780.021
Fly
regulation of epithelial cell proliferationGO:005067810.021
ribose phosphate metabolic processGO:0019693990.021
dna metabolic processGO:0006259740.021
regulation of sequence specific dna binding transcription factor activityGO:005109030.020
cation transmembrane transportGO:0098655590.020
positive regulation of signalingGO:0023056660.020
nitrogen compound transportGO:0071705490.020
intracellular signal transductionGO:0035556960.020
Human
epithelial cell proliferationGO:005067310.020
gene silencingGO:00164581430.020
protein modification processGO:00362112070.020
organic acid metabolic processGO:0006082470.019
Fly
negative regulation of cellular biosynthetic processGO:0031327650.019
regulation of protein localizationGO:0032880500.019
metal ion transportGO:0030001490.019
rna localizationGO:000640330.019
regulation of locomotionGO:00400121610.019
negative regulation of neurogenesisGO:005076840.019
regulation of cell morphogenesisGO:0022604400.019
cell type specific apoptotic processGO:009728540.018
regulation of cell deathGO:0010941650.018
regulation of meiosisGO:0040020940.018
regulation of nitrogen compound metabolic processGO:00511712220.018
Fly
single organism cellular localizationGO:1902580720.018
regulation of protein targetingGO:190353330.018
intracellular receptor signaling pathwayGO:003052220.018
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.018
muscle structure developmentGO:00610611910.018
ribosome biogenesisGO:004225440.018
cellular amino acid metabolic processGO:0006520150.018
negative regulation of cell communicationGO:0010648610.018
negative regulation of signalingGO:0023057610.018
positive regulation of protein transportGO:005122240.017
regulation of cellular ketone metabolic processGO:001056530.017
actin filament based processGO:00300291910.017
maintenance of protein location in cellGO:0032507120.017
cell proliferationGO:00082831160.017
cell projection morphogenesisGO:00488581480.017
small molecule biosynthetic processGO:0044283380.017
positive regulation of cell communicationGO:0010647690.017
ribonucleoside triphosphate metabolic processGO:0009199870.017
regulation of cellular component sizeGO:0032535400.017
regulation of ion transportGO:0043269390.016
Fly
positive regulation of catabolic processGO:0009896380.016
Fly
regulation of gene expression epigeneticGO:00400291630.016
neuron projection morphogenesisGO:00488121140.016
cellular response to endogenous stimulusGO:0071495320.016
homeostatic processGO:0042592510.016
regulation of cell cycle processGO:00105641450.016
regulation of cytoskeleton organizationGO:0051493410.016
skin developmentGO:0043588240.016
cytoplasmic transportGO:0016482230.016
regulation of calcium ion transportGO:005192430.016
Fly
memoryGO:000761330.016
cuticle developmentGO:00423351000.016
regulation of cellular localizationGO:0060341420.016
Mouse
posttranscriptional gene silencing by rnaGO:00351941430.016
synaptic transmissionGO:00072681060.016
Mouse Fly
ribonucleotide metabolic processGO:0009259990.016
tissue morphogenesisGO:0048729650.016
Zebrafish
neuron projection guidanceGO:0097485820.016
positive regulation of response to stimulusGO:0048584550.015
negative regulation of response to stimulusGO:0048585730.015
axonogenesisGO:00074091020.015
cellular response to stressGO:00335541620.015
regulation of apoptotic signaling pathwayGO:200123310.015
oxidation reduction processGO:0055114590.015
Fly
striated muscle cell differentiationGO:00511461580.015
regulation of cell divisionGO:00513021420.015
regulation of endocytosisGO:0030100250.015
positive regulation of cell cycleGO:0045787550.015
neuron projection developmentGO:00311751870.015
neuron developmentGO:00486661990.015
amine catabolic processGO:000931010.015
microtubule cytoskeleton organization involved in mitosisGO:1902850120.015
meiotic chromosome segregationGO:00451321390.015
cell morphogenesis involved in neuron differentiationGO:00486671110.015
single organism intracellular transportGO:1902582700.015
positive regulation of metabolic processGO:00098931870.014
Fly
hormone transportGO:000991420.014
positive regulation of transcription dna templatedGO:00458931020.014
purine ribonucleotide metabolic processGO:0009150950.014
regulation of small gtpase mediated signal transductionGO:0051056410.014
protein catabolic processGO:00301631620.014
embryonic body morphogenesisGO:0010172490.014
regulation of protein stabilityGO:003164730.014
maintenance of protein locationGO:0045185150.014
carboxylic acid catabolic processGO:004639530.014
Fly
positive regulation of gene expressionGO:00106281120.014
organonitrogen compound biosynthetic processGO:1901566440.014
aromatic compound catabolic processGO:00194391160.014
regulation of lipid biosynthetic processGO:004689010.013
establishment of organelle localizationGO:00516561230.013
rna interferenceGO:00162461370.013
actin cytoskeleton organizationGO:00300361840.013
positive regulation of small gtpase mediated signal transductionGO:005105770.013
cellular ketone metabolic processGO:0042180140.013
response to oxygen containing compoundGO:1901700440.013
organophosphate metabolic processGO:00196371250.013
adult locomotory behaviorGO:000834410.013
Fly
tube developmentGO:00352951260.013
Zebrafish
actin cytoskeleton reorganizationGO:003153240.013
regulation of behaviorGO:0050795970.013
positive regulation of nucleobase containing compound metabolic processGO:00459351340.013
Fly
carbohydrate derivative biosynthetic processGO:1901137460.013
purine ribonucleoside monophosphate metabolic processGO:0009167430.013
organonitrogen compound metabolic processGO:19015641510.013
positive regulation of cell migrationGO:003033530.013
protein modification by small protein conjugation or removalGO:0070647400.013
neuromuscular junction developmentGO:000752820.013
regulation of apoptotic processGO:0042981360.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.013
protein oligomerizationGO:005125940.013
negative regulation of signal transductionGO:0009968600.012
collagen and cuticulin based cuticle developmentGO:0040002990.012
digestive tract morphogenesisGO:0048546760.012
signal releaseGO:0023061280.012
Mouse
regulation of lipid metabolic processGO:001921640.012
spermatogenesisGO:0007283410.012
translational initiationGO:000641320.012
single organism membrane organizationGO:0044802350.012
neurological system processGO:0050877530.012
gene silencing by rnaGO:00310471430.012
neuromuscular processGO:005090510.012
g protein coupled receptor signaling pathwayGO:0007186460.012
inorganic cation transmembrane transportGO:0098662460.012
regulation of cell differentiationGO:0045595810.012
positive regulation of intracellular protein transportGO:009031620.012
male gamete generationGO:0048232410.012
cellular response to unfolded proteinGO:0034620710.012
cgmp metabolic processGO:004606820.012
oocyte developmentGO:0048599440.012
organelle localizationGO:00516401270.012
regulation of programmed cell deathGO:0043067500.012
cellular macromolecule catabolic processGO:0044265730.011
posttranscriptional gene silencingGO:00164411430.011
digestive tract developmentGO:00485651220.011
neuron apoptotic processGO:005140240.011
muscle cell developmentGO:00550011580.011
purine ribonucleoside metabolic processGO:0046128920.011
positive regulation of biosynthetic processGO:00098911090.011
negative regulation of rna metabolic processGO:0051253530.011
atp metabolic processGO:0046034420.011
purine ribonucleotide catabolic processGO:0009154750.011
negative regulation of transcription dna templatedGO:0045892530.011
ribonucleoside metabolic processGO:0009119980.011
nucleoside catabolic processGO:0009164780.011
cytosolic calcium ion homeostasisGO:005148020.011
regulation of transportGO:0051049910.011
Mouse Fly
regulation of development heterochronicGO:0040034180.011
response to inorganic substanceGO:0010035500.011
response to acid chemicalGO:000110140.010
cation transportGO:0006812780.010
muscle cell differentiationGO:00426921710.010
ion transportGO:00068111130.010
single organism behaviorGO:0044708830.010
Fly
amine metabolic processGO:0009308150.010
cellular component assembly involved in morphogenesisGO:00109271830.010
carboxylic acid metabolic processGO:0019752340.010
Fly
negative regulation of cytosolic calcium ion concentrationGO:005148110.010
positive regulation of nucleic acid templated transcriptionGO:19035081020.010
positive regulation of rna metabolic processGO:00512541030.010
negative regulation of rna biosynthetic processGO:1902679530.010
establishment of mitotic spindle localizationGO:0040001410.010

sca-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
Human
disease of metabolismDOID:001466700.027
nervous system diseaseDOID:86300.021
inherited metabolic disorderDOID:65500.014
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013