IMP: Integrative Multi-species Prediction

Caenorhabditis elegans

0 known processes

unc-17 (CELE_ZC416.8a)

Protein UNC-17

Entrez: 13192684
UniProtKB: P34711

Process Predictions
Disease Predictions

unc-17 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
synaptic transmission	GO:0007268	106	0.353
establishment of localization	GO:0051234	1171	0.290
embryo development	GO:0009790	3052	0.253
transport	GO:0006810	1093	0.251
signaling	GO:0023052	401	0.250
signal transduction	GO:0007165	317	0.192
embryo development ending in birth or egg hatching	GO:0009792	2992	0.185
single organism signaling	GO:0044700	401	0.174
single organism localization	GO:1902578	518	0.169
regulation of locomotion	GO:0040012	161	0.162
positive regulation of cellular process	GO:0048522	332	0.157
regulation of response to stimulus	GO:0048583	243	0.149
locomotion	GO:0040011	1634	0.144
vesicle mediated transport	GO:0016192	852	0.143
regulation of cell communication	GO:0010646	176	0.128
post embryonic development	GO:0009791	2152	0.120
behavior	GO:0007610	527	0.117
endocytosis	GO:0006897	819	0.115
multi organism reproductive process	GO:0044703	867	0.115
cellular localization	GO:0051641	360	0.114
secretion	GO:0046903	147	0.111
organelle organization	GO:0006996	783	0.105
regulation of multicellular organismal development	GO:2000026	317	0.101
g protein coupled receptor signaling pathway	GO:0007186	46	0.100
secretion by cell	GO:0032940	138	0.095
regulation of biological quality	GO:0065008	741	0.094
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	34	0.093
cellular component assembly	GO:0022607	293	0.090
synaptic vesicle recycling	GO:0036465	3	0.084
regulation of feeding behavior	GO:0060259	38	0.080
single organism transport	GO:0044765	447	0.079
macromolecule localization	GO:0033036	771	0.078
single organism reproductive process	GO:0044702	1196	0.077
cell development	GO:0048468	696	0.074
cell cell signaling	GO:0007267	118	0.073
regulation of signaling	GO:0023051	172	0.072
skeletal muscle organ development	GO:0060538	3	0.069
organic substance catabolic process	GO:1901575	294	0.068
protein complex subunit organization	GO:0071822	280	0.067
maintenance of location	GO:0051235	580	0.066
cell surface receptor signaling pathway	GO:0007166	149	0.066
regulation of developmental process	GO:0050793	684	0.065
ion transport	GO:0006811	113	0.063
developmental process involved in reproduction	GO:0003006	1165	0.063
positive regulation of cell communication	GO:0010647	69	0.062
establishment of localization in cell	GO:0051649	318	0.059
regulation of synapse assembly	GO:0051963	2	0.059
response to chemical	GO:0042221	356	0.058
signal release	GO:0023061	28	0.058
regulation of reproductive process	GO:2000241	66	0.057
head development	GO:0060322	1	0.056
cytoskeleton organization	GO:0007010	339	0.056
neuron development	GO:0048666	199	0.055
lipid storage	GO:0019915	565	0.055
determination of adult lifespan	GO:0008340	812	0.054
sexual reproduction	GO:0019953	546	0.054
organ development	GO:0048513	1102	0.054
regulation of multicellular organismal process	GO:0051239	726	0.049
cellular component biogenesis	GO:0044085	297	0.048
synaptic vesicle localization	GO:0097479	22	0.047
regulation of cellular component organization	GO:0051128	248	0.047
lipid localization	GO:0010876	573	0.047
regulation of cellular metabolic process	GO:0031323	305	0.046
regulation of behavior	GO:0050795	97	0.046
reproductive system development	GO:0061458	850	0.046
cellular component morphogenesis	GO:0032989	318	0.046
purine ribonucleoside triphosphate metabolic process	GO:0009205	87	0.045
single organism organelle organization	GO:1902589	501	0.044
actin filament based process	GO:0030029	191	0.043
development of primary sexual characteristics	GO:0045137	840	0.043
cell morphogenesis involved in differentiation	GO:0000904	112	0.043
establishment of organelle localization	GO:0051656	123	0.043
multicellular organismal reproductive process	GO:0048609	815	0.042
chemotaxis	GO:0006935	120	0.042
regulation of localization	GO:0032879	194	0.042
multicellular organismal aging	GO:0010259	812	0.042
nervous system development	GO:0007399	253	0.042
generation of neurons	GO:0048699	235	0.042
positive regulation of signaling	GO:0023056	66	0.042
regulation of phosphate metabolic process	GO:0019220	81	0.041
transmembrane transport	GO:0055085	110	0.040
neurogenesis	GO:0022008	236	0.039
multicellular organism reproduction	GO:0032504	819	0.039
locomotory behavior	GO:0007626	40	0.038
macromolecule modification	GO:0043412	218	0.038
regulation of multi organism process	GO:0043900	69	0.038
acetylcholine catabolic process	GO:0006581	4	0.038
establishment of synaptic vesicle localization	GO:0097480	21	0.037
eating behavior	GO:0042755	59	0.037
ion transmembrane transport	GO:0034220	91	0.037
phosphorus metabolic process	GO:0006793	232	0.037
acetate ester metabolic process	GO:1900619	4	0.037
hermaphrodite genitalia development	GO:0040035	734	0.036
synaptic vesicle transport	GO:0048489	21	0.036
single organism membrane organization	GO:0044802	35	0.036
regulation of neurotransmitter levels	GO:0001505	36	0.035
organelle localization	GO:0051640	127	0.035
cell projection organization	GO:0030030	231	0.034
actin cytoskeleton organization	GO:0030036	184	0.034
catabolic process	GO:0009056	318	0.034
aging	GO:0007568	812	0.034
macromolecular complex assembly	GO:0065003	193	0.033
vesicle localization	GO:0051648	24	0.033
cellular protein metabolic process	GO:0044267	279	0.033
cellular component movement	GO:0006928	388	0.032
axonogenesis	GO:0007409	102	0.032
membrane organization	GO:0061024	135	0.032
single organism cellular localization	GO:1902580	72	0.032
neuron projection guidance	GO:0097485	82	0.032
negative regulation of biological process	GO:0048519	567	0.032
multi multicellular organism process	GO:0044706	390	0.032
protein complex assembly	GO:0006461	186	0.031
memory	GO:0007613	3	0.031
pharyngeal pumping	GO:0043050	58	0.031
body morphogenesis	GO:0010171	620	0.031
regulation of cell development	GO:0060284	49	0.031
cell part morphogenesis	GO:0032990	152	0.030
phosphate containing compound metabolic process	GO:0006796	232	0.030
regulation of organelle organization	GO:0033043	164	0.030
nucleoside phosphate metabolic process	GO:0006753	108	0.030
regulation of signal transduction	GO:0009966	135	0.029
inorganic ion transmembrane transport	GO:0098660	54	0.029
response to organic substance	GO:0010033	131	0.029
protein complex biogenesis	GO:0070271	186	0.029
gonad development	GO:0008406	840	0.028
multicellular organismal reproductive behavior	GO:0033057	384	0.028
cell projection morphogenesis	GO:0048858	148	0.028
regulation of developmental growth	GO:0048638	389	0.028
protein metabolic process	GO:0019538	422	0.027
intracellular signal transduction	GO:0035556	96	0.027
regulation of molecular function	GO:0065009	89	0.027
reproductive structure development	GO:0048608	850	0.027
regulation of neuromuscular synaptic transmission	GO:1900073	1	0.027
anatomical structure formation involved in morphogenesis	GO:0048646	250	0.027
sex differentiation	GO:0007548	909	0.027
muscle system process	GO:0003012	43	0.027
positive regulation of phosphorus metabolic process	GO:0010562	56	0.026
neurotransmitter secretion	GO:0007269	26	0.026
organonitrogen compound metabolic process	GO:1901564	151	0.026
positive regulation of transferase activity	GO:0051347	21	0.026
localization of cell	GO:0051674	313	0.026
nucleobase containing small molecule metabolic process	GO:0055086	115	0.026
regulation of cytoskeleton organization	GO:0051493	41	0.026
cellular protein complex assembly	GO:0043623	178	0.025
cellular macromolecule localization	GO:0070727	75	0.025
establishment of vesicle localization	GO:0051650	23	0.025
regulation of synaptic plasticity	GO:0048167	1	0.024
protein modification process	GO:0036211	207	0.024
reproductive behavior	GO:0019098	387	0.024
cell type specific apoptotic process	GO:0097285	4	0.024
death	GO:0016265	547	0.024
regulation of nitrogen compound metabolic process	GO:0051171	222	0.024
positive regulation of phosphate metabolic process	GO:0045937	56	0.024
regulation of metabolic process	GO:0019222	478	0.024
synaptic transmission cholinergic	GO:0007271	21	0.023
cellular protein localization	GO:0034613	75	0.023
cell morphogenesis	GO:0000902	163	0.023
synaptic vesicle exocytosis	GO:0016079	5	0.023
organelle assembly	GO:0070925	214	0.023
ribonucleotide metabolic process	GO:0009259	99	0.023
regulation of cellular amino acid metabolic process	GO:0006521	0	0.023
genitalia development	GO:0048806	741	0.022
regulation of neurotransmitter secretion	GO:0046928	16	0.022
nucleotide metabolic process	GO:0009117	108	0.022
macromolecular complex subunit organization	GO:0043933	320	0.022
taxis	GO:0042330	128	0.022
cellular protein modification process	GO:0006464	207	0.022
regulation of transport	GO:0051049	91	0.022
cell morphogenesis involved in neuron differentiation	GO:0048667	111	0.022
regulation of growth	GO:0040008	409	0.022
cellular amine metabolic process	GO:0044106	15	0.022
cell death	GO:0008219	547	0.022
regulation of cell cycle process	GO:0010564	145	0.021
positive regulation of protein kinase activity	GO:0045860	18	0.021
multi organism reproductive behavior	GO:0044705	387	0.021
cellular macromolecular complex assembly	GO:0034622	184	0.021
multicellular organism growth	GO:0035264	385	0.021
regulation of cellular amine metabolic process	GO:0033238	0	0.021
carbohydrate derivative metabolic process	GO:1901135	141	0.020
cellular process involved in reproduction in multicellular organism	GO:0022412	351	0.020
regulation of catalytic activity	GO:0050790	78	0.020
neuron projection development	GO:0031175	187	0.020
cell cycle	GO:0007049	526	0.020
regulation of pharyngeal pumping	GO:0043051	36	0.020
system process	GO:0003008	136	0.020
cellular response to chemical stimulus	GO:0070887	129	0.020
regulation of synaptic transmission	GO:0050804	34	0.020
positive regulation of multicellular organismal process	GO:0051240	417	0.019
positive regulation of cell cycle	GO:0045787	55	0.019
cell cycle process	GO:0022402	482	0.019
protein oligomerization	GO:0051259	4	0.019
response to external stimulus	GO:0009605	289	0.019
receptor mediated endocytosis	GO:0006898	715	0.019
neurotransmitter transport	GO:0006836	32	0.019
multi organism behavior	GO:0051705	389	0.019
purine ribonucleotide metabolic process	GO:0009150	95	0.019
protein phosphorylation	GO:0006468	85	0.019
positive regulation of transport	GO:0051050	32	0.018
regulation of acetylcholine secretion neurotransmission	GO:0014056	9	0.018
neurological system process	GO:0050877	53	0.018
regulation of system process	GO:0044057	27	0.018
regulation of cell morphogenesis	GO:0022604	40	0.018
cell maturation	GO:0048469	26	0.018
neuron neuron synaptic transmission	GO:0007270	22	0.018
cyclic nucleotide metabolic process	GO:0009187	2	0.018
organophosphate metabolic process	GO:0019637	125	0.018
synaptic vesicle endocytosis	GO:0048488	3	0.018
regulation of multicellular organism growth	GO:0040014	373	0.018
regulation of striated muscle contraction	GO:0006942	4	0.018
organic substance transport	GO:0071702	113	0.018
muscle cell differentiation	GO:0042692	171	0.018
positive regulation of protein transport	GO:0051222	4	0.018
feeding behavior	GO:0007631	70	0.018
nucleobase containing compound metabolic process	GO:0006139	406	0.017
positive regulation of growth	GO:0045927	369	0.017
anion transport	GO:0006820	30	0.017
organic substance biosynthetic process	GO:1901576	323	0.017
cation transport	GO:0006812	78	0.017
protein localization	GO:0008104	205	0.017
regulation of biosynthetic process	GO:0009889	189	0.017
acetylcholine metabolic process	GO:0008291	4	0.017
growth	GO:0040007	562	0.017
nitrogen compound transport	GO:0071705	49	0.017
regulation of macromolecule metabolic process	GO:0060255	421	0.017
muscle cell development	GO:0055001	158	0.017
oocyte development	GO:0048599	44	0.016
negative regulation of developmental process	GO:0051093	227	0.016
positive regulation of molecular function	GO:0044093	61	0.016
regulation of cell differentiation	GO:0045595	81	0.016
neuron projection morphogenesis	GO:0048812	114	0.016
developmental maturation	GO:0021700	26	0.016
small molecule metabolic process	GO:0044281	186	0.016
axon development	GO:0061564	163	0.016
inductive cell migration	GO:0040039	145	0.016
regulation of protein targeting	GO:1903533	3	0.015
positive regulation of neurotransmitter transport	GO:0051590	11	0.015
cellular catabolic process	GO:0044248	199	0.015
regulation of purine nucleotide metabolic process	GO:1900542	37	0.015
single organism catabolic process	GO:0044712	129	0.015
dendrite development	GO:0016358	42	0.015
purine containing compound metabolic process	GO:0072521	95	0.015
regulation of lipid metabolic process	GO:0019216	4	0.015
amine metabolic process	GO:0009308	15	0.015
cellular nitrogen compound catabolic process	GO:0044270	119	0.015
ribonucleoside metabolic process	GO:0009119	98	0.015
positive regulation of multicellular organism growth	GO:0040018	352	0.015
rna metabolic process	GO:0016070	228	0.015
axon extension	GO:0048675	37	0.015
positive regulation of catalytic activity	GO:0043085	59	0.015
gene silencing by rna	GO:0031047	143	0.015
cellular component assembly involved in morphogenesis	GO:0010927	183	0.014
developmental growth	GO:0048589	412	0.014
cell migration	GO:0016477	306	0.014
single organism behavior	GO:0044708	83	0.014
regulation of nervous system development	GO:0051960	41	0.014
regulation of nucleobase containing compound metabolic process	GO:0019219	222	0.014
regulation of cell cycle	GO:0051726	194	0.014
regulation of gene expression	GO:0010468	366	0.014
positive regulation of kinase activity	GO:0033674	19	0.014
cell division	GO:0051301	262	0.014
gamete generation	GO:0007276	461	0.014
adult behavior	GO:0030534	3	0.014
regulation of cellular ketone metabolic process	GO:0010565	3	0.014
cellular biosynthetic process	GO:0044249	315	0.014
phosphorylation	GO:0016310	116	0.014
oocyte construction	GO:0007308	2	0.014
positive regulation of synaptic transmission	GO:0050806	24	0.014
positive regulation of secretion by cell	GO:1903532	14	0.014
regulation of cellular component size	GO:0032535	40	0.013
neuromuscular junction development	GO:0007528	2	0.013
actin cytoskeleton reorganization	GO:0031532	4	0.013
positive regulation of metabolic process	GO:0009893	187	0.013
synapse organization	GO:0050808	24	0.013
response to heat	GO:0009408	50	0.013
purine nucleotide metabolic process	GO:0006163	95	0.013
ribose phosphate metabolic process	GO:0019693	99	0.013
positive regulation of intracellular protein transport	GO:0090316	2	0.013
positive regulation of nitrogen compound metabolic process	GO:0051173	134	0.013
dopamine metabolic process	GO:0042417	4	0.013
positive regulation of intracellular transport	GO:0032388	2	0.013
posttranscriptional gene silencing by rna	GO:0035194	143	0.013
positive regulation of secretion	GO:0051047	17	0.013
germ cell development	GO:0007281	351	0.013
regulation of actin filament based process	GO:0032970	22	0.013
regulation of protein import into nucleus	GO:0042306	3	0.013
cation transmembrane transport	GO:0098655	59	0.012
organic acid metabolic process	GO:0006082	47	0.012
sensory organ morphogenesis	GO:0090596	2	0.012
gene expression	GO:0010467	412	0.012
organic cyclic compound catabolic process	GO:1901361	119	0.012
striated muscle cell development	GO:0055002	157	0.012
negative regulation of response to stimulus	GO:0048585	73	0.012
muscle fiber development	GO:0048747	2	0.012
organ morphogenesis	GO:0009887	67	0.012
protein catabolic process	GO:0030163	162	0.012
anion transmembrane transport	GO:0098656	21	0.012
rna localization	GO:0006403	3	0.012
membrane depolarization	GO:0051899	1	0.012
negative regulation of cellular process	GO:0048523	239	0.012
nucleobase containing compound catabolic process	GO:0034655	114	0.012
regulation of primary metabolic process	GO:0080090	292	0.012
apoptotic process	GO:0006915	478	0.012
ribonucleoside triphosphate metabolic process	GO:0009199	87	0.012
negative regulation of multicellular organismal process	GO:0051241	236	0.012
regulation of gene expression epigenetic	GO:0040029	163	0.011
regulation of cellular component biogenesis	GO:0044087	26	0.011
cell growth	GO:0016049	44	0.011
oocyte axis specification	GO:0007309	2	0.011
myosin filament assembly	GO:0031034	138	0.011
rna interference	GO:0016246	137	0.011
regulation of cellular localization	GO:0060341	42	0.011
nucleoside metabolic process	GO:0009116	99	0.011
myosin filament organization	GO:0031033	138	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	134	0.011
regulation of exocytosis	GO:0017157	1	0.011
regulation of phosphorus metabolic process	GO:0051174	81	0.011
biosynthetic process	GO:0009058	323	0.011
organonitrogen compound catabolic process	GO:1901565	90	0.011
molting cycle collagen and cuticulin based cuticle	GO:0018996	281	0.011
positive regulation of cell migration	GO:0030335	3	0.011
mating	GO:0007618	34	0.011
organic cyclic compound biosynthetic process	GO:1901362	195	0.011
negative regulation of neurogenesis	GO:0050768	4	0.011
posttranscriptional gene silencing	GO:0016441	143	0.011
oviposition	GO:0018991	364	0.011
posttranscriptional regulation of gene expression	GO:0010608	166	0.011
positive regulation of cellular component organization	GO:0051130	34	0.011
phagocytosis	GO:0006909	115	0.011
carbohydrate derivative catabolic process	GO:1901136	82	0.011
regulation of apoptotic signaling pathway	GO:2001233	1	0.011
intraspecies interaction between organisms	GO:0051703	3	0.011
membrane invagination	GO:0010324	98	0.011
vesicle organization	GO:0016050	15	0.011
heterocycle catabolic process	GO:0046700	119	0.011
positive regulation of developmental growth	GO:0048639	354	0.011
response to abiotic stimulus	GO:0009628	152	0.010
nucleoside phosphate catabolic process	GO:1901292	77	0.010
regulation of muscle system process	GO:0090257	20	0.010
response to temperature stimulus	GO:0009266	66	0.010
muscle structure development	GO:0061061	191	0.010
single organism intracellular transport	GO:1902582	70	0.010
programmed cell death	GO:0012501	500	0.010
adult locomotory behavior	GO:0008344	1	0.010
neuron differentiation	GO:0030182	217	0.010

unc-17 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.032
	nervous system disease	DOID:863	0	0.011

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