Caenorhabditis elegans

94 known processes

mkk-4 (CELE_F42G10.2)

Protein MKK-4

mkk-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell developmentGO:00484686960.215
Rat Worm Fly
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacteriumGO:190209740.200
Worm
multi organism reproductive processGO:00447038670.193
Worm
nucleobase containing compound metabolic processGO:00061394060.172
Rat Worm
multi multicellular organism processGO:00447063900.145
Worm
gamete generationGO:00072764610.129
Worm
developmental process involved in reproductionGO:000300611650.128
Worm
positive regulation of cellular processGO:00485223320.121
regulation of biological qualityGO:00650087410.120
response to external stimulusGO:00096052890.120
Human Worm
multicellular organismal reproductive behaviorGO:00330573840.112
Worm
nucleic acid metabolic processGO:00903042990.109
Rat Worm
regulation of primary metabolic processGO:00800902920.107
regulation of metabolic processGO:00192224780.107
post embryonic developmentGO:000979121520.106
Worm
positive regulation of nucleobase containing compound metabolic processGO:00459351340.101
Rat Worm
protein metabolic processGO:00195384220.100
macromolecule localizationGO:00330367710.098
multicellular organismal reproductive processGO:00486098150.096
Worm
positive regulation of multicellular organismal processGO:00512404170.095
Worm
muscle tissue developmentGO:006053710.094
Rat
growthGO:00400075620.090
Rat Worm
localization of cellGO:00516743130.089
post embryonic organ developmentGO:00485693360.088
tissue developmentGO:00098881120.088
Rat
multicellular organism reproductionGO:00325048190.088
Worm
positive regulation of macromolecule metabolic processGO:00106041490.087
muscle structure developmentGO:00610611910.087
Rat
organic substance biosynthetic processGO:19015763230.086
Rat Worm
regulation of nucleobase containing compound metabolic processGO:00192192220.084
Rat Worm
multicellular organismal agingGO:00102598120.083
reproductive behaviorGO:00190983870.082
Worm
multi organism behaviorGO:00517053890.081
Worm
embryo development ending in birth or egg hatchingGO:000979229920.080
positive regulation of biosynthetic processGO:00098911090.076
Rat Worm
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139310.076
positive regulation of developmental processGO:00510944080.073
regulation of nitrogen compound metabolic processGO:00511712220.073
Rat Worm
organelle organizationGO:00069967830.072
Worm
lipid localizationGO:00108765730.072
p38mapk cascadeGO:003806620.071
Worm
biosynthetic processGO:00090583230.070
Rat Worm
regulation of biosynthetic processGO:00098891890.070
Rat Worm
cell deathGO:00082195470.069
Rat
positive regulation of transcription dna templatedGO:00458931020.069
Worm
negative regulation of biological processGO:00485195670.069
Worm
vulval developmentGO:00400253330.069
rna biosynthetic processGO:00327741690.068
Worm
gonad developmentGO:00084068400.068
transcription dna templatedGO:00063511680.066
Worm
neurogenesisGO:00220082360.066
Fly
positive regulation of cellular metabolic processGO:00313251780.064
lipid storageGO:00199155650.064
cell fate commitmentGO:00451651390.063
muscle organ morphogenesisGO:004864440.062
organ developmentGO:004851311020.061
Rat
gene expressionGO:00104674120.061
Worm
maintenance of locationGO:00512355800.061
determination of adult lifespanGO:00083408120.061
head developmentGO:006032210.059
regulation of post embryonic developmentGO:00485802600.059
regulation of macromolecule metabolic processGO:00602554210.057
agingGO:00075688120.055
heterocycle biosynthetic processGO:00181301870.055
Worm
regulation of multicellular organismal processGO:00512397260.055
Worm Fly
negative regulation of gene expressionGO:00106292170.055
Worm
ovipositionGO:00189913640.054
Worm
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.054
Worm
multi organism reproductive behaviorGO:00447053870.054
Worm
response to osmotic stressGO:0006970290.053
Worm
germ cell developmentGO:00072813510.052
Worm
cellular response to stressGO:00335541620.052
Zebrafish Rat Worm Fly
positive regulation of developmental growthGO:00486393540.052
positive regulation of nucleic acid templated transcriptionGO:19035081020.051
Worm
striated muscle cell differentiationGO:00511461580.051
Rat
single organism signalingGO:00447004010.051
muscle cell differentiationGO:00426921710.051
Rat
phosphorus metabolic processGO:00067932320.051
regulation of developmental growthGO:00486383890.050
organ morphogenesisGO:0009887670.049
epithelial tube morphogenesisGO:006056210.048
cell morphogenesisGO:00009021630.047
Fly
anatomical structure formation involved in morphogenesisGO:00486462500.046
cellular component morphogenesisGO:00329893180.046
Fly
regulation of cellular macromolecule biosynthetic processGO:20001121880.045
Rat Worm
cellular component movementGO:00069283880.045
regulation of macromolecule biosynthetic processGO:00105561890.045
Rat Worm
cell migrationGO:00164773060.044
cell motilityGO:00488703130.044
small molecule metabolic processGO:00442811860.044
single organism organelle organizationGO:19025895010.043
transcription from rna polymerase ii promoterGO:00063661490.043
Worm
striated muscle cell developmentGO:00550021570.043
Rat
embryo developmentGO:000979030520.043
regulation of multicellular organism growthGO:00400143730.043
cellular process involved in reproduction in multicellular organismGO:00224123510.043
Worm
regulation of vulval developmentGO:00400282480.043
cytoskeleton organizationGO:00070103390.042
positive regulation of metabolic processGO:00098931870.042
molting cycle collagen and cuticulin based cuticleGO:00189962810.042
pattern specification processGO:0007389590.042
Zebrafish
meiotic cell cycleGO:00513213350.042
Worm
nucleobase containing compound biosynthetic processGO:00346541840.042
Worm
regulation of cellular biosynthetic processGO:00313261890.042
Rat Worm
actin cytoskeleton organizationGO:00300361840.042
regulation of nematode larval developmentGO:00610622600.042
regulation of growthGO:00400084090.042
Worm
rna metabolic processGO:00160702280.041
Worm
nucleic acid templated transcriptionGO:00976591690.041
Worm
muscle cell developmentGO:00550011580.041
Rat
myofibril assemblyGO:00302391540.040
regenerationGO:003109940.040
single organism transportGO:00447654470.040
cellular protein modification processGO:00064642070.040
regulation of response to stimulusGO:00485832430.039
positive regulation of rna biosynthetic processGO:19026801020.039
Worm
cellular biosynthetic processGO:00442493150.038
Rat Worm
cellular response to abiotic stimulusGO:007121440.038
Human
regulation of rna metabolic processGO:00512521730.038
Worm
developmental growthGO:00485894120.038
Rat
negative regulation of biosynthetic processGO:0009890650.038
protein phosphorylationGO:0006468850.038
hermaphrodite genitalia developmentGO:00400357340.037
macromolecule biosynthetic processGO:00090592500.037
Rat Worm
positive regulation of growthGO:00459273690.037
sex differentiationGO:00075489090.036
posttranscriptional regulation of gene expressionGO:00106081660.036
Worm
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361820.036
protein localizationGO:00081042050.036
genitalia developmentGO:00488067410.036
regulation of gene expressionGO:00104683660.036
Worm
negative regulation of transcription dna templatedGO:0045892530.036
development of primary sexual characteristicsGO:00451378400.035
locomotionGO:004001116340.035
Worm
positive regulation of gene expressionGO:00106281120.035
Worm
positive regulation of cellular biosynthetic processGO:00313281090.035
Rat Worm
meiotic nuclear divisionGO:00071263000.035
Worm
cellular nitrogen compound biosynthetic processGO:00442711920.035
Worm
regulation of developmental processGO:00507936840.034
Fly
nervous system developmentGO:00073992530.034
Fly
neuron projection developmentGO:00311751870.034
Fly
actin filament based processGO:00300291910.033
oogenesisGO:00484772290.033
Worm
negative regulation of cellular processGO:00485232390.033
sexual reproductionGO:00199535460.032
Worm
positive regulation of nitrogen compound metabolic processGO:00511731340.032
Rat Worm
cell cycleGO:00070495260.032
Worm
regulation of cellular component organizationGO:00511282480.032
cellular protein metabolic processGO:00442672790.032
positive regulation of multicellular organism growthGO:00400183520.032
response to external biotic stimulusGO:00432071010.032
Worm
reproductive structure developmentGO:00486088500.031
sensory organ morphogenesisGO:009059620.031
signalingGO:00230524010.031
multicellular organism growthGO:00352643850.031
cell cycle processGO:00224024820.030
molting cycleGO:00423032810.030
Fly
neuron differentiationGO:00301822170.029
Fly
regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139210.029
negative regulation of cellular metabolic processGO:0031324950.029
negative regulation of nucleobase containing compound metabolic processGO:0045934630.029
cellular component assembly involved in morphogenesisGO:00109271830.029
deathGO:00162655470.029
Rat
response to chemicalGO:00422213560.029
Rat Worm
intracellular signal transductionGO:0035556960.029
response to woundingGO:000961140.028
negative regulation of nematode larval developmentGO:00610642080.028
female gamete generationGO:00072922540.028
Worm
regulation of rna biosynthetic processGO:20011411650.027
Worm
negative regulation of cellular biosynthetic processGO:0031327650.027
response to other organismGO:00517071010.027
Worm
negative regulation of developmental processGO:00510932270.027
positive regulation of neurogenesisGO:005076940.026
negative regulation of rna biosynthetic processGO:1902679530.026
negative regulation of post embryonic developmentGO:00485812080.026
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600320.026
organelle assemblyGO:00709252140.026
oxoacid metabolic processGO:0043436470.026
myosin filament assemblyGO:00310341380.025
cellular protein complex assemblyGO:00436231780.025
protein modification processGO:00362112070.025
programmed cell deathGO:00125015000.025
Rat
cell morphogenesis involved in differentiationGO:00009041120.025
negative regulation of macromolecule biosynthetic processGO:0010558650.025
cell projection morphogenesisGO:00488581480.024
Fly
positive regulation of macromolecule biosynthetic processGO:00105571090.024
Rat Worm
defense responseGO:00069522960.024
aromatic compound catabolic processGO:00194391160.024
negative regulation of vulval developmentGO:00400272060.023
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.023
macromolecular complex subunit organizationGO:00439333200.023
cellular macromolecule biosynthetic processGO:00346452470.023
Rat Worm
macromolecule modificationGO:00434122180.023
immune responseGO:00069551920.023
Worm
neuron projection guidanceGO:0097485820.023
negative regulation of multicellular organismal processGO:00512412360.023
body morphogenesisGO:00101716200.023
cellular component assemblyGO:00226072930.022
regulation of localizationGO:00328791940.022
posttranscriptional gene silencingGO:00164411430.022
Worm
defense response to bacteriumGO:0042742860.022
Worm
cellular component biogenesisGO:00440852970.022
axon developmentGO:00615641630.021
generation of neuronsGO:00486992350.021
Fly
regulation of sequence specific dna binding transcription factor activityGO:005109030.021
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.021
transportGO:000681010930.021
cell projection organizationGO:00300302310.021
Fly
regulation of cellular metabolic processGO:00313233050.021
cellular macromolecular complex assemblyGO:00346221840.021
positive regulation of post embryonic developmentGO:0048582540.021
regulation of transcription from rna polymerase ii promoterGO:00063571450.020
Worm
positive regulation of cell projection organizationGO:003134640.020
establishment of localizationGO:005123411710.020
organonitrogen compound metabolic processGO:19015641510.020
cell part morphogenesisGO:00329901520.020
Fly
cellular catabolic processGO:00442481990.020
reproductive system developmentGO:00614588500.020
response to bacteriumGO:0009617860.020
Worm
apoptotic processGO:00069154780.020
Rat
receptor mediated endocytosisGO:00068987150.020
tube developmentGO:00352951260.020
wnt signaling pathwayGO:0016055270.020
cell divisionGO:00513012620.020
regulation of cell cycle processGO:00105641450.020
regulation of cell cycleGO:00517261940.019
lamellipodium assemblyGO:003003220.019
defense response to other organismGO:00985421000.019
Worm
catabolic processGO:00090563180.019
aromatic compound biosynthetic processGO:00194381920.019
Worm
actomyosin structure organizationGO:00310321540.019
single organism reproductive processGO:004470211960.019
Worm
positive regulation of rna metabolic processGO:00512541030.019
Worm
single organism localizationGO:19025785180.019
phosphorylationGO:00163101160.019
protein complex subunit organizationGO:00718222800.018
organic cyclic compound catabolic processGO:19013611190.018
organic cyclic compound biosynthetic processGO:19013621950.018
Worm
response to organic substanceGO:00100331310.018
Rat
tissue morphogenesisGO:0048729650.018
organic acid metabolic processGO:0006082470.018
negative regulation of nitrogen compound metabolic processGO:0051172630.018
striated muscle myosin thick filament assemblyGO:00716881380.018
positive regulation of neuron differentiationGO:004566640.018
skeletal muscle organ developmentGO:006053830.018
myosin filament organizationGO:00310331380.018
axonogenesisGO:00074091020.017
regulation of apoptotic signaling pathwayGO:200123310.017
chemotaxisGO:00069351200.017
cell type specific apoptotic processGO:009728540.017
Rat
regulation of multicellular organismal developmentGO:20000263170.017
Fly
canonical wnt signaling pathwayGO:006007030.017
regulation of cellular ketone metabolic processGO:001056530.017
response to endoplasmic reticulum stressGO:0034976710.017
macromolecule catabolic processGO:00090572020.017
lamellipodium organizationGO:009758120.017
cell surface receptor signaling pathwayGO:00071661490.017
innate immune responseGO:00450871900.016
Worm
regulation of molecular functionGO:0065009890.016
regulation of reproductive processGO:2000241660.016
Worm
neuron developmentGO:00486661990.016
Fly
neuromuscular junction developmentGO:000752820.016
cellular amino acid metabolic processGO:0006520150.015
regulation of transcription dna templatedGO:00063551640.015
Worm
response to biotic stimulusGO:00096071010.015
Worm
negative regulation of rna metabolic processGO:0051253530.015
developmental cell growthGO:0048588390.015
Rat
negative regulation of nucleic acid templated transcriptionGO:1903507530.015
mesodermal cell migrationGO:000807890.015
behaviorGO:00076105270.015
Worm
posttranscriptional gene silencing by rnaGO:00351941430.015
Worm
negative regulation of cell communicationGO:0010648610.015
cell morphogenesis involved in neuron differentiationGO:00486671110.014
lipid metabolic processGO:0006629770.014
gene silencingGO:00164581430.014
Worm
hyperosmotic responseGO:0006972190.014
Worm
endocytosisGO:00068978190.014
positive regulation of neuron projection developmentGO:001097640.014
regulation of organ morphogenesisGO:200002740.014
cellular response to chemical stimulusGO:00708871290.014
Rat
apoptotic cell clearanceGO:00432771110.014
positive regulation of nematode larval developmentGO:0061063540.014
cellular lipid metabolic processGO:0044255400.014
regulation of muscle cell differentiationGO:005114710.014
digestive tract developmentGO:00485651220.014
stress activated mapk cascadeGO:0051403100.014
Zebrafish Rat Worm Fly
organic substance catabolic processGO:19015752940.014
cellular response to inorganic substanceGO:007124130.013
positive regulation of epithelial cell proliferationGO:005067910.013
cellular localizationGO:00516413600.013
negative regulation of macromolecule metabolic processGO:00106052290.013
Worm
cellular response to metal ionGO:007124830.013
gene silencing by rnaGO:00310471430.013
Worm
protein complex biogenesisGO:00702711860.013
regulation of epithelial cell differentiationGO:003085640.013
negative regulation of metabolic processGO:00098922400.013
Worm
hormone metabolic processGO:004244530.013
rna interferenceGO:00162461370.012
Worm
regulation of striated muscle contractionGO:000694240.012
macromolecular complex assemblyGO:00650031930.012
regulation of lipid metabolic processGO:001921640.012
response to heatGO:0009408500.012
regulation of cell motilityGO:2000145570.012
phagocytosisGO:00069091150.012
organophosphate metabolic processGO:00196371250.012
nucleobase containing compound catabolic processGO:00346551140.012
carboxylic acid metabolic processGO:0019752340.012
regulation of lipid transportGO:003236840.012
positive regulation of cell migrationGO:003033530.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
Zebrafish Rat Worm Fly
regulation of mitotic cell cycleGO:0007346760.012
positive regulation of cell cycleGO:0045787550.012
pigment metabolic processGO:004244020.012
response to abiotic stimulusGO:00096281520.012
Human Worm
regulation of anatomical structure morphogenesisGO:0022603510.011
heterocycle catabolic processGO:00467001190.011
cellular response to organic substanceGO:00713101190.011
Rat
protein oligomerizationGO:005125940.011
positive regulation of cell morphogenesis involved in differentiationGO:001077040.011
response to inorganic substanceGO:0010035500.011
Worm
regulation of cell proliferationGO:00421271050.011
dendrite developmentGO:0016358420.011
regulation of cell migrationGO:0030334550.011
system processGO:00030081360.011
Rat
phosphate containing compound metabolic processGO:00067962320.011
regulation of signalingGO:00230511720.011
regulation of cation channel activityGO:200125730.011
regulation of lipid biosynthetic processGO:004689010.011
transmembrane transportGO:00550851100.011
chromosome organizationGO:00512761040.011
axonal fasciculationGO:0007413790.011
regulation of cell differentiationGO:0045595810.011
single organism biosynthetic processGO:0044711910.011
neural precursor cell proliferationGO:006135190.011
defense response to gram negative bacteriumGO:0050829640.011
Worm
regulation of cellular protein metabolic processGO:0032268750.011
positive regulation of phosphate metabolic processGO:0045937560.011
tube formationGO:003514820.011
covalent chromatin modificationGO:0016569300.010
cell proliferationGO:00082831160.010
regulation of cellular amine metabolic processGO:003323800.010
protein complex assemblyGO:00064611860.010
positive regulation of vulval developmentGO:0040026520.010
regulation of protein localizationGO:0032880500.010
positive regulation of stress activated mapk cascadeGO:003287430.010
Zebrafish Rat Worm Fly
response to temperature stimulusGO:0009266660.010
Worm
cellular amine metabolic processGO:0044106150.010
inductive cell migrationGO:00400391450.010
intracellular receptor signaling pathwayGO:003052220.010
regulation of epithelial cell proliferationGO:005067810.010
membrane organizationGO:00610241350.010

mkk-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012