Caenorhabditis elegans

70 known processes

cls-2 (CELE_R107.6)

Protein CLS-2

cls-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.898
post embryonic developmentGO:000979121520.882
Worm
developmental process involved in reproductionGO:000300611650.861
Fly
embryo development ending in birth or egg hatchingGO:000979229920.839
sexual reproductionGO:00199535460.815
Fly
cell cycleGO:00070495260.744
multicellular organismal reproductive processGO:00486098150.666
Fly
single organism reproductive processGO:004470211960.649
Fly
cell cycle processGO:00224024820.648
mitotic cell cycle processGO:19030471940.614
meiotic nuclear divisionGO:00071263000.605
germ cell developmentGO:00072813510.534
Fly
gamete generationGO:00072764610.517
Fly
meiotic cell cycleGO:00513213350.499
organelle fissionGO:00482853630.477
multicellular organism reproductionGO:00325048190.472
Fly
meiotic cell cycle processGO:19030461700.471
genitalia developmentGO:00488067410.462
vesicle mediated transportGO:00161928520.433
regulation of meiotic cell cycleGO:00514451360.403
locomotionGO:004001116340.395
cytoskeleton organizationGO:00070103390.386
female gamete generationGO:00072922540.383
Fly
gonad developmentGO:00084068400.378
organelle organizationGO:00069967830.353
meiotic chromosome segregationGO:00451321390.349
microtubule based processGO:00070171820.345
centrosomal and pronuclear rotationGO:003504760.344
mitotic nuclear divisionGO:0007067890.343
fertilizationGO:0009566630.327
multi organism reproductive processGO:00447038670.302
Fly
establishment of localizationGO:005123411710.302
receptor mediated endocytosisGO:00068987150.296
transportGO:000681010930.294
organ developmentGO:004851311020.292
Fly
cellular process involved in reproduction in multicellular organismGO:00224123510.283
Fly
single organism cellular localizationGO:1902580720.247
Human Fly
sex differentiationGO:00075489090.240
reproductive system developmentGO:00614588500.238
axon developmentGO:00615641630.228
Fly
chromosome segregationGO:00070591800.227
reproductive structure developmentGO:00486088500.210
nervous system developmentGO:00073992530.204
Fly
single fertilizationGO:0007338610.201
development of primary sexual characteristicsGO:00451378400.200
oocyte axis specificationGO:000730920.190
deathGO:00162655470.186
protein complex subunit organizationGO:00718222800.181
cell divisionGO:00513012620.178
cell developmentGO:00484686960.177
Fly
oogenesisGO:00484772290.176
Fly
apoptotic processGO:00069154780.175
hermaphrodite genitalia developmentGO:00400357340.172
cellular component assemblyGO:00226072930.171
Human Fly
endocytosisGO:00068978190.170
single organism signalingGO:00447004010.169
Fly
biosynthetic processGO:00090583230.167
single organism organelle organizationGO:19025895010.164
cellular component morphogenesisGO:00329893180.160
Fly
spindle assembly involved in mitosisGO:009030760.160
organic substance biosynthetic processGO:19015763230.157
signal transductionGO:00071653170.156
Fly
regulation of meiosisGO:0040020940.147
cellular localizationGO:00516413600.145
single organism localizationGO:19025785180.142
cellular macromolecule biosynthetic processGO:00346452470.139
negative regulation of biological processGO:00485195670.137
Human Mouse Fly
oocyte differentiationGO:0009994450.135
Fly
translational initiationGO:000641320.132
digestive tract morphogenesisGO:0048546760.130
nucleobase containing compound catabolic processGO:00346551140.127
macromolecule biosynthetic processGO:00090592500.125
macromolecular complex subunit organizationGO:00439333200.125
spindle localizationGO:0051653510.118
Human Fly
regulation of cellular component organizationGO:00511282480.117
Human Mouse Fly
head developmentGO:006032210.116
response to organic substanceGO:00100331310.116
neurogenesisGO:00220082360.114
Fly
regulation of multicellular organismal processGO:00512397260.114
Worm
neuron projection guidanceGO:0097485820.113
Fly
cellular protein complex assemblyGO:00436231780.112
Human
axon guidanceGO:0007411820.110
Fly
molting cycleGO:00423032810.110
protein complex biogenesisGO:00702711860.108
Human Fly
heterocycle catabolic processGO:00467001190.106
single organism transportGO:00447654470.105
macromolecule localizationGO:00330367710.105
establishment or maintenance of cell polarityGO:0007163630.098
Human Mouse Fly
localization of cellGO:00516743130.097
Mouse Fly
cellular macromolecule localizationGO:0070727750.097
regulation of primary metabolic processGO:00800902920.093
positive regulation of cellular metabolic processGO:00313251780.093
cellular component movementGO:00069283880.093
Mouse Fly
ribose phosphate metabolic processGO:0019693990.091
homeostatic processGO:0042592510.090
programmed cell deathGO:00125015000.088
regulation of nuclear divisionGO:00517831150.088
Fly
cellular nitrogen compound catabolic processGO:00442701190.087
neuron developmentGO:00486661990.087
Fly
negative regulation of macromolecule metabolic processGO:00106052290.087
attachment of mitotic spindle microtubules to kinetochoreGO:005131560.087
organelle assemblyGO:00709252140.086
Fly
posttranscriptional regulation of gene expressionGO:00106081660.086
phosphorus metabolic processGO:00067932320.086
macromolecular complex assemblyGO:00650031930.085
Human Fly
ribonucleoside monophosphate metabolic processGO:0009161450.085
neuron projection morphogenesisGO:00488121140.083
Fly
body morphogenesisGO:00101716200.082
ovipositionGO:00189913640.081
regulation of cellular component sizeGO:0032535400.080
negative regulation of metabolic processGO:00098922400.080
aromatic compound catabolic processGO:00194391160.080
ribonucleoprotein complex assemblyGO:002261840.079
attachment of spindle microtubules to kinetochoreGO:000860880.079
multicellular organismal reproductive behaviorGO:00330573840.079
protein metabolic processGO:00195384220.077
ribonucleotide catabolic processGO:0009261750.076
cellular response to chemical stimulusGO:00708871290.074
digestive system developmentGO:00551231220.074
maintenance of locationGO:00512355800.074
cellular biosynthetic processGO:00442493150.073
cellular response to organic substanceGO:00713101190.071
lipid storageGO:00199155650.070
purine containing compound catabolic processGO:0072523750.070
organic cyclic compound catabolic processGO:19013611190.070
cell morphogenesis involved in neuron differentiationGO:00486671110.068
Fly
regulation of cell divisionGO:00513021420.066
Fly
cell migrationGO:00164773060.065
Mouse Fly
lipid localizationGO:00108765730.065
nucleoside triphosphate catabolic processGO:0009143720.063
maintenance of protein locationGO:0045185150.062
purine nucleoside catabolic processGO:0006152750.060
inductive cell migrationGO:00400391450.060
cell motilityGO:00488703130.059
Mouse Fly
organonitrogen compound metabolic processGO:19015641510.058
maintenance of protein location in cellGO:0032507120.057
cellular protein metabolic processGO:00442672790.056
regulation of biological qualityGO:00650087410.056
defense responseGO:00069522960.056
multicellular organismal agingGO:00102598120.055
cell projection morphogenesisGO:00488581480.055
Fly
cytokinesisGO:0000910800.054
generation of neuronsGO:00486992350.054
Fly
neuron projection developmentGO:00311751870.054
Fly
microtubule cytoskeleton organization involved in mitosisGO:1902850120.054
cellular macromolecular complex assemblyGO:00346221840.054
Human
purine ribonucleotide catabolic processGO:0009154750.054
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.054
small molecule metabolic processGO:00442811860.054
intracellular signal transductionGO:0035556960.053
Fly
digestive tract developmentGO:00485651220.052
nucleobase containing compound metabolic processGO:00061394060.051
nucleoside catabolic processGO:0009164780.051
cell deathGO:00082195470.051
tube developmentGO:00352951260.050
tube morphogenesisGO:0035239790.050
nucleic acid metabolic processGO:00903042990.050
positive regulation of cellular processGO:00485223320.049
phagocytosisGO:00069091150.049
chemotaxisGO:00069351200.049
Fly
signalingGO:00230524010.049
Fly
regulation of growthGO:00400084090.049
Worm
purine nucleoside triphosphate metabolic processGO:0009144870.049
gene silencingGO:00164581430.048
purine nucleotide catabolic processGO:0006195750.047
negative regulation of cellular biosynthetic processGO:0031327650.047
response to chemicalGO:00422213560.046
Fly
regulation of intracellular signal transductionGO:1902531770.045
Fly
macromolecule modificationGO:00434122180.045
nucleotide metabolic processGO:00091171080.045
protein complex assemblyGO:00064611860.044
Human Fly
actin cytoskeleton organizationGO:00300361840.044
regulation of cellular protein metabolic processGO:0032268750.044
positive regulation of growthGO:00459273690.043
Worm
regulation of gene expression epigeneticGO:00400291630.043
cell type specific apoptotic processGO:009728540.043
cellular protein localizationGO:0034613750.043
glycosyl compound catabolic processGO:1901658790.042
regulation of multicellular organismal developmentGO:20000263170.042
ribonucleoside triphosphate metabolic processGO:0009199870.042
protein phosphorylationGO:0006468850.042
sensory organ morphogenesisGO:009059620.042
nucleus localizationGO:0051647550.042
regulation of anatomical structure sizeGO:0090066460.041
phosphate containing compound metabolic processGO:00067962320.041
agingGO:00075688120.041
response to external stimulusGO:00096052890.041
Fly
negative regulation of developmental processGO:00510932270.041
Fly
determination of adult lifespanGO:00083408120.041
negative regulation of multicellular organismal processGO:00512412360.040
regulation of nucleobase containing compound metabolic processGO:00192192220.040
cell projection organizationGO:00300302310.040
Fly
small gtpase mediated signal transductionGO:0007264320.040
Fly
regulation of cell cycleGO:00517261940.040
Fly
protein localizationGO:00081042050.040
cellular component biogenesisGO:00440852970.039
Human Fly
mitotic spindle organizationGO:0007052810.039
negative regulation of vulval developmentGO:00400272060.039
multi organism reproductive behaviorGO:00447053870.038
establishment of spindle localizationGO:0051293510.037
Human Fly
neuron differentiationGO:00301822170.037
Fly
carbohydrate derivative metabolic processGO:19011351410.037
regulation of cell communicationGO:00106461760.036
Fly
membrane organizationGO:00610241350.036
myosin filament assemblyGO:00310341380.036
positive regulation of multicellular organismal processGO:00512404170.036
Worm
molting cycle collagen and cuticulin based cuticleGO:00189962810.036
regulation of protein localizationGO:0032880500.036
purine ribonucleotide metabolic processGO:0009150950.036
oocyte developmentGO:0048599440.036
Fly
developmental maturationGO:0021700260.035
Fly
response to abiotic stimulusGO:00096281520.035
negative regulation of cell cycleGO:0045786530.035
growthGO:00400075620.035
Worm
cellular catabolic processGO:00442481990.035
nucleoside triphosphate metabolic processGO:0009141870.035
positive regulation of developmental growthGO:00486393540.035
Worm
regulation of developmental growthGO:00486383890.035
Worm
actin filament based processGO:00300291910.034
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.034
purine ribonucleoside catabolic processGO:0046130750.034
secretionGO:00469031470.033
cell cycle switching mitotic to meiotic cell cycleGO:0051728350.032
catabolic processGO:00090563180.032
purine ribonucleoside triphosphate metabolic processGO:0009205870.032
cellular response to abiotic stimulusGO:007121440.032
purine ribonucleoside triphosphate catabolic processGO:0009207720.031
pronuclear migrationGO:0035046510.031
aromatic compound biosynthetic processGO:00194381920.031
negative regulation of macromolecule biosynthetic processGO:0010558650.031
posttranscriptional gene silencing by rnaGO:00351941430.031
positive regulation of catabolic processGO:0009896380.031
negative regulation of cellular processGO:00485232390.031
Human Mouse Fly
positive regulation of developmental processGO:00510944080.031
Worm
regulation of phosphate metabolic processGO:0019220810.030
cellular response to stressGO:00335541620.030
anatomical structure formation involved in morphogenesisGO:00486462500.030
Fly
regulation of programmed cell deathGO:0043067500.030
translationGO:0006412370.030
rna interferenceGO:00162461370.030
striated muscle cell developmentGO:00550021570.029
taxisGO:00423301280.029
Fly
multi organism behaviorGO:00517053890.029
behaviorGO:00076105270.029
rna splicing via transesterification reactionsGO:000037580.029
regulation of biosynthetic processGO:00098891890.029
establishment of cell polarityGO:0030010460.029
Human
purine nucleoside monophosphate metabolic processGO:0009126430.029
regulation of signal transductionGO:00099661350.029
Fly
regulation of localizationGO:00328791940.028
cell proliferationGO:00082831160.028
muscle tissue developmentGO:006053710.028
chromosome organization involved in meiosisGO:0070192250.027
actomyosin structure organizationGO:00310321540.027
negative regulation of gene expressionGO:00106292170.027
regulation of cellular biosynthetic processGO:00313261890.027
positive regulation of phosphate metabolic processGO:0045937560.026
developmental growthGO:00485894120.026
Worm
nucleotide catabolic processGO:0009166770.026
establishment of nucleus localizationGO:0040023550.026
spermatogenesisGO:0007283410.026
female meiotic divisionGO:0007143170.026
organic substance catabolic processGO:19015752940.026
negative regulation of cellular protein metabolic processGO:0032269270.026
positive regulation of phosphorus metabolic processGO:0010562560.026
oocyte constructionGO:000730820.026
Fly
purine nucleoside triphosphate catabolic processGO:0009146720.025
regulation of phosphorus metabolic processGO:0051174810.025
organophosphate catabolic processGO:0046434810.025
nucleobase containing small molecule metabolic processGO:00550861150.025
regulation of macromolecule metabolic processGO:00602554210.025
regulation of cell proliferationGO:00421271050.025
gene expressionGO:00104674120.024
purine nucleoside monophosphate catabolic processGO:0009128280.024
ribonucleoside triphosphate catabolic processGO:0009203720.024
establishment of localization in cellGO:00516493180.024
reproductive behaviorGO:00190983870.024
response to endoplasmic reticulum stressGO:0034976710.024
organonitrogen compound catabolic processGO:1901565900.024
cell part morphogenesisGO:00329901520.024
Fly
regulation of cell morphogenesis involved in differentiationGO:0010769290.023
system processGO:00030081360.023
positive regulation of nucleotide catabolic processGO:0030813280.023
nucleoside monophosphate metabolic processGO:0009123460.023
muscle cell developmentGO:00550011580.023
striated muscle myosin thick filament assemblyGO:00716881380.023
posttranscriptional gene silencingGO:00164411430.023
tissue morphogenesisGO:0048729650.023
cellular protein modification processGO:00064642070.023
regulation of developmental processGO:00507936840.023
Worm Fly
innate immune responseGO:00450871900.022
negative regulation of response to stimulusGO:0048585730.022
Fly
ribonucleoside metabolic processGO:0009119980.022
gene silencing by rnaGO:00310471430.022
pole plasm assemblyGO:000731520.022
purine nucleoside metabolic processGO:0042278920.022
multicellular organism growthGO:00352643850.022
Worm
regulation of rna biosynthetic processGO:20011411650.022
mitotic sister chromatid segregationGO:0000070380.022
kinetochore organizationGO:005138370.022
organophosphate metabolic processGO:00196371250.022
single organism catabolic processGO:00447121290.021
male sex differentiationGO:0046661860.021
ribonucleotide metabolic processGO:0009259990.021
positive regulation of metabolic processGO:00098931870.021
regulation of cellular metabolic processGO:00313233050.021
mitotic g2 m transition checkpointGO:004481810.021
tissue developmentGO:00098881120.021
nuclear migrationGO:0007097540.021
rna metabolic processGO:00160702280.021
regulation of nematode larval developmentGO:00610622600.021
male gamete generationGO:0048232410.021
cell morphogenesisGO:00009021630.021
Fly
regulation of molecular functionGO:0065009890.020
negative regulation of mitotic cell cycleGO:0045930420.020
regulation of neuron differentiationGO:0045664400.020
establishment of organelle localizationGO:00516561230.020
purine nucleotide metabolic processGO:0006163950.020
striated muscle cell differentiationGO:00511461580.020
spindle organizationGO:0007051920.020
nucleoside phosphate catabolic processGO:1901292770.020
regulation of response to stimulusGO:00485832430.019
Fly
regulation of signalingGO:00230511720.019
Fly
polar body extrusion after meiotic divisionsGO:0040038140.019
negative regulation of rna metabolic processGO:0051253530.019
regulation of metabolic processGO:00192224780.019
single organism biosynthetic processGO:0044711910.019
establishment of mitotic spindle orientationGO:0000132280.019
myosin filament organizationGO:00310331380.018
cell surface receptor signaling pathwayGO:00071661490.018
nucleoside metabolic processGO:0009116990.018
regulation of multicellular organism growthGO:00400143730.018
Worm
muscle cell differentiationGO:00426921710.018
regulation of apoptotic signaling pathwayGO:200123310.018
mrna splice site selectionGO:000637610.018
maturation of 5 8s rrnaGO:000046010.018
transcription dna templatedGO:00063511680.018
organic substance transportGO:00717021130.018
regulation of cellular catabolic processGO:0031329510.017
positive regulation of cellular catabolic processGO:0031331350.017
establishment of spindle orientationGO:0051294340.017
Human
neuron recognitionGO:0008038830.017
epithelium developmentGO:0060429680.017
microtubule anchoringGO:003445380.017
positive regulation of catalytic activityGO:0043085590.017
purine ribonucleoside monophosphate catabolic processGO:0009169280.017
phosphorylationGO:00163101160.017
positive regulation of signal transductionGO:0009967400.017
ras protein signal transductionGO:0007265310.017
Fly
purine ribonucleoside monophosphate metabolic processGO:0009167430.017
purine ribonucleoside metabolic processGO:0046128920.017
nucleoside phosphate metabolic processGO:00067531080.017
axonogenesisGO:00074091020.017
Fly
regulation of protein metabolic processGO:0051246810.017
ribonucleoside catabolic processGO:0042454770.017
muscle structure developmentGO:00610611910.017
negative regulation of protein metabolic processGO:0051248270.017
negative regulation of gene expression epigeneticGO:004581420.016
carbohydrate derivative catabolic processGO:1901136820.016
cell recognitionGO:0008037850.016
myofibril assemblyGO:00302391540.016
negative regulation of cellular component organizationGO:0051129330.016
Human Mouse Fly
mrna metabolic processGO:0016071310.016
regulation of catalytic activityGO:0050790780.016
negative regulation of nematode larval developmentGO:00610642080.016
skeletal muscle organ developmentGO:006053830.016
negative regulation of nitrogen compound metabolic processGO:0051172630.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.016
positive regulation of intracellular transportGO:003238820.015
negative regulation of cellular protein catabolic processGO:190336340.015
positive regulation of meiotic cell cycleGO:0051446470.015
regulation of nucleic acid templated transcriptionGO:19035061650.015
regulation of cell sizeGO:0008361300.015
negative regulation of apoptotic processGO:0043066170.015
rna biosynthetic processGO:00327741690.015
negative regulation of translationGO:0017148100.014
organelle localizationGO:00516401270.014
single organism membrane organizationGO:0044802350.014
positive regulation of neurogenesisGO:005076940.014
canonical wnt signaling pathwayGO:006007030.014
protein transportGO:0015031450.014
rna catabolic processGO:0006401210.014
regulation of cell deathGO:0010941650.014
protein oligomerizationGO:005125940.014
negative regulation of cellular metabolic processGO:0031324950.014
regulation of mitotic cell cycleGO:0007346760.014
Fly
positive regulation of signalingGO:0023056660.014
regulation of apoptotic processGO:0042981360.014
meiosis iGO:0007127190.014
heterocycle biosynthetic processGO:00181301870.014
positive regulation of organ growthGO:004662240.014
protein targeting to mitochondrionGO:000662620.014
multi multicellular organism processGO:00447063900.014
glycosyl compound metabolic processGO:19016571000.013
establishment of protein localizationGO:0045184500.013
transmembrane transportGO:00550851100.013
mrna splicing via spliceosomeGO:000039880.013
embryonic morphogenesisGO:00485981520.013
dauer larval developmentGO:0040024920.013
actin cytoskeleton reorganizationGO:003153240.013
protein modification processGO:00362112070.013
positive regulation of multicellular organism growthGO:00400183520.013
Worm
rrna metabolic processGO:001607230.013
negative regulation of nucleic acid templated transcriptionGO:1903507530.013
negative regulation of cell communicationGO:0010648610.013
Fly
positive regulation of cell communicationGO:0010647690.013
atp metabolic processGO:0046034420.013
positive regulation of nitrogen compound metabolic processGO:00511731340.012
organic acid metabolic processGO:0006082470.012
immune responseGO:00069551920.012
neuron apoptotic processGO:005140240.012
collagen and cuticulin based cuticle developmentGO:0040002990.012
regulation of neuron projection developmentGO:0010975310.012
germline cell cycle switching mitotic to meiotic cell cycleGO:0051729350.012
regulation of organ morphogenesisGO:200002740.012
phagocytosis engulfmentGO:0006911980.012
actin filament based movementGO:003004840.012
protein modification by small protein conjugation or removalGO:0070647400.012
response to woundingGO:000961140.012
establishment of mitotic spindle localizationGO:0040001410.012
Fly
cuticle developmentGO:00423351000.012
establishment of protein localization to membraneGO:009015030.012
positive regulation of phosphorylationGO:0042327270.011
negative regulation of biosynthetic processGO:0009890650.011
positive regulation of protein transportGO:005122240.011
establishment of protein localization to mitochondrionGO:007265520.011
vulval developmentGO:00400253330.011
negative regulation of nucleobase containing compound metabolic processGO:0045934630.011
membrane invaginationGO:0010324980.011
axonal fasciculationGO:0007413790.011
regulation of translationGO:0006417190.011
ribosome biogenesisGO:004225440.011
nucleus organizationGO:0006997380.010
regulation of rna metabolic processGO:00512521730.010
regulation of transportGO:0051049910.010
regulation of epithelial cell differentiationGO:003085640.010
cellular response to nitrogen compoundGO:1901699240.010
mrna processingGO:0006397130.010
regulation of vulval developmentGO:00400282480.010
cell maturationGO:0048469260.010
Fly
positive regulation of response to stimulusGO:0048584550.010

cls-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.021