Caenorhabditis elegans

27 known processes

tol-1 (CELE_C07F11.1)

Protein TOL-1

tol-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979121520.551
apoptotic processGO:00069154780.481
programmed cell deathGO:00125015000.427
embryo development ending in birth or egg hatchingGO:000979229920.415
deathGO:00162655470.411
cell developmentGO:00484686960.402
Fly
locomotionGO:004001116340.388
Fly
embryo developmentGO:000979030520.376
cell deathGO:00082195470.363
positive regulation of metabolic processGO:00098931870.359
Mouse Fly
signalingGO:00230524010.335
Mouse
regulation of metabolic processGO:00192224780.322
Mouse Fly
regulation of macromolecule metabolic processGO:00602554210.310
Mouse
organelle organizationGO:00069967830.299
chemotaxisGO:00069351200.292
Fly
protein metabolic processGO:00195384220.291
Mouse
transportGO:000681010930.283
regulation of primary metabolic processGO:00800902920.277
Mouse
single organism signalingGO:00447004010.276
Mouse
aromatic compound biosynthetic processGO:00194381920.275
Mouse
establishment of localizationGO:005123411710.270
regulation of rna metabolic processGO:00512521730.268
Mouse
gonad developmentGO:00084068400.268
cellular component movementGO:00069283880.246
negative regulation of biological processGO:00485195670.243
Mouse
endocytosisGO:00068978190.242
single organism reproductive processGO:004470211960.238
development of primary sexual characteristicsGO:00451378400.238
multi organism reproductive processGO:00447038670.237
nucleic acid templated transcriptionGO:00976591690.233
Mouse
determination of adult lifespanGO:00083408120.228
agingGO:00075688120.218
positive regulation of cellular processGO:00485223320.215
Mouse Fly
regulation of cellular metabolic processGO:00313233050.213
Mouse Fly
nucleobase containing compound biosynthetic processGO:00346541840.212
Mouse
positive regulation of cellular metabolic processGO:00313251780.201
Mouse Fly
multicellular organismal reproductive processGO:00486098150.200
developmental process involved in reproductionGO:000300611650.198
macromolecule localizationGO:00330367710.193
regulation of multicellular organismal processGO:00512397260.188
Mouse Fly
protein modification processGO:00362112070.187
organ developmentGO:004851311020.187
Fly
neurogenesisGO:00220082360.181
Fly
multicellular organism reproductionGO:00325048190.178
transcription dna templatedGO:00063511680.178
Mouse
single organism localizationGO:19025785180.174
cellular protein modification processGO:00064642070.172
head developmentGO:006032210.171
macromolecule modificationGO:00434122180.168
multicellular organismal reproductive behaviorGO:00330573840.163
negative regulation of cellular processGO:00485232390.163
tube developmentGO:00352951260.162
vesicle mediated transportGO:00161928520.160
nucleic acid metabolic processGO:00903042990.158
Mouse
muscle tissue developmentGO:006053710.157
neuron differentiationGO:00301822170.155
Fly
single organism transportGO:00447654470.154
ovipositionGO:00189913640.152
regulation of biological qualityGO:00650087410.152
Mouse
cell projection organizationGO:00300302310.150
cellular biosynthetic processGO:00442493150.150
Mouse Fly
regulation of response to stimulusGO:00485832430.148
Mouse Fly
protein localizationGO:00081042050.147
positive regulation of rna biosynthetic processGO:19026801020.147
Mouse
behaviorGO:00076105270.147
heterocycle biosynthetic processGO:00181301870.146
Mouse
organelle fissionGO:00482853630.141
regulation of molecular functionGO:0065009890.140
Mouse
regulation of nitrogen compound metabolic processGO:00511712220.140
Mouse Fly
nucleobase containing compound metabolic processGO:00061394060.137
Mouse
axon developmentGO:00615641630.136
cell motilityGO:00488703130.135
multicellular organismal agingGO:00102598120.133
negative regulation of post embryonic developmentGO:00485812080.131
receptor mediated endocytosisGO:00068987150.128
cell part morphogenesisGO:00329901520.126
regulation of developmental processGO:00507936840.125
Fly
regulation of transcription from rna polymerase ii promoterGO:00063571450.124
Mouse
localization of cellGO:00516743130.124
regulation of post embryonic developmentGO:00485802600.123
regulation of macromolecule biosynthetic processGO:00105561890.122
Mouse
phosphorus metabolic processGO:00067932320.121
Mouse
rna metabolic processGO:00160702280.121
Mouse
meiotic cell cycleGO:00513213350.121
positive regulation of nitrogen compound metabolic processGO:00511731340.119
Mouse Fly
ovulationGO:0030728330.117
cell cycleGO:00070495260.116
Fly
neuron projection developmentGO:00311751870.113
regulation of developmental growthGO:00486383890.112
organic cyclic compound biosynthetic processGO:19013621950.111
Mouse
regulation of nematode larval developmentGO:00610622600.111
generation of neuronsGO:00486992350.110
Fly
gamete generationGO:00072764610.108
cellular nitrogen compound biosynthetic processGO:00442711920.107
Mouse Fly
positive regulation of biosynthetic processGO:00098911090.107
Mouse Fly
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.106
Mouse
cellular localizationGO:00516413600.103
positive regulation of transcription dna templatedGO:00458931020.101
Mouse
neuron developmentGO:00486661990.100
Fly
positive regulation of developmental processGO:00510944080.100
nervous system developmentGO:00073992530.100
Fly
mitotic cell cycle processGO:19030471940.099
Fly
regulation of signalingGO:00230511720.098
Mouse
sexual reproductionGO:00199535460.098
positive regulation of neuron differentiationGO:004566640.098
reproductive system developmentGO:00614588500.098
organic substance biosynthetic processGO:19015763230.098
Mouse Fly
anatomical structure formation involved in morphogenesisGO:00486462500.096
response to chemicalGO:00422213560.096
Mouse Fly
sex differentiationGO:00075489090.096
neuron projection morphogenesisGO:00488121140.096
signal transductionGO:00071653170.094
Mouse
biosynthetic processGO:00090583230.092
Mouse Fly
developmental growthGO:00485894120.091
meiotic nuclear divisionGO:00071263000.090
regulation of cellular macromolecule biosynthetic processGO:20001121880.090
Mouse
tissue developmentGO:00098881120.089
gastrulationGO:0007369580.089
positive regulation of neurogenesisGO:005076940.089
cell migrationGO:00164773060.087
cell cycle processGO:00224024820.087
Fly
cellular macromolecule biosynthetic processGO:00346452470.087
Mouse
regulation of catalytic activityGO:0050790780.087
growthGO:00400075620.086
protein complex subunit organizationGO:00718222800.086
phosphorylationGO:00163101160.086
Mouse
lipid localizationGO:00108765730.084
cell divisionGO:00513012620.083
Fly
cellular component assemblyGO:00226072930.082
Fly
multi organism behaviorGO:00517053890.081
positive regulation of signalingGO:0023056660.081
Mouse
regulation of vulval developmentGO:00400282480.080
positive regulation of multicellular organismal processGO:00512404170.079
Mouse
regulation of mapk cascadeGO:0043408230.079
Mouse
cell morphogenesisGO:00009021630.079
taxisGO:00423301280.078
Fly
response to abiotic stimulusGO:00096281520.078
reproductive behaviorGO:00190983870.078
cellular protein metabolic processGO:00442672790.078
protein complex assemblyGO:00064611860.078
cellular response to stressGO:00335541620.077
Mouse
multi multicellular organism processGO:00447063900.076
dauer larval developmentGO:0040024920.075
genitalia developmentGO:00488067410.075
multi organism reproductive behaviorGO:00447053870.074
regulation of biosynthetic processGO:00098891890.074
Mouse Fly
positive regulation of macromolecule metabolic processGO:00106041490.072
Mouse
lipid storageGO:00199155650.071
maintenance of locationGO:00512355800.070
intracellular signal transductionGO:0035556960.070
Mouse
single organism behaviorGO:0044708830.070
digestive system developmentGO:00551231220.070
response to external stimulusGO:00096052890.070
skeletal muscle organ developmentGO:006053830.069
actin filament based processGO:00300291910.069
positive regulation of nucleic acid templated transcriptionGO:19035081020.066
Mouse
negative regulation of vulval developmentGO:00400272060.066
regulation of phosphorus metabolic processGO:0051174810.066
Mouse
digestive tract developmentGO:00485651220.066
gene expressionGO:00104674120.065
Mouse
negative regulation of multicellular organismal processGO:00512412360.065
Mouse
regulation of cellular biosynthetic processGO:00313261890.065
Mouse Fly
negative regulation of nematode larval developmentGO:00610642080.065
negative regulation of metabolic processGO:00098922400.065
regulation of multicellular organismal developmentGO:20000263170.064
female gamete generationGO:00072922540.064
regulation of transcription dna templatedGO:00063551640.063
Mouse
cell morphogenesis involved in neuron differentiationGO:00486671110.063
rna biosynthetic processGO:00327741690.063
Mouse
multicellular organism growthGO:00352643850.062
regulation of cell communicationGO:00106461760.061
Mouse
transcription from rna polymerase ii promoterGO:00063661490.061
Mouse
regulation of rna biosynthetic processGO:20011411650.061
Mouse
cellular component morphogenesisGO:00329893180.060
axon guidanceGO:0007411820.060
cellular response to chemical stimulusGO:00708871290.060
positive regulation of developmental growthGO:00486393540.059
regulation of nucleic acid templated transcriptionGO:19035061650.059
Mouse
establishment of localization in cellGO:00516493180.058
regulation of locomotionGO:00400121610.057
positive regulation of nucleobase containing compound metabolic processGO:00459351340.057
Mouse
regulation of growthGO:00400084090.055
mapk cascadeGO:0000165310.055
Mouse
positive regulation of growthGO:00459273690.054
regulation of reproductive processGO:2000241660.054
cellular process involved in reproduction in multicellular organismGO:00224123510.053
embryonic morphogenesisGO:00485981520.053
actin cytoskeleton organizationGO:00300361840.053
positive regulation of gene expressionGO:00106281120.052
Mouse
nitrogen compound transportGO:0071705490.052
single organism organelle organizationGO:19025895010.050
protein phosphorylationGO:0006468850.050
regulation of cell divisionGO:00513021420.050
regulation of multicellular organism growthGO:00400143730.048
cytoskeleton organizationGO:00070103390.048
axonogenesisGO:00074091020.048
cell morphogenesis involved in differentiationGO:00009041120.047
macromolecule biosynthetic processGO:00090592500.047
Mouse
sensory organ morphogenesisGO:009059620.047
tube morphogenesisGO:0035239790.046
establishment or maintenance of cell polarityGO:0007163630.045
negative regulation of developmental processGO:00510932270.045
muscle structure developmentGO:00610611910.045
macromolecular complex subunit organizationGO:00439333200.044
regulation of behaviorGO:0050795970.044
cellular response to organic substanceGO:00713101190.044
digestive tract morphogenesisGO:0048546760.043
regulation of localizationGO:00328791940.043
regulation of multi organism processGO:0043900690.043
Fly
response to organic substanceGO:00100331310.043
Mouse
positive regulation of multicellular organism growthGO:00400183520.043
muscle organ developmentGO:0007517260.043
cell projection morphogenesisGO:00488581480.042
regulation of intracellular signal transductionGO:1902531770.042
Mouse
regulation of signal transductionGO:00099661350.042
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192220.040
Mouse
positive regulation of rna metabolic processGO:00512541030.040
Mouse
epithelial cell proliferationGO:005067310.039
striated muscle cell developmentGO:00550021570.039
organ morphogenesisGO:0009887670.039
positive regulation of cellular biosynthetic processGO:00313281090.038
Mouse Fly
cell type specific apoptotic processGO:009728540.038
regulation of epithelial cell proliferationGO:005067810.038
tissue morphogenesisGO:0048729650.037
vulval developmentGO:00400253330.036
ion transportGO:00068111130.036
regulation of gene expressionGO:00104683660.036
Mouse
cellular protein localizationGO:0034613750.035
defense responseGO:00069522960.035
post embryonic organ developmentGO:00485693360.035
negative regulation of macromolecule metabolic processGO:00106052290.035
positive regulation of cell projection organizationGO:003134640.034
oogenesisGO:00484772290.034
oocyte developmentGO:0048599440.034
reproductive structure developmentGO:00486088500.034
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.034
cellular component biogenesisGO:00440852970.034
Fly
cell surface receptor signaling pathwayGO:00071661490.034
positive regulation of macromolecule biosynthetic processGO:00105571090.033
Mouse
positive regulation of neuron projection developmentGO:001097640.032
cellular component assembly involved in morphogenesisGO:00109271830.032
regulation of cell deathGO:0010941650.032
regulation of phosphate metabolic processGO:0019220810.032
Mouse
regulation of protein serine threonine kinase activityGO:0071900180.031
regulation of neuron differentiationGO:0045664400.031
positive regulation of stress activated mapk cascadeGO:003287430.031
Mouse
neuron recognitionGO:0008038830.031
Fly
enzyme linked receptor protein signaling pathwayGO:0007167500.031
organelle localizationGO:00516401270.031
positive regulation of molecular functionGO:0044093610.031
Mouse
phosphate containing compound metabolic processGO:00067962320.030
Mouse
myofibril assemblyGO:00302391540.030
hermaphrodite genitalia developmentGO:00400357340.030
organelle assemblyGO:00709252140.029
positive regulation of locomotionGO:0040017420.029
cell cell signalingGO:00072671180.029
cell recognitionGO:0008037850.029
Fly
chromatin organizationGO:0006325320.029
oocyte differentiationGO:0009994450.028
positive regulation of epithelial cell proliferationGO:005067910.027
regulation of cellular component organizationGO:00511282480.027
signal transduction by phosphorylationGO:0023014310.027
Mouse
regulation of cell cycle processGO:00105641450.027
stress activated mapk cascadeGO:0051403100.027
Mouse
molting cycleGO:00423032810.026
response to woundingGO:000961140.026
Mouse
meiotic chromosome segregationGO:00451321390.025
meiotic cell cycle processGO:19030461700.025
system processGO:00030081360.025
Mouse
posttranscriptional gene silencingGO:00164411430.025
gene silencingGO:00164581430.025
body morphogenesisGO:00101716200.025
regulation of gene expression epigeneticGO:00400291630.025
membrane invaginationGO:0010324980.025
regulation of response to woundingGO:190303410.024
Mouse
muscle cell differentiationGO:00426921710.024
chromosome organizationGO:00512761040.024
negative regulation of cell communicationGO:0010648610.024
cation transportGO:0006812780.024
phagocytosisGO:00069091150.024
regulation of neuron projection developmentGO:0010975310.024
regulation of sequence specific dna binding transcription factor activityGO:005109030.023
Mouse
immune responseGO:00069551920.023
Mouse Fly
regulation of programmed cell deathGO:0043067500.023
macromolecular complex assemblyGO:00650031930.023
organonitrogen compound metabolic processGO:19015641510.022
Fly
germ cell developmentGO:00072813510.022
regulation of cellular component movementGO:0051270620.022
long term memoryGO:000761620.022
memoryGO:000761330.022
neurological system processGO:0050877530.022
neuromuscular junction developmentGO:000752820.022
negative regulation of signal transductionGO:0009968600.021
positive regulation of phosphorus metabolic processGO:0010562560.021
Mouse
membrane organizationGO:00610241350.021
epithelium developmentGO:0060429680.021
myosin filament assemblyGO:00310341380.021
negative regulation of signalingGO:0023057610.021
striated muscle myosin thick filament assemblyGO:00716881380.021
striated muscle cell differentiationGO:00511461580.021
establishment of protein localization to membraneGO:009015030.021
synaptic transmissionGO:00072681060.020
axis specificationGO:0009798230.020
Fly
small molecule metabolic processGO:00442811860.020
regulation of transferase activityGO:0051338310.020
protein catabolic processGO:00301631620.020
establishment of organelle localizationGO:00516561230.020
adult behaviorGO:003053430.020
cellular response to abiotic stimulusGO:007121440.020
positive regulation of catalytic activityGO:0043085590.019
negative regulation of gene expressionGO:00106292170.019
apoptotic cell clearanceGO:00432771110.019
neurotransmitter transportGO:0006836320.019
myosin filament organizationGO:00310331380.019
regulation of cellular protein metabolic processGO:0032268750.019
cellular protein complex assemblyGO:00436231780.018
neuron projection guidanceGO:0097485820.018
positive regulation of apoptotic processGO:0043065170.018
positive regulation of signal transductionGO:0009967400.018
Mouse
posttranscriptional gene silencing by rnaGO:00351941430.018
regulation of stress activated mapk cascadeGO:003287250.018
Mouse
organic substance transportGO:00717021130.018
cellular macromolecule localizationGO:0070727750.018
cell fate commitmentGO:00451651390.018
regulation of cytoplasmic transportGO:190364930.018
regulation of protein metabolic processGO:0051246810.018
Mouse
regulation of nervous system developmentGO:0051960410.017
regulation of apoptotic processGO:0042981360.017
asymmetric protein localizationGO:0008105350.017
regulation of cell cycleGO:00517261940.017
actomyosin structure organizationGO:00310321540.017
negative regulation of cellular metabolic processGO:0031324950.017
positive regulation of phosphate metabolic processGO:0045937560.017
Mouse
regulation of cell projection organizationGO:0031344380.017
cytoskeleton dependent cytokinesisGO:0061640350.017
Fly
positive regulation of cell deathGO:0010942380.017
establishment of cell polarityGO:0030010460.017
regulation of cell differentiationGO:0045595810.016
Fly
asymmetric cell divisionGO:0008356360.016
regulation of cellular response to stressGO:0080135190.016
Mouse
cell proliferationGO:00082831160.016
Fly
tube formationGO:003514820.016
regulation of cell proliferationGO:00421271050.016
regulation of transportGO:0051049910.016
engulfment of apoptotic cellGO:0043652940.016
negative regulation of gene expression epigeneticGO:004581420.016
protein complex biogenesisGO:00702711860.016
phagocytosis engulfmentGO:0006911980.016
synaptic growth at neuromuscular junctionGO:005112410.016
response to oxygen containing compoundGO:1901700440.016
inductive cell migrationGO:00400391450.016
regulation of ovipositionGO:0046662430.016
neuron apoptotic processGO:005140240.016
covalent chromatin modificationGO:0016569300.015
pigment metabolic processGO:004244020.015
positive regulation of intracellular transportGO:003238820.015
regulation of cell morphogenesisGO:0022604400.015
regulation of apoptotic signaling pathwayGO:200123310.015
rna interferenceGO:00162461370.015
regulation of map kinase activityGO:0043405130.015
regulation of jun kinase activityGO:004350630.015
muscle cell developmentGO:00550011580.015
cellular response to dna damage stimulusGO:0006974410.015
chromosome segregationGO:00070591800.015
jnk cascadeGO:000725480.015
Mouse
regulation of response to stressGO:0080134280.015
Mouse Fly
rna localizationGO:000640330.015
regulation of neurogenesisGO:0050767400.015
developmental cell growthGO:0048588390.015
protein oligomerizationGO:005125940.015
golgi vesicle transportGO:004819330.014
cell substrate adhesionGO:003158910.014
lipid metabolic processGO:0006629770.014
intracellular receptor signaling pathwayGO:003052220.014
positive regulation of cell migrationGO:003033530.014
regulation of phosphorylationGO:0042325450.014
Mouse
catabolic processGO:00090563180.014
molting cycle collagen and cuticulin based cuticleGO:00189962810.014
regulation of cellular component sizeGO:0032535400.014
cell projection assemblyGO:0030031350.014
cell maturationGO:0048469260.014
single organism biosynthetic processGO:0044711910.013
response to topologically incorrect proteinGO:0035966820.013
secretionGO:00469031470.013
cellular amino acid metabolic processGO:0006520150.013
innate immune responseGO:00450871900.013
Mouse Fly
intracellular transportGO:0046907770.013
organic hydroxy compound metabolic processGO:1901615250.013
aromatic compound catabolic processGO:00194391160.013
ras protein signal transductionGO:0007265310.013
regulation of cellular amine metabolic processGO:003323800.013
axonal fasciculationGO:0007413790.013
locomotory behaviorGO:0007626400.013
peptidyl tyrosine phosphorylationGO:001810820.013
regulation of synapse assemblyGO:005196320.013
cognitionGO:0050890270.012
pharyngeal pumpingGO:0043050580.012
amine metabolic processGO:0009308150.012
regulation of feeding behaviorGO:0060259380.012
regulation of protein import into nucleusGO:004230630.012
regulation of anatomical structure morphogenesisGO:0022603510.012
cellular macromolecular complex assemblyGO:00346221840.012
regulation of organelle organizationGO:00330431640.012
anion transportGO:0006820300.012
developmental maturationGO:0021700260.012
regulation of cellular component biogenesisGO:0044087260.012
negative regulation of rna biosynthetic processGO:1902679530.012
adult locomotory behaviorGO:000834410.012
neurotransmitter secretionGO:0007269260.012
regulation of cell migrationGO:0030334550.012
cellular amine metabolic processGO:0044106150.011
carboxylic acid metabolic processGO:0019752340.011
positive regulation of transportGO:0051050320.011
positive regulation of transferase activityGO:0051347210.011
regulation of cellular ketone metabolic processGO:001056530.011
ion transmembrane transportGO:0034220910.011
organic substance catabolic processGO:19015752940.011
canonical wnt signaling pathwayGO:006007030.011
actin cytoskeleton reorganizationGO:003153240.011
nucleobase containing small molecule metabolic processGO:00550861150.011
stress activated protein kinase signaling cascadeGO:0031098100.011
Mouse
regulation of neurotransmitter levelsGO:0001505360.011
regulation of canonical wnt signaling pathwayGO:006082810.011
learning or memoryGO:0007611270.011
negative regulation of response to stimulusGO:0048585730.011
response to other organismGO:00517071010.011
response to biotic stimulusGO:00096071010.011
regulation of kinase activityGO:0043549290.011
carboxylic acid transportGO:0046942150.011
protein localization to membraneGO:0072657110.011
regulation of cell developmentGO:0060284490.011
regulation of ion transportGO:0043269390.011
nucleobase containing compound catabolic processGO:00346551140.011
negative regulation of rna metabolic processGO:0051253530.010
synapse organizationGO:0050808240.010
Fly
response to bacteriumGO:0009617860.010
response to external biotic stimulusGO:00432071010.010
macromolecule catabolic processGO:00090572020.010
oocyte constructionGO:000730820.010
positive regulation of protein kinase activityGO:0045860180.010
regenerationGO:003109940.010
chromatin modificationGO:0016568320.010
regulation of anatomical structure sizeGO:0090066460.010
single organism intracellular transportGO:1902582700.010
regulation of cell sizeGO:0008361300.010
peptidyl tyrosine modificationGO:001821230.010

tol-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
disease of cellular proliferationDOID:1456600.015
nervous system diseaseDOID:86300.010
cancerDOID:16200.010
organ system cancerDOID:005068600.010