Caenorhabditis elegans

76 known processes

let-268 (CELE_F52H3.1)

Protein LET-268

let-268 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
extracellular structure organizationGO:004306270.512
Mouse
single organism reproductive processGO:004470211960.433
Worm
post embryonic developmentGO:000979121520.384
gonad developmentGO:00084068400.382
Worm
skeletal muscle organ developmentGO:006053830.358
cell motilityGO:00488703130.338
Zebrafish
vesicle mediated transportGO:00161928520.326
locomotionGO:004001116340.319
Zebrafish Worm
agingGO:00075688120.318
embryo developmentGO:000979030520.318
reproductive structure developmentGO:00486088500.313
Worm
developmental process involved in reproductionGO:000300611650.281
Worm
organ developmentGO:004851311020.278
Zebrafish Mouse Worm
embryo development ending in birth or egg hatchingGO:000979229920.272
axon developmentGO:00615641630.250
Zebrafish
reproductive system developmentGO:00614588500.242
Worm
cellular component movementGO:00069283880.241
Zebrafish
multicellular organism reproductionGO:00325048190.222
multicellular organismal agingGO:00102598120.209
development of primary sexual characteristicsGO:00451378400.208
Worm
determination of adult lifespanGO:00083408120.205
multicellular organismal reproductive processGO:00486098150.205
sex differentiationGO:00075489090.200
Worm
organelle organizationGO:00069967830.195
positive regulation of developmental growthGO:00486393540.194
receptor mediated endocytosisGO:00068987150.193
macromolecule localizationGO:00330367710.191
Mouse
hermaphrodite genitalia developmentGO:00400357340.189
Worm
sexual reproductionGO:00199535460.181
transportGO:000681010930.171
muscle tissue developmentGO:006053710.170
cellular component morphogenesisGO:00329893180.169
Zebrafish Mouse
muscle attachmentGO:001620330.168
nervous system developmentGO:00073992530.164
Zebrafish Mouse
regulation of multicellular organismal developmentGO:20000263170.163
cell migrationGO:00164773060.160
Zebrafish
response to chemicalGO:00422213560.151
Zebrafish
regulation of developmental processGO:00507936840.151
multi organism reproductive processGO:00447038670.151
genitalia developmentGO:00488067410.149
Worm
muscle organ morphogenesisGO:004864440.143
axonogenesisGO:00074091020.139
Zebrafish
anatomical structure formation involved in morphogenesisGO:00486462500.134
establishment of localizationGO:005123411710.129
regulation of multicellular organismal processGO:00512397260.128
muscle organ developmentGO:0007517260.123
neuron projection morphogenesisGO:00488121140.123
Zebrafish
muscle structure developmentGO:00610611910.122
single organism organelle organizationGO:19025895010.118
protein localizationGO:00081042050.118
Mouse
macromolecular complex subunit organizationGO:00439333200.117
Mouse
striated muscle cell differentiationGO:00511461580.117
cell developmentGO:00484686960.114
Zebrafish Mouse
multicellular organismal reproductive behaviorGO:00330573840.110
multicellular organism growthGO:00352643850.109
ovipositionGO:00189913640.107
positive regulation of growthGO:00459273690.103
cellular protein metabolic processGO:00442672790.102
generation of neuronsGO:00486992350.101
Zebrafish
cytoskeleton organizationGO:00070103390.100
chemotaxisGO:00069351200.100
Zebrafish
lipid localizationGO:00108765730.099
regulation of metabolic processGO:00192224780.099
regulation of multicellular organism growthGO:00400143730.098
endocytosisGO:00068978190.095
growthGO:00400075620.094
positive regulation of multicellular organism growthGO:00400183520.094
molting cycle collagen and cuticulin based cuticleGO:00189962810.092
extracellular matrix organizationGO:003019860.092
Mouse
system processGO:00030081360.090
Mouse
body morphogenesisGO:00101716200.090
germ cell developmentGO:00072813510.089
regulation of biological qualityGO:00650087410.085
Mouse
reproductive behaviorGO:00190983870.083
positive regulation of multicellular organismal processGO:00512404170.083
cell cycleGO:00070495260.083
basement membrane organizationGO:007171130.083
Mouse
negative regulation of biological processGO:00485195670.082
localization of cellGO:00516743130.081
Zebrafish
positive regulation of developmental processGO:00510944080.080
signalingGO:00230524010.080
post embryonic organ developmentGO:00485693360.078
maintenance of locationGO:00512355800.077
regulation of developmental growthGO:00486383890.077
muscle cell differentiationGO:00426921710.076
organonitrogen compound metabolic processGO:19015641510.076
multi multicellular organism processGO:00447063900.076
developmental growthGO:00485894120.076
catabolic processGO:00090563180.075
actin cytoskeleton organizationGO:00300361840.075
lipid storageGO:00199155650.074
regulation of vulval developmentGO:00400282480.073
multi organism reproductive behaviorGO:00447053870.072
gamete generationGO:00072764610.072
protein metabolic processGO:00195384220.071
neuron recognitionGO:0008038830.071
single organism transportGO:00447654470.071
cellular localizationGO:00516413600.068
organic substance catabolic processGO:19015752940.068
protein catabolic processGO:00301631620.067
regulation of nematode larval developmentGO:00610622600.066
nucleoside phosphate metabolic processGO:00067531080.066
oogenesisGO:00484772290.065
vulval developmentGO:00400253330.064
neuron projection guidanceGO:0097485820.064
Zebrafish
multi organism behaviorGO:00517053890.063
cell cycle processGO:00224024820.063
regulation of growthGO:00400084090.063
cellular process involved in reproduction in multicellular organismGO:00224123510.062
negative regulation of cellular processGO:00485232390.062
behaviorGO:00076105270.061
cell morphogenesisGO:00009021630.061
Zebrafish Mouse
neuron differentiationGO:00301822170.060
Zebrafish
negative regulation of vulval developmentGO:00400272060.059
regulation of macromolecule metabolic processGO:00602554210.059
female gamete generationGO:00072922540.059
single organism signalingGO:00447004010.058
positive regulation of locomotionGO:0040017420.058
positive regulation of cellular processGO:00485223320.058
organelle assemblyGO:00709252140.057
neuron projection developmentGO:00311751870.057
Zebrafish
cellular component biogenesisGO:00440852970.057
Mouse
neurogenesisGO:00220082360.057
Zebrafish
cell deathGO:00082195470.055
cell projection organizationGO:00300302310.055
Zebrafish
ribonucleoside triphosphate metabolic processGO:0009199870.053
myofibril assemblyGO:00302391540.053
cuticle developmentGO:00423351000.053
neuron developmentGO:00486661990.053
Zebrafish
signal transductionGO:00071653170.051
protein complex biogenesisGO:00702711860.050
cell projection morphogenesisGO:00488581480.050
Zebrafish
negative regulation of multicellular organismal processGO:00512412360.050
actomyosin structure organizationGO:00310321540.050
negative regulation of metabolic processGO:00098922400.049
regulation of cellular metabolic processGO:00313233050.049
cellular component assembly involved in morphogenesisGO:00109271830.049
macromolecule biosynthetic processGO:00090592500.049
meiotic cell cycleGO:00513213350.049
regulation of post embryonic developmentGO:00485802600.048
biosynthetic processGO:00090583230.048
carbohydrate derivative metabolic processGO:19011351410.047
cell surface receptor signaling pathwayGO:00071661490.047
single organism localizationGO:19025785180.047
macromolecule catabolic processGO:00090572020.045
response to external stimulusGO:00096052890.045
Zebrafish
cell substrate adhesionGO:003158910.045
striated muscle cell developmentGO:00550021570.044
actin filament based processGO:00300291910.043
secretionGO:00469031470.043
embryonic body morphogenesisGO:0010172490.042
cellular protein modification processGO:00064642070.042
deathGO:00162655470.042
regulation of nitrogen compound metabolic processGO:00511712220.042
negative regulation of nematode larval developmentGO:00610642080.040
protein complex subunit organizationGO:00718222800.040
Mouse
signal transduction by phosphorylationGO:0023014310.039
negative regulation of macromolecule metabolic processGO:00106052290.038
cell recognitionGO:0008037850.038
tissue developmentGO:00098881120.038
Zebrafish Mouse
striated muscle myosin thick filament assemblyGO:00716881380.038
small molecule metabolic processGO:00442811860.037
positive regulation of cell migrationGO:003033530.036
embryonic morphogenesisGO:00485981520.036
taxisGO:00423301280.035
Zebrafish
myosin filament assemblyGO:00310341380.035
negative regulation of cellular metabolic processGO:0031324950.035
regulation of catalytic activityGO:0050790780.034
inductive cell migrationGO:00400391450.034
regulation of primary metabolic processGO:00800902920.033
positive regulation of molecular functionGO:0044093610.033
response to organic substanceGO:00100331310.032
axon guidanceGO:0007411820.032
Zebrafish
cellular component assemblyGO:00226072930.031
Mouse
regulation of localizationGO:00328791940.031
negative regulation of post embryonic developmentGO:00485812080.031
apoptotic processGO:00069154780.031
cell part morphogenesisGO:00329901520.031
Zebrafish
macromolecule modificationGO:00434122180.030
muscle cell developmentGO:00550011580.030
organ morphogenesisGO:0009887670.030
Mouse
cellular protein complex assemblyGO:00436231780.030
programmed cell deathGO:00125015000.030
nucleobase containing compound metabolic processGO:00061394060.030
cell morphogenesis involved in neuron differentiationGO:00486671110.030
Zebrafish
negative regulation of developmental processGO:00510932270.030
meiotic nuclear divisionGO:00071263000.029
cellular macromolecular complex assemblyGO:00346221840.029
purine containing compound metabolic processGO:0072521950.029
regulation of cell migrationGO:0030334550.029
nucleobase containing compound biosynthetic processGO:00346541840.029
response to woundingGO:000961140.029
cellular biosynthetic processGO:00442493150.028
cell morphogenesis involved in differentiationGO:00009041120.028
Zebrafish Mouse
organic substance biosynthetic processGO:19015763230.028
regulation of locomotionGO:00400121610.028
rna metabolic processGO:00160702280.027
organelle fissionGO:00482853630.027
positive regulation of hydrolase activityGO:0051345380.027
macromolecular complex assemblyGO:00650031930.027
collagen and cuticulin based cuticle developmentGO:0040002990.027
regulation of cell communicationGO:00106461760.026
purine ribonucleoside catabolic processGO:0046130750.025
aromatic compound catabolic processGO:00194391160.025
response to abiotic stimulusGO:00096281520.025
Human
regulation of nucleobase containing compound metabolic processGO:00192192220.025
nucleoside metabolic processGO:0009116990.024
cellular response to chemical stimulusGO:00708871290.024
meiotic cell cycle processGO:19030461700.023
endodermal cell differentiationGO:0035987180.023
cellular nitrogen compound biosynthetic processGO:00442711920.023
head developmentGO:006032210.023
negative regulation of gene expressionGO:00106292170.023
epithelial tube morphogenesisGO:006056210.022
membrane organizationGO:00610241350.022
cell matrix adhesionGO:000716010.022
regulation of molecular functionGO:0065009890.022
cell divisionGO:00513012620.022
positive regulation of phosphate metabolic processGO:0045937560.021
regulation of biosynthetic processGO:00098891890.021
cellular macromolecule biosynthetic processGO:00346452470.021
tube developmentGO:00352951260.021
Mouse
myosin filament organizationGO:00310331380.021
regulation of organelle organizationGO:00330431640.021
regulation of cellular biosynthetic processGO:00313261890.021
ribonucleoside triphosphate catabolic processGO:0009203720.020
gene expressionGO:00104674120.020
oxoacid metabolic processGO:0043436470.020
regulation of response to stimulusGO:00485832430.020
regulation of reproductive processGO:2000241660.019
protein complex assemblyGO:00064611860.019
nucleotide catabolic processGO:0009166770.019
purine nucleotide catabolic processGO:0006195750.019
organic cyclic compound catabolic processGO:19013611190.019
digestive tract developmentGO:00485651220.019
chromosome segregationGO:00070591800.019
regulation of organ morphogenesisGO:200002740.019
muscle system processGO:0003012430.019
positive regulation of purine nucleotide catabolic processGO:0033123280.019
intracellular signal transductionGO:0035556960.019
purine nucleoside triphosphate metabolic processGO:0009144870.019
posttranscriptional regulation of gene expressionGO:00106081660.019
cytokinesisGO:0000910800.019
regulation of rna biosynthetic processGO:20011411650.019
regulation of transcription dna templatedGO:00063551640.019
enzyme linked receptor protein signaling pathwayGO:0007167500.018
regulation of nucleoside metabolic processGO:0009118370.018
nucleobase containing small molecule metabolic processGO:00550861150.018
organic substance transportGO:00717021130.018
tissue morphogenesisGO:0048729650.018
Mouse
axonal defasciculationGO:000741410.018
regulation of purine nucleotide metabolic processGO:1900542370.018
regulation of gene expressionGO:00104683660.017
positive regulation of catalytic activityGO:0043085590.017
heterocycle biosynthetic processGO:00181301870.017
regulation of cell motilityGO:2000145570.017
integrin mediated signaling pathwayGO:000722910.017
striated muscle contraction involved in embryonic body morphogenesisGO:0061199130.017
apoptotic cell clearanceGO:00432771110.017
cilium assemblyGO:0042384280.017
single organism biosynthetic processGO:0044711910.017
nucleic acid templated transcriptionGO:00976591690.016
digestive system developmentGO:00551231220.016
negative regulation of nitrogen compound metabolic processGO:0051172630.016
phagocytosisGO:00069091150.016
ribonucleoside metabolic processGO:0009119980.016
purine ribonucleotide metabolic processGO:0009150950.016
regulation of anatomical structure sizeGO:0090066460.016
Mouse
establishment of protein localization to membraneGO:009015030.016
cellular amino acid metabolic processGO:0006520150.016
cell type specific apoptotic processGO:009728540.015
regulation of protein metabolic processGO:0051246810.015
purine ribonucleoside metabolic processGO:0046128920.015
engulfment of apoptotic cellGO:0043652940.015
regulation of nucleotide metabolic processGO:0006140370.015
regulation of cellular component movementGO:0051270620.015
regulation of macromolecule biosynthetic processGO:00105561890.015
rna interferenceGO:00162461370.015
transcription from rna polymerase ii promoterGO:00063661490.015
peptidyl proline hydroxylation to 4 hydroxy l prolineGO:001840130.015
purine ribonucleoside triphosphate metabolic processGO:0009205870.015
regulation of cellular component organizationGO:00511282480.015
nucleic acid metabolic processGO:00903042990.014
eating behaviorGO:0042755590.014
glycosyl compound catabolic processGO:1901658790.014
somatic muscle developmentGO:000752510.014
axonal fasciculationGO:0007413790.014
response to oxygen levelsGO:0070482220.014
Human
nucleotide metabolic processGO:00091171080.013
pharyngeal pumpingGO:0043050580.013
regulation of purine nucleotide catabolic processGO:0033121350.013
pharynx developmentGO:0060465510.013
regulation of apoptotic signaling pathwayGO:200123310.013
innate immune responseGO:00450871900.013
phosphate containing compound metabolic processGO:00067962320.013
purine nucleotide metabolic processGO:0006163950.013
ribonucleotide catabolic processGO:0009261750.013
positive regulation of metabolic processGO:00098931870.013
axon extensionGO:0048675370.013
establishment of nucleus localizationGO:0040023550.013
cellular response to organic substanceGO:00713101190.013
purine nucleoside metabolic processGO:0042278920.013
organic cyclic compound biosynthetic processGO:19013621950.013
regulation of multi organism processGO:0043900690.013
regulation of cellular macromolecule biosynthetic processGO:20001121880.012
negative regulation of nucleobase containing compound metabolic processGO:0045934630.012
regulation of catabolic processGO:0009894570.012
regulation of behaviorGO:0050795970.012
ribose phosphate metabolic processGO:0019693990.012
epithelial cell proliferationGO:005067310.012
cellular nitrogen compound catabolic processGO:00442701190.012
nematode male tail tip morphogenesisGO:0045138770.012
regulation of epithelial cell proliferationGO:005067810.012
organic acid metabolic processGO:0006082470.012
cellular response to stressGO:00335541620.012
regulation of muscle cell differentiationGO:005114710.012
calcium mediated signalingGO:001972230.012
response to growth factorGO:0070848180.012
heterocycle catabolic processGO:00467001190.012
regulation of hydrolase activityGO:0051336450.012
posttranscriptional gene silencingGO:00164411430.012
positive regulation of nucleotide metabolic processGO:0045981280.012
regulation of gene expression epigeneticGO:00400291630.011
specification of axis polarityGO:0065001130.011
neurological system processGO:0050877530.011
positive regulation of nucleotide catabolic processGO:0030813280.011
chromosome organizationGO:00512761040.011
negative regulation of biosynthetic processGO:0009890650.011
positive regulation of nucleoside metabolic processGO:0045979280.011
ribonucleoside catabolic processGO:0042454770.011
nucleoside phosphate catabolic processGO:1901292770.011
protein modification processGO:00362112070.011
single organism cellular localizationGO:1902580720.011
glycosyl compound metabolic processGO:19016571000.011
excretionGO:0007588490.011
immune responseGO:00069551920.011
regulation of nucleotide catabolic processGO:0030811350.011
response to endogenous stimulusGO:0009719330.010
dopamine metabolic processGO:004241740.010
regulation of nucleic acid templated transcriptionGO:19035061650.010
purine nucleoside catabolic processGO:0006152750.010
response to oxygen containing compoundGO:1901700440.010
carbohydrate derivative catabolic processGO:1901136820.010
cellular response to transforming growth factor beta stimulusGO:0071560130.010
backward locomotionGO:0043057110.010
cell adhesionGO:0007155210.010
purine nucleoside triphosphate catabolic processGO:0009146720.010
memoryGO:000761330.010
regulation of signalingGO:00230511720.010
protein hydroxylationGO:001812650.010
sensory organ morphogenesisGO:009059620.010
regulation of cell cycleGO:00517261940.010

let-268 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.067
muscle tissue diseaseDOID:6600.042
cardiovascular system diseaseDOID:128700.042
cardiomyopathyDOID:005070000.042
heart diseaseDOID:11400.042
muscular diseaseDOID:008000000.042
myopathyDOID:42300.042
musculoskeletal system diseaseDOID:1700.042
intrinsic cardiomyopathyDOID:006003600.012
dilated cardiomyopathyDOID:1293000.012