Caenorhabditis elegans

80 known processes

dpl-1 (CELE_T23G7.1)

Protein DPL-1

dpl-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.899
embryo development ending in birth or egg hatchingGO:000979229920.750
meiotic cell cycleGO:00513213350.715
meiotic cell cycle processGO:19030461700.581
meiotic nuclear divisionGO:00071263000.533
sex differentiationGO:00075489090.530
regulation of developmental processGO:00507936840.515
developmental process involved in reproductionGO:000300611650.470
positive regulation of cellular processGO:00485223320.443
Mouse
positive regulation of nitrogen compound metabolic processGO:00511731340.426
Mouse
negative regulation of biological processGO:00485195670.413
regulation of cell cycle processGO:00105641450.402
cellular component movementGO:00069283880.371
organ developmentGO:004851311020.367
chromosome segregationGO:00070591800.363
axon developmentGO:00615641630.353
gonad developmentGO:00084068400.351
positive regulation of multicellular organismal processGO:00512404170.313
regulation of cell divisionGO:00513021420.293
regulation of multicellular organismal processGO:00512397260.292
establishment of organelle localizationGO:00516561230.278
meiotic chromosome segregationGO:00451321390.277
multicellular organismal reproductive processGO:00486098150.276
chromosome organizationGO:00512761040.268
cell divisionGO:00513012620.267
single organism reproductive processGO:004470211960.254
organelle fissionGO:00482853630.249
hermaphrodite genitalia developmentGO:00400357340.249
establishment of localizationGO:005123411710.246
cell cycle processGO:00224024820.232
nucleic acid metabolic processGO:00903042990.231
Mouse
apoptotic processGO:00069154780.224
Mouse
regulation of cell cycleGO:00517261940.219
genitalia developmentGO:00488067410.218
positive regulation of nucleobase containing compound metabolic processGO:00459351340.213
Mouse
multicellular organism reproductionGO:00325048190.212
development of primary sexual characteristicsGO:00451378400.204
mitotic spindle organizationGO:0007052810.198
sexual reproductionGO:00199535460.196
positive regulation of developmental processGO:00510944080.196
organelle organizationGO:00069967830.195
neuron projection developmentGO:00311751870.193
mitotic cell cycle processGO:19030471940.187
gamete generationGO:00072764610.182
cell deathGO:00082195470.181
multi organism reproductive processGO:00447038670.174
reproductive structure developmentGO:00486088500.173
mitotic sister chromatid segregationGO:0000070380.172
positive regulation of transcription dna templatedGO:00458931020.170
Mouse
programmed cell deathGO:00125015000.168
cell fate commitmentGO:00451651390.168
transportGO:000681010930.162
post embryonic developmentGO:000979121520.160
biosynthetic processGO:00090583230.155
Mouse
positive regulation of cellular metabolic processGO:00313251780.153
Mouse
negative regulation of cell cycleGO:0045786530.151
macromolecule biosynthetic processGO:00090592500.150
Mouse
organelle localizationGO:00516401270.149
growthGO:00400075620.143
locomotionGO:004001116340.143
pronuclear migrationGO:0035046510.142
developmental growthGO:00485894120.140
endocytosisGO:00068978190.136
cell cycleGO:00070495260.136
nucleobase containing compound metabolic processGO:00061394060.133
Mouse
reproductive system developmentGO:00614588500.130
regulation of macromolecule metabolic processGO:00602554210.127
Mouse
regulation of meiosisGO:0040020940.127
vulval developmentGO:00400253330.127
single organism transportGO:00447654470.127
tissue developmentGO:00098881120.123
Mouse
signalingGO:00230524010.120
response to chemicalGO:00422213560.120
positive regulation of metabolic processGO:00098931870.119
Mouse
regulation of biological qualityGO:00650087410.119
regulation of meiotic cell cycleGO:00514451360.119
protein metabolic processGO:00195384220.115
regulation of cellular component organizationGO:00511282480.110
transcription from rna polymerase ii promoterGO:00063661490.108
microtubule based processGO:00070171820.107
multicellular organism growthGO:00352643850.103
positive regulation of developmental growthGO:00486393540.103
cellular process involved in reproduction in multicellular organismGO:00224123510.101
single fertilizationGO:0007338610.100
regulation of mitotic cell cycleGO:0007346760.099
cellular biosynthetic processGO:00442493150.099
Mouse
chromatin modificationGO:0016568320.095
regulation of metabolic processGO:00192224780.095
Mouse
cell developmentGO:00484686960.094
cell motilityGO:00488703130.093
regulation of developmental growthGO:00486383890.093
regulation of multicellular organism growthGO:00400143730.091
regulation of multicellular organismal developmentGO:20000263170.091
positive regulation of growthGO:00459273690.091
cell projection organizationGO:00300302310.090
cellular protein modification processGO:00064642070.088
macromolecule modificationGO:00434122180.088
multicellular organismal agingGO:00102598120.087
regulation of rna biosynthetic processGO:20011411650.087
Mouse
negative regulation of macromolecule metabolic processGO:00106052290.086
agingGO:00075688120.083
sensory organ morphogenesisGO:009059620.081
tissue morphogenesisGO:0048729650.079
regulation of gene expressionGO:00104683660.079
Mouse
tube formationGO:003514820.078
canonical wnt signaling pathwayGO:006007030.077
deathGO:00162655470.077
macromolecule localizationGO:00330367710.076
body morphogenesisGO:00101716200.076
generation of neuronsGO:00486992350.074
vesicle mediated transportGO:00161928520.073
chromosome organization involved in meiosisGO:0070192250.072
positive regulation of rna metabolic processGO:00512541030.071
Mouse
transcription dna templatedGO:00063511680.071
Mouse
regulation of growthGO:00400084090.071
positive regulation of rna biosynthetic processGO:19026801020.070
Mouse
regulation of catabolic processGO:0009894570.070
ribonucleoprotein complex assemblyGO:002261840.070
fertilizationGO:0009566630.069
localization of cellGO:00516743130.068
germ cell developmentGO:00072813510.068
posttranscriptional gene silencingGO:00164411430.068
regulation of gene expression epigeneticGO:00400291630.068
post embryonic organ developmentGO:00485693360.067
single organism localizationGO:19025785180.067
establishment of localization in cellGO:00516493180.067
positive regulation of biosynthetic processGO:00098911090.067
Mouse
regulation of vulval developmentGO:00400282480.066
tube morphogenesisGO:0035239790.065
maintenance of locationGO:00512355800.065
determination of adult lifespanGO:00083408120.065
neuron developmentGO:00486661990.065
posttranscriptional gene silencing by rnaGO:00351941430.065
protein modification processGO:00362112070.065
regulation of nematode larval developmentGO:00610622600.065
cellular macromolecule biosynthetic processGO:00346452470.064
Mouse
lipid localizationGO:00108765730.062
cellular localizationGO:00516413600.061
regulation of transcription from rna polymerase ii promoterGO:00063571450.060
regulation of cell differentiationGO:0045595810.060
positive regulation of chromosome organizationGO:200125220.059
regulation of cellular metabolic processGO:00313233050.059
Mouse
digestive tract morphogenesisGO:0048546760.059
neuron projection morphogenesisGO:00488121140.058
negative regulation of macromolecule biosynthetic processGO:0010558650.058
rna metabolic processGO:00160702280.058
Mouse
lipid storageGO:00199155650.058
cell part morphogenesisGO:00329901520.058
gene silencingGO:00164581430.057
dna conformation changeGO:0071103110.057
response to organic substanceGO:00100331310.057
cell migrationGO:00164773060.057
neuron differentiationGO:00301822170.057
regulation of primary metabolic processGO:00800902920.056
Mouse
embryonic morphogenesisGO:00485981520.056
cellular response to stressGO:00335541620.055
sister chromatid segregationGO:0000819460.054
cytoskeleton organizationGO:00070103390.054
positive regulation of macromolecule metabolic processGO:00106041490.054
Mouse
multi multicellular organism processGO:00447063900.054
regulation of response to stimulusGO:00485832430.053
neurogenesisGO:00220082360.053
digestive tract developmentGO:00485651220.053
small molecule metabolic processGO:00442811860.053
positive regulation of multicellular organism growthGO:00400183520.053
negative regulation of post embryonic developmentGO:00485812080.052
positive regulation of nucleic acid templated transcriptionGO:19035081020.052
Mouse
ovipositionGO:00189913640.052
negative regulation of gene expressionGO:00106292170.051
cuticle developmentGO:00423351000.050
negative regulation of vulval developmentGO:00400272060.049
regulation of signalingGO:00230511720.048
axonogenesisGO:00074091020.047
negative regulation of nematode larval developmentGO:00610642080.047
receptor mediated endocytosisGO:00068987150.047
gene expressionGO:00104674120.046
Mouse
negative regulation of metabolic processGO:00098922400.046
regulation of chromosome organizationGO:0033044200.045
cellular protein metabolic processGO:00442672790.045
behaviorGO:00076105270.045
negative regulation of cellular processGO:00485232390.044
organic substance catabolic processGO:19015752940.044
positive regulation of cellular catabolic processGO:0031331350.043
collagen and cuticulin based cuticle developmentGO:0040002990.043
ubiquitin dependent protein catabolic processGO:0006511320.043
multicellular organismal reproductive behaviorGO:00330573840.043
spindle organizationGO:0007051920.042
catabolic processGO:00090563180.042
regulation of organelle organizationGO:00330431640.042
single organism organelle organizationGO:19025895010.041
nervous system developmentGO:00073992530.041
mitotic nuclear divisionGO:0007067890.041
response to external stimulusGO:00096052890.041
gene silencing by rnaGO:00310471430.040
single organism cellular localizationGO:1902580720.040
organic cyclic compound biosynthetic processGO:19013621950.039
Mouse
positive regulation of catalytic activityGO:0043085590.038
positive regulation of neurogenesisGO:005076940.038
regulation of cellular macromolecule biosynthetic processGO:20001121880.038
Mouse
modification dependent macromolecule catabolic processGO:0043632320.037
regulation of biosynthetic processGO:00098891890.037
Mouse
digestive system developmentGO:00551231220.037
muscle tissue developmentGO:006053710.036
head developmentGO:006032210.036
organonitrogen compound metabolic processGO:19015641510.035
negative regulation of developmental processGO:00510932270.035
posttranscriptional regulation of gene expressionGO:00106081660.034
histone modificationGO:0016570300.034
rna interferenceGO:00162461370.034
tube developmentGO:00352951260.034
cell morphogenesisGO:00009021630.034
regulation of nucleobase containing compound metabolic processGO:00192192220.034
Mouse
reproductive behaviorGO:00190983870.033
signal transductionGO:00071653170.033
positive regulation of gene expressionGO:00106281120.033
Mouse
macromolecular complex subunit organizationGO:00439333200.033
protein localizationGO:00081042050.033
regulation of post embryonic developmentGO:00485802600.032
regulation of cellular amine metabolic processGO:003323800.031
cellular component assemblyGO:00226072930.031
rna biosynthetic processGO:00327741690.031
Mouse
taxisGO:00423301280.030
protein phosphorylationGO:0006468850.030
response to abiotic stimulusGO:00096281520.030
anatomical structure formation involved in morphogenesisGO:00486462500.029
positive regulation of macromolecule biosynthetic processGO:00105571090.029
Mouse
regulation of transcription dna templatedGO:00063551640.029
Mouse
multi organism behaviorGO:00517053890.029
cellular catabolic processGO:00442481990.029
chromatin organizationGO:0006325320.029
nucleus localizationGO:0051647550.028
positive regulation of molecular functionGO:0044093610.028
chromatin assembly or disassemblyGO:000633310.028
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.028
negative regulation of multicellular organismal processGO:00512412360.027
positive regulation of cell cycleGO:0045787550.027
membrane organizationGO:00610241350.027
regulation of nuclear divisionGO:00517831150.027
regulation of phosphorus metabolic processGO:0051174810.027
regulation of intracellular signal transductionGO:1902531770.026
macromolecule catabolic processGO:00090572020.026
regulation of cellular biosynthetic processGO:00313261890.026
Mouse
chemotaxisGO:00069351200.026
epithelium developmentGO:0060429680.025
Mouse
regulation of signal transductionGO:00099661350.025
ras protein signal transductionGO:0007265310.025
meiosis iGO:0007127190.025
establishment of nucleus localizationGO:0040023550.025
covalent chromatin modificationGO:0016569300.025
nucleobase containing compound biosynthetic processGO:00346541840.024
Mouse
regulation of phosphorylationGO:0042325450.024
regulation of cellular ketone metabolic processGO:001056530.024
negative regulation of neurogenesisGO:005076840.023
organic acid metabolic processGO:0006082470.023
single organism catabolic processGO:00447121290.023
multi organism reproductive behaviorGO:00447053870.023
regenerationGO:003109940.022
phosphorylationGO:00163101160.022
regulation of phosphate metabolic processGO:0019220810.022
small gtpase mediated signal transductionGO:0007264320.022
regulation of rna metabolic processGO:00512521730.022
Mouse
positive regulation of gtpase activityGO:0043547280.022
negative regulation of nucleobase containing compound metabolic processGO:0045934630.022
cellular component biogenesisGO:00440852970.021
epithelial tube morphogenesisGO:006056210.021
muscle structure developmentGO:00610611910.021
regulation of cellular catabolic processGO:0031329510.021
endoderm developmentGO:0007492200.020
synapsisGO:0007129100.020
regulation of cell deathGO:0010941650.020
cell cycle phase transitionGO:0044770190.020
regulation of cell communicationGO:00106461760.020
heterocycle biosynthetic processGO:00181301870.020
Mouse
cellular nitrogen compound biosynthetic processGO:00442711920.020
Mouse
cellular macromolecule catabolic processGO:0044265730.020
regulation of localizationGO:00328791940.019
cellular protein localizationGO:0034613750.019
protein catabolic processGO:00301631620.019
negative regulation of cellular biosynthetic processGO:0031327650.019
regulation of apoptotic processGO:0042981360.019
chromosome separationGO:0051304190.019
negative regulation of mitotic cell cycleGO:0045930420.019
system processGO:00030081360.019
adult behaviorGO:003053430.018
regulation of nitrogen compound metabolic processGO:00511712220.018
Mouse
positive regulation of cell communicationGO:0010647690.018
regulation of programmed cell deathGO:0043067500.018
positive regulation of cellular biosynthetic processGO:00313281090.018
Mouse
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.018
dna metabolic processGO:0006259740.018
Mouse
positive regulation of mitotic sister chromatid separationGO:190197010.018
nucleobase containing small molecule metabolic processGO:00550861150.018
response to woundingGO:000961140.018
oxoacid metabolic processGO:0043436470.018
negative regulation of gene expression epigeneticGO:004581420.018
cytokinesisGO:0000910800.018
negative regulation of transcription dna templatedGO:0045892530.018
cell morphogenesis involved in neuron differentiationGO:00486671110.018
nucleic acid templated transcriptionGO:00976591690.017
Mouse
regulation of chromatin modificationGO:190330820.017
negative regulation of cellular component organizationGO:0051129330.017
oogenesisGO:00484772290.017
organic substance biosynthetic processGO:19015763230.017
Mouse
proteolysis involved in cellular protein catabolic processGO:0051603320.017
regulation of cell developmentGO:0060284490.017
aromatic compound biosynthetic processGO:00194381920.017
Mouse
chromatin assemblyGO:003149710.016
response to external biotic stimulusGO:00432071010.016
female gamete generationGO:00072922540.016
negative regulation of cell cycle processGO:0010948120.016
neuron projection guidanceGO:0097485820.016
regulation of cell cycle phase transitionGO:1901987130.016
response to other organismGO:00517071010.016
cellular response to dna damage stimulusGO:0006974410.015
nucleoside phosphate catabolic processGO:1901292770.015
dna geometric changeGO:003239230.015
synaptic growth at neuromuscular junctionGO:005112410.015
cell projection assemblyGO:0030031350.015
axon guidanceGO:0007411820.015
reciprocal meiotic recombinationGO:0007131110.015
positive regulation of phosphorus metabolic processGO:0010562560.015
gastrulationGO:0007369580.015
single organism signalingGO:00447004010.015
regulation of macromolecule biosynthetic processGO:00105561890.015
Mouse
long term memoryGO:000761620.015
proteolysisGO:0006508610.015
molting cycle collagen and cuticulin based cuticleGO:00189962810.014
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.014
cellular component morphogenesisGO:00329893180.014
nuclear migrationGO:0007097540.014
cell surface receptor signaling pathwayGO:00071661490.014
metaphase anaphase transition of mitotic cell cycleGO:0007091100.014
positive regulation of cellular protein catabolic processGO:190336430.014
ion transportGO:00068111130.014
phagocytosis engulfmentGO:0006911980.014
amine metabolic processGO:0009308150.014
regulation of epithelial cell proliferationGO:005067810.014
single organism behaviorGO:0044708830.014
mitotic cell cycle checkpointGO:000709350.014
carbohydrate derivative catabolic processGO:1901136820.014
positive regulation of catabolic processGO:0009896380.014
symbiosis encompassing mutualism through parasitismGO:004440350.014
positive regulation of hydrolase activityGO:0051345380.013
phosphorus metabolic processGO:00067932320.013
organ morphogenesisGO:0009887670.013
cell proliferationGO:00082831160.013
oocyte differentiationGO:0009994450.013
regulation of cytoplasmic transportGO:190364930.013
regulation of protein targetingGO:190353330.013
regulation of nucleic acid templated transcriptionGO:19035061650.013
Mouse
regulation of canonical wnt signaling pathwayGO:006082810.013
purine nucleoside metabolic processGO:0042278920.013
defense responseGO:00069522960.013
regulation of mitotic sister chromatid segregationGO:0033047160.013
negative regulation of nitrogen compound metabolic processGO:0051172630.012
carbohydrate derivative metabolic processGO:19011351410.012
response to biotic stimulusGO:00096071010.012
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361820.012
regulation of protein import into nucleusGO:004230630.012
cell cell signalingGO:00072671180.012
rna processingGO:0006396340.012
regulation of protein metabolic processGO:0051246810.012
protein localization to organelleGO:0033365370.012
modification dependent protein catabolic processGO:0019941320.012
chromatin remodelingGO:000633820.012
endodermal cell differentiationGO:0035987180.012
cytoskeleton dependent cytokinesisGO:0061640350.012
organophosphate metabolic processGO:00196371250.012
negative regulation of cellular metabolic processGO:0031324950.012
spindle checkpointGO:003157740.011
positive regulation of post embryonic developmentGO:0048582540.011
wnt signaling pathwayGO:0016055270.011
mitotic nuclear envelope reassemblyGO:000708430.011
heterocycle catabolic processGO:00467001190.011
positive regulation of vulval developmentGO:0040026520.011
cellular macromolecule localizationGO:0070727750.011
regulation of dna replicationGO:000627550.011
dna duplex unwindingGO:003250830.011
positive regulation of response to stimulusGO:0048584550.011
regulation of mitosisGO:0007088180.011
regulation of molecular functionGO:0065009890.011
cellular macromolecular complex assemblyGO:00346221840.011
regulation of stem cell differentiationGO:200073610.011
regulation of multi organism processGO:0043900690.011
protein modification by small protein conjugation or removalGO:0070647400.011
inductive cell migrationGO:00400391450.011
intracellular signal transductionGO:0035556960.011
reciprocal dna recombinationGO:0035825110.011
synapse organizationGO:0050808240.011
cellular amino acid metabolic processGO:0006520150.010
positive regulation of chromosome segregationGO:005198410.010
nucleobase containing compound catabolic processGO:00346551140.010
cell morphogenesis involved in differentiationGO:00009041120.010
protein complex subunit organizationGO:00718222800.010
regulation of histone modificationGO:003105610.010
purine ribonucleotide metabolic processGO:0009150950.010
internal peptidyl lysine acetylationGO:001839330.010
regulation of cellular amino acid metabolic processGO:000652100.010

dpl-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.027
disease of anatomical entityDOID:700.025
cancerDOID:16200.018
organ system cancerDOID:005068600.016
skin benign neoplasmDOID:316500.013
benign neoplasmDOID:006007200.013
hair follicle neoplasmDOID:537500.013
integumentary system benign neoplasmDOID:006012100.013
organ system benign neoplasmDOID:006008500.013