Caenorhabditis elegans

57 known processes

brc-1 (CELE_C36A4.8)

Protein BRC-1

brc-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.940
embryo development ending in birth or egg hatchingGO:000979229920.855
cell cycleGO:00070495260.793
organelle fissionGO:00482853630.680
chromosome segregationGO:00070591800.641
reproductive structure developmentGO:00486088500.634
meiotic chromosome segregationGO:00451321390.610
organ developmentGO:004851311020.594
meiotic cell cycle processGO:19030461700.588
single organism organelle organizationGO:19025895010.538
meiotic cell cycleGO:00513213350.504
reproductive system developmentGO:00614588500.502
regulation of gene expressionGO:00104683660.496
sex differentiationGO:00075489090.427
cell cycle processGO:00224024820.401
meiotic nuclear divisionGO:00071263000.400
negative regulation of biological processGO:00485195670.380
mitotic cell cycle processGO:19030471940.369
multicellular organismal reproductive processGO:00486098150.346
regulation of macromolecule metabolic processGO:00602554210.333
regulation of transcription dna templatedGO:00063551640.329
post embryonic developmentGO:000979121520.328
chromosome organizationGO:00512761040.324
cell divisionGO:00513012620.321
regulation of rna metabolic processGO:00512521730.318
cellular macromolecule biosynthetic processGO:00346452470.280
regulation of metabolic processGO:00192224780.273
macromolecule biosynthetic processGO:00090592500.271
nucleic acid metabolic processGO:00903042990.267
organelle organizationGO:00069967830.258
cellular biosynthetic processGO:00442493150.257
ovipositionGO:00189913640.248
negative regulation of metabolic processGO:00098922400.245
biosynthetic processGO:00090583230.244
response to chemicalGO:00422213560.240
gene expressionGO:00104674120.224
genitalia developmentGO:00488067410.220
aromatic compound biosynthetic processGO:00194381920.214
regulation of cellular macromolecule biosynthetic processGO:20001121880.208
gonad developmentGO:00084068400.199
regulation of cellular biosynthetic processGO:00313261890.197
negative regulation of cellular processGO:00485232390.194
nucleobase containing compound metabolic processGO:00061394060.190
hermaphrodite genitalia developmentGO:00400357340.180
pronuclear migrationGO:0035046510.176
nucleic acid templated transcriptionGO:00976591690.174
multicellular organism reproductionGO:00325048190.170
negative regulation of gene expressionGO:00106292170.160
multi multicellular organism processGO:00447063900.157
transcription dna templatedGO:00063511680.153
negative regulation of macromolecule metabolic processGO:00106052290.147
multi organism reproductive processGO:00447038670.145
dna metabolic processGO:0006259740.140
regulation of cell cycle processGO:00105641450.140
single organism reproductive processGO:004470211960.140
regulation of rna biosynthetic processGO:20011411650.140
cellular component movementGO:00069283880.138
regulation of primary metabolic processGO:00800902920.138
developmental process involved in reproductionGO:000300611650.132
organic substance biosynthetic processGO:19015763230.131
heterocycle biosynthetic processGO:00181301870.129
rna biosynthetic processGO:00327741690.127
regulation of biosynthetic processGO:00098891890.124
chromosome organization involved in meiosisGO:0070192250.124
rna metabolic processGO:00160702280.122
locomotionGO:004001116340.118
mitotic spindle organizationGO:0007052810.114
sister chromatid segregationGO:0000819460.112
cell developmentGO:00484686960.110
post embryonic organ developmentGO:00485693360.109
negative regulation of nematode larval developmentGO:00610642080.108
regulation of mitotic metaphase anaphase transitionGO:003007150.106
regulation of nitrogen compound metabolic processGO:00511712220.105
localization of cellGO:00516743130.099
regulation of multicellular organismal processGO:00512397260.098
multi organism reproductive behaviorGO:00447053870.097
vulval developmentGO:00400253330.097
macromolecule localizationGO:00330367710.096
organic cyclic compound biosynthetic processGO:19013621950.095
regulation of nucleic acid templated transcriptionGO:19035061650.091
regulation of transcription from rna polymerase ii promoterGO:00063571450.091
regulation of vulval developmentGO:00400282480.090
neurogenesisGO:00220082360.089
protein metabolic processGO:00195384220.087
deathGO:00162655470.087
macromolecule modificationGO:00434122180.087
regulation of biological qualityGO:00650087410.087
apoptotic processGO:00069154780.086
nucleobase containing compound biosynthetic processGO:00346541840.085
nucleus organizationGO:0006997380.085
regulation of nematode larval developmentGO:00610622600.085
regulation of cell divisionGO:00513021420.084
regulation of nucleobase containing compound metabolic processGO:00192192220.083
regulation of multicellular organism growthGO:00400143730.079
transportGO:000681010930.079
regulation of cell cycleGO:00517261940.078
cellular response to dna damage stimulusGO:0006974410.076
negative regulation of cellular biosynthetic processGO:0031327650.076
protein modification processGO:00362112070.076
cellular nitrogen compound biosynthetic processGO:00442711920.075
negative regulation of vulval developmentGO:00400272060.073
response to external stimulusGO:00096052890.073
cellular response to stressGO:00335541620.069
single fertilizationGO:0007338610.068
regulation of developmental processGO:00507936840.067
negative regulation of transcription dna templatedGO:0045892530.067
cellular protein metabolic processGO:00442672790.066
regulation of macromolecule biosynthetic processGO:00105561890.066
mitotic cell cycle checkpointGO:000709350.065
fertilizationGO:0009566630.065
epithelial tube morphogenesisGO:006056210.064
maintenance of locationGO:00512355800.064
cellular component morphogenesisGO:00329893180.064
negative regulation of chromosome segregationGO:005198540.063
establishment of localizationGO:005123411710.061
cell projection organizationGO:00300302310.060
anatomical structure formation involved in morphogenesisGO:00486462500.060
gene silencingGO:00164581430.059
multicellular organismal reproductive behaviorGO:00330573840.059
negative regulation of mitotic cell cycle phase transitionGO:190199150.058
nuclear migrationGO:0007097540.057
development of primary sexual characteristicsGO:00451378400.057
nervous system developmentGO:00073992530.057
generation of neuronsGO:00486992350.057
lipid storageGO:00199155650.056
transcription from rna polymerase ii promoterGO:00063661490.055
negative regulation of rna biosynthetic processGO:1902679530.055
gamete generationGO:00072764610.055
germ cell developmentGO:00072813510.054
behaviorGO:00076105270.054
cell part morphogenesisGO:00329901520.054
negative regulation of macromolecule biosynthetic processGO:0010558650.054
negative regulation of biosynthetic processGO:0009890650.054
negative regulation of nucleobase containing compound metabolic processGO:0045934630.053
negative regulation of mitotic cell cycleGO:0045930420.053
positive regulation of developmental processGO:00510944080.052
regulation of gene expression epigeneticGO:00400291630.052
tissue developmentGO:00098881120.052
mitotic nuclear divisionGO:0007067890.051
multi organism behaviorGO:00517053890.051
reproductive behaviorGO:00190983870.050
posttranscriptional gene silencingGO:00164411430.050
rna processingGO:0006396340.049
negative regulation of multicellular organismal processGO:00512412360.049
protein complex subunit organizationGO:00718222800.049
regulation of cellular metabolic processGO:00313233050.049
posttranscriptional regulation of gene expressionGO:00106081660.048
developmental growthGO:00485894120.047
positive regulation of cellular processGO:00485223320.047
cellular protein modification processGO:00064642070.047
negative regulation of developmental processGO:00510932270.047
macromolecular complex subunit organizationGO:00439333200.047
organonitrogen compound metabolic processGO:19015641510.046
negative regulation of post embryonic developmentGO:00485812080.046
positive regulation of multicellular organism growthGO:00400183520.046
microtubule based processGO:00070171820.045
positive regulation of developmental growthGO:00486393540.045
positive regulation of rna metabolic processGO:00512541030.045
regulation of developmental growthGO:00486383890.044
lipid localizationGO:00108765730.044
immune responseGO:00069551920.043
posttranscriptional gene silencing by rnaGO:00351941430.043
cell proliferationGO:00082831160.043
growthGO:00400075620.043
multicellular organismal agingGO:00102598120.041
cell motilityGO:00488703130.041
programmed cell deathGO:00125015000.040
cellular process involved in reproduction in multicellular organismGO:00224123510.040
agingGO:00075688120.039
positive regulation of multicellular organismal processGO:00512404170.039
protein complex assemblyGO:00064611860.038
multicellular organism growthGO:00352643850.038
cell migrationGO:00164773060.037
embryonic morphogenesisGO:00485981520.037
single organism biosynthetic processGO:0044711910.037
regulation of microtubule cytoskeleton organizationGO:0070507210.036
skeletal muscle organ developmentGO:006053830.036
muscle structure developmentGO:00610611910.036
regulation of multicellular organismal developmentGO:20000263170.036
sexual reproductionGO:00199535460.036
regulation of mitotic cell cycleGO:0007346760.036
gene silencing by rnaGO:00310471430.036
cell projection morphogenesisGO:00488581480.035
negative regulation of cell cycleGO:0045786530.035
regulation of growthGO:00400084090.035
positive regulation of growthGO:00459273690.035
cell fate commitmentGO:00451651390.035
regulation of post embryonic developmentGO:00485802600.034
regulation of dna replicationGO:000627550.033
regulation of cellular component organizationGO:00511282480.033
regulation of organelle organizationGO:00330431640.032
metaphase anaphase transition of mitotic cell cycleGO:0007091100.032
sensory organ morphogenesisGO:009059620.031
neuron projection developmentGO:00311751870.031
regenerationGO:003109940.031
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.030
body morphogenesisGO:00101716200.029
catabolic processGO:00090563180.029
chromatin modificationGO:0016568320.029
response to abiotic stimulusGO:00096281520.028
negative regulation of nitrogen compound metabolic processGO:0051172630.028
spindle organizationGO:0007051920.027
negative regulation of cellular metabolic processGO:0031324950.026
regulation of meiosisGO:0040020940.026
signal transductionGO:00071653170.026
signalingGO:00230524010.025
negative regulation of nucleic acid templated transcriptionGO:1903507530.025
epithelial cell proliferationGO:005067310.024
spindle assemblyGO:005122580.024
cell deathGO:00082195470.024
small molecule metabolic processGO:00442811860.024
mitotic sister chromatid separationGO:0051306130.024
cytoskeleton dependent cytokinesisGO:0061640350.024
phosphorus metabolic processGO:00067932320.024
positive regulation of chromosome organizationGO:200125220.024
polar body extrusion after meiotic divisionsGO:0040038140.023
organophosphate catabolic processGO:0046434810.023
cellular localizationGO:00516413600.023
neuron differentiationGO:00301822170.023
nucleus localizationGO:0051647550.023
protein complex biogenesisGO:00702711860.023
organic substance catabolic processGO:19015752940.022
mitotic g2 m transition checkpointGO:004481810.022
defense responseGO:00069522960.022
receptor mediated endocytosisGO:00068987150.022
tube morphogenesisGO:0035239790.022
regulation of cell proliferationGO:00421271050.021
neuron developmentGO:00486661990.021
cell morphogenesisGO:00009021630.021
dsrna fragmentationGO:0031050100.021
cell cycle phase transitionGO:0044770190.021
regulation of cell deathGO:0010941650.021
chromatin remodelingGO:000633820.021
organophosphate metabolic processGO:00196371250.020
negative regulation of cell cycle processGO:0010948120.020
mitotic sister chromatid segregationGO:0000070380.020
protein phosphorylationGO:0006468850.020
positive regulation of neurogenesisGO:005076940.020
phosphorylationGO:00163101160.019
carbohydrate derivative metabolic processGO:19011351410.019
single organism localizationGO:19025785180.019
male sex differentiationGO:0046661860.019
vesicle mediated transportGO:00161928520.019
spindle checkpointGO:003157740.019
regulation of cell cycle phase transitionGO:1901987130.019
cellular nitrogen compound catabolic processGO:00442701190.019
response to dsrnaGO:0043331100.019
response to organic substanceGO:00100331310.019
cell cycle dna replicationGO:004478630.018
cytoskeleton organizationGO:00070103390.018
negative regulation of mitotic metaphase anaphase transitionGO:004584140.017
ion transportGO:00068111130.017
synaptonemal complex assemblyGO:000713060.017
negative regulation of rna metabolic processGO:0051253530.017
regulation of multi organism processGO:0043900690.017
single organism signalingGO:00447004010.017
determination of adult lifespanGO:00083408120.016
response to nitrogen compoundGO:1901698250.016
meiosis iGO:0007127190.016
cellular catabolic processGO:00442481990.016
microtubule polymerization or depolymerizationGO:0031109220.016
cellular component biogenesisGO:00440852970.016
oogenesisGO:00484772290.016
aromatic compound catabolic processGO:00194391160.016
establishment of localization in cellGO:00516493180.015
cell morphogenesis involved in neuron differentiationGO:00486671110.015
male gamete generationGO:0048232410.015
cytokinesisGO:0000910800.015
negative regulation of neurogenesisGO:005076840.015
negative regulation of nuclear divisionGO:005178460.015
macromolecule catabolic processGO:00090572020.015
rna interferenceGO:00162461370.015
regulation of cellular protein metabolic processGO:0032268750.015
cell type specific apoptotic processGO:009728540.015
cellular response to organic substanceGO:00713101190.015
asymmetric cell divisionGO:0008356360.015
organelle localizationGO:00516401270.015
regulation of mitotic cell cycle phase transitionGO:190199070.015
single organism catabolic processGO:00447121290.014
microtubule cytoskeleton organization involved in mitosisGO:1902850120.014
positive regulation of chromosome segregationGO:005198410.014
inductive cell migrationGO:00400391450.014
regulation of cell differentiationGO:0045595810.014
negative regulation of mitosisGO:004583940.014
regulation of phosphate metabolic processGO:0019220810.014
cellular component assemblyGO:00226072930.014
dna packagingGO:000632370.014
regulation of phosphorylationGO:0042325450.013
tissue morphogenesisGO:0048729650.013
positive regulation of cell cycleGO:0045787550.013
regulation of kinase activityGO:0043549290.013
response to other organismGO:00517071010.013
dna recombinationGO:0006310190.013
metaphase anaphase transition of cell cycleGO:0044784150.013
defense response to other organismGO:00985421000.013
regulation of localizationGO:00328791940.013
positive regulation of macromolecule metabolic processGO:00106041490.013
taxisGO:00423301280.013
phosphate containing compound metabolic processGO:00067962320.013
cellular component assembly involved in morphogenesisGO:00109271830.013
dna conformation changeGO:0071103110.013
establishment of nucleus localizationGO:0040023550.013
regulation of epithelial cell proliferationGO:005067810.013
synaptonemal complex organizationGO:007019380.012
regulation of cytoplasmic transportGO:190364930.012
female gamete generationGO:00072922540.012
regulation of cell communicationGO:00106461760.012
nucleoside phosphate metabolic processGO:00067531080.012
regulation of epithelial cell differentiationGO:003085640.012
homeostatic processGO:0042592510.012
intracellular signal transductionGO:0035556960.012
regulation of programmed cell deathGO:0043067500.012
chromatin assembly or disassemblyGO:000633310.012
dna duplex unwindingGO:003250830.012
organic acid metabolic processGO:0006082470.012
regulation of phosphorus metabolic processGO:0051174810.011
cellular response to chemical stimulusGO:00708871290.011
cell surface receptor signaling pathwayGO:00071661490.011
protein oligomerizationGO:005125940.011
negative regulation of cell cycle phase transitionGO:190198860.011
regulation of chromosome organizationGO:0033044200.011
regulation of sister chromatid segregationGO:0033045160.011
cellular macromolecule catabolic processGO:0044265730.011
meiosis iiGO:0007135160.011
meiotic sister chromatid segregationGO:0045144150.011
neuron projection guidanceGO:0097485820.011
regulation of molecular functionGO:0065009890.011
chromatin organizationGO:0006325320.011
positive regulation of cell deathGO:0010942380.011
cellular response to nitrogen compoundGO:1901699240.011
establishment of organelle localizationGO:00516561230.011
regulation of meiotic cell cycleGO:00514451360.011
regulation of microtubule based processGO:0032886210.010
regulation of protein import into nucleusGO:004230630.010
digestive tract developmentGO:00485651220.010
regulation of transferase activityGO:0051338310.010
nematode male tail tip morphogenesisGO:0045138770.010
chromatin assemblyGO:003149710.010
negative regulation of mitotic sister chromatid segregationGO:003304840.010
organelle assemblyGO:00709252140.010
regulation of mitotic sister chromatid segregationGO:0033047160.010

brc-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.027
cancerDOID:16200.027
disease of cellular proliferationDOID:1456600.027
developmental disorder of mental healthDOID:006003700.011
disease of mental healthDOID:15000.011
gastrointestinal system cancerDOID:311900.011
disease of anatomical entityDOID:700.011