Caenorhabditis elegans

119 known processes

daf-18 (CELE_T07A9.6)

Protein DAF-18

daf-18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.791
Zebrafish
embryo development ending in birth or egg hatchingGO:000979229920.593
cell cycle processGO:00224024820.524
Human Mouse
organelle fissionGO:00482853630.353
Human Mouse
sex differentiationGO:00075489090.307
regulation of meiotic cell cycleGO:00514451360.288
endocytosisGO:00068978190.272
rna metabolic processGO:00160702280.264
Human
developmental process involved in reproductionGO:000300611650.247
Mouse
nucleobase containing compound metabolic processGO:00061394060.237
Human
post embryonic developmentGO:000979121520.234
regulation of macromolecule metabolic processGO:00602554210.233
Human Mouse
cell developmentGO:00484686960.233
Zebrafish Mouse Fly
organelle organizationGO:00069967830.209
Human Mouse Fly
protein metabolic processGO:00195384220.208
meiotic cell cycleGO:00513213350.207
reproductive system developmentGO:00614588500.204
Mouse
establishment of localizationGO:005123411710.198
regulation of developmental processGO:00507936840.182
Mouse Fly
organ developmentGO:004851311020.171
regulation of cellular component organizationGO:00511282480.168
Human Mouse Fly
cell divisionGO:00513012620.165
Human Mouse
nucleic acid metabolic processGO:00903042990.157
Human
sexual reproductionGO:00199535460.142
Mouse
macromolecule localizationGO:00330367710.139
meiotic nuclear divisionGO:00071263000.134
developmental growthGO:00485894120.134
Mouse Fly
regulation of multicellular organismal processGO:00512397260.131
Mouse Fly
gene expressionGO:00104674120.128
Human
cellular component biogenesisGO:00440852970.126
Human Mouse Fly
locomotionGO:004001116340.121
multicellular organism reproductionGO:00325048190.120
Mouse
single organism reproductive processGO:004470211960.118
Mouse
signalingGO:00230524010.116
Human Zebrafish Mouse Fly
development of primary sexual characteristicsGO:00451378400.116
apoptotic processGO:00069154780.114
Mouse Fly
regulation of vulval developmentGO:00400282480.111
cellular localizationGO:00516413600.110
regulation of metabolic processGO:00192224780.109
Human Mouse Fly
meiotic cell cycle processGO:19030461700.102
negative regulation of metabolic processGO:00098922400.101
Human
regulation of cell cycleGO:00517261940.099
Human Mouse Fly
gene silencingGO:00164581430.089
gamete generationGO:00072764610.085
regulation of multicellular organismal developmentGO:20000263170.084
Mouse Fly
negative regulation of gene expressionGO:00106292170.083
vesicle mediated transportGO:00161928520.083
lipid localizationGO:00108765730.083
Fly
maintenance of locationGO:00512355800.082
Fly
female gamete generationGO:00072922540.082
growthGO:00400075620.080
Mouse Fly
protein modification processGO:00362112070.079
regulation of cell divisionGO:00513021420.078
Human Mouse
lipid storageGO:00199155650.077
Fly
generation of neuronsGO:00486992350.077
Mouse Fly
single organism organelle organizationGO:19025895010.075
Human Mouse Fly
regulation of nematode larval developmentGO:00610622600.074
germ cell developmentGO:00072813510.073
reproductive structure developmentGO:00486088500.072
Mouse
hermaphrodite genitalia developmentGO:00400357340.072
cell deathGO:00082195470.071
Mouse Fly
multi organism reproductive processGO:00447038670.071
Mouse
multicellular organism growthGO:00352643850.070
Fly
neurogenesisGO:00220082360.068
Mouse Fly
regulation of gene expression epigeneticGO:00400291630.068
regulation of signalingGO:00230511720.067
Human Zebrafish Mouse
regulation of biological qualityGO:00650087410.066
Human Mouse Fly
regulation of post embryonic developmentGO:00485802600.066
cellular component assemblyGO:00226072930.066
Human Mouse Fly
programmed cell deathGO:00125015000.065
Mouse Fly
vulval developmentGO:00400253330.065
cellular process involved in reproduction in multicellular organismGO:00224123510.062
regulation of developmental growthGO:00486383890.061
Mouse Fly
agingGO:00075688120.061
determination of adult lifespanGO:00083408120.060
meiotic chromosome segregationGO:00451321390.059
gene silencing by rnaGO:00310471430.058
positive regulation of multicellular organismal processGO:00512404170.058
negative regulation of biological processGO:00485195670.058
protein localizationGO:00081042050.057
signal transductionGO:00071653170.055
Human Zebrafish Mouse Fly
behaviorGO:00076105270.054
oogenesisGO:00484772290.054
cell proliferationGO:00082831160.054
Human Mouse Fly
body morphogenesisGO:00101716200.052
deathGO:00162655470.052
Mouse Fly
macromolecule modificationGO:00434122180.052
regulation of cell proliferationGO:00421271050.052
Human Mouse Fly
receptor mediated endocytosisGO:00068987150.051
cell motilityGO:00488703130.051
Human Mouse
digestive tract morphogenesisGO:0048546760.050
Zebrafish
regulation of organelle organizationGO:00330431640.050
Human Mouse
transportGO:000681010930.049
positive regulation of growthGO:00459273690.047
posttranscriptional gene silencing by rnaGO:00351941430.047
positive regulation of developmental growthGO:00486393540.045
positive regulation of developmental processGO:00510944080.045
regulation of nitrogen compound metabolic processGO:00511712220.044
Human
regulation of multicellular organism growthGO:00400143730.043
Fly
single organism signalingGO:00447004010.042
Human Zebrafish Mouse Fly
microtubule based processGO:00070171820.041
cell cycleGO:00070495260.040
Human Mouse Fly
cellular component movementGO:00069283880.040
Human Mouse
nervous system developmentGO:00073992530.040
Mouse Fly
positive regulation of cell cycleGO:0045787550.039
Human Mouse
posttranscriptional gene silencingGO:00164411430.038
regulation of rna biosynthetic processGO:20011411650.038
Human
macromolecular complex assemblyGO:00650031930.038
regulation of meiosisGO:0040020940.038
cell migrationGO:00164773060.038
Human Mouse
establishment of localization in cellGO:00516493180.038
cellular protein metabolic processGO:00442672790.038
gonad developmentGO:00084068400.036
regulation of gene expressionGO:00104683660.036
Human
regulation of localizationGO:00328791940.036
post embryonic organ developmentGO:00485693360.035
negative regulation of cellular processGO:00485232390.035
cell cell signalingGO:00072671180.034
Mouse
cellular protein modification processGO:00064642070.034
single organism localizationGO:19025785180.033
regulation of growthGO:00400084090.033
Mouse Fly
regulation of cell cycle processGO:00105641450.033
Human Mouse
catabolic processGO:00090563180.033
Human Mouse Fly
regulation of nuclear divisionGO:00517831150.033
Human Mouse
rna interferenceGO:00162461370.033
negative regulation of macromolecule metabolic processGO:00106052290.032
Human
positive regulation of nucleobase containing compound metabolic processGO:00459351340.032
posttranscriptional regulation of gene expressionGO:00106081660.032
Human
negative regulation of developmental processGO:00510932270.032
Mouse Fly
establishment of organelle localizationGO:00516561230.031
transcription dna templatedGO:00063511680.031
Human
negative regulation of nematode larval developmentGO:00610642080.030
macromolecule biosynthetic processGO:00090592500.030
Human
negative regulation of multicellular organismal processGO:00512412360.029
Mouse Fly
cellular macromolecule biosynthetic processGO:00346452470.028
Human
asymmetric protein localizationGO:0008105350.028
protein complex subunit organizationGO:00718222800.028
Fly
positive regulation of multicellular organism growthGO:00400183520.027
heterocycle biosynthetic processGO:00181301870.027
Human
regulation of cellular macromolecule biosynthetic processGO:20001121880.026
Human
regulation of nucleobase containing compound metabolic processGO:00192192220.026
Human
positive regulation of metabolic processGO:00098931870.026
Human Mouse
secretion by cellGO:00329401380.026
inductive cell migrationGO:00400391450.025
cellular response to stressGO:00335541620.025
Fly
positive regulation of gene expressionGO:00106281120.025
response to chemicalGO:00422213560.024
molting cycle collagen and cuticulin based cuticleGO:00189962810.024
multicellular organismal reproductive processGO:00486098150.024
Mouse
multicellular organismal agingGO:00102598120.023
single organism transportGO:00447654470.023
regulation of protein localizationGO:0032880500.023
response to external stimulusGO:00096052890.023
protein complex biogenesisGO:00702711860.022
localization of cellGO:00516743130.022
Human Mouse
macromolecular complex subunit organizationGO:00439333200.022
Fly
cellular nitrogen compound biosynthetic processGO:00442711920.022
Human
reproductive behaviorGO:00190983870.021
Mouse
anatomical structure formation involved in morphogenesisGO:00486462500.020
Mouse
rna biosynthetic processGO:00327741690.020
Human
aromatic compound biosynthetic processGO:00194381920.020
Human
negative regulation of vulval developmentGO:00400272060.020
regulation of cell communicationGO:00106461760.020
Human Zebrafish Mouse
regulation of transcription dna templatedGO:00063551640.020
Human
macromolecule catabolic processGO:00090572020.020
Human Mouse
transcription from rna polymerase ii promoterGO:00063661490.019
regulation of biosynthetic processGO:00098891890.019
Human
defense responseGO:00069522960.019
Fly
regulation of ribosome biogenesisGO:009006910.019
Mouse
nucleic acid templated transcriptionGO:00976591690.019
Human
protein complex assemblyGO:00064611860.019
cell type specific apoptotic processGO:009728540.019
Mouse
positive regulation of proteasomal protein catabolic processGO:190180010.019
Human Mouse
positive regulation of cellular processGO:00485223320.019
Human Mouse
neuron differentiationGO:00301822170.018
Mouse Fly
regulation of primary metabolic processGO:00800902920.018
Human Mouse
axon developmentGO:00615641630.018
Mouse Fly
regulation of transcription from rna polymerase ii promoterGO:00063571450.018
system processGO:00030081360.018
organelle localizationGO:00516401270.018
Mouse
regulation of response to stimulusGO:00485832430.017
organic substance biosynthetic processGO:19015763230.017
Human
digestive tract developmentGO:00485651220.017
Zebrafish
regulation of epithelial cell proliferationGO:005067810.017
Mouse
response to woundingGO:000961140.017
Fly
chromosome organization involved in meiosisGO:0070192250.017
cellular macromolecular complex assemblyGO:00346221840.016
multicellular organismal reproductive behaviorGO:00330573840.016
Mouse
establishment of nucleus localizationGO:0040023550.016
canonical wnt signaling pathwayGO:006007030.016
Human
positive regulation of macromolecule biosynthetic processGO:00105571090.016
dna recombinationGO:0006310190.016
multi organism behaviorGO:00517053890.016
Mouse
cell substrate adhesionGO:003158910.015
Human
regulation of cellular ketone metabolic processGO:001056530.015
cell adhesionGO:0007155210.015
Human Fly
cellular protein complex assemblyGO:00436231780.015
biological adhesionGO:0022610210.015
Human Fly
protein catabolic processGO:00301631620.015
Human Mouse
cytoskeleton organizationGO:00070103390.015
Mouse Fly
cellular biosynthetic processGO:00442493150.014
Human
regulation of rna metabolic processGO:00512521730.014
Human
negative regulation of rna metabolic processGO:0051253530.014
rna localizationGO:000640330.014
response to organic substanceGO:00100331310.014
Fly
response to other organismGO:00517071010.014
sensory organ morphogenesisGO:009059620.014
Fly
negative regulation of nucleobase containing compound metabolic processGO:0045934630.014
biosynthetic processGO:00090583230.014
Human
secretionGO:00469031470.014
molting cycleGO:00423032810.014
cell surface receptor signaling pathwayGO:00071661490.013
Human Fly
positive regulation of meiotic cell cycleGO:0051446470.013
nuclear migrationGO:0007097540.013
positive regulation of cellular metabolic processGO:00313251780.013
Human Mouse
synapse organizationGO:0050808240.013
Mouse
negative regulation of transcription dna templatedGO:0045892530.013
nucleus localizationGO:0051647550.013
regulation of locomotionGO:00400121610.013
regulation of nucleic acid templated transcriptionGO:19035061650.013
Human
sex determinationGO:0007530600.012
positive regulation of neurogenesisGO:005076940.012
regulation of anatomical structure morphogenesisGO:0022603510.012
Mouse Fly
nucleobase containing compound biosynthetic processGO:00346541840.012
Human
regulation of molecular functionGO:0065009890.012
Human Mouse
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.012
epithelial tube morphogenesisGO:006056210.012
cellular response to organic substanceGO:00713101190.012
Fly
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.011
response to abiotic stimulusGO:00096281520.011
oocyte differentiationGO:0009994450.011
neuromuscular junction developmentGO:000752820.011
regulation of programmed cell deathGO:0043067500.011
Mouse
negative regulation of post embryonic developmentGO:00485812080.011
chromosome organizationGO:00512761040.011
Human Mouse
muscle structure developmentGO:00610611910.011
Fly
muscle cell differentiationGO:00426921710.011
developmental growth involved in morphogenesisGO:0060560370.011
positive regulation of epithelial cell proliferationGO:005067910.011
establishment or maintenance of cell polarityGO:0007163630.011
actin cytoskeleton organizationGO:00300361840.011
Fly
organic substance transportGO:00717021130.011
regulation of sequence specific dna binding transcription factor activityGO:005109030.011
Human
epithelial cell proliferationGO:005067310.010
Mouse
response to bacteriumGO:0009617860.010
dna metabolic processGO:0006259740.010
negative regulation of neurogenesisGO:005076840.010
Mouse Fly
organic substance catabolic processGO:19015752940.010
Human Mouse
organism emergence from protective structureGO:0071684480.010
cellular amine metabolic processGO:0044106150.010
negative regulation of cellular metabolic processGO:0031324950.010
Human
positive regulation of biosynthetic processGO:00098911090.010
establishment of spindle localizationGO:0051293510.010
muscle tissue developmentGO:006053710.010
Mouse
regulation of cell differentiationGO:0045595810.010
Mouse Fly
ovipositionGO:00189913640.010

daf-18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.023
Human
head and neck squamous cell carcinomaDOID:552000.023
Human
organ system cancerDOID:005068600.023
Human
head and neck carcinomaDOID:154200.023
Human
head and neck cancerDOID:1193400.023
Human
cancerDOID:16200.023
Human
thyroid cancerDOID:178100.021
Human
thyroid carcinomaDOID:396300.021
Human
endocrine gland cancerDOID:17000.021
Human
reproductive organ cancerDOID:19300.019
Human
endometrial carcinomaDOID:287100.019
Human
uterine cancerDOID:36300.019
Human
endometrial cancerDOID:138000.019
Human
female reproductive organ cancerDOID:12000.019
Human
male reproductive organ cancerDOID:385600.018
Human
prostate cancerDOID:1028300.018
Human
disease of anatomical entityDOID:700.015
epilepsy syndromeDOID:182600.012
variable age at onset electroclinical syndromeDOID:005070600.012
nervous system diseaseDOID:86300.012
central nervous system diseaseDOID:33100.012
electroclinical syndromeDOID:005070100.012
brain diseaseDOID:93600.012
benign neoplasmDOID:006007200.012
integumentary system benign neoplasmDOID:006012100.012
organ system benign neoplasmDOID:006008500.012
meningiomaDOID:356500.011
Human
familial meningiomaDOID:458600.011
Human
nervous system cancerDOID:309300.011
Human
central nervous system cancerDOID:362000.011
Human
heart diseaseDOID:11400.010
cardiovascular system diseaseDOID:128700.010
heart valve diseaseDOID:407900.010