Caenorhabditis elegans

0 known processes

wdr-5.3 (CELE_ZC302.2)

Protein WDR-5.3

wdr-5.3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.852
embryo development ending in birth or egg hatchingGO:000979229920.660
post embryonic developmentGO:000979121520.466
Worm
female gamete generationGO:00072922540.304
oogenesisGO:00484772290.303
regulation of vulval developmentGO:00400282480.240
Worm
multicellular organism reproductionGO:00325048190.234
protein metabolic processGO:00195384220.217
Human Mouse Worm Fly
germ cell developmentGO:00072813510.216
cell cycle processGO:00224024820.215
Fly
biosynthetic processGO:00090583230.214
Mouse
gonad developmentGO:00084068400.194
Worm
organ developmentGO:004851311020.188
Worm
cellular biosynthetic processGO:00442493150.179
Mouse
developmental process involved in reproductionGO:000300611650.171
Worm
dna duplex unwindingGO:003250830.161
cell deathGO:00082195470.152
Worm
reproductive structure developmentGO:00486088500.149
Worm
genitalia developmentGO:00488067410.142
protein complex subunit organizationGO:00718222800.135
chromosome segregationGO:00070591800.134
memoryGO:000761330.133
development of primary sexual characteristicsGO:00451378400.133
Worm
aromatic compound biosynthetic processGO:00194381920.128
Mouse
cellular nitrogen compound biosynthetic processGO:00442711920.126
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001121880.124
Mouse
gamete generationGO:00072764610.124
programmed cell deathGO:00125015000.114
Worm
sex differentiationGO:00075489090.114
Worm
sexual reproductionGO:00199535460.113
locomotionGO:004001116340.111
Worm
cellular process involved in reproduction in multicellular organismGO:00224123510.109
cellular localizationGO:00516413600.109
multicellular organismal reproductive processGO:00486098150.101
regulation of nematode larval developmentGO:00610622600.100
Worm
organelle organizationGO:00069967830.100
Human Mouse Worm Fly
chromosome organizationGO:00512761040.096
Human Mouse Worm Fly
regulation of developmental processGO:00507936840.095
Worm
cell cycleGO:00070495260.094
Fly
regulation of cell fate commitmentGO:0010453220.092
nucleobase containing compound biosynthetic processGO:00346541840.089
Mouse
deathGO:00162655470.088
Worm
single organism reproductive processGO:004470211960.087
Worm
regulation of multicellular organismal processGO:00512397260.086
Worm
regulation of post embryonic developmentGO:00485802600.085
Worm
body morphogenesisGO:00101716200.084
hermaphrodite genitalia developmentGO:00400357340.082
reproductive system developmentGO:00614588500.080
Worm
macromolecule biosynthetic processGO:00090592500.079
Mouse
cellular macromolecule biosynthetic processGO:00346452470.078
Mouse
phosphorus metabolic processGO:00067932320.076
oocyte developmentGO:0048599440.070
macromolecule localizationGO:00330367710.070
organic substance biosynthetic processGO:19015763230.068
Mouse
agingGO:00075688120.068
Worm
rna metabolic processGO:00160702280.065
Mouse
lipid storageGO:00199155650.064
positive regulation of multicellular organismal processGO:00512404170.064
mitotic cell cycle processGO:19030471940.061
Fly
regulation of biological qualityGO:00650087410.061
determination of adult lifespanGO:00083408120.060
Worm
posttranscriptional gene silencingGO:00164411430.060
maintenance of locationGO:00512355800.058
microtubule based processGO:00070171820.057
small molecule metabolic processGO:00442811860.057
Mouse
cellular component biogenesisGO:00440852970.056
long term memoryGO:000761620.056
behaviorGO:00076105270.056
gene silencingGO:00164581430.055
cellular protein modification processGO:00064642070.055
Human Mouse Worm Fly
lipid localizationGO:00108765730.055
heterocycle biosynthetic processGO:00181301870.054
Mouse
transcription dna templatedGO:00063511680.054
Mouse
negative regulation of vulval developmentGO:00400272060.053
Worm
vulval developmentGO:00400253330.051
Worm
tube formationGO:003514820.050
reproductive behaviorGO:00190983870.049
cellular protein metabolic processGO:00442672790.049
Human Mouse Worm Fly
regulation of cellular biosynthetic processGO:00313261890.049
Mouse
defense response to other organismGO:00985421000.048
developmental inductionGO:003112810.047
establishment of localization in cellGO:00516493180.047
negative regulation of gene expression epigeneticGO:004581420.046
posttranscriptional gene silencing by rnaGO:00351941430.046
regulation of gene expressionGO:00104683660.045
Mouse
cellular component assemblyGO:00226072930.045
gene silencing by rnaGO:00310471430.044
single organism organelle organizationGO:19025895010.044
Human Mouse Worm Fly
single organism behaviorGO:0044708830.043
ovipositionGO:00189913640.043
cellular component morphogenesisGO:00329893180.043
purine nucleoside monophosphate metabolic processGO:0009126430.043
regulation of nucleic acid templated transcriptionGO:19035061650.041
Mouse
cell developmentGO:00484686960.041
Rat
regulation of rna metabolic processGO:00512521730.040
Mouse
organic cyclic compound biosynthetic processGO:19013621950.039
Mouse
multi organism reproductive processGO:00447038670.039
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.039
nucleobase containing compound metabolic processGO:00061394060.039
Mouse
multi multicellular organism processGO:00447063900.039
rna biosynthetic processGO:00327741690.038
Mouse
positive regulation of growthGO:00459273690.038
single organism biosynthetic processGO:0044711910.038
Mouse
catabolic processGO:00090563180.038
regulation of gene expression epigeneticGO:00400291630.037
dna metabolic processGO:0006259740.037
positive regulation of cell morphogenesis involved in differentiationGO:001077040.037
regulation of protein metabolic processGO:0051246810.036
macromolecule modificationGO:00434122180.036
Human Mouse Worm Fly
regulation of cell fate specificationGO:0042659220.036
apoptotic processGO:00069154780.036
Worm
multicellular organism growthGO:00352643850.035
multi organism reproductive behaviorGO:00447053870.035
endocytosisGO:00068978190.034
rna interferenceGO:00162461370.034
anatomical structure formation involved in morphogenesisGO:00486462500.034
phosphate containing compound metabolic processGO:00067962320.034
cell fate commitmentGO:00451651390.034
regulation of transcription dna templatedGO:00063551640.033
Mouse
transportGO:000681010930.033
protein modification processGO:00362112070.033
Human Mouse Worm Fly
epithelial tube morphogenesisGO:006056210.032
gene expressionGO:00104674120.032
Mouse
head developmentGO:006032210.032
regulation of primary metabolic processGO:00800902920.032
Mouse
establishment of localizationGO:005123411710.032
single organism localizationGO:19025785180.032
macromolecular complex subunit organizationGO:00439333200.032
Human Mouse Worm Fly
multi organism behaviorGO:00517053890.032
multicellular organismal agingGO:00102598120.031
Worm
cellular protein complex assemblyGO:00436231780.031
regulation of cell cycle processGO:00105641450.031
Fly
pronuclear migrationGO:0035046510.031
response to abiotic stimulusGO:00096281520.031
oocyte differentiationGO:0009994450.030
vesicle mediated transportGO:00161928520.030
dendrite developmentGO:0016358420.029
regulation of rna biosynthetic processGO:20011411650.029
Mouse
organophosphate metabolic processGO:00196371250.029
sensory organ morphogenesisGO:009059620.029
protein localizationGO:00081042050.029
regulation of developmental growthGO:00486383890.028
ribonucleoside monophosphate metabolic processGO:0009161450.028
post embryonic organ developmentGO:00485693360.028
Worm
specification of axis polarityGO:0065001130.028
single organism signalingGO:00447004010.028
protein complex assemblyGO:00064611860.028
nucleobase containing compound catabolic processGO:00346551140.028
cell maturationGO:0048469260.028
positive regulation of neurogenesisGO:005076940.027
positive regulation of embryonic developmentGO:004001930.027
fertilizationGO:0009566630.027
meiotic cell cycleGO:00513213350.027
response to external stimulusGO:00096052890.027
regulation of nucleobase containing compound metabolic processGO:00192192220.027
Mouse
negative regulation of post embryonic developmentGO:00485812080.027
Worm
negative regulation of biosynthetic processGO:0009890650.027
negative regulation of cellular biosynthetic processGO:0031327650.026
regulation of organelle organizationGO:00330431640.026
response to organic substanceGO:00100331310.026
growthGO:00400075620.026
negative regulation of metabolic processGO:00098922400.025
carbohydrate derivative metabolic processGO:19011351410.025
negative regulation of biological processGO:00485195670.025
Worm Fly
positive regulation of developmental processGO:00510944080.025
nucleotide metabolic processGO:00091171080.025
cellular response to stressGO:00335541620.025
Fly
regulation of response to stimulusGO:00485832430.024
regulation of biosynthetic processGO:00098891890.024
Mouse
developmental growthGO:00485894120.024
regulation of macromolecule biosynthetic processGO:00105561890.024
Mouse
response to external biotic stimulusGO:00432071010.024
nucleic acid metabolic processGO:00903042990.024
Mouse
system processGO:00030081360.024
nucleoside phosphate metabolic processGO:00067531080.023
organonitrogen compound metabolic processGO:19015641510.023
response to oxygen containing compoundGO:1901700440.023
phagocytosis engulfmentGO:0006911980.023
multicellular organismal reproductive behaviorGO:00330573840.023
positive regulation of nucleobase containing compound metabolic processGO:00459351340.023
Mouse
cellular catabolic processGO:00442481990.022
phagocytosisGO:00069091150.022
canonical wnt signaling pathwayGO:006007030.022
purine ribonucleoside monophosphate metabolic processGO:0009167430.022
negative regulation of macromolecule metabolic processGO:00106052290.022
positive regulation of multicellular organism growthGO:00400183520.022
cytoskeleton organizationGO:00070103390.022
meiotic chromosome segregationGO:00451321390.022
positive regulation of developmental growthGO:00486393540.022
detection of external stimulusGO:000958140.022
macromolecule catabolic processGO:00090572020.022
cellular macromolecular complex assemblyGO:00346221840.022
meiotic cell cycle processGO:19030461700.022
nucleic acid templated transcriptionGO:00976591690.021
Mouse
cellular ketone metabolic processGO:0042180140.021
Mouse
nucleobase containing small molecule metabolic processGO:00550861150.021
cell part morphogenesisGO:00329901520.021
cellular nitrogen compound catabolic processGO:00442701190.020
single organism transportGO:00447654470.020
macromolecular complex assemblyGO:00650031930.020
regulation of metabolic processGO:00192224780.020
Mouse
regulation of multicellular organism growthGO:00400143730.020
proximal distal axis specificationGO:000994660.020
cell projection organizationGO:00300302310.020
Rat
apical junction assemblyGO:004329710.020
organelle fissionGO:00482853630.019
male sex differentiationGO:0046661860.019
regulation of growthGO:00400084090.019
regulation of multicellular organismal developmentGO:20000263170.019
Worm
homeostatic processGO:0042592510.019
meiotic nuclear divisionGO:00071263000.019
negative regulation of gene expressionGO:00106292170.019
neurological system processGO:0050877530.019
positive regulation of stem cell differentiationGO:200073810.018
striated muscle cell developmentGO:00550021570.018
neurogenesisGO:00220082360.018
Rat Fly
establishment of spindle orientationGO:0051294340.018
response to chemicalGO:00422213560.018
protein complex biogenesisGO:00702711860.018
positive regulation of protein metabolic processGO:0051247450.018
engulfment of apoptotic cellGO:0043652940.017
cell substrate adhesionGO:003158910.017
regulation of cellular protein metabolic processGO:0032268750.017
spindle organizationGO:0007051920.017
receptor mediated endocytosisGO:00068987150.017
response to other organismGO:00517071010.017
muscle tissue developmentGO:006053710.017
cell proliferationGO:00082831160.016
cell morphogenesis involved in differentiationGO:00009041120.016
embryonic morphogenesisGO:00485981520.016
organophosphate catabolic processGO:0046434810.016
regulation of mesoderm developmentGO:200038020.016
nuclear migrationGO:0007097540.016
regulation of cellular metabolic processGO:00313233050.016
Mouse
negative regulation of cell cycleGO:0045786530.015
Fly
chemotaxisGO:00069351200.015
positive regulation of bmp signaling pathwayGO:003051320.015
purine nucleoside metabolic processGO:0042278920.015
cell divisionGO:00513012620.015
regulation of behaviorGO:0050795970.015
protein oligomerizationGO:005125940.015
cell surface receptor signaling pathwayGO:00071661490.015
striated muscle myosin thick filament assemblyGO:00716881380.015
negative regulation of neurogenesisGO:005076840.015
rna localizationGO:000640330.015
notch signaling pathwayGO:0007219220.015
aromatic compound catabolic processGO:00194391160.015
posttranscriptional regulation of gene expressionGO:00106081660.015
regulation of multi organism processGO:0043900690.015
negative regulation of developmental processGO:00510932270.015
Worm
organ morphogenesisGO:0009887670.015
atp metabolic processGO:0046034420.014
purine containing compound metabolic processGO:0072521950.014
organonitrogen compound catabolic processGO:1901565900.014
regulation of organ morphogenesisGO:200002740.014
protein phosphorylationGO:0006468850.014
cellular response to endogenous stimulusGO:0071495320.014
negative regulation of nematode larval developmentGO:00610642080.014
Worm
cellular macromolecule catabolic processGO:0044265730.014
establishment of mitotic spindle orientationGO:0000132280.013
muscle structure developmentGO:00610611910.013
purine ribonucleoside metabolic processGO:0046128920.013
actin filament based processGO:00300291910.013
transcription from rna polymerase ii promoterGO:00063661490.013
Mouse
nucleoside monophosphate metabolic processGO:0009123460.013
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.013
response to biotic stimulusGO:00096071010.013
dna geometric changeGO:003239230.013
purine nucleoside monophosphate catabolic processGO:0009128280.013
negative regulation of nucleic acid templated transcriptionGO:1903507530.013
molting cycle collagen and cuticulin based cuticleGO:00189962810.013
sister chromatid segregationGO:0000819460.013
regulation of epithelial cell proliferationGO:005067810.013
apoptotic cell clearanceGO:00432771110.013
phosphorylationGO:00163101160.013
organelle assemblyGO:00709252140.013
detection of abiotic stimulusGO:000958240.013
positive regulation of macromolecule biosynthetic processGO:00105571090.013
Mouse
organic substance catabolic processGO:19015752940.013
cellular response to dna damage stimulusGO:0006974410.013
Fly
purine ribonucleoside monophosphate catabolic processGO:0009169280.013
negative regulation of macromolecule biosynthetic processGO:0010558650.013
single organism catabolic processGO:00447121290.013
purine ribonucleotide metabolic processGO:0009150950.013
inductive cell migrationGO:00400391450.012
cellular response to chemical stimulusGO:00708871290.012
regulation of sequence specific dna binding transcription factor activityGO:005109030.012
cell cell junction assemblyGO:000704320.012
cellular component assembly involved in morphogenesisGO:00109271830.012
regulation of localizationGO:00328791940.012
establishment of organelle localizationGO:00516561230.012
cell motilityGO:00488703130.012
Worm
epithelial cell proliferationGO:005067310.012
cellular response to inorganic substanceGO:007124130.012
skeletal muscle organ developmentGO:006053830.012
regulation of cell communicationGO:00106461760.012
developmental maturationGO:0021700260.011
myosin filament organizationGO:00310331380.011
organelle localizationGO:00516401270.011
regulation of cellular ketone metabolic processGO:001056530.011
Mouse
muscle cell developmentGO:00550011580.011
ion transportGO:00068111130.011
oxoacid metabolic processGO:0043436470.011
innate immune responseGO:00450871900.011
positive regulation of epithelial cell proliferationGO:005067910.011
chromatin organizationGO:0006325320.011
Human Mouse Worm Fly
positive regulation of rna metabolic processGO:00512541030.011
Mouse
mitotic nuclear divisionGO:0007067890.011
single fertilizationGO:0007338610.011
regulation of canonical wnt signaling pathwayGO:006082810.011
regulation of programmed cell deathGO:0043067500.011
regulation of signal transductionGO:00099661350.011
cellular response to oxygen containing compoundGO:1901701210.011
molting cycleGO:00423032810.011
cell migrationGO:00164773060.011
Worm
defense response to bacteriumGO:0042742860.010
muscle cell differentiationGO:00426921710.010
cell volume homeostasisGO:000688410.010
actin cytoskeleton organizationGO:00300361840.010
immune responseGO:00069551920.010
positive regulation of cell cycleGO:0045787550.010
defense responseGO:00069522960.010
ribonucleotide metabolic processGO:0009259990.010
cellular response to growth factor stimulusGO:0071363180.010
regulation of reproductive processGO:2000241660.010

wdr-5.3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
cardiovascular system diseaseDOID:128700.033
disease of cellular proliferationDOID:1456600.014
intestinal cancerDOID:1015500.013
gastrointestinal system cancerDOID:311900.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013
large intestine cancerDOID:567200.013