Caenorhabditis elegans

112 known processes

nmy-2 (CELE_F20G4.3)

Protein NMY-2

nmy-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic cell cycle processGO:19030471940.801
establishment of localizationGO:005123411710.794
microtubule based processGO:00070171820.697
Mouse
cytoskeleton organizationGO:00070103390.667
locomotionGO:004001116340.664
Human Mouse Worm Fly
embryo development ending in birth or egg hatchingGO:000979229920.621
transportGO:000681010930.595
reproductive structure developmentGO:00486088500.579
embryo developmentGO:000979030520.561
sex differentiationGO:00075489090.547
single organism organelle organizationGO:19025895010.486
cell cycleGO:00070495260.475
endocytosisGO:00068978190.456
cellular localizationGO:00516413600.454
Mouse Fly
gonad developmentGO:00084068400.407
multicellular organism reproductionGO:00325048190.400
Fly
hermaphrodite genitalia developmentGO:00400357340.391
receptor mediated endocytosisGO:00068987150.371
regulation of primary metabolic processGO:00800902920.352
vesicle mediated transportGO:00161928520.327
apoptotic processGO:00069154780.320
macromolecular complex subunit organizationGO:00439333200.314
single organism reproductive processGO:004470211960.291
purine nucleoside catabolic processGO:0006152750.291
Human Mouse
single organism localizationGO:19025785180.286
Mouse Fly
response to chemicalGO:00422213560.286
Mouse
organelle organizationGO:00069967830.260
single organism transportGO:00447654470.253
Mouse
development of primary sexual characteristicsGO:00451378400.252
regulation of metabolic processGO:00192224780.250
heterocycle catabolic processGO:00467001190.238
Human Mouse
sexual reproductionGO:00199535460.235
Fly
protein complex subunit organizationGO:00718222800.235
regulation of macromolecule metabolic processGO:00602554210.229
developmental process involved in reproductionGO:000300611650.228
mitotic spindle organizationGO:0007052810.208
cellular component biogenesisGO:00440852970.207
ribonucleoside catabolic processGO:0042454770.202
Human Mouse
post embryonic developmentGO:000979121520.200
head developmentGO:006032210.197
Mouse
regulation of growthGO:00400084090.195
cell cycle processGO:00224024820.195
multicellular organismal reproductive processGO:00486098150.193
Fly
phosphorus metabolic processGO:00067932320.181
Human Mouse
programmed cell deathGO:00125015000.179
gamete generationGO:00072764610.177
Fly
mitotic nuclear divisionGO:0007067890.172
germ cell developmentGO:00072813510.169
Fly
organic substance biosynthetic processGO:19015763230.167
multi organism reproductive processGO:00447038670.160
Fly
cellular process involved in reproduction in multicellular organismGO:00224123510.159
Fly
ras protein signal transductionGO:0007265310.158
macromolecule catabolic processGO:00090572020.155
spindle organizationGO:0007051920.153
Mouse
nucleobase containing compound metabolic processGO:00061394060.150
Human Mouse
regulation of developmental processGO:00507936840.150
protein localizationGO:00081042050.149
Human Worm Fly
protein catabolic processGO:00301631620.148
macromolecule biosynthetic processGO:00090592500.142
macromolecular complex assemblyGO:00650031930.139
multicellular organism growthGO:00352643850.138
positive regulation of cellular metabolic processGO:00313251780.138
phosphate containing compound metabolic processGO:00067962320.135
Human Mouse
macromolecule localizationGO:00330367710.132
Human Worm Fly
positive regulation of metabolic processGO:00098931870.130
cellular macromolecule biosynthetic processGO:00346452470.126
protein complex biogenesisGO:00702711860.126
regulation of cellular metabolic processGO:00313233050.125
protein metabolic processGO:00195384220.123
Human
cell morphogenesis involved in differentiationGO:00009041120.121
Human Mouse
cell deathGO:00082195470.119
organ developmentGO:004851311020.118
actin filament based processGO:00300291910.118
deathGO:00162655470.115
negative regulation of macromolecule metabolic processGO:00106052290.114
positive regulation of growthGO:00459273690.112
biosynthetic processGO:00090583230.112
ovipositionGO:00189913640.111
cell developmentGO:00484686960.110
cell divisionGO:00513012620.109
negative regulation of biological processGO:00485195670.108
purine ribonucleoside triphosphate catabolic processGO:0009207720.106
Human Mouse
cell fate commitmentGO:00451651390.106
cellular component movementGO:00069283880.105
Human Mouse Fly
nucleic acid metabolic processGO:00903042990.105
multicellular organismal agingGO:00102598120.105
multicellular organismal reproductive behaviorGO:00330573840.103
response to external stimulusGO:00096052890.102
Mouse
regulation of biosynthetic processGO:00098891890.102
regulation of protein metabolic processGO:0051246810.101
regulation of biological qualityGO:00650087410.099
reproductive system developmentGO:00614588500.098
actin cytoskeleton organizationGO:00300361840.098
negative regulation of metabolic processGO:00098922400.098
signal transductionGO:00071653170.096
regulation of gene expression epigeneticGO:00400291630.096
protein complex assemblyGO:00064611860.095
cellular biosynthetic processGO:00442493150.095
nucleotide catabolic processGO:0009166770.093
Human Mouse
cellular nitrogen compound catabolic processGO:00442701190.092
Human Mouse
positive regulation of cellular biosynthetic processGO:00313281090.092
nucleobase containing compound catabolic processGO:00346551140.092
Human Mouse
purine nucleotide catabolic processGO:0006195750.090
Human Mouse
single organism cellular localizationGO:1902580720.090
Mouse
microtubule cytoskeleton organization involved in mitosisGO:1902850120.089
organelle fissionGO:00482853630.086
ribose phosphate metabolic processGO:0019693990.085
Human Mouse
neuron projection morphogenesisGO:00488121140.084
Mouse
ribonucleoside triphosphate metabolic processGO:0009199870.084
Human Mouse
genitalia developmentGO:00488067410.083
organonitrogen compound catabolic processGO:1901565900.082
Human Mouse
neuron developmentGO:00486661990.082
lipid localizationGO:00108765730.082
nucleoside triphosphate catabolic processGO:0009143720.081
Human Mouse
dna metabolic processGO:0006259740.080
regulation of developmental growthGO:00486383890.079
multi organism behaviorGO:00517053890.079
multi multicellular organism processGO:00447063900.077
purine nucleoside triphosphate catabolic processGO:0009146720.076
Human Mouse
cellular component assemblyGO:00226072930.076
response to abiotic stimulusGO:00096281520.075
glycosyl compound catabolic processGO:1901658790.074
Human Mouse
ribonucleoside metabolic processGO:0009119980.073
Human Mouse
purine nucleotide metabolic processGO:0006163950.073
Human Mouse
meiotic nuclear divisionGO:00071263000.073
organophosphate catabolic processGO:0046434810.072
Human Mouse
regulation of cellular macromolecule biosynthetic processGO:20001121880.072
cellular component morphogenesisGO:00329893180.071
maintenance of locationGO:00512355800.071
Fly
regulation of signal transductionGO:00099661350.070
neuron projection developmentGO:00311751870.070
regulation of nucleobase containing compound metabolic processGO:00192192220.070
regulation of gene expressionGO:00104683660.069
rho protein signal transductionGO:000726620.069
cell morphogenesisGO:00009021630.069
chromosome organizationGO:00512761040.069
gene expressionGO:00104674120.068
growthGO:00400075620.068
generation of neuronsGO:00486992350.067
establishment of localization in cellGO:00516493180.066
Mouse
localization of cellGO:00516743130.065
Human Mouse Fly
single organism signalingGO:00447004010.065
catabolic processGO:00090563180.065
Human Mouse
positive regulation of phosphate metabolic processGO:0045937560.065
determination of adult lifespanGO:00083408120.065
neuron differentiationGO:00301822170.064
cell migrationGO:00164773060.064
Human Mouse Fly
neuron projection guidanceGO:0097485820.063
Mouse
cellular nitrogen compound biosynthetic processGO:00442711920.063
nervous system developmentGO:00073992530.062
lipid storageGO:00199155650.062
positive regulation of multicellular organism growthGO:00400183520.061
response to woundingGO:000961140.061
Human Mouse Fly
regulation of multicellular organism growthGO:00400143730.061
organic cyclic compound biosynthetic processGO:19013621950.061
axon developmentGO:00615641630.061
negative regulation of gene expressionGO:00106292170.061
small molecule metabolic processGO:00442811860.061
Human Mouse
agingGO:00075688120.061
cellular catabolic processGO:00442481990.060
Human Mouse
cell morphogenesis involved in neuron differentiationGO:00486671110.060
Mouse
positive regulation of developmental growthGO:00486393540.059
cell projection organizationGO:00300302310.057
macromolecule modificationGO:00434122180.057
single organism catabolic processGO:00447121290.055
Human Mouse
negative regulation of multicellular organismal processGO:00512412360.055
cellular protein modification processGO:00064642070.055
purine containing compound metabolic processGO:0072521950.053
Human Mouse
aromatic compound catabolic processGO:00194391160.053
Human Mouse
posttranscriptional regulation of gene expressionGO:00106081660.052
reproductive behaviorGO:00190983870.051
regulation of nitrogen compound metabolic processGO:00511712220.051
phosphorylationGO:00163101160.051
cellular response to stressGO:00335541620.051
female gamete generationGO:00072922540.051
Fly
membrane invaginationGO:0010324980.051
phagocytosisGO:00069091150.050
response to organic substanceGO:00100331310.050
multi organism reproductive behaviorGO:00447053870.050
chromosome organization involved in meiosisGO:0070192250.050
cell cycle phase transitionGO:0044770190.048
neurogenesisGO:00220082360.048
organophosphate metabolic processGO:00196371250.048
Human Mouse
positive regulation of macromolecule metabolic processGO:00106041490.048
organic substance catabolic processGO:19015752940.046
Human Mouse
organelle assemblyGO:00709252140.046
positive regulation of catabolic processGO:0009896380.046
phagocytosis engulfmentGO:0006911980.046
developmental growthGO:00485894120.046
negative regulation of cellular processGO:00485232390.045
rna metabolic processGO:00160702280.044
purine nucleoside metabolic processGO:0042278920.044
Human Mouse
positive regulation of multicellular organismal processGO:00512404170.044
synapsisGO:0007129100.044
negative regulation of cellular component organizationGO:0051129330.044
chromosome segregationGO:00070591800.044
purine nucleoside triphosphate metabolic processGO:0009144870.043
Human Mouse
cell projection morphogenesisGO:00488581480.043
Mouse
regulation of rna biosynthetic processGO:20011411650.043
signalingGO:00230524010.043
ribonucleoside triphosphate catabolic processGO:0009203720.043
Human Mouse
ribonucleotide catabolic processGO:0009261750.042
Human Mouse
meiotic cell cycle processGO:19030461700.042
Mouse
oocyte axis specificationGO:000730920.041
purine ribonucleotide metabolic processGO:0009150950.041
Human Mouse
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.041
positive regulation of catalytic activityGO:0043085590.040
positive regulation of nitrogen compound metabolic processGO:00511731340.040
positive regulation of macromolecule biosynthetic processGO:00105571090.040
purine ribonucleoside triphosphate metabolic processGO:0009205870.040
Human Mouse
establishment of organelle localizationGO:00516561230.039
Mouse
nucleoside catabolic processGO:0009164780.039
Human Mouse
purine ribonucleoside catabolic processGO:0046130750.039
Human Mouse
small gtpase mediated signal transductionGO:0007264320.039
cellular protein complex assemblyGO:00436231780.039
cellular response to dna damage stimulusGO:0006974410.039
vulval developmentGO:00400253330.039
carbohydrate derivative metabolic processGO:19011351410.039
Human Mouse
oocyte differentiationGO:0009994450.039
purine ribonucleotide catabolic processGO:0009154750.039
Human Mouse
maintenance of location in cellGO:0051651120.038
Fly
cellular macromolecule localizationGO:0070727750.038
Fly
behaviorGO:00076105270.038
oogenesisGO:00484772290.038
Fly
glycosyl compound metabolic processGO:19016571000.038
Human Mouse
negative regulation of developmental processGO:00510932270.037
oocyte constructionGO:000730820.037
single fertilizationGO:0007338610.037
regulation of cellular biosynthetic processGO:00313261890.037
regulation of macromolecule biosynthetic processGO:00105561890.037
regulation of phosphorus metabolic processGO:0051174810.037
nucleobase containing small molecule metabolic processGO:00550861150.036
Human Mouse
nucleobase containing compound biosynthetic processGO:00346541840.036
meiosis iGO:0007127190.036
regulation of ras protein signal transductionGO:0046578410.036
nucleoside phosphate catabolic processGO:1901292770.035
Human Mouse
protein modification processGO:00362112070.035
positive regulation of biosynthetic processGO:00098911090.035
nucleoside phosphate metabolic processGO:00067531080.035
Human Mouse
gene silencingGO:00164581430.035
positive regulation of gene expressionGO:00106281120.035
regulation of rna metabolic processGO:00512521730.034
regulation of mitotic cell cycleGO:0007346760.034
body morphogenesisGO:00101716200.034
Worm
cellular protein localizationGO:0034613750.033
Fly
nucleus organizationGO:0006997380.033
engulfment of apoptotic cellGO:0043652940.033
negative regulation of cellular metabolic processGO:0031324950.033
stem cell divisionGO:0017145180.033
dna conformation changeGO:0071103110.033
regulation of multicellular organismal processGO:00512397260.033
establishment of nucleus localizationGO:0040023550.033
Mouse
post embryonic organ developmentGO:00485693360.033
Fly
aromatic compound biosynthetic processGO:00194381920.033
axonogenesisGO:00074091020.032
Mouse
response to external biotic stimulusGO:00432071010.032
apoptotic cell clearanceGO:00432771110.032
regulation of cytoplasmic transportGO:190364930.032
posttranscriptional gene silencingGO:00164411430.032
nucleotide metabolic processGO:00091171080.032
Human Mouse
regulation of response to stimulusGO:00485832430.031
cell motilityGO:00488703130.031
Human Mouse Fly
carbohydrate derivative catabolic processGO:1901136820.030
Human Mouse
regulation of localizationGO:00328791940.030
cell part morphogenesisGO:00329901520.030
Mouse
positive regulation of molecular functionGO:0044093610.030
regulation of locomotionGO:00400121610.030
rna interferenceGO:00162461370.030
axon guidanceGO:0007411820.030
Mouse
protein phosphorylationGO:0006468850.030
cellular macromolecular complex assemblyGO:00346221840.030
regulation of phosphate metabolic processGO:0019220810.029
positive regulation of cellular processGO:00485223320.029
regulation of small gtpase mediated signal transductionGO:0051056410.029
regulation of nucleocytoplasmic transportGO:004682230.029
male gamete generationGO:0048232410.029
cuticle developmentGO:00423351000.028
Worm Fly
dna recombinationGO:0006310190.028
negative regulation of gene expression epigeneticGO:004581420.028
cellular macromolecule catabolic processGO:0044265730.028
atp metabolic processGO:0046034420.027
Human Mouse
rna localizationGO:000640330.027
sister chromatid segregationGO:0000819460.026
chromatin remodelingGO:000633820.026
negative regulation of nitrogen compound metabolic processGO:0051172630.026
muscle cell differentiationGO:00426921710.026
single organism intracellular transportGO:1902582700.025
regulation of cellular protein metabolic processGO:0032268750.025
regulation of cell divisionGO:00513021420.025
posttranscriptional gene silencing by rnaGO:00351941430.025
response to heatGO:0009408500.025
dna packagingGO:000632370.025
intracellular transportGO:0046907770.024
lipid metabolic processGO:0006629770.024
regulation of signalingGO:00230511720.024
ribonucleotide metabolic processGO:0009259990.024
Human Mouse
meiotic cell cycleGO:00513213350.024
Mouse
heterocycle biosynthetic processGO:00181301870.023
nucleoside triphosphate metabolic processGO:0009141870.023
Human Mouse
ribonucleoside monophosphate metabolic processGO:0009161450.023
Human Mouse
rna biosynthetic processGO:00327741690.023
negative regulation of nucleic acid templated transcriptionGO:1903507530.023
regulation of catalytic activityGO:0050790780.023
transcription from rna polymerase ii promoterGO:00063661490.023
positive regulation of response to stimulusGO:0048584550.023
nucleoside metabolic processGO:0009116990.023
Human Mouse
response to other organismGO:00517071010.023
positive regulation of nucleobase containing compound metabolic processGO:00459351340.023
cellular response to chemical stimulusGO:00708871290.022
regulation of intracellular signal transductionGO:1902531770.022
membrane organizationGO:00610241350.022
Mouse
embryonic morphogenesisGO:00485981520.022
Fly
atp catabolic processGO:0006200270.022
Human Mouse
oocyte developmentGO:0048599440.022
response to biotic stimulusGO:00096071010.022
positive regulation of phosphorus metabolic processGO:0010562560.022
transcription dna templatedGO:00063511680.022
positive regulation of developmental processGO:00510944080.022
regulation of cell communicationGO:00106461760.021
organic cyclic compound catabolic processGO:19013611190.021
Human Mouse
cellular response to organic substanceGO:00713101190.021
cellular response to abiotic stimulusGO:007121440.021
taxisGO:00423301280.021
Mouse
gene silencing by rnaGO:00310471430.021
regulation of cellular component organizationGO:00511282480.021
regulation of cell differentiationGO:0045595810.021
Zebrafish
actomyosin structure organizationGO:00310321540.020
regulation of meiotic cell cycleGO:00514451360.020
positive regulation of protein metabolic processGO:0051247450.020
negative regulation of nucleobase containing compound metabolic processGO:0045934630.020
regulation of catabolic processGO:0009894570.020
nucleus localizationGO:0051647550.019
Mouse
establishment or maintenance of cell polarityGO:0007163630.019
Mouse
tissue developmentGO:00098881120.019
Zebrafish Mouse Fly
maintenance of protein locationGO:0045185150.019
Fly
regulation of transcription dna templatedGO:00063551640.019
molting cycle collagen and cuticulin based cuticleGO:00189962810.019
intracellular signal transductionGO:0035556960.019
regulation of transcription from rna polymerase ii promoterGO:00063571450.019
positive regulation of cellular catabolic processGO:0031331350.018
mitotic g2 m transition checkpointGO:004481810.018
regulation of cellular catabolic processGO:0031329510.018
response to bacteriumGO:0009617860.018
purine containing compound catabolic processGO:0072523750.018
Human Mouse
cell cycle g2 m phase transitionGO:004483910.018
regulation of organelle organizationGO:00330431640.018
regulation of nucleic acid templated transcriptionGO:19035061650.018
epithelium developmentGO:0060429680.017
Zebrafish Fly
negative regulation of rna biosynthetic processGO:1902679530.017
tube developmentGO:00352951260.017
Zebrafish Fly
regulation of nuclear divisionGO:00517831150.017
innate immune responseGO:00450871900.016
regulation of protein targetingGO:190353330.016
response to oxygen containing compoundGO:1901700440.016
collagen and cuticulin based cuticle developmentGO:0040002990.015
Worm
cellular protein metabolic processGO:00442672790.015
positive regulation of phosphorylationGO:0042327270.015
nucleoside monophosphate metabolic processGO:0009123460.015
Human Mouse
regulation of cell cycle processGO:00105641450.015
nucleic acid templated transcriptionGO:00976591690.015
regulation of phosphorylationGO:0042325450.015
cellular amine metabolic processGO:0044106150.015
regulation of cellular component biogenesisGO:0044087260.015
anatomical structure formation involved in morphogenesisGO:00486462500.015
defense responseGO:00069522960.015
protein localization to nucleusGO:0034504110.015
regulation of cell developmentGO:0060284490.015
regulation of cellular amine metabolic processGO:003323800.015
protein localization to organelleGO:0033365370.015
actin filament based movementGO:003004840.015
Human Mouse
pattern specification processGO:0007389590.014
neuroblast divisionGO:005505790.014
purine ribonucleoside monophosphate metabolic processGO:0009167430.014
Human Mouse
organonitrogen compound metabolic processGO:19015641510.014
Human Mouse
regulation of protein import into nucleusGO:004230630.014
double strand break repairGO:000630250.014
purine nucleoside monophosphate metabolic processGO:0009126430.014
Human Mouse
somatic stem cell divisionGO:004810390.014
single organism biosynthetic processGO:0044711910.014
regulation of cell proliferationGO:00421271050.014
nuclear pore organizationGO:000699920.014
muscle structure developmentGO:00610611910.014
regulation of chromosome organizationGO:0033044200.014
positive regulation of rna metabolic processGO:00512541030.014
chromatin assembly or disassemblyGO:000633310.014
purine nucleoside monophosphate catabolic processGO:0009128280.013
Human Mouse
dna duplex unwindingGO:003250830.013
cellular component assembly involved in morphogenesisGO:00109271830.013
spindle assembly involved in mitosisGO:009030760.013
amine metabolic processGO:0009308150.013
establishment of rna localizationGO:005123630.013
positive regulation of hydrolase activityGO:0051345380.013
mitotic chromosome condensationGO:000707630.013
establishment of protein localizationGO:0045184500.013
Human
nematode male tail tip morphogenesisGO:0045138770.013
purine ribonucleoside monophosphate catabolic processGO:0009169280.013
Human Mouse
negative regulation of neurogenesisGO:005076840.013
negative regulation of rna metabolic processGO:0051253530.013
inductive cell migrationGO:00400391450.012
molting cycleGO:00423032810.012
regulation of cytoskeleton organizationGO:0051493410.012
digestive system developmentGO:00551231220.012
Zebrafish Fly
synaptonemal complex assemblyGO:000713060.012
regulation of molecular functionGO:0065009890.012
regulation of apoptotic signaling pathwayGO:200123310.012
cell type specific apoptotic processGO:009728540.012
regulation of meiosisGO:0040020940.012
meiotic chromosome segregationGO:00451321390.012
positive regulation of cellular protein catabolic processGO:190336430.012
muscle tissue developmentGO:006053710.012
Mouse
proteolysis involved in cellular protein catabolic processGO:0051603320.012
male sex differentiationGO:0046661860.012
epithelial cell morphogenesisGO:000338220.012
chemotaxisGO:00069351200.012
Mouse
response to starvationGO:0042594260.011
cell cycle g1 s phase transitionGO:004484320.011
dna repairGO:0006281230.011
g1 s transition of mitotic cell cycleGO:000008220.011
regulation of transportGO:0051049910.011
protein oligomerizationGO:005125940.011
Fly
regulation of kinase activityGO:0043549290.011
carboxylic acid metabolic processGO:0019752340.011
peptidyl amino acid modificationGO:0018193580.011
ribonucleoside monophosphate catabolic processGO:0009158280.011
Human Mouse
regulation of cellular ketone metabolic processGO:001056530.011
negative regulation of response to stimulusGO:0048585730.011
digestive tract morphogenesisGO:0048546760.011
Zebrafish Fly
organic substance transportGO:00717021130.011
Human
sensory organ morphogenesisGO:009059620.011
regulation of cell deathGO:0010941650.011
purine ribonucleoside metabolic processGO:0046128920.011
Human Mouse
dna geometric changeGO:003239230.011
muscle cell developmentGO:00550011580.011
positive regulation of cell communicationGO:0010647690.010
regulation of cell migrationGO:0030334550.010
gastrulationGO:0007369580.010
regulation of hydrolase activityGO:0051336450.010
regulation of protein modification processGO:0031399460.010
regulation of protein catabolic processGO:0042176130.010
carbohydrate metabolic processGO:0005975340.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.010
negative regulation of cellular biosynthetic processGO:0031327650.010
organic acid metabolic processGO:0006082470.010
regulation of vulval developmentGO:00400282480.010
maintenance of protein location in cellGO:0032507120.010
Fly
regulation of organ morphogenesisGO:200002740.010
Zebrafish
positive regulation of proteasomal protein catabolic processGO:190180010.010
regulation of nematode larval developmentGO:00610622600.010
rna transportGO:005065830.010

nmy-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart diseaseDOID:11400.033
cardiovascular system diseaseDOID:128700.033
myopathyDOID:42300.033
cardiomyopathyDOID:005070000.033
muscular diseaseDOID:008000000.033
disease of anatomical entityDOID:700.033
Human
muscle tissue diseaseDOID:6600.033
musculoskeletal system diseaseDOID:1700.033
cancerDOID:16200.027
disease of cellular proliferationDOID:1456600.027
organ system cancerDOID:005068600.011