Caenorhabditis elegans

50 known processes

let-99 (CELE_K08E7.3)

Protein LET-99

let-99 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.981
embryo development ending in birth or egg hatchingGO:000979229920.915
cell cycleGO:00070495260.784
female gamete generationGO:00072922540.758
single organism organelle organizationGO:19025895010.742
meiotic cell cycle processGO:19030461700.715
post embryonic developmentGO:000979121520.709
sexual reproductionGO:00199535460.669
germ cell developmentGO:00072813510.652
genitalia developmentGO:00488067410.646
single organism reproductive processGO:004470211960.636
oogenesisGO:00484772290.633
microtubule based processGO:00070171820.631
cellular process involved in reproduction in multicellular organismGO:00224123510.618
cell cycle processGO:00224024820.595
multicellular organism reproductionGO:00325048190.569
sex differentiationGO:00075489090.546
meiotic chromosome segregationGO:00451321390.540
locomotionGO:004001116340.539
organelle organizationGO:00069967830.519
reproductive system developmentGO:00614588500.517
apoptotic processGO:00069154780.505
multicellular organismal reproductive processGO:00486098150.497
chromosome segregationGO:00070591800.482
developmental process involved in reproductionGO:000300611650.474
meiotic cell cycleGO:00513213350.462
establishment of organelle localizationGO:00516561230.440
regulation of nematode larval developmentGO:00610622600.440
gamete generationGO:00072764610.428
macromolecule catabolic processGO:00090572020.393
deathGO:00162655470.393
organelle localizationGO:00516401270.361
cell developmentGO:00484686960.351
body morphogenesisGO:00101716200.333
gonad developmentGO:00084068400.325
agingGO:00075688120.322
cell deathGO:00082195470.321
development of primary sexual characteristicsGO:00451378400.313
programmed cell deathGO:00125015000.300
vesicle mediated transportGO:00161928520.296
meiotic nuclear divisionGO:00071263000.293
multicellular organismal agingGO:00102598120.290
determination of adult lifespanGO:00083408120.283
endocytosisGO:00068978190.282
macromolecular complex subunit organizationGO:00439333200.282
cytoskeleton organizationGO:00070103390.273
chromosome organization involved in meiosisGO:0070192250.262
negative regulation of biological processGO:00485195670.261
vulval developmentGO:00400253330.258
regulation of cell cycleGO:00517261940.256
organelle fissionGO:00482853630.251
cell motilityGO:00488703130.232
transportGO:000681010930.217
establishment of localizationGO:005123411710.207
regulation of meiotic cell cycleGO:00514451360.200
hermaphrodite genitalia developmentGO:00400357340.195
cellular component biogenesisGO:00440852970.194
multi organism reproductive processGO:00447038670.189
mitotic cell cycle processGO:19030471940.189
organic substance catabolic processGO:19015752940.188
single fertilizationGO:0007338610.185
regulation of mitotic cell cycleGO:0007346760.184
single organism signalingGO:00447004010.183
cell divisionGO:00513012620.178
catabolic processGO:00090563180.176
signal transductionGO:00071653170.173
macromolecule localizationGO:00330367710.173
regulation of multicellular organismal processGO:00512397260.172
regulation of vulval developmentGO:00400282480.166
cell migrationGO:00164773060.163
protein complex subunit organizationGO:00718222800.158
regulation of biological qualityGO:00650087410.156
regulation of macromolecule metabolic processGO:00602554210.147
organ developmentGO:004851311020.136
fertilizationGO:0009566630.132
defense responseGO:00069522960.129
regulation of phosphate metabolic processGO:0019220810.124
chromosome organizationGO:00512761040.124
localization of cellGO:00516743130.120
nucleic acid metabolic processGO:00903042990.119
reproductive structure developmentGO:00486088500.116
gene expressionGO:00104674120.115
phosphorylationGO:00163101160.113
ovipositionGO:00189913640.112
neuron differentiationGO:00301822170.108
regulation of gene expressionGO:00104683660.108
receptor mediated endocytosisGO:00068987150.108
regulation of cellular component organizationGO:00511282480.103
post embryonic organ developmentGO:00485693360.102
organelle assemblyGO:00709252140.101
negative regulation of developmental processGO:00510932270.100
oocyte developmentGO:0048599440.099
dna metabolic processGO:0006259740.099
regulation of cell cycle processGO:00105641450.098
cellular protein modification processGO:00064642070.097
cellular localizationGO:00516413600.095
regulation of multicellular organismal developmentGO:20000263170.095
protein metabolic processGO:00195384220.094
negative regulation of multicellular organismal processGO:00512412360.092
oocyte differentiationGO:0009994450.088
negative regulation of metabolic processGO:00098922400.088
negative regulation of nematode larval developmentGO:00610642080.086
establishment of localization in cellGO:00516493180.086
regulation of organelle organizationGO:00330431640.085
negative regulation of post embryonic developmentGO:00485812080.085
nucleobase containing compound catabolic processGO:00346551140.084
protein modification processGO:00362112070.083
regulation of metabolic processGO:00192224780.083
macromolecular complex assemblyGO:00650031930.082
cellular biosynthetic processGO:00442493150.082
establishment of spindle localizationGO:0051293510.081
actin filament based processGO:00300291910.080
developmental growthGO:00485894120.079
multicellular organismal reproductive behaviorGO:00330573840.078
organic substance biosynthetic processGO:19015763230.078
neuron projection morphogenesisGO:00488121140.077
secretion by cellGO:00329401380.076
maintenance of locationGO:00512355800.074
regulation of developmental processGO:00507936840.074
lipid storageGO:00199155650.073
purine containing compound metabolic processGO:0072521950.073
lipid localizationGO:00108765730.072
posttranscriptional regulation of gene expressionGO:00106081660.071
generation of neuronsGO:00486992350.071
regulation of macromolecule biosynthetic processGO:00105561890.070
neurogenesisGO:00220082360.069
regulation of post embryonic developmentGO:00485802600.069
response to biotic stimulusGO:00096071010.068
phosphorus metabolic processGO:00067932320.068
signalingGO:00230524010.066
regulation of cellular biosynthetic processGO:00313261890.065
cellular protein metabolic processGO:00442672790.063
cellular catabolic processGO:00442481990.063
regulation of response to stimulusGO:00485832430.063
regulation of cell divisionGO:00513021420.062
single organism localizationGO:19025785180.062
nucleobase containing compound metabolic processGO:00061394060.061
cellular component assemblyGO:00226072930.061
cell surface receptor signaling pathwayGO:00071661490.060
positive regulation of multicellular organism growthGO:00400183520.060
biosynthetic processGO:00090583230.059
reproductive behaviorGO:00190983870.059
positive regulation of cell cycleGO:0045787550.058
neuron developmentGO:00486661990.058
positive regulation of cellular processGO:00485223320.056
enzyme linked receptor protein signaling pathwayGO:0007167500.056
phosphate containing compound metabolic processGO:00067962320.056
cell projection organizationGO:00300302310.055
positive regulation of developmental processGO:00510944080.054
regulation of gene expression epigeneticGO:00400291630.051
sister chromatid segregationGO:0000819460.051
cellular component movementGO:00069283880.050
mitotic nuclear divisionGO:0007067890.050
positive regulation of macromolecule metabolic processGO:00106041490.048
cellular macromolecule catabolic processGO:0044265730.048
multi multicellular organism processGO:00447063900.047
regulation of signalingGO:00230511720.047
pattern specification processGO:0007389590.046
growthGO:00400075620.046
regulation of signal transductionGO:00099661350.046
regulation of growthGO:00400084090.046
regulation of multi organism processGO:0043900690.045
cellular macromolecule biosynthetic processGO:00346452470.045
cellular protein complex assemblyGO:00436231780.045
regulation of multicellular organism growthGO:00400143730.045
protein localizationGO:00081042050.044
cellular component morphogenesisGO:00329893180.044
cellular macromolecular complex assemblyGO:00346221840.044
spindle localizationGO:0051653510.044
establishment of cell polarityGO:0030010460.044
multi organism behaviorGO:00517053890.043
positive regulation of growthGO:00459273690.043
regulation of mitosisGO:0007088180.042
single organism catabolic processGO:00447121290.042
response to organic substanceGO:00100331310.042
response to external stimulusGO:00096052890.042
rna metabolic processGO:00160702280.041
protein catabolic processGO:00301631620.041
molting cycleGO:00423032810.040
positive regulation of multicellular organismal processGO:00512404170.039
aromatic compound catabolic processGO:00194391160.039
cytokinesisGO:0000910800.038
response to other organismGO:00517071010.038
multicellular organism growthGO:00352643850.038
posttranscriptional gene silencingGO:00164411430.037
regulation of nuclear divisionGO:00517831150.037
protein phosphorylationGO:0006468850.037
negative regulation of cellular processGO:00485232390.037
cellular nitrogen compound catabolic processGO:00442701190.037
regulation of cell communicationGO:00106461760.036
mitotic sister chromatid segregationGO:0000070380.036
behaviorGO:00076105270.036
negative regulation of gene expressionGO:00106292170.035
regulation of localizationGO:00328791940.035
macromolecule biosynthetic processGO:00090592500.034
protein complex biogenesisGO:00702711860.034
cell cell signalingGO:00072671180.033
anatomical structure formation involved in morphogenesisGO:00486462500.033
cellular response to stressGO:00335541620.033
cell maturationGO:0048469260.033
defense response to bacteriumGO:0042742860.032
negative regulation of cell cycleGO:0045786530.032
nucleobase containing compound biosynthetic processGO:00346541840.032
protein complex assemblyGO:00064611860.031
regulation of cellular metabolic processGO:00313233050.031
regulation of developmental growthGO:00486383890.031
positive regulation of developmental growthGO:00486393540.030
organophosphate metabolic processGO:00196371250.030
spindle organizationGO:0007051920.030
synaptic transmissionGO:00072681060.029
hermaphrodite germ line sex determinationGO:0040021480.029
single organism cellular localizationGO:1902580720.029
regulation of cellular macromolecule biosynthetic processGO:20001121880.029
cell fate commitmentGO:00451651390.029
negative regulation of macromolecule metabolic processGO:00106052290.028
cell morphogenesisGO:00009021630.028
response to external biotic stimulusGO:00432071010.028
actin cytoskeleton organizationGO:00300361840.028
rna interferenceGO:00162461370.027
negative regulation of signal transductionGO:0009968600.027
carbohydrate derivative metabolic processGO:19011351410.027
regulation of phosphorylationGO:0042325450.027
regulation of protein metabolic processGO:0051246810.026
microtubule polymerization or depolymerizationGO:0031109220.026
multi organism reproductive behaviorGO:00447053870.026
inductive cell migrationGO:00400391450.025
regulation of meiosisGO:0040020940.025
regulation of phosphorus metabolic processGO:0051174810.025
rna localizationGO:000640330.025
ribosome biogenesisGO:004225440.025
regulation of catalytic activityGO:0050790780.025
purine ribonucleoside triphosphate metabolic processGO:0009205870.025
female meiotic divisionGO:0007143170.025
glycosyl compound metabolic processGO:19016571000.024
single organism transportGO:00447654470.024
negative regulation of vulval developmentGO:00400272060.024
organophosphate catabolic processGO:0046434810.024
regulation of locomotionGO:00400121610.024
pole plasm assemblyGO:000731520.023
cell cycle switching mitotic to meiotic cell cycleGO:0051728350.023
organic cyclic compound catabolic processGO:19013611190.023
establishment or maintenance of cell polarityGO:0007163630.023
regulation of reproductive processGO:2000241660.023
establishment of mitotic spindle orientationGO:0000132280.023
positive regulation of nitrogen compound metabolic processGO:00511731340.023
actomyosin structure organizationGO:00310321540.023
cell part morphogenesisGO:00329901520.022
embryonic morphogenesisGO:00485981520.022
cellular protein localizationGO:0034613750.021
protein oligomerizationGO:005125940.021
gene silencing by rnaGO:00310471430.021
apoptotic cell clearanceGO:00432771110.020
purine nucleotide catabolic processGO:0006195750.020
ribonucleoside triphosphate metabolic processGO:0009199870.020
gene silencingGO:00164581430.020
response to chemicalGO:00422213560.020
ribonucleotide metabolic processGO:0009259990.019
small molecule metabolic processGO:00442811860.019
macromolecule modificationGO:00434122180.019
pronuclear migrationGO:0035046510.019
cell morphogenesis involved in differentiationGO:00009041120.019
regulation of transcription dna templatedGO:00063551640.019
neuron projection developmentGO:00311751870.019
purine containing compound catabolic processGO:0072523750.019
regulation of intracellular signal transductionGO:1902531770.019
sex determinationGO:0007530600.019
nucleoside phosphate catabolic processGO:1901292770.019
olfactory behaviorGO:0042048270.019
heterocycle catabolic processGO:00467001190.019
ribonucleoside triphosphate catabolic processGO:0009203720.018
nucleotide catabolic processGO:0009166770.018
regulation of cell motilityGO:2000145570.018
negative regulation of signalingGO:0023057610.018
secretionGO:00469031470.018
positive regulation of meiotic cell cycleGO:0051446470.018
regulation of translationGO:0006417190.018
posttranscriptional gene silencing by rnaGO:00351941430.018
regulation of cytoskeleton organizationGO:0051493410.018
negative regulation of cellular metabolic processGO:0031324950.018
regulation of primary metabolic processGO:00800902920.018
cell morphogenesis involved in neuron differentiationGO:00486671110.018
negative regulation of macromolecule biosynthetic processGO:0010558650.017
single organism biosynthetic processGO:0044711910.017
nervous system developmentGO:00073992530.017
membrane organizationGO:00610241350.017
system processGO:00030081360.017
apical junction assemblyGO:004329710.017
negative regulation of cellular component organizationGO:0051129330.017
cell proliferationGO:00082831160.017
protein modification by small protein conjugation or removalGO:0070647400.017
muscle contractionGO:0006936430.017
regulation of rna metabolic processGO:00512521730.016
muscle tissue developmentGO:006053710.016
establishment of spindle orientationGO:0051294340.016
regulation of transferase activityGO:0051338310.016
positive regulation of catalytic activityGO:0043085590.016
regulation of nucleobase containing compound metabolic processGO:00192192220.016
intracellular signal transductionGO:0035556960.016
spermatogenesisGO:0007283410.016
establishment of mitotic spindle localizationGO:0040001410.016
negative regulation of mitotic cell cycleGO:0045930420.016
nucleoside catabolic processGO:0009164780.016
cellular component assembly involved in morphogenesisGO:00109271830.015
oocyte constructionGO:000730820.015
muscle structure developmentGO:00610611910.015
regulation of chromosome segregationGO:0051983200.015
regulation of biosynthetic processGO:00098891890.015
meiotic sister chromatid segregationGO:0045144150.015
proteolysis involved in cellular protein catabolic processGO:0051603320.015
regulation of cell differentiationGO:0045595810.015
regulation of kinase activityGO:0043549290.015
cellular nitrogen compound biosynthetic processGO:00442711920.015
cellular response to chemical stimulusGO:00708871290.014
collagen and cuticulin based cuticle developmentGO:0040002990.014
ribonucleoside monophosphate metabolic processGO:0009161450.014
meiosis iGO:0007127190.014
cell cycle phase transitionGO:0044770190.014
nucleus localizationGO:0051647550.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.014
cellular protein catabolic processGO:0044257370.014
ribonucleoside metabolic processGO:0009119980.014
lipid metabolic processGO:0006629770.013
translationGO:0006412370.013
cuticle developmentGO:00423351000.013
polar body extrusion after meiotic divisionsGO:0040038140.013
regulation of cellular response to oxidative stressGO:190040710.013
regulation of nitrogen compound metabolic processGO:00511712220.013
myofibril assemblyGO:00302391540.013
nucleoside phosphate metabolic processGO:00067531080.013
male gamete generationGO:0048232410.013
purine nucleoside metabolic processGO:0042278920.013
defense response to gram negative bacteriumGO:0050829640.013
ion transportGO:00068111130.013
germ line sex determinationGO:0018992510.013
dendrite developmentGO:0016358420.013
purine nucleoside catabolic processGO:0006152750.013
organic substance transportGO:00717021130.013
purine nucleoside monophosphate catabolic processGO:0009128280.012
histone h3 k27 demethylationGO:007155730.012
mitotic spindle organizationGO:0007052810.012
mitotic cell cycle phase transitionGO:0044772130.012
cell projection morphogenesisGO:00488581480.012
purine ribonucleoside metabolic processGO:0046128920.012
membrane invaginationGO:0010324980.012
glycosyl compound catabolic processGO:1901658790.012
cellular response to dna damage stimulusGO:0006974410.012
muscle cell differentiationGO:00426921710.012
axis specificationGO:0009798230.012
engulfment of apoptotic cellGO:0043652940.012
regulation of apoptotic signaling pathwayGO:200123310.011
regulation of lipid metabolic processGO:001921640.011
regulation of cell proliferationGO:00421271050.011
purine nucleoside monophosphate metabolic processGO:0009126430.011
regulation of microtubule cytoskeleton organizationGO:0070507210.011
oocyte axis specificationGO:000730920.011
positive regulation of biosynthetic processGO:00098911090.011
cellular macromolecule localizationGO:0070727750.011
ribonucleotide catabolic processGO:0009261750.011
phagocytosis engulfmentGO:0006911980.011
nucleobase containing small molecule metabolic processGO:00550861150.011
germline cell cycle switching mitotic to meiotic cell cycleGO:0051729350.011
purine ribonucleoside triphosphate catabolic processGO:0009207720.011
response to bacteriumGO:0009617860.011
defense response to other organismGO:00985421000.011
mesodermal cell migrationGO:000807890.011
nucleoside triphosphate metabolic processGO:0009141870.011
neurological system processGO:0050877530.011
immune responseGO:00069551920.010
mitotic sister chromatid separationGO:0051306130.010
regulation of epithelial cell differentiationGO:003085640.010
negative regulation of neurogenesisGO:005076840.010
purine ribonucleotide metabolic processGO:0009150950.010

let-99 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of mental healthDOID:15000.010
intellectual disabilityDOID:105900.010
specific developmental disorderDOID:006003800.010
developmental disorder of mental healthDOID:006003700.010