Caenorhabditis elegans

56 known processes

smc-4 (CELE_F35G12.8)

Protein SMC-4

smc-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic nuclear divisionGO:00071263000.941
Mouse
meiotic cell cycleGO:00513213350.931
Mouse
meiotic cell cycle processGO:19030461700.920
Mouse
mitotic nuclear divisionGO:0007067890.903
mitotic cell cycle processGO:19030471940.899
embryo developmentGO:000979030520.898
embryo development ending in birth or egg hatchingGO:000979229920.845
organelle fissionGO:00482853630.827
cell cycle processGO:00224024820.799
cell cycleGO:00070495260.630
post embryonic developmentGO:000979121520.604
single organism organelle organizationGO:19025895010.567
chromosome segregationGO:00070591800.541
nucleoside triphosphate catabolic processGO:0009143720.529
sexual reproductionGO:00199535460.511
cellular process involved in reproduction in multicellular organismGO:00224123510.494
meiotic chromosome segregationGO:00451321390.484
Mouse
organelle organizationGO:00069967830.475
endocytosisGO:00068978190.444
single organism localizationGO:19025785180.424
regulation of macromolecule metabolic processGO:00602554210.395
Worm
receptor mediated endocytosisGO:00068987150.381
gamete generationGO:00072764610.372
establishment of localizationGO:005123411710.360
reproductive system developmentGO:00614588500.348
agingGO:00075688120.336
phosphate containing compound metabolic processGO:00067962320.326
female gamete generationGO:00072922540.317
dna metabolic processGO:0006259740.301
Human Mouse
programmed cell deathGO:00125015000.301
germ cell developmentGO:00072813510.293
transportGO:000681010930.288
multicellular organism reproductionGO:00325048190.279
multicellular organismal reproductive processGO:00486098150.279
cell deathGO:00082195470.278
organ developmentGO:004851311020.275
genitalia developmentGO:00488067410.269
locomotionGO:004001116340.254
establishment of organelle localizationGO:00516561230.245
cellular localizationGO:00516413600.234
anatomical structure formation involved in morphogenesisGO:00486462500.232
chromosome organization involved in meiosisGO:0070192250.227
Mouse
neurogenesisGO:00220082360.215
Worm
purine nucleoside triphosphate catabolic processGO:0009146720.214
establishment of localization in cellGO:00516493180.213
vesicle mediated transportGO:00161928520.209
determination of adult lifespanGO:00083408120.203
deathGO:00162655470.203
purine ribonucleotide metabolic processGO:0009150950.196
purine containing compound catabolic processGO:0072523750.196
multicellular organismal agingGO:00102598120.195
purine nucleotide catabolic processGO:0006195750.192
cytoskeleton organizationGO:00070103390.190
gene expressionGO:00104674120.190
Worm
nucleic acid metabolic processGO:00903042990.184
Human Mouse
body morphogenesisGO:00101716200.183
Worm
reproductive structure developmentGO:00486088500.179
nucleoside phosphate catabolic processGO:1901292770.178
macromolecule localizationGO:00330367710.177
single organism reproductive processGO:004470211960.168
regulation of gene expressionGO:00104683660.164
Worm
cell developmentGO:00484686960.163
Worm
nucleoside triphosphate metabolic processGO:0009141870.156
carbohydrate derivative metabolic processGO:19011351410.153
positive regulation of nucleic acid templated transcriptionGO:19035081020.151
gonad developmentGO:00084068400.145
oogenesisGO:00484772290.144
spindle organizationGO:0007051920.142
ribonucleoside triphosphate metabolic processGO:0009199870.140
dna duplex unwindingGO:003250830.138
positive regulation of cellular processGO:00485223320.137
apoptotic processGO:00069154780.134
sex differentiationGO:00075489090.131
hermaphrodite genitalia developmentGO:00400357340.127
generation of neuronsGO:00486992350.125
Worm
organelle assemblyGO:00709252140.125
organelle localizationGO:00516401270.125
positive regulation of macromolecule biosynthetic processGO:00105571090.125
neuroblast divisionGO:005505790.123
negative regulation of multicellular organismal processGO:00512412360.120
organonitrogen compound metabolic processGO:19015641510.119
cell morphogenesisGO:00009021630.118
nucleobase containing small molecule metabolic processGO:00550861150.117
positive regulation of rna metabolic processGO:00512541030.116
nucleobase containing compound metabolic processGO:00061394060.116
Human Mouse
regulation of developmental processGO:00507936840.116
dna recombinationGO:0006310190.112
developmental process involved in reproductionGO:000300611650.112
purine ribonucleoside triphosphate catabolic processGO:0009207720.110
ribonucleotide metabolic processGO:0009259990.107
purine nucleoside metabolic processGO:0042278920.106
ribonucleotide catabolic processGO:0009261750.106
growthGO:00400075620.105
organonitrogen compound catabolic processGO:1901565900.104
rna metabolic processGO:00160702280.100
nucleotide metabolic processGO:00091171080.100
attachment of mitotic spindle microtubules to kinetochoreGO:005131560.099
positive regulation of neurogenesisGO:005076940.096
negative regulation of developmental processGO:00510932270.094
glycosyl compound metabolic processGO:19016571000.093
protein complex subunit organizationGO:00718222800.091
Mouse
ribonucleoside triphosphate catabolic processGO:0009203720.091
negative regulation of biological processGO:00485195670.091
cellular response to stressGO:00335541620.090
localization of cellGO:00516743130.090
negative regulation of macromolecule metabolic processGO:00106052290.090
neuron differentiationGO:00301822170.089
Worm
cell fate commitmentGO:00451651390.088
organophosphate catabolic processGO:0046434810.088
cell divisionGO:00513012620.087
microtubule based processGO:00070171820.085
purine ribonucleotide catabolic processGO:0009154750.084
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.084
cellular component movementGO:00069283880.083
sister chromatid segregationGO:0000819460.083
single organism transportGO:00447654470.083
cellular component morphogenesisGO:00329893180.082
macromolecular complex subunit organizationGO:00439333200.080
Mouse
regulation of transcription dna templatedGO:00063551640.080
purine nucleoside catabolic processGO:0006152750.079
nucleotide catabolic processGO:0009166770.078
dna geometric changeGO:003239230.077
regulation of biological qualityGO:00650087410.076
regulation of vulval developmentGO:00400282480.075
organic substance catabolic processGO:19015752940.075
rna localizationGO:000640330.074
multicellular organism growthGO:00352643850.074
positive regulation of multicellular organismal processGO:00512404170.074
heterocycle catabolic processGO:00467001190.072
regulation of post embryonic developmentGO:00485802600.072
homeostatic processGO:0042592510.071
macromolecular complex assemblyGO:00650031930.071
purine nucleotide metabolic processGO:0006163950.070
regulation of multicellular organismal processGO:00512397260.069
positive regulation of biosynthetic processGO:00098911090.068
purine containing compound metabolic processGO:0072521950.067
ribose phosphate metabolic processGO:0019693990.067
cell migrationGO:00164773060.067
maintenance of locationGO:00512355800.067
regulation of metabolic processGO:00192224780.067
Worm
ovipositionGO:00189913640.065
Worm
development of primary sexual characteristicsGO:00451378400.064
cell motilityGO:00488703130.063
regulation of nematode larval developmentGO:00610622600.062
ribonucleoside catabolic processGO:0042454770.062
signal transductionGO:00071653170.060
positive regulation of developmental processGO:00510944080.060
lipid storageGO:00199155650.060
negative regulation of nitrogen compound metabolic processGO:0051172630.059
catabolic processGO:00090563180.059
developmental growthGO:00485894120.058
purine ribonucleoside catabolic processGO:0046130750.058
regulation of mitotic cell cycleGO:0007346760.058
purine ribonucleoside metabolic processGO:0046128920.057
cellular macromolecular complex assemblyGO:00346221840.057
regulation of multicellular organismal developmentGO:20000263170.056
protein catabolic processGO:00301631620.056
organophosphate metabolic processGO:00196371250.055
positive regulation of transcription dna templatedGO:00458931020.054
small molecule metabolic processGO:00442811860.054
macromolecule biosynthetic processGO:00090592500.053
protein metabolic processGO:00195384220.053
nucleoside catabolic processGO:0009164780.053
molting cycleGO:00423032810.052
cellular nitrogen compound biosynthetic processGO:00442711920.052
response to chemicalGO:00422213560.052
carbohydrate derivative catabolic processGO:1901136820.052
mitotic spindle organizationGO:0007052810.051
single organism signalingGO:00447004010.051
regulation of cellular biosynthetic processGO:00313261890.051
glycosyl compound catabolic processGO:1901658790.050
purine ribonucleoside triphosphate metabolic processGO:0009205870.049
nervous system developmentGO:00073992530.049
Worm
single organism catabolic processGO:00447121290.049
nucleoside phosphate metabolic processGO:00067531080.048
nucleoside metabolic processGO:0009116990.046
cellular component biogenesisGO:00440852970.046
protein complex assemblyGO:00064611860.045
nucleus organizationGO:0006997380.045
regulation of cellular metabolic processGO:00313233050.045
polar body extrusion after meiotic divisionsGO:0040038140.045
cellular macromolecule biosynthetic processGO:00346452470.044
regulation of multicellular organism growthGO:00400143730.044
ribosome biogenesisGO:004225440.043
lipid localizationGO:00108765730.042
response to external stimulusGO:00096052890.042
cell part morphogenesisGO:00329901520.042
regulation of locomotionGO:00400121610.041
biosynthetic processGO:00090583230.040
regulation of developmental growthGO:00486383890.040
organic substance transportGO:00717021130.040
cellular catabolic processGO:00442481990.039
cellular component assemblyGO:00226072930.038
regulation of cell cycle processGO:00105641450.038
organic substance biosynthetic processGO:19015763230.037
regulation of rna biosynthetic processGO:20011411650.037
regulation of localizationGO:00328791940.037
meiosis iGO:0007127190.037
regulation of cell differentiationGO:0045595810.037
post embryonic organ developmentGO:00485693360.037
regulation of cell divisionGO:00513021420.037
regulation of nucleic acid templated transcriptionGO:19035061650.036
aromatic compound catabolic processGO:00194391160.036
regulation of cell cycleGO:00517261940.036
regulation of nitrogen compound metabolic processGO:00511712220.036
positive regulation of cellular metabolic processGO:00313251780.035
rna biosynthetic processGO:00327741690.034
phosphorus metabolic processGO:00067932320.034
cellular biosynthetic processGO:00442493150.034
protein localizationGO:00081042050.034
attachment of spindle microtubules to kinetochoreGO:000860880.034
negative regulation of gene expressionGO:00106292170.034
pattern specification processGO:0007389590.033
multi organism reproductive behaviorGO:00447053870.033
Worm
female meiotic divisionGO:0007143170.033
multi organism behaviorGO:00517053890.033
Worm
positive regulation of multicellular organism growthGO:00400183520.032
regulation of mitosisGO:0007088180.032
positive regulation of developmental growthGO:00486393540.032
positive regulation of embryonic developmentGO:004001930.032
dna repairGO:0006281230.032
cytoskeleton dependent cytokinesisGO:0061640350.032
cellular response to dna damage stimulusGO:0006974410.031
regulation of transcription from rna polymerase ii promoterGO:00063571450.031
regulation of phosphorus metabolic processGO:0051174810.031
anterior posterior pattern specificationGO:0009952270.031
positive regulation of nucleobase containing compound metabolic processGO:00459351340.031
cell projection morphogenesisGO:00488581480.031
single organism cellular localizationGO:1902580720.031
chromosome organizationGO:00512761040.031
tissue developmentGO:00098881120.030
ras protein signal transductionGO:0007265310.030
positive regulation of metabolic processGO:00098931870.029
mitotic sister chromatid segregationGO:0000070380.029
negative regulation of cellular processGO:00485232390.029
regulation of growthGO:00400084090.029
positive regulation of cellular biosynthetic processGO:00313281090.029
single organism biosynthetic processGO:0044711910.029
protein complex biogenesisGO:00702711860.029
regulation of catalytic activityGO:0050790780.028
nucleic acid templated transcriptionGO:00976591690.028
purine nucleoside triphosphate metabolic processGO:0009144870.028
multi organism reproductive processGO:00447038670.028
multi multicellular organism processGO:00447063900.027
Worm
cellular protein metabolic processGO:00442672790.027
regulation of neuron differentiationGO:0045664400.027
asymmetric cell divisionGO:0008356360.027
establishment of cell polarityGO:0030010460.026
muscle tissue developmentGO:006053710.026
kinetochore organizationGO:005138370.026
Mouse
digestive system developmentGO:00551231220.026
vulval developmentGO:00400253330.025
embryonic morphogenesisGO:00485981520.025
organic cyclic compound catabolic processGO:19013611190.025
positive regulation of nitrogen compound metabolic processGO:00511731340.025
rna interferenceGO:00162461370.025
nitrogen compound transportGO:0071705490.025
cell proliferationGO:00082831160.024
negative regulation of cellular metabolic processGO:0031324950.024
regionalizationGO:0003002310.024
guanosine containing compound metabolic processGO:1901068490.024
macromolecule modificationGO:00434122180.024
sensory organ morphogenesisGO:009059620.023
inductive cell migrationGO:00400391450.023
establishment of spindle localizationGO:0051293510.023
regulation of cellular component organizationGO:00511282480.023
molting cycle collagen and cuticulin based cuticleGO:00189962810.023
posttranscriptional regulation of gene expressionGO:00106081660.023
intracellular signal transductionGO:0035556960.023
regulation of phosphate metabolic processGO:0019220810.022
regulation of chromosome segregationGO:0051983200.022
aromatic compound biosynthetic processGO:00194381920.022
cytokinesisGO:0000910800.022
cellular protein localizationGO:0034613750.022
negative regulation of transcription dna templatedGO:0045892530.021
actomyosin structure organizationGO:00310321540.021
regulation of molecular functionGO:0065009890.021
establishment of rna localizationGO:005123630.021
regulation of microtubule cytoskeleton organizationGO:0070507210.021
proteasomal protein catabolic processGO:0010498200.021
atp metabolic processGO:0046034420.020
reproductive behaviorGO:00190983870.020
Worm
macromolecule catabolic processGO:00090572020.020
regulation of nucleobase containing compound metabolic processGO:00192192220.020
positive regulation of gene expressionGO:00106281120.020
positive regulation of growthGO:00459273690.019
cell projection organizationGO:00300302310.019
Worm
actin filament based processGO:00300291910.019
positive regulation of phosphorus metabolic processGO:0010562560.019
single organism intracellular transportGO:1902582700.019
positive regulation of cell deathGO:0010942380.019
male gamete generationGO:0048232410.019
nucleic acid transportGO:005065730.019
gene silencing by rnaGO:00310471430.019
positive regulation of rna biosynthetic processGO:19026801020.019
pronuclear migrationGO:0035046510.019
negative regulation of metabolic processGO:00098922400.018
cellular nitrogen compound catabolic processGO:00442701190.018
rna transportGO:005065830.018
cell morphogenesis involved in differentiationGO:00009041120.018
microtubule cytoskeleton organization involved in mitosisGO:1902850120.018
ribonucleoside metabolic processGO:0009119980.018
nucleobase containing compound catabolic processGO:00346551140.018
heterocycle biosynthetic processGO:00181301870.018
regulation of cellular amine metabolic processGO:003323800.018
regulation of meiotic cell cycleGO:00514451360.018
ion transportGO:00068111130.018
epithelial cell proliferationGO:005067310.018
positive regulation of macromolecule metabolic processGO:00106041490.017
negative regulation of nematode larval developmentGO:00610642080.017
nucleoside monophosphate metabolic processGO:0009123460.017
ribonucleoside monophosphate metabolic processGO:0009161450.017
regulation of primary metabolic processGO:00800902920.017
regulation of organelle organizationGO:00330431640.017
positive regulation of stem cell differentiationGO:200073810.017
cellular protein complex assemblyGO:00436231780.017
spermatogenesisGO:0007283410.017
multicellular organismal reproductive behaviorGO:00330573840.016
Worm
purine nucleoside monophosphate catabolic processGO:0009128280.016
spindle localizationGO:0051653510.016
protein modification processGO:00362112070.016
regulation of nuclear divisionGO:00517831150.016
regulation of cellular ketone metabolic processGO:001056530.016
regulation of cell proliferationGO:00421271050.016
posttranscriptional gene silencing by rnaGO:00351941430.016
intracellular transportGO:0046907770.016
nuclear migrationGO:0007097540.016
signalingGO:00230524010.016
cellular macromolecule localizationGO:0070727750.016
behaviorGO:00076105270.015
Worm
regulation of multi organism processGO:0043900690.015
digestive tract developmentGO:00485651220.015
negative regulation of macromolecule biosynthetic processGO:0010558650.015
epithelial tube morphogenesisGO:006056210.015
positive regulation of phosphate metabolic processGO:0045937560.015
negative regulation of vulval developmentGO:00400272060.015
oocyte differentiationGO:0009994450.015
cellular component assembly involved in morphogenesisGO:00109271830.015
apoptotic cell clearanceGO:00432771110.015
posttranscriptional gene silencingGO:00164411430.015
positive regulation of chromosome organizationGO:200125220.014
rrna processingGO:000636430.014
ribonucleoprotein complex assemblyGO:002261840.014
specification of axis polarityGO:0065001130.014
membrane organizationGO:00610241350.014
negative regulation of gene expression epigeneticGO:004581420.014
tissue morphogenesisGO:0048729650.014
mitotic sister chromatid separationGO:0051306130.014
regulation of attachment of spindle microtubules to kinetochoreGO:005198820.014
epithelium developmentGO:0060429680.014
digestive tract morphogenesisGO:0048546760.014
negative regulation of post embryonic developmentGO:00485812080.013
response to abiotic stimulusGO:00096281520.013
amine metabolic processGO:0009308150.013
protein phosphorylationGO:0006468850.013
positive regulation of catalytic activityGO:0043085590.013
muscle cell developmentGO:00550011580.013
regulation of meiosisGO:0040020940.013
cellular response to organic substanceGO:00713101190.013
regenerationGO:003109940.013
regulation of cellular macromolecule biosynthetic processGO:20001121880.013
negative regulation of nucleic acid templated transcriptionGO:1903507530.012
regulation of phosphorylationGO:0042325450.012
regulation of protein localizationGO:0032880500.012
collagen and cuticulin based cuticle developmentGO:0040002990.012
innate immune responseGO:00450871900.012
organic acid metabolic processGO:0006082470.012
cellular protein catabolic processGO:0044257370.012
cellular amine metabolic processGO:0044106150.012
oocyte developmentGO:0048599440.012
carboxylic acid metabolic processGO:0019752340.012
myosin filament assemblyGO:00310341380.012
cell maturationGO:0048469260.012
positive regulation of cell cycleGO:0045787550.012
negative regulation of cellular biosynthetic processGO:0031327650.012
positive regulation of cell differentiationGO:004559780.012
protein oligomerizationGO:005125940.012
regulation of embryonic developmentGO:0045995160.012
phagocytosis engulfmentGO:0006911980.012
positive regulation of cellular protein catabolic processGO:190336430.012
negative regulation of signalingGO:0023057610.012
tube morphogenesisGO:0035239790.012
regulation of cellular amino acid metabolic processGO:000652100.012
response to external biotic stimulusGO:00432071010.012
response to organic substanceGO:00100331310.012
cellular ketone metabolic processGO:0042180140.012
engulfment of apoptotic cellGO:0043652940.011
positive regulation of cysteine type endopeptidase activityGO:200105630.011
regulation of transferase activityGO:0051338310.011
somatic stem cell divisionGO:004810390.011
fertilizationGO:0009566630.011
response to oxygen containing compoundGO:1901700440.011
response to other organismGO:00517071010.011
regulation of nucleoside metabolic processGO:0009118370.011
gtp metabolic processGO:0046039460.011
neuron projection developmentGO:00311751870.011
Worm
positive regulation of nucleoside metabolic processGO:0045979280.011
stem cell divisionGO:0017145180.011
negative regulation of neurogenesisGO:005076840.011
regulation of behaviorGO:0050795970.011
regulation of programmed cell deathGO:0043067500.011
neuron projection morphogenesisGO:00488121140.011
positive regulation of protein transportGO:005122240.011
chemosensory behaviorGO:0007635330.011
regulation of protein modification processGO:0031399460.011
myofibril assemblyGO:00302391540.011
regulation of biosynthetic processGO:00098891890.011
microtubule depolymerizationGO:0007019100.010
cellular protein modification processGO:00064642070.010
spindle assembly involved in mitosisGO:009030760.010
membrane invaginationGO:0010324980.010
embryonic pattern specificationGO:0009880210.010

smc-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
cardiovascular system diseaseDOID:128700.014
gastrointestinal system cancerDOID:311900.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012