Caenorhabditis elegans

32 known processes

mel-28 (CELE_C38D4.3)

Protein MEL-28

mel-28 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.873
sexual reproductionGO:00199535460.847
meiotic cell cycleGO:00513213350.814
organelle organizationGO:00069967830.794
cell cycle processGO:00224024820.768
meiotic nuclear divisionGO:00071263000.763
cell cycleGO:00070495260.759
establishment of localizationGO:005123411710.754
post embryonic developmentGO:000979121520.720
embryo development ending in birth or egg hatchingGO:000979229920.715
organ developmentGO:004851311020.691
meiotic cell cycle processGO:19030461700.661
neurogenesisGO:00220082360.623
gamete generationGO:00072764610.607
cell developmentGO:00484686960.601
meiotic chromosome segregationGO:00451321390.596
mitotic cell cycle processGO:19030471940.591
nucleobase containing compound metabolic processGO:00061394060.571
chromosome segregationGO:00070591800.548
organelle fissionGO:00482853630.525
regulation of multicellular organismal developmentGO:20000263170.500
kinetochore organizationGO:005138370.470
locomotionGO:004001116340.445
transportGO:000681010930.442
cellular process involved in reproduction in multicellular organismGO:00224123510.411
endocytosisGO:00068978190.407
cellular component morphogenesisGO:00329893180.404
positive regulation of nucleobase containing compound metabolic processGO:00459351340.381
nucleic acid metabolic processGO:00903042990.381
female gamete generationGO:00072922540.374
regulation of multicellular organismal processGO:00512397260.364
single organism localizationGO:19025785180.356
regulation of developmental processGO:00507936840.349
programmed cell deathGO:00125015000.344
cellular response to stressGO:00335541620.325
developmental process involved in reproductionGO:000300611650.323
single organism organelle organizationGO:19025895010.317
single organism reproductive processGO:004470211960.315
neuron developmentGO:00486661990.308
cellular localizationGO:00516413600.304
regulation of vulval developmentGO:00400282480.295
organelle localizationGO:00516401270.291
reproductive structure developmentGO:00486088500.288
positive regulation of rna metabolic processGO:00512541030.286
neuron projection morphogenesisGO:00488121140.281
gene expressionGO:00104674120.271
positive regulation of rna biosynthetic processGO:19026801020.269
cell projection organizationGO:00300302310.266
germ cell developmentGO:00072813510.261
nervous system developmentGO:00073992530.261
aromatic compound biosynthetic processGO:00194381920.260
oogenesisGO:00484772290.260
cellular component assemblyGO:00226072930.259
neuron differentiationGO:00301822170.259
growthGO:00400075620.257
positive regulation of nitrogen compound metabolic processGO:00511731340.256
establishment of organelle localizationGO:00516561230.254
deathGO:00162655470.247
multicellular organismal reproductive processGO:00486098150.247
positive regulation of macromolecule metabolic processGO:00106041490.244
regulation of cell cycle processGO:00105641450.244
phosphate containing compound metabolic processGO:00067962320.244
regulation of metabolic processGO:00192224780.239
regulation of nitrogen compound metabolic processGO:00511712220.236
apoptotic processGO:00069154780.230
response to chemicalGO:00422213560.229
multicellular organism reproductionGO:00325048190.227
macromolecular complex subunit organizationGO:00439333200.221
receptor mediated endocytosisGO:00068987150.218
mitotic nuclear divisionGO:0007067890.216
positive regulation of nucleic acid templated transcriptionGO:19035081020.214
response to external stimulusGO:00096052890.210
development of primary sexual characteristicsGO:00451378400.209
hermaphrodite genitalia developmentGO:00400357340.203
single organism transportGO:00447654470.200
generation of neuronsGO:00486992350.193
positive regulation of metabolic processGO:00098931870.190
reproductive system developmentGO:00614588500.185
protein localizationGO:00081042050.180
transcription dna templatedGO:00063511680.177
regulation of rna biosynthetic processGO:20011411650.177
regulation of primary metabolic processGO:00800902920.176
determination of adult lifespanGO:00083408120.174
vesicle mediated transportGO:00161928520.173
centromere complex assemblyGO:003450850.173
regulation of biological qualityGO:00650087410.172
regulation of biosynthetic processGO:00098891890.168
negative regulation of gene expression epigeneticGO:004581420.168
organophosphate metabolic processGO:00196371250.168
establishment of localization in cellGO:00516493180.166
vulval developmentGO:00400253330.165
cytoskeleton organizationGO:00070103390.163
regulation of cellular component organizationGO:00511282480.162
regulation of transcription from rna polymerase ii promoterGO:00063571450.156
protein metabolic processGO:00195384220.155
organic substance catabolic processGO:19015752940.152
cell morphogenesis involved in differentiationGO:00009041120.151
cellular component movementGO:00069283880.149
cell part morphogenesisGO:00329901520.145
positive regulation of biosynthetic processGO:00098911090.145
cellular component biogenesisGO:00440852970.140
sex differentiationGO:00075489090.140
cell morphogenesis involved in neuron differentiationGO:00486671110.139
macromolecule localizationGO:00330367710.135
cellular catabolic processGO:00442481990.134
protein modification processGO:00362112070.134
cell morphogenesisGO:00009021630.131
organelle assemblyGO:00709252140.129
positive regulation of cellular processGO:00485223320.128
organic cyclic compound biosynthetic processGO:19013621950.127
neuron projection developmentGO:00311751870.125
rna biosynthetic processGO:00327741690.123
regulation of cell communicationGO:00106461760.123
positive regulation of macromolecule biosynthetic processGO:00105571090.123
regulation of nematode larval developmentGO:00610622600.122
regulation of mitotic cell cycleGO:0007346760.121
macromolecule modificationGO:00434122180.119
attachment of mitotic spindle microtubules to kinetochoreGO:005131560.118
post embryonic organ developmentGO:00485693360.118
regulation of transcription dna templatedGO:00063551640.117
fertilizationGO:0009566630.115
regulation of cellular macromolecule biosynthetic processGO:20001121880.114
cellular protein metabolic processGO:00442672790.114
anatomical structure formation involved in morphogenesisGO:00486462500.114
axon developmentGO:00615641630.114
regulation of rna metabolic processGO:00512521730.112
cell cycle phase transitionGO:0044770190.112
catabolic processGO:00090563180.111
positive regulation of gene expressionGO:00106281120.109
cell deathGO:00082195470.108
carbohydrate derivative catabolic processGO:1901136820.107
purine nucleoside triphosphate metabolic processGO:0009144870.104
purine nucleotide metabolic processGO:0006163950.103
chromosome organizationGO:00512761040.103
tissue developmentGO:00098881120.103
attachment of spindle microtubules to kinetochoreGO:000860880.103
purine ribonucleoside triphosphate metabolic processGO:0009205870.102
nucleotide metabolic processGO:00091171080.102
multicellular organismal agingGO:00102598120.098
protein complex subunit organizationGO:00718222800.097
regulation of cell cycleGO:00517261940.096
nucleic acid templated transcriptionGO:00976591690.095
regulation of nucleobase containing compound metabolic processGO:00192192220.094
regulation of cellular metabolic processGO:00313233050.092
organic substance biosynthetic processGO:19015763230.092
negative regulation of cellular processGO:00485232390.091
rna metabolic processGO:00160702280.091
nucleobase containing small molecule metabolic processGO:00550861150.089
phosphorus metabolic processGO:00067932320.088
cell divisionGO:00513012620.086
chemotaxisGO:00069351200.085
regulation of cell divisionGO:00513021420.084
cellular protein modification processGO:00064642070.084
cellular nitrogen compound biosynthetic processGO:00442711920.083
cell migrationGO:00164773060.082
ribonucleotide metabolic processGO:0009259990.082
genitalia developmentGO:00488067410.082
cell motilityGO:00488703130.082
nucleobase containing compound catabolic processGO:00346551140.082
cellular macromolecular complex assemblyGO:00346221840.081
aromatic compound catabolic processGO:00194391160.081
organophosphate catabolic processGO:0046434810.080
multi organism reproductive processGO:00447038670.079
positive regulation of cellular metabolic processGO:00313251780.078
maintenance of locationGO:00512355800.077
regulation of signalingGO:00230511720.077
transcription from rna polymerase ii promoterGO:00063661490.077
agingGO:00075688120.076
regulation of macromolecule metabolic processGO:00602554210.075
asymmetric protein localizationGO:0008105350.074
taxisGO:00423301280.074
axonogenesisGO:00074091020.074
positive regulation of transcription dna templatedGO:00458931020.074
cellular response to dna damage stimulusGO:0006974410.073
localization of cellGO:00516743130.072
cellular protein localizationGO:0034613750.071
negative regulation of multicellular organismal processGO:00512412360.070
purine ribonucleoside metabolic processGO:0046128920.070
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.070
establishment of chromosome localizationGO:0051303100.068
developmental growthGO:00485894120.067
positive regulation of nucleoside metabolic processGO:0045979280.067
regulation of cell proliferationGO:00421271050.067
purine ribonucleoside catabolic processGO:0046130750.067
regulation of signal transductionGO:00099661350.067
protein complex biogenesisGO:00702711860.066
positive regulation of neurogenesisGO:005076940.066
biosynthetic processGO:00090583230.065
macromolecule biosynthetic processGO:00090592500.065
nucleoside phosphate catabolic processGO:1901292770.065
sister chromatid segregationGO:0000819460.065
regulation of macromolecule biosynthetic processGO:00105561890.064
regulation of cellular biosynthetic processGO:00313261890.064
gonad developmentGO:00084068400.063
membrane organizationGO:00610241350.062
actin cytoskeleton organizationGO:00300361840.062
chromosome organization involved in meiosisGO:0070192250.062
ribonucleoside catabolic processGO:0042454770.061
purine nucleoside triphosphate catabolic processGO:0009146720.061
lipid storageGO:00199155650.061
cellular nitrogen compound catabolic processGO:00442701190.061
body morphogenesisGO:00101716200.061
nucleoside triphosphate metabolic processGO:0009141870.060
heterocycle catabolic processGO:00467001190.059
cellular response to abiotic stimulusGO:007121440.059
sensory organ morphogenesisGO:009059620.059
negative regulation of metabolic processGO:00098922400.059
small molecule metabolic processGO:00442811860.057
positive regulation of developmental processGO:00510944080.057
response to abiotic stimulusGO:00096281520.057
negative regulation of biological processGO:00485195670.057
negative regulation of nematode larval developmentGO:00610642080.057
regulation of growthGO:00400084090.056
purine containing compound catabolic processGO:0072523750.055
purine ribonucleotide metabolic processGO:0009150950.054
single organism signalingGO:00447004010.054
positive regulation of gtpase activityGO:0043547280.054
purine nucleoside metabolic processGO:0042278920.054
negative regulation of vulval developmentGO:00400272060.052
positive regulation of cellular biosynthetic processGO:00313281090.052
mitotic sister chromatid segregationGO:0000070380.052
organonitrogen compound catabolic processGO:1901565900.052
actin filament based processGO:00300291910.052
signal transductionGO:00071653170.051
regulation of nucleic acid templated transcriptionGO:19035061650.051
organic cyclic compound catabolic processGO:19013611190.051
purine nucleoside catabolic processGO:0006152750.051
multicellular organismal reproductive behaviorGO:00330573840.051
regulation of post embryonic developmentGO:00485802600.050
gene silencingGO:00164581430.050
purine containing compound metabolic processGO:0072521950.049
negative regulation of response to stimulusGO:0048585730.049
positive regulation of nucleotide metabolic processGO:0045981280.049
tube morphogenesisGO:0035239790.049
nucleobase containing compound biosynthetic processGO:00346541840.049
ribose phosphate metabolic processGO:0019693990.048
ribonucleoside triphosphate metabolic processGO:0009199870.048
nucleoside phosphate metabolic processGO:00067531080.048
ras protein signal transductionGO:0007265310.048
single organism catabolic processGO:00447121290.047
regulation of response to stimulusGO:00485832430.047
signalingGO:00230524010.047
regulation of gene expressionGO:00104683660.047
regulation of developmental growthGO:00486383890.047
heterocycle biosynthetic processGO:00181301870.047
cellular biosynthetic processGO:00442493150.045
lipid localizationGO:00108765730.045
nucleoside triphosphate catabolic processGO:0009143720.045
negative regulation of developmental processGO:00510932270.045
chromosome localizationGO:0050000100.044
organ morphogenesisGO:0009887670.044
nucleoside metabolic processGO:0009116990.043
dna recombinationGO:0006310190.043
intracellular signal transductionGO:0035556960.043
positive regulation of developmental growthGO:00486393540.043
metaphase plate congressionGO:005131050.043
stem cell differentiationGO:004886370.042
cell proliferationGO:00082831160.041
macromolecule catabolic processGO:00090572020.039
posttranscriptional regulation of gene expressionGO:00106081660.038
regulation of organelle organizationGO:00330431640.038
regulation of purine nucleotide catabolic processGO:0033121350.038
head developmentGO:006032210.038
digestive system developmentGO:00551231220.036
guanosine containing compound catabolic processGO:1901069480.036
positive regulation of growthGO:00459273690.036
cell projection morphogenesisGO:00488581480.035
wnt signaling pathwayGO:0016055270.034
purine nucleotide catabolic processGO:0006195750.034
ribonucleotide catabolic processGO:0009261750.034
carbohydrate derivative metabolic processGO:19011351410.033
behaviorGO:00076105270.033
microtubule based processGO:00070171820.032
dna repairGO:0006281230.032
regulation of cell morphogenesisGO:0022604400.032
digestive tract morphogenesisGO:0048546760.032
dna duplex unwindingGO:003250830.032
multi organism behaviorGO:00517053890.032
regulation of meiosisGO:0040020940.032
macromolecular complex assemblyGO:00650031930.032
regulation of localizationGO:00328791940.032
negative regulation of cellular metabolic processGO:0031324950.032
dna metabolic processGO:0006259740.032
ovipositionGO:00189913640.031
phagocytosis engulfmentGO:0006911980.031
actomyosin structure organizationGO:00310321540.031
purine ribonucleotide catabolic processGO:0009154750.031
organonitrogen compound metabolic processGO:19015641510.031
sister chromatid biorientationGO:003113420.030
spindle localizationGO:0051653510.030
negative regulation of post embryonic developmentGO:00485812080.030
regulation of locomotionGO:00400121610.030
male gamete generationGO:0048232410.030
cellular protein complex assemblyGO:00436231780.030
regulation of cell cycle phase transitionGO:1901987130.030
mitotic chromosome condensationGO:000707630.029
ribonucleoside metabolic processGO:0009119980.029
canonical wnt signaling pathwayGO:006007030.029
cellular component assembly involved in morphogenesisGO:00109271830.029
negative regulation of mitotic cell cycleGO:0045930420.029
glycosyl compound metabolic processGO:19016571000.028
regulation of cell differentiationGO:0045595810.028
membrane invaginationGO:0010324980.027
regulation of gtp catabolic processGO:0033124320.027
muscle cell developmentGO:00550011580.027
protein complex assemblyGO:00064611860.027
cell type specific apoptotic processGO:009728540.027
cellular response to inorganic substanceGO:007124130.027
mitotic g2 m transition checkpointGO:004481810.027
gtp catabolic processGO:0006184460.026
single fertilizationGO:0007338610.026
regulation of multicellular organism growthGO:00400143730.026
positive regulation of multicellular organism growthGO:00400183520.025
cellular macromolecule localizationGO:0070727750.025
nucleoside catabolic processGO:0009164780.025
modification dependent macromolecule catabolic processGO:0043632320.025
cellular response to chemical stimulusGO:00708871290.025
regulation of phosphate metabolic processGO:0019220810.024
multicellular organism growthGO:00352643850.024
regulation of cellular protein metabolic processGO:0032268750.024
cellular response to organic substanceGO:00713101190.024
regulation of cell motilityGO:2000145570.023
small gtpase mediated signal transductionGO:0007264320.023
engulfment of apoptotic cellGO:0043652940.023
positive regulation of nematode larval developmentGO:0061063540.023
negative regulation of cell cycleGO:0045786530.023
reciprocal meiotic recombinationGO:0007131110.023
regulation of gene expression epigeneticGO:00400291630.023
guanosine containing compound metabolic processGO:1901068490.023
mitotic cell cycle phase transitionGO:0044772130.022
response to organic substanceGO:00100331310.022
dna geometric changeGO:003239230.022
nucleotide catabolic processGO:0009166770.022
ion transportGO:00068111130.022
cellular macromolecule biosynthetic processGO:00346452470.022
phagocytosisGO:00069091150.022
muscle structure developmentGO:00610611910.022
spermatogenesisGO:0007283410.021
regulation of small gtpase mediated signal transductionGO:0051056410.021
kinetochore assemblyGO:005138250.021
regulation of meiotic cell cycleGO:00514451360.021
regulation of nuclear divisionGO:00517831150.021
reproductive behaviorGO:00190983870.020
negative regulation of signal transductionGO:0009968600.020
regulation of nucleoside metabolic processGO:0009118370.020
gene silencing by rnaGO:00310471430.020
rna interferenceGO:00162461370.020
regulation of nucleotide metabolic processGO:0006140370.019
negative regulation of signalingGO:0023057610.019
regulation of anatomical structure morphogenesisGO:0022603510.019
negative regulation of cell communicationGO:0010648610.019
transmembrane transportGO:00550851100.019
protein transportGO:0015031450.019
positive regulation of molecular functionGO:0044093610.019
glycosyl compound catabolic processGO:1901658790.018
purine ribonucleoside triphosphate catabolic processGO:0009207720.018
apoptotic cell clearanceGO:00432771110.018
embryonic morphogenesisGO:00485981520.018
positive regulation of chromosome organizationGO:200125220.018
single organism biosynthetic processGO:0044711910.018
positive regulation of cell developmentGO:001072060.018
gtp metabolic processGO:0046039460.018
single organism cellular localizationGO:1902580720.017
myofibril assemblyGO:00302391540.017
positive regulation of signalingGO:0023056660.017
posttranscriptional gene silencingGO:00164411430.017
regulation of catalytic activityGO:0050790780.017
regulation of apoptotic processGO:0042981360.017
g1 s transition of mitotic cell cycleGO:000008220.016
regulation of cellular component movementGO:0051270620.016
positive regulation of multicellular organismal processGO:00512404170.016
regulation of apoptotic signaling pathwayGO:200123310.016
response to woundingGO:000961140.016
cuticle developmentGO:00423351000.016
meiosis iGO:0007127190.016
regulation of cell morphogenesis involved in differentiationGO:0010769290.016
protein catabolic processGO:00301631620.016
polar body extrusion after meiotic divisionsGO:0040038140.016
regulation of cell projection organizationGO:0031344380.016
cellular macromolecule catabolic processGO:0044265730.016
system processGO:00030081360.015
regulation of gtpase activityGO:0043087300.015
negative regulation of nitrogen compound metabolic processGO:0051172630.015
secretionGO:00469031470.015
regenerationGO:003109940.015
anatomical structure homeostasisGO:0060249110.015
positive regulation of cell cycleGO:0045787550.015
negative regulation of macromolecule metabolic processGO:00106052290.015
gastrulationGO:0007369580.014
proteolysisGO:0006508610.014
multi organism reproductive behaviorGO:00447053870.014
multi multicellular organism processGO:00447063900.014
organic substance transportGO:00717021130.014
nuclear migrationGO:0007097540.014
regulation of ras protein signal transductionGO:0046578410.014
tissue morphogenesisGO:0048729650.014
nucleus organizationGO:0006997380.013
purine ribonucleoside monophosphate metabolic processGO:0009167430.013
positive regulation of cell morphogenesis involved in differentiationGO:001077040.013
phosphorylationGO:00163101160.013
single organism behaviorGO:0044708830.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.013
positive regulation of programmed cell deathGO:0043068270.013
molting cycle collagen and cuticulin based cuticleGO:00189962810.013
mitotic metaphase plate congressionGO:000708050.013
regulation of stem cell differentiationGO:200073610.013
negative regulation of cellular biosynthetic processGO:0031327650.013
chromatin remodelingGO:000633820.012
regulation of nervous system developmentGO:0051960410.012
muscle cell differentiationGO:00426921710.012
positive regulation of phosphorus metabolic processGO:0010562560.012
regulation of wnt signaling pathwayGO:003011190.012
regulation of sequence specific dna binding transcription factor activityGO:005109030.012
striated muscle myosin thick filament assemblyGO:00716881380.012
somatic muscle developmentGO:000752510.012
dna topological changeGO:000626510.012
cell cycle g1 s phase transitionGO:004484320.012
regulation of cell migrationGO:0030334550.012
negative regulation of macromolecule biosynthetic processGO:0010558650.012
protein oligomerizationGO:005125940.012
regulation of programmed cell deathGO:0043067500.012
positive regulation of stem cell differentiationGO:200073810.012
regulation of neuron differentiationGO:0045664400.012
positive regulation of gtp catabolic processGO:0033126280.012
negative regulation of rna biosynthetic processGO:1902679530.011
regulation of molecular functionGO:0065009890.011
internal peptidyl lysine acetylationGO:001839330.011
microtubule anchoringGO:003445380.011
ubiquitin dependent protein catabolic processGO:0006511320.011
apical junction assemblyGO:004329710.011
embryonic pattern specificationGO:0009880210.011
protein phosphorylationGO:0006468850.011
collagen and cuticulin based cuticle developmentGO:0040002990.011
microtubule cytoskeleton organization involved in mitosisGO:1902850120.011
molting cycleGO:00423032810.011
regulation of chromosome organizationGO:0033044200.011
positive regulation of cellular component organizationGO:0051130340.010
myosin filament assemblyGO:00310341380.010
actin filament based movementGO:003004840.010
epithelial tube morphogenesisGO:006056210.010
negative regulation of neuron differentiationGO:004566540.010
striated muscle cell developmentGO:00550021570.010
positive regulation of purine nucleotide catabolic processGO:0033123280.010
establishment of spindle localizationGO:0051293510.010
neurological system processGO:0050877530.010
regulation of cellular response to oxidative stressGO:190040710.010
male sex differentiationGO:0046661860.010
regulation of epithelial cell differentiationGO:003085640.010
regulation of phosphorus metabolic processGO:0051174810.010
regulation of cell developmentGO:0060284490.010
posttranscriptional gene silencing by rnaGO:00351941430.010
peptidyl amino acid modificationGO:0018193580.010
mrna metabolic processGO:0016071310.010

mel-28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.031
disease of anatomical entityDOID:700.020
cancerDOID:16200.015
organ system cancerDOID:005068600.015
gastrointestinal system cancerDOID:311900.011