Caenorhabditis elegans

10 known processes

lfi-1 (CELE_ZC8.4)

Protein LFI-1

lfi-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.490
post embryonic developmentGO:000979121520.469
locomotionGO:004001116340.360
regulation of developmental processGO:00507936840.352
carbohydrate derivative catabolic processGO:1901136820.327
gene expressionGO:00104674120.284
purine containing compound catabolic processGO:0072523750.263
catabolic processGO:00090563180.260
endocytosisGO:00068978190.236
ribonucleotide catabolic processGO:0009261750.229
aromatic compound catabolic processGO:00194391160.225
establishment of localizationGO:005123411710.216
purine nucleoside triphosphate catabolic processGO:0009146720.205
molting cycle collagen and cuticulin based cuticleGO:00189962810.200
transportGO:000681010930.199
nucleobase containing compound catabolic processGO:00346551140.199
embryo development ending in birth or egg hatchingGO:000979229920.192
cellular nitrogen compound catabolic processGO:00442701190.191
regulation of multicellular organismal processGO:00512397260.191
organ developmentGO:004851311020.186
ribonucleoside metabolic processGO:0009119980.182
nucleoside triphosphate metabolic processGO:0009141870.178
single organism signalingGO:00447004010.172
single organism localizationGO:19025785180.172
organonitrogen compound catabolic processGO:1901565900.171
purine ribonucleotide catabolic processGO:0009154750.162
heterocycle catabolic processGO:00467001190.162
nucleoside catabolic processGO:0009164780.160
organophosphate catabolic processGO:0046434810.160
multicellular organismal agingGO:00102598120.159
nucleoside phosphate catabolic processGO:1901292770.152
purine ribonucleoside catabolic processGO:0046130750.152
purine nucleoside catabolic processGO:0006152750.147
nucleoside triphosphate catabolic processGO:0009143720.146
ribonucleoside triphosphate metabolic processGO:0009199870.145
regulation of biological qualityGO:00650087410.141
multicellular organismal reproductive processGO:00486098150.139
determination of adult lifespanGO:00083408120.136
agingGO:00075688120.136
purine ribonucleoside triphosphate catabolic processGO:0009207720.135
organic substance catabolic processGO:19015752940.135
nucleobase containing compound metabolic processGO:00061394060.132
regulation of response to stimulusGO:00485832430.131
cellular catabolic processGO:00442481990.127
vesicle mediated transportGO:00161928520.119
axon developmentGO:00615641630.118
purine nucleotide catabolic processGO:0006195750.118
atp metabolic processGO:0046034420.116
cell surface receptor signaling pathwayGO:00071661490.115
nucleoside metabolic processGO:0009116990.111
single organism transportGO:00447654470.111
phosphate containing compound metabolic processGO:00067962320.110
post embryonic organ developmentGO:00485693360.110
organic cyclic compound catabolic processGO:19013611190.109
glycosyl compound metabolic processGO:19016571000.109
developmental growthGO:00485894120.106
cellular nitrogen compound biosynthetic processGO:00442711920.105
growthGO:00400075620.104
ribonucleoside catabolic processGO:0042454770.104
head developmentGO:006032210.104
purine nucleoside metabolic processGO:0042278920.101
single organism catabolic processGO:00447121290.100
positive regulation of multicellular organismal processGO:00512404170.100
positive regulation of growthGO:00459273690.098
purine nucleotide metabolic processGO:0006163950.097
localization of cellGO:00516743130.097
signalingGO:00230524010.096
macromolecule localizationGO:00330367710.094
cell developmentGO:00484686960.091
ribonucleoside monophosphate metabolic processGO:0009161450.090
protein metabolic processGO:00195384220.090
cellular component assemblyGO:00226072930.089
negative regulation of biological processGO:00485195670.089
heterocycle biosynthetic processGO:00181301870.089
glycosyl compound catabolic processGO:1901658790.087
skeletal muscle organ developmentGO:006053830.085
nervous system developmentGO:00073992530.084
purine ribonucleoside triphosphate metabolic processGO:0009205870.083
regulation of cellular biosynthetic processGO:00313261890.082
cellular component movementGO:00069283880.080
phosphorus metabolic processGO:00067932320.080
cell projection organizationGO:00300302310.080
purine nucleoside triphosphate metabolic processGO:0009144870.079
organonitrogen compound metabolic processGO:19015641510.078
metal ion transportGO:0030001490.076
body morphogenesisGO:00101716200.075
carbohydrate derivative metabolic processGO:19011351410.075
purine ribonucleoside metabolic processGO:0046128920.075
generation of neuronsGO:00486992350.074
single organism reproductive processGO:004470211960.074
cellular biosynthetic processGO:00442493150.072
neuron differentiationGO:00301822170.072
transmembrane transportGO:00550851100.072
regulation of developmental growthGO:00486383890.071
sexual reproductionGO:00199535460.071
multicellular organism growthGO:00352643850.070
maintenance of locationGO:00512355800.069
nucleotide catabolic processGO:0009166770.069
multicellular organism reproductionGO:00325048190.069
ribonucleoside triphosphate catabolic processGO:0009203720.067
regulation of macromolecule metabolic processGO:00602554210.067
positive regulation of developmental growthGO:00486393540.067
lipid localizationGO:00108765730.065
ribonucleotide metabolic processGO:0009259990.065
molting cycleGO:00423032810.065
cellular component morphogenesisGO:00329893180.064
macromolecule biosynthetic processGO:00090592500.063
multi organism reproductive processGO:00447038670.063
regulation of nucleobase containing compound metabolic processGO:00192192220.062
developmental process involved in reproductionGO:000300611650.062
ion transportGO:00068111130.062
positive regulation of multicellular organism growthGO:00400183520.061
ion transmembrane transportGO:0034220910.061
cellular component biogenesisGO:00440852970.061
lipid storageGO:00199155650.061
organic substance biosynthetic processGO:19015763230.059
ribose phosphate metabolic processGO:0019693990.057
regulation of multicellular organismal developmentGO:20000263170.057
regulation of catalytic activityGO:0050790780.056
cellular protein metabolic processGO:00442672790.055
regulation of cellular component organizationGO:00511282480.053
regulation of transcription dna templatedGO:00063551640.053
small molecule metabolic processGO:00442811860.053
regulation of multicellular organism growthGO:00400143730.052
protein modification processGO:00362112070.051
genitalia developmentGO:00488067410.051
regulation of growthGO:00400084090.050
regulation of catabolic processGO:0009894570.050
signal transductionGO:00071653170.050
nucleoside phosphate metabolic processGO:00067531080.049
regulation of gene expressionGO:00104683660.049
regulation of metabolic processGO:00192224780.049
response to chemicalGO:00422213560.049
neuron projection developmentGO:00311751870.048
macromolecular complex subunit organizationGO:00439333200.048
organelle organizationGO:00069967830.048
cellular macromolecule biosynthetic processGO:00346452470.046
gonad developmentGO:00084068400.046
regulation of nitrogen compound metabolic processGO:00511712220.046
gamete generationGO:00072764610.045
intracellular signal transductionGO:0035556960.045
cell deathGO:00082195470.045
cellular component assembly involved in morphogenesisGO:00109271830.045
nucleic acid templated transcriptionGO:00976591690.045
biosynthetic processGO:00090583230.044
female gamete generationGO:00072922540.043
digestive tract developmentGO:00485651220.043
regulation of localizationGO:00328791940.043
ovipositionGO:00189913640.042
response to external stimulusGO:00096052890.042
receptor mediated endocytosisGO:00068987150.042
nucleotide metabolic processGO:00091171080.042
cellular macromolecular complex assemblyGO:00346221840.041
anatomical structure homeostasisGO:0060249110.040
purine ribonucleoside monophosphate metabolic processGO:0009167430.039
protein complex subunit organizationGO:00718222800.039
negative regulation of cellular processGO:00485232390.039
purine ribonucleotide metabolic processGO:0009150950.039
neurogenesisGO:00220082360.039
mitotic nuclear divisionGO:0007067890.039
regulation of primary metabolic processGO:00800902920.038
epithelial tube morphogenesisGO:006056210.038
macromolecule catabolic processGO:00090572020.038
aromatic compound biosynthetic processGO:00194381920.038
apoptotic processGO:00069154780.037
hermaphrodite genitalia developmentGO:00400357340.037
organelle assemblyGO:00709252140.037
negative regulation of metabolic processGO:00098922400.037
system processGO:00030081360.037
reproductive system developmentGO:00614588500.037
atp catabolic processGO:0006200270.037
reproductive structure developmentGO:00486088500.037
cellular localizationGO:00516413600.037
inorganic ion transmembrane transportGO:0098660540.036
regulation of biosynthetic processGO:00098891890.036
negative regulation of gene expressionGO:00106292170.036
positive regulation of catabolic processGO:0009896380.036
cell migrationGO:00164773060.036
negative regulation of multicellular organismal processGO:00512412360.036
regulation of cellular metabolic processGO:00313233050.036
regulation of nucleic acid templated transcriptionGO:19035061650.036
organic cyclic compound biosynthetic processGO:19013621950.035
regulation of purine nucleotide catabolic processGO:0033121350.035
negative regulation of developmental processGO:00510932270.035
negative regulation of gene expression epigeneticGO:004581420.035
sex differentiationGO:00075489090.035
positive regulation of cellular metabolic processGO:00313251780.034
multi organism reproductive behaviorGO:00447053870.034
establishment of localization in cellGO:00516493180.034
positive regulation of molecular functionGO:0044093610.034
rna biosynthetic processGO:00327741690.033
positive regulation of nucleoside metabolic processGO:0045979280.033
positive regulation of developmental processGO:00510944080.033
regulation of cellular macromolecule biosynthetic processGO:20001121880.032
rho protein signal transductionGO:000726620.032
behaviorGO:00076105270.032
programmed cell deathGO:00125015000.032
negative regulation of macromolecule metabolic processGO:00106052290.031
purine ribonucleoside monophosphate catabolic processGO:0009169280.031
multicellular organismal reproductive behaviorGO:00330573840.031
cellular protein modification processGO:00064642070.031
macromolecular complex assemblyGO:00650031930.030
nucleoside monophosphate metabolic processGO:0009123460.030
g protein coupled receptor signaling pathwayGO:0007186460.030
regulation of phosphorus metabolic processGO:0051174810.030
purine containing compound metabolic processGO:0072521950.029
regulation of nucleotide metabolic processGO:0006140370.029
purine nucleoside monophosphate catabolic processGO:0009128280.029
organophosphate metabolic processGO:00196371250.029
protein complex assemblyGO:00064611860.029
cell morphogenesis involved in neuron differentiationGO:00486671110.029
response to acid chemicalGO:000110140.029
multi multicellular organism processGO:00447063900.029
ras protein signal transductionGO:0007265310.029
fertilizationGO:0009566630.028
regulation of cellular catabolic processGO:0031329510.028
regulation of nucleoside metabolic processGO:0009118370.028
chromosome segregationGO:00070591800.028
regulation of macromolecule biosynthetic processGO:00105561890.028
regulation of molecular functionGO:0065009890.028
regulation of cell communicationGO:00106461760.028
meiotic cell cycleGO:00513213350.028
uterus morphogenesisGO:006103820.028
cell cell signalingGO:00072671180.028
rna metabolic processGO:00160702280.027
cytoskeleton organizationGO:00070103390.027
cation transportGO:0006812780.027
organ morphogenesisGO:0009887670.027
macromolecule modificationGO:00434122180.027
myofibril assemblyGO:00302391540.027
myosin filament assemblyGO:00310341380.026
cell motilityGO:00488703130.026
protein complex biogenesisGO:00702711860.026
reproductive behaviorGO:00190983870.026
taxisGO:00423301280.026
cuticle developmentGO:00423351000.025
axon guidanceGO:0007411820.025
myosin filament organizationGO:00310331380.025
cellular response to nitrogen compoundGO:1901699240.025
muscle tissue developmentGO:006053710.025
nucleobase containing compound biosynthetic processGO:00346541840.025
cytokinesisGO:0000910800.025
inductive cell migrationGO:00400391450.025
small gtpase mediated signal transductionGO:0007264320.025
gene silencingGO:00164581430.025
multi organism behaviorGO:00517053890.025
positive regulation of nucleotide catabolic processGO:0030813280.025
posttranscriptional regulation of gene expressionGO:00106081660.025
regulation of rna biosynthetic processGO:20011411650.024
actomyosin structure organizationGO:00310321540.024
establishment of organelle localizationGO:00516561230.024
regulation of signalingGO:00230511720.024
regulation of anatomical structure sizeGO:0090066460.024
tube developmentGO:00352951260.024
neuron projection guidanceGO:0097485820.023
positive regulation of cellular processGO:00485223320.023
regulation of gene expression epigeneticGO:00400291630.023
collagen and cuticulin based cuticle developmentGO:0040002990.023
development of primary sexual characteristicsGO:00451378400.023
organelle localizationGO:00516401270.023
nucleic acid metabolic processGO:00903042990.023
protein catabolic processGO:00301631620.023
regulation of cell projection organizationGO:0031344380.023
organelle fissionGO:00482853630.022
regulation of signal transductionGO:00099661350.022
neuron developmentGO:00486661990.022
cell part morphogenesisGO:00329901520.021
regulation of system processGO:0044057270.021
anatomical structure formation involved in morphogenesisGO:00486462500.021
regulation of nucleotide catabolic processGO:0030811350.021
axonogenesisGO:00074091020.021
tissue developmentGO:00098881120.021
positive regulation of cellular catabolic processGO:0031331350.020
cellular protein complex assemblyGO:00436231780.020
nucleobase containing small molecule metabolic processGO:00550861150.020
cell projection morphogenesisGO:00488581480.019
protein oligomerizationGO:005125940.019
regulation of phosphate metabolic processGO:0019220810.019
muscle system processGO:0003012430.019
response to woundingGO:000961140.019
striated muscle myosin thick filament assemblyGO:00716881380.019
mitotic cell cycle processGO:19030471940.019
actin cytoskeleton organizationGO:00300361840.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of locomotionGO:00400121610.018
striated muscle cell developmentGO:00550021570.018
response to abiotic stimulusGO:00096281520.018
defense response to other organismGO:00985421000.018
actin filament based movementGO:003004840.018
positive regulation of catalytic activityGO:0043085590.018
neuromuscular junction developmentGO:000752820.018
regulation of apoptotic signaling pathwayGO:200123310.018
establishment of nucleus localizationGO:0040023550.018
negative regulation of cellular metabolic processGO:0031324950.018
extracellular matrix organizationGO:003019860.018
dna metabolic processGO:0006259740.018
transcription dna templatedGO:00063511680.018
regulation of response to woundingGO:190303410.017
nuclear migrationGO:0007097540.017
negative regulation of response to stimulusGO:0048585730.017
positive regulation of purine nucleotide catabolic processGO:0033123280.017
cell projection assemblyGO:0030031350.017
posttranscriptional gene silencing by rnaGO:00351941430.017
chemotaxisGO:00069351200.017
guanosine containing compound metabolic processGO:1901068490.017
negative regulation of signalingGO:0023057610.017
regulation of transportGO:0051049910.017
protein phosphorylationGO:0006468850.017
regulation of behaviorGO:0050795970.017
muscle attachmentGO:001620330.017
positive regulation of metabolic processGO:00098931870.017
regulation of ras gtpase activityGO:0032318210.016
adult behaviorGO:003053430.016
deathGO:00162655470.016
cytosolic calcium ion homeostasisGO:005148020.016
secretionGO:00469031470.016
neurological system processGO:0050877530.016
cell cycle processGO:00224024820.016
muscle cell developmentGO:00550011580.016
actin filament based processGO:00300291910.016
cellular process involved in reproduction in multicellular organismGO:00224123510.016
neuromuscular processGO:005090510.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.016
positive regulation of gtpase activityGO:0043547280.015
eating behaviorGO:0042755590.015
regulation of protein localizationGO:0032880500.015
regulation of gtp catabolic processGO:0033124320.015
secretion by cellGO:00329401380.015
cell morphogenesisGO:00009021630.015
peptidyl serine phosphorylationGO:0018105200.015
vulval developmentGO:00400253330.015
memoryGO:000761330.015
posttranscriptional gene silencingGO:00164411430.015
organic substance transportGO:00717021130.015
oogenesisGO:00484772290.014
intracellular transportGO:0046907770.014
cellular amine metabolic processGO:0044106150.014
rna localizationGO:000640330.014
regulation of cellular amine metabolic processGO:003323800.014
negative regulation of neurogenesisGO:005076840.014
microtubule based movementGO:0007018330.014
regulation of cellular component sizeGO:0032535400.014
regulation of cellular protein metabolic processGO:0032268750.014
positive regulation of nitrogen compound metabolic processGO:00511731340.014
regulation of gtpase activityGO:0043087300.014
calcium mediated signalingGO:001972230.014
meiotic nuclear divisionGO:00071263000.014
actin cytoskeleton reorganizationGO:003153240.014
positive regulation of gtp catabolic processGO:0033126280.014
regulation of muscle system processGO:0090257200.014
rna interferenceGO:00162461370.014
protein localizationGO:00081042050.014
regulation of cellular ketone metabolic processGO:001056530.014
regulation of post embryonic developmentGO:00485802600.014
basement membrane organizationGO:007171130.014
cell recognitionGO:0008037850.014
regulation of cell developmentGO:0060284490.014
neuron recognitionGO:0008038830.013
response to mechanical stimulusGO:0009612280.013
negative regulation of neuron differentiationGO:004566540.013
negative regulation of nitrogen compound metabolic processGO:0051172630.013
synaptic growth at neuromuscular junctionGO:005112410.013
regulation of cytoplasmic transportGO:190364930.013
chromatin remodelingGO:000633820.013
ribonucleoprotein complex assemblyGO:002261840.013
response to topologically incorrect proteinGO:0035966820.013
regulation of rna metabolic processGO:00512521730.013
muscle contractionGO:0006936430.013
regulation of lipid metabolic processGO:001921640.013
nucleus localizationGO:0051647550.013
cell type specific apoptotic processGO:009728540.013
establishment of protein localization to membraneGO:009015030.013
anion transportGO:0006820300.013
guanosine containing compound catabolic processGO:1901069480.013
cellular ketone metabolic processGO:0042180140.013
positive regulation of phosphate metabolic processGO:0045937560.012
oxoacid metabolic processGO:0043436470.012
carboxylic acid metabolic processGO:0019752340.012
regulation of cell cycleGO:00517261940.012
regulation of ras protein signal transductionGO:0046578410.012
positive regulation of neuron projection developmentGO:001097640.012
bmp signaling pathwayGO:003050930.012
axonal fasciculationGO:0007413790.012
gtp catabolic processGO:0006184460.012
monovalent inorganic cation transportGO:0015672330.012
negative regulation of response to external stimulusGO:003210230.012
ribonucleoside monophosphate catabolic processGO:0009158280.012
regulation of hydrolase activityGO:0051336450.012
positive regulation of phosphorus metabolic processGO:0010562560.012
positive regulation of macromolecule metabolic processGO:00106041490.012
muscle cell differentiationGO:00426921710.012
purine nucleoside monophosphate metabolic processGO:0009126430.012
locomotory behaviorGO:0007626400.012
cellular amino acid metabolic processGO:0006520150.012
positive regulation of protein transportGO:005122240.012
cation transmembrane transportGO:0098655590.012
positive regulation of purine nucleotide metabolic processGO:1900544280.011
negative regulation of nematode larval developmentGO:00610642080.011
response to inorganic substanceGO:0010035500.011
maintenance of location in cellGO:0051651120.011
somatic muscle developmentGO:000752510.011
negative regulation of signal transductionGO:0009968600.011
gene silencing by rnaGO:00310471430.011
negative regulation of cellular component organizationGO:0051129330.011
cell divisionGO:00513012620.011
peptidyl serine modificationGO:0018209200.011
nuclear envelope reassemblyGO:003146840.011
detection of external stimulusGO:000958140.011
carboxylic acid transportGO:0046942150.011
positive regulation of secretion by cellGO:1903532140.011
sensory organ morphogenesisGO:009059620.011
regulation of g protein coupled receptor protein signaling pathwayGO:000827740.011
transcription from rna polymerase ii promoterGO:00063661490.011
cell adhesionGO:0007155210.011
response to oxygen containing compoundGO:1901700440.011
cation homeostasisGO:0055080200.011
membrane organizationGO:00610241350.011
gastrulationGO:0007369580.011
cellular macromolecule localizationGO:0070727750.010
apoptotic cell clearanceGO:00432771110.010
regulation of calcium ion transportGO:005192430.010
chromatin assembly or disassemblyGO:000633310.010
filopodium assemblyGO:004684720.010
positive regulation of cell morphogenesis involved in differentiationGO:001077040.010
muscle fiber developmentGO:004874720.010
adult locomotory behaviorGO:000834410.010
phagocytosis engulfmentGO:0006911980.010
insulin receptor signaling pathwayGO:0008286140.010
nucleoside monophosphate catabolic processGO:0009125280.010
tube morphogenesisGO:0035239790.010

lfi-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.062
congenital muscular dystrophyDOID:005055700.035
muscular diseaseDOID:008000000.035
muscular dystrophyDOID:988400.035
muscle tissue diseaseDOID:6600.035
musculoskeletal system diseaseDOID:1700.035
myopathyDOID:42300.035
nervous system diseaseDOID:86300.029
cardiovascular system diseaseDOID:128700.025
intrinsic cardiomyopathyDOID:006003600.025
heart diseaseDOID:11400.025
cardiomyopathyDOID:005070000.025
dilated cardiomyopathyDOID:1293000.025
emery dreifuss muscular dystrophyDOID:1172600.011