Caenorhabditis elegans

117 known processes

sem-4 (CELE_F15C11.1)

Protein SEM-4

sem-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signalingGO:00230524010.688
Zebrafish Mouse
transportGO:000681010930.631
post embryonic developmentGO:000979121520.555
single organism reproductive processGO:004470211960.553
establishment of localizationGO:005123411710.528
single organism signalingGO:00447004010.496
Zebrafish Mouse
embryo developmentGO:000979030520.466
embryo development ending in birth or egg hatchingGO:000979229920.400
Mouse
locomotionGO:004001116340.370
tube developmentGO:00352951260.370
vesicle mediated transportGO:00161928520.353
anatomical structure formation involved in morphogenesisGO:00486462500.321
sex differentiationGO:00075489090.316
single organism transportGO:00447654470.304
reproductive system developmentGO:00614588500.278
organelle localizationGO:00516401270.277
development of primary sexual characteristicsGO:00451378400.276
behaviorGO:00076105270.267
cell fate commitmentGO:00451651390.266
Mouse
single organism localizationGO:19025785180.264
cell migrationGO:00164773060.256
body morphogenesisGO:00101716200.253
regulation of multicellular organismal processGO:00512397260.243
Mouse
sexual reproductionGO:00199535460.238
developmental process involved in reproductionGO:000300611650.226
digestive tract developmentGO:00485651220.223
multicellular organismal reproductive processGO:00486098150.222
positive regulation of multicellular organismal processGO:00512404170.216
Mouse
nervous system developmentGO:00073992530.201
macromolecule localizationGO:00330367710.201
positive regulation of rna biosynthetic processGO:19026801020.196
Mouse
regulation of developmental processGO:00507936840.194
Mouse
cytoskeleton organizationGO:00070103390.193
positive regulation of developmental processGO:00510944080.187
Mouse
aromatic compound biosynthetic processGO:00194381920.185
signal transductionGO:00071653170.173
Zebrafish Mouse
digestive tract morphogenesisGO:0048546760.167
multicellular organism reproductionGO:00325048190.158
reproductive structure developmentGO:00486088500.156
regulation of cell communicationGO:00106461760.150
Zebrafish Mouse
cell developmentGO:00484686960.149
Mouse
regulation of biological qualityGO:00650087410.149
system processGO:00030081360.147
regulation of growthGO:00400084090.142
negative regulation of gene expressionGO:00106292170.142
regulation of cell morphogenesis involved in differentiationGO:0010769290.141
Mouse
membrane organizationGO:00610241350.138
regulation of signalingGO:00230511720.134
Zebrafish Mouse
genitalia developmentGO:00488067410.133
multi organism behaviorGO:00517053890.128
cell motilityGO:00488703130.128
positive regulation of nucleic acid templated transcriptionGO:19035081020.128
Mouse
cell divisionGO:00513012620.127
organelle organizationGO:00069967830.127
Mouse
establishment of organelle localizationGO:00516561230.127
gonad developmentGO:00084068400.121
hermaphrodite genitalia developmentGO:00400357340.120
ovipositionGO:00189913640.118
cellular macromolecular complex assemblyGO:00346221840.118
regulation of multicellular organismal developmentGO:20000263170.118
Mouse
multi organism reproductive behaviorGO:00447053870.117
positive regulation of cell communicationGO:0010647690.117
Zebrafish
embryonic morphogenesisGO:00485981520.116
response to chemicalGO:00422213560.115
Zebrafish
regulation of cell differentiationGO:0045595810.114
Mouse
cellular protein complex assemblyGO:00436231780.112
cell deathGO:00082195470.112
positive regulation of developmental growthGO:00486393540.110
endocytosisGO:00068978190.109
regulation of nematode larval developmentGO:00610622600.109
multicellular organism growthGO:00352643850.108
positive regulation of cell projection organizationGO:003134640.108
localization of cellGO:00516743130.107
post embryonic organ developmentGO:00485693360.103
agingGO:00075688120.101
developmental growthGO:00485894120.101
Mouse
cellular component movementGO:00069283880.100
multi organism reproductive processGO:00447038670.099
tube morphogenesisGO:0035239790.099
organ morphogenesisGO:0009887670.098
Mouse
cell morphogenesisGO:00009021630.098
Mouse
single organism organelle organizationGO:19025895010.097
Mouse
negative regulation of transcription dna templatedGO:0045892530.097
neurogenesisGO:00220082360.095
developmental cell growthGO:0048588390.094
regulation of cell morphogenesisGO:0022604400.094
Mouse
molting cycleGO:00423032810.093
axon developmentGO:00615641630.092
neuron differentiationGO:00301822170.092
Mouse
positive regulation of growthGO:00459273690.091
vulval developmentGO:00400253330.089
protein localizationGO:00081042050.088
multi multicellular organism processGO:00447063900.085
lipid localizationGO:00108765730.085
multicellular organismal agingGO:00102598120.084
single organism cellular localizationGO:1902580720.084
ion transportGO:00068111130.082
regulation of developmental growthGO:00486383890.081
cellular component assemblyGO:00226072930.079
regulation of multicellular organism growthGO:00400143730.079
generation of neuronsGO:00486992350.079
maintenance of locationGO:00512355800.078
gene expressionGO:00104674120.077
developmental growth involved in morphogenesisGO:0060560370.076
Mouse
synaptic transmissionGO:00072681060.075
tissue developmentGO:00098881120.075
lipid storageGO:00199155650.074
negative regulation of macromolecule metabolic processGO:00106052290.074
tissue morphogenesisGO:0048729650.073
regulation of cellular component sizeGO:0032535400.072
positive regulation of macromolecule biosynthetic processGO:00105571090.070
Mouse
mechanosensory behaviorGO:0007638250.070
epithelial tube morphogenesisGO:006056210.068
Mouse
negative regulation of nucleic acid templated transcriptionGO:1903507530.068
response to mechanical stimulusGO:0009612280.067
digestive system developmentGO:00551231220.067
synaptic vesicle recyclingGO:003646530.066
receptor mediated endocytosisGO:00068987150.066
neurological system processGO:0050877530.064
positive regulation of metabolic processGO:00098931870.062
Mouse
negative regulation of metabolic processGO:00098922400.061
cellular localizationGO:00516413600.058
positive regulation of multicellular organism growthGO:00400183520.058
regulation of signal transductionGO:00099661350.058
Zebrafish Mouse
cell cell signalingGO:00072671180.058
Mouse
muscle cell differentiationGO:00426921710.057
ion transmembrane transportGO:0034220910.056
growthGO:00400075620.055
Mouse
regulation of neuron differentiationGO:0045664400.054
Mouse
organelle assemblyGO:00709252140.053
cellular component morphogenesisGO:00329893180.052
Mouse
response to abiotic stimulusGO:00096281520.052
reproductive behaviorGO:00190983870.051
actin cytoskeleton organizationGO:00300361840.051
mesodermal cell fate specificationGO:0007501130.050
regulation of macromolecule metabolic processGO:00602554210.050
neuron projection developmentGO:00311751870.049
cellular component biogenesisGO:00440852970.049
epithelium developmentGO:0060429680.049
Mouse
multicellular organismal reproductive behaviorGO:00330573840.049
regulation of biosynthetic processGO:00098891890.049
mesoderm developmentGO:0007498270.048
cell fate commitment involved in formation of primary germ layerGO:0060795330.048
response to external stimulusGO:00096052890.048
gamete generationGO:00072764610.047
negative regulation of nucleobase containing compound metabolic processGO:0045934630.046
negative regulation of biological processGO:00485195670.046
molting cycle collagen and cuticulin based cuticleGO:00189962810.045
macromolecular complex assemblyGO:00650031930.044
regulation of metabolic processGO:00192224780.043
organ developmentGO:004851311020.042
Mouse
regulation of cellular biosynthetic processGO:00313261890.042
macromolecular complex subunit organizationGO:00439333200.042
Mouse
heterocycle biosynthetic processGO:00181301870.042
cell projection organizationGO:00300302310.042
negative regulation of cellular processGO:00485232390.041
regulation of primary metabolic processGO:00800902920.041
negative regulation of developmental processGO:00510932270.041
Mouse
single organism behaviorGO:0044708830.041
protein complex subunit organizationGO:00718222800.041
neuron developmentGO:00486661990.041
Mouse
regulation of localizationGO:00328791940.039
nucleic acid templated transcriptionGO:00976591690.039
positive regulation of macromolecule metabolic processGO:00106041490.038
Mouse
pattern specification processGO:0007389590.037
cell cycle processGO:00224024820.037
defense responseGO:00069522960.036
positive regulation of cellular biosynthetic processGO:00313281090.036
Mouse
regulation of rna metabolic processGO:00512521730.036
positive regulation of cellular metabolic processGO:00313251780.036
Mouse
protein complex assemblyGO:00064611860.036
cellular process involved in reproduction in multicellular organismGO:00224123510.035
regulation of axonogenesisGO:0050770240.035
regulation of vulval developmentGO:00400282480.035
negative regulation of cell morphogenesis involved in differentiationGO:001077120.035
Mouse
neuron projection extensionGO:1990138370.034
protein complex biogenesisGO:00702711860.034
negative regulation of cellular biosynthetic processGO:0031327650.033
regulation of locomotionGO:00400121610.032
striated muscle cell developmentGO:00550021570.032
regulation of response to stimulusGO:00485832430.032
Zebrafish Mouse
synaptic vesicle localizationGO:0097479220.031
establishment of localization in cellGO:00516493180.031
cell cycleGO:00070495260.031
programmed cell deathGO:00125015000.030
protein metabolic processGO:00195384220.030
Mouse
actin filament based processGO:00300291910.030
nucleobase containing compound metabolic processGO:00061394060.030
positive regulation of gene expressionGO:00106281120.030
Mouse
response to other organismGO:00517071010.030
establishment of cell polarityGO:0030010460.030
regulation of extent of cell growthGO:0061387200.030
deathGO:00162655470.029
cell type specific apoptotic processGO:009728540.029
regulation of cellular component organizationGO:00511282480.029
Mouse
determination of adult lifespanGO:00083408120.029
regulation of anatomical structure morphogenesisGO:0022603510.028
Mouse
response to organic substanceGO:00100331310.027
Zebrafish
rna metabolic processGO:00160702280.027
regulation of rna biosynthetic processGO:20011411650.027
neuron recognitionGO:0008038830.027
positive regulation of cellular processGO:00485223320.027
Zebrafish Mouse
asymmetric protein localizationGO:0008105350.027
apoptotic processGO:00069154780.027
regulation of cell projection organizationGO:0031344380.027
defense response to bacteriumGO:0042742860.027
nucleobase containing compound biosynthetic processGO:00346541840.027
germ cell developmentGO:00072813510.026
negative regulation of macromolecule biosynthetic processGO:0010558650.026
muscle structure developmentGO:00610611910.026
rho protein signal transductionGO:000726620.026
regulation of post embryonic developmentGO:00485802600.026
negative regulation of biosynthetic processGO:0009890650.026
cell growthGO:0016049440.026
macromolecule catabolic processGO:00090572020.026
vesicle localizationGO:0051648240.026
cellular response to abiotic stimulusGO:007121440.025
male sex differentiationGO:0046661860.025
response to biotic stimulusGO:00096071010.025
striated muscle cell differentiationGO:00511461580.025
hormone metabolic processGO:004244530.024
organic substance biosynthetic processGO:19015763230.024
positive regulation of neuron projection developmentGO:001097640.024
positive regulation of rna metabolic processGO:00512541030.024
Mouse
regulation of catalytic activityGO:0050790780.024
transcription from rna polymerase ii promoterGO:00063661490.024
enzyme linked receptor protein signaling pathwayGO:0007167500.023
Zebrafish
negative regulation of nematode larval developmentGO:00610642080.023
transcription dna templatedGO:00063511680.023
positive regulation of catalytic activityGO:0043085590.023
muscle cell developmentGO:00550011580.023
positive regulation of cell morphogenesis involved in differentiationGO:001077040.023
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.022
organic substance catabolic processGO:19015752940.022
dauer larval developmentGO:0040024920.022
positive regulation of epithelial cell proliferationGO:005067910.022
feeding behaviorGO:0007631700.021
cation transportGO:0006812780.021
regulation of gene expression epigeneticGO:00400291630.021
response to endogenous stimulusGO:0009719330.021
Zebrafish
myofibril assemblyGO:00302391540.021
protein catabolic processGO:00301631620.021
establishment of vesicle localizationGO:0051650230.021
establishment of spindle localizationGO:0051293510.021
synaptic vesicle transportGO:0048489210.021
negative regulation of post embryonic developmentGO:00485812080.021
nucleic acid metabolic processGO:00903042990.020
negative regulation of response to stimulusGO:0048585730.020
Mouse
oogenesisGO:00484772290.019
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.019
collagen and cuticulin based cuticle developmentGO:0040002990.019
cellular nitrogen compound biosynthetic processGO:00442711920.019
regulation of cellular metabolic processGO:00313233050.019
phosphate containing compound metabolic processGO:00067962320.019
sensory organ morphogenesisGO:009059620.019
cell part morphogenesisGO:00329901520.019
actomyosin structure organizationGO:00310321540.019
cuticle developmentGO:00423351000.019
negative regulation of multicellular organismal processGO:00512412360.018
Mouse
establishment of nucleus localizationGO:0040023550.018
positive regulation of signal transductionGO:0009967400.018
Zebrafish
regulation of organelle organizationGO:00330431640.018
regulation of cell fate specificationGO:0042659220.018
myosin filament organizationGO:00310331380.018
regulation of apoptotic signaling pathwayGO:200123310.018
negative regulation of rna biosynthetic processGO:1902679530.018
cellular protein localizationGO:0034613750.018
negative regulation of cellular metabolic processGO:0031324950.018
neurotransmitter transportGO:0006836320.018
regulation of intracellular signal transductionGO:1902531770.018
positive regulation of nucleobase containing compound metabolic processGO:00459351340.018
Mouse
intracellular signal transductionGO:0035556960.017
defense response to other organismGO:00985421000.017
response to heatGO:0009408500.017
regulation of nucleobase containing compound metabolic processGO:00192192220.017
positive regulation of neuron differentiationGO:004566640.017
Mouse
neurotransmitter secretionGO:0007269260.017
striated muscle myosin thick filament assemblyGO:00716881380.017
chemosensory behaviorGO:0007635330.017
cellular biosynthetic processGO:00442493150.017
secretion by cellGO:00329401380.017
meiotic cell cycleGO:00513213350.017
negative regulation of rna metabolic processGO:0051253530.017
phosphorus metabolic processGO:00067932320.016
cellular macromolecule localizationGO:0070727750.016
axonal fasciculationGO:0007413790.016
nucleus localizationGO:0051647550.016
response to external biotic stimulusGO:00432071010.016
microtubule based processGO:00070171820.016
nematode male tail tip morphogenesisGO:0045138770.016
regulation of gene expressionGO:00104683660.016
developmental maturationGO:0021700260.015
regulation of behaviorGO:0050795970.015
mitotic cell cycle processGO:19030471940.015
axonogenesisGO:00074091020.015
regulation of neuron projection developmentGO:0010975310.015
regulation of lipid metabolic processGO:001921640.015
rna biosynthetic processGO:00327741690.014
cellular component assembly involved in morphogenesisGO:00109271830.014
negative regulation of nitrogen compound metabolic processGO:0051172630.014
posttranscriptional gene silencing by rnaGO:00351941430.014
cellular response to stressGO:00335541620.014
amine metabolic processGO:0009308150.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.014
Zebrafish
regulation of pharyngeal pumpingGO:0043051360.013
myosin filament assemblyGO:00310341380.013
cell projection morphogenesisGO:00488581480.013
cytokinesisGO:0000910800.013
biosynthetic processGO:00090583230.013
lipid metabolic processGO:0006629770.013
posttranscriptional gene silencingGO:00164411430.013
cellular response to chemical stimulusGO:00708871290.013
Zebrafish
regulation of transcription from rna polymerase ii promoterGO:00063571450.013
establishment of mitotic spindle localizationGO:0040001410.013
hindgut developmentGO:006152530.013
regulation of cell deathGO:0010941650.013
monovalent inorganic cation transportGO:0015672330.013
catabolic processGO:00090563180.013
meiotic cell cycle processGO:19030461700.013
protein modification processGO:00362112070.013
Mouse
negative regulation of axon extensionGO:003051720.013
phagocytosis engulfmentGO:0006911980.013
cellular response to organic substanceGO:00713101190.013
Zebrafish
negative regulation of cell communicationGO:0010648610.012
Mouse
male anatomical structure morphogenesisGO:0090598780.012
taxisGO:00423301280.012
positive regulation of signalingGO:0023056660.012
Zebrafish
muscle tissue developmentGO:006053710.012
organelle fusionGO:004828480.012
mesodermal cell differentiationGO:0048333150.012
cell proliferationGO:00082831160.012
Mouse
regulation of mitotic cell cycleGO:0007346760.012
gene silencingGO:00164581430.012
regulation of axon extensionGO:0030516200.012
negative regulation of axonogenesisGO:005077120.012
gastrulationGO:0007369580.012
regulation of cellular macromolecule biosynthetic processGO:20001121880.012
regulation of nervous system developmentGO:0051960410.012
Mouse
neuroblast divisionGO:005505790.012
cellular protein metabolic processGO:00442672790.012
Mouse
neuromuscular junction developmentGO:000752820.012
signal releaseGO:0023061280.012
organic substance transportGO:00717021130.011
sensory perception of tasteGO:005090940.011
asymmetric cell divisionGO:0008356360.011
response to woundingGO:000961140.011
positive regulation of nitrogen compound metabolic processGO:00511731340.011
Mouse
hormone transportGO:000991420.011
regulation of multi organism processGO:0043900690.011
positive regulation of protein kinase activityGO:0045860180.011
small molecule metabolic processGO:00442811860.011
regulation of cell cycleGO:00517261940.011
asymmetric protein localization involved in cell fate determinationGO:0045167180.011
positive regulation of phosphorus metabolic processGO:0010562560.011
regulation of epithelial cell proliferationGO:005067810.011
organelle fissionGO:00482853630.011
apical junction assemblyGO:004329710.011
intraspecies interaction between organismsGO:005170330.011
establishment of synaptic vesicle localizationGO:0097480210.011
matingGO:0007618340.011
positive regulation of neurotransmitter transportGO:0051590110.011
negative regulation of cellular component organizationGO:0051129330.010
Mouse
synaptic vesicle endocytosisGO:004848830.010
apoptotic cell clearanceGO:00432771110.010
regulation of cellular amine metabolic processGO:003323800.010
striated muscle contractionGO:0006941170.010
synaptic vesicle primingGO:001608220.010
excretionGO:0007588490.010
regulation of hormone secretionGO:004688320.010

sem-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
cancerDOID:16200.013
gastrointestinal system cancerDOID:311900.013
large intestine cancerDOID:567200.013
intestinal cancerDOID:1015500.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
inherited metabolic disorderDOID:65500.011
carbohydrate metabolic disorderDOID:297800.011
disease of metabolismDOID:001466700.011