Caenorhabditis elegans

131 known processes

lin-1 (CELE_C37F5.1)

Protein LIN-1

lin-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular processGO:00485223320.439
Human Mouse
positive regulation of nucleic acid templated transcriptionGO:19035081020.381
Human Mouse
organic cyclic compound biosynthetic processGO:19013621950.378
regulation of transcription from rna polymerase ii promoterGO:00063571450.356
positive regulation of cellular metabolic processGO:00313251780.344
Human Mouse
rna biosynthetic processGO:00327741690.341
regulation of primary metabolic processGO:00800902920.340
cell fate commitmentGO:00451651390.339
organ developmentGO:004851311020.335
positive regulation of metabolic processGO:00098931870.326
Human Mouse
regulation of cellular metabolic processGO:00313233050.322
regulation of macromolecule metabolic processGO:00602554210.316
positive regulation of macromolecule metabolic processGO:00106041490.309
Human Mouse
post embryonic developmentGO:000979121520.295
cellular biosynthetic processGO:00442493150.277
hermaphrodite genitalia developmentGO:00400357340.276
regulation of cellular biosynthetic processGO:00313261890.268
positive regulation of transcription dna templatedGO:00458931020.264
Human Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459351340.251
Human Mouse
positive regulation of cellular biosynthetic processGO:00313281090.251
Human Mouse
single organism signalingGO:00447004010.239
regulation of metabolic processGO:00192224780.233
reproductive structure developmentGO:00486088500.230
regulation of biosynthetic processGO:00098891890.227
cellular response to organic substanceGO:00713101190.219
endocytosisGO:00068978190.215
embryo developmentGO:000979030520.207
positive regulation of gene expressionGO:00106281120.207
Human Mouse
cellular macromolecule biosynthetic processGO:00346452470.205
multicellular organismal agingGO:00102598120.205
positive regulation of growthGO:00459273690.203
single organism reproductive processGO:004470211960.200
regulation of cellular macromolecule biosynthetic processGO:20001121880.196
cell cycleGO:00070495260.196
establishment of localizationGO:005123411710.192
nucleobase containing compound metabolic processGO:00061394060.182
cell proliferationGO:00082831160.180
signalingGO:00230524010.176
positive regulation of developmental processGO:00510944080.176
gene expressionGO:00104674120.176
vesicle mediated transportGO:00161928520.170
positive regulation of macromolecule biosynthetic processGO:00105571090.168
Human Mouse
negative regulation of gene expressionGO:00106292170.167
protein metabolic processGO:00195384220.164
macromolecule localizationGO:00330367710.164
rna metabolic processGO:00160702280.162
cellular nitrogen compound biosynthetic processGO:00442711920.159
determination of adult lifespanGO:00083408120.156
regulation of biological qualityGO:00650087410.155
regulation of transcription dna templatedGO:00063551640.154
development of primary sexual characteristicsGO:00451378400.153
nucleobase containing compound biosynthetic processGO:00346541840.150
organic substance biosynthetic processGO:19015763230.149
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.149
Human
regulation of nitrogen compound metabolic processGO:00511712220.148
sex differentiationGO:00075489090.148
locomotionGO:004001116340.143
signal transductionGO:00071653170.142
positive regulation of biosynthetic processGO:00098911090.137
Human Mouse
nucleic acid metabolic processGO:00903042990.135
regulation of rna metabolic processGO:00512521730.134
regulation of gene expressionGO:00104683660.130
biosynthetic processGO:00090583230.128
intracellular signal transductionGO:0035556960.127
cell morphogenesisGO:00009021630.126
transcription from rna polymerase ii promoterGO:00063661490.124
agingGO:00075688120.123
positive regulation of developmental growthGO:00486393540.118
regulation of multicellular organismal processGO:00512397260.118
transportGO:000681010930.116
positive regulation of rna biosynthetic processGO:19026801020.116
Human Mouse
regulation of macromolecule biosynthetic processGO:00105561890.114
regulation of nucleobase containing compound metabolic processGO:00192192220.113
response to transforming growth factor betaGO:0071559130.110
regulation of developmental processGO:00507936840.110
negative regulation of cellular processGO:00485232390.109
multicellular organism growthGO:00352643850.108
transcription dna templatedGO:00063511680.108
negative regulation of metabolic processGO:00098922400.107
regulation of cell communicationGO:00106461760.107
negative regulation of biological processGO:00485195670.100
body morphogenesisGO:00101716200.100
multicellular organismal reproductive processGO:00486098150.100
microtubule based processGO:00070171820.097
positive regulation of nitrogen compound metabolic processGO:00511731340.095
Human Mouse
genitalia developmentGO:00488067410.095
protein localizationGO:00081042050.092
reproductive system developmentGO:00614588500.091
apoptotic processGO:00069154780.090
heterocycle biosynthetic processGO:00181301870.090
positive regulation of multicellular organismal processGO:00512404170.088
regulation of signal transductionGO:00099661350.086
negative regulation of rna metabolic processGO:0051253530.085
developmental growthGO:00485894120.084
growthGO:00400075620.083
single organism localizationGO:19025785180.082
cellular response to chemical stimulusGO:00708871290.082
cell surface receptor signaling pathwayGO:00071661490.080
neuron differentiationGO:00301822170.080
catabolic processGO:00090563180.079
gamete generationGO:00072764610.078
embryo development ending in birth or egg hatchingGO:000979229920.077
cell cycle processGO:00224024820.074
protein complex subunit organizationGO:00718222800.073
organ morphogenesisGO:0009887670.073
sexual reproductionGO:00199535460.073
multi organism reproductive processGO:00447038670.072
phosphate containing compound metabolic processGO:00067962320.071
regulation of response to stimulusGO:00485832430.071
regulation of rna biosynthetic processGO:20011411650.071
defense responseGO:00069522960.071
regulation of multicellular organism growthGO:00400143730.070
regulation of signalingGO:00230511720.070
aromatic compound biosynthetic processGO:00194381920.068
phosphorus metabolic processGO:00067932320.068
cell deathGO:00082195470.067
establishment of localization in cellGO:00516493180.067
maintenance of locationGO:00512355800.066
positive regulation of cell communicationGO:0010647690.066
lipid localizationGO:00108765730.066
cellular component biogenesisGO:00440852970.065
single organism organelle organizationGO:19025895010.064
tissue morphogenesisGO:0048729650.064
developmental process involved in reproductionGO:000300611650.063
programmed cell deathGO:00125015000.063
enzyme linked receptor protein signaling pathwayGO:0007167500.063
lipid storageGO:00199155650.062
regulation of nucleic acid templated transcriptionGO:19035061650.061
protein complex assemblyGO:00064611860.060
establishment of spindle localizationGO:0051293510.060
small gtpase mediated signal transductionGO:0007264320.060
regulation of cellular component organizationGO:00511282480.060
lipid metabolic processGO:0006629770.060
cell developmentGO:00484686960.059
nervous system developmentGO:00073992530.059
cellular response to growth factor stimulusGO:0071363180.057
single organism behaviorGO:0044708830.057
organic substance catabolic processGO:19015752940.056
cellular component assemblyGO:00226072930.055
regulation of apoptotic processGO:0042981360.055
negative regulation of cellular metabolic processGO:0031324950.053
single organism transportGO:00447654470.053
negative regulation of nematode larval developmentGO:00610642080.052
deathGO:00162655470.052
regulation of cell differentiationGO:0045595810.052
cellular localizationGO:00516413600.051
positive regulation of multicellular organism growthGO:00400183520.051
regulation of growthGO:00400084090.050
macromolecular complex subunit organizationGO:00439333200.049
response to chemicalGO:00422213560.048
positive regulation of rna metabolic processGO:00512541030.048
Human Mouse
regulation of epithelial cell proliferationGO:005067810.047
negative regulation of response to stimulusGO:0048585730.047
cell projection morphogenesisGO:00488581480.046
organonitrogen compound metabolic processGO:19015641510.046
response to external stimulusGO:00096052890.045
response to organic substanceGO:00100331310.045
digestive tract developmentGO:00485651220.044
macromolecule biosynthetic processGO:00090592500.044
germ cell developmentGO:00072813510.043
organelle organizationGO:00069967830.042
organic substance transportGO:00717021130.042
negative regulation of rna biosynthetic processGO:1902679530.042
anatomical structure formation involved in morphogenesisGO:00486462500.041
Mouse
negative regulation of macromolecule metabolic processGO:00106052290.041
regulation of multicellular organismal developmentGO:20000263170.041
gastrulationGO:0007369580.041
asymmetric protein localizationGO:0008105350.041
regulation of intracellular signal transductionGO:1902531770.041
receptor mediated endocytosisGO:00068987150.040
cellular response to transforming growth factor beta stimulusGO:0071560130.040
regulation of catalytic activityGO:0050790780.040
cell divisionGO:00513012620.040
regulation of cell proliferationGO:00421271050.040
cytoskeleton organizationGO:00070103390.040
nucleic acid templated transcriptionGO:00976591690.039
negative regulation of macromolecule biosynthetic processGO:0010558650.039
adult locomotory behaviorGO:000834410.039
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361820.039
mitotic cell cycle processGO:19030471940.038
regulation of anatomical structure morphogenesisGO:0022603510.037
sensory organ morphogenesisGO:009059620.037
macromolecular complex assemblyGO:00650031930.037
molting cycleGO:00423032810.037
tube morphogenesisGO:0035239790.036
negative regulation of developmental processGO:00510932270.036
behaviorGO:00076105270.036
protein targeting to membraneGO:000661210.036
regulation of developmental growthGO:00486383890.036
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.035
apical junction assemblyGO:004329710.035
transforming growth factor beta receptor signaling pathwayGO:0007179130.034
dauer larval developmentGO:0040024920.034
regulation of gene expression epigeneticGO:00400291630.033
cell type specific apoptotic processGO:009728540.033
gene silencingGO:00164581430.033
immune responseGO:00069551920.032
cellular component morphogenesisGO:00329893180.032
response to biotic stimulusGO:00096071010.032
protein complex biogenesisGO:00702711860.032
establishment or maintenance of cell polarityGO:0007163630.032
regulation of cellular protein metabolic processGO:0032268750.032
regulation of cell cycleGO:00517261940.031
negative regulation of cell communicationGO:0010648610.031
gonad developmentGO:00084068400.031
vulval developmentGO:00400253330.030
developmental growth involved in morphogenesisGO:0060560370.030
organelle localizationGO:00516401270.030
epithelial tube morphogenesisGO:006056210.030
digestive tract morphogenesisGO:0048546760.029
regulation of protein metabolic processGO:0051246810.029
positive regulation of epithelial cell proliferationGO:005067910.028
multicellular organism reproductionGO:00325048190.028
membrane depolarizationGO:005189910.028
protein modification processGO:00362112070.028
neuron projection morphogenesisGO:00488121140.027
tissue developmentGO:00098881120.027
positive regulation of stem cell differentiationGO:200073810.027
response to abiotic stimulusGO:00096281520.026
establishment of cell polarityGO:0030010460.026
post embryonic organ developmentGO:00485693360.026
cell migrationGO:00164773060.026
neurogenesisGO:00220082360.026
cellular protein metabolic processGO:00442672790.026
response to growth factorGO:0070848180.026
cell cell signalingGO:00072671180.026
generation of neuronsGO:00486992350.026
regulation of phosphate metabolic processGO:0019220810.026
localization of cellGO:00516743130.026
regulation of organelle organizationGO:00330431640.025
regulation of organ morphogenesisGO:200002740.025
response to woundingGO:000961140.025
Mouse
neuron developmentGO:00486661990.025
regulation of cell morphogenesisGO:0022604400.024
head developmentGO:006032210.024
canonical wnt signaling pathwayGO:006007030.024
negative regulation of nucleobase containing compound metabolic processGO:0045934630.024
negative regulation of nitrogen compound metabolic processGO:0051172630.024
molting cycle collagen and cuticulin based cuticleGO:00189962810.024
secretion by cellGO:00329401380.023
membrane organizationGO:00610241350.023
cellular response to stressGO:00335541620.023
cellular component movementGO:00069283880.023
neuromuscular junction developmentGO:000752820.023
cell adhesionGO:0007155210.022
female gamete generationGO:00072922540.022
negative regulation of signal transductionGO:0009968600.022
protein phosphorylationGO:0006468850.022
intracellular receptor signaling pathwayGO:003052220.022
negative regulation of cellular biosynthetic processGO:0031327650.021
adult behaviorGO:003053430.021
response to external biotic stimulusGO:00432071010.021
synaptic growth at neuromuscular junctionGO:005112410.020
establishment of mitotic spindle localizationGO:0040001410.020
microtubule based transportGO:0010970190.020
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.020
macromolecule catabolic processGO:00090572020.020
neuron projection developmentGO:00311751870.019
regulation of mitotic cell cycleGO:0007346760.019
digestive system developmentGO:00551231220.019
negative regulation of signalingGO:0023057610.019
ribosome biogenesisGO:004225440.019
multi organism reproductive behaviorGO:00447053870.018
cellular response to endogenous stimulusGO:0071495320.018
ras protein signal transductionGO:0007265310.018
positive regulation of phosphate metabolic processGO:0045937560.018
regulation of cell fate specificationGO:0042659220.018
axon developmentGO:00615641630.018
establishment of organelle localizationGO:00516561230.018
regulation of cell cycle processGO:00105641450.018
reproductive behaviorGO:00190983870.018
negative regulation of nucleic acid templated transcriptionGO:1903507530.018
defense response to bacteriumGO:0042742860.018
establishment of protein localization to membraneGO:009015030.018
axonogenesisGO:00074091020.017
spindle localizationGO:0051653510.017
intraspecies interaction between organismsGO:005170330.017
regulation of nuclear divisionGO:00517831150.017
regulation of bmp signaling pathwayGO:003051030.017
secretionGO:00469031470.017
epidermal cell fate specificationGO:000995750.017
regulation of post embryonic developmentGO:00485802600.017
negative regulation of post embryonic developmentGO:00485812080.017
cellular catabolic processGO:00442481990.017
organelle fissionGO:00482853630.016
nucleobase containing compound catabolic processGO:00346551140.016
mitotic spindle organizationGO:0007052810.016
endoderm developmentGO:0007492200.016
aromatic compound catabolic processGO:00194391160.016
cellular process involved in reproduction in multicellular organismGO:00224123510.016
peptide hormone processingGO:001648620.015
regulation of phosphorylationGO:0042325450.015
positive regulation of signalingGO:0023056660.015
organic cyclic compound catabolic processGO:19013611190.015
cell motilityGO:00488703130.015
purine ribonucleoside triphosphate catabolic processGO:0009207720.015
regulation of molecular functionGO:0065009890.015
heterocycle catabolic processGO:00467001190.015
cell morphogenesis involved in differentiationGO:00009041120.015
posttranscriptional gene silencingGO:00164411430.015
biological adhesionGO:0022610210.015
positive regulation of protein transportGO:005122240.014
pigmentationGO:004347320.014
wnt signaling pathwayGO:0016055270.014
regulation of phosphorus metabolic processGO:0051174810.014
positive regulation of catalytic activityGO:0043085590.014
positive regulation of synapse assemblyGO:005196510.014
posttranscriptional gene silencing by rnaGO:00351941430.014
negative regulation of biosynthetic processGO:0009890650.014
memoryGO:000761330.014
defense response to other organismGO:00985421000.014
regulation of cell deathGO:0010941650.014
regulation of epithelial cell differentiationGO:003085640.014
regulation of cytoskeleton organizationGO:0051493410.014
rna processingGO:0006396340.014
stress activated mapk cascadeGO:0051403100.014
regulation of apoptotic signaling pathwayGO:200123310.013
macromolecule modificationGO:00434122180.013
gene silencing by rnaGO:00310471430.013
regulation of cell divisionGO:00513021420.013
tube developmentGO:00352951260.013
chromosome organizationGO:00512761040.013
cuticle developmentGO:00423351000.013
phosphorylationGO:00163101160.013
positive regulation of catabolic processGO:0009896380.013
positive regulation of cell projection organizationGO:003134640.013
positive regulation of cell cycleGO:0045787550.013
cell projection organizationGO:00300302310.013
ovipositionGO:00189913640.013
regulation of protein modification processGO:0031399460.013
cellular macromolecular complex assemblyGO:00346221840.013
neuron apoptotic processGO:005140240.012
positive regulation of transferase activityGO:0051347210.012
organism emergence from protective structureGO:0071684480.012
inductive cell migrationGO:00400391450.012
mapk cascadeGO:0000165310.012
cell part morphogenesisGO:00329901520.012
asymmetric protein localization involved in cell fate determinationGO:0045167180.012
carbohydrate derivative metabolic processGO:19011351410.012
regulation of lipid metabolic processGO:001921640.012
phagocytosisGO:00069091150.012
regulation of gastrulationGO:001047040.012
small molecule metabolic processGO:00442811860.012
regulation of nervous system developmentGO:0051960410.012
regulation of programmed cell deathGO:0043067500.012
axon guidanceGO:0007411820.012
regulation of dna templated transcription in response to stressGO:004362030.012
multi organism behaviorGO:00517053890.012
cellular protein modification processGO:00064642070.012
regulation of synapse assemblyGO:005196320.011
negative regulation of vulval developmentGO:00400272060.011
synaptic transmissionGO:00072681060.011
insulin metabolic processGO:190114220.011
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600320.011
mesoderm morphogenesisGO:0048332240.011
regulation of cellular response to growth factor stimulusGO:0090287110.011
membrane invaginationGO:0010324980.011
social behaviorGO:003517630.011
glycosyl compound metabolic processGO:19016571000.011
cell fate commitment involved in formation of primary germ layerGO:0060795330.011
collagen and cuticulin based cuticle developmentGO:0040002990.011
negative regulation of multicellular organismal processGO:00512412360.011
single organism membrane organizationGO:0044802350.011
male sex differentiationGO:0046661860.011
cellular nitrogen compound catabolic processGO:00442701190.011
embryonic morphogenesisGO:00485981520.011
positive regulation of protein metabolic processGO:0051247450.011
establishment of protein localizationGO:0045184500.011
response to other organismGO:00517071010.011
glycosyl compound catabolic processGO:1901658790.011
response to bacteriumGO:0009617860.011
cytokinesisGO:0000910800.011
purine nucleotide metabolic processGO:0006163950.011
response to endogenous stimulusGO:0009719330.010
cellular amide metabolic processGO:0043603110.010
cellular response to nitrogen compoundGO:1901699240.010
oogenesisGO:00484772290.010
rna interferenceGO:00162461370.010
regulation of cell projection organizationGO:0031344380.010
male anatomical structure morphogenesisGO:0090598780.010
positive regulation of cell differentiationGO:004559780.010
innate immune responseGO:00450871900.010
cell morphogenesis involved in neuron differentiationGO:00486671110.010

lin-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
disease of cellular proliferationDOID:1456600.020
musculoskeletal system diseaseDOID:1700.014
organ system cancerDOID:005068600.013
cancerDOID:16200.013
cardiovascular system diseaseDOID:128700.012