Caenorhabditis elegans

130 known processes

unc-130 (CELE_C47G2.2)

Protein UNC-130

unc-130 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.608
post embryonic developmentGO:000979121520.561
Worm
embryo developmentGO:000979030520.527
positive regulation of rna biosynthetic processGO:19026801020.447
Mouse Worm
locomotionGO:004001116340.435
organ developmentGO:004851311020.390
Zebrafish Mouse Worm
gonad developmentGO:00084068400.363
Worm
digestive tract developmentGO:00485651220.354
Worm
cell migrationGO:00164773060.352
Zebrafish
neuron projection guidanceGO:0097485820.309
sex differentiationGO:00075489090.300
regulation of nitrogen compound metabolic processGO:00511712220.293
body morphogenesisGO:00101716200.291
Worm
regulation of nucleobase containing compound metabolic processGO:00192192220.275
single organism reproductive processGO:004470211960.269
Mouse Worm
transcription dna templatedGO:00063511680.263
cell developmentGO:00484686960.262
reproductive structure developmentGO:00486088500.262
Mouse Worm
multicellular organism reproductionGO:00325048190.255
Worm
cell motilityGO:00488703130.254
Zebrafish
localization of cellGO:00516743130.242
Zebrafish
nervous system developmentGO:00073992530.237
head developmentGO:006032210.230
positive regulation of metabolic processGO:00098931870.225
Mouse Worm
regulation of developmental processGO:00507936840.224
Mouse Worm
behaviorGO:00076105270.219
Worm
single organism organelle organizationGO:19025895010.218
Worm
sensory organ morphogenesisGO:009059620.216
multicellular organismal reproductive processGO:00486098150.209
Worm
regulation of rna metabolic processGO:00512521730.202
mesodermal cell fate specificationGO:0007501130.195
Worm
rna metabolic processGO:00160702280.192
developmental process involved in reproductionGO:000300611650.192
organelle organizationGO:00069967830.190
Worm
negative regulation of biological processGO:00485195670.179
organ morphogenesisGO:0009887670.177
Zebrafish Mouse
ovipositionGO:00189913640.175
Worm
development of primary sexual characteristicsGO:00451378400.173
Worm
tube morphogenesisGO:0035239790.172
Mouse Worm
organic cyclic compound biosynthetic processGO:19013621950.169
hermaphrodite genitalia developmentGO:00400357340.167
Worm
regulation of multicellular organismal processGO:00512397260.167
Mouse Worm
positive regulation of cellular processGO:00485223320.166
Mouse Worm
cellular component movementGO:00069283880.164
axon developmentGO:00615641630.164
cell cycleGO:00070495260.161
neurogenesisGO:00220082360.160
multi organism behaviorGO:00517053890.157
Worm
regulation of biosynthetic processGO:00098891890.153
reproductive system developmentGO:00614588500.151
Mouse Worm
genitalia developmentGO:00488067410.150
Worm
gastrulationGO:0007369580.148
Worm
positive regulation of macromolecule metabolic processGO:00106041490.145
Mouse Worm
heterocycle biosynthetic processGO:00181301870.144
mesodermal cell differentiationGO:0048333150.141
Worm
programmed cell deathGO:00125015000.137
positive regulation of nitrogen compound metabolic processGO:00511731340.137
Mouse Worm
establishment of localizationGO:005123411710.134
Worm
developmental growthGO:00485894120.133
embryonic morphogenesisGO:00485981520.131
Worm
multi organism reproductive behaviorGO:00447053870.131
Worm
cell fate commitment involved in formation of primary germ layerGO:0060795330.130
Worm
positive regulation of transcription dna templatedGO:00458931020.128
Mouse Worm
regulation of developmental growthGO:00486383890.125
Worm
multi multicellular organism processGO:00447063900.125
Worm
determination of adult lifespanGO:00083408120.123
Worm
macromolecule biosynthetic processGO:00090592500.122
axon guidanceGO:0007411820.121
regulation of cellular macromolecule biosynthetic processGO:20001121880.121
regulation of biological qualityGO:00650087410.120
transcription from rna polymerase ii promoterGO:00063661490.119
multicellular organism growthGO:00352643850.119
Worm
gene expressionGO:00104674120.119
epithelium developmentGO:0060429680.117
Zebrafish Mouse
positive regulation of multicellular organism growthGO:00400183520.117
Worm
nucleobase containing compound metabolic processGO:00061394060.112
positive regulation of cellular biosynthetic processGO:00313281090.108
Mouse Worm
multicellular organismal agingGO:00102598120.107
Worm
tissue morphogenesisGO:0048729650.107
Mouse Worm
regulation of metabolic processGO:00192224780.107
tissue developmentGO:00098881120.107
Zebrafish Mouse Worm
mesoderm developmentGO:0007498270.106
Worm
sexual reproductionGO:00199535460.106
growthGO:00400075620.104
digestive tract morphogenesisGO:0048546760.103
Worm
neuron developmentGO:00486661990.101
nonmotile primary cilium assemblyGO:0035058180.100
Worm
apoptotic processGO:00069154780.098
regulation of multicellular organism growthGO:00400143730.097
Worm
nucleic acid metabolic processGO:00903042990.095
positive regulation of cellular metabolic processGO:00313251780.094
Mouse Worm
positive regulation of multicellular organismal processGO:00512404170.093
Mouse Worm
vulval developmentGO:00400253330.090
Worm
macromolecule localizationGO:00330367710.090
regenerationGO:003109940.089
reproductive behaviorGO:00190983870.089
Worm
regulation of gene expressionGO:00104683660.089
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.088
Mouse Worm
cell deathGO:00082195470.087
tube developmentGO:00352951260.086
Mouse Worm
response to woundingGO:000961140.084
receptor mediated endocytosisGO:00068987150.082
Worm
epithelial tube morphogenesisGO:006056210.082
Mouse
cell projection organizationGO:00300302310.081
cell cycle processGO:00224024820.081
post embryonic organ developmentGO:00485693360.081
Worm
chemotaxisGO:00069351200.080
endocytosisGO:00068978190.078
Worm
cellular component morphogenesisGO:00329893180.077
aromatic compound biosynthetic processGO:00194381920.075
multi organism reproductive processGO:00447038670.075
Worm
positive regulation of developmental processGO:00510944080.074
Mouse Worm
negative regulation of biosynthetic processGO:0009890650.073
cellular macromolecule biosynthetic processGO:00346452470.073
positive regulation of signal transductionGO:0009967400.073
Mouse
negative regulation of developmental processGO:00510932270.071
Worm
lipid localizationGO:00108765730.070
deathGO:00162655470.069
regulation of macromolecule metabolic processGO:00602554210.069
cellular nitrogen compound biosynthetic processGO:00442711920.068
positive regulation of biosynthetic processGO:00098911090.066
Mouse Worm
positive regulation of growthGO:00459273690.066
Worm
inductive cell migrationGO:00400391450.066
digestive system developmentGO:00551231220.066
Worm
negative regulation of nematode larval developmentGO:00610642080.065
Worm
embryonic body morphogenesisGO:0010172490.065
establishment of localization in cellGO:00516493180.065
transportGO:000681010930.065
Worm
organic substance biosynthetic processGO:19015763230.064
positive regulation of gene expressionGO:00106281120.064
Mouse Worm
signal transductionGO:00071653170.064
Mouse
neuron differentiationGO:00301822170.063
positive regulation of cell migrationGO:003033530.063
cell fate commitmentGO:00451651390.063
Worm
lipid storageGO:00199155650.063
regulation of primary metabolic processGO:00800902920.062
regulation of growthGO:00400084090.062
Worm
epidermal cell fate specificationGO:000995750.062
macromolecular complex subunit organizationGO:00439333200.060
pattern specification processGO:0007389590.060
Mouse Worm
vesicle mediated transportGO:00161928520.060
Worm
regulation of macromolecule biosynthetic processGO:00105561890.059
positive regulation of nucleobase containing compound metabolic processGO:00459351340.059
Mouse Worm
pharynx developmentGO:0060465510.058
Worm
maintenance of locationGO:00512355800.058
regulation of rna biosynthetic processGO:20011411650.058
molting cycle collagen and cuticulin based cuticleGO:00189962810.058
gamete generationGO:00072764610.057
negative regulation of vulval developmentGO:00400272060.057
Worm
positive regulation of neurogenesisGO:005076940.056
regulation of post embryonic developmentGO:00485802600.056
Worm
regulation of transcription dna templatedGO:00063551640.054
multicellular organismal reproductive behaviorGO:00330573840.054
Worm
positive regulation of transcription from rna polymerase ii promoter in response to increased saltGO:006140410.053
muscle tissue developmentGO:006053710.052
biosynthetic processGO:00090583230.052
anterior posterior pattern specificationGO:0009952270.051
single organism signalingGO:00447004010.051
Mouse
response to chemicalGO:00422213560.050
regulation of transcription from rna polymerase ii promoterGO:00063571450.049
cell type specific apoptotic processGO:009728540.049
positive regulation of nucleic acid templated transcriptionGO:19035081020.048
Mouse Worm
regulation of cellular metabolic processGO:00313233050.048
negative regulation of gene expressionGO:00106292170.048
mitotic cell cycle processGO:19030471940.048
female gamete generationGO:00072922540.047
positive regulation of transcription from rna polymerase ii promoter in response to salt stressGO:003625110.047
negative regulation of post embryonic developmentGO:00485812080.046
Worm
positive regulation of transcription from rna polymerase ii promoter involved in defense response to fungusGO:190124410.045
generation of neuronsGO:00486992350.045
negative regulation of metabolic processGO:00098922400.045
regulation of nematode larval developmentGO:00610622600.044
Worm
axonogenesisGO:00074091020.044
agingGO:00075688120.043
Worm
organic substance catabolic processGO:19015752940.043
regulation of transcription from rna polymerase ii promoter in response to salt stressGO:006141610.042
germ cell developmentGO:00072813510.042
cellular response to abiotic stimulusGO:007121440.042
response to external stimulusGO:00096052890.041
positive regulation of developmental growthGO:00486393540.040
Worm
nucleic acid templated transcriptionGO:00976591690.040
skeletal muscle organ developmentGO:006053830.040
regulation of nucleic acid templated transcriptionGO:19035061650.040
muscle structure developmentGO:00610611910.039
regulation of cellular biosynthetic processGO:00313261890.039
negative regulation of multicellular organismal processGO:00512412360.039
Worm
positive regulation of neuron differentiationGO:004566640.039
regulation of multicellular organismal developmentGO:20000263170.038
Mouse Worm
chemosensory behaviorGO:0007635330.038
anatomical structure formation involved in morphogenesisGO:00486462500.036
Mouse Worm
negative regulation of neurogenesisGO:005076840.036
positive regulation of epithelial cell proliferationGO:005067910.035
regulation of gastrulationGO:001047040.035
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139310.035
regulation of cellular component organizationGO:00511282480.035
taxisGO:00423301280.034
regulation of response to stimulusGO:00485832430.034
Mouse Worm
negative regulation of cellular processGO:00485232390.033
cell morphogenesis involved in neuron differentiationGO:00486671110.033
single organism localizationGO:19025785180.033
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600320.033
cilium morphogenesisGO:0060271330.032
Worm
cellular localizationGO:00516413600.032
organelle fissionGO:00482853630.032
neuron projection extension involved in neuron projection guidanceGO:1902284130.032
response to abiotic stimulusGO:00096281520.032
regulation of epithelial cell proliferationGO:005067810.032
negative regulation of rna biosynthetic processGO:1902679530.031
nematode male tail tip morphogenesisGO:0045138770.031
negative regulation of nucleobase containing compound metabolic processGO:0045934630.031
molting cycleGO:00423032810.031
cellular hyperosmotic salinity responseGO:007147510.031
regulation of cell proliferationGO:00421271050.031
regulation of cell cycleGO:00517261940.030
protein localizationGO:00081042050.030
axon extension involved in axon guidanceGO:0048846130.029
negative regulation of macromolecule biosynthetic processGO:0010558650.029
cell divisionGO:00513012620.029
cell morphogenesis involved in differentiationGO:00009041120.029
cellular protein metabolic processGO:00442672790.028
Worm
regulation of vulval developmentGO:00400282480.028
Worm
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.028
positive regulation of macromolecule biosynthetic processGO:00105571090.028
Mouse Worm
neuron fate specificationGO:004866580.028
Worm
negative regulation of macromolecule metabolic processGO:00106052290.028
neuron projection morphogenesisGO:00488121140.028
regulation of cell differentiationGO:0045595810.028
cytoskeleton organizationGO:00070103390.027
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361820.027
regulation of programmed cell deathGO:0043067500.027
cellular response to stressGO:00335541620.027
Worm
protein metabolic processGO:00195384220.027
Worm
cellular biosynthetic processGO:00442493150.026
axonal fasciculationGO:0007413790.026
hormone transportGO:000991420.026
cellular component assemblyGO:00226072930.026
Worm
cellular component biogenesisGO:00440852970.026
Worm
muscle cell differentiationGO:00426921710.026
regulation of signal transductionGO:00099661350.025
Mouse
neuron recognitionGO:0008038830.025
actin filament based processGO:00300291910.025
negative regulation of cellular biosynthetic processGO:0031327650.025
regulation of gene expression epigeneticGO:00400291630.025
regulation of locomotionGO:00400121610.025
regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139210.024
nucleobase containing compound biosynthetic processGO:00346541840.024
biological adhesionGO:0022610210.024
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacteriumGO:190209740.024
regulation of cell migrationGO:0030334550.024
cell morphogenesisGO:00009021630.024
regulation of localizationGO:00328791940.023
cellular process involved in reproduction in multicellular organismGO:00224123510.023
negative regulation of transcription dna templatedGO:0045892530.023
membrane organizationGO:00610241350.023
organonitrogen compound metabolic processGO:19015641510.023
gabaergic neuron differentiationGO:009715410.022
cell fate specification involved in pattern specificationGO:006057340.022
Worm
signalingGO:00230524010.022
Mouse
microtubule based processGO:00070171820.022
positive regulation of signalingGO:0023056660.022
Mouse
negative regulation of nucleic acid templated transcriptionGO:1903507530.021
endodermal cell fate determinationGO:000749320.021
olfactory behaviorGO:0042048270.021
neuron projection developmentGO:00311751870.021
striated muscle cell differentiationGO:00511461580.021
catabolic processGO:00090563180.021
Worm
positive regulation of intracellular signal transductionGO:1902533240.021
male sex differentiationGO:0046661860.021
protein complex biogenesisGO:00702711860.021
positive regulation of embryonic developmentGO:004001930.021
oogenesisGO:00484772290.021
regionalizationGO:0003002310.021
Mouse
cellular component assembly involved in morphogenesisGO:00109271830.020
Worm
muscle organ morphogenesisGO:004864440.020
regulation of sequence specific dna binding transcription factor activityGO:005109030.020
neuroblast fate determinationGO:000740010.020
canonical wnt signaling pathwayGO:006007030.020
positive regulation of stem cell differentiationGO:200073810.020
cell part morphogenesisGO:00329901520.020
tube formationGO:003514820.020
intracellular transportGO:0046907770.020
macromolecule catabolic processGO:00090572020.020
protein complex subunit organizationGO:00718222800.020
cell adhesionGO:0007155210.020
development of primary male sexual characteristicsGO:004654640.019
Worm
regulation of cell cycle processGO:00105641450.019
hindgut developmentGO:006152530.019
regulation of epithelial cell differentiationGO:003085640.019
gene silencingGO:00164581430.019
epithelial cell proliferationGO:005067310.019
organelle assemblyGO:00709252140.019
Worm
cellular response to nutrient levelsGO:0031669130.018
Worm
plasma membrane fusionGO:004502650.018
regulation of neuron differentiationGO:0045664400.018
regulation of embryonic developmentGO:0045995160.018
protein complex assemblyGO:00064611860.017
cell surface receptor signaling pathwayGO:00071661490.017
Mouse
meiotic cell cycleGO:00513213350.017
cell proliferationGO:00082831160.017
negative regulation of neuron differentiationGO:004566540.017
neural precursor cell proliferationGO:006135190.017
endoderm developmentGO:0007492200.017
positive regulation of rna metabolic processGO:00512541030.017
Mouse Worm
regulation of organ morphogenesisGO:200002740.017
embryonic pattern specificationGO:0009880210.016
chromosome organizationGO:00512761040.016
vulval locationGO:003460860.016
organonitrogen compound biosynthetic processGO:1901566440.016
regulation of organelle organizationGO:00330431640.016
bmp signaling pathwayGO:003050930.016
Mouse
mechanosensory behaviorGO:0007638250.016
striated muscle myosin thick filament assemblyGO:00716881380.016
actin cytoskeleton organizationGO:00300361840.016
macromolecule modificationGO:00434122180.016
adult behaviorGO:003053430.015
regulation of response to woundingGO:190303410.015
internal peptidyl lysine acetylationGO:001839330.015
regulation of fibroblast growth factor receptor signaling pathwayGO:004003620.015
pigmentationGO:004347320.015
Zebrafish
posttranscriptional gene silencing by rnaGO:00351941430.015
detection of external stimulusGO:000958140.015
protein modification processGO:00362112070.015
muscle cell developmentGO:00550011580.015
myofibril assemblyGO:00302391540.015
system processGO:00030081360.015
myosin filament assemblyGO:00310341380.015
secretion by cellGO:00329401380.015
proximal distal pattern formationGO:000995460.015
regulation of apoptotic signaling pathwayGO:200123310.015
regulation of molecular functionGO:0065009890.015
skin developmentGO:0043588240.015
mitotic spindle organizationGO:0007052810.015
positive regulation of molecular functionGO:0044093610.015
dendrite developmentGO:0016358420.014
Worm
cellular protein complex assemblyGO:00436231780.014
rna biosynthetic processGO:00327741690.014
regulation of cellular ketone metabolic processGO:001056530.014
regulation of multi organism processGO:0043900690.014
negative regulation of nitrogen compound metabolic processGO:0051172630.014
neuroblast proliferationGO:000740590.014
striated muscle cell developmentGO:00550021570.014
negative regulation of cellular metabolic processGO:0031324950.014
actomyosin structure organizationGO:00310321540.014
rna interferenceGO:00162461370.014
myosin filament organizationGO:00310331380.014
collagen and cuticulin based cuticle developmentGO:0040002990.014
Worm
phenol containing compound biosynthetic processGO:004618980.014
macromolecular complex assemblyGO:00650031930.014
cell cell signalingGO:00072671180.014
male anatomical structure morphogenesisGO:0090598780.014
regulation of cytoplasmic transportGO:190364930.014
positive regulation of protein metabolic processGO:0051247450.013
Worm
regulation of intracellular signal transductionGO:1902531770.013
gene silencing by rnaGO:00310471430.013
secretionGO:00469031470.013
covalent chromatin modificationGO:0016569300.013
cellular response to metal ionGO:007124830.013
organelle localizationGO:00516401270.013
single organism behaviorGO:0044708830.013
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.013
negative regulation of rna metabolic processGO:0051253530.013
regulation of nucleocytoplasmic transportGO:004682230.013
regulation of signalingGO:00230511720.013
Mouse
carboxylic acid metabolic processGO:0019752340.013
epidermis developmentGO:0008544240.013
synaptic target recognitionGO:000803930.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.013
regulation of cell motilityGO:2000145570.012
neuron apoptotic processGO:005140240.012
positive regulation of locomotionGO:0040017420.012
posttranscriptional regulation of gene expressionGO:00106081660.012
Worm
single organism biosynthetic processGO:0044711910.012
carbohydrate derivative metabolic processGO:19011351410.012
regulation of cell communicationGO:00106461760.012
Mouse Worm
positive regulation of cell cycleGO:0045787550.012
asymmetric cell divisionGO:0008356360.012
establishment of nucleus localizationGO:0040023550.012
regulation of protein metabolic processGO:0051246810.012
Worm
adult locomotory behaviorGO:000834410.012
posttranscriptional gene silencingGO:00164411430.012
male gonad developmentGO:000858440.012
Worm
single organism transportGO:00447654470.012
regulation of synaptic plasticityGO:004816710.012
hormone secretionGO:004687920.012
mitotic nuclear divisionGO:0007067890.012
cellular macromolecular complex assemblyGO:00346221840.012
spindle organizationGO:0007051920.012
muscle fiber developmentGO:004874720.011
organic substance transportGO:00717021130.011
phosphate containing compound metabolic processGO:00067962320.011
ovulationGO:0030728330.011
regulation of cell deathGO:0010941650.011
intracellular signal transductionGO:0035556960.011
protein catabolic processGO:00301631620.011
microtubule based movementGO:0007018330.011
positive regulation of protein transportGO:005122240.011
regulation of hormone secretionGO:004688320.011
negative regulation of locomotionGO:0040013210.011
phosphorus metabolic processGO:00067932320.011
nuclear migrationGO:0007097540.011
dauer larval developmentGO:0040024920.011
regulation of lipid metabolic processGO:001921640.011
synaptic growth at neuromuscular junctionGO:005112410.011
hindgut morphogenesisGO:000744230.011
cell substrate adhesionGO:003158910.011
cellular response to organic substanceGO:00713101190.011
positive regulation of intracellular transportGO:003238820.011
meiotic cell cycle processGO:19030461700.011
small molecule metabolic processGO:00442811860.011
organic cyclic compound catabolic processGO:19013611190.011
response to nutrient levelsGO:0031667350.011
Worm
stem cell proliferationGO:007208990.011
specification of axis polarityGO:0065001130.010
regulation of cell divisionGO:00513021420.010
cytoskeleton dependent intracellular transportGO:0030705190.010
positive regulation of catalytic activityGO:0043085590.010
segmentationGO:003528270.010
hormone metabolic processGO:004244530.010
cellular response to inorganic substanceGO:007124130.010
neuromuscular junction developmentGO:000752820.010
lipid metabolic processGO:0006629770.010
Worm
enzyme linked receptor protein signaling pathwayGO:0007167500.010
Mouse
meiotic nuclear divisionGO:00071263000.010
synaptic transmissionGO:00072681060.010
axon extensionGO:0048675370.010
axis specificationGO:0009798230.010

unc-130 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
disease of metabolismDOID:001466700.013
cardiovascular system diseaseDOID:128700.012
heart diseaseDOID:11400.012
myopathyDOID:42300.012
musculoskeletal system diseaseDOID:1700.012
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
cardiomyopathyDOID:005070000.012
nervous system diseaseDOID:86300.011