Caenorhabditis elegans

0 known processes

tmc-2 (CELE_B0416.1)

Protein TMC-2

tmc-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of nucleobase containing compound metabolic processGO:00459351340.374
multicellular organismal reproductive processGO:00486098150.363
signalingGO:00230524010.334
sexual reproductionGO:00199535460.299
single organism signalingGO:00447004010.275
axon developmentGO:00615641630.265
regulation of response to stimulusGO:00485832430.261
regulation of multicellular organismal processGO:00512397260.240
taxisGO:00423301280.233
neuron projection developmentGO:00311751870.223
embryo developmentGO:000979030520.210
positive regulation of neurogenesisGO:005076940.207
positive regulation of cell projection organizationGO:003134640.205
organ developmentGO:004851311020.194
axonogenesisGO:00074091020.191
cell surface receptor signaling pathwayGO:00071661490.187
positive regulation of multicellular organismal processGO:00512404170.181
cellular component movementGO:00069283880.180
cell migrationGO:00164773060.179
neuron differentiationGO:00301822170.179
regulation of cell communicationGO:00106461760.178
neuron projection morphogenesisGO:00488121140.177
cell morphogenesisGO:00009021630.173
regulation of multicellular organismal developmentGO:20000263170.172
neurotransmitter catabolic processGO:004213540.171
cellular component morphogenesisGO:00329893180.169
digestive tract morphogenesisGO:0048546760.169
nervous system developmentGO:00073992530.168
neurogenesisGO:00220082360.168
sex differentiationGO:00075489090.165
regulation of cell morphogenesisGO:0022604400.161
localization of cellGO:00516743130.161
positive regulation of gene expressionGO:00106281120.160
locomotionGO:004001116340.160
developmental process involved in reproductionGO:000300611650.158
behaviorGO:00076105270.157
cell developmentGO:00484686960.156
multi organism reproductive processGO:00447038670.155
cell morphogenesis involved in neuron differentiationGO:00486671110.154
chemotaxisGO:00069351200.152
cell projection organizationGO:00300302310.149
positive regulation of nitrogen compound metabolic processGO:00511731340.149
regulation of cellular component organizationGO:00511282480.148
positive regulation of cellular metabolic processGO:00313251780.147
post embryonic developmentGO:000979121520.146
growthGO:00400075620.145
nucleobase containing compound metabolic processGO:00061394060.145
positive regulation of metabolic processGO:00098931870.143
multi multicellular organism processGO:00447063900.142
single organism reproductive processGO:004470211960.140
positive regulation of macromolecule metabolic processGO:00106041490.139
tissue morphogenesisGO:0048729650.139
muscle tissue developmentGO:006053710.137
signal transductionGO:00071653170.134
embryo development ending in birth or egg hatchingGO:000979229920.131
muscle structure developmentGO:00610611910.130
neuron developmentGO:00486661990.130
apoptotic processGO:00069154780.129
positive regulation of neuron projection developmentGO:001097640.128
cell part morphogenesisGO:00329901520.124
establishment of localizationGO:005123411710.122
gamete generationGO:00072764610.115
cell morphogenesis involved in differentiationGO:00009041120.115
ovipositionGO:00189913640.114
agingGO:00075688120.114
response to external stimulusGO:00096052890.113
positive regulation of rna biosynthetic processGO:19026801020.113
regulation of biological qualityGO:00650087410.113
meiotic cell cycleGO:00513213350.112
cell motilityGO:00488703130.112
programmed cell deathGO:00125015000.111
regulation of catalytic activityGO:0050790780.111
positive regulation of cell morphogenesis involved in differentiationGO:001077040.111
protein complex subunit organizationGO:00718222800.109
positive regulation of neuron differentiationGO:004566640.109
gastrulationGO:0007369580.108
reproductive behaviorGO:00190983870.107
positive regulation of cellular processGO:00485223320.106
tube morphogenesisGO:0035239790.106
development of primary sexual characteristicsGO:00451378400.105
organelle organizationGO:00069967830.103
regulation of developmental processGO:00507936840.103
protein complex biogenesisGO:00702711860.098
cell deathGO:00082195470.098
cell projection morphogenesisGO:00488581480.096
multi organism behaviorGO:00517053890.095
mesoderm developmentGO:0007498270.095
negative regulation of multicellular organismal processGO:00512412360.093
cell fate commitmentGO:00451651390.093
negative regulation of developmental processGO:00510932270.091
epithelial tube morphogenesisGO:006056210.090
cytoskeleton organizationGO:00070103390.090
deathGO:00162655470.090
regulation of neurotransmitter levelsGO:0001505360.090
reproductive structure developmentGO:00486088500.088
regulation of cell morphogenesis involved in differentiationGO:0010769290.086
vesicle mediated transportGO:00161928520.086
single organism transportGO:00447654470.084
multicellular organismal reproductive behaviorGO:00330573840.083
single organism localizationGO:19025785180.082
tissue developmentGO:00098881120.082
epithelium developmentGO:0060429680.081
regulation of purine nucleotide catabolic processGO:0033121350.081
head developmentGO:006032210.081
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.080
multi organism reproductive behaviorGO:00447053870.080
macromolecule localizationGO:00330367710.080
meiotic nuclear divisionGO:00071263000.079
single organism organelle organizationGO:19025895010.079
regulation of molecular functionGO:0065009890.079
striated muscle cell developmentGO:00550021570.078
actin cytoskeleton organizationGO:00300361840.078
multicellular organism reproductionGO:00325048190.077
ribonucleoside triphosphate metabolic processGO:0009199870.077
cellular catabolic processGO:00442481990.076
positive regulation of multicellular organism growthGO:00400183520.075
digestive tract developmentGO:00485651220.075
generation of neuronsGO:00486992350.074
regulation of reproductive processGO:2000241660.073
positive regulation of growthGO:00459273690.073
regulation of nucleotide catabolic processGO:0030811350.072
cation transportGO:0006812780.072
tube developmentGO:00352951260.072
intracellular signal transductionGO:0035556960.071
purine ribonucleoside metabolic processGO:0046128920.071
establishment of localization in cellGO:00516493180.070
endocytosisGO:00068978190.070
regulation of neuron projection developmentGO:0010975310.070
regulation of gtp catabolic processGO:0033124320.068
positive regulation of molecular functionGO:0044093610.068
positive regulation of developmental processGO:00510944080.068
response to abiotic stimulusGO:00096281520.068
regulation of growthGO:00400084090.067
lipid localizationGO:00108765730.067
phosphate containing compound metabolic processGO:00067962320.066
purine nucleotide metabolic processGO:0006163950.066
multicellular organismal agingGO:00102598120.065
regulation of neuron differentiationGO:0045664400.064
regulation of phosphate metabolic processGO:0019220810.064
regulation of axon extensionGO:0030516200.064
protein complex assemblyGO:00064611860.064
phosphorus metabolic processGO:00067932320.063
negative regulation of biological processGO:00485195670.063
nucleotide metabolic processGO:00091171080.063
actin filament based processGO:00300291910.063
regulation of cellular component sizeGO:0032535400.062
germ cell developmentGO:00072813510.061
gene expressionGO:00104674120.061
regulation of nitrogen compound metabolic processGO:00511712220.061
cellular macromolecular complex assemblyGO:00346221840.060
lipid storageGO:00199155650.060
regulation of vulval developmentGO:00400282480.060
maintenance of locationGO:00512355800.059
transportGO:000681010930.059
cell cycleGO:00070495260.058
positive regulation of biosynthetic processGO:00098911090.058
cellular localizationGO:00516413600.058
regulation of anatomical structure morphogenesisGO:0022603510.057
cell cell signalingGO:00072671180.057
regulation of behaviorGO:0050795970.057
neuron recognitionGO:0008038830.056
macromolecular complex assemblyGO:00650031930.056
regulation of gene expressionGO:00104683660.055
positive regulation of cell communicationGO:0010647690.055
enzyme linked receptor protein signaling pathwayGO:0007167500.055
rho protein signal transductionGO:000726620.055
female gamete generationGO:00072922540.054
positive regulation of gtpase activityGO:0043547280.054
post embryonic organ developmentGO:00485693360.054
organelle assemblyGO:00709252140.053
determination of adult lifespanGO:00083408120.053
digestive system developmentGO:00551231220.053
positive regulation of phosphorus metabolic processGO:0010562560.053
regulation of signalingGO:00230511720.052
purine nucleoside triphosphate catabolic processGO:0009146720.052
developmental growthGO:00485894120.052
regulation of developmental growthGO:00486383890.052
positive regulation of neurotransmitter transportGO:0051590110.052
macromolecular complex subunit organizationGO:00439333200.051
myofibril assemblyGO:00302391540.051
cellular process involved in reproduction in multicellular organismGO:00224123510.051
protein localizationGO:00081042050.051
cell type specific apoptotic processGO:009728540.051
regulation of post embryonic developmentGO:00485802600.050
positive regulation of nucleic acid templated transcriptionGO:19035081020.050
regulation of metabolic processGO:00192224780.050
cellular component assembly involved in morphogenesisGO:00109271830.050
developmental growth involved in morphogenesisGO:0060560370.049
regulation of macromolecule metabolic processGO:00602554210.049
positive regulation of response to stimulusGO:0048584550.049
positive regulation of phosphate metabolic processGO:0045937560.049
reproductive system developmentGO:00614588500.049
synaptic transmissionGO:00072681060.048
muscle cell differentiationGO:00426921710.048
positive regulation of synaptic transmission dopaminergicGO:003222610.048
protein metabolic processGO:00195384220.048
cellular component assemblyGO:00226072930.047
aromatic compound catabolic processGO:00194391160.047
positive regulation of locomotionGO:0040017420.047
positive regulation of catalytic activityGO:0043085590.047
phosphorylationGO:00163101160.046
actomyosin structure organizationGO:00310321540.046
organelle fissionGO:00482853630.046
regulation of actin filament based processGO:0032970220.046
ribose phosphate metabolic processGO:0019693990.045
small gtpase mediated signal transductionGO:0007264320.045
nucleoside phosphate catabolic processGO:1901292770.044
regulation of anatomical structure sizeGO:0090066460.044
cell maturationGO:0048469260.044
guanosine containing compound metabolic processGO:1901068490.044
cellular macromolecule localizationGO:0070727750.044
regulation of signal transductionGO:00099661350.044
mechanosensory behaviorGO:0007638250.043
regulation of cell motilityGO:2000145570.043
cellular nitrogen compound biosynthetic processGO:00442711920.043
response to chemicalGO:00422213560.043
skeletal muscle organ developmentGO:006053830.043
positive regulation of cell developmentGO:001072060.043
positive regulation of nucleoside metabolic processGO:0045979280.043
nucleoside phosphate metabolic processGO:00067531080.043
positive regulation of developmental growthGO:00486393540.042
synapse organizationGO:0050808240.041
system processGO:00030081360.041
muscle cell developmentGO:00550011580.041
multicellular organism growthGO:00352643850.041
developmental maturationGO:0021700260.041
cell recognitionGO:0008037850.041
anatomical structure formation involved in morphogenesisGO:00486462500.040
pattern specification processGO:0007389590.040
positive regulation of transcription dna templatedGO:00458931020.040
positive regulation of secretionGO:0051047170.040
cellular protein metabolic processGO:00442672790.039
cellular protein localizationGO:0034613750.039
single organism behaviorGO:0044708830.039
striated muscle cell differentiationGO:00511461580.039
organonitrogen compound metabolic processGO:19015641510.039
cellular protein complex assemblyGO:00436231780.039
response to woundingGO:000961140.039
regulation of synaptic transmission dopaminergicGO:003222510.039
regulation of cell developmentGO:0060284490.038
neuron projection extensionGO:1990138370.038
regulation of nervous system developmentGO:0051960410.038
positive regulation of signalingGO:0023056660.038
regulation of cellular metabolic processGO:00313233050.038
hermaphrodite genitalia developmentGO:00400357340.037
regulation of ovipositionGO:0046662430.037
developmental cell growthGO:0048588390.037
body morphogenesisGO:00101716200.037
receptor mediated endocytosisGO:00068987150.037
inorganic ion transmembrane transportGO:0098660540.037
learning or memoryGO:0007611270.036
response to osmotic stressGO:0006970290.036
regulation of cell differentiationGO:0045595810.036
regulation of nucleobase containing compound metabolic processGO:00192192220.036
cellular response to stressGO:00335541620.036
regulation of axonogenesisGO:0050770240.036
regulation of nematode larval developmentGO:00610622600.035
macromolecule biosynthetic processGO:00090592500.035
embryonic morphogenesisGO:00485981520.035
protein modification processGO:00362112070.035
transcription from rna polymerase ii promoterGO:00063661490.035
gtp metabolic processGO:0046039460.034
cell divisionGO:00513012620.034
purine ribonucleotide metabolic processGO:0009150950.034
regulation of hydrolase activityGO:0051336450.034
macromolecule modificationGO:00434122180.034
positive regulation of hydrolase activityGO:0051345380.034
small molecule metabolic processGO:00442811860.034
single organism catabolic processGO:00447121290.034
regulation of nucleotide metabolic processGO:0006140370.034
regulation of catabolic processGO:0009894570.033
regulation of cell projection organizationGO:0031344380.033
regulation of multicellular organism growthGO:00400143730.033
regulation of apoptotic processGO:0042981360.033
regulation of extent of cell growthGO:0061387200.032
regulation of organelle organizationGO:00330431640.032
regulation of cell sizeGO:0008361300.032
establishment of organelle localizationGO:00516561230.032
ras protein signal transductionGO:0007265310.032
organic cyclic compound biosynthetic processGO:19013621950.032
regulation of cell cycleGO:00517261940.031
positive regulation of signal transductionGO:0009967400.031
neurological system processGO:0050877530.031
regulation of biosynthetic processGO:00098891890.031
secretion by cellGO:00329401380.031
regulation of ion transportGO:0043269390.031
cell proliferationGO:00082831160.030
positive regulation of macromolecule biosynthetic processGO:00105571090.030
purine ribonucleoside triphosphate catabolic processGO:0009207720.030
ribonucleotide catabolic processGO:0009261750.030
positive regulation of catabolic processGO:0009896380.030
regulation of localizationGO:00328791940.030
organic substance transportGO:00717021130.030
muscle contractionGO:0006936430.030
biological adhesionGO:0022610210.030
positive regulation of rna metabolic processGO:00512541030.030
biosynthetic processGO:00090583230.030
cellular component biogenesisGO:00440852970.030
oogenesisGO:00484772290.029
regulation of nucleoside metabolic processGO:0009118370.029
cellular nitrogen compound catabolic processGO:00442701190.029
nucleic acid metabolic processGO:00903042990.029
negative regulation of response to stimulusGO:0048585730.029
regulation of rna biosynthetic processGO:20011411650.028
regulation of striated muscle contractionGO:000694240.028
regulation of intracellular signal transductionGO:1902531770.028
transmembrane transportGO:00550851100.027
ribonucleoside catabolic processGO:0042454770.027
neuron projection guidanceGO:0097485820.027
rna biosynthetic processGO:00327741690.027
striated muscle myosin thick filament assemblyGO:00716881380.027
axonal fasciculationGO:0007413790.026
guanosine containing compound catabolic processGO:1901069480.026
carbohydrate derivative catabolic processGO:1901136820.026
nucleobase containing small molecule metabolic processGO:00550861150.026
regulation of cellular catabolic processGO:0031329510.026
matingGO:0007618340.026
regulation of meiotic cell cycleGO:00514451360.025
establishment of cell polarityGO:0030010460.025
intraspecies interaction between organismsGO:005170330.025
positive regulation of cell differentiationGO:004559780.025
cellular biosynthetic processGO:00442493150.025
dendrite developmentGO:0016358420.025
ribonucleoside triphosphate catabolic processGO:0009203720.025
regulation of neurogenesisGO:0050767400.025
rna metabolic processGO:00160702280.024
regulation of synapse assemblyGO:005196320.024
organonitrogen compound catabolic processGO:1901565900.024
purine containing compound metabolic processGO:0072521950.024
nucleoside catabolic processGO:0009164780.024
ribonucleoside metabolic processGO:0009119980.024
protein phosphorylationGO:0006468850.024
regulation of neurotransmitter secretionGO:0046928160.024
purine nucleoside catabolic processGO:0006152750.024
organic substance catabolic processGO:19015752940.024
macromolecule catabolic processGO:00090572020.024
response to temperature stimulusGO:0009266660.024
divalent inorganic cation transportGO:0072511170.024
purine ribonucleoside triphosphate metabolic processGO:0009205870.023
positive regulation of nucleotide catabolic processGO:0030813280.023
nucleoside triphosphate metabolic processGO:0009141870.023
organic cyclic compound catabolic processGO:19013611190.023
gonad developmentGO:00084068400.023
muscle organ morphogenesisGO:004864440.023
glycosyl compound catabolic processGO:1901658790.023
organic substance biosynthetic processGO:19015763230.023
membrane depolarizationGO:005189910.023
catabolic processGO:00090563180.023
cognitionGO:0050890270.023
transcription dna templatedGO:00063511680.023
purine nucleoside triphosphate metabolic processGO:0009144870.023
axon guidanceGO:0007411820.022
positive regulation of purine nucleotide metabolic processGO:1900544280.022
regulation of cell proliferationGO:00421271050.022
negative regulation of post embryonic developmentGO:00485812080.022
regulation of multi organism processGO:0043900690.022
gtp catabolic processGO:0006184460.022
ribonucleotide metabolic processGO:0009259990.022
regulation of cellular biosynthetic processGO:00313261890.021
negative regulation of vulval developmentGO:00400272060.021
negative regulation of nematode larval developmentGO:00610642080.021
negative regulation of cellular processGO:00485232390.021
regulation of transcription from rna polymerase ii promoterGO:00063571450.021
positive regulation of axon extensionGO:004577340.021
positive regulation of cellular biosynthetic processGO:00313281090.020
purine nucleotide catabolic processGO:0006195750.020
nucleotide catabolic processGO:0009166770.020
locomotory behaviorGO:0007626400.020
response to organic substanceGO:00100331310.020
organophosphate catabolic processGO:0046434810.020
inductive cell migrationGO:00400391450.020
purine containing compound catabolic processGO:0072523750.020
secretionGO:00469031470.020
adult behaviorGO:003053430.020
tube formationGO:003514820.020
nucleoside metabolic processGO:0009116990.020
aromatic compound biosynthetic processGO:00194381920.020
defense responseGO:00069522960.020
cation transmembrane transportGO:0098655590.020
organ morphogenesisGO:0009887670.020
regulation of lipid metabolic processGO:001921640.019
actin cytoskeleton reorganizationGO:003153240.019
purine ribonucleotide catabolic processGO:0009154750.019
myosin filament organizationGO:00310331380.019
purine ribonucleoside catabolic processGO:0046130750.019
muscle organ developmentGO:0007517260.019
male mating behaviorGO:0060179260.019
mesoderm morphogenesisGO:0048332240.019
regulation of rna metabolic processGO:00512521730.019
regulation of cell cycle processGO:00105641450.019
protein polymerizationGO:0051258260.019
regulation of organ morphogenesisGO:200002740.019
synaptic vesicle endocytosisGO:004848830.019
adult locomotory behaviorGO:000834410.018
amine metabolic processGO:0009308150.018
cellular response to chemical stimulusGO:00708871290.018
response to oxygen levelsGO:0070482220.018
nucleic acid templated transcriptionGO:00976591690.018
positive regulation of ras gtpase activityGO:0032320190.018
purine nucleoside metabolic processGO:0042278920.018
regulation of protein metabolic processGO:0051246810.018
organophosphate metabolic processGO:00196371250.018
cellular amine metabolic processGO:0044106150.018
single organism cellular localizationGO:1902580720.017
cellular macromolecule biosynthetic processGO:00346452470.017
dorsal ventral axon guidanceGO:0033563190.017
positive regulation of purine nucleotide catabolic processGO:0033123280.017
meiotic chromosome segregationGO:00451321390.017
positive regulation of gtp catabolic processGO:0033126280.017
regulation of cell divisionGO:00513021420.017
carbohydrate derivative metabolic processGO:19011351410.017
negative regulation of organelle organizationGO:0010639200.017
divalent metal ion transportGO:0070838170.017
regulation of apoptotic signaling pathwayGO:200123310.016
positive regulation of synaptic transmissionGO:0050806240.016
pharyngeal pumpingGO:0043050580.016
regulation of primary metabolic processGO:00800902920.016
muscle fiber developmentGO:004874720.016
apoptotic cell clearanceGO:00432771110.016
regulation of cellular macromolecule biosynthetic processGO:20001121880.016
oxoacid metabolic processGO:0043436470.016
multicellular organismal movementGO:005087920.016
embryonic body morphogenesisGO:0010172490.016
regulation of cellular amine metabolic processGO:003323800.016
neuromuscular junction developmentGO:000752820.016
chromosome segregationGO:00070591800.016
regulation of purine nucleotide metabolic processGO:1900542370.016
cell cycle processGO:00224024820.016
negative regulation of cellular metabolic processGO:0031324950.015
ion transportGO:00068111130.015
response to heatGO:0009408500.015
positive regulation of nervous system developmentGO:005196250.015
posttranscriptional regulation of gene expressionGO:00106081660.015
negative regulation of cell morphogenesis involved in differentiationGO:001077120.015
monovalent inorganic cation transportGO:0015672330.015
regulation of small gtpase mediated signal transductionGO:0051056410.015
positive regulation of secretion by cellGO:1903532140.015
actin filament organizationGO:0007015210.015
nucleobase containing compound biosynthetic processGO:00346541840.015
anatomical structure homeostasisGO:0060249110.015
heterocycle catabolic processGO:00467001190.015
excretionGO:0007588490.015
actin filament bundle assemblyGO:005101730.015
regulation of muscle system processGO:0090257200.015
myosin filament assemblyGO:00310341380.015
genitalia developmentGO:00488067410.015
positive regulation of nucleotide metabolic processGO:0045981280.014
social behaviorGO:003517630.014
protein catabolic processGO:00301631620.014
nucleobase containing compound catabolic processGO:00346551140.014
positive regulation of cell migrationGO:003033530.014
regulation of cellular protein metabolic processGO:0032268750.014
positive regulation of cellular catabolic processGO:0031331350.014
microtubule based processGO:00070171820.014
regulation of synaptic plasticityGO:004816710.014
meiotic cell cycle processGO:19030461700.014
regulation of epithelial cell proliferationGO:005067810.014
learningGO:0007612210.014
feeding behaviorGO:0007631700.014
regulation of cytoskeleton organizationGO:0051493410.014
regulation of cellular component biogenesisGO:0044087260.014
regulation of macromolecule biosynthetic processGO:00105561890.014
synaptic transmission cholinergicGO:0007271210.014
regulation of nucleic acid templated transcriptionGO:19035061650.014
lamellipodium organizationGO:009758120.014
negative regulation of gene expressionGO:00106292170.014
canonical wnt signaling pathwayGO:006007030.013
cell growthGO:0016049440.013
establishment of nucleus localizationGO:0040023550.013
negative regulation of locomotionGO:0040013210.013
negative regulation of neurogenesisGO:005076840.013
neuron neuron synaptic transmissionGO:0007270220.013
regulation of gtpase activityGO:0043087300.013
eating behaviorGO:0042755590.013
regulation of feeding behaviorGO:0060259380.013
response to metal ionGO:0010038330.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092120.013
phagocytosisGO:00069091150.013
hormone metabolic processGO:004244530.013
negative regulation of signalingGO:0023057610.013
metal ion transportGO:0030001490.012
vulval developmentGO:00400253330.012
memoryGO:000761330.012
protein oligomerizationGO:005125940.012
spermatogenesisGO:0007283410.012
maintenance of protein locationGO:0045185150.012
heterocycle biosynthetic processGO:00181301870.012
ion transmembrane transportGO:0034220910.012
posttranscriptional gene silencingGO:00164411430.012
cellular homeostasisGO:0019725220.012

tmc-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
musculoskeletal system diseaseDOID:1700.025
cardiomyopathyDOID:005070000.017
muscle tissue diseaseDOID:6600.017
cardiovascular system diseaseDOID:128700.017
myopathyDOID:42300.017
muscular diseaseDOID:008000000.017
heart diseaseDOID:11400.017
nervous system diseaseDOID:86300.014