Caenorhabditis elegans

147 known processes

let-526 (CELE_C01G8.9)

Protein LET-526

let-526 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism reproductive processGO:004470211960.427
post embryonic developmentGO:000979121520.344
reproductive system developmentGO:00614588500.318
organ developmentGO:004851311020.313
embryo developmentGO:000979030520.299
cellular biosynthetic processGO:00442493150.294
cell projection morphogenesisGO:00488581480.272
locomotionGO:004001116340.248
nucleic acid metabolic processGO:00903042990.241
regulation of developmental processGO:00507936840.231
protein metabolic processGO:00195384220.231
cell part morphogenesisGO:00329901520.229
negative regulation of vulval developmentGO:00400272060.229
developmental process involved in reproductionGO:000300611650.227
cell motilityGO:00488703130.225
post embryonic organ developmentGO:00485693360.216
regulation of cellular metabolic processGO:00313233050.213
cellular nitrogen compound biosynthetic processGO:00442711920.200
chemotaxisGO:00069351200.197
chromosome organizationGO:00512761040.195
Human Mouse
embryo development ending in birth or egg hatchingGO:000979229920.192
reproductive structure developmentGO:00486088500.190
gonad developmentGO:00084068400.189
multicellular organismal reproductive processGO:00486098150.180
regulation of metabolic processGO:00192224780.179
hermaphrodite genitalia developmentGO:00400357340.178
vesicle mediated transportGO:00161928520.178
transcription dna templatedGO:00063511680.177
positive regulation of cellular metabolic processGO:00313251780.177
nucleobase containing compound metabolic processGO:00061394060.176
localization of cellGO:00516743130.175
taxisGO:00423301280.175
cellular component movementGO:00069283880.171
heterocycle biosynthetic processGO:00181301870.167
gene expressionGO:00104674120.167
rna metabolic processGO:00160702280.162
negative regulation of post embryonic developmentGO:00485812080.161
transcription from rna polymerase ii promoterGO:00063661490.159
transportGO:000681010930.159
regulation of transcription from rna polymerase ii promoterGO:00063571450.159
regulation of macromolecule metabolic processGO:00602554210.158
regulation of gene expressionGO:00104683660.156
response to external stimulusGO:00096052890.155
protein modification processGO:00362112070.145
single organism signalingGO:00447004010.144
Human
vulval developmentGO:00400253330.142
neurogenesisGO:00220082360.140
positive regulation of transcription dna templatedGO:00458931020.138
cellular protein modification processGO:00064642070.133
regulation of macromolecule biosynthetic processGO:00105561890.133
cellular macromolecule biosynthetic processGO:00346452470.130
phosphate containing compound metabolic processGO:00067962320.129
regulation of nucleobase containing compound metabolic processGO:00192192220.128
receptor mediated endocytosisGO:00068987150.128
sex differentiationGO:00075489090.126
regulation of rna metabolic processGO:00512521730.126
multicellular organismal agingGO:00102598120.125
ovipositionGO:00189913640.125
neuron differentiationGO:00301822170.122
neuron developmentGO:00486661990.121
macromolecule modificationGO:00434122180.121
nucleic acid templated transcriptionGO:00976591690.121
regulation of vulval developmentGO:00400282480.119
generation of neuronsGO:00486992350.118
cell cycleGO:00070495260.117
development of primary sexual characteristicsGO:00451378400.116
negative regulation of multicellular organismal processGO:00512412360.112
regulation of nematode larval developmentGO:00610622600.110
negative regulation of biological processGO:00485195670.110
multicellular organism reproductionGO:00325048190.110
regulation of multicellular organismal developmentGO:20000263170.109
agingGO:00075688120.109
rna biosynthetic processGO:00327741690.107
cell cycle processGO:00224024820.107
cell developmentGO:00484686960.107
cell migrationGO:00164773060.105
regulation of nucleic acid templated transcriptionGO:19035061650.104
cell projection organizationGO:00300302310.102
regulation of post embryonic developmentGO:00485802600.100
positive regulation of nucleic acid templated transcriptionGO:19035081020.099
nervous system developmentGO:00073992530.097
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.097
Mouse
positive regulation of signalingGO:0023056660.096
multicellular organismal reproductive behaviorGO:00330573840.095
digestive tract developmentGO:00485651220.095
positive regulation of nitrogen compound metabolic processGO:00511731340.094
cellular component biogenesisGO:00440852970.094
canonical wnt signaling pathwayGO:006007030.094
positive regulation of signal transductionGO:0009967400.091
macromolecule localizationGO:00330367710.090
axon guidanceGO:0007411820.089
body morphogenesisGO:00101716200.087
regulation of biological qualityGO:00650087410.086
regulation of primary metabolic processGO:00800902920.086
neuron projection guidanceGO:0097485820.086
signalingGO:00230524010.085
Human
nucleobase containing compound biosynthetic processGO:00346541840.085
regulation of rna biosynthetic processGO:20011411650.084
digestive system developmentGO:00551231220.084
regulation of nitrogen compound metabolic processGO:00511712220.083
developmental growthGO:00485894120.082
multi organism behaviorGO:00517053890.082
regulation of locomotionGO:00400121610.082
negative regulation of cellular processGO:00485232390.081
Mouse
cell surface receptor signaling pathwayGO:00071661490.080
neuron projection developmentGO:00311751870.080
negative regulation of metabolic processGO:00098922400.079
Mouse
cellular protein metabolic processGO:00442672790.078
sexual reproductionGO:00199535460.078
biosynthetic processGO:00090583230.078
cellular component assemblyGO:00226072930.077
organic substance biosynthetic processGO:19015763230.075
behaviorGO:00076105270.075
positive regulation of cellular processGO:00485223320.075
regulation of cell cycleGO:00517261940.074
determination of adult lifespanGO:00083408120.074
regulation of multicellular organismal processGO:00512397260.074
defense responseGO:00069522960.074
regulation of cellular macromolecule biosynthetic processGO:20001121880.073
digestive tract morphogenesisGO:0048546760.072
positive regulation of macromolecule biosynthetic processGO:00105571090.072
oxoacid metabolic processGO:0043436470.072
response to endoplasmic reticulum stressGO:0034976710.071
immune responseGO:00069551920.071
response to chemicalGO:00422213560.070
catabolic processGO:00090563180.070
regulation of biosynthetic processGO:00098891890.070
positive regulation of rna metabolic processGO:00512541030.069
neuron projection morphogenesisGO:00488121140.068
regulation of transcription dna templatedGO:00063551640.068
negative regulation of developmental processGO:00510932270.068
maintenance of locationGO:00512355800.067
phosphorylationGO:00163101160.066
negative regulation of macromolecule metabolic processGO:00106052290.065
Mouse
multi organism reproductive processGO:00447038670.065
muscle tissue developmentGO:006053710.064
Mouse
cell morphogenesisGO:00009021630.062
cell morphogenesis involved in neuron differentiationGO:00486671110.061
aromatic compound biosynthetic processGO:00194381920.061
embryonic morphogenesisGO:00485981520.060
Mouse
organelle organizationGO:00069967830.060
Human Mouse
lipid storageGO:00199155650.060
cytoskeleton organizationGO:00070103390.060
microtubule based processGO:00070171820.059
cellular process involved in reproduction in multicellular organismGO:00224123510.059
axon developmentGO:00615641630.059
regulation of cellular biosynthetic processGO:00313261890.059
regulation of response to stimulusGO:00485832430.059
multi organism reproductive behaviorGO:00447053870.058
multi multicellular organism processGO:00447063900.058
tube developmentGO:00352951260.057
Mouse
macromolecule biosynthetic processGO:00090592500.057
lipid localizationGO:00108765730.057
reproductive behaviorGO:00190983870.056
organic substance catabolic processGO:19015752940.056
positive regulation of locomotionGO:0040017420.056
endocytosisGO:00068978190.055
tube morphogenesisGO:0035239790.055
Mouse
genitalia developmentGO:00488067410.054
protein phosphorylationGO:0006468850.054
signal transductionGO:00071653170.053
Human
establishment of localizationGO:005123411710.053
regulation of phosphate metabolic processGO:0019220810.053
organelle fissionGO:00482853630.053
positive regulation of cell communicationGO:0010647690.053
negative regulation of nematode larval developmentGO:00610642080.053
phosphorus metabolic processGO:00067932320.053
regulation of developmental growthGO:00486383890.052
organic cyclic compound biosynthetic processGO:19013621950.052
protein localizationGO:00081042050.051
positive regulation of rna biosynthetic processGO:19026801020.050
inductive cell migrationGO:00400391450.050
apoptotic processGO:00069154780.050
gamete generationGO:00072764610.050
male sex differentiationGO:0046661860.049
cell deathGO:00082195470.048
response to abiotic stimulusGO:00096281520.048
positive regulation of neurogenesisGO:005076940.048
regulation of cell communicationGO:00106461760.047
regulation of phosphorus metabolic processGO:0051174810.047
aromatic compound catabolic processGO:00194391160.047
macromolecular complex subunit organizationGO:00439333200.047
Human Mouse
germ cell developmentGO:00072813510.047
cell growthGO:0016049440.046
positive regulation of response to stimulusGO:0048584550.046
positive regulation of developmental growthGO:00486393540.046
molting cycle collagen and cuticulin based cuticleGO:00189962810.046
single organism organelle organizationGO:19025895010.044
Human
innate immune responseGO:00450871900.044
establishment of spindle localizationGO:0051293510.044
single organism transportGO:00447654470.044
positive regulation of growthGO:00459273690.044
epithelial cell proliferationGO:005067310.043
single organism localizationGO:19025785180.043
growthGO:00400075620.043
cellular component morphogenesisGO:00329893180.043
establishment or maintenance of cell polarityGO:0007163630.042
negative regulation of cellular metabolic processGO:0031324950.042
Mouse
mitotic cell cycle processGO:19030471940.041
pattern specification processGO:0007389590.041
small molecule metabolic processGO:00442811860.041
cell recognitionGO:0008037850.040
intracellular signal transductionGO:0035556960.040
negative regulation of neurogenesisGO:005076840.039
organonitrogen compound metabolic processGO:19015641510.039
response to woundingGO:000961140.039
epithelium developmentGO:0060429680.039
Mouse
positive regulation of developmental processGO:00510944080.038
positive regulation of nucleobase containing compound metabolic processGO:00459351340.038
regulation of multicellular organism growthGO:00400143730.037
regulation of signalingGO:00230511720.037
positive regulation of multicellular organismal processGO:00512404170.036
carbohydrate derivative metabolic processGO:19011351410.036
regulation of growthGO:00400084090.035
regulation of protein localizationGO:0032880500.035
establishment of cell polarityGO:0030010460.035
system processGO:00030081360.035
regulation of cytoplasmic transportGO:190364930.035
head developmentGO:006032210.035
Mouse
regulation of catalytic activityGO:0050790780.035
regulation of cellular component organizationGO:00511282480.035
small gtpase mediated signal transductionGO:0007264320.035
deathGO:00162655470.035
regulation of organelle organizationGO:00330431640.035
negative regulation of nitrogen compound metabolic processGO:0051172630.035
Mouse
heterocycle catabolic processGO:00467001190.035
negative regulation of gene expressionGO:00106292170.035
Mouse
ribonucleoside triphosphate metabolic processGO:0009199870.034
regulation of localizationGO:00328791940.034
muscle structure developmentGO:00610611910.034
Mouse
carboxylic acid metabolic processGO:0019752340.034
response to biotic stimulusGO:00096071010.033
positive regulation of multicellular organism growthGO:00400183520.033
cellular catabolic processGO:00442481990.033
negative regulation of nucleic acid templated transcriptionGO:1903507530.032
Mouse
regulation of intracellular signal transductionGO:1902531770.032
positive regulation of phosphorus metabolic processGO:0010562560.032
synaptic target recognitionGO:000803930.032
regulation of protein metabolic processGO:0051246810.032
molting cycleGO:00423032810.032
actin cytoskeleton organizationGO:00300361840.032
neuron recognitionGO:0008038830.032
positive regulation of phosphate metabolic processGO:0045937560.031
positive regulation of metabolic processGO:00098931870.031
cell divisionGO:00513012620.031
axonogenesisGO:00074091020.030
cellular nitrogen compound catabolic processGO:00442701190.030
positive regulation of macromolecule metabolic processGO:00106041490.030
protein complex subunit organizationGO:00718222800.030
Human
regulation of cellular ketone metabolic processGO:001056530.030
dna metabolic processGO:0006259740.029
regulation of cell proliferationGO:00421271050.029
regulation of cell motilityGO:2000145570.029
regulation of molecular functionGO:0065009890.029
positive regulation of catalytic activityGO:0043085590.029
cellular response to stressGO:00335541620.029
programmed cell deathGO:00125015000.029
anatomical structure formation involved in morphogenesisGO:00486462500.029
Mouse
cellular localizationGO:00516413600.029
chromatin assembly or disassemblyGO:000633310.028
Human
regulation of cell sizeGO:0008361300.028
chromatin organizationGO:0006325320.028
Human Mouse
regulation of epithelial cell proliferationGO:005067810.028
protein complex biogenesisGO:00702711860.028
multicellular organism growthGO:00352643850.027
meiotic cell cycle processGO:19030461700.027
regulation of signal transductionGO:00099661350.027
meiotic nuclear divisionGO:00071263000.027
regulation of gene expression epigeneticGO:00400291630.026
Mouse
regulation of cellular component movementGO:0051270620.026
cellular protein complex assemblyGO:00436231780.026
posttranscriptional regulation of gene expressionGO:00106081660.026
organelle assemblyGO:00709252140.026
positive regulation of molecular functionGO:0044093610.026
embryonic body morphogenesisGO:0010172490.026
negative regulation of cellular biosynthetic processGO:0031327650.025
Mouse
regulation of extent of cell growthGO:0061387200.025
organic acid metabolic processGO:0006082470.025
protein complex assemblyGO:00064611860.025
regulation of cellular component sizeGO:0032535400.025
asymmetric protein localizationGO:0008105350.025
organophosphate metabolic processGO:00196371250.025
chromosome segregationGO:00070591800.025
organophosphate catabolic processGO:0046434810.025
cell type specific apoptotic processGO:009728540.025
regulation of cellular amine metabolic processGO:003323800.025
response to other organismGO:00517071010.025
cellular component assembly involved in morphogenesisGO:00109271830.025
meiotic cell cycleGO:00513213350.025
cation transportGO:0006812780.024
tissue developmentGO:00098881120.024
Mouse
nucleobase containing compound catabolic processGO:00346551140.024
ras protein signal transductionGO:0007265310.024
regulation of neuron projection developmentGO:0010975310.024
glycosyl compound catabolic processGO:1901658790.024
protein catabolic processGO:00301631620.024
tissue morphogenesisGO:0048729650.023
Mouse
organic cyclic compound catabolic processGO:19013611190.023
positive regulation of cellular biosynthetic processGO:00313281090.023
chromatin remodelingGO:000633820.023
Human Mouse
regulation of actin filament based processGO:0032970220.023
actin filament based processGO:00300291910.023
nucleoside metabolic processGO:0009116990.023
posttranscriptional gene silencingGO:00164411430.023
skeletal muscle organ developmentGO:006053830.023
negative regulation of macromolecule biosynthetic processGO:0010558650.023
Mouse
rna interferenceGO:00162461370.022
cell proliferationGO:00082831160.022
regulation of behaviorGO:0050795970.022
ribonucleotide catabolic processGO:0009261750.022
gene silencingGO:00164581430.022
Mouse
cellular amino acid metabolic processGO:0006520150.021
cell cell signalingGO:00072671180.021
motor neuron axon guidanceGO:0008045130.021
regulation of cellular amino acid metabolic processGO:000652100.021
regulation of mitotic cell cycleGO:0007346760.021
nucleotide catabolic processGO:0009166770.021
striated muscle cell differentiationGO:00511461580.021
Mouse
purine ribonucleotide metabolic processGO:0009150950.020
cell morphogenesis involved in differentiationGO:00009041120.020
cellular ketone metabolic processGO:0042180140.020
regulation of cell cycle processGO:00105641450.020
membrane organizationGO:00610241350.019
posttranscriptional gene silencing by rnaGO:00351941430.019
sensory organ morphogenesisGO:009059620.019
Mouse
macromolecule catabolic processGO:00090572020.019
positive regulation of cell migrationGO:003033530.019
establishment of mitotic spindle localizationGO:0040001410.019
mitotic nuclear divisionGO:0007067890.019
epithelial tube morphogenesisGO:006056210.019
Mouse
positive regulation of biosynthetic processGO:00098911090.019
regulation of ovipositionGO:0046662430.018
purine nucleotide metabolic processGO:0006163950.018
response to external biotic stimulusGO:00432071010.018
regulation of cell divisionGO:00513021420.018
macromolecular complex assemblyGO:00650031930.018
dauer larval developmentGO:0040024920.018
oogenesisGO:00484772290.018
regulation of cell morphogenesisGO:0022604400.018
positive regulation of protein metabolic processGO:0051247450.018
cellular response to abiotic stimulusGO:007121440.018
positive regulation of intracellular signal transductionGO:1902533240.018
cytoskeleton dependent cytokinesisGO:0061640350.018
defense response to other organismGO:00985421000.018
regulation of axonogenesisGO:0050770240.017
nucleoside catabolic processGO:0009164780.017
regulation of reproductive processGO:2000241660.017
establishment of spindle orientationGO:0051294340.017
positive regulation of gene expressionGO:00106281120.017
regulation of sequence specific dna binding transcription factor activityGO:005109030.017
secretion by cellGO:00329401380.017
positive regulation of epithelial cell proliferationGO:005067910.017
defense response to bacteriumGO:0042742860.017
regulation of nuclear divisionGO:00517831150.017
response to organic substanceGO:00100331310.017
regulation of hydrolase activityGO:0051336450.017
regulation of nucleocytoplasmic transportGO:004682230.017
amine metabolic processGO:0009308150.017
striated muscle myosin thick filament assemblyGO:00716881380.017
single organism catabolic processGO:00447121290.017
muscle cell differentiationGO:00426921710.017
Mouse
axon extensionGO:0048675370.016
establishment of localization in cellGO:00516493180.016
regulation of axon extensionGO:0030516200.016
nucleobase containing small molecule metabolic processGO:00550861150.016
nucleoside triphosphate catabolic processGO:0009143720.016
female gamete generationGO:00072922540.016
regulation of neuron differentiationGO:0045664400.016
cellular lipid metabolic processGO:0044255400.016
lipid metabolic processGO:0006629770.016
muscle cell developmentGO:00550011580.016
negative regulation of transcription dna templatedGO:0045892530.016
Mouse
regionalizationGO:0003002310.016
negative regulation of rna metabolic processGO:0051253530.015
Mouse
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.015
regulation of neurogenesisGO:0050767400.015
wnt signaling pathwayGO:0016055270.015
male anatomical structure morphogenesisGO:0090598780.015
establishment of organelle localizationGO:00516561230.015
defense response to gram negative bacteriumGO:0050829640.015
organonitrogen compound catabolic processGO:1901565900.015
nematode male tail tip morphogenesisGO:0045138770.015
spindle localizationGO:0051653510.015
positive regulation of protein transportGO:005122240.015
cytokinesisGO:0000910800.015
gene silencing by rnaGO:00310471430.015
organ morphogenesisGO:0009887670.015
Mouse
cell adhesionGO:0007155210.015
meiotic chromosome segregationGO:00451321390.014
response to bacteriumGO:0009617860.014
single organism behaviorGO:0044708830.014
negative regulation of gene expression epigeneticGO:004581420.014
Mouse
negative regulation of neuron differentiationGO:004566540.014
ribonucleoside metabolic processGO:0009119980.014
nucleoside triphosphate metabolic processGO:0009141870.014
bmp signaling pathwayGO:003050930.014
regulation of response to woundingGO:190303410.014
positive regulation of phosphorylationGO:0042327270.014
gtp metabolic processGO:0046039460.014
neuromuscular junction developmentGO:000752820.014
regulation of cytoskeleton organizationGO:0051493410.014
synaptic transmissionGO:00072681060.014
regulation of cell deathGO:0010941650.014
cell fate commitmentGO:00451651390.014
covalent chromatin modificationGO:0016569300.013
purine containing compound metabolic processGO:0072521950.013
cellular amine metabolic processGO:0044106150.013
regulation of protein targetingGO:190353330.013
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.013
nucleotide metabolic processGO:00091171080.013
rrna processingGO:000636430.013
regulation of nervous system developmentGO:0051960410.013
regulation of cellular protein metabolic processGO:0032268750.013
purine ribonucleoside triphosphate catabolic processGO:0009207720.013
vesicle localizationGO:0051648240.013
internal peptidyl lysine acetylationGO:001839330.013
tube formationGO:003514820.013
Mouse
nucleoside phosphate catabolic processGO:1901292770.013
intracellular receptor signaling pathwayGO:003052220.013
Human
regulation of epithelial cell differentiationGO:003085640.013
purine nucleoside catabolic processGO:0006152750.013
regulation of apoptotic signaling pathwayGO:200123310.013
regulation of anatomical structure sizeGO:0090066460.013
neuron projection extensionGO:1990138370.012
axonal fasciculationGO:0007413790.012
myosin filament organizationGO:00310331380.012
metal ion transportGO:0030001490.012
endoplasmic reticulum unfolded protein responseGO:0030968660.012
negative regulation of cell cycleGO:0045786530.012
positive regulation of protein modification processGO:0031401290.012
regulation of multi organism processGO:0043900690.012
ribose phosphate metabolic processGO:0019693990.012
myofibril assemblyGO:00302391540.012
regenerationGO:003109940.012
regulation of meiotic cell cycleGO:00514451360.012
regulation of protein import into nucleusGO:004230630.012
gastrulationGO:0007369580.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.012
Mouse
purine containing compound catabolic processGO:0072523750.012
synaptic growth at neuromuscular junctionGO:005112410.012
purine ribonucleotide catabolic processGO:0009154750.012
organelle localizationGO:00516401270.012
cellular macromolecular complex assemblyGO:00346221840.011
regulation of protein modification processGO:0031399460.011
positive regulation of cell deathGO:0010942380.011
synapse organizationGO:0050808240.011
cellular response to topologically incorrect proteinGO:0035967760.011
purine ribonucleoside metabolic processGO:0046128920.011
purine ribonucleoside catabolic processGO:0046130750.011
immune response regulating signaling pathwayGO:000276410.011
regulation of cell projection organizationGO:0031344380.011
myosin filament assemblyGO:00310341380.011
negative regulation of locomotionGO:0040013210.011
peptidyl amino acid modificationGO:0018193580.011
ribonucleotide metabolic processGO:0009259990.011
negative regulation of response to external stimulusGO:003210230.011
cellular protein localizationGO:0034613750.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.011
response to osmotic stressGO:0006970290.011
purine nucleotide catabolic processGO:0006195750.010
pharynx developmentGO:0060465510.010
regulation of cell differentiationGO:0045595810.010
neuron apoptotic processGO:005140240.010
cellular response to unfolded proteinGO:0034620710.010
carbohydrate derivative catabolic processGO:1901136820.010
adult behaviorGO:003053430.010
positive regulation of cell projection organizationGO:003134640.010
cellular macromolecule localizationGO:0070727750.010
apical junction assemblyGO:004329710.010
response to oxygen containing compoundGO:1901700440.010
glycosyl compound metabolic processGO:19016571000.010
positive regulation of intracellular transportGO:003238820.010
g1 s transition of mitotic cell cycleGO:000008220.010
anatomical structure homeostasisGO:0060249110.010

let-526 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.070
cancerDOID:16200.044
organ system cancerDOID:005068600.026
disease of anatomical entityDOID:700.022
gastrointestinal system cancerDOID:311900.014
nervous system diseaseDOID:86300.010