Caenorhabditis elegans

60 known processes

knl-1 (CELE_C02F5.1)

Protein KNL-1

knl-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.958
organelle fissionGO:00482853630.931
embryo developmentGO:000979030520.890
cell cycleGO:00070495260.844
chromosome segregationGO:00070591800.784
attachment of spindle microtubules to kinetochoreGO:000860880.709
maintenance of protein location in cellGO:0032507120.651
establishment of localizationGO:005123411710.646
dna metabolic processGO:0006259740.614
single organism organelle organizationGO:19025895010.613
mitotic cell cycle processGO:19030471940.613
meiotic nuclear divisionGO:00071263000.502
chromosome organization involved in meiosisGO:0070192250.492
meiotic cell cycle processGO:19030461700.465
meiotic chromosome segregationGO:00451321390.425
attachment of mitotic spindle microtubules to kinetochoreGO:005131560.415
dna duplex unwindingGO:003250830.405
meiotic cell cycleGO:00513213350.386
regulation of mitotic metaphase anaphase transitionGO:003007150.365
spindle organizationGO:0007051920.355
single organism reproductive processGO:004470211960.319
cell cycle processGO:00224024820.299
microtubule based processGO:00070171820.294
cytoskeleton organizationGO:00070103390.284
chromosome organizationGO:00512761040.277
maintenance of location in cellGO:0051651120.267
sister chromatid segregationGO:0000819460.263
single organism localizationGO:19025785180.261
microtubule anchoringGO:003445380.244
organelle organizationGO:00069967830.241
gonad developmentGO:00084068400.230
protein localizationGO:00081042050.218
purine ribonucleotide catabolic processGO:0009154750.216
multicellular organismal reproductive processGO:00486098150.207
Worm
cell divisionGO:00513012620.199
mitotic nuclear divisionGO:0007067890.197
development of primary sexual characteristicsGO:00451378400.189
nucleotide catabolic processGO:0009166770.186
mitotic sister chromatid segregationGO:0000070380.183
purine ribonucleoside triphosphate catabolic processGO:0009207720.183
transportGO:000681010930.180
cellular response to stressGO:00335541620.173
meiosis iGO:0007127190.164
dna repairGO:0006281230.159
cellular protein localizationGO:0034613750.158
regulation of biological qualityGO:00650087410.156
sex differentiationGO:00075489090.154
protein complex subunit organizationGO:00718222800.154
hermaphrodite genitalia developmentGO:00400357340.154
carbohydrate derivative metabolic processGO:19011351410.152
regulation of cell divisionGO:00513021420.148
macromolecular complex subunit organizationGO:00439333200.147
organic substance catabolic processGO:19015752940.142
kinetochore organizationGO:005138370.140
ribonucleoside triphosphate metabolic processGO:0009199870.140
dna conformation changeGO:0071103110.139
multicellular organismal agingGO:00102598120.133
dna geometric changeGO:003239230.132
mitotic spindle organizationGO:0007052810.132
developmental process involved in reproductionGO:000300611650.128
reproductive structure developmentGO:00486088500.128
purine nucleoside metabolic processGO:0042278920.127
macromolecule localizationGO:00330367710.124
determination of adult lifespanGO:00083408120.124
endocytosisGO:00068978190.123
dna recombinationGO:0006310190.119
cellular localizationGO:00516413600.119
reproductive system developmentGO:00614588500.118
genitalia developmentGO:00488067410.115
regulation of macromolecule metabolic processGO:00602554210.115
post embryonic developmentGO:000979121520.113
Worm
growthGO:00400075620.113
Worm
cell projection morphogenesisGO:00488581480.111
aromatic compound catabolic processGO:00194391160.107
reciprocal meiotic recombinationGO:0007131110.105
double strand break repairGO:000630250.103
purine nucleoside catabolic processGO:0006152750.102
single organism catabolic processGO:00447121290.102
regulation of mitotic cell cycleGO:0007346760.099
negative regulation of biological processGO:00485195670.097
Worm
cellular component movementGO:00069283880.097
neurogenesisGO:00220082360.095
negative regulation of cell cycleGO:0045786530.094
multi organism reproductive behaviorGO:00447053870.091
Worm
cell part morphogenesisGO:00329901520.090
cellular biosynthetic processGO:00442493150.090
cell morphogenesisGO:00009021630.088
purine containing compound metabolic processGO:0072521950.087
cellular catabolic processGO:00442481990.086
response to chemicalGO:00422213560.086
chromosome condensationGO:003026160.086
positive regulation of developmental growthGO:00486393540.086
Worm
maintenance of protein locationGO:0045185150.084
response to external stimulusGO:00096052890.081
maintenance of locationGO:00512355800.080
cell developmentGO:00484686960.079
phosphorus metabolic processGO:00067932320.079
locomotionGO:004001116340.078
Worm
establishment of localization in cellGO:00516493180.077
regulation of organelle organizationGO:00330431640.077
multi organism behaviorGO:00517053890.076
Worm
phosphate containing compound metabolic processGO:00067962320.076
catabolic processGO:00090563180.075
regulation of mitosisGO:0007088180.075
polar body extrusion after meiotic divisionsGO:0040038140.074
ribonucleotide catabolic processGO:0009261750.072
purine ribonucleoside triphosphate metabolic processGO:0009205870.072
ovipositionGO:00189913640.072
Worm
purine ribonucleoside catabolic processGO:0046130750.071
organophosphate metabolic processGO:00196371250.070
cell morphogenesis involved in neuron differentiationGO:00486671110.070
organophosphate catabolic processGO:0046434810.070
neuron projection developmentGO:00311751870.069
positive regulation of mitotic sister chromatid separationGO:190197010.069
carbohydrate derivative catabolic processGO:1901136820.069
establishment of organelle localizationGO:00516561230.068
nucleoside triphosphate catabolic processGO:0009143720.068
multicellular organism reproductionGO:00325048190.065
Worm
neuron projection morphogenesisGO:00488121140.065
ribonucleoside triphosphate catabolic processGO:0009203720.065
purine containing compound catabolic processGO:0072523750.065
nucleoside metabolic processGO:0009116990.063
agingGO:00075688120.062
cytoskeleton dependent cytokinesisGO:0061640350.061
germ cell developmentGO:00072813510.061
multicellular organismal reproductive behaviorGO:00330573840.059
Worm
organ developmentGO:004851311020.059
nucleoside triphosphate metabolic processGO:0009141870.059
purine nucleoside triphosphate catabolic processGO:0009146720.059
organelle localizationGO:00516401270.058
single organism transportGO:00447654470.058
lipid storageGO:00199155650.056
negative regulation of chromosome segregationGO:005198540.055
nervous system developmentGO:00073992530.054
nucleoside phosphate catabolic processGO:1901292770.053
mitotic sister chromatid separationGO:0051306130.053
cell morphogenesis involved in differentiationGO:00009041120.052
body morphogenesisGO:00101716200.052
Worm
regulation of multicellular organismal processGO:00512397260.052
Worm
regulation of meiotic cell cycleGO:00514451360.052
ribose phosphate metabolic processGO:0019693990.052
cytokinesisGO:0000910800.051
female meiotic divisionGO:0007143170.051
cellular process involved in reproduction in multicellular organismGO:00224123510.051
ribonucleoside monophosphate metabolic processGO:0009161450.050
purine nucleotide catabolic processGO:0006195750.049
regulation of multicellular organism growthGO:00400143730.049
Worm
macromolecule biosynthetic processGO:00090592500.049
chromosome localizationGO:0050000100.048
nucleoside phosphate metabolic processGO:00067531080.048
regulation of mitotic spindle organizationGO:006023630.048
nucleobase containing small molecule metabolic processGO:00550861150.047
nucleobase containing compound catabolic processGO:00346551140.047
nucleic acid metabolic processGO:00903042990.047
glycosyl compound catabolic processGO:1901658790.047
regulation of cell cycleGO:00517261940.046
cellular nitrogen compound catabolic processGO:00442701190.046
multicellular organism growthGO:00352643850.045
Worm
regulation of chromosome organizationGO:0033044200.045
cellular response to dna damage stimulusGO:0006974410.044
purine nucleotide metabolic processGO:0006163950.044
positive regulation of chromosome segregationGO:005198410.043
cellular macromolecule localizationGO:0070727750.043
lipid localizationGO:00108765730.043
negative regulation of nucleic acid templated transcriptionGO:1903507530.043
purine nucleoside monophosphate metabolic processGO:0009126430.042
mitotic spindle stabilizationGO:004314820.041
regulation of nuclear divisionGO:00517831150.041
metaphase anaphase transition of mitotic cell cycleGO:0007091100.040
biosynthetic processGO:00090583230.040
positive regulation of multicellular organismal processGO:00512404170.040
Worm
regulation of primary metabolic processGO:00800902920.040
regulation of developmental processGO:00507936840.040
Worm
negative regulation of cellular processGO:00485232390.040
synapsisGO:0007129100.039
regulation of mitotic sister chromatid segregationGO:0033047160.039
receptor mediated endocytosisGO:00068987150.039
protein localization to organelleGO:0033365370.039
generation of neuronsGO:00486992350.038
pronuclear migrationGO:0035046510.038
centromere complex assemblyGO:003450850.038
chromatin assembly or disassemblyGO:000633310.037
positive regulation of developmental processGO:00510944080.036
Worm
cellular protein catabolic processGO:0044257370.036
sexual reproductionGO:00199535460.036
positive regulation of cellular protein catabolic processGO:190336430.035
negative regulation of gene expressionGO:00106292170.035
reproductive behaviorGO:00190983870.035
Worm
nucleotide metabolic processGO:00091171080.034
purine nucleoside triphosphate metabolic processGO:0009144870.034
purine ribonucleoside metabolic processGO:0046128920.034
multi multicellular organism processGO:00447063900.034
Worm
nucleobase containing compound biosynthetic processGO:00346541840.033
nucleoside catabolic processGO:0009164780.032
organonitrogen compound catabolic processGO:1901565900.032
membrane organizationGO:00610241350.032
neuron differentiationGO:00301822170.031
atp metabolic processGO:0046034420.031
positive regulation of signalingGO:0023056660.031
protein complex biogenesisGO:00702711860.031
aromatic compound biosynthetic processGO:00194381920.031
metaphase anaphase transition of cell cycleGO:0044784150.030
proteolysis involved in cellular protein catabolic processGO:0051603320.030
posttranscriptional regulation of gene expressionGO:00106081660.029
vesicle mediated transportGO:00161928520.029
cellular macromolecular complex assemblyGO:00346221840.028
regulation of localizationGO:00328791940.028
nucleoside monophosphate metabolic processGO:0009123460.028
organonitrogen compound metabolic processGO:19015641510.028
microtubule based movementGO:0007018330.028
inductive cell migrationGO:00400391450.027
protein catabolic processGO:00301631620.027
gene expressionGO:00104674120.027
reciprocal dna recombinationGO:0035825110.026
negative regulation of mitotic cell cycleGO:0045930420.026
positive regulation of growthGO:00459273690.026
Worm
multi organism reproductive processGO:00447038670.026
Worm
regulation of sister chromatid segregationGO:0033045160.026
metaphase plate congressionGO:005131050.025
regulation of cell cycle processGO:00105641450.025
chemotaxisGO:00069351200.025
axon developmentGO:00615641630.024
nucleobase containing compound metabolic processGO:00061394060.024
ribonucleoside metabolic processGO:0009119980.024
regulation of multicellular organismal developmentGO:20000263170.024
Worm
heterocycle catabolic processGO:00467001190.024
molting cycleGO:00423032810.024
Worm
organic cyclic compound catabolic processGO:19013611190.024
phagocytosis engulfmentGO:0006911980.024
negative regulation of mitotic sister chromatid segregationGO:003304840.023
localization of cellGO:00516743130.023
positive regulation of multicellular organism growthGO:00400183520.023
Worm
glycosyl compound metabolic processGO:19016571000.023
regulation of meiosisGO:0040020940.023
regulation of chromosome segregationGO:0051983200.023
regulation of developmental growthGO:00486383890.023
Worm
ribonucleotide metabolic processGO:0009259990.023
nucleus localizationGO:0051647550.023
meiotic cytokinesisGO:0033206150.023
protein metabolic processGO:00195384220.023
negative regulation of mitotic metaphase anaphase transitionGO:004584140.022
positive regulation of chromosome organizationGO:200125220.022
purine ribonucleoside monophosphate metabolic processGO:0009167430.022
small molecule metabolic processGO:00442811860.022
ribonucleoside catabolic processGO:0042454770.022
negative regulation of cell cycle phase transitionGO:190198860.022
neuron projection guidanceGO:0097485820.021
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243450.021
negative regulation of gene expression epigeneticGO:004581420.021
regulation of nucleocytoplasmic transportGO:004682230.021
actin filament based processGO:00300291910.021
atp catabolic processGO:0006200270.021
behaviorGO:00076105270.021
Worm
kinetochore assemblyGO:005138250.021
regulation of cellular component organizationGO:00511282480.021
positive regulation of proteasomal protein catabolic processGO:190180010.021
regulation of cytoplasmic transportGO:190364930.020
apoptotic processGO:00069154780.020
nuclear migrationGO:0007097540.020
negative regulation of developmental processGO:00510932270.020
Worm
organic substance biosynthetic processGO:19015763230.020
mitotic metaphase plate congressionGO:000708050.020
gamete generationGO:00072764610.020
establishment of chromosome localizationGO:0051303100.020
purine ribonucleotide metabolic processGO:0009150950.020
cell deathGO:00082195470.020
purine nucleoside monophosphate catabolic processGO:0009128280.020
ribonucleoside monophosphate catabolic processGO:0009158280.019
heterocycle biosynthetic processGO:00181301870.019
rna metabolic processGO:00160702280.019
negative regulation of cell cycle processGO:0010948120.019
response to heatGO:0009408500.019
chromatin assemblyGO:003149710.019
regulation of growthGO:00400084090.019
Worm
cellular protein complex assemblyGO:00436231780.019
cell migrationGO:00164773060.018
protein complex assemblyGO:00064611860.018
single organism cellular localizationGO:1902580720.018
regulation of gene expressionGO:00104683660.018
regulation of metabolic processGO:00192224780.017
response to woundingGO:000961140.017
dna packagingGO:000632370.017
axonogenesisGO:00074091020.017
positive regulation of cell cycleGO:0045787550.017
programmed cell deathGO:00125015000.017
head developmentGO:006032210.016
proteasomal protein catabolic processGO:0010498200.016
negative regulation of mitotic cell cycle phase transitionGO:190199150.016
chromatin remodelingGO:000633820.016
cellular macromolecule biosynthetic processGO:00346452470.016
regulation of gene expression epigeneticGO:00400291630.016
negative regulation of nitrogen compound metabolic processGO:0051172630.016
negative regulation of macromolecule metabolic processGO:00106052290.016
oogenesisGO:00484772290.016
cell proliferationGO:00082831160.016
phagocytosisGO:00069091150.015
regulation of locomotionGO:00400121610.015
developmental growthGO:00485894120.015
Worm
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.015
microtubule cytoskeleton organization involved in mitosisGO:1902850120.015
dna topological changeGO:000626510.015
regulation of cell proliferationGO:00421271050.015
cell motilityGO:00488703130.015
nucleus organizationGO:0006997380.015
organic substance transportGO:00717021130.015
chromosome separationGO:0051304190.014
regulation of cellular macromolecule biosynthetic processGO:20001121880.014
homeostatic processGO:0042592510.014
molting cycle collagen and cuticulin based cuticleGO:00189962810.014
Worm
regulation of protein import into nucleusGO:004230630.014
nitrogen compound transportGO:0071705490.014
defense responseGO:00069522960.014
negative regulation of metabolic processGO:00098922400.014
regulation of cytoskeleton organizationGO:0051493410.014
regulation of post embryonic developmentGO:00485802600.014
Worm
regulation of helicase activityGO:005109520.014
mitotic chromosome condensationGO:000707630.014
regulation of ribosome biogenesisGO:009006910.013
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243540.013
regulation of catabolic processGO:0009894570.013
axon guidanceGO:0007411820.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:190305210.013
ubiquitin dependent protein catabolic processGO:0006511320.013
cellular protein modification processGO:00064642070.013
single organism biosynthetic processGO:0044711910.013
regulation of nitrogen compound metabolic processGO:00511712220.013
protein deubiquitinationGO:001657920.013
meiotic chromosome separationGO:005130750.013
cellular component assemblyGO:00226072930.013
cell substrate adhesionGO:003158910.012
protein oligomerizationGO:005125940.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145100.012
g1 s transition of mitotic cell cycleGO:000008220.012
regulation of nucleobase containing compound metabolic processGO:00192192220.012
rna biosynthetic processGO:00327741690.012
organelle assemblyGO:00709252140.012
deathGO:00162655470.012
regulation of protein localizationGO:0032880500.012
regulation of protein stabilityGO:003164730.011
negative regulation of nucleobase containing compound metabolic processGO:0045934630.011
synaptonemal complex assemblyGO:000713060.011
membrane invaginationGO:0010324980.011
developmental maturationGO:0021700260.011
digestive system developmentGO:00551231220.011
establishment of protein localizationGO:0045184500.011
regulation of protein targetingGO:190353330.011
regulation of signalingGO:00230511720.011
positive regulation of nucleic acid templated transcriptionGO:19035081020.011
positive regulation of cellular processGO:00485223320.011
macromolecule catabolic processGO:00090572020.011
response to inorganic substanceGO:0010035500.011
negative regulation of proteasomal protein catabolic processGO:190179940.011
posttranscriptional gene silencing by rnaGO:00351941430.011
epithelial tube morphogenesisGO:006056210.011
establishment of nucleus localizationGO:0040023550.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.010
macromolecule modificationGO:00434122180.010
rna interferenceGO:00162461370.010
establishment or maintenance of cell polarityGO:0007163630.010
purine ribonucleoside monophosphate catabolic processGO:0009169280.010
anatomical structure formation involved in morphogenesisGO:00486462500.010
secretion by cellGO:00329401380.010
cellular component morphogenesisGO:00329893180.010

knl-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.010