Caenorhabditis elegans

7 known processes

fln-2 (CELE_C23F12.1)

Protein FLN-2

fln-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.823
Worm
embryo development ending in birth or egg hatchingGO:000979229920.773
Worm
regulation of developmental processGO:00507936840.687
response to chemicalGO:00422213560.687
locomotionGO:004001116340.642
epithelium developmentGO:0060429680.531
Fly
regulation of multicellular organismal processGO:00512397260.516
organ developmentGO:004851311020.505
Worm
signalingGO:00230524010.477
post embryonic developmentGO:000979121520.458
cellular component morphogenesisGO:00329893180.447
chemotaxisGO:00069351200.444
nervous system developmentGO:00073992530.439
signal transductionGO:00071653170.435
cell projection morphogenesisGO:00488581480.428
protein metabolic processGO:00195384220.428
positive regulation of multicellular organismal processGO:00512404170.422
single organism localizationGO:19025785180.405
regulation of multicellular organismal developmentGO:20000263170.392
generation of neuronsGO:00486992350.390
taxisGO:00423301280.377
nucleobase containing compound catabolic processGO:00346551140.349
behaviorGO:00076105270.348
single organism signalingGO:00447004010.344
cell developmentGO:00484686960.343
multicellular organismal agingGO:00102598120.340
growthGO:00400075620.331
nucleobase containing compound metabolic processGO:00061394060.323
molting cycle collagen and cuticulin based cuticleGO:00189962810.306
vesicle mediated transportGO:00161928520.290
neurogenesisGO:00220082360.279
gene expressionGO:00104674120.259
receptor mediated endocytosisGO:00068987150.250
single organism reproductive processGO:004470211960.249
Worm
multicellular organismal reproductive processGO:00486098150.249
Worm
purine nucleoside triphosphate catabolic processGO:0009146720.248
cell cycleGO:00070495260.243
Worm
head developmentGO:006032210.240
neuron differentiationGO:00301822170.238
embryonic morphogenesisGO:00485981520.234
endocytosisGO:00068978190.229
neuron projection guidanceGO:0097485820.229
nucleic acid templated transcriptionGO:00976591690.228
cytoskeleton organizationGO:00070103390.228
Worm
regulation of response to stimulusGO:00485832430.227
cell morphogenesisGO:00009021630.220
cell motilityGO:00488703130.218
positive regulation of cellular processGO:00485223320.216
phosphorus metabolic processGO:00067932320.215
regulation of macromolecule metabolic processGO:00602554210.212
neuron projection developmentGO:00311751870.212
cell part morphogenesisGO:00329901520.210
organelle organizationGO:00069967830.209
Worm
body morphogenesisGO:00101716200.209
Worm
neuron developmentGO:00486661990.208
developmental growthGO:00485894120.206
regulation of biological qualityGO:00650087410.204
cellular component movementGO:00069283880.199
biosynthetic processGO:00090583230.195
negative regulation of biological processGO:00485195670.193
cell migrationGO:00164773060.190
tube morphogenesisGO:0035239790.189
deathGO:00162655470.185
cellular response to organic substanceGO:00713101190.185
axon guidanceGO:0007411820.184
cellular component biogenesisGO:00440852970.182
cell projection organizationGO:00300302310.181
phosphate containing compound metabolic processGO:00067962320.181
catabolic processGO:00090563180.180
calcium mediated signalingGO:001972230.178
establishment of localizationGO:005123411710.178
cellular response to chemical stimulusGO:00708871290.177
regulation of developmental growthGO:00486383890.176
response to external stimulusGO:00096052890.175
Fly
positive regulation of developmental processGO:00510944080.174
axon developmentGO:00615641630.172
intracellular signal transductionGO:0035556960.170
macromolecule localizationGO:00330367710.168
positive regulation of growthGO:00459273690.165
multicellular organism growthGO:00352643850.164
small molecule metabolic processGO:00442811860.164
protein complex subunit organizationGO:00718222800.163
Worm
localization of cellGO:00516743130.162
agingGO:00075688120.161
organic cyclic compound biosynthetic processGO:19013621950.160
cellular component assemblyGO:00226072930.159
heterocycle biosynthetic processGO:00181301870.157
single organism transportGO:00447654470.155
gastrulationGO:0007369580.154
organic substance biosynthetic processGO:19015763230.153
cellular nitrogen compound biosynthetic processGO:00442711920.146
apical junction assemblyGO:004329710.144
cell surface receptor signaling pathwayGO:00071661490.141
sexual reproductionGO:00199535460.141
Worm
synaptic transmissionGO:00072681060.139
positive regulation of multicellular organism growthGO:00400183520.134
regulation of primary metabolic processGO:00800902920.133
purine nucleotide metabolic processGO:0006163950.132
regulation of catalytic activityGO:0050790780.129
regulation of multicellular organism growthGO:00400143730.129
aromatic compound biosynthetic processGO:00194381920.127
organic substance catabolic processGO:19015752940.126
cellular localizationGO:00516413600.126
single organism catabolic processGO:00447121290.122
digestive tract developmentGO:00485651220.121
axonogenesisGO:00074091020.119
embryonic body morphogenesisGO:0010172490.118
inductive cell migrationGO:00400391450.118
macromolecule biosynthetic processGO:00090592500.117
regulation of phosphorus metabolic processGO:0051174810.114
programmed cell deathGO:00125015000.114
negative regulation of cellular processGO:00485232390.112
digestive tract morphogenesisGO:0048546760.111
anatomical structure formation involved in morphogenesisGO:00486462500.111
organophosphate metabolic processGO:00196371250.111
cell morphogenesis involved in differentiationGO:00009041120.111
cell divisionGO:00513012620.110
transportGO:000681010930.109
nucleoside metabolic processGO:0009116990.109
negative regulation of metabolic processGO:00098922400.109
muscle cell developmentGO:00550011580.108
nucleobase containing small molecule metabolic processGO:00550861150.107
organic cyclic compound catabolic processGO:19013611190.106
determination of adult lifespanGO:00083408120.106
regulation of phosphate metabolic processGO:0019220810.106
purine ribonucleoside triphosphate catabolic processGO:0009207720.106
nucleic acid metabolic processGO:00903042990.104
cell cycle processGO:00224024820.103
negative regulation of nematode larval developmentGO:00610642080.103
cell morphogenesis involved in neuron differentiationGO:00486671110.103
regulation of nucleobase containing compound metabolic processGO:00192192220.102
positive regulation of developmental growthGO:00486393540.102
regulation of metabolic processGO:00192224780.101
protein modification processGO:00362112070.101
system processGO:00030081360.101
heterocycle catabolic processGO:00467001190.099
regulation of rna biosynthetic processGO:20011411650.098
multicellular organism reproductionGO:00325048190.097
Worm
rna metabolic processGO:00160702280.096
regulation of gene expressionGO:00104683660.096
reproductive structure developmentGO:00486088500.095
Worm
organonitrogen compound metabolic processGO:19015641510.094
regulation of cellular metabolic processGO:00313233050.094
establishment of protein localization to membraneGO:009015030.094
apoptotic processGO:00069154780.092
nucleoside catabolic processGO:0009164780.092
negative regulation of gene expressionGO:00106292170.091
cellular nitrogen compound catabolic processGO:00442701190.091
ovulationGO:0030728330.091
Worm
ribose phosphate metabolic processGO:0019693990.090
muscle cell differentiationGO:00426921710.089
response to organic substanceGO:00100331310.087
purine ribonucleoside triphosphate metabolic processGO:0009205870.085
cellular protein metabolic processGO:00442672790.085
cellular catabolic processGO:00442481990.085
purine nucleoside triphosphate metabolic processGO:0009144870.083
nucleobase containing compound biosynthetic processGO:00346541840.083
developmental process involved in reproductionGO:000300611650.083
Worm
maintenance of locationGO:00512355800.082
single organism organelle organizationGO:19025895010.082
Worm
organelle localizationGO:00516401270.080
multicellular organismal movementGO:005087920.079
regulation of growthGO:00400084090.078
neuron projection morphogenesisGO:00488121140.078
regulation of localizationGO:00328791940.078
secretionGO:00469031470.078
oxoacid metabolic processGO:0043436470.078
cellular macromolecule biosynthetic processGO:00346452470.077
meiotic cell cycleGO:00513213350.074
Worm
positive regulation of cellular metabolic processGO:00313251780.074
tube developmentGO:00352951260.074
positive regulation of locomotionGO:0040017420.074
purine nucleoside monophosphate metabolic processGO:0009126430.073
negative regulation of developmental processGO:00510932270.071
nucleotide metabolic processGO:00091171080.071
organonitrogen compound catabolic processGO:1901565900.070
regulation of locomotionGO:00400121610.070
microtubule based movementGO:0007018330.070
cellular response to stressGO:00335541620.069
microtubule based processGO:00070171820.069
lipid storageGO:00199155650.068
lipid localizationGO:00108765730.068
ribonucleoside triphosphate metabolic processGO:0009199870.067
cellular biosynthetic processGO:00442493150.066
ribonucleoside metabolic processGO:0009119980.064
purine nucleoside metabolic processGO:0042278920.064
aromatic compound catabolic processGO:00194391160.063
nucleoside triphosphate metabolic processGO:0009141870.063
purine nucleoside monophosphate catabolic processGO:0009128280.062
regulation of cellular component organizationGO:00511282480.061
purine containing compound metabolic processGO:0072521950.061
multi organism reproductive processGO:00447038670.060
Worm
multicellular organismal reproductive behaviorGO:00330573840.060
establishment of localization in cellGO:00516493180.060
negative regulation of cellular metabolic processGO:0031324950.059
negative regulation of post embryonic developmentGO:00485812080.059
tissue morphogenesisGO:0048729650.059
Fly
regulation of intracellular signal transductionGO:1902531770.058
positive regulation of nucleobase containing compound metabolic processGO:00459351340.058
striated muscle cell differentiationGO:00511461580.058
protein complex biogenesisGO:00702711860.058
establishment of nucleus localizationGO:0040023550.057
epithelial tube morphogenesisGO:006056210.057
fertilizationGO:0009566630.057
ion transmembrane transportGO:0034220910.056
ovipositionGO:00189913640.056
macromolecular complex assemblyGO:00650031930.055
single organism behaviorGO:0044708830.055
macromolecule modificationGO:00434122180.055
anion transportGO:0006820300.055
purine containing compound catabolic processGO:0072523750.054
cellular component assembly involved in morphogenesisGO:00109271830.054
nucleoside phosphate metabolic processGO:00067531080.053
cellular macromolecular complex assemblyGO:00346221840.052
transcription dna templatedGO:00063511680.052
ribonucleotide metabolic processGO:0009259990.052
glycosyl compound metabolic processGO:19016571000.052
striated muscle cell developmentGO:00550021570.051
protein complex assemblyGO:00064611860.051
glycosyl compound catabolic processGO:1901658790.051
rna biosynthetic processGO:00327741690.051
regulation of transcription from rna polymerase ii promoterGO:00063571450.050
cell deathGO:00082195470.050
protein localizationGO:00081042050.050
positive regulation of rna biosynthetic processGO:19026801020.050
regulation of nitrogen compound metabolic processGO:00511712220.049
negative regulation of macromolecule metabolic processGO:00106052290.049
regulation of organelle organizationGO:00330431640.049
regulation of response to woundingGO:190303410.048
response to topologically incorrect proteinGO:0035966820.048
macromolecule catabolic processGO:00090572020.047
posttranscriptional regulation of gene expressionGO:00106081660.047
regulation of signalingGO:00230511720.047
genitalia developmentGO:00488067410.046
purine nucleoside catabolic processGO:0006152750.045
multi organism reproductive behaviorGO:00447053870.045
mitotic cell cycle processGO:19030471940.045
regulation of signal transductionGO:00099661350.045
extracellular matrix organizationGO:003019860.045
organ morphogenesisGO:0009887670.045
Worm
macromolecular complex subunit organizationGO:00439333200.044
Worm
regulation of molecular functionGO:0065009890.044
nucleotide catabolic processGO:0009166770.044
cellular response to unfolded proteinGO:0034620710.044
regulation of cell communicationGO:00106461760.044
positive regulation of macromolecule metabolic processGO:00106041490.044
regulation of macromolecule biosynthetic processGO:00105561890.043
regulation of biosynthetic processGO:00098891890.043
enzyme linked receptor protein signaling pathwayGO:0007167500.043
organic acid metabolic processGO:0006082470.043
cytokinesisGO:0000910800.042
regulation of mapk cascadeGO:0043408230.042
atp metabolic processGO:0046034420.042
anatomical structure homeostasisGO:0060249110.042
multi multicellular organism processGO:00447063900.041
multi organism behaviorGO:00517053890.041
collagen and cuticulin based cuticle developmentGO:0040002990.041
purine ribonucleoside catabolic processGO:0046130750.041
actomyosin structure organizationGO:00310321540.041
myosin filament assemblyGO:00310341380.041
negative regulation of multicellular organismal processGO:00512412360.040
regulation of cellular protein metabolic processGO:0032268750.040
negative regulation of gene expression epigeneticGO:004581420.040
regulation of cellular biosynthetic processGO:00313261890.040
atp catabolic processGO:0006200270.039
meiotic nuclear divisionGO:00071263000.038
Worm
tissue developmentGO:00098881120.038
Fly
post embryonic organ developmentGO:00485693360.038
response to acid chemicalGO:000110140.037
purine nucleotide catabolic processGO:0006195750.036
actin cytoskeleton organizationGO:00300361840.036
Worm
phosphorylationGO:00163101160.036
striated muscle myosin thick filament assemblyGO:00716881380.036
ion transportGO:00068111130.036
purine ribonucleoside metabolic processGO:0046128920.035
cellular protein modification processGO:00064642070.035
negative regulation of vulval developmentGO:00400272060.035
digestive system developmentGO:00551231220.035
reproductive system developmentGO:00614588500.035
Worm
cell proliferationGO:00082831160.035
regulation of gene expression epigeneticGO:00400291630.035
negative regulation of nucleobase containing compound metabolic processGO:0045934630.034
regulation of anatomical structure morphogenesisGO:0022603510.034
positive regulation of gtpase activityGO:0043547280.034
cell recognitionGO:0008037850.033
microvillus assemblyGO:003003310.033
striated muscle contractionGO:0006941170.033
gamete generationGO:00072764610.033
Worm
reproductive behaviorGO:00190983870.032
extracellular structure organizationGO:004306270.032
myosin filament organizationGO:00310331380.032
lipid metabolic processGO:0006629770.032
ras protein signal transductionGO:0007265310.032
nucleus localizationGO:0051647550.031
transcription from rna polymerase ii promoterGO:00063661490.031
nuclear migrationGO:0007097540.031
carboxylic acid catabolic processGO:004639530.031
regulation of cell motilityGO:2000145570.030
regulation of cellular macromolecule biosynthetic processGO:20001121880.030
organelle assemblyGO:00709252140.030
vulval developmentGO:00400253330.030
response to unfolded proteinGO:0006986710.029
regulation of nucleotide metabolic processGO:0006140370.029
regulation of hydrolase activityGO:0051336450.029
organic hydroxy compound metabolic processGO:1901615250.029
maintenance of location in cellGO:0051651120.029
establishment of organelle localizationGO:00516561230.028
organophosphate catabolic processGO:0046434810.028
molting cycleGO:00423032810.028
regulation of rna metabolic processGO:00512521730.028
nucleoside triphosphate catabolic processGO:0009143720.027
muscle structure developmentGO:00610611910.027
skeletal muscle organ developmentGO:006053830.027
negative regulation of nitrogen compound metabolic processGO:0051172630.026
cellular protein localizationGO:0034613750.026
response to woundingGO:000961140.026
positive regulation of metabolic processGO:00098931870.026
carboxylic acid metabolic processGO:0019752340.026
defense responseGO:00069522960.025
purine ribonucleotide catabolic processGO:0009154750.025
carbohydrate derivative catabolic processGO:1901136820.025
ribonucleoside monophosphate metabolic processGO:0009161450.025
ribonucleotide catabolic processGO:0009261750.025
meiotic cell cycle processGO:19030461700.025
nucleoside phosphate catabolic processGO:1901292770.025
homeostatic processGO:0042592510.025
sex differentiationGO:00075489090.025
secretion by cellGO:00329401380.024
muscle attachmentGO:001620330.024
lamellipodium organizationGO:009758120.024
cell substrate adhesionGO:003158910.024
neuromuscular processGO:005090510.024
protein phosphorylationGO:0006468850.024
regulation of cell cycle processGO:00105641450.024
regulation of system processGO:0044057270.024
purine ribonucleotide metabolic processGO:0009150950.024
cellular macromolecule localizationGO:0070727750.024
protein catabolic processGO:00301631620.024
regulation of cell morphogenesisGO:0022604400.024
ribonucleoside catabolic processGO:0042454770.023
sodium ion transmembrane transportGO:003572580.023
axonal fasciculationGO:0007413790.023
regulation of transcription dna templatedGO:00063551640.023
purine ribonucleoside monophosphate metabolic processGO:0009167430.023
regulation of response to stressGO:0080134280.023
carboxylic acid transportGO:0046942150.023
maintenance of protein locationGO:0045185150.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.022
regulation of cell developmentGO:0060284490.022
positive regulation of nitrogen compound metabolic processGO:00511731340.022
positive regulation of macromolecule biosynthetic processGO:00105571090.022
spicule insertionGO:003460920.022
regulation of ion transportGO:0043269390.021
actin filament based movementGO:003004840.021
cellular protein complex assemblyGO:00436231780.021
positive regulation of rna metabolic processGO:00512541030.021
maintenance of protein location in cellGO:0032507120.021
cation homeostasisGO:0055080200.021
gonad developmentGO:00084068400.020
hermaphrodite genitalia developmentGO:00400357340.020
neurological system processGO:0050877530.020
regulation of purine nucleotide metabolic processGO:1900542370.020
chemosensory behaviorGO:0007635330.020
negative regulation of signal transductionGO:0009968600.020
negative regulation of signalingGO:0023057610.020
carbohydrate derivative metabolic processGO:19011351410.020
regulation of cell migrationGO:0030334550.020
regulation of cellular catabolic processGO:0031329510.020
cuticle developmentGO:00423351000.020
membrane organizationGO:00610241350.020
mitotic nuclear divisionGO:0007067890.020
development of primary sexual characteristicsGO:00451378400.020
gene silencingGO:00164581430.020
ion homeostasisGO:0050801210.020
myofibril assemblyGO:00302391540.020
sensory organ morphogenesisGO:009059620.019
ribonucleoside triphosphate catabolic processGO:0009203720.019
regulation of cell projection assemblyGO:006049130.019
dendrite developmentGO:0016358420.019
regulation of cell differentiationGO:0045595810.019
regulation of cell deathGO:0010941650.019
cytosolic calcium ion homeostasisGO:005148020.019
chromosome organizationGO:00512761040.019
locomotory behaviorGO:0007626400.019
bmp signaling pathwayGO:003050930.019
regulation of catabolic processGO:0009894570.019
regulation of synaptic plasticityGO:004816710.019
chromosome segregationGO:00070591800.019
regulation of nucleic acid templated transcriptionGO:19035061650.019
muscle contractionGO:0006936430.019
regulation of transportGO:0051049910.019
actin mediated cell contractionGO:007025230.019
cellular homeostasisGO:0019725220.018
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.018
dna metabolic processGO:0006259740.018
regulation of cell proliferationGO:00421271050.018
cation transportGO:0006812780.018
regulation of vulval developmentGO:00400282480.018
nucleoside monophosphate metabolic processGO:0009123460.018
regulation of purine nucleotide catabolic processGO:0033121350.018
cellular response to topologically incorrect proteinGO:0035967760.018
regulation of nematode larval developmentGO:00610622600.018
positive regulation of cysteine type endopeptidase activityGO:200105630.017
positive regulation of biosynthetic processGO:00098911090.017
cell cell junction assemblyGO:000704320.017
response to abiotic stimulusGO:00096281520.017
Fly
somatic muscle developmentGO:000752510.017
chemical homeostasisGO:0048878290.017
organonitrogen compound biosynthetic processGO:1901566440.017
phagocytosisGO:00069091150.017
protein oligomerizationGO:005125940.017
actin filament based processGO:00300291910.017
Worm
negative regulation of rna metabolic processGO:0051253530.017
negative regulation of neuron differentiationGO:004566540.017
positive regulation of nucleotide catabolic processGO:0030813280.017
endoplasmic reticulum unfolded protein responseGO:0030968660.016
positive regulation of phosphorus metabolic processGO:0010562560.016
cytoskeleton dependent cytokinesisGO:0061640350.016
cell projection assemblyGO:0030031350.016
organelle fissionGO:00482853630.016
Worm
regulation of protein serine threonine kinase activityGO:0071900180.016
regulation of actin cytoskeleton organizationGO:0032956170.016
positive regulation of molecular functionGO:0044093610.016
transmembrane transportGO:00550851100.016
regulation of nucleotide catabolic processGO:0030811350.016
female gamete generationGO:00072922540.016
Worm
regulation of cell projection organizationGO:0031344380.016
regulation of phosphorylationGO:0042325450.015
positive regulation of catalytic activityGO:0043085590.015
actin cytoskeleton reorganizationGO:003153240.015
erbb signaling pathwayGO:003812790.015
cellular process involved in reproduction in multicellular organismGO:00224123510.015
oocyte constructionGO:000730820.015
cilium assemblyGO:0042384280.015
response to oxygen containing compoundGO:1901700440.015
regulation of kinase activityGO:0043549290.014
translationGO:0006412370.014
germ cell developmentGO:00072813510.014
synaptic growth at neuromuscular junctionGO:005112410.014
regulation of protein metabolic processGO:0051246810.014
regulation of transferase activityGO:0051338310.014
response to oxidative stressGO:0006979420.014
developmental growth involved in morphogenesisGO:0060560370.014
negative regulation of cellular biosynthetic processGO:0031327650.014
response to temperature stimulusGO:0009266660.014
metal ion transportGO:0030001490.013
ribosome biogenesisGO:004225440.013
detection of external stimulusGO:000958140.013
negative regulation of biosynthetic processGO:0009890650.013
regulation of apoptotic signaling pathwayGO:200123310.013
single organism biosynthetic processGO:0044711910.013
negative regulation of response to stimulusGO:0048585730.013
posttranscriptional gene silencing by rnaGO:00351941430.013
response to extracellular stimulusGO:0009991380.013
cofactor biosynthetic processGO:005118880.013
positive regulation of transportGO:0051050320.013
positive regulation of nucleic acid templated transcriptionGO:19035081020.013
cellular amino acid metabolic processGO:0006520150.013
regulation of cellular component movementGO:0051270620.013
cell cell signalingGO:00072671180.013
spindle organizationGO:0007051920.013
positive regulation of gene expressionGO:00106281120.013
small gtpase mediated signal transductionGO:0007264320.013
adult locomotory behaviorGO:000834410.013
negative regulation of cytosolic calcium ion concentrationGO:005148110.012
regulation of nervous system developmentGO:0051960410.012
negative regulation of cellular component organizationGO:0051129330.012
regulation of protein kinase activityGO:0045859280.012
regulation of embryonic cell shapeGO:001647630.012
spindle localizationGO:0051653510.012
regulation of cellular ketone metabolic processGO:001056530.012
skeletal muscle thin filament assemblyGO:003024030.012
establishment of synaptic vesicle localizationGO:0097480210.012
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.012
synaptic vesicle endocytosisGO:004848830.012
eating behaviorGO:0042755590.012
response to nutrient levelsGO:0031667350.012
positive regulation of nucleoside metabolic processGO:0045979280.012
exocytosisGO:0006887150.012
purine ribonucleoside monophosphate catabolic processGO:0009169280.012
regulation of nucleoside metabolic processGO:0009118370.012

fln-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart diseaseDOID:11400.280
muscle tissue diseaseDOID:6600.280
muscular diseaseDOID:008000000.280
disease of anatomical entityDOID:700.280
cardiomyopathyDOID:005070000.280
musculoskeletal system diseaseDOID:1700.280
cardiovascular system diseaseDOID:128700.280
myopathyDOID:42300.280
nervous system diseaseDOID:86300.058
dilated cardiomyopathyDOID:1293000.033
intrinsic cardiomyopathyDOID:006003600.033
hypertrophic cardiomyopathyDOID:1198400.019
progeriaDOID:391100.014