Caenorhabditis elegans

73 known processes

kle-2 (CELE_C29E4.2)

Protein KLE-2

kle-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.931
embryo development ending in birth or egg hatchingGO:000979229920.930
deathGO:00162655470.908
sex differentiationGO:00075489090.883
organ developmentGO:004851311020.879
organelle organizationGO:00069967830.855
organelle fissionGO:00482853630.850
reproductive system developmentGO:00614588500.823
reproductive structure developmentGO:00486088500.810
single organism reproductive processGO:004470211960.796
locomotionGO:004001116340.790
apoptotic processGO:00069154780.766
gonad developmentGO:00084068400.760
negative regulation of biological processGO:00485195670.744
cell cycleGO:00070495260.741
developmental process involved in reproductionGO:000300611650.709
regulation of macromolecule metabolic processGO:00602554210.661
single organism organelle organizationGO:19025895010.642
meiotic cell cycleGO:00513213350.620
cell deathGO:00082195470.606
multicellular organismal reproductive processGO:00486098150.551
multicellular organism reproductionGO:00325048190.536
rna metabolic processGO:00160702280.521
sexual reproductionGO:00199535460.492
post embryonic developmentGO:000979121520.489
development of primary sexual characteristicsGO:00451378400.479
protein metabolic processGO:00195384220.450
programmed cell deathGO:00125015000.449
regulation of organelle organizationGO:00330431640.449
cell developmentGO:00484686960.427
meiotic nuclear divisionGO:00071263000.425
protein complex subunit organizationGO:00718222800.420
regulation of vulval developmentGO:00400282480.412
negative regulation of metabolic processGO:00098922400.412
cellular protein metabolic processGO:00442672790.401
mitotic cell cycle processGO:19030471940.396
cellular protein modification processGO:00064642070.385
hermaphrodite genitalia developmentGO:00400357340.383
signal transductionGO:00071653170.361
protein modification processGO:00362112070.353
vulval developmentGO:00400253330.350
response to external stimulusGO:00096052890.339
macromolecule modificationGO:00434122180.329
genitalia developmentGO:00488067410.329
signalingGO:00230524010.327
chromosome organizationGO:00512761040.324
regulation of developmental processGO:00507936840.322
regulation of nematode larval developmentGO:00610622600.320
negative regulation of cellular processGO:00485232390.312
macromolecular complex subunit organizationGO:00439333200.294
regulation of primary metabolic processGO:00800902920.287
ovipositionGO:00189913640.279
regulation of gene expression epigeneticGO:00400291630.271
gamete generationGO:00072764610.271
regulation of metabolic processGO:00192224780.271
gene expressionGO:00104674120.267
single organism localizationGO:19025785180.265
cytoskeleton organizationGO:00070103390.263
nervous system developmentGO:00073992530.261
germ cell developmentGO:00072813510.261
heterocycle biosynthetic processGO:00181301870.248
cell surface receptor signaling pathwayGO:00071661490.242
regulation of mitotic cell cycleGO:0007346760.235
positive regulation of macromolecule metabolic processGO:00106041490.235
regulation of cellular component organizationGO:00511282480.234
positive regulation of multicellular organismal processGO:00512404170.229
cellular component biogenesisGO:00440852970.226
cellular component assemblyGO:00226072930.223
neurogenesisGO:00220082360.218
regulation of cellular metabolic processGO:00313233050.217
mitotic nuclear divisionGO:0007067890.216
negative regulation of multicellular organismal processGO:00512412360.211
nucleobase containing compound metabolic processGO:00061394060.210
chromatin assembly or disassemblyGO:000633310.209
cellular macromolecule biosynthetic processGO:00346452470.207
chromatin modificationGO:0016568320.203
multi organism reproductive processGO:00447038670.196
cellular process involved in reproduction in multicellular organismGO:00224123510.195
negative regulation of macromolecule metabolic processGO:00106052290.194
regulation of multicellular organismal processGO:00512397260.194
cellular localizationGO:00516413600.193
protein complex biogenesisGO:00702711860.190
cell cycle processGO:00224024820.190
regulation of nucleic acid templated transcriptionGO:19035061650.188
single organism transportGO:00447654470.182
meiotic chromosome segregationGO:00451321390.179
cell projection organizationGO:00300302310.179
negative regulation of gene expressionGO:00106292170.179
regulation of cell cycle processGO:00105641450.175
cell motilityGO:00488703130.173
multicellular organismal agingGO:00102598120.169
regulation of cell cycleGO:00517261940.168
regulation of rna metabolic processGO:00512521730.167
chromosome segregationGO:00070591800.167
biosynthetic processGO:00090583230.166
protein complex assemblyGO:00064611860.164
single organism signalingGO:00447004010.164
nucleic acid templated transcriptionGO:00976591690.163
negative regulation of nematode larval developmentGO:00610642080.160
nucleic acid metabolic processGO:00903042990.159
aromatic compound biosynthetic processGO:00194381920.157
regulation of gene expressionGO:00104683660.156
regulation of biological qualityGO:00650087410.153
proteolysisGO:0006508610.149
meiotic cell cycle processGO:19030461700.148
chromatin organizationGO:0006325320.148
macromolecular complex assemblyGO:00650031930.146
determination of adult lifespanGO:00083408120.145
muscle structure developmentGO:00610611910.145
actin filament based processGO:00300291910.143
regulation of transcription dna templatedGO:00063551640.143
agingGO:00075688120.140
macromolecule localizationGO:00330367710.137
neuron projection developmentGO:00311751870.137
positive regulation of cellular processGO:00485223320.137
head developmentGO:006032210.136
negative regulation of vulval developmentGO:00400272060.136
negative regulation of developmental processGO:00510932270.136
neuron developmentGO:00486661990.135
cellular macromolecular complex assemblyGO:00346221840.132
positive regulation of developmental processGO:00510944080.128
regulation of cell divisionGO:00513021420.127
cellular response to stressGO:00335541620.125
gene silencingGO:00164581430.125
cellular protein complex assemblyGO:00436231780.124
organic substance catabolic processGO:19015752940.123
multicellular organismal reproductive behaviorGO:00330573840.123
reproductive behaviorGO:00190983870.123
covalent chromatin modificationGO:0016569300.122
microtubule based processGO:00070171820.122
regulation of post embryonic developmentGO:00485802600.121
ubiquitin dependent protein catabolic processGO:0006511320.117
endocytosisGO:00068978190.117
regulation of nucleobase containing compound metabolic processGO:00192192220.116
single organism catabolic processGO:00447121290.115
cell migrationGO:00164773060.113
immune responseGO:00069551920.113
transportGO:000681010930.110
regulation of molecular functionGO:0065009890.109
regulation of rna biosynthetic processGO:20011411650.108
regulation of cellular biosynthetic processGO:00313261890.106
muscle cell differentiationGO:00426921710.105
post embryonic organ developmentGO:00485693360.104
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.103
regulation of mitosisGO:0007088180.103
histone modificationGO:0016570300.103
multicellular organism growthGO:00352643850.102
developmental growthGO:00485894120.102
mitotic spindle organizationGO:0007052810.102
nucleobase containing compound biosynthetic processGO:00346541840.101
tube developmentGO:00352951260.101
growthGO:00400075620.101
oogenesisGO:00484772290.100
negative regulation of biosynthetic processGO:0009890650.100
regulation of multicellular organismal developmentGO:20000263170.098
regulation of cell communicationGO:00106461760.097
regulation of multicellular organism growthGO:00400143730.097
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.096
rna biosynthetic processGO:00327741690.096
female gamete generationGO:00072922540.093
localization of cellGO:00516743130.090
positive regulation of nucleic acid templated transcriptionGO:19035081020.089
behaviorGO:00076105270.089
organic substance biosynthetic processGO:19015763230.087
transcription dna templatedGO:00063511680.086
negative regulation of gene expression epigeneticGO:004581420.086
cellular nitrogen compound biosynthetic processGO:00442711920.084
anatomical structure formation involved in morphogenesisGO:00486462500.081
dna metabolic processGO:0006259740.080
regulation of growthGO:00400084090.079
regulation of catalytic activityGO:0050790780.079
mitotic sister chromatid segregationGO:0000070380.078
response to organic substanceGO:00100331310.078
cell divisionGO:00513012620.077
maintenance of locationGO:00512355800.075
cellular component movementGO:00069283880.074
positive regulation of signalingGO:0023056660.073
receptor mediated endocytosisGO:00068987150.073
positive regulation of macromolecule biosynthetic processGO:00105571090.073
organ morphogenesisGO:0009887670.071
body morphogenesisGO:00101716200.071
negative regulation of nucleic acid templated transcriptionGO:1903507530.071
positive regulation of transcription dna templatedGO:00458931020.071
protein localizationGO:00081042050.070
lipid localizationGO:00108765730.070
dna repairGO:0006281230.069
protein catabolic processGO:00301631620.069
regulation of nitrogen compound metabolic processGO:00511712220.069
organic cyclic compound biosynthetic processGO:19013621950.068
multi organism behaviorGO:00517053890.068
positive regulation of nucleobase containing compound metabolic processGO:00459351340.068
regulation of response to stimulusGO:00485832430.068
regulation of signalingGO:00230511720.067
positive regulation of rna biosynthetic processGO:19026801020.067
autophagyGO:0006914290.065
catabolic processGO:00090563180.064
cellular response to dna damage stimulusGO:0006974410.063
negative regulation of signal transductionGO:0009968600.063
striated muscle cell differentiationGO:00511461580.063
regulation of meiotic cell cycleGO:00514451360.063
lipid storageGO:00199155650.062
positive regulation of developmental growthGO:00486393540.062
regulation of biosynthetic processGO:00098891890.061
regulation of nuclear divisionGO:00517831150.061
positive regulation of gene expressionGO:00106281120.060
positive regulation of rna metabolic processGO:00512541030.060
cellular protein localizationGO:0034613750.060
regulation of signal transductionGO:00099661350.059
posttranscriptional gene silencingGO:00164411430.059
ribonucleoprotein complex assemblyGO:002261840.059
cellular component morphogenesisGO:00329893180.058
response to abiotic stimulusGO:00096281520.058
response to nutrient levelsGO:0031667350.058
establishment of localizationGO:005123411710.058
vesicle mediated transportGO:00161928520.057
regulation of cytoplasmic transportGO:190364930.057
regulation of cellular amino acid metabolic processGO:000652100.057
negative regulation of macromolecule biosynthetic processGO:0010558650.057
positive regulation of nitrogen compound metabolic processGO:00511731340.056
negative regulation of nucleobase containing compound metabolic processGO:0045934630.056
actomyosin structure organizationGO:00310321540.054
phosphorylationGO:00163101160.053
transcription from rna polymerase ii promoterGO:00063661490.052
regulation of multi organism processGO:0043900690.051
cellular response to organic substanceGO:00713101190.051
response to oxygen containing compoundGO:1901700440.051
regulation of phosphate metabolic processGO:0019220810.050
posttranscriptional regulation of gene expressionGO:00106081660.050
establishment of localization in cellGO:00516493180.049
phosphate containing compound metabolic processGO:00067962320.049
cellular response to chemical stimulusGO:00708871290.049
organelle assemblyGO:00709252140.048
dna packagingGO:000632370.048
striated muscle cell developmentGO:00550021570.048
defense responseGO:00069522960.047
regulation of cellular protein metabolic processGO:0032268750.047
negative regulation of transcription dna templatedGO:0045892530.046
organonitrogen compound metabolic processGO:19015641510.046
dna templated transcription elongationGO:000635410.046
neuron differentiationGO:00301822170.046
cell type specific apoptotic processGO:009728540.045
transcription elongation from rna polymerase ii promoterGO:000636810.045
actin cytoskeleton organizationGO:00300361840.044
small molecule metabolic processGO:00442811860.044
regulation of protein metabolic processGO:0051246810.044
ion transportGO:00068111130.044
positive regulation of cellular metabolic processGO:00313251780.043
cell part morphogenesisGO:00329901520.043
phosphorus metabolic processGO:00067932320.043
establishment or maintenance of cell polarityGO:0007163630.042
positive regulation of growthGO:00459273690.042
regulation of developmental growthGO:00486383890.041
positive regulation of intracellular transportGO:003238820.041
chromatin remodelingGO:000633820.041
negative regulation of post embryonic developmentGO:00485812080.041
positive regulation of molecular functionGO:0044093610.041
molting cycleGO:00423032810.040
regulation of transcription from rna polymerase ii promoterGO:00063571450.040
myofibril assemblyGO:00302391540.039
response to chemicalGO:00422213560.039
positive regulation of chromosome organizationGO:200125220.038
intracellular transportGO:0046907770.038
negative regulation of rna biosynthetic processGO:1902679530.037
homeostatic processGO:0042592510.037
positive regulation of metabolic processGO:00098931870.037
digestive tract developmentGO:00485651220.037
regulation of meiosisGO:0040020940.037
epithelial cell proliferationGO:005067310.037
macromolecule catabolic processGO:00090572020.036
regulation of localizationGO:00328791940.036
rna interferenceGO:00162461370.036
positive regulation of multicellular organism growthGO:00400183520.036
macromolecule biosynthetic processGO:00090592500.036
canonical wnt signaling pathwayGO:006007030.036
negative regulation of cellular biosynthetic processGO:0031327650.036
nucleus organizationGO:0006997380.036
gene silencing by rnaGO:00310471430.036
symbiosis encompassing mutualism through parasitismGO:004440350.035
microtubule cytoskeleton organization involved in mitosisGO:1902850120.034
inductive cell migrationGO:00400391450.034
regulation of cellular macromolecule biosynthetic processGO:20001121880.034
positive regulation of catalytic activityGO:0043085590.033
nucleoside phosphate catabolic processGO:1901292770.033
cell proliferationGO:00082831160.033
generation of neuronsGO:00486992350.033
multi multicellular organism processGO:00447063900.033
establishment of protein localization to membraneGO:009015030.033
nucleotide metabolic processGO:00091171080.032
striated muscle myosin thick filament assemblyGO:00716881380.032
regulation of nucleocytoplasmic transportGO:004682230.031
myosin filament assemblyGO:00310341380.031
negative regulation of cell communicationGO:0010648610.031
molting cycle collagen and cuticulin based cuticleGO:00189962810.030
protein phosphorylationGO:0006468850.029
muscle cell developmentGO:00550011580.029
spermatogenesisGO:0007283410.029
negative regulation of cellular metabolic processGO:0031324950.029
cellular macromolecule localizationGO:0070727750.028
regulation of transportGO:0051049910.028
cell morphogenesisGO:00009021630.028
transmembrane transportGO:00550851100.028
innate immune responseGO:00450871900.028
cellular biosynthetic processGO:00442493150.027
intracellular receptor signaling pathwayGO:003052220.027
modification dependent macromolecule catabolic processGO:0043632320.027
dna conformation changeGO:0071103110.026
phagocytosisGO:00069091150.026
intracellular signal transductionGO:0035556960.025
myosin filament organizationGO:00310331380.025
purine ribonucleoside monophosphate catabolic processGO:0009169280.025
cellular ketone metabolic processGO:0042180140.024
organophosphate metabolic processGO:00196371250.024
negative regulation of signalingGO:0023057610.024
regulation of cellular ketone metabolic processGO:001056530.024
cell fate commitmentGO:00451651390.024
regulation of cellular amine metabolic processGO:003323800.024
cellular catabolic processGO:00442481990.024
response to starvationGO:0042594260.023
negative regulation of nitrogen compound metabolic processGO:0051172630.023
system processGO:00030081360.023
positive regulation of epithelial cell proliferationGO:005067910.023
negative regulation of rna metabolic processGO:0051253530.023
amine metabolic processGO:0009308150.022
regulation of cell proliferationGO:00421271050.022
response to woundingGO:000961140.022
posttranscriptional gene silencing by rnaGO:00351941430.022
positive regulation of protein transportGO:005122240.022
negative regulation of response to stimulusGO:0048585730.022
male gamete generationGO:0048232410.022
multi organism reproductive behaviorGO:00447053870.022
regulation of sequence specific dna binding transcription factor activityGO:005109030.022
response to inorganic substanceGO:0010035500.021
spindle assemblyGO:005122580.021
regulation of phosphorylationGO:0042325450.021
organic substance transportGO:00717021130.021
cellular protein catabolic processGO:0044257370.021
embryonic morphogenesisGO:00485981520.021
oxoacid metabolic processGO:0043436470.020
digestive system developmentGO:00551231220.020
cellular nitrogen compound catabolic processGO:00442701190.020
cellular amine metabolic processGO:0044106150.020
cellular amino acid metabolic processGO:0006520150.020
epithelial tube morphogenesisGO:006056210.020
cell substrate adhesionGO:003158910.020
cation transportGO:0006812780.020
sister chromatid segregationGO:0000819460.020
purine ribonucleoside metabolic processGO:0046128920.020
regulation of apoptotic processGO:0042981360.019
positive regulation of cell communicationGO:0010647690.019
protein modification by small protein conjugation or removalGO:0070647400.019
positive regulation of apoptotic processGO:0043065170.019
cell morphogenesis involved in neuron differentiationGO:00486671110.019
modification dependent protein catabolic processGO:0019941320.019
regulation of protein targetingGO:190353330.019
positive regulation of cell deathGO:0010942380.018
regulation of locomotionGO:00400121610.018
single organism biosynthetic processGO:0044711910.018
regulation of protein import into nucleusGO:004230630.018
tissue developmentGO:00098881120.018
organic acid metabolic processGO:0006082470.018
chromatin assemblyGO:003149710.018
positive regulation of proteasomal protein catabolic processGO:190180010.018
single organism behaviorGO:0044708830.018
positive regulation of biosynthetic processGO:00098911090.018
positive regulation of signal transductionGO:0009967400.018
regulation of apoptotic signaling pathwayGO:200123310.017
divalent metal ion transportGO:0070838170.017
peptidyl tyrosine phosphorylationGO:001810820.017
cellular component assembly involved in morphogenesisGO:00109271830.017
regulation of macromolecule biosynthetic processGO:00105561890.017
sensory organ morphogenesisGO:009059620.017
spindle organizationGO:0007051920.017
ribonucleoside triphosphate metabolic processGO:0009199870.017
cytokinesisGO:0000910800.016
regulation of ion transportGO:0043269390.016
negative regulation of cell cycleGO:0045786530.016
rna localizationGO:000640330.016
neuron projection morphogenesisGO:00488121140.016
nitrogen compound transportGO:0071705490.016
regulation of cell deathGO:0010941650.016
purine ribonucleoside monophosphate metabolic processGO:0009167430.016
carboxylic acid metabolic processGO:0019752340.015
positive regulation of neurogenesisGO:005076940.015
establishment of organelle localizationGO:00516561230.015
regulation of cellular component movementGO:0051270620.015
peptidyl amino acid modificationGO:0018193580.015
organelle localizationGO:00516401270.015
regulation of chromosome organizationGO:0033044200.015
regulation of organ morphogenesisGO:200002740.015
nucleoside monophosphate metabolic processGO:0009123460.015
purine containing compound metabolic processGO:0072521950.015
rna transportGO:005065830.015
cytoskeleton dependent cytokinesisGO:0061640350.014
organonitrogen compound catabolic processGO:1901565900.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.014
regulation of programmed cell deathGO:0043067500.014
membrane organizationGO:00610241350.014
cell morphogenesis involved in differentiationGO:00009041120.014
positive regulation of cellular protein catabolic processGO:190336430.014
regulation of cell migrationGO:0030334550.014
nucleic acid transportGO:005065730.014
cellular response to abiotic stimulusGO:007121440.014
cell projection morphogenesisGO:00488581480.014
secretion by cellGO:00329401380.014
protein oligomerizationGO:005125940.014
neuron recognitionGO:0008038830.013
oocyte developmentGO:0048599440.013
proteolysis involved in cellular protein catabolic processGO:0051603320.013
negative regulation of neurogenesisGO:005076840.013
secretionGO:00469031470.013
regulation of canonical wnt signaling pathwayGO:006082810.013
regulation of cellular component biogenesisGO:0044087260.013
oocyte differentiationGO:0009994450.013
positive regulation of programmed cell deathGO:0043068270.013
organophosphate catabolic processGO:0046434810.013
positive regulation of intracellular protein transportGO:009031620.013
regulation of mapk cascadeGO:0043408230.013
regulation of protein complex assemblyGO:0043254120.012
oocyte axis specificationGO:000730920.012
dna replicationGO:0006260150.012
positive regulation of transportGO:0051050320.012
mapk cascadeGO:0000165310.012
axon developmentGO:00615641630.012
internal peptidyl lysine acetylationGO:001839330.012
peptidyl lysine acetylationGO:001839430.012
purine nucleoside metabolic processGO:0042278920.012
aromatic compound catabolic processGO:00194391160.012
feeding behaviorGO:0007631700.012
pharynx developmentGO:0060465510.012
neuron apoptotic processGO:005140240.012
positive regulation of protein metabolic processGO:0051247450.012
regulation of response to stressGO:0080134280.012
regulation of cytoskeleton organizationGO:0051493410.012
regulation of atp catabolic processGO:190328930.012
cellular response to nutrient levelsGO:0031669130.012
taxisGO:00423301280.012
apoptotic cell clearanceGO:00432771110.012
regulation of microtubule cytoskeleton organizationGO:0070507210.012
ion homeostasisGO:0050801210.011
ribonucleoside catabolic processGO:0042454770.011
regulation of behaviorGO:0050795970.011
carbohydrate derivative catabolic processGO:1901136820.011
positive regulation of vulval developmentGO:0040026520.011
chemical homeostasisGO:0048878290.011
nucleoside phosphate metabolic processGO:00067531080.011
regulation of chromatin organizationGO:190227520.011
single organism membrane fusionGO:0044801130.011
regulation of transferase activityGO:0051338310.011
g1 s transition of mitotic cell cycleGO:000008220.011
ribose phosphate metabolic processGO:0019693990.011
divalent inorganic cation transportGO:0072511170.011
mrna metabolic processGO:0016071310.011
regulation of epithelial cell proliferationGO:005067810.011
modification of morphology or physiology of other organismGO:003582120.011
purine nucleoside catabolic processGO:0006152750.011
purine ribonucleotide metabolic processGO:0009150950.011
negative regulation of organelle organizationGO:0010639200.011
regulation of protein stabilityGO:003164730.010
muscle fiber developmentGO:004874720.010
response to external biotic stimulusGO:00432071010.010
chemotaxisGO:00069351200.010
regulation of protein localizationGO:0032880500.010
purine nucleoside monophosphate metabolic processGO:0009126430.010
positive regulation of proteolysis involved in cellular protein catabolic processGO:190305210.010
anterior posterior pattern specificationGO:0009952270.010

kle-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.039
disease of anatomical entityDOID:700.035
cancerDOID:16200.026
organ system cancerDOID:005068600.026
gastrointestinal system cancerDOID:311900.018
intestinal cancerDOID:1015500.017
large intestine cancerDOID:567200.017
nervous system diseaseDOID:86300.013