Caenorhabditis elegans

9 known processes

mec-2 (CELE_F14D12.4)

Protein MEC-2

mec-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo developmentGO:000979030520.729
Worm
reproductive structure developmentGO:00486088500.726
response to anestheticGO:007234710.634
embryo development ending in birth or egg hatchingGO:000979229920.625
Worm
nervous system developmentGO:00073992530.621
gonad developmentGO:00084068400.609
genitalia developmentGO:00488067410.589
gamete generationGO:00072764610.584
intercellular transportGO:001049610.561
organ developmentGO:004851311020.545
single organism reproductive processGO:004470211960.542
reproductive system developmentGO:00614588500.528
phosphorylationGO:00163101160.523
protein phosphorylationGO:0006468850.511
developmental process involved in reproductionGO:000300611650.502
signal transduction by phosphorylationGO:0023014310.502
apoptotic processGO:00069154780.496
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.491
regulation of ion transmembrane transportGO:0034765190.489
axonogenesisGO:00074091020.481
sex differentiationGO:00075489090.479
establishment of localizationGO:005123411710.475
Worm
cell deathGO:00082195470.461
regulation of signal transductionGO:00099661350.439
hermaphrodite genitalia developmentGO:00400357340.438
mapk cascadeGO:0000165310.437
cellular process involved in reproduction in multicellular organismGO:00224123510.436
single organism organelle organizationGO:19025895010.434
development of primary sexual characteristicsGO:00451378400.434
sexual reproductionGO:00199535460.433
cell developmentGO:00484686960.407
phosphorus metabolic processGO:00067932320.389
locomotionGO:004001116340.387
negative regulation of cation channel activityGO:200125820.385
cellular component morphogenesisGO:00329893180.374
signalingGO:00230524010.373
post embryonic developmentGO:000979121520.370
Worm
cellular component biogenesisGO:00440852970.359
cell motilityGO:00488703130.354
regulation of primary metabolic processGO:00800902920.347
organelle organizationGO:00069967830.341
regulation of pharyngeal pumpingGO:0043051360.339
regulation of metabolic processGO:00192224780.332
germ cell developmentGO:00072813510.330
phosphate containing compound metabolic processGO:00067962320.324
regulation of mapk cascadeGO:0043408230.319
signal transductionGO:00071653170.317
regulation of cation channel activityGO:200125730.315
deathGO:00162655470.311
female gamete generationGO:00072922540.310
regulation of response to stimulusGO:00485832430.310
regulation of macromolecule metabolic processGO:00602554210.308
regulation of developmental processGO:00507936840.305
cell migrationGO:00164773060.292
regulation of cell developmentGO:0060284490.292
multi organism reproductive processGO:00447038670.290
programmed cell deathGO:00125015000.287
oogenesisGO:00484772290.287
generation of neuronsGO:00486992350.281
regulation of cell differentiationGO:0045595810.278
organic substance catabolic processGO:19015752940.274
Worm
protein catabolic processGO:00301631620.274
Worm
response to chemicalGO:00422213560.274
Worm
inactivation of mapkkk activityGO:005139020.271
negative regulation of response to stimulusGO:0048585730.270
pattern specification processGO:0007389590.249
taxisGO:00423301280.245
multicellular organism reproductionGO:00325048190.245
cellular component movementGO:00069283880.239
cell morphogenesis involved in neuron differentiationGO:00486671110.237
multicellular organismal agingGO:00102598120.232
negative regulation of ion transmembrane transportGO:003476630.231
macromolecule catabolic processGO:00090572020.230
Worm
regulation of phosphorus metabolic processGO:0051174810.229
ovipositionGO:00189913640.227
cytoskeleton organizationGO:00070103390.224
embryonic morphogenesisGO:00485981520.222
negative regulation of signal transductionGO:0009968600.219
positive regulation of multicellular organismal processGO:00512404170.210
endocytosisGO:00068978190.208
regulation of multicellular organismal developmentGO:20000263170.202
positive regulation of developmental processGO:00510944080.201
neuron projection developmentGO:00311751870.199
negative regulation of biological processGO:00485195670.197
regulation of transportGO:0051049910.193
regulation of multicellular organismal processGO:00512397260.192
negative regulation of multicellular organismal processGO:00512412360.190
oocyte developmentGO:0048599440.190
receptor mediated endocytosisGO:00068987150.189
determination of adult lifespanGO:00083408120.184
protein modification processGO:00362112070.184
regulation of defecation rhythmGO:200074630.183
transportGO:000681010930.180
embryonic body morphogenesisGO:0010172490.180
body morphogenesisGO:00101716200.178
multicellular organismal reproductive processGO:00486098150.177
regulation of neuron differentiationGO:0045664400.176
cellular protein metabolic processGO:00442672790.175
muscle structure developmentGO:00610611910.170
neuron projection guidanceGO:0097485820.170
single organism localizationGO:19025785180.167
regulation of intracellular signal transductionGO:1902531770.165
chemotaxisGO:00069351200.162
protein localizationGO:00081042050.161
Worm
neurogenesisGO:00220082360.160
anatomical structure formation involved in morphogenesisGO:00486462500.160
regulation of oocyte maturationGO:190019370.158
behaviorGO:00076105270.152
single organism signalingGO:00447004010.151
regulation of cell communicationGO:00106461760.147
motor neuron axon guidanceGO:0008045130.146
negative regulation of cell communicationGO:0010648610.145
ion transportGO:00068111130.145
defecation rhythmGO:003588230.143
negative regulation of cellular protein metabolic processGO:0032269270.141
macromolecular complex subunit organizationGO:00439333200.140
oocyte differentiationGO:0009994450.139
negative regulation of protein serine threonine kinase activityGO:007190160.138
macromolecule modificationGO:00434122180.137
cell cell signalingGO:00072671180.136
regulation of developmental growthGO:00486383890.132
negative regulation of macromolecule metabolic processGO:00106052290.132
macromolecule localizationGO:00330367710.132
Worm
regulation of cellular metabolic processGO:00313233050.132
negative regulation of transporter activityGO:003241030.129
actin filament based processGO:00300291910.127
single organism transportGO:00447654470.124
negative regulation of cellular processGO:00485232390.123
regulation of signalingGO:00230511720.121
single organism cellular localizationGO:1902580720.120
regulation of protein serine threonine kinase activityGO:0071900180.120
regulation of rna metabolic processGO:00512521730.120
developmental growthGO:00485894120.118
regulation of phosphate metabolic processGO:0019220810.117
nucleic acid metabolic processGO:00903042990.115
feeding behaviorGO:0007631700.115
microtubule based movementGO:0007018330.115
positive regulation of rna biosynthetic processGO:19026801020.114
localization of cellGO:00516743130.114
digestive tract developmentGO:00485651220.113
positive regulation of developmental growthGO:00486393540.113
cellular protein complex assemblyGO:00436231780.112
cellular component assemblyGO:00226072930.112
cell projection morphogenesisGO:00488581480.111
organelle assemblyGO:00709252140.110
developmental maturationGO:0021700260.110
membrane organizationGO:00610241350.110
multi multicellular organism processGO:00447063900.109
negative regulation of protein metabolic processGO:0051248270.109
actin cytoskeleton organizationGO:00300361840.108
regulation of nucleic acid templated transcriptionGO:19035061650.108
cell projection organizationGO:00300302310.108
regulation of growthGO:00400084090.108
sensory organ morphogenesisGO:009059620.107
regulation of phosphorylationGO:0042325450.107
vesicle mediated transportGO:00161928520.107
multi organism reproductive behaviorGO:00447053870.106
regulation of reproductive processGO:2000241660.105
regulation of gene expressionGO:00104683660.105
cell maturationGO:0048469260.105
cellular protein modification processGO:00064642070.105
system processGO:00030081360.104
intracellular signal transductionGO:0035556960.104
cell surface receptor signaling pathwayGO:00071661490.103
striated muscle cell differentiationGO:00511461580.103
negative regulation of developmental processGO:00510932270.102
positive regulation of cellular processGO:00485223320.101
regulation of biological qualityGO:00650087410.101
response to external stimulusGO:00096052890.101
eating behaviorGO:0042755590.100
ion transmembrane transportGO:0034220910.100
regulation of protein metabolic processGO:0051246810.099
multi organism behaviorGO:00517053890.096
muscle cell differentiationGO:00426921710.096
protein complex biogenesisGO:00702711860.095
agingGO:00075688120.095
microtubule based processGO:00070171820.094
neuron projection morphogenesisGO:00488121140.094
protein complex subunit organizationGO:00718222800.094
reproductive behaviorGO:00190983870.092
positive regulation of growthGO:00459273690.090
regulation of transferase activityGO:0051338310.090
transcription dna templatedGO:00063511680.089
response to abiotic stimulusGO:00096281520.089
positive regulation of multicellular organism growthGO:00400183520.089
regulation of synaptic transmissionGO:0050804340.089
epithelial cell proliferationGO:005067310.088
actomyosin structure organizationGO:00310321540.088
determination of left right symmetryGO:000736890.087
negative regulation of cell maturationGO:190343050.087
multicellular organism growthGO:00352643850.087
regulation of catalytic activityGO:0050790780.087
regulation of feeding behaviorGO:0060259380.085
positive regulation of neurogenesisGO:005076940.085
multicellular organismal reproductive behaviorGO:00330573840.084
regulation of transcription dna templatedGO:00063551640.084
lipid localizationGO:00108765730.084
regulation of behaviorGO:0050795970.084
striated muscle cell developmentGO:00550021570.082
negative regulation of transmembrane transportGO:003476330.081
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010160.081
regulation of multicellular organism growthGO:00400143730.080
cellular response to chemical stimulusGO:00708871290.079
head developmentGO:006032210.078
maintenance of locationGO:00512355800.078
regulation of cell morphogenesis involved in differentiationGO:0010769290.076
negative regulation of ion transmembrane transporter activityGO:003241330.075
axon developmentGO:00615641630.074
protein metabolic processGO:00195384220.074
Worm
positive regulation of cellular biosynthetic processGO:00313281090.074
lipid storageGO:00199155650.072
macromolecular complex assemblyGO:00650031930.070
regulation of cellular component organizationGO:00511282480.070
catabolic processGO:00090563180.069
Worm
regulation of protein kinase activityGO:0045859280.069
cell cycle processGO:00224024820.068
striated muscle myosin thick filament assemblyGO:00716881380.067
male mating behaviorGO:0060179260.067
positive regulation of neuron differentiationGO:004566640.067
axon guidanceGO:0007411820.067
regulation of kinase activityGO:0043549290.067
muscle cell developmentGO:00550011580.065
organelle fissionGO:00482853630.065
negative regulation of cellular metabolic processGO:0031324950.065
negative regulation of signalingGO:0023057610.064
regulation of nematode larval developmentGO:00610622600.064
transmembrane transportGO:00550851100.063
excretionGO:0007588490.063
establishment or maintenance of cell polarityGO:0007163630.062
regulation of multi organism processGO:0043900690.060
regulation of molecular functionGO:0065009890.058
synaptic transmissionGO:00072681060.057
positive regulation of metabolic processGO:00098931870.056
mechanosensory behaviorGO:0007638250.056
regulation of cell proliferationGO:00421271050.056
negative regulation of metabolic processGO:00098922400.055
cellular macromolecular complex assemblyGO:00346221840.055
single organism membrane organizationGO:0044802350.055
mitotic cell cycle processGO:19030471940.054
cell divisionGO:00513012620.054
chemosensory behaviorGO:0007635330.053
neuron differentiationGO:00301822170.053
vulval developmentGO:00400253330.053
positive regulation of cellular metabolic processGO:00313251780.052
cellular response to organic substanceGO:00713101190.052
positive regulation of neuron projection developmentGO:001097640.052
organic cyclic compound biosynthetic processGO:19013621950.052
positive regulation of cell projection organizationGO:003134640.051
cell morphogenesisGO:00009021630.051
cellular macromolecule biosynthetic processGO:00346452470.051
gene expressionGO:00104674120.051
meiotic cell cycleGO:00513213350.050
regulation of cellular protein metabolic processGO:0032268750.049
regulation of nitrogen compound metabolic processGO:00511712220.049
epithelium developmentGO:0060429680.048
myosin filament organizationGO:00310331380.048
nucleobase containing compound metabolic processGO:00061394060.048
regulation of cell migrationGO:0030334550.047
myofibril assemblyGO:00302391540.047
macromolecule biosynthetic processGO:00090592500.047
canonical wnt signaling pathwayGO:006007030.047
myosin filament assemblyGO:00310341380.047
regulation of cellular component sizeGO:0032535400.047
cellular component assembly involved in morphogenesisGO:00109271830.045
asymmetric protein localizationGO:0008105350.045
cell cycleGO:00070495260.044
positive regulation of signal transductionGO:0009967400.044
ovulationGO:0030728330.043
regulation of cell morphogenesisGO:0022604400.043
negative regulation of reproductive processGO:2000242190.043
positive regulation of cell communicationGO:0010647690.043
secretionGO:00469031470.043
response to organic substanceGO:00100331310.041
defense responseGO:00069522960.041
regulation of secretionGO:0051046290.040
rna metabolic processGO:00160702280.039
regulation of cytoplasmic transportGO:190364930.039
molting cycleGO:00423032810.039
collagen and cuticulin based cuticle developmentGO:0040002990.039
regulation of cellular biosynthetic processGO:00313261890.039
cellular localizationGO:00516413600.038
cell type specific apoptotic processGO:009728540.038
enzyme linked receptor protein signaling pathwayGO:0007167500.038
response to woundingGO:000961140.037
tube developmentGO:00352951260.037
regulation of epithelial cell proliferationGO:005067810.037
nucleic acid templated transcriptionGO:00976591690.036
rna biosynthetic processGO:00327741690.036
regulation of apoptotic processGO:0042981360.035
cell fate commitmentGO:00451651390.035
metal ion transportGO:0030001490.034
mating behaviorGO:0007617320.034
growthGO:00400075620.034
Worm
negative regulation of ion transportGO:004327170.034
nucleobase containing compound biosynthetic processGO:00346541840.034
molting cycle collagen and cuticulin based cuticleGO:00189962810.034
transcription from rna polymerase ii promoterGO:00063661490.034
pharyngeal pumpingGO:0043050580.033
negative regulation of catalytic activityGO:0043086150.033
establishment of localization in cellGO:00516493180.033
cell proliferationGO:00082831160.032
ribonucleoside metabolic processGO:0009119980.032
positive regulation of rna metabolic processGO:00512541030.032
response to drugGO:0042493140.032
Worm
cellular response to endogenous stimulusGO:0071495320.032
regulation of neuromuscular synaptic transmissionGO:190007310.032
organ morphogenesisGO:0009887670.032
regulation of post embryonic developmentGO:00485802600.030
purine containing compound metabolic processGO:0072521950.030
cell part morphogenesisGO:00329901520.030
regulation of nucleobase containing compound metabolic processGO:00192192220.030
regulation of axon extensionGO:0030516200.029
aromatic compound biosynthetic processGO:00194381920.029
protein localization to membraneGO:0072657110.029
neuron projection extensionGO:1990138370.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.028
nematode male tail tip morphogenesisGO:0045138770.028
cellular response to abiotic stimulusGO:007121440.028
defecationGO:0030421470.028
regulation of cell projection organizationGO:0031344380.028
response to other organismGO:00517071010.028
digestive system developmentGO:00551231220.028
neuron developmentGO:00486661990.028
negative regulation of gene expressionGO:00106292170.028
cellular biosynthetic processGO:00442493150.028
regulation of localizationGO:00328791940.027
defense response to other organismGO:00985421000.027
determination of bilateral symmetryGO:000985590.027
regulation of ion transportGO:0043269390.027
neuromuscular synaptic transmissionGO:000727460.027
cell growthGO:0016049440.027
regulation of nucleocytoplasmic transportGO:004682230.026
protein complex assemblyGO:00064611860.026
small molecule metabolic processGO:00442811860.026
single organism intracellular transportGO:1902582700.026
ras protein signal transductionGO:0007265310.025
matingGO:0007618340.025
negative regulation of wnt signaling pathwayGO:003017860.025
regulation of macromolecule biosynthetic processGO:00105561890.025
regulation of meiotic cell cycleGO:00514451360.025
male anatomical structure morphogenesisGO:0090598780.025
meiotic cell cycle processGO:19030461700.024
regulation of cell sizeGO:0008361300.024
positive regulation of macromolecule metabolic processGO:00106041490.024
regulation of wnt signaling pathwayGO:003011190.024
regulation of transmembrane transportGO:0034762190.024
regulation of cell cycleGO:00517261940.024
regulation of axonogenesisGO:0050770240.024
regulation of biosynthetic processGO:00098891890.024
cuticle developmentGO:00423351000.023
cellular response to transforming growth factor beta stimulusGO:0071560130.023
regulation of oocyte developmentGO:006028180.022
axon extensionGO:0048675370.022
adult locomotory behaviorGO:000834410.022
regulation of vulval developmentGO:00400282480.022
insulin receptor signaling pathwayGO:0008286140.022
regulation of cellular macromolecule biosynthetic processGO:20001121880.021
nucleobase containing compound catabolic processGO:00346551140.021
positive regulation of macromolecule biosynthetic processGO:00105571090.021
regulation of protein localizationGO:0032880500.021
regulation of neuron projection developmentGO:0010975310.021
regulation of transcription from rna polymerase ii promoterGO:00063571450.021
regulation of canonical wnt signaling pathwayGO:006082810.020
negative regulation of mapk cascadeGO:0043409100.020
post embryonic organ developmentGO:00485693360.020
biosynthetic processGO:00090583230.020
organonitrogen compound metabolic processGO:19015641510.020
regulation of g protein coupled receptor protein signaling pathwayGO:000827740.020
response to peptide hormoneGO:0043434140.020
positive regulation of response to stimulusGO:0048584550.020
positive regulation of transcription dna templatedGO:00458931020.020
establishment of spindle localizationGO:0051293510.020
spindle organizationGO:0007051920.020
response to insulinGO:0032868140.020
establishment of cell polarityGO:0030010460.020
organic substance biosynthetic processGO:19015763230.020
positive regulation of intracellular transportGO:003238820.020
negative regulation of cellular component organizationGO:0051129330.019
epithelial tube morphogenesisGO:006056210.019
single organism behaviorGO:0044708830.019
wnt signaling pathwayGO:0016055270.019
positive regulation of nucleobase containing compound metabolic processGO:00459351340.019
membrane invaginationGO:0010324980.019
regulation of response to woundingGO:190303410.019
response to fungusGO:0009620200.019
digestive tract morphogenesisGO:0048546760.018
negative regulation of nitrogen compound metabolic processGO:0051172630.018
small gtpase mediated signal transductionGO:0007264320.018
regulation of anatomical structure sizeGO:0090066460.018
regulation of anatomical structure morphogenesisGO:0022603510.018
apoptotic cell clearanceGO:00432771110.018
regulation of cellular component movementGO:0051270620.018
cellular protein localizationGO:0034613750.018
dendrite developmentGO:0016358420.018
organic acid metabolic processGO:0006082470.018
response to biotic stimulusGO:00096071010.017
regulation of system processGO:0044057270.017
response to heatGO:0009408500.017
positive regulation of cell migrationGO:003033530.017
regulation of protein modification processGO:0031399460.017
negative regulation of macromolecule biosynthetic processGO:0010558650.017
epithelial cell morphogenesisGO:000338220.016
establishment of protein localizationGO:0045184500.016
Worm
response to external biotic stimulusGO:00432071010.016
regulation of locomotionGO:00400121610.016
specification of symmetryGO:000979990.016
positive regulation of biosynthetic processGO:00098911090.016
regulation of protein import into nucleusGO:004230630.015
actin filament organizationGO:0007015210.015
cell substrate adhesionGO:003158910.015
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.015
epithelial cell differentiationGO:0030855170.015
regulation of cytoskeleton organizationGO:0051493410.015
purine nucleoside triphosphate metabolic processGO:0009144870.015
positive regulation of gene expressionGO:00106281120.015
positive regulation of protein transportGO:005122240.015
phagocytosis engulfmentGO:0006911980.015
negative regulation of rna metabolic processGO:0051253530.015
nucleoside phosphate metabolic processGO:00067531080.015
regulation of cell motilityGO:2000145570.015
regulation of response to external stimulusGO:0032101290.015
phagocytosisGO:00069091150.014
cellular macromolecule localizationGO:0070727750.014
regulation of organ morphogenesisGO:200002740.014
engulfment of apoptotic cellGO:0043652940.014
skeletal muscle organ developmentGO:006053830.014
negative regulation of intracellular signal transductionGO:1902532330.014
regulation of organelle organizationGO:00330431640.014
regulation of cell deathGO:0010941650.014
response to endoplasmic reticulum stressGO:0034976710.014
negative regulation of biosynthetic processGO:0009890650.014
response to endogenous stimulusGO:0009719330.014
ribonucleotide metabolic processGO:0009259990.014
organic substance transportGO:00717021130.014
posttranscriptional gene silencing by rnaGO:00351941430.014
regenerationGO:003109940.013
organophosphate metabolic processGO:00196371250.013
regulation of apoptotic signaling pathwayGO:200123310.013
hatchingGO:0035188480.013
regulation of protein targetingGO:190353330.013
negative regulation of response to external stimulusGO:003210230.013
inductive cell migrationGO:00400391450.013
carboxylic acid metabolic processGO:0019752340.013
male sex differentiationGO:0046661860.013
establishment of organelle localizationGO:00516561230.013
cytoskeleton dependent intracellular transportGO:0030705190.013
muscle organ developmentGO:0007517260.013
response to organonitrogen compoundGO:0010243150.013
response to bacteriumGO:0009617860.013
regulation of nuclear divisionGO:00517831150.013
negative regulation of nucleic acid templated transcriptionGO:1903507530.013
cellular nitrogen compound biosynthetic processGO:00442711920.013
microtubule based transportGO:0010970190.012
regulation of purine nucleotide metabolic processGO:1900542370.012
adult behaviorGO:003053430.012
cell adhesionGO:0007155210.012
response to nitrogen compoundGO:1901698250.012
response to growth factorGO:0070848180.012
regulation of epithelial cell differentiationGO:003085640.012
response to temperature stimulusGO:0009266660.012
response to mechanical stimulusGO:0009612280.012
defense response to bacteriumGO:0042742860.012
regulation of programmed cell deathGO:0043067500.012
regulation of mitotic cell cycleGO:0007346760.012
peptidyl tyrosine phosphorylationGO:001810820.012
negative regulation of post embryonic developmentGO:00485812080.012
regulation of cellular ketone metabolic processGO:001056530.012
cell projection assemblyGO:0030031350.012
regulation of nervous system developmentGO:0051960410.012
cell morphogenesis involved in differentiationGO:00009041120.012
mitotic spindle organizationGO:0007052810.012
negative regulation of cell developmentGO:001072190.012
neuromuscular junction developmentGO:000752820.012
hormone transportGO:000991420.011
chromosome segregationGO:00070591800.011
regulation of lipid metabolic processGO:001921640.011
positive regulation of nematode larval developmentGO:0061063540.011
regulation of cellular amino acid metabolic processGO:000652100.011
rna interferenceGO:00162461370.011
cell junction organizationGO:0034330180.011
oxoacid metabolic processGO:0043436470.011
purine ribonucleoside metabolic processGO:0046128920.011
tissue morphogenesisGO:0048729650.011
organic cyclic compound catabolic processGO:19013611190.011
neuron recognitionGO:0008038830.011
positive regulation of signalingGO:0023056660.011
carbohydrate derivative catabolic processGO:1901136820.011
regulation of cell divisionGO:00513021420.011
dauer larval developmentGO:0040024920.011
negative regulation of oocyte developmentGO:006028350.011
aromatic compound catabolic processGO:00194391160.011
detection of abiotic stimulusGO:000958240.011
nucleoside metabolic processGO:0009116990.011
carbohydrate derivative metabolic processGO:19011351410.010

mec-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.022
disease of cellular proliferationDOID:1456600.022
organ system cancerDOID:005068600.022
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.013