Caenorhabditis elegans

71 known processes

unc-45 (CELE_F30H5.1)

Protein UNC-45

unc-45 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.603
post embryonic developmentGO:000979121520.577
ribonucleoside triphosphate metabolic processGO:0009199870.491
embryo developmentGO:000979030520.474
regulation of nucleoside metabolic processGO:0009118370.455
muscle tissue developmentGO:006053710.437
Zebrafish
purine nucleotide catabolic processGO:0006195750.420
purine containing compound catabolic processGO:0072523750.409
regulation of nucleotide catabolic processGO:0030811350.399
glycosyl compound catabolic processGO:1901658790.398
nucleotide metabolic processGO:00091171080.397
regulation of purine nucleotide catabolic processGO:0033121350.370
regulation of nitrogen compound metabolic processGO:00511712220.370
reproductive system developmentGO:00614588500.368
vesicle mediated transportGO:00161928520.366
carbohydrate derivative catabolic processGO:1901136820.360
purine ribonucleoside triphosphate catabolic processGO:0009207720.359
regulation of developmental processGO:00507936840.357
single organism reproductive processGO:004470211960.346
establishment of localizationGO:005123411710.343
organophosphate catabolic processGO:0046434810.341
purine ribonucleoside metabolic processGO:0046128920.331
ribonucleotide catabolic processGO:0009261750.328
heterocycle catabolic processGO:00467001190.323
hermaphrodite genitalia developmentGO:00400357340.296
nucleoside phosphate catabolic processGO:1901292770.293
reproductive structure developmentGO:00486088500.293
nucleoside triphosphate catabolic processGO:0009143720.293
purine nucleoside triphosphate catabolic processGO:0009146720.290
cytoskeleton organizationGO:00070103390.285
purine ribonucleoside triphosphate metabolic processGO:0009205870.277
muscle system processGO:0003012430.273
organ developmentGO:004851311020.267
Zebrafish
single organism localizationGO:19025785180.266
carbohydrate derivative metabolic processGO:19011351410.261
gonad developmentGO:00084068400.261
locomotionGO:004001116340.254
multicellular organism reproductionGO:00325048190.251
ribonucleoside catabolic processGO:0042454770.246
cell cycle processGO:00224024820.246
receptor mediated endocytosisGO:00068987150.244
purine ribonucleoside catabolic processGO:0046130750.238
skeletal muscle organ developmentGO:006053830.236
Zebrafish
cell developmentGO:00484686960.236
regulation of organelle organizationGO:00330431640.234
muscle structure developmentGO:00610611910.229
nucleoside catabolic processGO:0009164780.226
purine nucleoside catabolic processGO:0006152750.226
regulation of developmental growthGO:00486383890.226
developmental growthGO:00485894120.221
regulation of nucleic acid templated transcriptionGO:19035061650.219
organonitrogen compound catabolic processGO:1901565900.216
regulation of purine nucleotide metabolic processGO:1900542370.214
regulation of catabolic processGO:0009894570.212
axon developmentGO:00615641630.208
nucleoside metabolic processGO:0009116990.206
nucleoside phosphate metabolic processGO:00067531080.206
aromatic compound catabolic processGO:00194391160.205
determination of adult lifespanGO:00083408120.205
negative regulation of biological processGO:00485195670.202
regulation of molecular functionGO:0065009890.202
purine ribonucleotide metabolic processGO:0009150950.199
transportGO:000681010930.197
purine nucleoside metabolic processGO:0042278920.196
nucleotide catabolic processGO:0009166770.196
establishment of localization in cellGO:00516493180.194
organic substance catabolic processGO:19015752940.191
multicellular organismal agingGO:00102598120.190
actomyosin structure organizationGO:00310321540.188
nucleic acid metabolic processGO:00903042990.185
purine ribonucleotide catabolic processGO:0009154750.183
cellular component morphogenesisGO:00329893180.183
single organism signalingGO:00447004010.182
ovipositionGO:00189913640.182
cellular nitrogen compound catabolic processGO:00442701190.181
organonitrogen compound metabolic processGO:19015641510.181
regulation of locomotionGO:00400121610.181
ribose phosphate metabolic processGO:0019693990.180
small molecule metabolic processGO:00442811860.177
actin cytoskeleton organizationGO:00300361840.177
regulation of cellular metabolic processGO:00313233050.176
ribonucleoside triphosphate catabolic processGO:0009203720.172
regulation of primary metabolic processGO:00800902920.168
regulation of cellular component organizationGO:00511282480.166
glycosyl compound metabolic processGO:19016571000.166
catabolic processGO:00090563180.165
organic cyclic compound catabolic processGO:19013611190.165
regulation of cellular biosynthetic processGO:00313261890.165
nucleoside triphosphate metabolic processGO:0009141870.164
body morphogenesisGO:00101716200.164
cellular component movementGO:00069283880.164
developmental process involved in reproductionGO:000300611650.158
striated muscle cell developmentGO:00550021570.156
regulation of biological qualityGO:00650087410.152
muscle cell developmentGO:00550011580.152
cellular macromolecule biosynthetic processGO:00346452470.151
development of primary sexual characteristicsGO:00451378400.151
purine nucleoside triphosphate metabolic processGO:0009144870.150
organelle organizationGO:00069967830.149
ribonucleoside metabolic processGO:0009119980.149
regulation of macromolecule metabolic processGO:00602554210.148
cellular biosynthetic processGO:00442493150.145
striated muscle cell differentiationGO:00511461580.143
atp metabolic processGO:0046034420.142
heterocycle biosynthetic processGO:00181301870.142
sex differentiationGO:00075489090.141
regulation of multicellular organismal developmentGO:20000263170.141
cellular catabolic processGO:00442481990.140
multi organism behaviorGO:00517053890.139
regulation of multicellular organismal processGO:00512397260.139
signalingGO:00230524010.138
regulation of rna biosynthetic processGO:20011411650.137
muscle contractionGO:0006936430.135
multi organism reproductive processGO:00447038670.134
anatomical structure formation involved in morphogenesisGO:00486462500.134
regulation of atp catabolic processGO:190328930.134
endocytosisGO:00068978190.133
generation of neuronsGO:00486992350.131
cellular localizationGO:00516413600.131
single organism catabolic processGO:00447121290.130
regulation of nucleobase containing compound metabolic processGO:00192192220.129
regulation of growthGO:00400084090.129
macromolecule biosynthetic processGO:00090592500.129
biosynthetic processGO:00090583230.126
regulation of actin filament based processGO:0032970220.126
protein metabolic processGO:00195384220.125
organic substance biosynthetic processGO:19015763230.122
multicellular organismal reproductive processGO:00486098150.121
single organism organelle organizationGO:19025895010.119
growthGO:00400075620.117
skeletal muscle thin filament assemblyGO:003024030.114
myofibril assemblyGO:00302391540.114
cellular process involved in reproduction in multicellular organismGO:00224123510.114
multi multicellular organism processGO:00447063900.113
behaviorGO:00076105270.113
multicellular organismal reproductive behaviorGO:00330573840.112
nucleobase containing compound biosynthetic processGO:00346541840.111
cell part morphogenesisGO:00329901520.111
regulation of cellular macromolecule biosynthetic processGO:20001121880.111
neuron differentiationGO:00301822170.110
nucleobase containing small molecule metabolic processGO:00550861150.110
agingGO:00075688120.110
regulation of cytoskeleton organizationGO:0051493410.110
muscle cell differentiationGO:00426921710.109
cellular macromolecular complex assemblyGO:00346221840.107
genitalia developmentGO:00488067410.106
cell deathGO:00082195470.105
female gamete generationGO:00072922540.103
organophosphate metabolic processGO:00196371250.102
regulation of metabolic processGO:00192224780.101
ribonucleotide metabolic processGO:0009259990.100
nucleic acid templated transcriptionGO:00976591690.100
ribonucleoside monophosphate metabolic processGO:0009161450.099
cellular component assemblyGO:00226072930.098
protein complex assemblyGO:00064611860.094
cell cycleGO:00070495260.094
cell projection organizationGO:00300302310.093
deathGO:00162655470.090
regulation of transcription from rna polymerase ii promoterGO:00063571450.087
macromolecular complex subunit organizationGO:00439333200.087
macromolecular complex assemblyGO:00650031930.086
meiotic cell cycleGO:00513213350.085
purine nucleotide metabolic processGO:0006163950.085
protein complex subunit organizationGO:00718222800.084
neuron developmentGO:00486661990.082
positive regulation of cellular processGO:00485223320.081
actin filament based processGO:00300291910.081
nucleoside monophosphate metabolic processGO:0009123460.080
nucleobase containing compound metabolic processGO:00061394060.079
oogenesisGO:00484772290.079
sexual reproductionGO:00199535460.078
nucleobase containing compound catabolic processGO:00346551140.077
molting cycleGO:00423032810.077
tissue developmentGO:00098881120.076
Zebrafish
organic cyclic compound biosynthetic processGO:19013621950.075
positive regulation of developmental processGO:00510944080.074
purine nucleoside monophosphate metabolic processGO:0009126430.073
cellular response to chemical stimulusGO:00708871290.071
reproductive behaviorGO:00190983870.071
response to osmotic stressGO:0006970290.071
canonical wnt signaling pathwayGO:006007030.069
purine nucleoside monophosphate catabolic processGO:0009128280.069
neurogenesisGO:00220082360.068
cellular protein complex assemblyGO:00436231780.068
regulation of rna metabolic processGO:00512521730.068
positive regulation of multicellular organismal processGO:00512404170.067
eating behaviorGO:0042755590.066
meiotic nuclear divisionGO:00071263000.066
regulation of macromolecule biosynthetic processGO:00105561890.065
cell morphogenesis involved in differentiationGO:00009041120.065
transcription dna templatedGO:00063511680.065
post embryonic organ developmentGO:00485693360.064
regulation of hydrolase activityGO:0051336450.064
macromolecule localizationGO:00330367710.064
atp catabolic processGO:0006200270.063
head developmentGO:006032210.063
cellular protein modification processGO:00064642070.063
single organism transportGO:00447654470.062
regulation of response to stimulusGO:00485832430.062
regulation of anatomical structure morphogenesisGO:0022603510.062
phosphate containing compound metabolic processGO:00067962320.062
phosphorus metabolic processGO:00067932320.061
ion transportGO:00068111130.061
cellular nitrogen compound biosynthetic processGO:00442711920.061
organelle assemblyGO:00709252140.061
aromatic compound biosynthetic processGO:00194381920.061
myosin filament assemblyGO:00310341380.060
positive regulation of catabolic processGO:0009896380.060
neuron projection developmentGO:00311751870.060
maintenance of locationGO:00512355800.060
purine ribonucleoside monophosphate catabolic processGO:0009169280.060
rna biosynthetic processGO:00327741690.059
germ cell developmentGO:00072813510.059
defense response to other organismGO:00985421000.058
programmed cell deathGO:00125015000.057
multicellular organism growthGO:00352643850.056
regulation of biosynthetic processGO:00098891890.055
cell cell signalingGO:00072671180.054
regulation of transportGO:0051049910.054
inductive cell migrationGO:00400391450.054
secretionGO:00469031470.053
pharyngeal pumpingGO:0043050580.051
lipid storageGO:00199155650.051
regulation of phosphorus metabolic processGO:0051174810.050
protein complex biogenesisGO:00702711860.049
regulation of multicellular organism growthGO:00400143730.049
response to chemicalGO:00422213560.048
protein catabolic processGO:00301631620.048
lipid localizationGO:00108765730.047
transcription from rna polymerase ii promoterGO:00063661490.047
cellular component biogenesisGO:00440852970.047
regulation of muscle system processGO:0090257200.047
regulation of nucleotide metabolic processGO:0006140370.046
actin filament based movementGO:003004840.046
cell surface receptor signaling pathwayGO:00071661490.045
actin filament organizationGO:0007015210.045
negative regulation of metabolic processGO:00098922400.045
purine containing compound metabolic processGO:0072521950.045
regulation of cellular catabolic processGO:0031329510.045
muscle fiber developmentGO:004874720.044
regulation of muscle cell differentiationGO:005114710.044
gamete generationGO:00072764610.043
signal transductionGO:00071653170.043
cell migrationGO:00164773060.043
positive regulation of growthGO:00459273690.041
protein localizationGO:00081042050.041
molting cycle collagen and cuticulin based cuticleGO:00189962810.041
striated muscle contractionGO:0006941170.041
rna metabolic processGO:00160702280.040
negative regulation of macromolecule biosynthetic processGO:0010558650.040
regulation of atpase activityGO:004346230.040
cellular component assembly involved in morphogenesisGO:00109271830.040
positive regulation of nitrogen compound metabolic processGO:00511731340.038
positive regulation of cellular metabolic processGO:00313251780.037
chemotaxisGO:00069351200.037
regulation of gene expressionGO:00104683660.037
positive regulation of locomotionGO:0040017420.037
skeletal myofibril assemblyGO:001486670.037
negative regulation of multicellular organismal processGO:00512412360.036
apoptotic processGO:00069154780.036
single fertilizationGO:0007338610.036
positive regulation of developmental growthGO:00486393540.035
negative regulation of cellular metabolic processGO:0031324950.035
ribonucleoside monophosphate catabolic processGO:0009158280.035
lamellipodium organizationGO:009758120.035
regulation of transcription dna templatedGO:00063551640.035
cell recognitionGO:0008037850.034
system processGO:00030081360.034
Zebrafish
myosin filament organizationGO:00310331380.034
response to abiotic stimulusGO:00096281520.034
multi organism reproductive behaviorGO:00447053870.033
regulation of actin cytoskeleton organizationGO:0032956170.033
regulation of localizationGO:00328791940.033
axonogenesisGO:00074091020.033
regulation of behaviorGO:0050795970.033
cell divisionGO:00513012620.032
macromolecule modificationGO:00434122180.032
muscle organ morphogenesisGO:004864440.032
striated muscle myosin thick filament assemblyGO:00716881380.032
defense response to gram negative bacteriumGO:0050829640.031
feeding behaviorGO:0007631700.031
response to heatGO:0009408500.031
small gtpase mediated signal transductionGO:0007264320.031
positive regulation of multicellular organism growthGO:00400183520.031
gene expressionGO:00104674120.030
negative regulation of developmental processGO:00510932270.029
regulation of gene expression epigeneticGO:00400291630.029
defense response to bacteriumGO:0042742860.029
innate immune responseGO:00450871900.029
regulation of catalytic activityGO:0050790780.029
regulation of phosphate metabolic processGO:0019220810.029
organ morphogenesisGO:0009887670.029
regulation of lamellipodium organizationGO:190274310.029
response to other organismGO:00517071010.029
regulation of small gtpase mediated signal transductionGO:0051056410.028
phagocytosisGO:00069091150.028
neuron recognitionGO:0008038830.028
defense responseGO:00069522960.028
regulation of signalingGO:00230511720.028
cell morphogenesisGO:00009021630.027
regulation of feeding behaviorGO:0060259380.027
response to biotic stimulusGO:00096071010.027
regulation of synapse assemblyGO:005196320.026
ribonucleoprotein complex assemblyGO:002261840.026
cation transportGO:0006812780.026
muscle organ developmentGO:0007517260.026
Zebrafish
response to external stimulusGO:00096052890.026
regulation of cell cycleGO:00517261940.025
positive regulation of cell migrationGO:003033530.025
cell growthGO:0016049440.025
cation transmembrane transportGO:0098655590.025
ras protein signal transductionGO:0007265310.024
regulation of cell proliferationGO:00421271050.024
regulation of meiotic cell cycleGO:00514451360.024
regulation of response to woundingGO:190303410.023
guanosine containing compound catabolic processGO:1901069480.023
response to external biotic stimulusGO:00432071010.023
taxisGO:00423301280.023
macromolecule catabolic processGO:00090572020.022
posttranscriptional regulation of gene expressionGO:00106081660.022
membrane organizationGO:00610241350.022
response to bacteriumGO:0009617860.022
regulation of cell projection assemblyGO:006049130.022
cell motilityGO:00488703130.022
regulation of cellular component biogenesisGO:0044087260.022
regulation of cell morphogenesisGO:0022604400.022
negative regulation of macromolecule metabolic processGO:00106052290.022
regulation of signal transductionGO:00099661350.022
positive regulation of cellular biosynthetic processGO:00313281090.022
regulation of reproductive processGO:2000241660.022
oxoacid metabolic processGO:0043436470.022
purine ribonucleoside monophosphate metabolic processGO:0009167430.021
negative regulation of cellular processGO:00485232390.021
organic acid metabolic processGO:0006082470.021
regulation of pharyngeal pumpingGO:0043051360.021
regulation of multi organism processGO:0043900690.021
regulation of gtp catabolic processGO:0033124320.021
positive regulation of nucleotide catabolic processGO:0030813280.021
positive regulation of biosynthetic processGO:00098911090.021
positive regulation of purine nucleotide metabolic processGO:1900544280.020
regulation of cell differentiationGO:0045595810.020
engulfment of apoptotic cellGO:0043652940.020
cell type specific apoptotic processGO:009728540.020
organelle fissionGO:00482853630.020
regulation of system processGO:0044057270.020
oxidation reduction processGO:0055114590.020
cell morphogenesis involved in neuron differentiationGO:00486671110.020
wnt signaling pathwayGO:0016055270.020
regulation of cellular ketone metabolic processGO:001056530.020
regulation of cell communicationGO:00106461760.019
regulation of gtpase activityGO:0043087300.019
single organism membrane organizationGO:0044802350.019
positive regulation of nucleoside metabolic processGO:0045979280.019
regulation of organ growthGO:004662050.019
organic substance transportGO:00717021130.019
response to woundingGO:000961140.019
positive regulation of cellular catabolic processGO:0031331350.019
rna interferenceGO:00162461370.019
enzyme linked receptor protein signaling pathwayGO:0007167500.019
male anatomical structure morphogenesisGO:0090598780.019
regulation of nematode larval developmentGO:00610622600.019
single organism biosynthetic processGO:0044711910.018
regulation of cell migrationGO:0030334550.018
cellular protein metabolic processGO:00442672790.018
protein modification processGO:00362112070.018
negative regulation of locomotionGO:0040013210.018
membrane invaginationGO:0010324980.018
cellular protein localizationGO:0034613750.018
regulation of cellular component movementGO:0051270620.018
gtp catabolic processGO:0006184460.018
positive regulation of metabolic processGO:00098931870.018
positive regulation of cell communicationGO:0010647690.018
positive regulation of gtpase activityGO:0043547280.017
positive regulation of hydrolase activityGO:0051345380.017
immune responseGO:00069551920.017
posttranscriptional gene silencing by rnaGO:00351941430.017
regulation of cell cycle processGO:00105641450.017
positive regulation of cell deathGO:0010942380.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.017
regulation of cytoplasmic transportGO:190364930.017
vulval developmentGO:00400253330.017
single organism cellular localizationGO:1902580720.017
response to topologically incorrect proteinGO:0035966820.017
lamellipodium assemblyGO:003003220.017
regulation of post embryonic developmentGO:00485802600.017
negative regulation of gene expressionGO:00106292170.017
guanosine containing compound metabolic processGO:1901068490.017
oocyte differentiationGO:0009994450.017
cellular amine metabolic processGO:0044106150.016
regulation of striated muscle contractionGO:000694240.016
multicellular organismal movementGO:005087920.016
positive regulation of purine nucleotide catabolic processGO:0033123280.016
regulation of ras gtpase activityGO:0032318210.016
synaptic transmissionGO:00072681060.016
regulation of cellular amine metabolic processGO:003323800.016
negative regulation of nematode larval developmentGO:00610642080.016
chromosome segregationGO:00070591800.016
regulation of cellular amino acid metabolic processGO:000652100.016
positive regulation of gene expressionGO:00106281120.016
regulation of ras protein signal transductionGO:0046578410.016
glycoprotein biosynthetic processGO:0009101280.016
positive regulation of nucleobase containing compound metabolic processGO:00459351340.016
nucleoside monophosphate catabolic processGO:0009125280.016
cellular response to stressGO:00335541620.016
protein oligomerizationGO:005125940.016
axonal fasciculationGO:0007413790.015
regulation of apoptotic signaling pathwayGO:200123310.015
regulation of cell developmentGO:0060284490.015
regulation of cellular localizationGO:0060341420.015
adult locomotory behaviorGO:000834410.015
gene silencing by rnaGO:00310471430.015
rho protein signal transductionGO:000726620.015
spindle localizationGO:0051653510.015
positive regulation of vulval developmentGO:0040026520.015
amine metabolic processGO:0009308150.015
regulation of cell divisionGO:00513021420.015
adult behaviorGO:003053430.015
meiotic cell cycle processGO:19030461700.015
cuticle developmentGO:00423351000.014
gene silencingGO:00164581430.014
cytokinesisGO:0000910800.014
neuromuscular junction developmentGO:000752820.014
negative regulation of nitrogen compound metabolic processGO:0051172630.014
carboxylic acid metabolic processGO:0019752340.014
positive regulation of gtp catabolic processGO:0033126280.014
rna localizationGO:000640330.014
regulation of calcium ion transportGO:005192430.014
synaptic growth at neuromuscular junctionGO:005112410.014
positive regulation of nematode larval developmentGO:0061063540.014
neurological system processGO:0050877530.014
nervous system developmentGO:00073992530.013
excretionGO:0007588490.013
fertilizationGO:0009566630.013
sensory organ morphogenesisGO:009059620.013
oocyte developmentGO:0048599440.013
necrotic cell deathGO:0070265290.013
neuron projection morphogenesisGO:00488121140.013
regulation of protein stabilityGO:003164730.013
organ growthGO:003526550.013
localization of cellGO:00516743130.013
intracellular signal transductionGO:0035556960.013
cellular macromolecule localizationGO:0070727750.013
pronuclear migrationGO:0035046510.013
axon guidanceGO:0007411820.013
protein polymerizationGO:0051258260.013
regulation of epithelial cell proliferationGO:005067810.013
regulation of cell deathGO:0010941650.013
intracellular transportGO:0046907770.013
digestive system developmentGO:00551231220.013
actin filament bundle assemblyGO:005101730.013
bmp signaling pathwayGO:003050930.013
negative regulation of gene expression epigeneticGO:004581420.013
negative regulation of cellular biosynthetic processGO:0031327650.012
nuclear migrationGO:0007097540.012
meiotic chromosome segregationGO:00451321390.012
defense response to fungusGO:0050832190.012
response to organic substanceGO:00100331310.012
regulation of anatomical structure sizeGO:0090066460.012
ovulationGO:0030728330.012
dauer larval developmentGO:0040024920.012
regulation of nuclear divisionGO:00517831150.012
cellular response to organic substanceGO:00713101190.012
cytoskeleton dependent cytokinesisGO:0061640350.012
response to fungusGO:0009620200.012
cellular amino acid metabolic processGO:0006520150.011
dna metabolic processGO:0006259740.011
defecationGO:0030421470.011
regulation of cellular component sizeGO:0032535400.011
positive regulation of striated muscle contractionGO:004598920.011
epithelial cell proliferationGO:005067310.011
regulation of ovipositionGO:0046662430.011
collagen and cuticulin based cuticle developmentGO:0040002990.011
apoptotic cell clearanceGO:00432771110.011
cell proliferationGO:00082831160.011
cytosolic calcium ion homeostasisGO:005148020.011
posttranscriptional gene silencingGO:00164411430.011
embryonic body morphogenesisGO:0010172490.011
regulation of meiosisGO:0040020940.011
regulation of cell motilityGO:2000145570.011
regulation of lamellipodium assemblyGO:001059110.011
regenerationGO:003109940.011
immune response regulating signaling pathwayGO:000276410.011
negative regulation of cell communicationGO:0010648610.010
negative regulation of transcription dna templatedGO:0045892530.010
muscle attachmentGO:001620330.010
establishment of mitotic spindle orientationGO:0000132280.010
carbohydrate metabolic processGO:0005975340.010
neuron projection guidanceGO:0097485820.010
negative regulation of vulval developmentGO:00400272060.010
cell substrate adhesionGO:003158910.010
regulation of ion transportGO:0043269390.010

unc-45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.012